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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3744064
log Bayes Factor = 4.44478
Chromosome 17   position 75,211,208  (GRCh37) Explore rs3744064 on Ensembl!
Variant rs3744064 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
# Top node
0.999 0.001 0.000
M23 Internal derangement of knee
0.995 0.005 0.000
Chapter IX Diseases of the circulatory system
0.994 0.006 0.000
I30-I52 Other forms of heart disease
0.994 0.006 0.000
Chapter VI Diseases of the nervous system
0.992 0.008 0.000
Chapter I Certain infectious and parasitic diseases
0.988 0.012 0.000
I51 Complications and ill-defined descriptions of heart disease
0.982 0.018 0.000
G90-G99 Other disorders of the nervous system
0.981 0.019 0.000
B95-B98 Bacterial, viral and other infectious agents
0.980 0.020 0.000
Chapter V Mental and behavioural disorders
0.976 0.024 0.000
M20 Acquired deformities of fingers and toes
0.975 0.025 0.000
I50 Heart failure
0.967 0.033 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.963 0.037 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.957 0.043 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.956 0.044 0.000
M15-M19 Arthrosis
0.954 0.046 0.000
I51.8 Other ill-defined heart diseases
0.954 0.046 0.000
M23.3 Other meniscus derangements
0.950 0.050 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.948 0.052 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.946 0.054 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.942 0.058 0.000
M24 Other specific joint derangements
0.941 0.059 0.000
M70-M79 Other soft tissue disorders
0.939 0.061 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.938 0.062 0.000
Chapter XX External causes of morbidity and mortality
0.937 0.063 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.930 0.070 0.000
M20.2 Hallux rigidus
0.929 0.071 0.000
I50.0 Congestive heart failure
0.925 0.075 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.922 0.078 0.000
M16 Coxarthrosis [arthrosis of hip]
0.910 0.090 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.908 0.092 0.000
I05-I09 Chronic rheumatic heart diseases
0.895 0.105 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.894 0.106 0.000
F30-F39 Mood [affective] disorders
0.894 0.106 0.000
I42 Cardiomyopathy
0.892 0.108 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.892 0.108 0.000
M45-M49 Spondylopathies
0.888 0.112 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.886 0.114 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.885 0.115 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.884 0.116 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.872 0.128 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.871 0.129 0.000
I51.7 Cardiomegaly
0.871 0.129 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.869 0.131 0.000
M34 Systemic sclerosis
0.868 0.132 0.000
M20.1 Hallux valgus (acquired)
0.860 0.140 0.000
Y86 Sequelae of other accidents
0.855 0.145 0.000
G30-G32 Other degenerative diseases of the nervous system
0.852 0.148 0.000
I50.9 Heart failure, unspecified
0.852 0.148 0.000
M16.1 Other primary coxarthrosis
0.852 0.148 0.000
L90 Atrophic disorders of skin
0.851 0.149 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.843 0.157 0.000
M47 Spondylosis
0.842 0.158 0.000
I71 Aortic aneurysm and dissection
0.838 0.162 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.837 0.163 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.836 0.164 0.000
M23.8 Other internal derangements of knee
0.836 0.164 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.836 0.164 0.000
M79.6 Pain in limb
0.835 0.165 0.000
G95 Other diseases of spinal cord
0.830 0.170 0.000
M79.0 Rheumatism, unspecified
0.826 0.174 0.000
I74 Arterial embolism and thrombosis
0.821 0.179 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.821 0.179 0.000
M24.1 Other articular cartilage disorders
0.817 0.183 0.000
G20-G26 Extrapyramidal and movement disorders
0.815 0.185 0.000
M65-M68 Disorders of synovium and tendon
0.814 0.186 0.000
I35 Nonrheumatic aortic valve disorders
0.813 0.187 0.000
M20.5 Other deformities of toe(s) (acquired)
0.813 0.187 0.000
M23.4 Loose body in knee
0.811 0.189 0.000
F32 Depressive episode
0.808 0.192 0.000
M17 Gonarthrosis [arthrosis of knee]
0.805 0.195 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.805 0.195 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.804 0.196 0.000
M16.0 Primary coxarthrosis, bilateral
0.804 0.196 0.000
F10.1 Harmful use
0.803 0.197 0.000
M47.9 Spondylosis, unspecified
0.799 0.201 0.000
I33 Acute and subacute endocarditis
0.799 0.201 0.000
L89 Decubitus ulcer
0.799 0.201 0.000
L90.5 Scar conditions and fibrosis of skin
0.795 0.205 0.000
V20-V29 Motorcycle rider injured in transport accident
0.793 0.207 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.793 0.207 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.793 0.207 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.792 0.208 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.789 0.211 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.787 0.212 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.785 0.215 0.000
Chapter XXII Codes for special purposes
0.784 0.216 0.000
M24.0 Loose body in joint
0.783 0.217 0.000
I08 Multiple valve diseases
0.783 0.217 0.000
G91 Hydrocephalus
0.779 0.221 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.778 0.222 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.777 0.223 0.000
G93 Other disorders of brain
0.773 0.227 0.000
M20.4 Other hammer toe(s) (acquired)
0.773 0.227 0.000
I46 Cardiac arrest
0.771 0.229 0.000
I45 Other conduction disorders
0.767 0.233 0.000
L40-L45 Papulosquamous disorders
0.760 0.240 0.000
M91-M94 Chondropathies
0.760 0.240 0.000
M79.1 Myalgia
0.756 0.244 0.000
I51.4 Myocarditis, unspecified
0.755 0.245 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.751 0.249 0.000
I31 Other diseases of pericardium
0.751 0.249 0.000
I07 Rheumatic tricuspid valve diseases
0.750 0.250 0.000
A80-A89 Viral infections of the central nervous system
0.749 0.251 0.000
M17.1 Other primary gonarthrosis
0.747 0.253 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.747 0.253 0.000
F17.1 Harmful use
0.747 0.253 0.000
I42.0 Dilated cardiomyopathy
0.745 0.254 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.744 0.256 0.000
I73 Other peripheral vascular diseases
0.743 0.257 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.742 0.258 0.000
I30 Acute pericarditis
0.740 0.260 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.740 0.260 0.000
M18 Arthrosis of first carpometacarpal joint
0.739 0.261 0.000
M21 Other acquired deformities of limbs
0.738 0.262 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.737 0.263 0.000
G70-G73 Diseases of myoneural junction and muscle
0.737 0.263 0.000
L94 Other localised connective tissue disorders
0.736 0.264 0.000
I74.5 Embolism and thrombosis of iliac artery
0.735 0.265 0.000
L50-L54 Urticaria and erythema
0.735 0.265 0.000
F10.3 Withdrawal state
0.733 0.267 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.733 0.267 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.730 0.270 0.000
M79.64 Pain in limb (Hand)
0.729 0.270 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.729 0.271 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.729 0.271 0.000
F10.0 Acute intoxication
0.728 0.272 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.728 0.272 0.000
F10.2 Dependence syndrome
0.727 0.273 0.000
B35-B49 Mycoses
0.727 0.273 0.000
L60-L75 Disorders of skin appendages
0.726 0.274 0.000
M31 Other necrotising vasculopathies
0.725 0.274 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.725 0.275 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.725 0.275 0.000
I77 Other disorders of arteries and arterioles
0.724 0.276 0.000
M34.9 Systemic sclerosis, unspecified
0.724 0.276 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.724 0.276 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.723 0.277 0.000
M40-M43 Deforming dorsopathies
0.723 0.277 0.000
L83 Acanthosis nigricans
0.722 0.278 0.000
M79.67 Pain in limb (Ankle and foot)
0.722 0.278 0.000
X60-X84 Intentional self-harm
0.721 0.279 0.000
F31 Bipolar affective disorder
0.720 0.280 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.720 0.280 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.720 0.280 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.719 0.281 0.000
M50-M54 Other dorsopathies
0.718 0.282 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.718 0.282 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
M79.8 Other specified soft tissue disorders
0.716 0.284 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.716 0.284 0.000
I34 Nonrheumatic mitral valve disorders
0.714 0.286 0.000
M79.5 Residual foreign body in soft tissue
0.714 0.286 0.000
M23.9 Internal derangement of knee, unspecified
0.713 0.286 0.000
M23.1 Discoid meniscus (congenital)
0.713 0.286 0.000
M23.0 Cystic meniscus
0.713 0.286 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.713 0.287 0.000
I00-I02 Acute rheumatic fever
0.713 0.287 0.000
I52 Other heart disorders in diseases classified elsewhere
0.713 0.287 0.000
I48 Atrial fibrillation and flutter
0.713 0.287 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.713 0.287 0.000
I41 Myocarditis in diseases classified elsewhere
0.713 0.287 0.000
I40 Acute myocarditis
0.713 0.287 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.713 0.287 0.000
I37 Pulmonary valve disorders
0.713 0.287 0.000
I36 Nonrheumatic tricuspid valve disorders
0.713 0.287 0.000
I32 Pericarditis in diseases classified elsewhere
0.713 0.287 0.000
M16.3 Other dysplastic coxarthrosis
0.711 0.289 0.000
M79.63 Pain in limb (Forearm)
0.709 0.290 0.000
B99-B99 Other infectious diseases
0.709 0.291 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.709 0.291 0.000
B65-B83 Helminthiases
0.709 0.291 0.000
B50-B64 Protozoal diseases
0.709 0.291 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.709 0.291 0.000
A75-A79 Rickettsioses
0.709 0.291 0.000
A70-A74 Other diseases caused by chlamydiae
0.709 0.291 0.000
A65-A69 Other spirochaetal diseases
0.709 0.291 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.709 0.291 0.000
A20-A28 Certain zoonotic bacterial diseases
0.709 0.291 0.000
A15-A19 Tuberculosis
0.709 0.291 0.000
I08.0 Disorders of both mitral and aortic valves
0.708 0.292 0.000
M34.8 Other forms of systemic sclerosis
0.707 0.293 0.000
B00 Herpesviral [herpes simplex] infections
0.707 0.293 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.706 0.294 0.000
I51.9 Heart disease, unspecified
0.706 0.294 0.000
I42.2 Other hypertrophic cardiomyopathy
0.706 0.294 0.000
I51.6 Cardiovascular disease, unspecified
0.704 0.296 0.000
I51.5 Myocardial degeneration
0.704 0.296 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.704 0.296 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.704 0.296 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.704 0.296 0.000
I51.0 Cardiac septal defect, acquired
0.704 0.296 0.000
L85 Other epidermal thickening
0.704 0.296 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.703 0.296 0.000
G96 Other disorders of central nervous system
0.703 0.296 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.703 0.296 0.000
G90 Disorders of autonomic nervous system
0.703 0.296 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.703 0.296 0.000
G92 Toxic encephalopathy
0.703 0.296 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.703 0.297 0.000
M80-M85 Disorders of bone density and structure
0.703 0.297 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.701 0.299 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.700 0.300 0.000
F70-F79 Mental retardation
0.700 0.300 0.000
I49 Other cardiac arrhythmias
0.699 0.301 0.000
I35.0 Aortic (valve) stenosis
0.694 0.306 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.693 0.307 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.693 0.307 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.693 0.307 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.692 0.308 0.000
I72 Other aneurysm
0.691 0.309 0.000
L10-L14 Bullous disorders
0.690 0.310 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.690 0.310 0.000
M86-M90 Other osteopathies
0.690 0.310 0.000
M23.5 Chronic instability of knee
0.688 0.312 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.688 0.312 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.687 0.313 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.687 0.313 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.687 0.313 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.686 0.313 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.686 0.313 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.686 0.313 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.686 0.313 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.686 0.313 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.686 0.313 0.000
F11 Mental and behavioural disorders due to use of opioids
0.686 0.313 0.000
Q60-Q64 Congenital malformations of the urinary system
0.686 0.314 0.000
F80-F89 Disorders of psychological development
0.686 0.314 0.000
G24 Dystonia
0.686 0.314 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.686 0.314 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.686 0.314 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.686 0.314 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.686 0.314 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.686 0.314 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.684 0.316 0.000
M15 Polyarthrosis
0.684 0.316 0.000
M77 Other enthesopathies
0.683 0.317 0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.683 0.317 0.000
M35 Other systemic involvement of connective tissue
0.682 0.317 0.000
F99-F99 Unspecified mental disorder
0.681 0.319 0.000
M23.37 Other meniscus derangements-Capsular lig
0.681 0.319 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.681 0.319 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.681 0.319 0.000
M65 Synovitis and tenosynovitis
0.680 0.320 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.679 0.320 0.000
B25-B34 Other viral diseases
0.679 0.320 0.000
M23.49 Loose body in knee-Unspec lig/men
0.679 0.321 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.678 0.322 0.000
B15-B19 Viral hepatitis
0.676 0.324 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.676 0.324 0.000
G95.1 Vascular myelopathies
0.676 0.324 0.000
M05-M14 Inflammatory polyarthropathies
0.675 0.325 0.000
F12.1 Harmful use
0.675 0.325 0.000
M24.9 Joint derangement, unspecified
0.674 0.325 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.674 0.325 0.000
M24.7 Protrusio acetabuli
0.674 0.325 0.000
M24.6 Ankylosis of joint
0.674 0.325 0.000
M24.5 Contracture of joint
0.674 0.325 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.674 0.325 0.000
M24.2 Disorder of ligament
0.674 0.325 0.000
I78 Diseases of capillaries
0.674 0.325 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.674 0.326 0.000
Y85 Sequelae of transport accidents
0.674 0.326 0.000
M71 Other bursopathies
0.674 0.326 0.000
M76 Enthesopathies of lower limb, excluding foot
0.673 0.326 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.673 0.326 0.000
Y35-Y36 Legal intervention and operations of war
0.672 0.328 0.000
Y10-Y34 Event of undetermined intent
0.672 0.328 0.000
Y00-Y09 Assault
0.672 0.328 0.000
X85-X99 Assault
0.672 0.328 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.672 0.328 0.000
X50-X57 Overexertion, travel and privation
0.672 0.328 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.672 0.328 0.000
X30-X39 Exposure to forces of nature
0.672 0.328 0.000
X20-X29 Contact with venomous animals and plants
0.672 0.328 0.000
X10-X19 Contact with heat and hot substances
0.672 0.328 0.000
X00-X09 Exposure to smoke, fire and flames
0.672 0.328 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.672 0.328 0.000
W75-W84 Other accidental threats to breathing
0.672 0.328 0.000
W65-W74 Accidental drowning and submersion
0.672 0.328 0.000
W50-W64 Exposure to animate mechanical forces
0.672 0.328 0.000
V98-V99 Other and unspecified transport accidents
0.672 0.328 0.000
V95-V97 Air and space transport accidents
0.672 0.328 0.000
V90-V94 Water transport accidents
0.672 0.328 0.000
V80-V89 Other land transport accidents
0.672 0.328 0.000
V70-V79 Bus occupant injured in transport accident
0.672 0.328 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.672 0.328 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.672 0.328 0.000
V40-V49 Car occupant injured in transport accident
0.672 0.328 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.672 0.328 0.000
V01-V09 Pedestrian injured in transport accident
0.672 0.328 0.000
F32.1 Moderate depressive episode
0.671 0.328 0.000
G95.2 Cord compression, unspecified
0.671 0.329 0.000
F32.9 Depressive episode, unspecified
0.671 0.329 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.670 0.329 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.670 0.330 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.669 0.330 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.669 0.331 0.000
I42.8 Other cardiomyopathies
0.669 0.331 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.668 0.332 0.000
F60-F69 Disorders of adult personality and behaviour
0.667 0.332 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.667 0.333 0.000
L93 Lupus erythematosus
0.667 0.333 0.000
L87 Transepidermal elimination disorders
0.667 0.333 0.000
L88 Pyoderma gangrenosum
0.667 0.333 0.000
L86 Keratoderma in diseases classified elsewhere
0.667 0.333 0.000
L80 Vitiligo
0.667 0.333 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.667 0.333 0.000
A30-A49 Other bacterial diseases
0.666 0.334 0.000
M47.1 Other spondylosis with myelopathy
0.666 0.334 0.000
M79.69 Pain in limb (Site unspecified)
0.664 0.336 0.000
I45.6 Preexcitation syndrome
0.662 0.338 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.661 0.339 0.000
M79.9 Soft tissue disorder, unspecified
0.661 0.339 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.661 0.339 0.000
M79.3 Panniculitis, unspecified
0.661 0.339 0.000
M79.2 Neuralgia and neuritis, unspecified
0.661 0.339 0.000
I73.0 Raynaud's syndrome
0.659 0.341 0.000
I33.0 Acute and subacute infective endocarditis
0.659 0.341 0.000
I50.1 Left ventricular failure
0.659 0.341 0.000
M79.7 Fibromyalgia
0.656 0.344 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.656 0.344 0.000
L40 Psoriasis
0.655 0.345 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.654 0.346 0.000
M50 Cervical disk disorders
0.654 0.346 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.654 0.346 0.000
Q00-Q07 Congenital malformations of the nervous system
0.654 0.346 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.652 0.348 0.000
M16.5 Other posttraumatic coxarthrosis
0.652 0.348 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.652 0.348 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.652 0.348 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.652 0.348 0.000
F10.9 Unspecified mental and behavioural disorder
0.651 0.349 0.000
F10.8 Other mental and behavioural disorders
0.651 0.349 0.000
F10.7 Residual and late-onset psychotic disorder
0.651 0.349 0.000
F10.6 Amnesic syndrome
0.651 0.349 0.000
F10.5 Psychotic disorder
0.651 0.349 0.000
F10.4 Withdrawal state with delirium
0.651 0.349 0.000
V10-V19 Pedal cyclist injured in transport accident
0.651 0.349 0.000
G30 Alzheimer's disease
0.651 0.349 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.651 0.349 0.000
I35.8 Other aortic valve disorders
0.647 0.353 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.647 0.353 0.000
I07.1 Tricuspid insufficiency
0.647 0.353 0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)
0.647 0.353 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.646 0.354 0.000
L20-L30 Dermatitis and eczema
0.645 0.354 0.000
G20 Parkinson's disease
0.645 0.355 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.642 0.357 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.642 0.358 0.000
I47 Paroxysmal tachycardia
0.642 0.358 0.000
I09 Other rheumatic heart diseases
0.641 0.359 0.000
I06 Rheumatic aortic valve diseases
0.641 0.359 0.000
M72 Fibroblastic disorders
0.641 0.359 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.641 0.359 0.000
F38 Other mood [affective] disorders
0.641 0.359 0.000
F34 Persistent mood [affective] disorders
0.641 0.359 0.000
F30 Manic episode
0.641 0.359 0.000
F39 Unspecified mood [affective] disorder
0.641 0.359 0.000
F33 Recurrent depressive disorder
0.640 0.360 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.639 0.360 0.000
I42.6 Alcoholic cardiomyopathy
0.639 0.360 0.000
I42.5 Other restrictive cardiomyopathy
0.639 0.360 0.000
I42.4 Endocardial fibroelastosis
0.639 0.360 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.639 0.360 0.000
Y89 Sequelae of other external causes
0.639 0.361 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.639 0.361 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.639 0.361 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.639 0.361 0.000
M47.2 Other spondylosis with radiculopathy
0.638 0.362 0.000
I70 Atherosclerosis
0.637 0.363 0.000
M49 Spondylopathies in diseases classified elsewhere
0.637 0.363 0.000
I31.3 Pericardial effusion (noninflammatory)
0.636 0.364 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.636 0.364 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.636 0.364 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.636 0.364 0.000
I42.9 Cardiomyopathy, unspecified
0.635 0.365 0.000
G51 Facial nerve disorders
0.635 0.365 0.000
Y88 Sequelae of surgical and medical care as external cause
0.633 0.367 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.633 0.367 0.000
Q80-Q89 Other congenital malformations
0.632 0.367 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.632 0.368 0.000
M46 Other inflammatory spondylopathies
0.632 0.368 0.000
M20.3 Other deformity of hallux (acquired)
0.632 0.368 0.000
G95.8 Other specified diseases of spinal cord
0.630 0.370 0.000
M24.07 Loose body in joint (Ankle and foot)
0.629 0.371 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.628 0.372 0.000
L71 Rosacea
0.628 0.372 0.000
M79.60 Pain in limb (Multiple sites)
0.628 0.372 0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.628 0.372 0.000
M16.7 Other secondary coxarthrosis
0.628 0.372 0.000
I35.1 Aortic (valve) insufficiency
0.627 0.373 0.000
B91 Sequelae of poliomyelitis
0.627 0.373 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.626 0.374 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.625 0.375 0.000
Q35-Q37 Cleft lip and cleft palate
0.625 0.375 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.625 0.375 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.625 0.375 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.625 0.375 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.624 0.375 0.000
G03 Meningitis due to other and unspecified causes
0.624 0.375 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.624 0.375 0.000
G00 Bacterial meningitis, not elsewhere classified
0.624 0.375 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.624 0.375 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.624 0.375 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.624 0.375 0.000
Q50-Q56 Congenital malformations of genital organs
0.624 0.376 0.000
G91.1 Obstructive hydrocephalus
0.623 0.377 0.000
L98.7 Excessive and redundant skin and subcutaneous tissue
0.623 0.377 0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.623 0.377 0.000
L98.5 Mucinosis of skin
0.623 0.377 0.000
L98.3 Eosinophilic cellulitis [Wells]
0.623 0.377 0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]
0.623 0.377 0.000
L98.1 Factitial dermatitis
0.623 0.377 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.622 0.378 0.000
M34.1 CR(E)ST syndrome
0.622 0.378 0.000
M34.0 Progressive systemic sclerosis
0.622 0.378 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.622 0.378 0.000
W00-W19 Falls
0.622 0.378 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.621 0.379 0.000
M24.02 Loose body in joint (Upper arm)
0.620 0.379 0.000
B49 Unspecified mycosis
0.620 0.380 0.000
M17.9 Gonarthrosis, unspecified
0.620 0.380 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.618 0.382 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.617 0.383 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.616 0.383 0.000
V23.4 Driver injured in traffic accident
0.616 0.384 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.616 0.384 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.615 0.385 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.614 0.386 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.614 0.386 0.000
G31.8 Other specified degenerative diseases of nervous system
0.613 0.387 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.611 0.389 0.000
I05 Rheumatic mitral valve diseases
0.611 0.389 0.000
G31.2 Degeneration of nervous system due to alcohol
0.611 0.389 0.000
L90.9 Atrophic disorder of skin, unspecified
0.610 0.390 0.000
L90.8 Other atrophic disorders of skin
0.610 0.390 0.000
L90.6 Striae atrophicae
0.610 0.390 0.000
L90.4 Acrodermatitis chronica atrophicans
0.610 0.390 0.000
L90.3 Atrophoderma of Pasini and Pierini
0.610 0.390 0.000
L90.2 Anetoderma of Jadassohn-Pellizzari
0.610 0.390 0.000
L90.1 Anetoderma of Schweninger-Buzzi
0.610 0.390 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.610 0.390 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.610 0.390 0.000
I38 Endocarditis, valve unspecified
0.609 0.391 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.609 0.391 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.608 0.392 0.000
L90.0 Lichen sclerosus et atrophicus
0.608 0.392 0.000
W20-W49 Exposure to inanimate mechanical forces
0.608 0.392 0.000
I46.0 Cardiac arrest with successful resuscitation
0.608 0.392 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.608 0.392 0.000
M17.3 Other posttraumatic gonarthrosis
0.607 0.393 0.000
F17.2 Dependence syndrome
0.607 0.393 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.607 0.393 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.607 0.393 0.000
M79.19 Myalgia (Site unspecified)
0.606 0.394 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.606 0.394 0.000
B02 Zoster [herpes zoster]
0.605 0.395 0.000
Y52 Agents primarily affecting the cardiovascular system
0.604 0.396 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.604 0.396 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.603 0.397 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.603 0.397 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.601 0.399 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.601 0.399 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.601 0.399 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.601 0.399 0.000
I71.0 Dissection of aorta [any part]
0.601 0.399 0.000
B06 Rubella [German measles]
0.600 0.400 0.000
B05 Measles
0.600 0.400 0.000
B01 Varicella [chickenpox]
0.600 0.400 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.600 0.400 0.000
B04 Monkeypox
0.600 0.400 0.000
B03 Smallpox
0.600 0.400 0.000
F17.9 Unspecified mental and behavioural disorder
0.600 0.400 0.000
F17.8 Other mental and behavioural disorders
0.600 0.400 0.000
F17.7 Residual and late-onset psychotic disorder
0.600 0.400 0.000
F17.6 Amnesic syndrome
0.600 0.400 0.000
F17.5 Psychotic disorder
0.600 0.400 0.000
F17.4 Withdrawal state with delirium
0.600 0.400 0.000
F17.3 Withdrawal state
0.600 0.400 0.000
F17.0 Acute intoxication
0.600 0.400 0.000
M23.87 Other internal derangements of knee (Capsular ligament)
0.599 0.401 0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.599 0.401 0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)
0.599 0.401 0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.599 0.401 0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.599 0.401 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.599 0.401 0.000
M79.68 Pain in limb (Other)
0.598 0.401 0.000
M79.61 Pain in limb (Shoulder region)
0.598 0.401 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.597 0.403 0.000
L94.2 Calcinosis cutis
0.596 0.404 0.000
G95.0 Syringomyelia and syringobulbia
0.595 0.404 0.000
B07 Viral warts
0.595 0.404 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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