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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78815966
log Bayes Factor = 8.22947
Chromosome 4   position 86,755,698  (GRCh37) Explore rs78815966 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
# Top node
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.998 0.002 0.000
A30-A49 Other bacterial diseases
0.994 0.006 0.000
A41 Other septicaemia
0.990 0.010 0.000
C51-C58 Malignant neoplasms of female genital organs
0.985 0.015 0.000
A41.9 Septicaemia, unspecified
0.985 0.015 0.000
C79 Secondary malignant neoplasm of other sites
0.985 0.015 0.000
Chapter IX Diseases of the circulatory system
0.973 0.027 0.000
I30-I52 Other forms of heart disease
0.970 0.030 0.000
C78.7 Secondary malignant neoplasm of liver
0.964 0.036 0.000
C50-C50 Malignant neoplasm of breast
0.960 0.040 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.954 0.046 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.951 0.049 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.951 0.049 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.944 0.056 0.000
Chapter XX External causes of morbidity and mortality
0.942 0.058 0.000
I49 Other cardiac arrhythmias
0.940 0.060 0.000
I35 Nonrheumatic aortic valve disorders
0.935 0.065 0.000
Chapter X Diseases of the respiratory system
0.933 0.067 0.000
B95-B98 Bacterial, viral and other infectious agents
0.932 0.068 0.000
C50 Malignant neoplasm of breast
0.931 0.069 0.000
I05-I09 Chronic rheumatic heart diseases
0.924 0.076 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.923 0.077 0.000
Chapter XXII Codes for special purposes
0.921 0.079 0.000
I60-I69 Cerebrovascular diseases
0.916 0.084 0.000
C15-C26 Malignant neoplasms of digestive organs
0.913 0.087 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.913 0.087 0.000
Chapter V Mental and behavioural disorders
0.911 0.089 0.000
Chapter VI Diseases of the nervous system
0.905 0.095 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.897 0.103 0.000
I49.0 Ventricular fibrillation and flutter
0.894 0.106 0.000
I08 Multiple valve diseases
0.893 0.107 0.000
C43 Malignant melanoma of skin
0.892 0.108 0.000
C54 Malignant neoplasm of corpus uteri
0.887 0.113 0.000
C25 Malignant neoplasm of pancreas
0.885 0.115 0.000
C50.1 Central portion of breast
0.880 0.120 0.000
J90-J94 Other diseases of pleura
0.880 0.120 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.879 0.121 0.000
I49.9 Cardiac arrhythmia, unspecified
0.876 0.124 0.000
I35.0 Aortic (valve) stenosis
0.872 0.128 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.868 0.132 0.000
I46 Cardiac arrest
0.868 0.132 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.868 0.132 0.000
C50.5 Lower-outer quadrant of breast
0.866 0.134 0.000
Y95 Nosocomial condition
0.865 0.135 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.863 0.137 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.862 0.138 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.861 0.139 0.000
I63 Cerebral infarction
0.860 0.140 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.859 0.141 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.855 0.145 0.000
C25.9 Pancreas, unspecified
0.845 0.155 0.000
C80 Malignant neoplasm without specification of site
0.842 0.158 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.841 0.159 0.000
I47 Paroxysmal tachycardia
0.840 0.160 0.000
C53 Malignant neoplasm of cervix uteri
0.839 0.161 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.837 0.163 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.833 0.167 0.000
C79.2 Secondary malignant neoplasm of skin
0.831 0.169 0.000
J00-J06 Acute upper respiratory infections
0.827 0.173 0.000
D00-D09 In situ neoplasms
0.825 0.175 0.000
C56 Malignant neoplasm of ovary
0.824 0.176 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.823 0.177 0.000
C50.8 Overlapping lesion of breast
0.822 0.178 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.820 0.180 0.000
C78.2 Secondary malignant neoplasm of pleura
0.820 0.180 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.820 0.180 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.819 0.181 0.000
B25-B34 Other viral diseases
0.819 0.181 0.000
C54.1 Endometrium
0.817 0.183 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.817 0.183 0.000
J81 Pulmonary oedema
0.815 0.185 0.000
I35.1 Aortic (valve) insufficiency
0.814 0.186 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.809 0.191 0.000
C78.0 Secondary malignant neoplasm of lung
0.809 0.191 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.806 0.194 0.000
I36 Nonrheumatic tricuspid valve disorders
0.806 0.194 0.000
A80-A89 Viral infections of the central nervous system
0.806 0.194 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.805 0.195 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.805 0.195 0.000
D37.7 Other digestive organs
0.804 0.196 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.803 0.197 0.000
I69 Sequelae of cerebrovascular disease
0.803 0.197 0.000
I63.8 Other cerebral infarction
0.801 0.199 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.800 0.200 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.798 0.202 0.000
J00 Acute nasopharyngitis [common cold]
0.797 0.203 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.794 0.206 0.000
I33 Acute and subacute endocarditis
0.794 0.206 0.000
U80 Agent resistant to penicillin and related antibiotics
0.793 0.207 0.000
I47.1 Supraventricular tachycardia
0.793 0.207 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.793 0.207 0.000
I44 Atrioventricular and left bundle-branch block
0.793 0.207 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.792 0.208 0.000
B35-B49 Mycoses
0.792 0.208 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.791 0.209 0.000
I46.0 Cardiac arrest with successful resuscitation
0.788 0.212 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.786 0.214 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.784 0.216 0.000
G90-G99 Other disorders of the nervous system
0.783 0.217 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.781 0.219 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.775 0.225 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.774 0.226 0.000
C50.6 Axillary tail of breast
0.773 0.227 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.771 0.229 0.000
F41 Other anxiety disorders
0.771 0.229 0.000
A41.8 Other specified septicaemia
0.770 0.230 0.000
C51 Malignant neoplasm of vulva
0.767 0.233 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.767 0.233 0.000
C79.6 Secondary malignant neoplasm of ovary
0.766 0.234 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.765 0.235 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.764 0.236 0.000
C90.2 Plasmacytoma, extramedullary
0.763 0.237 0.000
I35.9 Aortic valve disorder, unspecified
0.758 0.242 0.000
A15-A19 Tuberculosis
0.758 0.242 0.000
A40 Streptococcal septicaemia
0.757 0.243 0.000
A49 Bacterial infection of unspecified site
0.755 0.245 0.000
J91 Pleural effusion in conditions classified elsewhere
0.754 0.246 0.000
Q80-Q89 Other congenital malformations
0.753 0.247 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.752 0.248 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.751 0.249 0.000
G40-G47 Episodic and paroxysmal disorders
0.751 0.249 0.000
I49.4 Other and unspecified premature depolarisation
0.751 0.249 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.751 0.249 0.000
I31 Other diseases of pericardium
0.751 0.249 0.000
C71 Malignant neoplasm of brain
0.751 0.249 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.750 0.250 0.000
J20-J22 Other acute lower respiratory infections
0.750 0.250 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.749 0.251 0.000
Y00-Y09 Assault
0.748 0.252 0.000
I44.2 Atrioventricular block, complete
0.745 0.255 0.000
J60-J70 Lung diseases due to external agents
0.745 0.255 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.745 0.255 0.000
C81 Hodgkin's disease
0.743 0.256 0.000
F30-F39 Mood [affective] disorders
0.742 0.258 0.000
G47.3 Sleep apnoea
0.742 0.258 0.000
G47 Sleep disorders
0.741 0.258 0.000
J84 Other interstitial pulmonary diseases
0.741 0.259 0.000
C80.9 Malignant neoplasm, unspecified
0.740 0.260 0.000
A00-A09 Intestinal infectious diseases
0.738 0.262 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.736 0.263 0.000
C44 Other malignant neoplasms of skin
0.736 0.264 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.735 0.265 0.000
C53.9 Cervix uteri, unspecified
0.734 0.266 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.733 0.267 0.000
D37.5 Rectum
0.733 0.267 0.000
A48 Other bacterial diseases, not elsewhere classified
0.732 0.268 0.000
Q60-Q64 Congenital malformations of the urinary system
0.731 0.269 0.000
B99-B99 Other infectious diseases
0.731 0.269 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.730 0.270 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.729 0.271 0.000
J94 Other pleural conditions
0.727 0.273 0.000
C95 Leukaemia of unspecified cell type
0.726 0.274 0.000
W75-W84 Other accidental threats to breathing
0.726 0.274 0.000
C77.4 Inguinal and lower limb lymph nodes
0.724 0.276 0.000
G20-G26 Extrapyramidal and movement disorders
0.723 0.277 0.000
Q00-Q07 Congenital malformations of the nervous system
0.720 0.280 0.000
J93 Pneumothorax
0.719 0.281 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.719 0.281 0.000
I50 Heart failure
0.718 0.282 0.000
W50-W64 Exposure to animate mechanical forces
0.718 0.282 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B65-B83 Helminthiases
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.716 0.284 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.716 0.284 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.716 0.284 0.000
C18 Malignant neoplasm of colon
0.715 0.285 0.000
G30-G32 Other degenerative diseases of the nervous system
0.715 0.285 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.714 0.285 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.714 0.286 0.000
A44 Bartonellosis
0.713 0.287 0.000
A43 Nocardiosis
0.713 0.287 0.000
A42 Actinomycosis
0.713 0.287 0.000
A39 Meningococcal infection
0.713 0.287 0.000
A37 Whooping cough
0.713 0.287 0.000
A36 Diphtheria
0.713 0.287 0.000
A32 Listeriosis
0.713 0.287 0.000
A31 Infection due to other mycobacteria
0.713 0.287 0.000
A30 Leprosy [Hansen's disease]
0.713 0.287 0.000
A38 Scarlet fever
0.713 0.287 0.000
A35 Other tetanus
0.713 0.287 0.000
A34 Obstetrical tetanus
0.713 0.287 0.000
A33 Tetanus neonatorum
0.713 0.287 0.000
C44.7 Skin of lower limb, including hip
0.713 0.287 0.000
C17 Malignant neoplasm of small intestine
0.712 0.287 0.000
C25.0 Head of pancreas
0.712 0.288 0.000
W00-W19 Falls
0.711 0.289 0.000
A41.4 Septicaemia due to anaerobes
0.710 0.290 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.710 0.290 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.710 0.290 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.709 0.291 0.000
F41.9 Anxiety disorder, unspecified
0.709 0.291 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.708 0.292 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.706 0.293 0.000
C58 Malignant neoplasm of placenta
0.706 0.293 0.000
C52 Malignant neoplasm of vagina
0.706 0.293 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.706 0.294 0.000
I07 Rheumatic tricuspid valve diseases
0.706 0.294 0.000
G70-G73 Diseases of myoneural junction and muscle
0.705 0.295 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.705 0.295 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.705 0.295 0.000
C77.3 Axillary and upper limb lymph nodes
0.703 0.297 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.702 0.297 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.702 0.298 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.700 0.300 0.000
I62 Other nontraumatic intracranial haemorrhage
0.699 0.301 0.000
C50.0 Nipple and areola
0.699 0.301 0.000
D37.2 Small intestine
0.698 0.302 0.000
I00-I02 Acute rheumatic fever
0.697 0.303 0.000
V40-V49 Car occupant injured in transport accident
0.696 0.304 0.000
Y42.7 Androgens and anabolic congeners
0.696 0.304 0.000
D05 Carcinoma in situ of breast
0.696 0.304 0.000
I52 Other heart disorders in diseases classified elsewhere
0.695 0.304 0.000
I48 Atrial fibrillation and flutter
0.695 0.304 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.695 0.304 0.000
I41 Myocarditis in diseases classified elsewhere
0.695 0.304 0.000
I40 Acute myocarditis
0.695 0.304 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.695 0.304 0.000
I37 Pulmonary valve disorders
0.695 0.304 0.000
I32 Pericarditis in diseases classified elsewhere
0.695 0.304 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.695 0.305 0.000
U51 Admission status on psychiatric patients
0.693 0.307 0.000
I38 Endocarditis, valve unspecified
0.692 0.308 0.000
X20-X29 Contact with venomous animals and plants
0.690 0.310 0.000
I69.3 Sequelae of cerebral infarction
0.690 0.310 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.690 0.310 0.000
C43.5 Malignant melanoma of trunk
0.690 0.310 0.000
I61 Intracerebral haemorrhage
0.689 0.311 0.000
C88 Malignant immunoproliferative diseases
0.688 0.312 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.688 0.312 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.688 0.312 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.688 0.312 0.000
B34 Viral infection of unspecified site
0.687 0.312 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.684 0.316 0.000
C94 Other leukaemias of specified cell type
0.684 0.316 0.000
C93 Monocytic leukaemia
0.684 0.316 0.000
C86 Other specified types of T/NK-cell lymphoma
0.684 0.316 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.684 0.316 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.684 0.316 0.000
D48.0 Bone and articular cartilage
0.683 0.317 0.000
C50.2 Upper-inner quadrant of breast
0.681 0.319 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.680 0.319 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.680 0.320 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.680 0.320 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.679 0.321 0.000
C77.8 Lymph nodes of multiple regions
0.679 0.321 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.679 0.321 0.000
F02 Dementia in other diseases classified elsewhere
0.677 0.323 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.675 0.324 0.000
Y35-Y36 Legal intervention and operations of war
0.675 0.324 0.000
Y10-Y34 Event of undetermined intent
0.675 0.324 0.000
X85-X99 Assault
0.675 0.324 0.000
X30-X39 Exposure to forces of nature
0.675 0.324 0.000
X00-X09 Exposure to smoke, fire and flames
0.675 0.324 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.675 0.324 0.000
W65-W74 Accidental drowning and submersion
0.675 0.324 0.000
V98-V99 Other and unspecified transport accidents
0.675 0.324 0.000
V95-V97 Air and space transport accidents
0.675 0.324 0.000
V90-V94 Water transport accidents
0.675 0.324 0.000
V70-V79 Bus occupant injured in transport accident
0.675 0.324 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.675 0.324 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.675 0.324 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.675 0.324 0.000
V01-V09 Pedestrian injured in transport accident
0.675 0.324 0.000
X50-X57 Overexertion, travel and privation
0.675 0.325 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.675 0.325 0.000
J90 Pleural effusion, not elsewhere classified
0.674 0.326 0.000
I49.2 Junctional premature depolarisation
0.674 0.326 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.674 0.326 0.000
I30 Acute pericarditis
0.673 0.327 0.000
D06 Carcinoma in situ of cervix uteri
0.673 0.327 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.669 0.331 0.000
I33.0 Acute and subacute infective endocarditis
0.668 0.332 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.667 0.333 0.000
C25.1 Body of pancreas
0.666 0.334 0.000
C25.2 Tail of pancreas
0.665 0.334 0.000
A86 Unspecified viral encephalitis
0.664 0.336 0.000
I09 Other rheumatic heart diseases
0.663 0.337 0.000
I06 Rheumatic aortic valve diseases
0.663 0.337 0.000
I49.3 Ventricular premature depolarisation
0.663 0.337 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.662 0.337 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.662 0.338 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.662 0.338 0.000
I60 Subarachnoid haemorrhage
0.661 0.339 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.659 0.341 0.000
I31.9 Disease of pericardium, unspecified
0.657 0.343 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.656 0.343 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.656 0.343 0.000
Q82 Other congenital malformations of skin
0.656 0.344 0.000
F41.2 Mixed anxiety and depressive disorder
0.655 0.345 0.000
C23 Malignant neoplasm of gallbladder
0.655 0.345 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.655 0.345 0.000
Q35-Q37 Cleft lip and cleft palate
0.655 0.345 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.655 0.345 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.653 0.347 0.000
F70-F79 Mental retardation
0.653 0.347 0.000
C76.0 Head, face and neck
0.653 0.347 0.000
I51 Complications and ill-defined descriptions of heart disease
0.652 0.348 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.651 0.348 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.650 0.350 0.000
D45 Polycythaemia vera
0.650 0.350 0.000
B49 Unspecified mycosis
0.649 0.351 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.648 0.351 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.648 0.351 0.000
I35.8 Other aortic valve disorders
0.648 0.352 0.000
J92 Pleural plaque
0.648 0.352 0.000
F00 Dementia in Alzheimer's disease
0.648 0.352 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.647 0.353 0.000
C82.0 Small cleaved cell, follicular
0.647 0.353 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.646 0.354 0.000
C04 Malignant neoplasm of floor of mouth
0.646 0.354 0.000
F05.9 Delirium, unspecified
0.646 0.354 0.000
I46.9 Cardiac arrest, unspecified
0.644 0.356 0.000
C69 Malignant neoplasm of eye and adnexa
0.644 0.356 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.643 0.357 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.643 0.357 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.643 0.357 0.000
Y98 Lifestyle-related condition
0.643 0.357 0.000
Y97 Environmental-pollution-related condition
0.643 0.357 0.000
Y96 Work-related condition
0.643 0.357 0.000
A46 Erysipelas
0.642 0.358 0.000
C71.3 Parietal lobe
0.641 0.359 0.000
I08.9 Multiple valve disease, unspecified
0.640 0.360 0.000
I08.8 Other multiple valve diseases
0.640 0.360 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.640 0.360 0.000
C43.8 Overlapping malignant melanoma of skin
0.640 0.360 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.640 0.360 0.000
C43.0 Malignant melanoma of lip
0.640 0.360 0.000
U80.1 Methicillin resistant agent
0.640 0.360 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.639 0.361 0.000
C64-C68 Malignant neoplasms of urinary tract
0.639 0.361 0.000
D48.1 Connective and other soft tissue
0.637 0.363 0.000
Q39 Congenital malformations of oesophagus
0.636 0.364 0.000
A08 Viral and other specified intestinal infections
0.636 0.364 0.000
C54.9 Corpus uteri, unspecified
0.636 0.364 0.000
C54.8 Overlapping lesion of corpus uteri
0.636 0.364 0.000
C54.3 Fundus uteri
0.636 0.364 0.000
C54.2 Myometrium
0.636 0.364 0.000
C54.0 Isthmus uteri
0.636 0.364 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.635 0.365 0.000
C25.8 Overlapping lesion of pancreas
0.634 0.366 0.000
C25.7 Other parts of pancreas
0.634 0.366 0.000
C25.4 Endocrine pancreas
0.634 0.366 0.000
C25.3 Pancreatic duct
0.634 0.366 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.634 0.366 0.000
B37 Candidiasis
0.633 0.367 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.632 0.368 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.631 0.369 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.630 0.370 0.000
C83.1 Small cleaved cell (diffuse)
0.630 0.370 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.630 0.370 0.000
V20-V29 Motorcycle rider injured in transport accident
0.629 0.371 0.000
C44.6 Skin of upper limb, including shoulder
0.628 0.371 0.000
V80-V89 Other land transport accidents
0.627 0.373 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.625 0.375 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.624 0.376 0.000
B02 Zoster [herpes zoster]
0.623 0.377 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.623 0.377 0.000
I46.1 Sudden cardiac death, so described
0.623 0.377 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.623 0.377 0.000
C15 Malignant neoplasm of oesophagus
0.622 0.378 0.000
C34 Malignant neoplasm of bronchus and lung
0.622 0.378 0.000
Y40 Systemic antibiotics
0.622 0.378 0.000
C43.9 Malignant melanoma of skin, unspecified
0.622 0.378 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.622 0.378 0.000
F30 Manic episode
0.621 0.379 0.000
G30 Alzheimer's disease
0.621 0.379 0.000
G95 Other diseases of spinal cord
0.620 0.380 0.000
A49.9 Bacterial infection, unspecified
0.619 0.380 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.619 0.381 0.000
D37.9 Digestive organ, unspecified
0.619 0.381 0.000
D37.6 Liver, gallbladder and bile ducts
0.619 0.381 0.000
D37.3 Appendix
0.619 0.381 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.618 0.382 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.618 0.382 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.618 0.382 0.000
C70 Malignant neoplasm of meninges
0.618 0.382 0.000
C24.0 Extrahepatic bile duct
0.618 0.382 0.000
F60-F69 Disorders of adult personality and behaviour
0.618 0.382 0.000
G25 Other extrapyramidal and movement disorders
0.617 0.383 0.000
F99-F99 Unspecified mental disorder
0.617 0.383 0.000
F80-F89 Disorders of psychological development
0.617 0.383 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.617 0.383 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.617 0.383 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.617 0.383 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.616 0.383 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.616 0.384 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.616 0.384 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.616 0.384 0.000
U81 Agent resistant to vancomycin and related antibiotics
0.616 0.384 0.000
U50 Level of care administered to neonates
0.616 0.384 0.000
U07 Emergency use of U07
0.616 0.384 0.000
U06 Emergency use of U06
0.616 0.384 0.000
U04 Severe acute respiratory syndrome [SARS]
0.616 0.384 0.000
U52 First in a series of a regular day/night admissions
0.616 0.384 0.000
C21 Malignant neoplasm of anus and anal canal
0.615 0.384 0.000
B27 Infectious mononucleosis
0.616 0.384 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.615 0.385 0.000
J01 Acute sinusitis
0.614 0.386 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.613 0.386 0.000
M70-M79 Other soft tissue disorders
0.613 0.387 0.000
G82 Paraplegia and tetraplegia
0.613 0.387 0.000
Y59 Other and unspecified vaccines and biological substances
0.613 0.387 0.000
Y58 Bacterial vaccines
0.613 0.387 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.613 0.387 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.613 0.387 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.613 0.387 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.613 0.387 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.613 0.387 0.000
J04 Acute laryngitis and tracheitis
0.612 0.387 0.000
C24.9 Biliary tract, unspecified
0.610 0.389 0.000
C51.9 Vulva, unspecified
0.610 0.390 0.000
D48.7 Other specified sites
0.610 0.390 0.000
X60-X84 Intentional self-harm
0.610 0.390 0.000
Y00 Assault by blunt object
0.610 0.390 0.000
I49.8 Other specified cardiac arrhythmias
0.609 0.391 0.000
D37.0 Lip, oral cavity and pharynx
0.609 0.391 0.000
C01 Malignant neoplasm of base of tongue
0.608 0.392 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.608 0.392 0.000
C77.5 Intrapelvic lymph nodes
0.608 0.392 0.000
G90 Disorders of autonomic nervous system
0.608 0.392 0.000
Y48 Anaesthetics and therapeutic gases
0.607 0.393 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.607 0.393 0.000
A40.9 Streptococcal septicaemia, unspecified
0.606 0.394 0.000
J93.1 Other spontaneous pneumothorax
0.605 0.395 0.000
J94.8 Other specified pleural conditions
0.605 0.395 0.000
A05 Other bacterial foodborne intoxications
0.604 0.396 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.604 0.396 0.000
Y57 Other and unspecified drugs and medicaments
0.604 0.396 0.000
C90.3 Solitary plasmacytoma
0.603 0.397 0.000
C90.1 Plasma cell leukaemia
0.603 0.397 0.000
D39.1 Ovary
0.603 0.397 0.000
C53.8 Overlapping lesion of cervix uteri
0.602 0.398 0.000
C53.1 Exocervix
0.602 0.398 0.000
C53.0 Endocervix
0.602 0.398 0.000
G83 Other paralytic syndromes
0.601 0.399 0.000
Chapter VIII Diseases of the ear and mastoid process
0.601 0.399 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.600 0.400 0.000
J80 Adult respiratory distress syndrome
0.597 0.403 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.596 0.404 0.000
J02 Acute pharyngitis
0.595 0.405 0.000
C90.0 Multiple myeloma
0.595 0.405 0.000
J21 Acute bronchiolitis
0.592 0.408 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.592 0.408 0.000
C81.9 Hodgkin's disease, unspecified
0.592 0.408 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.592 0.408 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.592 0.408 0.000
D37.1 Stomach
0.592 0.408 0.000
G93 Other disorders of brain
0.591 0.409 0.000
W20-W49 Exposure to inanimate mechanical forces
0.590 0.410 0.000
D09 Carcinoma in situ of other and unspecified sites
0.590 0.410 0.000
C18.0 Caecum
0.589 0.411 0.000
C24.1 Ampulla of Vater
0.589 0.411 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.588 0.412 0.000
F09 Unspecified organic or symptomatic mental disorder
0.588 0.412 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.588 0.412 0.000
Q63 Other congenital malformations of kidney
0.588 0.412 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.588 0.412 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.588 0.412 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.588 0.412 0.000
C50.3 Lower-inner quadrant of breast
0.587 0.412 0.000
F43 Reaction to severe stress, and adjustment disorders
0.587 0.413 0.000
B33 Other viral diseases, not elsewhere classified
0.587 0.413 0.000
B30 Viral conjunctivitis
0.587 0.413 0.000
B26 Mumps
0.587 0.413 0.000
G70 Myasthenia gravis and other myoneural disorders
0.587 0.413 0.000
Q82.5 Congenital nonneoplastic naevus
0.586 0.413 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.586 0.414 0.000
M79.0 Rheumatism, unspecified
0.586 0.414 0.000
G41 Status epilepticus
0.586 0.414 0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically
0.586 0.414 0.000
F03 Unspecified dementia
0.585 0.415 0.000
D48.6 Breast
0.584 0.416 0.000
I47.0 Reentry ventricular arrhythmia
0.584 0.416 0.000
I05 Rheumatic mitral valve diseases
0.583 0.417 0.000
A87 Viral meningitis
0.583 0.417 0.000
Q05 Spina bifida
0.582 0.418 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.581 0.418 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.582 0.418 0.000
I49.5 Sick sinus syndrome
0.581 0.419 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.581 0.419 0.000
I67 Other cerebrovascular diseases
0.580 0.420 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.579 0.421 0.000
A08.4 Viral intestinal infection, unspecified
0.578 0.422 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.578 0.422 0.000
C13 Malignant neoplasm of hypopharynx
0.578 0.422 0.000
C11 Malignant neoplasm of nasopharynx
0.578 0.422 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.578 0.422 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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