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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4374681
log Bayes Factor = 5.49218
Chromosome 4   position 1,566,164  (GRCh37) Explore rs4374681 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I25.2 Old myocardial infarction
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.986 0.014 0.000
I30-I52 Other forms of heart disease
0.985 0.015 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.980 0.020 0.000
I77 Other disorders of arteries and arterioles
0.976 0.024 0.000
I25.1 Atherosclerotic heart disease
0.973 0.027 0.000
I21 Acute myocardial infarction
0.971 0.029 0.000
I47 Paroxysmal tachycardia
0.971 0.029 0.000
I05-I09 Chronic rheumatic heart diseases
0.968 0.032 0.000
I77.1 Stricture of artery
0.964 0.036 0.000
I21.9 Acute myocardial infarction, unspecified
0.960 0.040 0.000
I47.2 Ventricular tachycardia
0.948 0.052 0.000
I08 Multiple valve diseases
0.939 0.061 0.000
I44 Atrioventricular and left bundle-branch block
0.920 0.080 0.000
I37 Pulmonary valve disorders
0.899 0.101 0.000
I51 Complications and ill-defined descriptions of heart disease
0.896 0.104 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.891 0.109 0.000
I47.1 Supraventricular tachycardia
0.881 0.119 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.872 0.128 0.000
I74 Arterial embolism and thrombosis
0.871 0.129 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.867 0.133 0.000
I35 Nonrheumatic aortic valve disorders
0.863 0.137 0.000
I44.0 Atrioventricular block, first degree
0.859 0.141 0.000
I37.1 Pulmonary valve insufficiency
0.837 0.163 0.000
I35.0 Aortic (valve) stenosis
0.836 0.164 0.000
I49 Other cardiac arrhythmias
0.827 0.173 0.000
I44.2 Atrioventricular block, complete
0.825 0.175 0.000
I77.8 Other specified disorders of arteries and arterioles
0.823 0.177 0.000
I25.5 Ischaemic cardiomyopathy
0.820 0.180 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.815 0.185 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.815 0.185 0.000
I51.7 Cardiomegaly
0.811 0.189 0.000
I77.6 Arteritis, unspecified
0.801 0.199 0.000
I27 Other pulmonary heart diseases
0.799 0.200 0.000
I08.9 Multiple valve disease, unspecified
0.799 0.201 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.791 0.209 0.000
I24 Other acute ischaemic heart diseases
0.789 0.211 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.788 0.212 0.000
I05 Rheumatic mitral valve diseases
0.785 0.215 0.000
I36 Nonrheumatic tricuspid valve disorders
0.776 0.224 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.772 0.228 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.747 0.253 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.743 0.257 0.000
I70 Atherosclerosis
0.741 0.259 0.000
I44.1 Atrioventricular block, second degree
0.740 0.260 0.000
I46 Cardiac arrest
0.736 0.264 0.000
I28 Other diseases of pulmonary vessels
0.734 0.266 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.731 0.269 0.000
I09 Other rheumatic heart diseases
0.730 0.270 0.000
I27.2 Other secondary pulmonary hypertension
0.723 0.277 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.715 0.285 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.712 0.288 0.000
I22 Subsequent myocardial infarction
0.709 0.291 0.000
I52 Other heart disorders in diseases classified elsewhere
0.706 0.294 0.000
I48 Atrial fibrillation and flutter
0.706 0.294 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.706 0.294 0.000
I41 Myocarditis in diseases classified elsewhere
0.706 0.294 0.000
I40 Acute myocarditis
0.706 0.294 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.706 0.294 0.000
I32 Pericarditis in diseases classified elsewhere
0.706 0.294 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.705 0.295 0.000
I49.3 Ventricular premature depolarisation
0.702 0.298 0.000
I77.5 Necrosis of artery
0.700 0.300 0.000
I77.4 Coeliac artery compression syndrome
0.700 0.300 0.000
I77.3 Arterial fibromuscular dysplasia
0.700 0.300 0.000
I77.2 Rupture of artery
0.700 0.300 0.000
I77.0 Arteriovenous fistula, acquired
0.700 0.300 0.000
I74.8 Embolism and thrombosis of other arteries
0.699 0.301 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.696 0.304 0.000
I51.8 Other ill-defined heart diseases
0.696 0.304 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.694 0.306 0.000
I06 Rheumatic aortic valve diseases
0.694 0.306 0.000
I08.8 Other multiple valve diseases
0.693 0.307 0.000
I25.3 Aneurysm of heart
0.684 0.316 0.000
I49.8 Other specified cardiac arrhythmias
0.683 0.317 0.000
I49.4 Other and unspecified premature depolarisation
0.677 0.323 0.000
I33 Acute and subacute endocarditis
0.673 0.326 0.000
I47.0 Reentry ventricular arrhythmia
0.672 0.328 0.000
I27.0 Primary pulmonary hypertension
0.667 0.333 0.000
I44.5 Left posterior fascicular block
0.659 0.341 0.000
I44.4 Left anterior fascicular block
0.659 0.341 0.000
I72 Other aneurysm
0.658 0.342 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.657 0.343 0.000
I51.9 Heart disease, unspecified
0.649 0.351 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.645 0.355 0.000
I37.9 Pulmonary valve disorder, unspecified
0.644 0.355 0.000
I37.8 Other pulmonary valve disorders
0.644 0.355 0.000
I37.2 Pulmonary valve stenosis with insufficiency
0.644 0.355 0.000
I37.0 Pulmonary valve stenosis
0.644 0.355 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.644 0.356 0.000
I51.6 Cardiovascular disease, unspecified
0.642 0.358 0.000
I51.5 Myocardial degeneration
0.642 0.358 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.642 0.358 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.642 0.358 0.000
I08.0 Disorders of both mitral and aortic valves
0.633 0.367 0.000
I05.9 Mitral valve disease, unspecified
0.630 0.370 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.629 0.371 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.627 0.373 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.625 0.375 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.624 0.375 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.624 0.375 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.624 0.375 0.000
I28.8 Other specified diseases of pulmonary vessels
0.621 0.379 0.000
I24.1 Dressler's syndrome
0.618 0.382 0.000
I51.0 Cardiac septal defect, acquired
0.614 0.386 0.000
I07 Rheumatic tricuspid valve diseases
0.611 0.388 0.000
Z82.3 Family history of stroke
0.610 0.390 0.000
I46.0 Cardiac arrest with successful resuscitation
0.610 0.390 0.000
I51.4 Myocarditis, unspecified
0.609 0.391 0.000
I05.0 Mitral stenosis
0.606 0.394 0.000
I95 Hypotension
0.606 0.394 0.000
I44.6 Other and unspecified fascicular block
0.603 0.396 0.000
I99 Other and unspecified disorders of circulatory system
0.596 0.404 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.594 0.406 0.000
I49.2 Junctional premature depolarisation
0.593 0.407 0.000
I30 Acute pericarditis
0.587 0.413 0.000
I49.5 Sick sinus syndrome
0.582 0.418 0.000
I49.0 Ventricular fibrillation and flutter
0.580 0.420 0.000
I27.1 Kyphoscoliotic heart disease
0.573 0.427 0.000
I27.8 Other specified pulmonary heart diseases
0.571 0.428 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.570 0.430 0.000
I05.8 Other mitral valve diseases
0.563 0.437 0.000
I05.1 Rheumatic mitral insufficiency
0.563 0.437 0.000
I38 Endocarditis, valve unspecified
0.560 0.440 0.000
I09.9 Rheumatic heart disease, unspecified
0.559 0.440 0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.556 0.444 0.000
I36.8 Other nonrheumatic tricuspid valve disorders
0.556 0.444 0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.556 0.444 0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.556 0.444 0.000
I74.5 Embolism and thrombosis of iliac artery
0.556 0.444 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.552 0.448 0.000
I05.2 Mitral stenosis with insufficiency
0.552 0.448 0.000
I26 Pulmonary embolism
0.551 0.449 0.000
I97.1 Other functional disturbances following cardiac surgery
0.548 0.452 0.000
I35.1 Aortic (valve) insufficiency
0.548 0.452 0.000
I95.9 Hypotension, unspecified
0.546 0.454 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.546 0.454 0.000
I44.3 Other and unspecified atrioventricular block
0.536 0.464 0.000
I70.9 Generalised and unspecified atherosclerosis
0.532 0.468 0.000
I70.8 Atherosclerosis of other arteries
0.532 0.468 0.000
I70.1 Atherosclerosis of renal artery
0.532 0.468 0.000
I70.0 Atherosclerosis of aorta
0.532 0.468 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.528 0.472 0.000
I46.1 Sudden cardiac death, so described
0.527 0.472 0.000
I78 Diseases of capillaries
0.527 0.472 0.000
I49.1 Atrial premature depolarisation
0.527 0.473 0.000
I28.9 Disease of pulmonary vessels, unspecified
0.526 0.474 0.000
I28.1 Aneurysm of pulmonary artery
0.526 0.474 0.000
I28.0 Arteriovenous fistula of pulmonary vessels
0.526 0.474 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.524 0.476 0.000
I79.1 Aortitis in diseases classified elsewhere
0.524 0.476 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.524 0.476 0.000
I09.8 Other specified rheumatic heart diseases
0.523 0.477 0.000
I09.2 Chronic rheumatic pericarditis
0.523 0.477 0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.523 0.477 0.000
I09.0 Rheumatic myocarditis
0.523 0.477 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.522 0.478 0.000
I23.8 Other current complications following acute myocardial infarction
0.514 0.486 0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.514 0.486 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.514 0.486 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.514 0.486 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.514 0.486 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.514 0.486 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.514 0.486 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.514 0.486 0.000
I02 Rheumatic chorea
0.513 0.487 0.000
I01 Rheumatic fever with heart involvement
0.513 0.487 0.000
I00 Rheumatic fever without mention of heart involvement
0.513 0.487 0.000
I32.8 Pericarditis in other diseases classified elsewhere
0.506 0.493 0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.506 0.493 0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.506 0.493 0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.506 0.493 0.000
I39.4 Multiple valve disorders in diseases classified elsewhere
0.506 0.493 0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.506 0.493 0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.506 0.493 0.000
I39.1 Aortic valve disorders in diseases classified elsewhere
0.506 0.493 0.000
I39.0 Mitral valve disorders in diseases classified elsewhere
0.506 0.493 0.000
I40.9 Acute myocarditis, unspecified
0.506 0.493 0.000
I40.8 Other acute myocarditis
0.506 0.493 0.000
I40.1 Isolated myocarditis
0.506 0.493 0.000
I40.0 Infective myocarditis
0.506 0.493 0.000
I41.8 Myocarditis in other diseases classified elsewhere
0.506 0.493 0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.506 0.493 0.000
I41.1 Myocarditis in viral diseases classified elsewhere
0.506 0.493 0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.506 0.493 0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.506 0.493 0.000
I43.2 Cardiomyopathy in nutritional diseases
0.506 0.493 0.000
I43.1 Cardiomyopathy in metabolic diseases
0.506 0.493 0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.506 0.493 0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.506 0.493 0.000
I48.4 Atypical atrial flutter
0.506 0.493 0.000
I48.3 Typical atrial flutter
0.506 0.493 0.000
I48.2 Chronic atrial fibrillation
0.506 0.493 0.000
I48.1 Persistent atrial fibrillation
0.506 0.493 0.000
I48.0 Paroxysmal atrial fibrillation
0.506 0.493 0.000
I52.8 Other heart disorders in other diseases classified elsewhere
0.506 0.493 0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.506 0.493 0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.506 0.493 0.000
I06.9 Rheumatic aortic valve disease, unspecified
0.497 0.502 0.000
I06.8 Other rheumatic aortic valve diseases
0.497 0.502 0.000
I06.2 Rheumatic aortic stenosis with insufficiency
0.497 0.502 0.000
I06.1 Rheumatic aortic insufficiency
0.497 0.502 0.000
I06.0 Rheumatic aortic stenosis
0.497 0.502 0.000
M65-M68 Disorders of synovium and tendon
0.495 0.505 0.000
I35.9 Aortic valve disorder, unspecified
0.493 0.506 0.000
I72.4 Aneurysm of artery of lower extremity
0.493 0.506 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.489 0.511 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.489 0.511 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.484 0.516 0.000
I33.9 Acute endocarditis, unspecified
0.483 0.517 0.000
M65 Synovitis and tenosynovitis
0.480 0.520 0.000
M67 Other disorders of synovium and tendon
0.479 0.521 0.000
M80-M85 Disorders of bone density and structure
0.477 0.523 0.000
# Top node
0.476 0.524 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.475 0.524 0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.474 0.526 0.000
I27.9 Pulmonary heart disease, unspecified
0.473 0.526 0.000
I72.9 Aneurysm of unspecified site
0.472 0.528 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.472 0.528 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.472 0.528 0.000
I72.2 Aneurysm of renal artery
0.472 0.528 0.000
I72.1 Aneurysm of artery of upper extremity
0.472 0.528 0.000
I72.8 Aneurysm of other specified arteries
0.470 0.530 0.000
I44.7 Left bundle-branch block, unspecified
0.470 0.530 0.000
I95.0 Idiopathic hypotension
0.470 0.530 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.469 0.531 0.000
Chapter VII Diseases of the eye and adnexa
0.468 0.532 0.000
I95.8 Other hypotension
0.467 0.533 0.000
I31 Other diseases of pericardium
0.465 0.534 0.000
I22.8 Subsequent myocardial infarction of other sites
0.465 0.535 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.462 0.537 0.000
Z82.2 Family history of deafness and hearing loss
0.462 0.537 0.000
Z82.1 Family history of blindness and visual loss
0.462 0.537 0.000
I97.9 Postprocedural disorder of circulatory system, unspecified
0.462 0.538 0.000
I97.2 Postmastectomy lymphoedema syndrome
0.462 0.538 0.000
I97.0 Postcardiotomy syndrome
0.462 0.538 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.461 0.539 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.460 0.540 0.000
M67.8 Other specified disorders of synovium and tendon
0.454 0.546 0.000
Chapter XX External causes of morbidity and mortality
0.451 0.549 0.000
H53-H54 Visual disturbances and blindness
0.450 0.550 0.000
I72.3 Aneurysm of iliac artery
0.450 0.550 0.000
I33.0 Acute and subacute infective endocarditis
0.450 0.550 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.449 0.551 0.000
H25-H28 Disorders of lens
0.449 0.551 0.000
Chapter VIII Diseases of the ear and mastoid process
0.449 0.551 0.000
I49.9 Cardiac arrhythmia, unspecified
0.448 0.552 0.000
I24.8 Other forms of acute ischaemic heart disease
0.447 0.553 0.000
M81 Osteoporosis without pathological fracture
0.443 0.557 0.000
I46.9 Cardiac arrest, unspecified
0.441 0.559 0.000
I07.9 Tricuspid valve disease, unspecified
0.438 0.561 0.000
I07.8 Other tricuspid valve diseases
0.438 0.561 0.000
I07.2 Tricuspid stenosis with insufficiency
0.438 0.561 0.000
I07.0 Tricuspid stenosis
0.438 0.561 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.436 0.564 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.434 0.566 0.000
H54 Blindness and low vision
0.431 0.569 0.000
I72.0 Aneurysm of carotid artery
0.426 0.574 0.000
Y95 Nosocomial condition
0.426 0.574 0.000
H26 Other cataract
0.422 0.578 0.000
M84 Disorders of continuity of bone
0.422 0.578 0.000
I30.8 Other forms of acute pericarditis
0.421 0.579 0.000
I30.1 Infective pericarditis
0.421 0.579 0.000
I30.0 Acute nonspecific idiopathic pericarditis
0.421 0.579 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.416 0.584 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.415 0.585 0.000
H10-H13 Disorders of conjunctiva
0.411 0.589 0.000
H40-H42 Glaucoma
0.410 0.590 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.410 0.590 0.000
H26.4 After-cataract
0.409 0.591 0.000
H54.4 Blindness, one eye
0.408 0.592 0.000
V20-V29 Motorcycle rider injured in transport accident
0.407 0.592 0.000
I20 Angina pectoris
0.405 0.595 0.000
H60-H62 Diseases of external ear
0.402 0.598 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.400 0.600 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.399 0.600 0.000
I71 Aortic aneurysm and dissection
0.399 0.601 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.398 0.602 0.000
M81.4 Drug-induced osteoporosis
0.396 0.603 0.000
I35.8 Other aortic valve disorders
0.396 0.604 0.001
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.396 0.604 0.000
M91-M94 Chondropathies
0.396 0.604 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.395 0.605 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.390 0.610 0.000
M66 Spontaneous rupture of synovium and tendon
0.389 0.611 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.388 0.612 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.385 0.615 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.384 0.616 0.000
I70.01 Atherosclerosis of aorta (with gangrene)
0.381 0.619 0.000
I70.00 Atherosclerosis of aorta (without gangrene)
0.381 0.619 0.000
I70.11 Atherosclerosis of renal artery (with gangrene)
0.381 0.619 0.000
I70.10 Atherosclerosis of renal artery (without gangrene)
0.381 0.619 0.000
I70.81 Atherosclerosis of other arteries (with gangrene)
0.381 0.619 0.000
I70.80 Atherosclerosis of other arteries (without gangrene)
0.381 0.619 0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.381 0.619 0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.381 0.619 0.000
H90-H95 Other disorders of ear
0.381 0.619 0.000
H61 Other disorders of external ear
0.380 0.620 0.000
I78.9 Disease of capillaries, unspecified
0.378 0.622 0.000
I78.8 Other diseases of capillaries
0.378 0.622 0.000
M50-M54 Other dorsopathies
0.376 0.624 0.000
M81.9 Osteoporosis, unspecified
0.376 0.624 0.000
I95.2 Hypotension due to drugs
0.372 0.628 0.000
M67.1 Other contracture of tendon (sheath)
0.372 0.628 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.371 0.629 0.000
M85 Other disorders of bone density and structure
0.371 0.629 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.371 0.629 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.369 0.631 0.000
H27 Other disorders of lens
0.369 0.631 0.000
H40 Glaucoma
0.369 0.631 0.000
I01.9 Acute rheumatic heart disease, unspecified
0.368 0.632 0.000
I01.8 Other acute rheumatic heart disease
0.368 0.632 0.000
I01.2 Acute rheumatic myocarditis
0.368 0.632 0.000
I01.1 Acute rheumatic endocarditis
0.368 0.632 0.000
I01.0 Acute rheumatic pericarditis
0.368 0.632 0.000
I02.9 Rheumatic chorea without heart involvement
0.368 0.632 0.000
I02.0 Rheumatic chorea with heart involvement
0.368 0.632 0.000
H53 Visual disturbances
0.368 0.632 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.367 0.633 0.000
L50-L54 Urticaria and erythema
0.367 0.633 0.000
M65.1 Other infective (teno)synovitis
0.366 0.634 0.000
H50 Other strabismus
0.365 0.635 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.365 0.635 0.000
M80 Osteoporosis with pathological fracture
0.364 0.636 0.000
H11 Other disorders of conjunctiva
0.364 0.636 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.364 0.636 0.000
Y60.0 During surgical operation
0.360 0.640 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.358 0.642 0.000
I07.1 Tricuspid insufficiency
0.356 0.644 0.000
M65.8 Other synovitis and tenosynovitis
0.356 0.644 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.356 0.644 0.000
I20.9 Angina pectoris, unspecified
0.355 0.645 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.355 0.645 0.000
H26.8 Other specified cataract
0.355 0.645 0.000
I34 Nonrheumatic mitral valve disorders
0.354 0.646 0.000
M81.40 Drug-induced osteoporosis (Multiple sites)
0.352 0.648 0.000
H54.7 Unspecified visual loss
0.352 0.648 0.000
M40-M43 Deforming dorsopathies
0.352 0.648 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.351 0.649 0.000
H61.0 Perichondritis of external ear
0.351 0.649 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.350 0.650 0.000
H40.2 Primary angle-closure glaucoma
0.350 0.650 0.000
M45-M49 Spondylopathies
0.349 0.651 0.000
H25 Senile cataract
0.349 0.651 0.000
M60-M63 Disorders of muscles
0.347 0.653 0.000
W50-W64 Exposure to animate mechanical forces
0.347 0.653 0.000
M70-M79 Other soft tissue disorders
0.346 0.654 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.345 0.655 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.345 0.655 0.000
X20-X29 Contact with venomous animals and plants
0.344 0.656 0.000
M65.2 Calcific tendinitis
0.344 0.656 0.000
M65.0 Abscess of tendon sheath
0.344 0.656 0.000
M67.9 Disorder of synovium and tendon, unspecified
0.343 0.656 0.000
M67.4 Ganglion
0.343 0.656 0.000
M67.3 Transient synovitis
0.343 0.656 0.000
M67.0 Short Achilles tendon (acquired)
0.343 0.656 0.000
M86-M90 Other osteopathies
0.342 0.658 0.000
M83 Adult osteomalacia
0.342 0.658 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.342 0.658 0.000
W20-W49 Exposure to inanimate mechanical forces
0.341 0.659 0.000
M50 Cervical disk disorders
0.340 0.660 0.000
H65-H75 Diseases of middle ear and mastoid
0.340 0.660 0.000
M82 Osteoporosis in diseases classified elsewhere
0.339 0.661 0.000
L53 Other erythematous conditions
0.339 0.661 0.000
V23.4 Driver injured in traffic accident
0.338 0.662 0.000
H54.0 Blindness, both eyes
0.338 0.662 0.000
M92 Other juvenile osteochondrosis
0.337 0.663 0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.336 0.664 0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.336 0.664 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.336 0.664 0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.336 0.664 0.000
H61.2 Impacted cerumen
0.334 0.666 0.000
M84.0 Malunion of fracture
0.334 0.666 0.000
I31.8 Other specified diseases of pericardium
0.334 0.666 0.000
I31.2 Haemopericardium, not elsewhere classified
0.334 0.666 0.000
I31.1 Chronic constrictive pericarditis
0.334 0.666 0.000
I31.0 Chronic adhesive pericarditis
0.334 0.666 0.000
X10-X19 Contact with heat and hot substances
0.333 0.667 0.000
H80-H83 Diseases of inner ear
0.333 0.667 0.000
V40-V49 Car occupant injured in transport accident
0.332 0.668 0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.330 0.669 0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.330 0.669 0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.330 0.669 0.000
I98.0 Cardiovascular syphilis
0.330 0.669 0.000
M00-M03 Infectious arthropathies
0.329 0.670 0.000
H50.0 Convergent concomitant strabismus
0.329 0.671 0.000
H53.1 Subjective visual disturbances
0.327 0.673 0.000
H90 Conductive and sensorineural hearing loss
0.327 0.673 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.326 0.674 0.000
H25.8 Other senile cataract
0.325 0.675 0.000
Y35-Y36 Legal intervention and operations of war
0.324 0.676 0.000
Y10-Y34 Event of undetermined intent
0.324 0.676 0.000
X85-X99 Assault
0.324 0.676 0.000
X30-X39 Exposure to forces of nature
0.324 0.676 0.000
X00-X09 Exposure to smoke, fire and flames
0.324 0.676 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.324 0.676 0.000
W75-W84 Other accidental threats to breathing
0.324 0.676 0.000
W65-W74 Accidental drowning and submersion
0.324 0.676 0.000
V98-V99 Other and unspecified transport accidents
0.324 0.676 0.000
V95-V97 Air and space transport accidents
0.324 0.676 0.000
V90-V94 Water transport accidents
0.324 0.676 0.000
V70-V79 Bus occupant injured in transport accident
0.324 0.676 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.324 0.676 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.324 0.676 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.324 0.676 0.000
V01-V09 Pedestrian injured in transport accident
0.324 0.676 0.000
L84 Corns and callosities
0.324 0.676 0.000
L91 Hypertrophic disorders of skin
0.323 0.677 0.000
Y00-Y09 Assault
0.323 0.677 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.322 0.678 0.000
X50-X57 Overexertion, travel and privation
0.320 0.680 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.319 0.680 0.000
H50.9 Strabismus, unspecified
0.319 0.681 0.000
V27 Motorcycle rider injured in collision with fixed or stationary object
0.319 0.681 0.000
H26.2 Complicated cataract
0.319 0.681 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.318 0.682 0.000
M50.1 Cervical disk disorder with radiculopathy
0.318 0.682 0.000
M81.8 Other osteoporosis
0.317 0.682 0.000
M81.6 Localised osteoporosis [Lequesne]
0.317 0.682 0.000
M81.5 Idiopathic osteoporosis
0.317 0.682 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.317 0.682 0.000
M81.2 Osteoporosis of disuse
0.317 0.682 0.000
M81.1 Postoophorectomy osteoporosis
0.317 0.682 0.000
M81.0 Postmenopausal osteoporosis
0.317 0.682 0.000
L50 Urticaria
0.317 0.683 0.000
H53.4 Visual field defects
0.317 0.683 0.000
I50 Heart failure
0.316 0.683 0.000
M66.0 Rupture of popliteal cyst
0.314 0.686 0.000
H26.1 Traumatic cataract
0.313 0.687 0.000
M81.49 Drug-induced osteoporosis (Site unspecified)
0.312 0.688 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.312 0.688 0.000
H11.9 Disorder of conjunctiva, unspecified
0.312 0.688 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.311 0.688 0.000
Y98 Lifestyle-related condition
0.311 0.688 0.000
Y97 Environmental-pollution-related condition
0.311 0.688 0.000
Y96 Work-related condition
0.311 0.688 0.000
L53.9 Erythematous condition, unspecified
0.311 0.689 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.310 0.690 0.000
H10 Conjunctivitis
0.310 0.690 0.000
Y60.4 During endoscopic examination
0.310 0.690 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.310 0.690 0.000
H54.6 Unqualified visual loss, one eye
0.309 0.691 0.000
H54.5 Low vision, one eye
0.309 0.691 0.000
H54.3 Unqualified visual loss, both eyes
0.309 0.691 0.000
H54.2 Low vision, both eyes
0.309 0.691 0.000
H54.1 Blindness, one eye, low vision, other eye
0.309 0.691 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.309 0.691 0.000
H65 Nonsuppurative otitis media
0.309 0.691 0.000
X45 Accidental poisoning by and exposure to alcohol
0.309 0.691 0.000
V10-V19 Pedal cyclist injured in transport accident
0.308 0.692 0.000
Y65 Other misadventures during surgical and medical care
0.307 0.693 0.000
Chapter V Mental and behavioural disorders
0.307 0.693 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.307 0.693 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.306 0.694 0.000
H93 Other disorders of ear, not elsewhere classified
0.304 0.696 0.000
M45 Ankylosing spondylitis
0.303 0.697 0.000
H26.0 Infantile, juvenile and presenile cataract
0.303 0.697 0.000
H26.3 Drug-induced cataract
0.303 0.697 0.000
H27.0 Aphakia
0.303 0.697 0.000
M84.9 Disorder of continuity of bone, unspecified
0.303 0.697 0.000
M84.8 Other disorders of continuity of bone
0.303 0.697 0.000
M84.3 Stress fracture, not elsewhere classified
0.303 0.697 0.000
M84.2 Delayed union of fracture
0.303 0.697 0.000
I30.9 Acute pericarditis, unspecified
0.302 0.698 0.001
M84.4 Pathological fracture, not elsewhere classified
0.302 0.698 0.000
V80-V89 Other land transport accidents
0.301 0.699 0.000
H40.0 Glaucoma suspect
0.301 0.699 0.000
M65.3 Trigger finger
0.301 0.699 0.000
I10-I15 Hypertensive diseases
0.299 0.700 0.000
M50.3 Other cervical disk degeneration
0.299 0.701 0.000
I73 Other peripheral vascular diseases
0.298 0.702 0.000
Y64 Contaminated medical or biological substances
0.298 0.702 0.000
Y63 Failure in dosage during surgical and medical care
0.298 0.702 0.000
Y62 Failure of sterile precautions during surgical and medical care
0.298 0.702 0.000
Y61 Foreign object accidentally left in body during surgical and medical care
0.298 0.702 0.000
Y69 Unspecified misadventure during surgical and medical care
0.298 0.702 0.000
Y66 Nonadministration of surgical and medical care
0.298 0.702 0.000
L91.0 Keloid scar
0.297 0.703 0.000
H92 Otalgia and effusion of ear
0.296 0.704 0.000
M92.6 Juvenile osteochondrosis of tarsus
0.295 0.705 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.295 0.705 0.000
L94 Other localised connective tissue disorders
0.294 0.706 0.000
H42 Glaucoma in diseases classified elsewhere
0.294 0.706 0.000
M99 Biomechanical lesions, not elsewhere classified
0.294 0.706 0.000
H53.0 Amblyopia ex anopsia
0.293 0.707 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.293 0.707 0.000
H50.4 Other and unspecified heterotropia
0.293 0.707 0.000
V29 Motorcycle rider injured in other and unspecified transport accidents
0.292 0.708 0.000
V28 Motorcycle rider injured in noncollision transport accident
0.292 0.708 0.000
V26 Motorcycle rider injured in collision with other nonmotor vehicle
0.292 0.708 0.000
V25 Motorcycle rider injured in collision with railway train or railway vehicle
0.292 0.708 0.000
V24 Motorcycle rider injured in collision with heavy transport vehicle or bus
0.292 0.708 0.000
V22 Motorcycle rider injured in collision with two- or three-wheeled motor vehicle
0.292 0.708 0.000
V21 Motorcycle rider injured in collision with pedal cycle
0.292 0.708 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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