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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6820069
log Bayes Factor = 17.9919
Chromosome 4   position 178,283,370  (GRCh37) Explore rs6820069 on Ensembl!
Variant rs6820069 is part of Cluster X0075

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
0.999 0.001 0.000
M70-M79 Other soft tissue disorders
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.997 0.003 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.996 0.004 0.000
M75 Shoulder lesions
0.995 0.005 0.000
Chapter XXI Factors influencing health status and contact with health services
0.991 0.009 0.000
Chapter XIV Diseases of the genitourinary system
0.985 0.015 0.000
E11.9 Without complications
0.982 0.018 0.000
N17-N19 Renal failure
0.982 0.018 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.981 0.019 0.000
S00-S09 Injuries to the head
0.977 0.023 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.974 0.026 0.000
I60-I69 Cerebrovascular diseases
0.972 0.028 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.972 0.028 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.969 0.031 0.000
Chapter V Mental and behavioural disorders
0.966 0.034 0.000
E11.3 With ophthalmic complications
0.964 0.036 0.000
N19 Unspecified renal failure
0.964 0.036 0.000
E70-E90 Metabolic disorders
0.962 0.038 0.000
S60-S69 Injuries to the wrist and hand
0.958 0.042 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.956 0.044 0.000
E14 Unspecified diabetes mellitus
0.949 0.051 0.000
S01 Open wound of head
0.949 0.051 0.000
S40-S49 Injuries to the shoulder and upper arm
0.949 0.051 0.000
N18 Chronic renal failure
0.947 0.053 0.000
N00-N08 Glomerular diseases
0.945 0.055 0.000
R79 Other abnormal findings of blood chemistry
0.945 0.055 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.944 0.056 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.943 0.057 0.000
M79.6 Pain in limb
0.943 0.057 0.000
M75.1 Rotator cuff syndrome
0.942 0.058 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.940 0.060 0.000
Chapter XX External causes of morbidity and mortality
0.939 0.061 0.000
E11.4 With neurological complications
0.936 0.064 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.936 0.064 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.933 0.067 0.000
I05-I09 Chronic rheumatic heart diseases
0.930 0.070 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.930 0.070 0.000
Z53.0 Procedure not carried out because of contraindication
0.926 0.074 0.000
M40-M43 Deforming dorsopathies
0.925 0.075 0.000
S01.8 Open wound of other parts of head
0.925 0.075 0.000
S50-S59 Injuries to the elbow and forearm
0.924 0.076 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.922 0.078 0.000
E14.9 Without complications
0.919 0.081 0.000
Chapter II Neoplasms
0.919 0.081 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.913 0.087 0.000
N20-N23 Urolithiasis
0.913 0.087 0.000
R29.6 Tendency to fall, not elsewhere classified
0.909 0.091 0.000
M75.5 Bursitis of shoulder
0.908 0.092 0.000
S61 Open wound of wrist and hand
0.908 0.092 0.000
I30-I52 Other forms of heart disease
0.901 0.099 0.000
I63 Cerebral infarction
0.900 0.100 0.000
Z53.9 Procedure not carried out, unspecified reason
0.894 0.106 0.000
N20 Calculus of kidney and ureter
0.890 0.110 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.889 0.111 0.000
F30-F39 Mood [affective] disorders
0.889 0.111 0.000
N18.3 Chronic kidney disease, stage 3
0.881 0.119 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.880 0.120 0.000
E83 Disorders of mineral metabolism
0.879 0.121 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.877 0.123 0.000
E86 Volume depletion
0.874 0.126 0.000
M05-M14 Inflammatory polyarthropathies
0.874 0.126 0.000
Z50 Care involving use of rehabilitation procedures
0.871 0.129 0.000
T43.2 Other and unspecified antidepressants
0.871 0.129 0.000
Z53.8 Procedure not carried out for other reasons
0.870 0.130 0.000
M45-M49 Spondylopathies
0.869 0.131 0.000
M80-M85 Disorders of bone density and structure
0.868 0.132 0.000
Z49 Care involving dialysis
0.866 0.134 0.000
M75.3 Calcific tendinitis of shoulder
0.864 0.136 0.000
Chapter I Certain infectious and parasitic diseases
0.860 0.140 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.859 0.141 0.000
S00 Superficial injury of head
0.858 0.142 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.856 0.144 0.000
E11.2 With renal complications
0.856 0.144 0.000
I08 Multiple valve diseases
0.855 0.145 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.854 0.146 0.000
I69 Sequelae of cerebrovascular disease
0.854 0.146 0.000
S60 Superficial injury of wrist and hand
0.850 0.150 0.000
I51 Complications and ill-defined descriptions of heart disease
0.850 0.150 0.000
Z60 Problems related to social environment
0.848 0.152 0.000
N18.4 Chronic kidney disease, stage 4
0.847 0.153 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.846 0.154 0.000
I50 Heart failure
0.846 0.154 0.000
S52 Fracture of forearm
0.842 0.158 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.841 0.159 0.000
F32 Depressive episode
0.840 0.160 0.000
Z34 Supervision of normal pregnancy
0.840 0.160 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.839 0.161 0.000
N20.0 Calculus of kidney
0.836 0.164 0.000
I67 Other cerebrovascular diseases
0.836 0.164 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.836 0.164 0.000
I61 Intracerebral haemorrhage
0.835 0.165 0.000
M43 Other deforming dorsopathies
0.834 0.166 0.000
D00-D09 In situ neoplasms
0.834 0.166 0.000
Chapter XXII Codes for special purposes
0.833 0.167 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.829 0.171 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.827 0.173 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.825 0.175 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.823 0.177 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.822 0.178 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.822 0.178 0.000
I51.8 Other ill-defined heart diseases
0.818 0.182 0.000
M79.1 Myalgia
0.816 0.184 0.000
M06 Other rheumatoid arthritis
0.814 0.186 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.813 0.187 0.000
N20.1 Calculus of ureter
0.809 0.191 0.000
N02 Recurrent and persistent haematuria
0.807 0.193 0.000
C50-C50 Malignant neoplasm of breast
0.807 0.193 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.804 0.196 0.000
Z57 Occupational exposure to risk-factors
0.804 0.196 0.000
Chapter VI Diseases of the nervous system
0.804 0.196 0.000
N18.5 Chronic kidney disease, stage 5
0.804 0.196 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.803 0.197 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.802 0.198 0.000
Z52 Donors of organs and tissues
0.802 0.198 0.000
Z51 Other medical care
0.802 0.198 0.000
B95-B98 Bacterial, viral and other infectious agents
0.800 0.200 0.000
C15-C26 Malignant neoplasms of digestive organs
0.800 0.200 0.000
M75.2 Bicipital tendinitis
0.797 0.203 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.797 0.203 0.000
M84 Disorders of continuity of bone
0.794 0.206 0.000
I50.0 Congestive heart failure
0.794 0.206 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.793 0.207 0.000
M75.4 Impingement syndrome of shoulder
0.793 0.207 0.000
N03 Chronic nephritic syndrome
0.792 0.208 0.000
Z50.5 Speech therapy
0.791 0.209 0.000
S43.0 Dislocation of shoulder joint
0.790 0.210 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.790 0.210 0.000
I10-I15 Hypertensive diseases
0.789 0.211 0.000
Z60.2 Living alone
0.788 0.212 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.786 0.214 0.000
Z34.8 Supervision of other normal pregnancy
0.785 0.215 0.000
X60-X84 Intentional self-harm
0.784 0.216 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.783 0.217 0.000
T42.4 Benzodiazepines
0.782 0.218 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.781 0.219 0.000
I63.9 Cerebral infarction, unspecified
0.778 0.222 0.000
O60-O75 Complications of labour and delivery
0.777 0.223 0.000
N04 Nephrotic syndrome
0.776 0.224 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.776 0.224 0.000
M00-M03 Infectious arthropathies
0.775 0.224 0.000
S70-S79 Injuries to the hip and thigh
0.775 0.225 0.000
I08.0 Disorders of both mitral and aortic valves
0.774 0.226 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.772 0.228 0.000
S61.8 Open wound of other parts of wrist and hand
0.771 0.229 0.000
M60-M63 Disorders of muscles
0.771 0.229 0.000
M41 Scoliosis
0.771 0.229 0.000
S42 Fracture of shoulder and upper arm
0.771 0.229 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.771 0.229 0.000
S00.1 Contusion of eyelid and periocular area
0.770 0.230 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.769 0.231 0.000
M75.9 Shoulder lesion, unspecified
0.769 0.231 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.768 0.232 0.000
M77 Other enthesopathies
0.768 0.232 0.000
S52.5 Fracture of lower end of radius
0.768 0.232 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.767 0.233 0.000
E83.5 Disorders of calcium metabolism
0.766 0.234 0.000
S01.1 Open wound of eyelid and periocular area
0.765 0.235 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.765 0.235 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.765 0.235 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.765 0.235 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.764 0.236 0.000
F60-F69 Disorders of adult personality and behaviour
0.763 0.237 0.000
S64 Injury of nerves at wrist and hand level
0.763 0.237 0.000
W20-W49 Exposure to inanimate mechanical forces
0.763 0.237 0.000
F32.9 Depressive episode, unspecified
0.762 0.238 0.000
M71 Other bursopathies
0.761 0.239 0.000
S60.8 Other superficial injuries of wrist and hand
0.761 0.239 0.000
S61.0 Open wound of finger(s) without damage to nail
0.760 0.240 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.760 0.240 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.760 0.240 0.000
M79.60 Pain in limb (Multiple sites)
0.760 0.240 0.000
N25-N29 Other disorders of kidney and ureter
0.760 0.240 0.000
Z51.8 Other specified medical care
0.758 0.242 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.757 0.243 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.757 0.243 0.000
M06.9 Rheumatoid arthritis, unspecified
0.756 0.244 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.755 0.245 0.000
I85 Oesophageal varices
0.755 0.245 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.755 0.245 0.000
S05 Injury of eye and orbit
0.754 0.246 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.753 0.246 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.752 0.248 0.000
M43.1 Spondylolisthesis
0.752 0.248 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.752 0.248 0.000
E83.4 Disorders of magnesium metabolism
0.748 0.252 0.000
M86-M90 Other osteopathies
0.747 0.253 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.743 0.256 0.000
Z47 Other orthopaedic follow-up care
0.740 0.260 0.000
I67.1 Cerebral aneurysm, nonruptured
0.740 0.260 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.739 0.260 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.739 0.261 0.000
R05 Cough
0.736 0.264 0.000
I45 Other conduction disorders
0.736 0.264 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.736 0.264 0.000
Z49.2 Other dialysis
0.735 0.265 0.000
I05 Rheumatic mitral valve diseases
0.735 0.265 0.000
Chapter VIII Diseases of the ear and mastoid process
0.735 0.265 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.734 0.265 0.000
M79.66 Pain in limb (Lower leg)
0.734 0.266 0.000
M45 Ankylosing spondylitis
0.734 0.266 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.733 0.267 0.000
S50 Superficial injury of forearm
0.731 0.269 0.000
I87 Other disorders of veins
0.730 0.270 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.729 0.271 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.729 0.271 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.728 0.272 0.000
S01.7 Multiple open wounds of head
0.728 0.272 0.000
C50 Malignant neoplasm of breast
0.727 0.273 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.727 0.273 0.000
S40 Superficial injury of shoulder and upper arm
0.727 0.273 0.000
R74 Abnormal serum enzyme levels
0.726 0.274 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.726 0.274 0.000
M72 Fibroblastic disorders
0.724 0.276 0.000
M79.63 Pain in limb (Forearm)
0.724 0.276 0.000
S01.5 Open wound of lip and oral cavity
0.723 0.277 0.000
I31 Other diseases of pericardium
0.723 0.277 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.721 0.279 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.720 0.280 0.000
I69.3 Sequelae of cerebral infarction
0.719 0.281 0.000
R47-R49 Symptoms and signs involving speech and voice
0.719 0.281 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.719 0.281 0.000
E40-E46 Malnutrition
0.718 0.281 0.000
M79.67 Pain in limb (Ankle and foot)
0.718 0.282 0.000
S52.0 Fracture of upper end of ulna
0.718 0.282 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E13 Other specified diabetes mellitus
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E20-E35 Disorders of other endocrine glands
0.717 0.283 0.000
E11.8 With unspecified complications
0.716 0.283 0.000
E11.7 With multiple complications
0.716 0.283 0.000
E11.6 With other specified complications
0.716 0.283 0.000
E11.1 With ketoacidosis
0.716 0.283 0.000
E11.0 With coma
0.716 0.283 0.000
M76 Enthesopathies of lower limb, excluding foot
0.716 0.283 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.716 0.283 0.000
M79.5 Residual foreign body in soft tissue
0.716 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.716 0.284 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.715 0.285 0.000
I00-I02 Acute rheumatic fever
0.715 0.285 0.000
S00.8 Superficial injury of other parts of head
0.715 0.285 0.000
S52.50 Fracture of lower end of radius (closed)
0.714 0.286 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.714 0.286 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.714 0.286 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.714 0.286 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.714 0.286 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.714 0.286 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.714 0.286 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.714 0.286 0.000
T36 Poisoning by systemic antibiotics
0.714 0.286 0.000
S20-S29 Injuries to the thorax
0.714 0.286 0.000
M75.8 Other shoulder lesions
0.713 0.287 0.000
R42 Dizziness and giddiness
0.713 0.287 0.000
I62 Other nontraumatic intracranial haemorrhage
0.713 0.287 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.711 0.289 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.711 0.289 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.710 0.290 0.000
S06 Intracranial injury
0.709 0.291 0.000
R76 Other abnormal immunological findings in serum
0.708 0.292 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.708 0.292 0.000
M91-M94 Chondropathies
0.706 0.294 0.000
M75.0 Adhesive capsulitis of shoulder
0.705 0.295 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.704 0.296 0.000
Z50.1 Other physical therapy
0.704 0.296 0.000
Z54 Convalescence
0.704 0.296 0.000
Z44 Fitting and adjustment of external prosthetic device
0.704 0.296 0.000
N99-N99 Other disorders of the genitourinary system
0.703 0.297 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.703 0.297 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.703 0.297 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.702 0.298 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.701 0.299 0.000
S08 Traumatic amputation of part of head
0.701 0.299 0.000
S07 Crushing injury of head
0.701 0.299 0.000
S04 Injury of cranial nerves
0.701 0.299 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.701 0.299 0.000
I07 Rheumatic tricuspid valve diseases
0.701 0.299 0.000
T79-T79 Certain early complications of trauma
0.700 0.300 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.700 0.300 0.000
Q60-Q64 Congenital malformations of the urinary system
0.700 0.300 0.000
E65-E68 Obesity and other hyperalimentation
0.699 0.301 0.000
Z57.3 Occupational exposure to other air contaminants
0.699 0.301 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.698 0.302 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.698 0.302 0.000
I51.7 Cardiomegaly
0.697 0.303 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.697 0.303 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.697 0.303 0.000
T17 Foreign body in respiratory tract
0.697 0.303 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.697 0.303 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.697 0.303 0.000
C51-C58 Malignant neoplasms of female genital organs
0.696 0.304 0.000
R40 Somnolence, stupor and coma
0.696 0.304 0.000
M79.9 Soft tissue disorder, unspecified
0.695 0.305 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.695 0.305 0.000
M79.3 Panniculitis, unspecified
0.695 0.305 0.000
M79.2 Neuralgia and neuritis, unspecified
0.695 0.305 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.695 0.305 0.000
Z49.0 Preparatory care for dialysis
0.694 0.306 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.694 0.306 0.000
S67 Crushing injury of wrist and hand
0.694 0.306 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.694 0.306 0.000
E50-E64 Other nutritional deficiencies
0.693 0.306 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.692 0.308 0.000
F70-F79 Mental retardation
0.692 0.308 0.000
D69 Purpura and other haemorrhagic conditions
0.692 0.308 0.000
O72 Postpartum haemorrhage
0.692 0.308 0.000
M79.10 Myalgia (Multiple sites)
0.691 0.309 0.000
D50-D53 Nutritional anaemias
0.691 0.309 0.000
I86 Varicose veins of other sites
0.691 0.309 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.691 0.309 0.000
R27 Other lack of coordination
0.690 0.309 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.690 0.310 0.000
Z51.0 Radiotherapy session
0.690 0.310 0.000
E85 Amyloidosis
0.690 0.310 0.000
E84 Cystic fibrosis
0.690 0.310 0.000
E79 Disorders of purine and pyrimidine metabolism
0.690 0.310 0.000
E77 Disorders of glycoprotein metabolism
0.690 0.310 0.000
E76 Disorders of glycosaminoglycan metabolism
0.690 0.310 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.690 0.310 0.000
E74 Other disorders of carbohydrate metabolism
0.690 0.310 0.000
E73 Lactose intolerance
0.690 0.310 0.000
E72 Other disorders of amino-acid metabolism
0.690 0.310 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.690 0.310 0.000
E70 Disorders of aromatic amino-acid metabolism
0.690 0.310 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.690 0.310 0.000
S51 Open wound of forearm
0.687 0.312 0.000
S65 Injury of blood vessels at wrist and hand level
0.687 0.313 0.000
E88 Other metabolic disorders
0.687 0.313 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.687 0.313 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.686 0.314 0.000
Y43 Primarily systemic agents
0.686 0.314 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.685 0.314 0.000
R77 Other abnormalities of plasma proteins
0.685 0.314 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.685 0.314 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.685 0.314 0.000
R71 Abnormality of red blood cells
0.685 0.314 0.000
F80-F89 Disorders of psychological development
0.685 0.315 0.000
G90-G99 Other disorders of the nervous system
0.685 0.315 0.000
M46 Other inflammatory spondylopathies
0.685 0.315 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.685 0.315 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.684 0.316 0.000
D03 Melanoma in situ
0.684 0.316 0.000
S61.1 Open wound of finger(s) with damage to nail
0.684 0.316 0.000
N17 Acute renal failure
0.683 0.317 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.682 0.317 0.000
N03.9 Unspecified
0.681 0.319 0.000
E14.8 With unspecified complications
0.681 0.319 0.000
E14.7 With multiple complications
0.681 0.319 0.000
E14.6 With other specified complications
0.681 0.319 0.000
E14.5 With peripheral circulatory complications
0.681 0.319 0.000
E14.4 With neurological complications
0.681 0.319 0.000
E14.2 Withrenal complications
0.681 0.319 0.000
E14.1 With ketoacidosis
0.681 0.319 0.000
E14.0 With coma
0.681 0.319 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.680 0.319 0.000
S48 Traumatic amputation of shoulder and upper arm
0.680 0.319 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.680 0.319 0.000
S44 Injury of nerves at shoulder and upper arm level
0.680 0.319 0.000
S41 Open wound of shoulder and upper arm
0.680 0.319 0.000
S47 Crushing injury of shoulder and upper arm
0.680 0.319 0.000
S01.4 Open wound of cheek and temporomandibular area
0.680 0.319 0.000
S01.3 Open wound of ear
0.680 0.319 0.000
S01.2 Open wound of nose
0.680 0.319 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.680 0.319 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.680 0.320 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.679 0.321 0.000
Z52.3 Bone marrow donor
0.679 0.321 0.000
N18.8 Other chronic renal failure
0.679 0.321 0.000
N18.2 Chronic kidney disease, stage 2
0.679 0.321 0.000
N18.1 Chronic kidney disease, stage 1
0.679 0.321 0.000
M05 Seropositive rheumatoid arthritis
0.679 0.321 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.679 0.321 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.678 0.322 0.000
N06 Isolated proteinuria with specified morphological lesion
0.678 0.322 0.000
N05 Unspecified nephritic syndrome
0.678 0.322 0.000
N01 Rapidly progressive nephritic syndrome
0.678 0.322 0.000
N00 Acute nephritic syndrome
0.678 0.322 0.000
T92 Sequelae of injuries of upper limb
0.678 0.322 0.000
R79.0 Abnormal level of blood mineral
0.678 0.322 0.000
I34 Nonrheumatic mitral valve disorders
0.677 0.323 0.000
T87 Complications peculiar to reattachment and amputation
0.677 0.323 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.676 0.324 0.000
T43.9 Psychotropic drug, unspecified
0.676 0.324 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.676 0.324 0.000
T43.6 Psychostimulants with abuse potential
0.676 0.324 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.676 0.324 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.676 0.324 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.676 0.324 0.000
M79.68 Pain in limb (Other)
0.676 0.324 0.000
M79.64 Pain in limb (Hand)
0.676 0.324 0.000
M79.61 Pain in limb (Shoulder region)
0.676 0.324 0.000
M84.0 Malunion of fracture
0.675 0.324 0.000
T66-T78 Other and unspecified effects of external causes
0.675 0.325 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.675 0.325 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.674 0.326 0.000
D37.5 Rectum
0.674 0.326 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.673 0.327 0.000
Y35-Y36 Legal intervention and operations of war
0.673 0.327 0.000
Y10-Y34 Event of undetermined intent
0.673 0.327 0.000
Y00-Y09 Assault
0.673 0.327 0.000
X85-X99 Assault
0.673 0.327 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.673 0.327 0.000
X50-X57 Overexertion, travel and privation
0.673 0.327 0.000
X30-X39 Exposure to forces of nature
0.673 0.327 0.000
X20-X29 Contact with venomous animals and plants
0.673 0.327 0.000
X10-X19 Contact with heat and hot substances
0.673 0.327 0.000
X00-X09 Exposure to smoke, fire and flames
0.673 0.327 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.673 0.327 0.000
W75-W84 Other accidental threats to breathing
0.673 0.327 0.000
W65-W74 Accidental drowning and submersion
0.673 0.327 0.000
W50-W64 Exposure to animate mechanical forces
0.673 0.327 0.000
V98-V99 Other and unspecified transport accidents
0.673 0.327 0.000
V95-V97 Air and space transport accidents
0.673 0.327 0.000
V90-V94 Water transport accidents
0.673 0.327 0.000
V80-V89 Other land transport accidents
0.673 0.327 0.000
V70-V79 Bus occupant injured in transport accident
0.673 0.327 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.673 0.327 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.673 0.327 0.000
V40-V49 Car occupant injured in transport accident
0.673 0.327 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.673 0.327 0.000
V01-V09 Pedestrian injured in transport accident
0.673 0.327 0.000
I85.9 Oesophageal varices without bleeding
0.673 0.327 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.672 0.328 0.000
S68 Traumatic amputation of wrist and hand
0.671 0.328 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.670 0.330 0.000
S61.7 Multiple open wounds of wrist and hand
0.670 0.330 0.000
T93 Sequelae of injuries of lower limb
0.669 0.331 0.000
N02.9 Unspecified
0.669 0.331 0.000
Z65 Problems related to other psychosocial circumstances
0.669 0.331 0.000
Z64 Problems related to certain psychosocial circumstances
0.669 0.331 0.000
Z62 Other problems related to upbringing
0.669 0.331 0.000
Z61 Problems related to negative life events in childhood
0.669 0.331 0.000
Z59 Problems related to housing and economic circumstances
0.669 0.331 0.000
Z58 Problems related to physical environment
0.669 0.331 0.000
Z56 Problems related to employment and unemployment
0.669 0.331 0.000
Z55 Problems related to education and literacy
0.669 0.331 0.000
F03 Unspecified dementia
0.668 0.332 0.000
I81 Portal vein thrombosis
0.667 0.333 0.000
I09 Other rheumatic heart diseases
0.667 0.333 0.000
I06 Rheumatic aortic valve diseases
0.667 0.333 0.000
R29.4 Clicking hip
0.666 0.333 0.000
R29.3 Abnormal posture
0.666 0.333 0.000
R29.2 Abnormal reflex
0.666 0.333 0.000
R29.1 Meningismus
0.666 0.333 0.000
R29.0 Tetany
0.666 0.333 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.666 0.334 0.000
G70-G73 Diseases of myoneural junction and muscle
0.666 0.334 0.000
C50.4 Upper-outer quadrant of breast
0.665 0.335 0.000
Z63 Other problems related to primary support group, including family circumstances
0.664 0.335 0.000
M42 Spinal osteochondrosis
0.663 0.337 0.000
M40 Kyphosis and lordosis
0.663 0.337 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.663 0.337 0.000
O85-O92 Complications predominantly related to the puerperium
0.663 0.337 0.000
E11.5 With peripheral circulatory complications
0.663 0.337 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.663 0.337 0.000
S59 Other and unspecified injuries of forearm
0.662 0.338 0.000
S58 Traumatic amputation of forearm
0.662 0.338 0.000
S57 Crushing injury of forearm
0.662 0.338 0.000
S56 Injury of muscle and tendon at forearm level
0.662 0.338 0.000
S55 Injury of blood vessels at forearm level
0.662 0.338 0.000
S54 Injury of nerves at forearm level
0.662 0.338 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.662 0.338 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.661 0.338 0.000
S69 Other and unspecified injuries of wrist and hand
0.661 0.339 0.000
Z50.2 Alcohol rehabilitation
0.661 0.339 0.000
S90-S99 Injuries to the ankle and foot
0.661 0.339 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.661 0.339 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.661 0.339 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.661 0.339 0.000
T42.3 Barbiturates
0.661 0.339 0.000
T42.2 Succinimides and oxazolidinediones
0.661 0.339 0.000
T42.1 Iminostilbenes
0.661 0.339 0.000
T42.0 Hydantoin derivatives
0.661 0.339 0.000
M41.9 Scoliosis, unspecified
0.660 0.340 0.000
D05 Carcinoma in situ of breast
0.660 0.340 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.659 0.341 0.000
C15 Malignant neoplasm of oesophagus
0.659 0.341 0.000
W00-W19 Falls
0.659 0.341 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.659 0.341 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.659 0.341 0.000
D46 Myelodysplastic syndromes
0.658 0.341 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.657 0.343 0.000
B15-B19 Viral hepatitis
0.656 0.344 0.000
I71 Aortic aneurysm and dissection
0.656 0.344 0.000
M79.7 Fibromyalgia
0.656 0.344 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.656 0.344 0.000
T86 Failure and rejection of transplanted organs and tissues
0.656 0.344 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.655 0.345 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.655 0.345 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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