TreeWAS – Variant ID: rs116869426

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	1.000	0.000	0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
I10-I15 Hypertensive diseases	1.000	0.000	0.000
J40-J47 Chronic lower respiratory diseases	1.000	0.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.999	0.001	0.000
J44 Other chronic obstructive pulmonary disease	0.999	0.001	0.000
R07 Pain in throat and chest	0.999	0.001	0.000
R03 Abnormal blood-pressure reading, without diagnosis	0.999	0.001	0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.998	0.002	0.000
R07.4 Chest pain, unspecified	0.997	0.003	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.995	0.005	0.000
R06 Abnormalities of breathing	0.994	0.006	0.000
R06.0 Dyspnoea	0.992	0.008	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.975	0.025	0.000
R07.0 Pain in throat	0.974	0.026	0.000
Chapter I Certain infectious and parasitic diseases	0.960	0.040	0.000
J47 Bronchiectasis	0.949	0.051	0.000
Chapter XX External causes of morbidity and mortality	0.948	0.052	0.000
I05-I09 Chronic rheumatic heart diseases	0.941	0.059	0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.937	0.063	0.000
J30-J39 Other diseases of upper respiratory tract	0.934	0.066	0.000
J46 Status asthmaticus	0.934	0.066	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.930	0.070	0.000
Chapter VI Diseases of the nervous system	0.924	0.076	0.000
I08 Multiple valve diseases	0.912	0.088	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.911	0.089	0.000
B95-B98 Bacterial, viral and other infectious agents	0.906	0.094	0.000
I12 Hypertensive renal disease	0.896	0.104	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.888	0.112	0.000
J34 Other disorders of nose and nasal sinuses	0.886	0.114	0.000
J00-J06 Acute upper respiratory infections	0.880	0.120	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.879	0.121	0.000
R23 Other skin changes	0.876	0.124	0.000
R20 Disturbances of skin sensation	0.870	0.130	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.870	0.130	0.000
E78.0 Pure hypercholesterolaemia	0.869	0.131	0.000
I08.0 Disorders of both mitral and aortic valves	0.868	0.132	0.000
E70-E90 Metabolic disorders	0.867	0.133	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.867	0.133	0.000
B35-B49 Mycoses	0.864	0.136	0.000
J02 Acute pharyngitis	0.851	0.149	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.845	0.155	0.000
I71 Aortic aneurysm and dissection	0.843	0.157	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.835	0.165	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.834	0.166	0.000
J02.9 Acute pharyngitis, unspecified	0.830	0.170	0.000
J34.2 Deviated nasal septum	0.826	0.174	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.825	0.175	0.000
S60-S69 Injuries to the wrist and hand	0.823	0.177	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.823	0.177	0.000
I12.0 Hypertensive renal disease with renal failure	0.823	0.177	0.000
R20.2 Paraesthesia of skin	0.822	0.178	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.821	0.179	0.000
G30-G32 Other degenerative diseases of the nervous system	0.820	0.180	0.000
S90-S99 Injuries to the ankle and foot	0.820	0.180	0.000
R05 Cough	0.817	0.183	0.000
R06.2 Wheezing	0.814	0.186	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.811	0.189	0.000
J09-J18 Influenza and pneumonia	0.809	0.191	0.000
R01 Cardiac murmurs and other cardiac sounds	0.808	0.192	0.000
R06.6 Hiccough	0.797	0.203	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.796	0.204	0.000
J39 Other diseases of upper respiratory tract	0.795	0.205	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.785	0.215	0.000
R27 Other lack of coordination	0.783	0.217	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.782	0.218	0.000
R07.2 Precordial pain	0.781	0.219	0.000
J40 Bronchitis, not specified as acute or chronic	0.781	0.219	0.000
Y52 Agents primarily affecting the cardiovascular system	0.780	0.220	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.780	0.220	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.778	0.222	0.000
B35 Dermatophytosis	0.773	0.227	0.000
S50-S59 Injuries to the elbow and forearm	0.773	0.227	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.768	0.232	0.000
T93 Sequelae of injuries of lower limb	0.766	0.234	0.000
G70-G73 Diseases of myoneural junction and muscle	0.763	0.236	0.000
R23.2 Flushing	0.760	0.240	0.000
J37 Chronic laryngitis and laryngotracheitis	0.758	0.242	0.000
Y40 Systemic antibiotics	0.757	0.243	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.755	0.245	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.753	0.247	0.000
W50-W64 Exposure to animate mechanical forces	0.749	0.251	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.746	0.254	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.745	0.255	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.742	0.258	0.000
R23.8 Other and unspecified skin changes	0.741	0.259	0.000
J34.8 Other specified disorders of nose and nasal sinuses	0.740	0.260	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.740	0.260	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.739	0.261	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.738	0.262	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.736	0.264	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.734	0.266	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.730	0.270	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.728	0.272	0.000
X60-X84 Intentional self-harm	0.728	0.272	0.000
Y46.4 Iminostilbenes	0.726	0.274	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.723	0.277	0.000
E78.2 Mixed hyperlipidaemia	0.723	0.277	0.000
G40-G47 Episodic and paroxysmal disorders	0.722	0.278	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.721	0.279	0.000
J95-J99 Other diseases of the respiratory system	0.721	0.279	0.000
I80 Phlebitis and thrombophlebitis	0.720	0.280	0.000
J45 Asthma	0.720	0.280	0.000
G90-G99 Other disorders of the nervous system	0.718	0.282	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
I15 Secondary hypertension	0.717	0.283	0.000
I13 Hypertensive heart and renal disease	0.717	0.283	0.000
J41 Simple and mucopurulent chronic bronchitis	0.717	0.283	0.000
I00-I02 Acute rheumatic fever	0.717	0.283	0.000
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.716	0.284	0.000
B15-B19 Viral hepatitis	0.716	0.284	0.000
B25-B34 Other viral diseases	0.716	0.284	0.000
Y57 Other and unspecified drugs and medicaments	0.713	0.287	0.000
R06.7 Sneezing	0.712	0.288	0.000
R06.3 Periodic breathing	0.712	0.288	0.000
S62 Fracture at wrist and hand level	0.710	0.290	0.000
S69 Other and unspecified injuries of wrist and hand	0.709	0.291	0.000
B65-B83 Helminthiases	0.708	0.292	0.000
S91 Open wound of ankle and foot	0.705	0.295	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.704	0.296	0.000
R27.0 Ataxia, unspecified	0.704	0.296	0.000
R06.1 Stridor	0.700	0.300	0.000
T79-T79 Certain early complications of trauma	0.700	0.300	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.698	0.302	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.698	0.302	0.000
G40 Epilepsy	0.697	0.303	0.000
G30 Alzheimer's disease	0.694	0.306	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.693	0.306	0.000
V80-V89 Other land transport accidents	0.693	0.307	0.000
E50-E64 Other nutritional deficiencies	0.693	0.307	0.000
E65-E68 Obesity and other hyperalimentation	0.693	0.307	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.692	0.308	0.000
V20-V29 Motorcycle rider injured in transport accident	0.690	0.310	0.000
E88 Other metabolic disorders	0.689	0.311	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.688	0.312	0.000
B50-B64 Protozoal diseases	0.688	0.312	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.688	0.312	0.000
A75-A79 Rickettsioses	0.688	0.312	0.000
A70-A74 Other diseases caused by chlamydiae	0.688	0.312	0.000
A65-A69 Other spirochaetal diseases	0.688	0.312	0.000
A20-A28 Certain zoonotic bacterial diseases	0.688	0.312	0.000
A15-A19 Tuberculosis	0.688	0.312	0.000
Y00-Y09 Assault	0.688	0.312	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.687	0.313	0.000
S67 Crushing injury of wrist and hand	0.687	0.313	0.000
S64 Injury of nerves at wrist and hand level	0.686	0.314	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.686	0.314	0.000
R23.3 Spontaneous ecchymoses	0.685	0.315	0.000
I05 Rheumatic mitral valve diseases	0.685	0.315	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.684	0.316	0.000
Chapter VIII Diseases of the ear and mastoid process	0.684	0.316	0.000
R47-R49 Symptoms and signs involving speech and voice	0.683	0.317	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.681	0.318	0.000
I11 Hypertensive heart disease	0.680	0.319	0.000
Y35-Y36 Legal intervention and operations of war	0.680	0.320	0.000
Y10-Y34 Event of undetermined intent	0.680	0.320	0.000
X85-X99 Assault	0.680	0.320	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.680	0.320	0.000
X30-X39 Exposure to forces of nature	0.680	0.320	0.000
X20-X29 Contact with venomous animals and plants	0.680	0.320	0.000
X10-X19 Contact with heat and hot substances	0.680	0.320	0.000
X00-X09 Exposure to smoke, fire and flames	0.680	0.320	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.680	0.320	0.000
W75-W84 Other accidental threats to breathing	0.680	0.320	0.000
W65-W74 Accidental drowning and submersion	0.680	0.320	0.000
V98-V99 Other and unspecified transport accidents	0.680	0.320	0.000
V95-V97 Air and space transport accidents	0.680	0.320	0.000
V90-V94 Water transport accidents	0.680	0.320	0.000
V70-V79 Bus occupant injured in transport accident	0.680	0.320	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.680	0.320	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.680	0.320	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.680	0.320	0.000
V01-V09 Pedestrian injured in transport accident	0.680	0.320	0.000
I08.8 Other multiple valve diseases	0.679	0.321	0.000
R23.1 Pallor	0.678	0.322	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.678	0.322	0.000
R06.4 Hyperventilation	0.678	0.322	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.676	0.324	0.000
I09 Other rheumatic heart diseases	0.675	0.325	0.000
I06 Rheumatic aortic valve diseases	0.675	0.325	0.000
S93.1 Dislocation of toe(s)	0.673	0.327	0.000
X50-X57 Overexertion, travel and privation	0.673	0.327	0.000
B99-B99 Other infectious diseases	0.671	0.329	0.000
B37 Candidiasis	0.670	0.330	0.000
J13 Pneumonia due to Streptococcus pneumoniae	0.668	0.332	0.000
B97 Viral agents as the cause of diseases classified to other chapters	0.667	0.333	0.000
Y59 Other and unspecified vaccines and biological substances	0.667	0.333	0.000
Y58 Bacterial vaccines	0.667	0.333	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.667	0.333	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.667	0.333	0.000
Y48 Anaesthetics and therapeutic gases	0.667	0.333	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.667	0.333	0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.667	0.333	0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.667	0.333	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.666	0.334	0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.666	0.334	0.000
B35.3 Tinea pedis	0.666	0.334	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.664	0.336	0.000
I78 Diseases of capillaries	0.663	0.337	0.000
Y40.0 Penicillins	0.663	0.337	0.000
R81 Glycosuria	0.663	0.337	0.000
I60-I69 Cerebrovascular diseases	0.662	0.338	0.000
J34.3 Hypertrophy of nasal turbinates	0.662	0.338	0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.662	0.338	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.661	0.339	0.000
G90 Disorders of autonomic nervous system	0.660	0.340	0.000
J39.2 Other diseases of pharynx	0.660	0.340	0.000
V40-V49 Car occupant injured in transport accident	0.659	0.341	0.000
S10-S19 Injuries to the neck	0.658	0.342	0.000
B49 Unspecified mycosis	0.655	0.345	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.654	0.346	0.000
I08.9 Multiple valve disease, unspecified	0.654	0.346	0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.654	0.346	0.000
T33-T35 Frostbite	0.653	0.346	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.653	0.346	0.000
T00-T07 Injuries involving multiple body regions	0.653	0.346	0.000
S68 Traumatic amputation of wrist and hand	0.653	0.347	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.653	0.347	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.652	0.348	0.000
I82 Other venous embolism and thrombosis	0.650	0.350	0.000
A80-A89 Viral infections of the central nervous system	0.649	0.351	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.648	0.352	0.000
I70 Atherosclerosis	0.647	0.353	0.000
R25 Abnormal involuntary movements	0.646	0.354	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.645	0.355	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.645	0.355	0.000
G40.9 Epilepsy, unspecified	0.644	0.356	0.000
Chapter XXII Codes for special purposes	0.644	0.356	0.000
S56 Injury of muscle and tendon at forearm level	0.642	0.358	0.000
B35.6 Tinea cruris	0.641	0.359	0.000
J30 Vasomotor and allergic rhinitis	0.641	0.359	0.000
G82 Paraplegia and tetraplegia	0.640	0.359	0.000
R01.0 Benign and innocent cardiac murmurs	0.640	0.360	0.000
I12.9 Hypertensive renal disease without renal failure	0.638	0.362	0.000
R80 Isolated proteinuria	0.638	0.362	0.000
S51 Open wound of forearm	0.638	0.362	0.000
R82 Other abnormal findings in urine	0.637	0.363	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.636	0.364	0.000
E78.1 Pure hyperglyceridaemia	0.635	0.365	0.000
R07.1 Chest pain on breathing	0.634	0.365	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.633	0.367	0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.631	0.368	0.000
J37.0 Chronic laryngitis	0.631	0.369	0.000
W00-W19 Falls	0.631	0.369	0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.631	0.369	0.000
J04 Acute laryngitis and tracheitis	0.631	0.369	0.000
J39.8 Other specified diseases of upper respiratory tract	0.630	0.370	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.628	0.372	0.000
R23.0 Cyanosis	0.628	0.372	0.000
S69.9 Unspecified injury of wrist and hand	0.628	0.372	0.000
J45.9 Asthma, unspecified	0.627	0.373	0.000
J34.0 Abscess, furuncle and carbuncle of nose	0.627	0.373	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.627	0.373	0.000
I67 Other cerebrovascular diseases	0.626	0.374	0.000
R20.8 Other and unspecified disturbances of skin sensation	0.626	0.374	0.000
Q50-Q56 Congenital malformations of genital organs	0.625	0.375	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.625	0.375	0.000
R20.3 Hyperaesthesia	0.624	0.376	0.000
R20.1 Hypoaesthesia of skin	0.624	0.376	0.000
R20.0 Anaesthesia of skin	0.624	0.376	0.000
J31.0 Chronic rhinitis	0.623	0.377	0.000
T66-T78 Other and unspecified effects of external causes	0.623	0.377	0.000
S91.3 Open wound of other parts of foot	0.623	0.377	0.000
E85 Amyloidosis	0.622	0.378	0.000
E84 Cystic fibrosis	0.622	0.378	0.000
E79 Disorders of purine and pyrimidine metabolism	0.622	0.378	0.000
E77 Disorders of glycoprotein metabolism	0.622	0.378	0.000
E76 Disorders of glycosaminoglycan metabolism	0.622	0.378	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.622	0.378	0.000
E74 Other disorders of carbohydrate metabolism	0.622	0.378	0.000
E73 Lactose intolerance	0.622	0.378	0.000
E72 Other disorders of amino-acid metabolism	0.622	0.378	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.622	0.378	0.000
E70 Disorders of aromatic amino-acid metabolism	0.622	0.378	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.622	0.378	0.000
E78.8 Other disorders of lipoprotein metabolism	0.621	0.379	0.000
E78.6 Lipoprotein deficiency	0.621	0.379	0.000
E78.3 Hyperchylomicronaemia	0.621	0.379	0.000
R01.1 Cardiac murmur, unspecified	0.621	0.379	0.000
W20-W49 Exposure to inanimate mechanical forces	0.620	0.380	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.620	0.380	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.620	0.380	0.000
E78.4 Other hyperlipidaemia	0.619	0.380	0.000
B48 Other mycoses, not elsewhere classified	0.619	0.381	0.000
B47 Mycetoma	0.619	0.381	0.000
B46 Zygomycosis	0.619	0.381	0.000
B45 Cryptococcosis	0.619	0.381	0.000
B43 Chromomycosis and phaeomycotic abscess	0.619	0.381	0.000
B42 Sporotrichosis	0.619	0.381	0.000
B41 Paracoccidioidomycosis	0.619	0.381	0.000
B40 Blastomycosis	0.619	0.381	0.000
B39 Histoplasmosis	0.619	0.381	0.000
B38 Coccidioidomycosis	0.619	0.381	0.000
B36 Other superficial mycoses	0.619	0.381	0.000
T98 Sequelae of other and unspecified effects of external causes	0.619	0.381	0.000
J34.1 Cyst and mucocele of nose and nasal sinus	0.619	0.381	0.000
J32 Chronic sinusitis	0.618	0.382	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.617	0.383	0.000
J11 Influenza, virus not identified	0.616	0.384	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.616	0.384	0.000
I71.0 Dissection of aorta [any part]	0.616	0.384	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.614	0.386	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.613	0.387	0.000
J36 Peritonsillar abscess	0.612	0.388	0.000
G70 Myasthenia gravis and other myoneural disorders	0.612	0.388	0.000
G61 Inflammatory polyneuropathy	0.612	0.388	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.612	0.388	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.611	0.389	0.000
J02.8 Acute pharyngitis due to other specified organisms	0.610	0.390	0.000
J02.0 Streptococcal pharyngitis	0.610	0.390	0.000
G83 Other paralytic syndromes	0.608	0.391	0.000
B24 Unspecified human immunodeficiency virus [HIV] disease	0.608	0.392	0.000
J10 Influenza due to identified influenza virus	0.608	0.392	0.000
S62.6 Fracture of other finger	0.608	0.392	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.606	0.394	0.000
J35 Chronic diseases of tonsils and adenoids	0.605	0.395	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.604	0.395	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.604	0.395	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.604	0.395	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.604	0.395	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.604	0.395	0.000
E86 Volume depletion	0.604	0.396	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.603	0.397	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.602	0.397	0.001
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.602	0.398	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.601	0.399	0.000
J01 Acute sinusitis	0.600	0.400	0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.600	0.400	0.000
S20-S29 Injuries to the thorax	0.599	0.400	0.000
I67.9 Cerebrovascular disease, unspecified	0.599	0.401	0.000
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters	0.599	0.401	0.000
S54 Injury of nerves at forearm level	0.599	0.401	0.000
R26 Abnormalities of gait and mobility	0.598	0.402	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.597	0.403	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.597	0.403	0.000
S70-S79 Injuries to the hip and thigh	0.596	0.403	0.000
Y54.5 Other diuretics	0.596	0.404	0.000
E20-E35 Disorders of other endocrine glands	0.596	0.404	0.000
R23.4 Changes in skin texture	0.596	0.404	0.000
S99 Other and unspecified injuries of ankle and foot	0.595	0.404	0.000
S62.2 Fracture of first metacarpal bone	0.595	0.405	0.000
T90 Sequelae of injuries of head	0.595	0.405	0.000
A63.0 Anogenital (venereal) warts	0.594	0.406	0.000
Y42.5 Other oestrogens and progestogens	0.593	0.406	0.000
J14 Pneumonia due to Haemophilus influenzae	0.592	0.408	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.592	0.408	0.000
T95 Sequelae of burns, corrosions and frostbite	0.591	0.409	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.591	0.409	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.591	0.409	0.000
R27.8 Other and unspecified lack of coordination	0.591	0.409	0.000
T91 Sequelae of injuries of neck and trunk	0.591	0.409	0.000
S65 Injury of blood vessels at wrist and hand level	0.590	0.410	0.000
S40-S49 Injuries to the shoulder and upper arm	0.590	0.410	0.000
Y95 Nosocomial condition	0.589	0.411	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.589	0.411	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.588	0.412	0.000
S98 Traumatic amputation of ankle and foot	0.588	0.412	0.000
S97 Crushing injury of ankle and foot	0.588	0.412	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.588	0.412	0.000
S95 Injury of blood vessels at ankle and foot level	0.588	0.412	0.000
S94 Injury of nerves at ankle and foot level	0.588	0.412	0.000
B44 Aspergillosis	0.588	0.412	0.000
I74 Arterial embolism and thrombosis	0.587	0.413	0.000
R03.1 Nonspecific low blood-pressure reading	0.587	0.413	0.000
I73 Other peripheral vascular diseases	0.587	0.413	0.000
Y49.2 Other and unspecified antidepressants	0.586	0.414	0.000
V10-V19 Pedal cyclist injured in transport accident	0.585	0.415	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.583	0.417	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.583	0.417	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.582	0.418	0.000
Y46.8 Antispasticity drugs	0.582	0.418	0.000
Y46.7 Anti-Parkinsonism drugs	0.582	0.418	0.000
Y46.6 Other and unspecified antiepileptics	0.582	0.418	0.000
Y46.5 Valproic acid	0.582	0.418	0.000
Y46.3 Deoxybarbiturates	0.582	0.418	0.000
Y46.2 Hydantoin derivatives	0.582	0.418	0.000
Y46.1 Oxazolidinediones	0.582	0.418	0.000
Y46.0 Succinimides	0.582	0.418	0.000
G72 Other myopathies	0.582	0.418	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.581	0.419	0.000
J17 Pneumonia in diseases classified elsewhere	0.580	0.420	0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.580	0.420	0.000
J12 Viral pneumonia, not elsewhere classified	0.580	0.420	0.000
J09 Influenza due to certain identified influenza virus	0.580	0.420	0.000
G90.2 Horner's syndrome	0.580	0.420	0.000
R01.2 Other cardiac sounds	0.579	0.420	0.000
T93.1 Sequelae of fracture of femur	0.577	0.423	0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.576	0.424	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.575	0.425	0.000
E78.5 Hyperlipidaemia, unspecified	0.575	0.425	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.575	0.425	0.000
E66 Obesity	0.575	0.425	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.573	0.427	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.573	0.427	0.000
A60 Anogenital herpesviral [herpes simplex] infections	0.571	0.429	0.000
A59 Trichomoniasis	0.571	0.429	0.000
A56 Other sexually transmitted chlamydial diseases	0.571	0.429	0.000
A54 Gonococcal infection	0.571	0.429	0.000
A53 Other and unspecified syphilis	0.571	0.429	0.000
A52 Late syphilis	0.571	0.429	0.000
A51 Early syphilis	0.571	0.429	0.000
A50 Congenital syphilis	0.571	0.429	0.000
A64 Unspecified sexually transmitted disease	0.571	0.429	0.000
A58 Granuloma inguinale	0.571	0.429	0.000
A57 Chancroid	0.571	0.429	0.000
A55 Chlamydial lymphogranuloma (venereum)	0.571	0.429	0.000
J39.9 Disease of upper respiratory tract, unspecified	0.570	0.430	0.000
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified	0.570	0.430	0.000
J39.1 Other abscess of pharynx	0.570	0.430	0.000
J39.0 Retropharyngeal and parapharyngeal abscess	0.570	0.430	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.570	0.430	0.000
G30.9 Alzheimer's disease, unspecified	0.570	0.430	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.570	0.430	0.000
J03 Acute tonsillitis	0.570	0.430	0.000
I87 Other disorders of veins	0.569	0.430	0.000
A30-A49 Other bacterial diseases	0.568	0.432	0.000
G60 Hereditary and idiopathic neuropathy	0.568	0.432	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.568	0.432	0.000
G71 Primary disorders of muscles	0.568	0.432	0.000
G81 Hemiplegia	0.567	0.433	0.000
Y44 Agents primarily affecting blood constituents	0.566	0.434	0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.565	0.434	0.000
X47 Accidental poisoning by and exposure to other gases and vapours	0.565	0.435	0.000
S80-S89 Injuries to the knee and lower leg	0.565	0.435	0.000
R25.1 Tremor, unspecified	0.564	0.436	0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.564	0.436	0.000
I82.8 Embolism and thrombosis of other specified veins	0.564	0.436	0.000
Q00-Q07 Congenital malformations of the nervous system	0.563	0.437	0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.562	0.438	0.000
G91 Hydrocephalus	0.562	0.438	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.562	0.438	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.561	0.439	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.561	0.439	0.000
Y53.7 Emetics	0.561	0.439	0.000
Y53.6 Antidiarrhoeal drugs	0.561	0.439	0.000
Y53.5 Digestants	0.561	0.439	0.000
Y53.4 Other laxatives	0.561	0.439	0.000
Y53.3 Saline and osmotic laxatives	0.561	0.439	0.000
Y53.2 Stimulant laxatives	0.561	0.439	0.000
Y53.0 Histamine H2-receptor antagonists	0.561	0.439	0.000
T11 Other injuries of upper limb, level unspecified	0.561	0.439	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.561	0.439	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.561	0.439	0.000
J60-J70 Lung diseases due to external agents	0.560	0.440	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.560	0.440	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.559	0.441	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.559	0.441	0.000
Y52.7 Peripheral vasodilators	0.559	0.441	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.559	0.441	0.000
Y52.1 Calcium-channel blockers	0.559	0.441	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.559	0.441	0.000
G80 Infantile cerebral palsy	0.559	0.441	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.558	0.441	0.000
Y57.9 Drug or medicament, unspecified	0.557	0.443	0.000
T93.2 Sequelae of other fractures of lower limb	0.557	0.443	0.000
S64.4 Injury of digital nerve of other finger	0.557	0.443	0.000
S64.1 Injury of median nerve at wrist and hand level	0.556	0.444	0.000
R47 Speech disturbances, not elsewhere classified	0.555	0.444	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.555	0.444	0.000
S62.5 Fracture of thumb	0.555	0.445	0.000
B35.9 Dermatophytosis, unspecified	0.554	0.445	0.000
B35.8 Other dermatophytoses	0.554	0.445	0.000
B35.5 Tinea imbricata	0.554	0.445	0.000
B35.4 Tinea corporis	0.554	0.445	0.000
B35.2 Tinea manuum	0.554	0.445	0.000
B35.1 Tinea unguium	0.554	0.445	0.000
B35.0 Tinea barbae and tinea capitis	0.554	0.445	0.000
S59 Other and unspecified injuries of forearm	0.554	0.445	0.000
S58 Traumatic amputation of forearm	0.554	0.445	0.000
S57 Crushing injury of forearm	0.554	0.445	0.000
S55 Injury of blood vessels at forearm level	0.554	0.445	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.554	0.445	0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.553	0.447	0.000
H60-H62 Diseases of external ear	0.552	0.448	0.000
B00 Herpesviral [herpes simplex] infections	0.552	0.448	0.000
E40-E46 Malnutrition	0.551	0.448	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.551	0.449	0.000
Q35-Q37 Cleft lip and cleft palate	0.551	0.449	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.551	0.449	0.000
J38.0 Paralysis of vocal cords and larynx	0.551	0.449	0.000
B34 Viral infection of unspecified site	0.550	0.449	0.000
Y43 Primarily systemic agents	0.550	0.449	0.000
J42 Unspecified chronic bronchitis	0.550	0.450	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.550	0.450	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.550	0.450	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.550	0.450	0.000
T93.0 Sequelae of open wound of lower limb	0.550	0.450	0.000
G30.0 Alzheimer's disease with early onset	0.549	0.451	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.549	0.451	0.000
Q80-Q89 Other congenital malformations	0.549	0.451	0.000
J32.2 Chronic ethmoidal sinusitis	0.548	0.452	0.000
S90 Superficial injury of ankle and foot	0.548	0.452	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.548	0.452	0.000
S00-S09 Injuries to the head	0.548	0.452	0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.547	0.452	0.000
R22.2 Localised swelling, mass and lump, trunk	0.546	0.454	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations