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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77205825
log Bayes Factor = 25.6929
Chromosome 8   position 140,470,489  (GRCh37) Explore rs77205825 on Ensembl!
Variant rs77205825 is part of Cluster X0139

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
0.997 0.003 0.000
I30-I52 Other forms of heart disease
0.997 0.003 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.997 0.003 0.000
I25 Chronic ischaemic heart disease
0.996 0.004 0.000
Z96 Presence of other functional implants
0.995 0.005 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.993 0.007 0.000
I60-I69 Cerebrovascular diseases
0.991 0.009 0.000
Chapter VI Diseases of the nervous system
0.991 0.009 0.000
M45-M49 Spondylopathies
0.990 0.010 0.000
Z96.1 Presence of intraocular lens
0.990 0.010 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.989 0.011 0.000
H30-H36 Disorders of choroid and retina
0.986 0.014 0.000
M70-M79 Other soft tissue disorders
0.984 0.016 0.000
Chapter II Neoplasms
0.984 0.016 0.000
Chapter X Diseases of the respiratory system
0.980 0.020 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.979 0.021 0.000
R42 Dizziness and giddiness
0.976 0.024 0.000
M47 Spondylosis
0.971 0.029 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.971 0.029 0.000
Z86 Personal history of certain other diseases
0.969 0.031 0.000
I21 Acute myocardial infarction
0.966 0.034 0.000
I20 Angina pectoris
0.966 0.034 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.957 0.043 0.000
M47.8 Other spondylosis
0.954 0.046 0.000
I67 Other cerebrovascular diseases
0.953 0.047 0.000
H33 Retinal detachments and breaks
0.952 0.048 0.000
I25.2 Old myocardial infarction
0.950 0.050 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.949 0.051 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.948 0.052 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.945 0.055 0.000
I49 Other cardiac arrhythmias
0.945 0.055 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.944 0.056 0.000
M75 Shoulder lesions
0.942 0.058 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.940 0.060 0.000
H35 Other retinal disorders
0.940 0.060 0.000
Z53.9 Procedure not carried out, unspecified reason
0.940 0.060 0.000
I20.9 Angina pectoris, unspecified
0.938 0.062 0.000
I25.1 Atherosclerotic heart disease
0.935 0.065 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.932 0.068 0.000
Z53.0 Procedure not carried out because of contraindication
0.930 0.070 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.930 0.070 0.000
Z86.7 Personal history of diseases of the circulatory system
0.929 0.071 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.928 0.072 0.000
J09-J18 Influenza and pneumonia
0.927 0.073 0.000
J95-J99 Other diseases of the respiratory system
0.926 0.074 0.000
R50-R69 General symptoms and signs
0.924 0.076 0.000
R73 Elevated blood glucose level
0.924 0.076 0.000
I31 Other diseases of pericardium
0.923 0.077 0.000
R07 Pain in throat and chest
0.923 0.077 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.922 0.078 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.921 0.079 0.000
R01 Cardiac murmurs and other cardiac sounds
0.921 0.079 0.000
D00-D09 In situ neoplasms
0.921 0.079 0.000
R04 Haemorrhage from respiratory passages
0.919 0.081 0.000
I77 Other disorders of arteries and arterioles
0.918 0.082 0.000
I67.9 Cerebrovascular disease, unspecified
0.916 0.084 0.000
H35.3 Degeneration of macula and posterior pole
0.910 0.090 0.000
Chapter V Mental and behavioural disorders
0.907 0.093 0.000
I44 Atrioventricular and left bundle-branch block
0.906 0.094 0.000
R07.2 Precordial pain
0.903 0.097 0.000
M05-M14 Inflammatory polyarthropathies
0.899 0.101 0.000
M47.86 Other spondylosis (Lumbar region)
0.897 0.103 0.000
R04.2 Haemoptysis
0.896 0.104 0.000
G90-G99 Other disorders of the nervous system
0.896 0.104 0.000
R69 Unknown and unspecified causes of morbidity
0.896 0.104 0.000
I69 Sequelae of cerebrovascular disease
0.894 0.106 0.000
M80-M85 Disorders of bone density and structure
0.893 0.107 0.000
Z96.0 Presence of urogenital implants
0.892 0.108 0.000
C80 Malignant neoplasm without specification of site
0.892 0.108 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.890 0.110 0.000
R40 Somnolence, stupor and coma
0.889 0.111 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.889 0.111 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.889 0.111 0.000
Z03.4 Observation for suspected myocardial infarction
0.887 0.113 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.884 0.116 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.883 0.117 0.000
I42 Cardiomyopathy
0.881 0.119 0.000
H43-H45 Disorders of vitreous body and globe
0.879 0.121 0.000
I26 Pulmonary embolism
0.872 0.128 0.000
R01.1 Cardiac murmur, unspecified
0.870 0.130 0.000
Chapter I Certain infectious and parasitic diseases
0.868 0.132 0.000
I05-I09 Chronic rheumatic heart diseases
0.867 0.133 0.000
M46 Other inflammatory spondylopathies
0.866 0.134 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.864 0.136 0.000
J98 Other respiratory disorders
0.861 0.139 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.857 0.143 0.000
R55 Syncope and collapse
0.856 0.144 0.000
I31.3 Pericardial effusion (noninflammatory)
0.856 0.144 0.000
H33.3 Retinal breaks without detachment
0.855 0.145 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.855 0.145 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.855 0.145 0.000
Z87 Personal history of other diseases and conditions
0.854 0.146 0.000
H53-H54 Visual disturbances and blindness
0.853 0.147 0.000
I71 Aortic aneurysm and dissection
0.850 0.150 0.000
M75.0 Adhesive capsulitis of shoulder
0.850 0.150 0.000
M47.82 Other spondylosis (Cervical region)
0.848 0.152 0.000
I45 Other conduction disorders
0.847 0.153 0.000
S20-S29 Injuries to the thorax
0.846 0.154 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.846 0.154 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.845 0.155 0.000
I20.8 Other forms of angina pectoris
0.844 0.156 0.000
R73.0 Abnormal glucose tolerance test
0.841 0.159 0.000
Z96.7 Presence of other bone and tendon implants
0.841 0.159 0.000
S40-S49 Injuries to the shoulder and upper arm
0.839 0.161 0.000
M77 Other enthesopathies
0.836 0.163 0.000
M75.5 Bursitis of shoulder
0.833 0.167 0.000
C64-C68 Malignant neoplasms of urinary tract
0.833 0.167 0.000
H25-H28 Disorders of lens
0.833 0.167 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.832 0.168 0.000
R05 Cough
0.832 0.168 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.832 0.168 0.000
I73 Other peripheral vascular diseases
0.830 0.170 0.000
J18 Pneumonia, organism unspecified
0.830 0.170 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.829 0.171 0.000
J90-J94 Other diseases of pleura
0.827 0.173 0.000
Z57 Occupational exposure to risk-factors
0.826 0.174 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.824 0.176 0.000
I49.3 Ventricular premature depolarisation
0.822 0.178 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.820 0.180 0.000
Z89 Acquired absence of limb
0.819 0.181 0.000
I44.0 Atrioventricular block, first degree
0.818 0.182 0.000
R73.9 Hyperglycaemia, unspecified
0.818 0.182 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.817 0.183 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.817 0.183 0.000
M40-M43 Deforming dorsopathies
0.816 0.184 0.000
M86-M90 Other osteopathies
0.814 0.186 0.000
G30-G32 Other degenerative diseases of the nervous system
0.813 0.187 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.813 0.187 0.000
J00-J06 Acute upper respiratory infections
0.812 0.188 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.811 0.189 0.000
I50 Heart failure
0.810 0.190 0.000
L03 Cellulitis
0.810 0.190 0.000
M91-M94 Chondropathies
0.810 0.190 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.810 0.190 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.809 0.191 0.000
I49.8 Other specified cardiac arrhythmias
0.808 0.192 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.805 0.195 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.804 0.196 0.000
J18.9 Pneumonia, unspecified
0.803 0.197 0.000
C80.9 Malignant neoplasm, unspecified
0.801 0.199 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.799 0.201 0.000
H33.4 Traction detachment of retina
0.799 0.201 0.000
J10 Influenza due to identified influenza virus
0.798 0.202 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.795 0.205 0.000
H43 Disorders of vitreous body
0.794 0.206 0.000
M48 Other spondylopathies
0.794 0.206 0.000
Z92 Personal history of medical treatment
0.793 0.207 0.000
M13 Other arthritis
0.792 0.208 0.000
M15-M19 Arthrosis
0.791 0.209 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.790 0.209 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.790 0.210 0.000
D05 Carcinoma in situ of breast
0.790 0.210 0.000
F30-F39 Mood [affective] disorders
0.786 0.214 0.000
I77.1 Stricture of artery
0.784 0.216 0.000
H33.2 Serous retinal detachment
0.783 0.217 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.781 0.219 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.781 0.219 0.000
I22 Subsequent myocardial infarction
0.781 0.219 0.000
Z13 Special screening examination for other diseases and disorders
0.780 0.220 0.000
L03.1 Cellulitis of other parts of limb
0.778 0.222 0.000
I73.9 Peripheral vascular disease, unspecified
0.778 0.222 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.777 0.223 0.000
C15-C26 Malignant neoplasms of digestive organs
0.777 0.223 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.776 0.224 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.776 0.224 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.776 0.224 0.000
R40.2 Coma, unspecified
0.774 0.226 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.774 0.226 0.000
D03 Melanoma in situ
0.773 0.227 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.773 0.227 0.000
M47.2 Other spondylosis with radiculopathy
0.771 0.229 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.771 0.229 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.771 0.229 0.000
L20-L30 Dermatitis and eczema
0.771 0.229 0.000
R25 Abnormal involuntary movements
0.771 0.229 0.000
I67.1 Cerebral aneurysm, nonruptured
0.771 0.229 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.770 0.230 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.770 0.230 0.000
I63 Cerebral infarction
0.769 0.231 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.768 0.232 0.000
H35.5 Hereditary retinal dystrophy
0.768 0.232 0.000
A30-A49 Other bacterial diseases
0.767 0.233 0.000
I42.0 Dilated cardiomyopathy
0.766 0.234 0.000
H33.0 Retinal detachment with retinal break
0.765 0.235 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.765 0.235 0.000
C78.7 Secondary malignant neoplasm of liver
0.763 0.237 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.762 0.238 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.762 0.238 0.000
C79 Secondary malignant neoplasm of other sites
0.762 0.238 0.000
I38 Endocarditis, valve unspecified
0.760 0.240 0.000
G82 Paraplegia and tetraplegia
0.759 0.241 0.000
M71 Other bursopathies
0.759 0.241 0.000
M75.1 Rotator cuff syndrome
0.759 0.241 0.000
M19 Other arthrosis
0.756 0.243 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.756 0.244 0.000
R79 Other abnormal findings of blood chemistry
0.756 0.244 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.756 0.244 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.755 0.245 0.000
I49.0 Ventricular fibrillation and flutter
0.755 0.245 0.000
Z93 Artificial opening status
0.754 0.246 0.000
I44.2 Atrioventricular block, complete
0.753 0.247 0.000
I77.8 Other specified disorders of arteries and arterioles
0.753 0.247 0.000
S10-S19 Injuries to the neck
0.752 0.248 0.000
H54 Blindness and low vision
0.752 0.248 0.000
L40-L45 Papulosquamous disorders
0.751 0.248 0.000
R54 Senility
0.751 0.249 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.751 0.249 0.000
M84 Disorders of continuity of bone
0.750 0.249 0.000
H55-H59 Other disorders of eye and adnexa
0.750 0.249 0.000
M65-M68 Disorders of synovium and tendon
0.750 0.250 0.000
M47.1 Other spondylosis with myelopathy
0.749 0.251 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.749 0.251 0.000
S70-S79 Injuries to the hip and thigh
0.747 0.253 0.000
R29.6 Tendency to fall, not elsewhere classified
0.746 0.254 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.746 0.254 0.000
R45 Symptoms and signs involving emotional state
0.746 0.254 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.746 0.254 0.000
Z73 Problems related to life-management difficulty
0.746 0.254 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.746 0.254 0.000
I72 Other aneurysm
0.745 0.255 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.744 0.256 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.744 0.256 0.000
R06 Abnormalities of breathing
0.743 0.257 0.000
Z34 Supervision of normal pregnancy
0.743 0.257 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.742 0.258 0.000
Z57.2 Occupational exposure to dust
0.740 0.260 0.000
D09 Carcinoma in situ of other and unspecified sites
0.740 0.260 0.000
I69.3 Sequelae of cerebral infarction
0.738 0.262 0.000
Z97 Presence of other devices
0.737 0.262 0.000
R68 Other general symptoms and signs
0.737 0.263 0.000
I30 Acute pericarditis
0.737 0.263 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.736 0.264 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.735 0.265 0.000
I08 Multiple valve diseases
0.735 0.265 0.000
S42 Fracture of shoulder and upper arm
0.734 0.266 0.000
Z30 Contraceptive management
0.734 0.266 0.000
Z51 Other medical care
0.733 0.267 0.000
Z92.3 Personal history of irradiation
0.733 0.267 0.000
I05 Rheumatic mitral valve diseases
0.733 0.267 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.733 0.267 0.000
R40.0 Somnolence
0.732 0.267 0.000
J92 Pleural plaque
0.732 0.268 0.000
Z96.8 Presence of other specified functional implants
0.732 0.268 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.731 0.269 0.000
R76 Other abnormal immunological findings in serum
0.731 0.269 0.000
G20-G26 Extrapyramidal and movement disorders
0.731 0.269 0.000
E65-E68 Obesity and other hyperalimentation
0.731 0.269 0.000
I77.6 Arteritis, unspecified
0.730 0.270 0.000
Chapter XXII Codes for special purposes
0.730 0.270 0.000
Z03.3 Observation for suspected nervous system disorder
0.730 0.270 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.730 0.270 0.000
M77.1 Lateral epicondylitis
0.729 0.271 0.000
I70 Atherosclerosis
0.728 0.272 0.000
F32 Depressive episode
0.722 0.278 0.000
I78 Diseases of capillaries
0.722 0.278 0.000
T66-T78 Other and unspecified effects of external causes
0.721 0.279 0.000
Z94 Transplanted organ and tissue status
0.721 0.279 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.721 0.279 0.000
Z54 Convalescence
0.720 0.280 0.000
I49.9 Cardiac arrhythmia, unspecified
0.720 0.280 0.000
I27 Other pulmonary heart diseases
0.720 0.280 0.000
C51-C58 Malignant neoplasms of female genital organs
0.719 0.281 0.000
I42.2 Other hypertrophic cardiomyopathy
0.718 0.282 0.000
M81 Osteoporosis without pathological fracture
0.718 0.282 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.717 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I33 Acute and subacute endocarditis
0.716 0.284 0.000
I34 Nonrheumatic mitral valve disorders
0.716 0.284 0.000
I31.9 Disease of pericardium, unspecified
0.716 0.284 0.000
M19.9 Arthrosis, unspecified
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.715 0.285 0.000
I48 Atrial fibrillation and flutter
0.715 0.285 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.715 0.285 0.000
I41 Myocarditis in diseases classified elsewhere
0.715 0.285 0.000
I40 Acute myocarditis
0.715 0.285 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.715 0.285 0.000
I37 Pulmonary valve disorders
0.715 0.285 0.000
I36 Nonrheumatic tricuspid valve disorders
0.715 0.285 0.000
I32 Pericarditis in diseases classified elsewhere
0.715 0.285 0.000
Z84 Family history of other conditions
0.715 0.285 0.000
Z81 Family history of mental and behavioural disorders
0.715 0.285 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.715 0.285 0.000
A00-A09 Intestinal infectious diseases
0.715 0.285 0.000
I25.6 Silent myocardial ischaemia
0.714 0.286 0.000
I25.4 Coronary artery aneurysm
0.714 0.286 0.000
I25.3 Aneurysm of heart
0.714 0.286 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.714 0.286 0.000
Z13.9 Special screening examination, unspecified
0.714 0.286 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.714 0.286 0.000
Z96.9 Presence of functional implant, unspecified
0.713 0.286 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.713 0.286 0.000
Z96.4 Presence of endocrine implants
0.713 0.286 0.000
Z96.3 Presence of artificial larynx
0.713 0.286 0.000
Z96.2 Presence of otological and audiological implants
0.713 0.286 0.000
M75.2 Bicipital tendinitis
0.713 0.287 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.713 0.287 0.000
J40-J47 Chronic lower respiratory diseases
0.713 0.287 0.000
G83 Other paralytic syndromes
0.713 0.287 0.000
E20-E35 Disorders of other endocrine glands
0.713 0.287 0.000
G40-G47 Episodic and paroxysmal disorders
0.713 0.287 0.000
C78.0 Secondary malignant neoplasm of lung
0.712 0.288 0.000
J20-J22 Other acute lower respiratory infections
0.711 0.289 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.711 0.289 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.711 0.289 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.711 0.289 0.000
M49 Spondylopathies in diseases classified elsewhere
0.710 0.290 0.000
I25.5 Ischaemic cardiomyopathy
0.710 0.290 0.000
R46 Symptoms and signs involving appearance and behaviour
0.709 0.291 0.000
R43 Disturbances of smell and taste
0.709 0.291 0.000
I21.9 Acute myocardial infarction, unspecified
0.709 0.291 0.000
I44.1 Atrioventricular block, second degree
0.708 0.292 0.000
M75.3 Calcific tendinitis of shoulder
0.708 0.292 0.000
G62 Other polyneuropathies
0.708 0.292 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.707 0.293 0.000
H31 Other disorders of choroid
0.707 0.293 0.000
H30 Chorioretinal inflammation
0.707 0.293 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.707 0.293 0.000
J98.1 Pulmonary collapse
0.706 0.294 0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.706 0.294 0.000
M76 Enthesopathies of lower limb, excluding foot
0.705 0.295 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.705 0.295 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.705 0.295 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.705 0.295 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.705 0.295 0.000
R07.0 Pain in throat
0.705 0.295 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.704 0.296 0.000
R47-R49 Symptoms and signs involving speech and voice
0.704 0.296 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.703 0.297 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.702 0.298 0.000
Chapter VIII Diseases of the ear and mastoid process
0.701 0.299 0.000
R26 Abnormalities of gait and mobility
0.700 0.300 0.000
B35-B49 Mycoses
0.700 0.300 0.000
H52 Disorders of refraction and accommodation
0.700 0.300 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.700 0.300 0.000
M72 Fibroblastic disorders
0.700 0.300 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.700 0.300 0.000
M10 Gout
0.700 0.300 0.000
J98.4 Other disorders of lung
0.699 0.301 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.696 0.303 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.696 0.304 0.000
R77 Other abnormalities of plasma proteins
0.696 0.304 0.000
R74 Abnormal serum enzyme levels
0.696 0.304 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.696 0.304 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.696 0.304 0.000
R71 Abnormality of red blood cells
0.696 0.304 0.000
L03.9 Cellulitis, unspecified
0.696 0.304 0.000
D06 Carcinoma in situ of cervix uteri
0.695 0.304 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.695 0.305 0.000
M80 Osteoporosis with pathological fracture
0.695 0.305 0.000
Z57.3 Occupational exposure to other air contaminants
0.695 0.305 0.000
I45.2 Bifascicular block
0.695 0.305 0.000
I67.2 Cerebral atherosclerosis
0.694 0.306 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.693 0.307 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.693 0.307 0.000
I65.2 Occlusion and stenosis of carotid artery
0.693 0.307 0.000
H43.8 Other disorders of vitreous body
0.692 0.308 0.000
G70-G73 Diseases of myoneural junction and muscle
0.691 0.309 0.000
I49.4 Other and unspecified premature depolarisation
0.691 0.309 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.691 0.309 0.000
R57 Shock, not elsewhere classified
0.689 0.310 0.000
M05 Seropositive rheumatoid arthritis
0.689 0.311 0.000
I10-I15 Hypertensive diseases
0.689 0.311 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.689 0.311 0.000
M13.9 Arthritis, unspecified
0.688 0.312 0.000
E66 Obesity
0.688 0.312 0.000
B25-B34 Other viral diseases
0.688 0.312 0.000
D45 Polycythaemia vera
0.688 0.312 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.687 0.313 0.000
Z49 Care involving dialysis
0.687 0.313 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.686 0.313 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.686 0.314 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.685 0.315 0.000
Z03.8 Observation for other suspected diseases and conditions
0.685 0.315 0.000
L40 Psoriasis
0.685 0.315 0.000
C34 Malignant neoplasm of bronchus and lung
0.685 0.315 0.000
M47.89 Other spondylosis (Site unspecified)
0.684 0.316 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.684 0.316 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.684 0.316 0.000
M47.84 Other spondylosis (Thoracic region)
0.684 0.316 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.684 0.316 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.684 0.316 0.000
Z75 Problems related to medical facilities and other health care
0.684 0.316 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.684 0.316 0.000
Z74 Problems related to care-provider dependency
0.683 0.317 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.683 0.317 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.683 0.317 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.683 0.317 0.000
I67.5 Moyamoya disease
0.683 0.317 0.000
I67.4 Hypertensive encephalopathy
0.683 0.317 0.000
I67.3 Progressive vascular leukoencephalopathy
0.683 0.317 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.683 0.317 0.000
H33.5 Other retinal detachments
0.683 0.317 0.000
H33.1 Retinoschisis and retinal cysts
0.683 0.317 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.683 0.317 0.000
I46 Cardiac arrest
0.683 0.317 0.000
G93 Other disorders of brain
0.681 0.319 0.000
H10-H13 Disorders of conjunctiva
0.681 0.319 0.000
Z63 Other problems related to primary support group, including family circumstances
0.681 0.319 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.679 0.321 0.000
C78.2 Secondary malignant neoplasm of pleura
0.679 0.321 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.678 0.322 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.678 0.322 0.000
Z44 Fitting and adjustment of external prosthetic device
0.678 0.322 0.000
J44 Other chronic obstructive pulmonary disease
0.678 0.322 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.677 0.322 0.000
I49.2 Junctional premature depolarisation
0.677 0.323 0.000
I49.1 Atrial premature depolarisation
0.677 0.323 0.000
Z51.5 Palliative care
0.677 0.323 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.677 0.323 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.677 0.323 0.000
M75.8 Other shoulder lesions
0.676 0.324 0.000
M75.9 Shoulder lesion, unspecified
0.676 0.324 0.000
I80 Phlebitis and thrombophlebitis
0.676 0.324 0.000
T79-T79 Certain early complications of trauma
0.674 0.326 0.000
T33-T35 Frostbite
0.674 0.326 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.674 0.326 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.674 0.326 0.000
T00-T07 Injuries involving multiple body regions
0.674 0.326 0.000
M50-M54 Other dorsopathies
0.674 0.326 0.000
H35.9 Retinal disorder, unspecified
0.674 0.326 0.000
H35.7 Separation of retinal layers
0.674 0.326 0.000
H35.6 Retinal haemorrhage
0.674 0.326 0.000
H35.2 Other proliferative retinopathy
0.674 0.326 0.000
H35.1 Retinopathy of prematurity
0.674 0.326 0.000
R61 Hyperhidrosis
0.674 0.326 0.000
M93 Other osteochondropathies
0.674 0.326 0.000
A41 Other septicaemia
0.673 0.327 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.671 0.329 0.000
M07 Psoriatic and enteropathic arthropathies
0.671 0.329 0.000
J98.8 Other specified respiratory disorders
0.669 0.331 0.000
I28 Other diseases of pulmonary vessels
0.668 0.332 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.668 0.332 0.000
M45 Ankylosing spondylitis
0.668 0.332 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.667 0.333 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.667 0.333 0.000
Z10 Routine general health check-up of defined subpopulation
0.666 0.333 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.666 0.334 0.000
H34 Retinal vascular occlusions
0.666 0.334 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.666 0.334 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.666 0.334 0.000
Z52 Donors of organs and tissues
0.665 0.335 0.000
J17 Pneumonia in diseases classified elsewhere
0.665 0.335 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.665 0.335 0.000
J12 Viral pneumonia, not elsewhere classified
0.665 0.335 0.000
J11 Influenza, virus not identified
0.665 0.335 0.000
J14 Pneumonia due to Haemophilus influenzae
0.665 0.335 0.000
J09 Influenza due to certain identified influenza virus
0.665 0.335 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.664 0.336 0.000
J96 Respiratory failure, not elsewhere classified
0.664 0.336 0.000
R94 Abnormal results of function studies
0.664 0.336 0.000
I20.1 Angina pectoris with documented spasm
0.663 0.337 0.000
G80 Infantile cerebral palsy
0.663 0.337 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.663 0.337 0.000
R62 Lack of expected normal physiological development
0.663 0.337 0.000
R64 Cachexia
0.663 0.337 0.000
R58 Haemorrhage, not elsewhere classified
0.663 0.337 0.000
J60-J70 Lung diseases due to external agents
0.662 0.338 0.000
S22.0 Fracture of thoracic vertebra
0.662 0.338 0.000
I49.5 Sick sinus syndrome
0.662 0.338 0.000
J00 Acute nasopharyngitis [common cold]
0.662 0.338 0.000
I31.8 Other specified diseases of pericardium
0.662 0.338 0.000
I31.2 Haemopericardium, not elsewhere classified
0.662 0.338 0.000
I31.1 Chronic constrictive pericarditis
0.662 0.338 0.000
I31.0 Chronic adhesive pericarditis
0.662 0.338 0.000
G81 Hemiplegia
0.661 0.339 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.661 0.339 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.661 0.339 0.000
Z03.0 Observation for suspected tuberculosis
0.661 0.339 0.000
M18 Arthrosis of first carpometacarpal joint
0.661 0.339 0.000
H27 Other disorders of lens
0.661 0.339 0.000
H26 Other cataract
0.661 0.339 0.000
S22.4 Multiple fractures of ribs
0.660 0.339 0.000
R01.2 Other cardiac sounds
0.660 0.340 0.000
R01.0 Benign and innocent cardiac murmurs
0.660 0.340 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.660 0.340 0.000
D04 Carcinoma in situ of skin
0.660 0.340 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.660 0.340 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.660 0.340 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.660 0.340 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.660 0.340 0.000
C73 Malignant neoplasm of thyroid gland
0.660 0.340 0.000
J95.8 Other postprocedural respiratory disorders
0.659 0.341 0.000
R04.9 Haemorrhage from respiratory passages, unspecified
0.659 0.341 0.000
R04.8 Haemorrhage from other sites in respiratory passages
0.659 0.341 0.000
R04.1 Haemorrhage from throat
0.659 0.341 0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device
0.659 0.341 0.000
J01 Acute sinusitis
0.659 0.341 0.000
I77.5 Necrosis of artery
0.658 0.342 0.000
I77.4 Coeliac artery compression syndrome
0.658 0.342 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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