TreeWAS – Variant ID: rs4395908

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S00.1 Contusion of eyelid and periocular area	0.000	0.956	0.044
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.028	0.972	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.026	0.974	0.000
F31 Bipolar affective disorder	0.023	0.977	0.000
I08.0 Disorders of both mitral and aortic valves	0.000	0.977	0.023
F31.7 Bipolar affective disorder, currently in remission	0.019	0.981	0.000
F31.9 Bipolar affective disorder, unspecified	0.018	0.982	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.017	0.983	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.015	0.985	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.015	0.985	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.015	0.985	0.000
F31.8 Other bipolar affective disorders	0.014	0.986	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.000	0.986	0.014
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.014	0.986	0.000
K70.9 Alcoholic liver disease, unspecified	0.009	0.991	0.000
K70 Alcoholic liver disease	0.009	0.991	0.000
S00 Superficial injury of head	0.000	0.992	0.008
K70.1 Alcoholic hepatitis	0.008	0.992	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.000	0.992	0.008
S00.5 Superficial injury of lip and oral cavity	0.000	0.992	0.008
K70.3 Alcoholic cirrhosis of liver	0.008	0.992	0.000
I08 Multiple valve diseases	0.000	0.993	0.007
S00.3 Superficial injury of nose	0.000	0.993	0.007
K70.2 Alcoholic fibrosis and sclerosis of liver	0.007	0.993	0.000
H53.0 Amblyopia ex anopsia	0.000	0.993	0.007
C20 Malignant neoplasm of rectum	0.000	0.993	0.007
I08.8 Other multiple valve diseases	0.000	0.993	0.007
K70.4 Alcoholic hepatic failure	0.007	0.993	0.000
Z88.7 Personal history of allergy to serum and vaccine	0.000	0.993	0.007
K70.0 Alcoholic fatty liver	0.006	0.993	0.000
M66.06 Rupture of popliteal cyst-Lower leg	0.006	0.994	0.000
M62.88 Other specified disorders of muscle (Other)	0.006	0.994	0.000
I08.9 Multiple valve disease, unspecified	0.000	0.994	0.006
M62.89 Other specified disorders of muscle (Site unspecified)	0.005	0.995	0.000
S00.4 Superficial injury of ear	0.000	0.995	0.005
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.005	0.995	0.000
M62.8 Other specified disorders of muscle	0.005	0.995	0.000
I07.1 Tricuspid insufficiency	0.000	0.995	0.005
M62.86 Other specified disorders of muscle (Lower leg)	0.005	0.995	0.000
I07 Rheumatic tricuspid valve diseases	0.000	0.995	0.005
I05-I09 Chronic rheumatic heart diseases	0.000	0.995	0.005
S00.7 Multiple superficial injuries of head	0.000	0.996	0.004
M62.84 Other specified disorders of muscle (Hand)	0.004	0.996	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
M62.83 Other specified disorders of muscle (Forearm)	0.004	0.996	0.000
M54.57 Low back pain (Lumbosacral region)	0.004	0.996	0.000
Y42.7 Androgens and anabolic congeners	0.004	0.996	0.000
H50.0 Convergent concomitant strabismus	0.000	0.996	0.004
M62.87 Other specified disorders of muscle (Ankle and foot)	0.004	0.996	0.000
I09 Other rheumatic heart diseases	0.000	0.996	0.004
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.996	0.004
Q21.1 Atrial septal defect	0.004	0.996	0.000
I05.1 Rheumatic mitral insufficiency	0.000	0.996	0.004
I07.9 Tricuspid valve disease, unspecified	0.000	0.996	0.003
I07.8 Other tricuspid valve diseases	0.000	0.996	0.003
I07.2 Tricuspid stenosis with insufficiency	0.000	0.996	0.003
I07.0 Tricuspid stenosis	0.000	0.996	0.003
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.004	0.996	0.000
Z95.0 Presence of cardiac pacemaker	0.000	0.996	0.004
S00.0 Superficial injury of scalp	0.000	0.996	0.003
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.996	0.003
C71.0 Cerebrum, except lobes and ventricles	0.003	0.997	0.000
I05 Rheumatic mitral valve diseases	0.000	0.997	0.003
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.003	0.997	0.000
L98.0 Pyogenic granuloma	0.000	0.997	0.003
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
C71.3 Parietal lobe	0.003	0.997	0.000
C71.1 Frontal lobe	0.003	0.997	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
M62.82 Other specified disorders of muscle (Upper arm)	0.003	0.997	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
Z80.4 Family history of malignant neoplasm of genital organs	0.003	0.997	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.003	0.997	0.000
Y42.5 Other oestrogens and progestogens	0.003	0.997	0.000
M66.0 Rupture of popliteal cyst	0.003	0.997	0.000
T78.4 Allergy, unspecified	0.000	0.997	0.003
Y42.2 Antithyroid drugs	0.003	0.997	0.000
I09.9 Rheumatic heart disease, unspecified	0.000	0.997	0.003
C71 Malignant neoplasm of brain	0.003	0.997	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
D26.0 Cervix uteri	0.003	0.997	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
I09.8 Other specified rheumatic heart diseases	0.000	0.997	0.003
I09.2 Chronic rheumatic pericarditis	0.000	0.997	0.003
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.997	0.003
I09.0 Rheumatic myocarditis	0.000	0.997	0.003
J30.3 Other allergic rhinitis	0.000	0.997	0.003
Y42.0 Glucocorticoids and synthetic analogs	0.003	0.997	0.000
K57.1 Diverticular disease of small intestine without perforation or abscess	0.003	0.997	0.000
C71.9 Brain, unspecified	0.003	0.997	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.003	0.997	0.000
I06 Rheumatic aortic valve diseases	0.000	0.997	0.003
Y42.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
I05.8 Other mitral valve diseases	0.000	0.997	0.003
S52.20 Fracture of shaft of ulna (closed)	0.003	0.997	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.000	0.997	0.003
Q21 Congenital malformations of cardiac septa	0.003	0.997	0.000
C71.4 Occipital lobe	0.003	0.997	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
C83.1 Small cleaved cell (diffuse)	0.000	0.997	0.003
I15.1 Hypertension secondary to other renal disorders	0.000	0.997	0.003
T78.2 Anaphylactic shock, unspecified	0.000	0.997	0.003
Y42.1 Thyroid hormones and substitutes	0.003	0.997	0.000
C71.7 Brain stem	0.003	0.997	0.000
M66.09 Rupture of popliteal cyst-Site unspec	0.002	0.997	0.000
M66.08 Rupture of popliteal cyst-Other	0.002	0.997	0.000
M66.07 Rupture of popliteal cyst-Ankle/foot	0.002	0.997	0.000
M66.05 Rupture of popliteal cyst-Pelvic/thigh	0.002	0.997	0.000
M66.04 Rupture of popliteal cyst-Hand	0.002	0.997	0.000
M66.03 Rupture of popliteal cyst-Forearm	0.002	0.997	0.000
M66.02 Rupture of popliteal cyst-Upper arm	0.002	0.997	0.000
M66.01 Rupture of popliteal cyst-Shldr region	0.002	0.997	0.000
M66.00 Rupture of popliteal cyst-Mult sites	0.002	0.997	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.002	0.997	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
I82.8 Embolism and thrombosis of other specified veins	0.003	0.997	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.002
Q21.0 Ventricular septal defect	0.002	0.997	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.002	0.998	0.000
Q21.8 Other congenital malformations of cardiac septa	0.002	0.998	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.998	0.002
C71.6 Cerebellum	0.002	0.998	0.000
C71.5 Cerebral ventricle	0.002	0.998	0.000
Y42.4 Oral contraceptives	0.002	0.998	0.000
I06.8 Other rheumatic aortic valve diseases	0.000	0.998	0.002
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.998	0.002
I05.0 Mitral stenosis	0.000	0.998	0.002
F05.0 Delirium not superimposed on dementia, so described	0.000	0.998	0.002
T78 Adverse effects, not elsewhere classified	0.000	0.998	0.002
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.000	0.998	0.002
I15.9 Seconday hypertension, unspecified	0.000	0.998	0.002
F05.9 Delirium, unspecified	0.000	0.998	0.002
Q21.4 Aortopulmonary septal defect	0.002	0.998	0.000
Q21.2 Atrioventricular septal defect	0.002	0.998	0.000
C83.0 Small cell (diffuse)	0.000	0.998	0.002
I06.1 Rheumatic aortic insufficiency	0.000	0.998	0.002
M21.27 Flexion deformity (Ankle and foot)	0.000	0.998	0.002
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.998	0.002
I82 Other venous embolism and thrombosis	0.002	0.998	0.000
C83.7 Burkitt's tumour	0.000	0.998	0.002
I05.2 Mitral stenosis with insufficiency	0.000	0.998	0.002
Q18.1 Preauricular sinus and cyst	0.002	0.998	0.000
F05.1 Delirium superimposed on dementia	0.000	0.998	0.002
Q39.4 Oesophageal web	0.000	0.998	0.002
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.998	0.002
G93.8 Other specified disorders of brain	0.002	0.998	0.000
I06.0 Rheumatic aortic stenosis	0.000	0.998	0.002
Q24.8 Other specified congenital malformations of heart	0.002	0.998	0.000
Q27.3 Peripheral arteriovenous malformation	0.002	0.998	0.000
I05.9 Mitral valve disease, unspecified	0.000	0.998	0.002
M21.6 Other acquired deformities of ankle and foot	0.000	0.998	0.002
C83.5 Lymphoblastic (diffuse)	0.000	0.998	0.002
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.000	0.998	0.002
D35.1 Parathyroid gland	0.000	0.998	0.002
C83.6 Undifferentiated (diffuse)	0.000	0.998	0.002
C83.4 Immunoblastic (diffuse)	0.000	0.998	0.002
C83.2 Mixed small and large cell (diffuse)	0.000	0.998	0.002
M21.1 Varus deformity, not elsewhere classified	0.000	0.998	0.002
F05 Delirium, not induced by alcohol and other psychoactive substances	0.000	0.998	0.002
Q27 Other congenital malformations of peripheral vascular system	0.002	0.998	0.000
Q24 Other congenital malformations of heart	0.002	0.998	0.000
C83.3 Large cell (diffuse)	0.000	0.998	0.002
I82.3 Embolism and thrombosis of renal vein	0.002	0.998	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.002	0.998	0.000
M21.2 Flexion deformity	0.000	0.998	0.002
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.998	0.002
G93.0 Cerebral cysts	0.000	0.998	0.002
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.998	0.002
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.000	0.998	0.002
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.000	0.998	0.002
Q21.3 Tetralogy of Fallot	0.002	0.998	0.000
M21 Other acquired deformities of limbs	0.000	0.998	0.002
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.998	0.002
O26.8 Other specified pregnancy-related conditions	0.000	0.998	0.002
O48 Prolonged pregnancy	0.002	0.998	0.000
I15 Secondary hypertension	0.000	0.998	0.002
Q25 Congenital malformations of great arteries	0.002	0.998	0.000
C71.8 Overlapping lesion of brain	0.002	0.998	0.000
I82.0 Budd-Chiari syndrome	0.002	0.998	0.000
J04.0 Acute laryngitis	0.000	0.998	0.002
I82.1 Thrombophlebitis migrans	0.002	0.998	0.000
M21.3 Wrist or foot drop (acquired)	0.000	0.998	0.002
N02.8 Other	0.002	0.998	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.002	0.998	0.000
M21.7 Unequal limb length (acquired)	0.000	0.998	0.002
N71.9 Inflammatory disease of uterus, unspecified	0.002	0.998	0.000
Q25.6 Stenosis of pulmonary artery	0.002	0.998	0.000
R10.0 Acute abdomen	0.002	0.998	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.000	0.998	0.002
S02.00 Fracture of vault of skull (closed)	0.002	0.998	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.998	0.002
Q28.2 Arteriovenous malformation of cerebral vessels	0.000	0.998	0.002
Z75.3 Unavailability and inaccessibility of health-care facilities	0.000	0.998	0.002
G62.9 Polyneuropathy, unspecified	0.002	0.998	0.000
K61.0 Anal abscess	0.002	0.998	0.000
S69.9 Unspecified injury of wrist and hand	0.002	0.998	0.000
T78.8 Other adverse effects, not elsewhere classified	0.000	0.998	0.002
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.000	0.998	0.002
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.000	0.998	0.002
M21.68 Other acquired deformities of ankle and foot-Other	0.000	0.998	0.002
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.000	0.998	0.002
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.000	0.998	0.002
M21.64 Other acquired deformities of ankle and foot-Hand	0.000	0.998	0.002
M21.63 Other acquired deformities of ankle and foot-Forearm	0.000	0.998	0.002
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.000	0.998	0.002
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.000	0.998	0.002
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.000	0.998	0.002
H54.7 Unspecified visual loss	0.002	0.998	0.000
M21.9 Acquired deformity of limb, unspecified	0.000	0.998	0.002
Q24.4 Congenital subaortic stenosis	0.002	0.998	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.002	0.998	0.000
S79.9 Unspecified injury of hip and thigh	0.002	0.998	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.998	0.002
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.998	0.002
Q25.7 Other congenital malformations of pulmonary artery	0.002	0.998	0.000
Q43.8 Other specified congenital malformations of intestine	0.000	0.998	0.002
T78.3 Angioneurotic oedema	0.000	0.998	0.002
Q26 Congenital malformations of great veins	0.002	0.998	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.000	0.998	0.002
M21.18 Varus deformity, not elsewhere classified (Other)	0.000	0.998	0.002
M21.14 Varus deformity, not elsewhere classified (Hand)	0.000	0.998	0.002
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.000	0.998	0.002
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.000	0.998	0.002
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.000	0.998	0.002
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.000	0.998	0.002
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.000	0.998	0.002
E34.9 Endocrine disorder, unspecified	0.002	0.998	0.000
J01.9 Acute sinusitis, unspecified	0.000	0.998	0.002
Q24.6 Congenital heart block	0.002	0.998	0.000
Q24.5 Malformation of coronary vessels	0.002	0.998	0.000
Q24.3 Pulmonary infundibular stenosis	0.002	0.998	0.000
Q24.2 Cor triatriatum	0.002	0.998	0.000
Q24.1 Levocardia	0.002	0.998	0.000
Q27.4 Congenital phlebectasia	0.002	0.998	0.000
Q27.2 Other congenital malformations of renal artery	0.002	0.998	0.000
Q27.1 Congenital renal artery stenosis	0.002	0.998	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.002	0.998	0.000
Z52.0 Blood donor	0.000	0.998	0.002
M21.73 Unequal limb length (acquired) (Forearm)	0.000	0.998	0.002
Q24.0 Dextrocardia	0.002	0.998	0.000
Q25.3 Stenosis of aorta	0.002	0.998	0.000
S69.8 Other specified injuries of wrist and hand	0.002	0.998	0.000
M21.29 Flexion deformity (Site unspecified)	0.000	0.998	0.002
M21.28 Flexion deformity (Other)	0.000	0.998	0.002
M21.23 Flexion deformity (Forearm)	0.000	0.998	0.002
M21.21 Flexion deformity (Shoulder region)	0.000	0.998	0.002
M21.20 Flexion deformity (Multiple sites)	0.000	0.998	0.002
C69.6 Orbit	0.002	0.998	0.000
M93.9 Osteochondropathy, unspecified	0.002	0.998	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.002	0.998	0.000
Q25.0 Patent ductus arteriosus	0.002	0.998	0.000
S01.9 Open wound of head, part unspecified	0.000	0.998	0.002
F25.2 Schizoaffective disorder, mixed type	0.002	0.998	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.002	0.998	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.000	0.998	0.002
M21.26 Flexion deformity (Lower leg)	0.000	0.998	0.002
M21.22 Flexion deformity (Upper arm)	0.000	0.998	0.002
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.000	0.998	0.001
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.000	0.998	0.001
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.000	0.998	0.001
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.000	0.998	0.001
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.000	0.998	0.001
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.000	0.998	0.001
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.000	0.998	0.001
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.000	0.998	0.001
Q20 Congenital malformations of cardiac chambers and connexions	0.002	0.998	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.001	0.998	0.000
Q25.8 Other congenital malformations of great arteries	0.001	0.998	0.000
Q25.5 Atresia of pulmonary artery	0.001	0.998	0.000
Q25.2 Atresia of aorta	0.001	0.998	0.000
T78.9 Adverse effect, unspecified	0.000	0.998	0.001
I15.0 Renovascular hypertension	0.000	0.998	0.001
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.001	0.998	0.000
Q43.3 Congenital malformations of intestinal fixation	0.000	0.998	0.002
M21.39 Wrist or foot drop (acquired)-Site unspec	0.000	0.998	0.001
M21.38 Wrist or foot drop (acquired)-Other	0.000	0.998	0.001
M21.36 Wrist or foot drop (acquired)-Lower leg	0.000	0.998	0.001
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.000	0.998	0.001
M21.34 Wrist or foot drop (acquired) (Hand)	0.000	0.998	0.001
M21.32 Wrist or foot drop (acquired)-Upper arm	0.000	0.998	0.001
M21.31 Wrist or foot drop (acquired)-Shldr region	0.000	0.998	0.001
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.000	0.998	0.001
M21.79 Unequal limb length (acquired) (Site unspecified)	0.000	0.998	0.001
M21.78 Unequal limb length (acquired)-Other	0.000	0.998	0.001
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.000	0.998	0.001
M21.74 Unequal limb length (acquired) (Hand)	0.000	0.998	0.001
M21.72 Unequal limb length (acquired) (Upper arm)	0.000	0.998	0.001
M21.71 Unequal limb length (acquired)-Shldr region	0.000	0.998	0.001
M21.70 Unequal limb length (acquired) (Multiple sites)	0.000	0.998	0.001
B01.9 Varicella without complications	0.002	0.998	0.000
I15.2 Hypertension secondary to endocrine disorders	0.000	0.998	0.001
N02 Recurrent and persistent haematuria	0.002	0.998	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.000	0.998	0.001
S82.20 Fracture of shaft of tibia (closed)	0.000	0.998	0.002
I82.2 Embolism and thrombosis of vena cava	0.001	0.998	0.000
N04.9 Unspecified	0.002	0.998	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.002	0.998	0.000
D03.5 Melanoma in situ of trunk	0.002	0.998	0.000
Q25.1 Coarctation of aorta	0.001	0.998	0.000
Q28 Other congenital malformations of circulatory system	0.001	0.998	0.001
Q43 Other congenital malformations of intestine	0.000	0.998	0.002
I15.8 Other secondary hypertension	0.000	0.998	0.001
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.000	0.998	0.001
M21.98 Acquired deformity of limb, unspecified-Other	0.000	0.998	0.001
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.000	0.998	0.001
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.000	0.998	0.001
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.000	0.998	0.001
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.000	0.998	0.001
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.000	0.998	0.001
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.000	0.998	0.001
F84.5 Asperger's syndrome	0.001	0.998	0.000
L03.2 Cellulitis of face	0.002	0.998	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.001	0.998	0.000
Q26.8 Other congenital malformations of great veins	0.001	0.998	0.000
Q26.6 Portal vein-hepatic artery fistula	0.001	0.998	0.000
Q26.5 Anomalous portal venous connexion	0.001	0.998	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.001	0.998	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.001	0.998	0.000
Q26.1 Persistent left superior vena cava	0.001	0.998	0.000
Q26.0 Congenital stenosis of vena cava	0.001	0.998	0.000
N02.9 Unspecified	0.002	0.998	0.000
N02.0 Minor glomerular abnormality	0.001	0.998	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.001	0.998	0.000
T14.4 Injury of nerve(s) of unspecified body region	0.001	0.998	0.000
T14.1 Open wound of unspecified body region	0.001	0.998	0.000
C69 Malignant neoplasm of eye and adnexa	0.001	0.998	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.001	0.998	0.000
F25 Schizoaffective disorders	0.001	0.998	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.000	0.999	0.001
M21.94 Acquired deformity of limb, unspecified (Hand)	0.000	0.999	0.001
H27.1 Dislocation of lens	0.001	0.999	0.000
N02.3 Diffuse mesangial proliferative glomerulonephritis	0.001	0.999	0.000
D03.4 Melanoma in situ of scalp and neck	0.001	0.999	0.000
F05.8 Other delirium	0.000	0.999	0.001
F25.1 Schizoaffective disorder, depressive type	0.001	0.999	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.001	0.999	0.000
N02.2 Diffuse membranous glomerulonephritis	0.001	0.999	0.000
N02.1 Focal and segmental glomerular lesions	0.001	0.999	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.001	0.999	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.001	0.999	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.001	0.999	0.000
Q20.6 Isomerism of atrial appendages	0.001	0.999	0.000
Q20.5 Discordant atrioventricular connexion	0.001	0.999	0.000
Q20.4 Double inlet ventricle	0.001	0.999	0.000
Q20.3 Discordant ventriculoarterial connexion	0.001	0.999	0.000
Q20.2 Double outlet left ventricle	0.001	0.999	0.000
Q20.1 Double outlet right ventricle	0.001	0.999	0.000
Q20.0 Common arterial trunk	0.001	0.999	0.000
Q43.1 Hirschsprung's disease	0.000	0.999	0.001
S00.8 Superficial injury of other parts of head	0.000	0.999	0.001
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.000	0.999	0.001
M62 Other disorders of muscle	0.001	0.999	0.000
Q18 Other congenital malformations of face and neck	0.001	0.999	0.000
Q39 Congenital malformations of oesophagus	0.000	0.999	0.001
S32.40 Fracture of acetabulum (closed)	0.000	0.999	0.001
G97.8 Other postprocedural disorders of nervous system	0.001	0.999	0.000
H27.0 Aphakia	0.001	0.999	0.000
H54.9 Unspecified visual impairment (binocular)	0.001	0.999	0.000
N02.7 Diffuse crescentic glomerulonephritis	0.001	0.999	0.000
N02.6 Dense deposit disease	0.001	0.999	0.000
N02.5 Diffuse mesangiocapillary glomerulonephritis	0.001	0.999	0.000
N02.4 Diffuse endocapillary proliferative glomerulonephritis	0.001	0.999	0.000
N04.0 Minor glomerular abnormality	0.001	0.999	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.000	0.999	0.001
C70 Malignant neoplasm of meninges	0.001	0.999	0.000
Q23 Congenital malformations of aortic and mitral valves	0.001	0.999	0.000
T14.6 Injury of tendons and muscles of unspecified body region	0.001	0.999	0.000
T14 Injury of unspecified body region	0.001	0.999	0.000
M21.24 Flexion deformity (Hand)	0.000	0.999	0.001
D48.1 Connective and other soft tissue	0.000	0.999	0.001
J98.5 Diseases of mediastinum, not elsewhere classified	0.001	0.999	0.000
M21.4 Flat foot [pes planus] (acquired)	0.000	0.999	0.001
Q28.9 Congenital malformation of circulatory system, unspecified	0.001	0.999	0.001
Q28.8 Other specified congenital malformations of circulatory system	0.001	0.999	0.001
Q28.1 Other malformations of precerebral vessels	0.001	0.999	0.001
Q43.7 Persistent cloaca	0.000	0.999	0.001
Q43.6 Congenital fistula of rectum and anus	0.000	0.999	0.001
Q43.5 Ectopic anus	0.000	0.999	0.001
Q43.4 Duplication of intestine	0.000	0.999	0.001
Q43.2 Other congenital functional disorders of colon	0.000	0.999	0.001
S69.7 Multiple injuries of wrist and hand	0.001	0.999	0.000
Z50.8 Care involving use of rehabilitation procedures	0.000	0.999	0.001
S69 Other and unspecified injuries of wrist and hand	0.001	0.999	0.000
S92.41 Fracture of great toe (open)	0.001	0.999	0.000
M21.0 Valgus deformity, not elsewhere classified	0.000	0.999	0.001
Q25.4 Other congenital malformations of aorta	0.001	0.999	0.000
F25.0 Schizoaffective disorder, manic type	0.001	0.999	0.000
M21.8 Other specified acquired deformities of limbs	0.000	0.999	0.001
M62.4 Contracture of muscle	0.001	0.999	0.000
N04.1 Focal and segmental glomerular lesions	0.001	0.999	0.000
Q28.3 Other malformations of cerebral vessels	0.001	0.999	0.001
Q39.9 Congenital malformation of oesophagus, unspecified	0.000	0.999	0.001
N04 Nephrotic syndrome	0.001	0.999	0.000
C69.8 Overlapping lesion of eye and adnexa	0.001	0.999	0.000
C69.5 Lachrymal gland and duct	0.001	0.999	0.000
C69.1 Cornea	0.001	0.999	0.000
C69.0 Conjunctiva	0.001	0.999	0.000
F25.9 Schizoaffective disorder, unspecified	0.001	0.999	0.000
H34.8 Other retinal vascular occlusions	0.001	0.999	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.001	0.999	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.001	0.999	0.000
Q22.6 Hypoplastic right heart syndrome	0.001	0.999	0.000
Q22.4 Congenital tricuspid stenosis	0.001	0.999	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.001	0.999	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.001	0.999	0.000
Q22.0 Pulmonary valve atresia	0.001	0.999	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.001	0.999	0.001
R34 Anuria and oliguria	0.001	0.999	0.000
M21.76 Unequal limb length (acquired) (Lower leg)	0.000	0.999	0.001
S32.10 Fracture of sacrum (closed)	0.000	0.999	0.001
C18.2 Ascending colon	0.000	0.999	0.001
F25.8 Other schizoaffective disorders	0.001	0.999	0.000
Q23.3 Congenital mitral insufficiency	0.001	0.999	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.001	0.999	0.000
C70.0 Cerebral meninges	0.001	0.999	0.000
J38.3 Other diseases of vocal cords	0.000	0.999	0.001
M32.1 Systemic lupus erythematosus with organ or system involvement	0.000	0.999	0.001
Q22.5 Ebstein's anomaly	0.001	0.999	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.001	0.999	0.000
B59 Pneumocystosis	0.001	0.999	0.000
M62.46 Contracture of muscle (Lower leg)	0.001	0.999	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.000	0.999	0.001
C70.9 Meninges, unspecified	0.001	0.999	0.000
C70.1 Spinal meninges	0.001	0.999	0.000
C71.2 Temporal lobe	0.001	0.999	0.000
E53.8 Deficiency of other specified B group vitamins	0.000	0.999	0.001
J04.1 Acute tracheitis	0.000	0.999	0.001
M62.3 Immobility syndrome (paraplegic)	0.001	0.999	0.000
M62.2 Ischaemic infarction of muscle	0.001	0.999	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.001	0.999	0.000
Q18.8 Other specified congenital malformations of face and neck	0.001	0.999	0.000
Q18.7 Microcheilia	0.001	0.999	0.000
Q18.6 Macrocheilia	0.001	0.999	0.000
Q18.5 Microstomia	0.001	0.999	0.000
Q18.4 Macrostomia	0.001	0.999	0.000
Q18.3 Webbing of neck	0.001	0.999	0.000
Q18.2 Other branchial cleft malformations	0.001	0.999	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.001	0.999	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.001	0.999	0.000
Q23.4 Hypoplastic left heart syndrome	0.001	0.999	0.000
Q23.2 Congenital mitral stenosis	0.001	0.999	0.000
Q39.8 Other congenital malformations of oesophagus	0.000	0.999	0.001
Q39.5 Congenital dilatation of oesophagus	0.000	0.999	0.001
Q39.3 Congenital stenosis and stricture of oesophagus	0.000	0.999	0.001
Q39.2 Congenital tracheooesophageal fistula without atresia	0.000	0.999	0.001
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.000	0.999	0.001
Q39.0 Atresia of oesophagus without fistula	0.000	0.999	0.001
T14.0 Superficial injury of unspecified body region	0.001	0.999	0.000
T79.7 Traumatic subcutaneous emphysema	0.000	0.999	0.001
M25.37 Other instability of joint (Ankle and foot)	0.000	0.999	0.001
C69.4 Ciliary body	0.001	0.999	0.000
T14.2 Fracture of unspecified body region	0.001	0.999	0.000
T14.8 Other injuries of unspecified body region	0.001	0.999	0.000
T14.7 Crushing injury and traumatic amputation of unspecified body region	0.001	0.999	0.000
T14.5 Injury of blood vessel(s) of unspecified body region	0.001	0.999	0.000
T14.3 Dislocation, sprain and strain of unspecified body region	0.001	0.999	0.000
Y49.5 Other antipsychotics and neuroleptics	0.001	0.999	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.000	0.999	0.001
M21.08 Valgus deformity, not elsewhere classified (Other)	0.000	0.999	0.001
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.999	0.001
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.000	0.999	0.001
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.000	0.999	0.001
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.000	0.999	0.001
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.000	0.999	0.001
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.000	0.999	0.001
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.000	0.999	0.001
M21.48 Flat foot [pes planus] (acquired)-Other	0.000	0.999	0.001
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.000	0.999	0.001
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.000	0.999	0.001
M21.44 Flat foot [pes planus] (acquired)-Hand	0.000	0.999	0.001
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.000	0.999	0.001
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.000	0.999	0.001
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.000	0.999	0.001
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.000	0.999	0.001
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.999	0.001
C69.9 Eye, unspecified	0.001	0.999	0.000
C69.3 Choroid	0.001	0.999	0.000
C69.2 Retina	0.001	0.999	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.001	0.999	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.001	0.999	0.000
T14.9 Injury, unspecified	0.001	0.999	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.000	0.999	0.001
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.000	0.999	0.001
M21.88 Other specified acquired deformities of limbs-Other	0.000	0.999	0.001
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.000	0.999	0.001
M21.84 Other specified acquired deformities of limbs (Hand)	0.000	0.999	0.001
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.000	0.999	0.001
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.000	0.999	0.001
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.000	0.999	0.001
M62.49 Contracture of muscle (Site unspecified)	0.001	0.999	0.000
M62.48 Contracture of muscle (Other)	0.001	0.999	0.000
M62.47 Contracture of muscle (Ankle and foot)	0.001	0.999	0.000
M62.45 Contracture of muscle (Pelvic region and thigh)	0.001	0.999	0.000
M62.44 Contracture of muscle (Hand)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations