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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17482753
log Bayes Factor = 3.23105
Chromosome 8   position 19,832,646  (GRCh37) Explore rs17482753 on Ensembl!
Variant rs17482753 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
0.000 0.003 0.997
I25.1 Atherosclerotic heart disease
0.000 0.004 0.996
I25 Chronic ischaemic heart disease
0.000 0.004 0.996
I21 Acute myocardial infarction
0.000 0.013 0.987
I24 Other acute ischaemic heart diseases
0.000 0.018 0.982
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.023 0.977
I24.8 Other forms of acute ischaemic heart disease
0.000 0.069 0.931
I20 Angina pectoris
0.000 0.081 0.919
I22 Subsequent myocardial infarction
0.000 0.083 0.917
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.084 0.916
I21.9 Acute myocardial infarction, unspecified
0.000 0.089 0.911
I20.9 Angina pectoris, unspecified
0.000 0.107 0.893
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.136 0.864
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.174 0.826
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.180 0.819
I25.4 Coronary artery aneurysm
0.000 0.182 0.818
E78.0 Pure hypercholesterolaemia
0.000 0.212 0.788
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.213 0.787
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.222 0.778
I25.2 Old myocardial infarction
0.000 0.226 0.774
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.234 0.766
E78.5 Hyperlipidaemia, unspecified
0.000 0.236 0.764
I20.0 Unstable angina
0.000 0.273 0.727
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.281 0.719
I23 Certain current complications following acute myocardial infarction
0.000 0.285 0.715
I25.6 Silent myocardial ischaemia
0.000 0.286 0.714
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.292 0.708
E78.2 Mixed hyperlipidaemia
0.000 0.303 0.697
I24.1 Dressler's syndrome
0.000 0.332 0.667
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.336 0.664
E78.1 Pure hyperglyceridaemia
0.000 0.350 0.649
I22.8 Subsequent myocardial infarction of other sites
0.000 0.354 0.645
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.368 0.632
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.389 0.611
I25.5 Ischaemic cardiomyopathy
0.000 0.392 0.607
E78.4 Other hyperlipidaemia
0.000 0.439 0.560
E78.6 Lipoprotein deficiency
0.000 0.442 0.558
E78.3 Hyperchylomicronaemia
0.000 0.442 0.558
I25.3 Aneurysm of heart
0.000 0.446 0.554
E78.8 Other disorders of lipoprotein metabolism
0.000 0.475 0.525
I23.8 Other current complications following acute myocardial infarction
0.000 0.487 0.512
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.487 0.512
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.487 0.512
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.487 0.512
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.487 0.512
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.487 0.512
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.487 0.512
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.487 0.512
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.506 0.494
I20.1 Angina pectoris with documented spasm
0.000 0.526 0.474
I20.8 Other forms of angina pectoris
0.000 0.526 0.474
I21.4 Acute subendocardial myocardial infarction
0.000 0.619 0.381
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.844 0.156
E70-E90 Metabolic disorders
0.000 0.931 0.069
E86 Volume depletion
0.000 0.947 0.053
E83 Disorders of mineral metabolism
0.000 0.947 0.053
E73 Lactose intolerance
0.000 0.947 0.052
E83.1 Disorders of iron metabolism
0.000 0.948 0.052
E74 Other disorders of carbohydrate metabolism
0.000 0.949 0.051
E84 Cystic fibrosis
0.000 0.950 0.050
E79 Disorders of purine and pyrimidine metabolism
0.000 0.950 0.050
E77 Disorders of glycoprotein metabolism
0.000 0.950 0.050
E76 Disorders of glycosaminoglycan metabolism
0.000 0.950 0.050
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.950 0.050
E72 Other disorders of amino-acid metabolism
0.000 0.950 0.050
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.950 0.050
E70 Disorders of aromatic amino-acid metabolism
0.000 0.950 0.050
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.950 0.050
E88 Other metabolic disorders
0.000 0.951 0.049
E85 Amyloidosis
0.000 0.954 0.046
E73.9 Lactose intolerance, unspecified
0.000 0.960 0.040
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.962 0.038
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.962 0.038
E83.8 Other disorders of mineral metabolism
0.000 0.962 0.038
E83.2 Disorders of zinc metabolism
0.000 0.962 0.038
E83.0 Disorders of copper metabolism
0.000 0.962 0.038
E73.8 Other lactose intolerance
0.000 0.962 0.038
E73.1 Secondary lactase deficiency
0.000 0.962 0.038
E73.0 Congenital lactase deficiency
0.000 0.962 0.038
E83.4 Disorders of magnesium metabolism
0.000 0.963 0.037
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.963 0.037
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.963 0.037
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.963 0.037
E74.2 Disorders of galactose metabolism
0.000 0.963 0.037
E74.1 Disorders of fructose metabolism
0.000 0.963 0.037
E74.0 Glycogen storage disease
0.000 0.963 0.037
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.963 0.037
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.964 0.036
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.964 0.036
E70.3 Albinism
0.000 0.964 0.036
E70.2 Disorders of tyrosine metabolism
0.000 0.964 0.036
E70.1 Other hyperphenylalaninaemias
0.000 0.964 0.036
E70.0 Classical phenylketonuria
0.000 0.964 0.036
E71.3 Disorders of fatty-acid metabolism
0.000 0.964 0.036
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.964 0.036
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.964 0.036
E71.0 Maple-syrup-urine disease
0.000 0.964 0.036
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.964 0.036
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.964 0.036
E72.5 Disorders of glycine metabolism
0.000 0.964 0.036
E72.4 Disorders of ornithine metabolism
0.000 0.964 0.036
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.964 0.036
E72.2 Disorders of urea cycle metabolism
0.000 0.964 0.036
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.964 0.036
E72.0 Disorders of amino-acid transport
0.000 0.964 0.036
E75.6 Lipid storage disorder, unspecified
0.000 0.964 0.036
E75.5 Other lipid storage disorders
0.000 0.964 0.036
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.964 0.036
E75.3 Sphingolipidosis, unspecified
0.000 0.964 0.036
E75.2 Other sphingolipidosis
0.000 0.964 0.036
E75.1 Other gangliosidosis
0.000 0.964 0.036
E75.0 GM2 gangliosidosis
0.000 0.964 0.036
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.964 0.036
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.964 0.036
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.964 0.036
E76.2 Other mucopolysaccharidoses
0.000 0.964 0.036
E76.1 Mucopolysaccharidosis, type II
0.000 0.964 0.036
E76.0 Mucopolysaccharidosis, type I
0.000 0.964 0.036
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.964 0.036
E77.8 Other disorders of glycoprotein metabolism
0.000 0.964 0.036
E77.1 Defects in glycoprotein degradation
0.000 0.964 0.036
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.964 0.036
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.964 0.036
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.964 0.036
E79.1 Lesch-Nyhan syndrome
0.000 0.964 0.036
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.964 0.036
E84.9 Cystic fibrosis, unspecified
0.000 0.964 0.036
E84.8 Cystic fibrosis with other manifestations
0.000 0.964 0.036
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.964 0.036
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.964 0.036
E88.9 Metabolic disorder, unspecified
0.000 0.964 0.035
E88.8 Other specified metabolic disorders
0.000 0.964 0.035
E88.3 Tumour lysis syndrome
0.000 0.964 0.035
E88.2 Lipomatosis, not elsewhere classified
0.000 0.964 0.035
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.964 0.035
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.965 0.035
E85.4 Organ-limited amyloidosis
0.000 0.966 0.034
E85.8 Other amyloidosis
0.000 0.967 0.033
E85.3 Secondary systemic amyloidosis
0.000 0.967 0.033
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.967 0.033
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.967 0.033
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.967 0.033
I77 Other disorders of arteries and arterioles
0.000 0.967 0.033
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.968 0.032
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.968 0.032
I77.1 Stricture of artery
0.000 0.970 0.030
I71 Aortic aneurysm and dissection
0.000 0.970 0.030
I77.6 Arteritis, unspecified
0.000 0.971 0.029
E85.9 Amyloidosis, unspecified
0.000 0.972 0.028
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.972 0.028
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.973 0.027
I72 Other aneurysm
0.000 0.973 0.027
I77.8 Other specified disorders of arteries and arterioles
0.000 0.973 0.027
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.973 0.027
E80.5 Crigler-Najjar syndrome
0.000 0.973 0.027
E80.3 Defects of catalase and peroxydase
0.000 0.973 0.027
E80.2 Other porphyria
0.000 0.973 0.027
E80.1 Porphyria cutanea tarda
0.000 0.973 0.027
E80.0 Hereditary erythropoietic porphyria
0.000 0.973 0.027
Chapter IX Diseases of the circulatory system
0.000 0.973 0.027
E83.3 Disorders of phosphorus metabolism
0.000 0.974 0.026
I70 Atherosclerosis
0.000 0.974 0.026
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.975 0.025
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.975 0.025
I72.4 Aneurysm of artery of lower extremity
0.000 0.976 0.024
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.976 0.024
I77.5 Necrosis of artery
0.000 0.976 0.024
I77.4 Coeliac artery compression syndrome
0.000 0.976 0.024
I77.3 Arterial fibromuscular dysplasia
0.000 0.976 0.024
I77.2 Rupture of artery
0.000 0.976 0.024
E80.6 Other disorders of bilirubin metabolism
0.000 0.976 0.023
I71.0 Dissection of aorta [any part]
0.000 0.976 0.023
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.977 0.023
E89.2 Postprocedural hypoparathyroidism
0.000 0.977 0.023
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.977 0.023
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.977 0.023
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.977 0.023
E89.5 Postprocedural testicular hypofunction
0.000 0.977 0.023
E89.4 Postprocedural ovarian failure
0.000 0.977 0.023
E89.1 Postprocedural hypoinsulinaemia
0.000 0.977 0.023
I72.3 Aneurysm of iliac artery
0.000 0.978 0.022
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.978 0.022
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.978 0.022
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.978 0.022
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.978 0.022
E89.3 Postprocedural hypopituitarism
0.000 0.978 0.021
I78 Diseases of capillaries
0.000 0.978 0.022
I74 Arterial embolism and thrombosis
0.000 0.978 0.022
I77.0 Arteriovenous fistula, acquired
0.000 0.979 0.021
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.979 0.021
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.979 0.021
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.980 0.020
I79.1 Aortitis in diseases classified elsewhere
0.000 0.980 0.020
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.980 0.020
I70.0 Atherosclerosis of aorta
0.000 0.980 0.020
I72.8 Aneurysm of other specified arteries
0.000 0.980 0.020
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.980 0.019
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.980 0.019
I72.1 Aneurysm of artery of upper extremity
0.000 0.980 0.019
I00-I02 Acute rheumatic fever
0.000 0.981 0.019
E80.4 Gilbert's syndrome
0.000 0.981 0.019
I72.2 Aneurysm of renal artery
0.000 0.981 0.019
I70.9 Generalised and unspecified atherosclerosis
0.000 0.981 0.019
I70.8 Atherosclerosis of other arteries
0.000 0.981 0.019
I70.1 Atherosclerosis of renal artery
0.000 0.981 0.019
I72.9 Aneurysm of unspecified site
0.000 0.981 0.019
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.982 0.018
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.982 0.018
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.983 0.017
I74.5 Embolism and thrombosis of iliac artery
0.000 0.983 0.017
I78.9 Disease of capillaries, unspecified
0.000 0.984 0.016
I74.8 Embolism and thrombosis of other arteries
0.000 0.984 0.016
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.984 0.016
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.984 0.016
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.984 0.016
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.985 0.015
I78.8 Other diseases of capillaries
0.000 0.985 0.015
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.985 0.015
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.985 0.015
I72.0 Aneurysm of carotid artery
0.000 0.985 0.014
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.986 0.014
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.986 0.014
I02 Rheumatic chorea
0.000 0.986 0.014
I01 Rheumatic fever with heart involvement
0.000 0.986 0.014
I00 Rheumatic fever without mention of heart involvement
0.000 0.986 0.014
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.986 0.014
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.986 0.014
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.986 0.014
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.986 0.014
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.986 0.014
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.986 0.014
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.986 0.014
I97.1 Other functional disturbances following cardiac surgery
0.000 0.987 0.013
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.988 0.012
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.988 0.012
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.001 0.988 0.011
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.988 0.012
R16.1 Splenomegaly, not elsewhere classified
0.012 0.988 0.000
N39.4 Other specified urinary incontinence
0.000 0.989 0.011
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.989 0.011
I97.0 Postcardiotomy syndrome
0.000 0.989 0.011
I05-I09 Chronic rheumatic heart diseases
0.000 0.989 0.011
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.990 0.010
I01.8 Other acute rheumatic heart disease
0.000 0.990 0.010
I01.2 Acute rheumatic myocarditis
0.000 0.990 0.010
I01.1 Acute rheumatic endocarditis
0.000 0.990 0.010
I01.0 Acute rheumatic pericarditis
0.000 0.990 0.010
I02.9 Rheumatic chorea without heart involvement
0.000 0.990 0.010
I02.0 Rheumatic chorea with heart involvement
0.000 0.990 0.010
K08.3 Retained dental root
0.000 0.990 0.010
I99 Other and unspecified disorders of circulatory system
0.000 0.990 0.010
H04.5 Stenosis and insufficiency of lachrymal passages
0.000 0.990 0.010
C67 Malignant neoplasm of bladder
0.010 0.990 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.990 0.010
I78.1 Naevus, nonneoplastic
0.000 0.990 0.010
C67.1 Dome of bladder
0.009 0.991 0.000
I73 Other peripheral vascular diseases
0.000 0.991 0.009
E83.5 Disorders of calcium metabolism
0.000 0.991 0.009
C67.6 Ureteric orifice
0.009 0.991 0.000
C67.4 Posterior wall of bladder
0.009 0.991 0.000
C67.2 Lateral wall of bladder
0.009 0.991 0.000
I28 Other diseases of pulmonary vessels
0.001 0.991 0.008
C67.9 Bladder, unspecified
0.009 0.991 0.000
H04.2 Epiphora
0.000 0.991 0.009
E89.0 Postprocedural hypothyroidism
0.000 0.992 0.008
I06 Rheumatic aortic valve diseases
0.000 0.992 0.008
H04 Disorders of lachrymal system
0.000 0.992 0.008
I26 Pulmonary embolism
0.003 0.992 0.005
C67.0 Trigone of bladder
0.008 0.992 0.000
K08 Other disorders of teeth and supporting structures
0.000 0.992 0.008
K08.8 Other specified disorders of teeth and supporting structures
0.000 0.992 0.008
I09 Other rheumatic heart diseases
0.000 0.992 0.008
C67.8 Overlapping lesion of bladder
0.008 0.992 0.000
C67.3 Anterior wall of bladder
0.007 0.993 0.000
C67.7 Urachus
0.007 0.993 0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.993 0.007
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.993 0.007
I98.0 Cardiovascular syphilis
0.000 0.993 0.007
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.993 0.007
C67.5 Bladder neck
0.007 0.993 0.000
I08 Multiple valve diseases
0.000 0.993 0.007
I73.8 Other specified peripheral vascular diseases
0.000 0.993 0.007
I28.9 Disease of pulmonary vessels, unspecified
0.001 0.993 0.006
I28.1 Aneurysm of pulmonary artery
0.001 0.993 0.006
I28.0 Arteriovenous fistula of pulmonary vessels
0.001 0.993 0.006
H04.8 Other disorders of lachrymal system
0.000 0.993 0.006
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.006 0.993 0.000
I27 Other pulmonary heart diseases
0.000 0.994 0.006
M13.99 Arthritis, unspecified (Site unspecified)
0.000 0.994 0.006
H04.3 Acute and unspecified inflammation of lachrymal passages
0.000 0.994 0.006
I28.8 Other specified diseases of pulmonary vessels
0.001 0.994 0.006
K08.2 Atrophy of edentulous alveolar ridge
0.000 0.994 0.006
I05 Rheumatic mitral valve diseases
0.000 0.994 0.006
I08.8 Other multiple valve diseases
0.000 0.994 0.006
I07 Rheumatic tricuspid valve diseases
0.000 0.994 0.006
H04.9 Disorder of lachrymal system, unspecified
0.000 0.994 0.006
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.994 0.006
I06.8 Other rheumatic aortic valve diseases
0.000 0.994 0.006
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.994 0.006
I06.1 Rheumatic aortic insufficiency
0.000 0.994 0.006
I06.0 Rheumatic aortic stenosis
0.000 0.994 0.006
H04.6 Other changes in lachrymal passages
0.000 0.994 0.006
H04.0 Dacryoadenitis
0.000 0.994 0.006
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.002 0.994 0.004
K08.9 Disorder of teeth and supporting structures, unspecified
0.000 0.994 0.006
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.000 0.994 0.006
K08.0 Exfoliation of teeth due to systemic causes
0.000 0.994 0.006
I09.8 Other specified rheumatic heart diseases
0.000 0.994 0.006
I09.2 Chronic rheumatic pericarditis
0.000 0.994 0.006
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.994 0.006
I09.0 Rheumatic myocarditis
0.000 0.994 0.006
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.994 0.006
H04.4 Chronic inflammation of lachrymal passages
0.000 0.994 0.006
I51.9 Heart disease, unspecified
0.000 0.994 0.006
I09.9 Rheumatic heart disease, unspecified
0.000 0.994 0.005
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.994 0.005
H04.1 Other disorders of lachrymal gland
0.000 0.995 0.005
I08.9 Multiple valve disease, unspecified
0.000 0.995 0.005
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.995 0.005
I73.9 Peripheral vascular disease, unspecified
0.000 0.995 0.005
I27.8 Other specified pulmonary heart diseases
0.000 0.995 0.005
I08.0 Disorders of both mitral and aortic valves
0.000 0.995 0.005
I27.1 Kyphoscoliotic heart disease
0.000 0.995 0.005
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.995 0.005
E28.3 Primary ovarian failure
0.005 0.995 0.000
I05.1 Rheumatic mitral insufficiency
0.000 0.995 0.005
I10-I15 Hypertensive diseases
0.000 0.995 0.005
I05.8 Other mitral valve diseases
0.000 0.995 0.004
I05.2 Mitral stenosis with insufficiency
0.000 0.995 0.005
I07.9 Tricuspid valve disease, unspecified
0.000 0.995 0.004
I07.8 Other tricuspid valve diseases
0.000 0.995 0.004
I07.2 Tricuspid stenosis with insufficiency
0.000 0.995 0.004
I07.0 Tricuspid stenosis
0.000 0.995 0.004
E28 Ovarian dysfunction
0.005 0.995 0.000
O14.9 Preeclampsia, unspecified
0.005 0.995 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.005 0.995 0.000
E61.1 Iron deficiency
0.000 0.996 0.004
I27.9 Pulmonary heart disease, unspecified
0.000 0.996 0.004
I27.0 Primary pulmonary hypertension
0.000 0.996 0.004
E28.2 Polycystic ovarian syndrome
0.004 0.996 0.000
E23.2 Diabetes insipidus
0.004 0.996 0.000
E23 Hypofunction and other disorders of pituitary gland
0.004 0.996 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.996 0.004
E20-E35 Disorders of other endocrine glands
0.004 0.996 0.000
H52.1 Myopia
0.004 0.996 0.000
I05.9 Mitral valve disease, unspecified
0.000 0.996 0.004
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.996 0.004
I27.2 Other secondary pulmonary hypertension
0.000 0.996 0.004
I51 Complications and ill-defined descriptions of heart disease
0.000 0.996 0.004
E23.7 Disorder of pituitary gland, unspecified
0.004 0.996 0.000
E34 Other endocrine disorders
0.004 0.996 0.000
I05.0 Mitral stenosis
0.000 0.996 0.003
I51.6 Cardiovascular disease, unspecified
0.000 0.996 0.004
E61 Deficiency of other nutrient elements
0.000 0.996 0.004
I13 Hypertensive heart and renal disease
0.000 0.996 0.004
E34.0 Carcinoid syndrome
0.004 0.996 0.000
I11 Hypertensive heart disease
0.000 0.996 0.003
W19.4 Street and highway
0.004 0.996 0.000
E28.9 Ovarian dysfunction, unspecified
0.003 0.996 0.000
E28.8 Other ovarian dysfunction
0.003 0.996 0.000
E28.1 Androgen excess
0.003 0.996 0.000
E28.0 Oestrogen excess
0.003 0.996 0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified
0.003 0.996 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.997 0.003
E40-E46 Malnutrition
0.000 0.997 0.003
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.997 0.003
L30.9 Dermatitis, unspecified
0.003 0.997 0.000
E29 Testicular dysfunction
0.003 0.997 0.000
E50-E64 Other nutritional deficiencies
0.000 0.997 0.003
E23.6 Other disorders of pituitary gland
0.003 0.997 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.003 0.997 0.000
E23.1 Drug-induced hypopituitarism
0.003 0.997 0.000
I51.0 Cardiac septal defect, acquired
0.000 0.997 0.003
I15 Secondary hypertension
0.000 0.997 0.003
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.997 0.003
R16.0 Hepatomegaly, not elsewhere classified
0.003 0.997 0.000
E27 Other disorders of adrenal gland
0.003 0.997 0.000
E34.9 Endocrine disorder, unspecified
0.003 0.997 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.997 0.003
E35 Disorders of endocrine glands in diseases classified elsewhere
0.003 0.997 0.000
E32 Diseases of thymus
0.003 0.997 0.000
E31 Polyglandular dysfunction
0.003 0.997 0.000
E30 Disorders of puberty, not elsewhere classified
0.003 0.997 0.000
E25 Adrenogenital disorders
0.003 0.997 0.000
E22 Hyperfunction of pituitary gland
0.003 0.997 0.000
E87.3 Alkalosis
0.000 0.997 0.003
I51.7 Cardiomegaly
0.000 0.997 0.003
E24 Cushing's syndrome
0.003 0.997 0.000
E87.4 Mixed disorder of acid-base balance
0.000 0.997 0.003
I51.5 Myocardial degeneration
0.000 0.997 0.003
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.997 0.003
E20 Hypoparathyroidism
0.003 0.997 0.000
N36.8 Other specified disorders of urethra
0.003 0.997 0.000
E23.0 Hypopituitarism
0.003 0.997 0.000
E27.8 Other specified disorders of adrenal gland
0.003 0.997 0.000
E26 Hyperaldosteronism
0.003 0.997 0.000
E34.5 Androgen resistance syndrome
0.003 0.997 0.000
E34.4 Constitutional tall stature
0.003 0.997 0.000
E34.3 Short stature, not elsewhere classified
0.003 0.997 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.003 0.997 0.000
E34.1 Other hypersecretion of intestinal hormones
0.003 0.997 0.000
C64-C68 Malignant neoplasms of urinary tract
0.003 0.997 0.000
E11.0 With coma
0.000 0.997 0.003
E61.9 Deficiency of nutrient element, unspecified
0.000 0.997 0.003
E61.8 Deficiency of other specified nutrient elements
0.000 0.997 0.003
E61.7 Deficiency of multiple nutrient elements
0.000 0.997 0.003
E61.6 Vanadium deficiency
0.000 0.997 0.003
E61.5 Molybdenum deficiency
0.000 0.997 0.003
E61.4 Chromium deficiency
0.000 0.997 0.003
E61.3 Manganese deficiency
0.000 0.997 0.003
E61.2 Magnesium deficiency
0.000 0.997 0.003
E61.0 Copper deficiency
0.000 0.997 0.003
I51.4 Myocarditis, unspecified
0.000 0.997 0.003
E11 Non-insulin-dependent diabetes mellitus
0.000 0.997 0.003
E11.2 With renal complications
0.000 0.997 0.003
E34.8 Other specified endocrine disorders
0.003 0.997 0.000
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.997 0.003
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.997 0.003
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.997 0.003
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.997 0.003
E46 Unspecified protein-energy malnutrition
0.000 0.997 0.003
E29.1 Testicular hypofunction
0.003 0.997 0.000
N36.2 Urethral caruncle
0.003 0.997 0.000
H02.0 Entropion and trichiasis of eyelid
0.003 0.997 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.997 0.003
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.997 0.003
E45 Retarded development following protein-energy malnutrition
0.000 0.997 0.003
E43 Unspecified severe protein-energy malnutrition
0.000 0.997 0.003
E42 Marasmic kwashiorkor
0.000 0.997 0.003
E41 Nutritional marasmus
0.000 0.997 0.003
E40 Kwashiorkor
0.000 0.997 0.003
E29.9 Testicular dysfunction, unspecified
0.002 0.997 0.000
E29.8 Other testicular dysfunction
0.002 0.997 0.000
E29.0 Testicular hyperfunction
0.002 0.997 0.000
I07.1 Tricuspid insufficiency
0.000 0.997 0.002
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.997 0.002
E63 Other nutritional deficiencies
0.000 0.997 0.002
E56 Other vitamin deficiencies
0.000 0.997 0.002
E51 Thiamine deficiency
0.000 0.997 0.002
E50 Vitamin A deficiency
0.000 0.997 0.002
E60 Dietary zinc deficiency
0.000 0.997 0.002
E59 Dietary selenium deficiency
0.000 0.997 0.002
E58 Dietary calcium deficiency
0.000 0.997 0.002
E54 Ascorbic acid deficiency
0.000 0.997 0.002
E52 Niacin deficiency [pellagra]
0.000 0.997 0.002
E87.5 Hyperkalaemia
0.000 0.997 0.003
E11.1 With ketoacidosis
0.000 0.997 0.003
O70.1 Second degree perineal laceration during delivery
0.003 0.997 0.000
S51.0 Open wound of elbow
0.003 0.997 0.000
I15.1 Hypertension secondary to other renal disorders
0.000 0.997 0.002
E22.1 Hyperprolactinaemia
0.002 0.997 0.000
H52.2 Astigmatism
0.003 0.997 0.000
E22.0 Acromegaly and pituitary gigantism
0.002 0.997 0.000
E27.9 Disorder of adrenal gland, unspecified
0.002 0.997 0.000
O03.9 Complete or unspecified, without complication
0.003 0.997 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.003 0.997 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.997 0.003
I15.8 Other secondary hypertension
0.000 0.997 0.002
I15.2 Hypertension secondary to endocrine disorders
0.000 0.997 0.002
I15.0 Renovascular hypertension
0.000 0.997 0.002
W19.1 Residential institution
0.003 0.997 0.000
E27.5 Adrenomedullary hyperfunction
0.002 0.997 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.002 0.997 0.000
E27.1 Primary adrenocortical insufficiency
0.002 0.997 0.000
E27.0 Other adrenocortical overactivity
0.002 0.997 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.000 0.997 0.003
E16 Other disorders of pancreatic internal secretion
0.000 0.997 0.002
E15 Nondiabetic hypoglycaemic coma
0.000 0.997 0.002
H52 Disorders of refraction and accommodation
0.003 0.997 0.000
E25.9 Adrenogenital disorder, unspecified
0.002 0.997 0.000
E25.8 Other adrenogenital disorders
0.002 0.997 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.002 0.997 0.000
E30.9 Disorder of puberty, unspecified
0.002 0.997 0.000
E30.8 Other disorders of puberty
0.002 0.997 0.000
E30.1 Precocious puberty
0.002 0.997 0.000
E30.0 Delayed puberty
0.002 0.997 0.000
E31.9 Polyglandular dysfunction, unspecified
0.002 0.997 0.000
E31.8 Other polyglandular dysfunction
0.002 0.997 0.000
E31.1 Polyglandular hyperfunction
0.002 0.997 0.000
E31.0 Autoimmune polyglandular failure
0.002 0.997 0.000
E32.9 Disease of thymus, unspecified
0.002 0.997 0.000
E32.8 Other diseases of thymus
0.002 0.997 0.000
E32.1 Abscess of thymus
0.002 0.997 0.000
E32.0 Persistent hyperplasia of thymus
0.002 0.997 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.002 0.997 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.002 0.997 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.002 0.997 0.000
O70.9 Perineal laceration during delivery, unspecified
0.003 0.997 0.000
S82.10 Fracture of upper end of tibia (closed)
0.003 0.997 0.000
E11.5 With peripheral circulatory complications
0.000 0.997 0.003
W19 Unspecified fall
0.003 0.997 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.002 0.997 0.000
E22.8 Other hyperfunction of pituitary gland
0.002 0.997 0.000
E24.8 Other Cushing's syndrome
0.002 0.997 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.002 0.997 0.000
E24.3 Ectopic ACTH syndrome
0.002 0.997 0.000
E24.2 Drug-induced Cushing's syndrome
0.002 0.997 0.000
E24.1 Nelson's syndrome
0.002 0.997 0.000
E24.0 Pituitary-dependent Cushing's disease
0.002 0.997 0.000
E20.8 Other hypoparathyroidism
0.002 0.998 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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