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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs79423523
log Bayes Factor = 15.7536
Chromosome 2   position 58,673,886  (GRCh37) Explore rs79423523 on Ensembl!
Variant rs79423523 is part of Cluster X0210

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
Chapter VIII Diseases of the ear and mastoid process
0.997 0.003 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.996 0.004 0.000
J20-J22 Other acute lower respiratory infections
0.993 0.007 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.993 0.007 0.000
Chapter IX Diseases of the circulatory system
0.990 0.010 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.989 0.011 0.000
J22 Unspecified acute lower respiratory infection
0.989 0.011 0.000
Chapter V Mental and behavioural disorders
0.987 0.013 0.000
H65-H75 Diseases of middle ear and mastoid
0.984 0.016 0.000
J09-J18 Influenza and pneumonia
0.979 0.021 0.000
S00-S09 Injuries to the head
0.976 0.024 0.000
Chapter XXI Factors influencing health status and contact with health services
0.975 0.025 0.000
M70-M79 Other soft tissue disorders
0.974 0.026 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.972 0.028 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.969 0.031 0.000
I30-I52 Other forms of heart disease
0.966 0.034 0.000
Chapter VII Diseases of the eye and adnexa
0.965 0.035 0.000
M45-M49 Spondylopathies
0.955 0.045 0.000
I50 Heart failure
0.951 0.049 0.000
J18 Pneumonia, organism unspecified
0.951 0.049 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.950 0.050 0.000
M75 Shoulder lesions
0.950 0.050 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.948 0.052 0.000
H90-H95 Other disorders of ear
0.944 0.056 0.000
Y43 Primarily systemic agents
0.943 0.057 0.000
S00 Superficial injury of head
0.940 0.060 0.000
M05-M14 Inflammatory polyarthropathies
0.940 0.060 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.937 0.063 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.935 0.065 0.000
R21 Rash and other nonspecific skin eruption
0.933 0.067 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.930 0.070 0.000
J18.1 Lobar pneumonia, unspecified
0.929 0.071 0.000
M47 Spondylosis
0.928 0.072 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.922 0.078 0.000
Y43.3 Other antineoplastic drugs
0.922 0.078 0.000
M75.1 Rotator cuff syndrome
0.918 0.082 0.000
I05-I09 Chronic rheumatic heart diseases
0.906 0.094 0.000
W00-W19 Falls
0.905 0.095 0.000
Z51 Other medical care
0.901 0.099 0.000
I50.1 Left ventricular failure
0.896 0.104 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.895 0.105 0.000
M47.8 Other spondylosis
0.890 0.110 0.000
I50.0 Congestive heart failure
0.887 0.113 0.000
H72 Perforation of tympanic membrane
0.886 0.114 0.000
R50-R69 General symptoms and signs
0.883 0.117 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.880 0.120 0.000
E70-E90 Metabolic disorders
0.878 0.122 0.000
H66 Suppurative and unspecified otitis media
0.877 0.122 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.877 0.123 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.874 0.126 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.870 0.130 0.000
S00.8 Superficial injury of other parts of head
0.861 0.139 0.000
M40-M43 Deforming dorsopathies
0.859 0.141 0.000
I20-I25 Ischaemic heart diseases
0.857 0.143 0.000
H53-H54 Visual disturbances and blindness
0.852 0.148 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.848 0.152 0.000
F30-F39 Mood [affective] disorders
0.846 0.154 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.845 0.155 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.845 0.155 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.843 0.157 0.000
I20 Angina pectoris
0.842 0.158 0.000
I08 Multiple valve diseases
0.842 0.158 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.841 0.159 0.000
S40-S49 Injuries to the shoulder and upper arm
0.841 0.159 0.000
H55-H59 Other disorders of eye and adnexa
0.840 0.160 0.000
S09 Other and unspecified injuries of head
0.839 0.161 0.000
M13 Other arthritis
0.837 0.163 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.836 0.164 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.830 0.170 0.000
F41 Other anxiety disorders
0.830 0.170 0.000
R59 Enlarged lymph nodes
0.828 0.172 0.000
M75.4 Impingement syndrome of shoulder
0.827 0.173 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.827 0.173 0.000
I20.9 Angina pectoris, unspecified
0.826 0.174 0.000
H92 Otalgia and effusion of ear
0.826 0.174 0.000
Z50 Care involving use of rehabilitation procedures
0.823 0.177 0.000
D69 Purpura and other haemorrhagic conditions
0.822 0.178 0.000
M06 Other rheumatoid arthritis
0.819 0.181 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.816 0.184 0.000
J60-J70 Lung diseases due to external agents
0.809 0.191 0.000
H73 Other disorders of tympanic membrane
0.809 0.191 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.809 0.191 0.000
S00.1 Contusion of eyelid and periocular area
0.808 0.192 0.000
Z41 Procedures for purposes other than remedying health state
0.808 0.192 0.000
F60-F69 Disorders of adult personality and behaviour
0.806 0.194 0.000
M77 Other enthesopathies
0.804 0.195 0.000
D80-D89 Certain disorders involving the immune mechanism
0.804 0.196 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.802 0.198 0.000
I08.0 Disorders of both mitral and aortic valves
0.801 0.199 0.000
I34 Nonrheumatic mitral valve disorders
0.801 0.199 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.800 0.200 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.799 0.201 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.798 0.202 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.797 0.203 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.797 0.203 0.000
W19 Unspecified fall
0.796 0.204 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.795 0.205 0.000
H65 Nonsuppurative otitis media
0.794 0.206 0.000
S00.9 Superficial injury of head, part unspecified
0.793 0.207 0.000
D69.6 Thrombocytopenia, unspecified
0.791 0.209 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.791 0.209 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.791 0.209 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.789 0.210 0.000
E83 Disorders of mineral metabolism
0.788 0.212 0.000
H74 Other disorders of middle ear and mastoid
0.788 0.212 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.787 0.213 0.000
W20-W49 Exposure to inanimate mechanical forces
0.785 0.214 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.785 0.215 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.785 0.215 0.000
M47.9 Spondylosis, unspecified
0.784 0.216 0.000
F99-F99 Unspecified mental disorder
0.784 0.216 0.000
M47.82 Other spondylosis (Cervical region)
0.784 0.216 0.000
H90 Conductive and sensorineural hearing loss
0.783 0.217 0.000
Z42 Follow-up care involving plastic surgery
0.783 0.217 0.000
E40-E46 Malnutrition
0.783 0.217 0.000
I42 Cardiomyopathy
0.781 0.219 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.780 0.220 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.780 0.220 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.779 0.221 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.779 0.221 0.000
Z51.8 Other specified medical care
0.777 0.223 0.000
H54 Blindness and low vision
0.777 0.223 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.776 0.224 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.776 0.224 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.775 0.225 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.775 0.225 0.000
Z51.2 Other chemotherapy
0.774 0.226 0.000
H80-H83 Diseases of inner ear
0.773 0.227 0.000
I38 Endocarditis, valve unspecified
0.773 0.227 0.000
R60 Oedema, not elsewhere classified
0.772 0.228 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.772 0.228 0.000
I84 Haemorrhoids
0.771 0.229 0.000
H66.3 Other chronic suppurative otitis media
0.770 0.230 0.000
S70-S79 Injuries to the hip and thigh
0.770 0.230 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.770 0.230 0.000
R50 Fever of unknown origin
0.770 0.230 0.000
Chapter I Certain infectious and parasitic diseases
0.769 0.231 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.768 0.232 0.000
R59.0 Localised enlarged lymph nodes
0.768 0.232 0.000
M80-M85 Disorders of bone density and structure
0.767 0.233 0.000
H04 Disorders of lachrymal system
0.765 0.235 0.000
J00-J06 Acute upper respiratory infections
0.765 0.235 0.000
M13.9 Arthritis, unspecified
0.763 0.237 0.000
J90-J94 Other diseases of pleura
0.763 0.237 0.000
V10-V19 Pedal cyclist injured in transport accident
0.762 0.238 0.000
J20 Acute bronchitis
0.760 0.240 0.000
F43 Reaction to severe stress, and adjustment disorders
0.759 0.241 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.759 0.241 0.000
J10 Influenza due to identified influenza virus
0.757 0.243 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.757 0.243 0.000
E50-E64 Other nutritional deficiencies
0.756 0.244 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.755 0.245 0.000
Z51.9 Medical care, unspecified
0.753 0.247 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.753 0.247 0.000
H02 Other disorders of eyelid
0.753 0.247 0.000
F80-F89 Disorders of psychological development
0.751 0.249 0.000
Chapter XXII Codes for special purposes
0.750 0.250 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.750 0.250 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.749 0.251 0.000
M75.2 Bicipital tendinitis
0.746 0.254 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.746 0.254 0.000
F41.9 Anxiety disorder, unspecified
0.744 0.256 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.744 0.256 0.000
R42 Dizziness and giddiness
0.743 0.257 0.000
V80-V89 Other land transport accidents
0.743 0.257 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.742 0.258 0.000
S90-S99 Injuries to the ankle and foot
0.742 0.258 0.000
H60-H62 Diseases of external ear
0.742 0.258 0.000
S09.9 Unspecified injury of head
0.742 0.258 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.741 0.259 0.000
H71 Cholesteatoma of middle ear
0.740 0.260 0.000
M75.3 Calcific tendinitis of shoulder
0.740 0.260 0.000
I50.9 Heart failure, unspecified
0.740 0.260 0.000
Z48 Other surgical follow-up care
0.739 0.261 0.000
O00-O08 Pregnancy with abortive outcome
0.735 0.265 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.733 0.267 0.000
M06.9 Rheumatoid arthritis, unspecified
0.732 0.268 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.732 0.268 0.000
M05 Seropositive rheumatoid arthritis
0.729 0.271 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.728 0.271 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.728 0.272 0.000
S02 Fracture of skull and facial bones
0.727 0.273 0.000
R54 Senility
0.727 0.273 0.000
F40 Phobic anxiety disorders
0.726 0.274 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.726 0.274 0.000
M11 Other crystal arthropathies
0.725 0.275 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.725 0.275 0.000
R45 Symptoms and signs involving emotional state
0.725 0.275 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.724 0.276 0.000
E20-E35 Disorders of other endocrine glands
0.723 0.277 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.723 0.277 0.000
I35 Nonrheumatic aortic valve disorders
0.723 0.277 0.000
I20.0 Unstable angina
0.722 0.278 0.000
T66-T78 Other and unspecified effects of external causes
0.721 0.279 0.000
R61 Hyperhidrosis
0.721 0.279 0.000
M43 Other deforming dorsopathies
0.720 0.279 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.720 0.280 0.000
M47.89 Other spondylosis (Site unspecified)
0.720 0.280 0.000
R63 Symptoms and signs concerning food and fluid intake
0.718 0.282 0.000
H92.1 Otorrhoea
0.717 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
D86 Sarcoidosis
0.717 0.283 0.000
T87 Complications peculiar to reattachment and amputation
0.715 0.285 0.000
T86 Failure and rejection of transplanted organs and tissues
0.715 0.285 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.714 0.286 0.000
M91-M94 Chondropathies
0.714 0.286 0.000
M60-M63 Disorders of muscles
0.714 0.286 0.000
M00-M03 Infectious arthropathies
0.714 0.286 0.000
M86-M90 Other osteopathies
0.713 0.287 0.000
J21 Acute bronchiolitis
0.712 0.288 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.712 0.288 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.712 0.288 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.712 0.288 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.712 0.288 0.000
E88 Other metabolic disorders
0.710 0.289 0.000
I00-I02 Acute rheumatic fever
0.710 0.290 0.000
Chapter VI Diseases of the nervous system
0.709 0.291 0.000
M65-M68 Disorders of synovium and tendon
0.709 0.291 0.000
M79.8 Other specified soft tissue disorders
0.709 0.291 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.709 0.291 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.709 0.291 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.708 0.292 0.000
Y52 Agents primarily affecting the cardiovascular system
0.708 0.292 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.707 0.292 0.000
F70-F79 Mental retardation
0.707 0.292 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.707 0.293 0.000
I49 Other cardiac arrhythmias
0.707 0.293 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.707 0.293 0.000
M47.86 Other spondylosis (Lumbar region)
0.706 0.294 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.705 0.294 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.705 0.295 0.000
H70 Mastoiditis and related conditions
0.705 0.295 0.000
H69 Other disorders of Eustachian tube
0.705 0.295 0.000
H68 Eustachian salpingitis and obstruction
0.705 0.295 0.000
H67 Otitis media in diseases classified elsewhere
0.705 0.295 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.704 0.296 0.000
X60-X84 Intentional self-harm
0.704 0.296 0.000
M45 Ankylosing spondylitis
0.703 0.296 0.000
E83.4 Disorders of magnesium metabolism
0.703 0.297 0.000
W18 Other fall on same level
0.702 0.298 0.000
J17 Pneumonia in diseases classified elsewhere
0.702 0.298 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.702 0.298 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.702 0.298 0.000
J12 Viral pneumonia, not elsewhere classified
0.702 0.298 0.000
J11 Influenza, virus not identified
0.702 0.298 0.000
J14 Pneumonia due to Haemophilus influenzae
0.702 0.298 0.000
J09 Influenza due to certain identified influenza virus
0.702 0.298 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.702 0.298 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.701 0.299 0.000
H66.9 Otitis media, unspecified
0.701 0.299 0.000
H91 Other hearing loss
0.701 0.299 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.701 0.299 0.000
V20-V29 Motorcycle rider injured in transport accident
0.701 0.299 0.000
S08 Traumatic amputation of part of head
0.700 0.300 0.000
S07 Crushing injury of head
0.700 0.300 0.000
S06 Intracranial injury
0.700 0.300 0.000
S05 Injury of eye and orbit
0.700 0.300 0.000
S04 Injury of cranial nerves
0.700 0.300 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.700 0.300 0.000
Chapter II Neoplasms
0.700 0.300 0.000
I33 Acute and subacute endocarditis
0.699 0.301 0.000
M76 Enthesopathies of lower limb, excluding foot
0.698 0.302 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.698 0.302 0.000
M71 Other bursopathies
0.698 0.302 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.698 0.302 0.000
Y59 Other and unspecified vaccines and biological substances
0.697 0.303 0.000
Y58 Bacterial vaccines
0.697 0.303 0.000
Y57 Other and unspecified drugs and medicaments
0.697 0.303 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.697 0.303 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.697 0.303 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.697 0.303 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.697 0.303 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.697 0.303 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.697 0.303 0.000
Y48 Anaesthetics and therapeutic gases
0.697 0.303 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.697 0.303 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.697 0.303 0.000
Y44 Agents primarily affecting blood constituents
0.697 0.303 0.000
J30-J39 Other diseases of upper respiratory tract
0.696 0.304 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.695 0.305 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.694 0.306 0.000
J18.0 Bronchopneumonia, unspecified
0.693 0.306 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.693 0.306 0.000
I52 Other heart disorders in diseases classified elsewhere
0.693 0.307 0.000
I48 Atrial fibrillation and flutter
0.693 0.307 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.693 0.307 0.000
I41 Myocarditis in diseases classified elsewhere
0.693 0.307 0.000
I40 Acute myocarditis
0.693 0.307 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.693 0.307 0.000
I37 Pulmonary valve disorders
0.693 0.307 0.000
I36 Nonrheumatic tricuspid valve disorders
0.693 0.307 0.000
I32 Pericarditis in diseases classified elsewhere
0.693 0.307 0.000
I30 Acute pericarditis
0.693 0.307 0.000
Z52 Donors of organs and tissues
0.692 0.308 0.000
I84.5 External haemorrhoids without complication
0.692 0.308 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.692 0.308 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.691 0.309 0.000
Y40 Systemic antibiotics
0.691 0.309 0.000
W19.3 Sports and athletics area
0.690 0.310 0.000
L60-L75 Disorders of skin appendages
0.690 0.310 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.688 0.312 0.000
H55 Nystagmus and other irregular eye movements
0.688 0.312 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.688 0.312 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.687 0.313 0.000
M41 Scoliosis
0.687 0.313 0.000
H30-H36 Disorders of choroid and retina
0.687 0.313 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.687 0.313 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.687 0.313 0.000
T39.1 4-Aminophenol derivatives
0.687 0.313 0.000
J18.9 Pneumonia, unspecified
0.687 0.313 0.000
E86 Volume depletion
0.686 0.314 0.000
C15-C26 Malignant neoplasms of digestive organs
0.685 0.315 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.685 0.315 0.000
M49 Spondylopathies in diseases classified elsewhere
0.684 0.315 0.000
S42 Fracture of shoulder and upper arm
0.684 0.316 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.684 0.316 0.000
M47.2 Other spondylosis with radiculopathy
0.683 0.316 0.000
H73.8 Other specified disorders of tympanic membrane
0.683 0.317 0.000
Z40 Prophylactic surgery
0.683 0.317 0.000
M77.1 Lateral epicondylitis
0.683 0.317 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.683 0.317 0.000
H43-H45 Disorders of vitreous body and globe
0.683 0.317 0.000
F32 Depressive episode
0.682 0.318 0.000
J18.8 Other pneumonia, organism unspecified
0.681 0.318 0.000
J18.2 Hypostatic pneumonia, unspecified
0.681 0.318 0.000
H10-H13 Disorders of conjunctiva
0.681 0.319 0.000
Z54 Convalescence
0.681 0.319 0.000
Z49 Care involving dialysis
0.681 0.319 0.000
Z44 Fitting and adjustment of external prosthetic device
0.681 0.319 0.000
M75.8 Other shoulder lesions
0.681 0.319 0.000
M75.9 Shoulder lesion, unspecified
0.681 0.319 0.000
Z50.2 Alcohol rehabilitation
0.681 0.319 0.000
H95.1 Other disorders following mastoidectomy
0.680 0.320 0.000
S20-S29 Injuries to the thorax
0.679 0.321 0.000
R22.2 Localised swelling, mass and lump, trunk
0.678 0.322 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.677 0.322 0.000
W13 Fall from, out of or through building or structure
0.677 0.323 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.677 0.323 0.000
E46 Unspecified protein-energy malnutrition
0.677 0.323 0.000
Z50.5 Speech therapy
0.677 0.323 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.677 0.323 0.000
Y43.9 Primarily systemic agent, unspecified
0.676 0.324 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.676 0.324 0.000
Y43.6 Enzymes, not elsewhere classified
0.676 0.324 0.000
Y43.5 Acidifying and alkalising agents
0.676 0.324 0.000
Y43.4 Immunosuppressive agents
0.676 0.324 0.000
Y43.2 Antineoplastic natural products
0.676 0.324 0.000
Y43.1 Antineoplastic antimetabolites
0.676 0.324 0.000
Y43.0 Antiallergic and antiemetic drugs
0.676 0.324 0.000
F60 Specific personality disorders
0.676 0.324 0.000
S01 Open wound of head
0.676 0.324 0.000
F20 Schizophrenia
0.675 0.325 0.000
S32 Fracture of lumbar spine and pelvis
0.675 0.325 0.000
S00.7 Multiple superficial injuries of head
0.674 0.326 0.000
S00.5 Superficial injury of lip and oral cavity
0.674 0.326 0.000
S00.4 Superficial injury of ear
0.674 0.326 0.000
S00.3 Superficial injury of nose
0.674 0.326 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.674 0.326 0.000
F31 Bipolar affective disorder
0.674 0.326 0.000
M14 Arthropathies in other diseases classified elsewhere
0.674 0.326 0.000
M12 Other specific arthropathies
0.674 0.326 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.674 0.326 0.000
M08 Juvenile arthritis
0.674 0.326 0.000
M07 Psoriatic and enteropathic arthropathies
0.674 0.326 0.000
H54.9 Unspecified visual impairment (binocular)
0.673 0.326 0.000
F22 Persistent delusional disorders
0.673 0.327 0.000
H93 Other disorders of ear, not elsewhere classified
0.672 0.327 0.000
W10 Fall on and from stairs and steps
0.672 0.328 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.672 0.328 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.672 0.328 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.672 0.328 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.672 0.328 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.672 0.328 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.672 0.328 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.672 0.328 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.672 0.328 0.000
T36 Poisoning by systemic antibiotics
0.672 0.328 0.000
I31 Other diseases of pericardium
0.671 0.329 0.000
D55-D59 Haemolytic anaemias
0.670 0.329 0.000
Z51.0 Radiotherapy session
0.670 0.330 0.000
S41 Open wound of shoulder and upper arm
0.668 0.332 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.668 0.332 0.000
H90.5 Sensorineural hearing loss, unspecified
0.668 0.332 0.000
R22.1 Localised swelling, mass and lump, neck
0.667 0.333 0.000
M46 Other inflammatory spondylopathies
0.667 0.333 0.000
I07 Rheumatic tricuspid valve diseases
0.667 0.333 0.000
Q60-Q64 Congenital malformations of the urinary system
0.666 0.334 0.000
I84.8 Unspecified haemorrhoids with other complications
0.666 0.334 0.000
D68 Other coagulation defects
0.666 0.334 0.000
M47.1 Other spondylosis with myelopathy
0.665 0.335 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.665 0.335 0.000
T92 Sequelae of injuries of upper limb
0.665 0.335 0.000
W06 Fall involving bed
0.664 0.336 0.000
I84.2 Internal haemorrhoids without complication
0.664 0.336 0.000
R23 Other skin changes
0.663 0.337 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.662 0.337 0.000
Z47 Other orthopaedic follow-up care
0.661 0.339 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.661 0.339 0.000
F48 Other neurotic disorders
0.661 0.339 0.000
F44 Dissociative [conversion] disorders
0.661 0.339 0.000
F42 Obsessive-compulsive disorder
0.661 0.339 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.661 0.339 0.000
Z13 Special screening examination for other diseases and disorders
0.661 0.339 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.660 0.340 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.659 0.341 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.659 0.341 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.657 0.343 0.000
H20 Iridocyclitis
0.657 0.343 0.000
F29 Unspecified nonorganic psychosis
0.657 0.343 0.000
I34.0 Mitral (valve) insufficiency
0.657 0.343 0.000
Z29 Need for other prophylactic measures
0.655 0.345 0.000
M48 Other spondylopathies
0.655 0.345 0.000
W19.9 Unspecified place
0.655 0.345 0.000
Y42.5 Other oestrogens and progestogens
0.655 0.345 0.000
Y60.0 During surgical operation
0.654 0.346 0.000
R59.1 Generalised enlarged lymph nodes
0.653 0.347 0.000
Z50.0 Cardiac rehabilitation
0.653 0.347 0.000
R60.9 Oedema, unspecified
0.653 0.347 0.000
A30-A49 Other bacterial diseases
0.653 0.347 0.000
S50-S59 Injuries to the elbow and forearm
0.652 0.348 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.652 0.348 0.000
H65.3 Chronic mucoid otitis media
0.652 0.348 0.000
Z50.1 Other physical therapy
0.651 0.349 0.000
I09 Other rheumatic heart diseases
0.650 0.350 0.000
I06 Rheumatic aortic valve diseases
0.650 0.350 0.000
I05 Rheumatic mitral valve diseases
0.650 0.350 0.000
J90 Pleural effusion, not elsewhere classified
0.650 0.350 0.000
W17 Other fall from one level to another
0.649 0.351 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.649 0.351 0.000
W15 Fall from cliff
0.649 0.351 0.000
W14 Fall from tree
0.649 0.351 0.000
W12 Fall on and from scaffolding
0.649 0.351 0.000
W11 Fall on and from ladder
0.649 0.351 0.000
W09 Fall involving playground equipment
0.649 0.351 0.000
W08 Fall involving other furniture
0.649 0.351 0.000
W07 Fall involving chair
0.649 0.351 0.000
W05 Fall involving wheelchair
0.649 0.351 0.000
W04 Fall while being carried or supported by other persons
0.649 0.351 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.649 0.351 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.649 0.351 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.649 0.351 0.000
W00 Fall on same level involving ice and snow
0.649 0.351 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.648 0.352 0.000
H74.4 Polyp of middle ear
0.647 0.353 0.000
R81 Glycosuria
0.647 0.353 0.000
I47 Paroxysmal tachycardia
0.646 0.354 0.000
Z51.6 Desensitisation to allergens
0.646 0.354 0.000
C18 Malignant neoplasm of colon
0.646 0.354 0.000
I82 Other venous embolism and thrombosis
0.646 0.354 0.000
H02.5 Other disorders affecting eyelid function
0.645 0.355 0.000
F45 Somatoform disorders
0.643 0.357 0.000
F41.1 Generalised anxiety disorder
0.643 0.357 0.000
H92.0 Otalgia
0.643 0.357 0.000
F43.2 Adjustment disorders
0.642 0.358 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.642 0.358 0.000
F33 Recurrent depressive disorder
0.642 0.358 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.642 0.358 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.642 0.358 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.642 0.358 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.642 0.358 0.000
T83.2 Mechanical complication of graft of urinary organ
0.642 0.358 0.000
R82 Other abnormal findings in urine
0.639 0.360 0.000
H81 Disorders of vestibular function
0.639 0.361 0.000
R50.9 Fever, unspecified
0.639 0.361 0.000
F99 Mental disorder, not otherwise specified
0.639 0.361 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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