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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117082835
log Bayes Factor = 20.3366
Chromosome 22   position 27,493,062  (GRCh37) Explore rs117082835 on Ensembl!
Variant rs117082835 is part of Cluster X0189

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
0.999 0.001 0.000
M06 Other rheumatoid arthritis
0.999 0.001 0.000
M06.9 Rheumatoid arthritis, unspecified
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.998 0.002 0.000
Chapter IX Diseases of the circulatory system
0.997 0.003 0.000
B95-B98 Bacterial, viral and other infectious agents
0.996 0.004 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.993 0.007 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.993 0.007 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.990 0.010 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.988 0.012 0.000
Z50 Care involving use of rehabilitation procedures
0.983 0.017 0.000
J09-J18 Influenza and pneumonia
0.980 0.020 0.000
M20-M25 Other joint disorders
0.978 0.022 0.000
I30-I52 Other forms of heart disease
0.975 0.025 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.972 0.028 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.970 0.030 0.000
Chapter XX External causes of morbidity and mortality
0.968 0.032 0.000
J18 Pneumonia, organism unspecified
0.968 0.032 0.000
Chapter VII Diseases of the eye and adnexa
0.966 0.034 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.965 0.035 0.000
M25 Other joint disorders, not elsewhere classified
0.962 0.038 0.000
Z50.1 Other physical therapy
0.956 0.044 0.000
I44 Atrioventricular and left bundle-branch block
0.954 0.046 0.000
J18.9 Pneumonia, unspecified
0.953 0.047 0.000
Chapter II Neoplasms
0.953 0.047 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.952 0.048 0.000
Chapter XIV Diseases of the genitourinary system
0.949 0.051 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.948 0.052 0.000
I05-I09 Chronic rheumatic heart diseases
0.943 0.057 0.000
Chapter VI Diseases of the nervous system
0.941 0.059 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.938 0.062 0.000
J90-J94 Other diseases of pleura
0.937 0.063 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.927 0.073 0.000
Z90.7 Acquired absence of genital organ(s)
0.918 0.082 0.000
A30-A49 Other bacterial diseases
0.918 0.082 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.917 0.083 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.917 0.083 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.916 0.084 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.914 0.086 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.914 0.086 0.000
M25.7 Osteophyte
0.912 0.088 0.000
I08 Multiple valve diseases
0.909 0.091 0.000
L60-L75 Disorders of skin appendages
0.908 0.092 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.905 0.095 0.000
I50 Heart failure
0.905 0.095 0.000
J30-J39 Other diseases of upper respiratory tract
0.902 0.098 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.900 0.100 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.900 0.100 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.897 0.102 0.000
W00-W19 Falls
0.896 0.104 0.000
B35-B49 Mycoses
0.895 0.105 0.000
Z85 Personal history of malignant neoplasm
0.894 0.106 0.000
N30-N39 Other diseases of urinary system
0.892 0.108 0.000
I44.7 Left bundle-branch block, unspecified
0.887 0.113 0.000
J90 Pleural effusion, not elsewhere classified
0.887 0.113 0.000
Chapter VIII Diseases of the ear and mastoid process
0.887 0.113 0.000
I60-I69 Cerebrovascular diseases
0.887 0.113 0.000
J34 Other disorders of nose and nasal sinuses
0.885 0.115 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.874 0.126 0.000
C64-C68 Malignant neoplasms of urinary tract
0.873 0.127 0.000
H40-H42 Glaucoma
0.873 0.127 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.872 0.128 0.000
S40-S49 Injuries to the shoulder and upper arm
0.871 0.129 0.000
T81 Complications of procedures, not elsewhere classified
0.871 0.129 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.869 0.131 0.000
Z42 Follow-up care involving plastic surgery
0.867 0.133 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.864 0.136 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.863 0.137 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.860 0.140 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.858 0.142 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.854 0.146 0.000
N39 Other disorders of urinary system
0.847 0.153 0.000
O60-O75 Complications of labour and delivery
0.846 0.154 0.000
Z96 Presence of other functional implants
0.845 0.155 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.845 0.155 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.843 0.157 0.000
S70-S79 Injuries to the hip and thigh
0.842 0.158 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.839 0.161 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.839 0.161 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.838 0.162 0.000
W19 Unspecified fall
0.838 0.162 0.000
J34.2 Deviated nasal septum
0.837 0.163 0.000
I63 Cerebral infarction
0.837 0.163 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.835 0.165 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.834 0.166 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.833 0.167 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.833 0.167 0.000
A00-A09 Intestinal infectious diseases
0.833 0.167 0.000
M31 Other necrotising vasculopathies
0.833 0.167 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.832 0.168 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.831 0.169 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.831 0.169 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.830 0.170 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.829 0.170 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.829 0.171 0.000
N92 Excessive, frequent and irregular menstruation
0.828 0.172 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.827 0.173 0.000
M25.5 Pain in joint
0.826 0.174 0.000
G90-G99 Other disorders of the nervous system
0.823 0.177 0.000
I50.0 Congestive heart failure
0.821 0.179 0.000
Z83 Family history of other specific disorders
0.820 0.180 0.000
B37 Candidiasis
0.819 0.181 0.000
N39.0 Urinary tract infection, site not specified
0.818 0.182 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.816 0.184 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.815 0.185 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.815 0.185 0.000
A41 Other septicaemia
0.815 0.185 0.000
M10 Gout
0.814 0.186 0.000
I44.0 Atrioventricular block, first degree
0.813 0.187 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.812 0.188 0.000
Z99.1 Dependence on respirator
0.812 0.188 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.809 0.191 0.000
Z89 Acquired absence of limb
0.809 0.191 0.000
M80-M85 Disorders of bone density and structure
0.809 0.191 0.000
H40 Glaucoma
0.807 0.193 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.807 0.193 0.000
I44.2 Atrioventricular block, complete
0.806 0.194 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.806 0.194 0.000
M25.8 Other specified joint disorders
0.805 0.195 0.000
Z99.3 Dependence on wheelchair
0.804 0.196 0.000
Z46 Fitting and adjustment of other devices
0.801 0.199 0.000
I63.9 Cerebral infarction, unspecified
0.801 0.199 0.000
M35 Other systemic involvement of connective tissue
0.801 0.199 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.801 0.199 0.000
Z50.2 Alcohol rehabilitation
0.800 0.200 0.000
M05 Seropositive rheumatoid arthritis
0.800 0.200 0.000
M25.76 Osteophyte (Lower leg)
0.799 0.201 0.000
Z96.0 Presence of urogenital implants
0.799 0.201 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.798 0.201 0.000
Z45 Adjustment and management of implanted device
0.797 0.203 0.000
Y43 Primarily systemic agents
0.796 0.204 0.000
M70-M79 Other soft tissue disorders
0.796 0.204 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.796 0.204 0.000
H30-H36 Disorders of choroid and retina
0.795 0.205 0.000
Chapter XXII Codes for special purposes
0.793 0.207 0.000
L20-L30 Dermatitis and eczema
0.792 0.208 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.792 0.208 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.790 0.210 0.000
C67 Malignant neoplasm of bladder
0.789 0.211 0.000
C83.3 Large cell (diffuse)
0.786 0.214 0.000
Z41 Procedures for purposes other than remedying health state
0.785 0.215 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.785 0.215 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.782 0.218 0.000
N92.6 Irregular menstruation, unspecified
0.782 0.218 0.000
M25.78 Osteophyte (Other)
0.780 0.220 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.780 0.220 0.000
H53-H54 Visual disturbances and blindness
0.779 0.221 0.000
G20-G26 Extrapyramidal and movement disorders
0.779 0.221 0.000
S42 Fracture of shoulder and upper arm
0.778 0.222 0.000
Z80 Family history of malignant neoplasm
0.777 0.223 0.000
S50-S59 Injuries to the elbow and forearm
0.777 0.223 0.000
I46 Cardiac arrest
0.777 0.223 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.777 0.223 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.775 0.225 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.775 0.225 0.000
M06.0 Seronegative rheumatoid arthritis
0.774 0.226 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.774 0.226 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.773 0.227 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.772 0.227 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.771 0.229 0.000
J35 Chronic diseases of tonsils and adenoids
0.771 0.229 0.000
I73 Other peripheral vascular diseases
0.771 0.229 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.771 0.229 0.000
A49 Bacterial infection of unspecified site
0.770 0.230 0.000
N00-N08 Glomerular diseases
0.769 0.231 0.000
Z34 Supervision of normal pregnancy
0.769 0.231 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.769 0.231 0.000
E10-E14 Diabetes mellitus
0.768 0.232 0.000
I50.9 Heart failure, unspecified
0.765 0.235 0.000
J18.0 Bronchopneumonia, unspecified
0.764 0.236 0.000
L40-L45 Papulosquamous disorders
0.763 0.237 0.000
M25.74 Osteophyte (Hand)
0.763 0.237 0.000
C91 Lymphoid leukaemia
0.761 0.239 0.000
A04 Other bacterial intestinal infections
0.760 0.239 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.760 0.240 0.000
I08.0 Disorders of both mitral and aortic valves
0.759 0.241 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.758 0.242 0.000
B37.0 Candidal stomatitis
0.758 0.242 0.000
Z37 Outcome of delivery
0.757 0.243 0.000
Chapter V Mental and behavioural disorders
0.757 0.243 0.000
Z82.3 Family history of stroke
0.757 0.243 0.000
H50 Other strabismus
0.756 0.244 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.755 0.245 0.000
S90-S99 Injuries to the ankle and foot
0.755 0.245 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.755 0.245 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.753 0.247 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.753 0.247 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.752 0.248 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.751 0.249 0.000
M00-M03 Infectious arthropathies
0.750 0.250 0.000
L71 Rosacea
0.750 0.250 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.750 0.250 0.000
T86 Failure and rejection of transplanted organs and tissues
0.750 0.250 0.000
M34 Systemic sclerosis
0.749 0.251 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.746 0.254 0.000
S80-S89 Injuries to the knee and lower leg
0.745 0.255 0.000
L50-L54 Urticaria and erythema
0.745 0.255 0.000
J18.1 Lobar pneumonia, unspecified
0.744 0.256 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.744 0.256 0.000
R47-R49 Symptoms and signs involving speech and voice
0.744 0.256 0.000
Z90.5 Acquired absence of kidney
0.744 0.256 0.000
M86-M90 Other osteopathies
0.743 0.257 0.000
L72.1 Trichilemmal cyst
0.742 0.258 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.742 0.258 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.741 0.259 0.000
N25-N29 Other disorders of kidney and ureter
0.740 0.259 0.000
I33 Acute and subacute endocarditis
0.740 0.260 0.000
M24 Other specific joint derangements
0.740 0.260 0.000
Z33 Pregnant state, incidental
0.740 0.260 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.740 0.260 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.739 0.261 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.739 0.261 0.000
M07 Psoriatic and enteropathic arthropathies
0.739 0.261 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.738 0.262 0.000
O72 Postpartum haemorrhage
0.737 0.263 0.000
H65-H75 Diseases of middle ear and mastoid
0.737 0.263 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.737 0.263 0.000
J60-J70 Lung diseases due to external agents
0.737 0.263 0.000
W20-W49 Exposure to inanimate mechanical forces
0.737 0.263 0.000
I44.1 Atrioventricular block, second degree
0.737 0.263 0.000
C34 Malignant neoplasm of bronchus and lung
0.737 0.263 0.000
X60-X84 Intentional self-harm
0.736 0.264 0.000
Z86 Personal history of certain other diseases
0.735 0.265 0.000
I69 Sequelae of cerebrovascular disease
0.735 0.265 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.734 0.266 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.734 0.266 0.000
T51 Toxic effect of alcohol
0.734 0.266 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.734 0.266 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.733 0.267 0.000
H55-H59 Other disorders of eye and adnexa
0.731 0.268 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.730 0.270 0.000
B15-B19 Viral hepatitis
0.729 0.270 0.000
M31.6 Other giant cell arteritis
0.729 0.271 0.000
C83.0 Small cell (diffuse)
0.728 0.272 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.728 0.272 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.727 0.273 0.000
J00-J06 Acute upper respiratory infections
0.726 0.274 0.000
H40.9 Glaucoma, unspecified
0.725 0.275 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.725 0.275 0.000
Z47 Other orthopaedic follow-up care
0.725 0.275 0.000
Z35 Supervision of high-risk pregnancy
0.725 0.275 0.000
G93 Other disorders of brain
0.724 0.276 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.723 0.276 0.000
H80-H83 Diseases of inner ear
0.723 0.277 0.000
D00-D09 In situ neoplasms
0.723 0.277 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.723 0.277 0.000
L73 Other follicular disorders
0.723 0.277 0.000
G62 Other polyneuropathies
0.722 0.278 0.000
R25 Abnormal involuntary movements
0.722 0.278 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.722 0.278 0.000
C67.9 Bladder, unspecified
0.722 0.278 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.719 0.281 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.719 0.281 0.000
I51 Complications and ill-defined descriptions of heart disease
0.719 0.281 0.000
Z50.8 Care involving use of rehabilitation procedures
0.719 0.281 0.000
W19.2 School, other institution and public administrative area
0.718 0.282 0.000
I74 Arterial embolism and thrombosis
0.718 0.282 0.000
Z99.2 Dependence on renal dialysis
0.718 0.282 0.000
N20-N23 Urolithiasis
0.717 0.283 0.000
H35 Other retinal disorders
0.717 0.283 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.717 0.283 0.000
Y52 Agents primarily affecting the cardiovascular system
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.717 0.283 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B65-B83 Helminthiases
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A80-A89 Viral infections of the central nervous system
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
M14 Arthropathies in other diseases classified elsewhere
0.716 0.283 0.000
M12 Other specific arthropathies
0.716 0.283 0.000
M11 Other crystal arthropathies
0.716 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.716 0.283 0.000
M08 Juvenile arthritis
0.716 0.283 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.716 0.284 0.000
M06.8 Other specified rheumatoid arthritis
0.716 0.284 0.000
M06.4 Inflammatory polyarthropathy
0.716 0.284 0.000
M06.3 Rheumatoid nodule
0.716 0.284 0.000
M06.2 Rheumatoid bursitis
0.716 0.284 0.000
M06.1 Adult-onset Still's disease
0.716 0.284 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.716 0.284 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.716 0.284 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.716 0.284 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.716 0.284 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.715 0.285 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.715 0.285 0.000
Z95.4 Presence of other heart-valve replacement
0.715 0.285 0.000
I00-I02 Acute rheumatic fever
0.715 0.285 0.000
Z50.5 Speech therapy
0.714 0.285 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.714 0.286 0.000
Z40 Prophylactic surgery
0.714 0.286 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.714 0.286 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.712 0.288 0.000
T87 Complications peculiar to reattachment and amputation
0.712 0.288 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.712 0.288 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.712 0.288 0.000
Z84 Family history of other conditions
0.712 0.288 0.000
Z81 Family history of mental and behavioural disorders
0.712 0.288 0.000
Y43.3 Other antineoplastic drugs
0.712 0.288 0.000
I31 Other diseases of pericardium
0.711 0.288 0.000
N32 Other disorders of bladder
0.711 0.289 0.000
Z54 Convalescence
0.710 0.290 0.000
Z52 Donors of organs and tissues
0.710 0.290 0.000
Z49 Care involving dialysis
0.710 0.290 0.000
Z44 Fitting and adjustment of external prosthetic device
0.710 0.290 0.000
S60-S69 Injuries to the wrist and hand
0.710 0.290 0.000
W19.9 Unspecified place
0.710 0.290 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.707 0.293 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.707 0.293 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.706 0.294 0.000
C50-C50 Malignant neoplasm of breast
0.705 0.295 0.000
Z50.6 Orthoptic training
0.705 0.295 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.705 0.295 0.000
Z50.3 Drug rehabilitation
0.705 0.295 0.000
J94 Other pleural conditions
0.705 0.295 0.000
Y40 Systemic antibiotics
0.704 0.296 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.703 0.296 0.000
M25.51 Pain in joint (Shoulder region)
0.704 0.296 0.000
J17 Pneumonia in diseases classified elsewhere
0.703 0.297 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.703 0.297 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.703 0.297 0.000
J12 Viral pneumonia, not elsewhere classified
0.703 0.297 0.000
J11 Influenza, virus not identified
0.703 0.297 0.000
J10 Influenza due to identified influenza virus
0.703 0.297 0.000
J14 Pneumonia due to Haemophilus influenzae
0.703 0.297 0.000
J09 Influenza due to certain identified influenza virus
0.703 0.297 0.000
M22 Disorders of patella
0.702 0.298 0.000
N10-N16 Renal tubulo-interstitial diseases
0.701 0.299 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.701 0.299 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.701 0.299 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.701 0.299 0.000
M33 Dermatopolymyositis
0.701 0.299 0.000
M32 Systemic lupus erythematosus
0.701 0.299 0.000
M30 Polyarteritis nodosa and related conditions
0.701 0.299 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.700 0.300 0.000
M21 Other acquired deformities of limbs
0.699 0.301 0.000
R29.6 Tendency to fall, not elsewhere classified
0.699 0.301 0.000
I52 Other heart disorders in diseases classified elsewhere
0.699 0.301 0.000
I48 Atrial fibrillation and flutter
0.699 0.301 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.699 0.301 0.000
I41 Myocarditis in diseases classified elsewhere
0.699 0.301 0.000
I40 Acute myocarditis
0.699 0.301 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.699 0.301 0.000
I37 Pulmonary valve disorders
0.699 0.301 0.000
I36 Nonrheumatic tricuspid valve disorders
0.699 0.301 0.000
I32 Pericarditis in diseases classified elsewhere
0.699 0.301 0.000
I30 Acute pericarditis
0.699 0.301 0.000
G70-G73 Diseases of myoneural junction and muscle
0.699 0.301 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.698 0.302 0.000
O48 Prolonged pregnancy
0.698 0.302 0.000
M35.3 Polymyalgia rheumatica
0.698 0.302 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.698 0.302 0.000
J80 Adult respiratory distress syndrome
0.698 0.302 0.000
T43.2 Other and unspecified antidepressants
0.698 0.302 0.000
L10-L14 Bullous disorders
0.697 0.303 0.000
T82.1 Mechanical complication of cardiac electronic device
0.697 0.303 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.697 0.303 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.696 0.304 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.696 0.304 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.696 0.304 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.696 0.304 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.696 0.304 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.696 0.304 0.000
I73.9 Peripheral vascular disease, unspecified
0.696 0.304 0.000
Z85.6 Personal history of leukaemia
0.695 0.305 0.000
E11 Non-insulin-dependent diabetes mellitus
0.695 0.305 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.694 0.306 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.694 0.306 0.000
Y35-Y36 Legal intervention and operations of war
0.694 0.306 0.000
Y10-Y34 Event of undetermined intent
0.694 0.306 0.000
Y00-Y09 Assault
0.694 0.306 0.000
X85-X99 Assault
0.694 0.306 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.694 0.306 0.000
X50-X57 Overexertion, travel and privation
0.694 0.306 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.694 0.306 0.000
X30-X39 Exposure to forces of nature
0.694 0.306 0.000
X20-X29 Contact with venomous animals and plants
0.694 0.306 0.000
X10-X19 Contact with heat and hot substances
0.694 0.306 0.000
X00-X09 Exposure to smoke, fire and flames
0.694 0.306 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.694 0.306 0.000
W75-W84 Other accidental threats to breathing
0.694 0.306 0.000
W65-W74 Accidental drowning and submersion
0.694 0.306 0.000
W50-W64 Exposure to animate mechanical forces
0.694 0.306 0.000
V98-V99 Other and unspecified transport accidents
0.694 0.306 0.000
V95-V97 Air and space transport accidents
0.694 0.306 0.000
V90-V94 Water transport accidents
0.694 0.306 0.000
V80-V89 Other land transport accidents
0.694 0.306 0.000
V70-V79 Bus occupant injured in transport accident
0.694 0.306 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.694 0.306 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.694 0.306 0.000
V40-V49 Car occupant injured in transport accident
0.694 0.306 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.694 0.306 0.000
V20-V29 Motorcycle rider injured in transport accident
0.694 0.306 0.000
V01-V09 Pedestrian injured in transport accident
0.694 0.306 0.000
J18.8 Other pneumonia, organism unspecified
0.694 0.306 0.000
J18.2 Hypostatic pneumonia, unspecified
0.694 0.306 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.694 0.306 0.000
Y44 Agents primarily affecting blood constituents
0.693 0.307 0.000
M25.84 Other specified joint disorders (Hand)
0.693 0.307 0.000
O80-O84 Delivery
0.692 0.307 0.000
I35 Nonrheumatic aortic valve disorders
0.692 0.308 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.692 0.308 0.000
H10-H13 Disorders of conjunctiva
0.692 0.308 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.692 0.308 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.692 0.308 0.000
M50-M54 Other dorsopathies
0.692 0.308 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.691 0.309 0.000
M25.9 Joint disorder, unspecified
0.690 0.310 0.000
M25.3 Other instability of joint
0.690 0.310 0.000
M25.2 Flail joint
0.690 0.310 0.000
M25.1 Fistula of joint
0.690 0.310 0.000
M25.0 Haemarthrosis
0.690 0.310 0.000
N93 Other abnormal uterine and vaginal bleeding
0.690 0.310 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.689 0.311 0.000
N92.3 Ovulation bleeding
0.689 0.311 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.689 0.311 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.688 0.312 0.000
Z45.2 Adjustment and management of vascular access device
0.687 0.313 0.000
J93 Pneumothorax
0.687 0.313 0.000
J91 Pleural effusion in conditions classified elsewhere
0.686 0.314 0.000
I72 Other aneurysm
0.686 0.314 0.000
Z97 Presence of other devices
0.686 0.314 0.000
W19.4 Street and highway
0.686 0.314 0.000
I44.6 Other and unspecified fascicular block
0.684 0.316 0.000
I44.5 Left posterior fascicular block
0.684 0.316 0.000
I44.4 Left anterior fascicular block
0.684 0.316 0.000
I44.3 Other and unspecified atrioventricular block
0.684 0.316 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.683 0.317 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.683 0.317 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.683 0.317 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.683 0.317 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.683 0.317 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.682 0.318 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.682 0.318 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.682 0.318 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.682 0.318 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.682 0.318 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.682 0.318 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.682 0.318 0.000
T36 Poisoning by systemic antibiotics
0.682 0.318 0.000
M25.53 Pain in joint (Forearm)
0.682 0.318 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.682 0.318 0.000
M10.9 Gout, unspecified
0.681 0.319 0.000
O42 Premature rupture of membranes
0.681 0.319 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.681 0.319 0.000
S70 Superficial injury of hip and thigh
0.679 0.320 0.000
Z90.0 Acquired absence of part of head and neck
0.679 0.321 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.679 0.321 0.000
Z95.0 Presence of cardiac pacemaker
0.679 0.321 0.000
Z90.8 Acquired absence of other organs
0.679 0.321 0.000
H40.2 Primary angle-closure glaucoma
0.679 0.321 0.000
E20-E35 Disorders of other endocrine glands
0.678 0.321 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.678 0.322 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.678 0.322 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.677 0.322 0.000
J35.0 Chronic tonsillitis
0.677 0.323 0.000
M40-M43 Deforming dorsopathies
0.676 0.324 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.676 0.324 0.000
I09 Other rheumatic heart diseases
0.676 0.324 0.000
I06 Rheumatic aortic valve diseases
0.676 0.324 0.000
I05 Rheumatic mitral valve diseases
0.676 0.324 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.676 0.324 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.676 0.324 0.000
T66-T78 Other and unspecified effects of external causes
0.675 0.325 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.675 0.325 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.675 0.325 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.675 0.325 0.000
J39 Other diseases of upper respiratory tract
0.674 0.326 0.000
N85.2 Hypertrophy of uterus
0.674 0.326 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.674 0.326 0.000
N85.0 Endometrial glandular hyperplasia
0.673 0.327 0.000
H52 Disorders of refraction and accommodation
0.672 0.328 0.000
D41.4 Bladder
0.672 0.328 0.000
J20-J22 Other acute lower respiratory infections
0.670 0.330 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.670 0.330 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.668 0.331 0.000
I70 Atherosclerosis
0.668 0.332 0.000
B37.9 Candidiasis, unspecified
0.668 0.332 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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