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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116847944
log Bayes Factor = 14.8527
Chromosome 17   position 32,238,030  (GRCh37) Explore rs116847944 on Ensembl!
Variant rs116847944 is part of Cluster X0072

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
I60-I69 Cerebrovascular diseases
0.999 0.001 0.000
G40-G47 Episodic and paroxysmal disorders
0.999 0.001 0.000
G40 Epilepsy
0.998 0.002 0.000
I69 Sequelae of cerebrovascular disease
0.998 0.002 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.996 0.004 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.996 0.004 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.988 0.012 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.987 0.013 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.987 0.013 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.985 0.015 0.000
Chapter II Neoplasms
0.984 0.016 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.984 0.016 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.981 0.019 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.978 0.022 0.000
G81 Hemiplegia
0.977 0.023 0.000
Chapter X Diseases of the respiratory system
0.970 0.030 0.000
G81.9 Hemiplegia, unspecified
0.969 0.031 0.000
F30-F39 Mood [affective] disorders
0.969 0.031 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.967 0.033 0.000
D70 Agranulocytosis
0.954 0.046 0.000
G40.9 Epilepsy, unspecified
0.954 0.046 0.000
I69.3 Sequelae of cerebral infarction
0.953 0.047 0.000
G90-G99 Other disorders of the nervous system
0.952 0.048 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.950 0.050 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.947 0.053 0.000
I84 Haemorrhoids
0.945 0.055 0.000
I05-I09 Chronic rheumatic heart diseases
0.942 0.058 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.936 0.064 0.000
F10.3 Withdrawal state
0.935 0.065 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.932 0.068 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.932 0.068 0.000
I80 Phlebitis and thrombophlebitis
0.931 0.069 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.918 0.082 0.000
C64-C68 Malignant neoplasms of urinary tract
0.917 0.083 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.916 0.084 0.000
F32 Depressive episode
0.914 0.086 0.000
I08 Multiple valve diseases
0.908 0.092 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.899 0.101 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.897 0.103 0.000
I84.2 Internal haemorrhoids without complication
0.893 0.107 0.000
I84.6 Residual haemorrhoidal skin tags
0.893 0.107 0.000
F33 Recurrent depressive disorder
0.891 0.109 0.000
C34 Malignant neoplasm of bronchus and lung
0.890 0.110 0.000
J40-J47 Chronic lower respiratory diseases
0.890 0.110 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.887 0.113 0.000
Chapter VIII Diseases of the ear and mastoid process
0.886 0.114 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.881 0.119 0.000
F10.1 Harmful use
0.876 0.124 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.875 0.125 0.000
C15-C26 Malignant neoplasms of digestive organs
0.875 0.125 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.871 0.129 0.000
F60-F69 Disorders of adult personality and behaviour
0.867 0.133 0.000
J44 Other chronic obstructive pulmonary disease
0.866 0.134 0.000
D68 Other coagulation defects
0.865 0.135 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.865 0.135 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.862 0.138 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.861 0.139 0.000
D75 Other diseases of blood and blood-forming organs
0.857 0.143 0.000
T40.2 Other opioids
0.852 0.148 0.000
I77 Other disorders of arteries and arterioles
0.852 0.148 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.851 0.149 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.850 0.150 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.849 0.151 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.848 0.152 0.000
G30-G32 Other degenerative diseases of the nervous system
0.848 0.152 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.846 0.154 0.000
G20-G26 Extrapyramidal and movement disorders
0.843 0.157 0.000
F10.2 Dependence syndrome
0.841 0.159 0.000
I63 Cerebral infarction
0.839 0.161 0.000
G93 Other disorders of brain
0.834 0.166 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.833 0.167 0.000
D69 Purpura and other haemorrhagic conditions
0.833 0.167 0.000
C34.9 Bronchus or lung, unspecified
0.833 0.167 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.832 0.168 0.000
C67 Malignant neoplasm of bladder
0.832 0.168 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.831 0.169 0.000
S40-S49 Injuries to the shoulder and upper arm
0.830 0.170 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.830 0.170 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.825 0.174 0.000
J95-J99 Other diseases of the respiratory system
0.825 0.175 0.000
F10.0 Acute intoxication
0.825 0.175 0.000
G91 Hydrocephalus
0.825 0.175 0.000
I84.5 External haemorrhoids without complication
0.823 0.177 0.000
J00-J06 Acute upper respiratory infections
0.822 0.178 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.817 0.183 0.000
J60-J70 Lung diseases due to external agents
0.816 0.184 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.814 0.186 0.000
G40.8 Other epilepsy
0.813 0.187 0.000
T66-T78 Other and unspecified effects of external causes
0.813 0.187 0.000
S90-S99 Injuries to the ankle and foot
0.813 0.187 0.000
F32.9 Depressive episode, unspecified
0.812 0.188 0.000
I74 Arterial embolism and thrombosis
0.809 0.191 0.000
F32.0 Mild depressive episode
0.808 0.192 0.000
S60-S69 Injuries to the wrist and hand
0.807 0.193 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.806 0.194 0.000
Chapter XXII Codes for special purposes
0.805 0.195 0.000
I26 Pulmonary embolism
0.804 0.196 0.000
J43 Emphysema
0.803 0.197 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.798 0.202 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.796 0.204 0.000
I77.8 Other specified disorders of arteries and arterioles
0.790 0.210 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.789 0.211 0.000
C34.1 Upper lobe, bronchus or lung
0.789 0.211 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.789 0.211 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.788 0.212 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.787 0.213 0.000
D72 Other disorders of white blood cells
0.787 0.213 0.000
Chapter VII Diseases of the eye and adnexa
0.786 0.214 0.000
C21 Malignant neoplasm of anus and anal canal
0.785 0.215 0.000
S70-S79 Injuries to the hip and thigh
0.785 0.215 0.000
T86 Failure and rejection of transplanted organs and tissues
0.785 0.215 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.784 0.216 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.783 0.216 0.000
I27 Other pulmonary heart diseases
0.783 0.217 0.000
F33.9 Recurrent depressive disorder, unspecified
0.781 0.219 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.781 0.219 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.781 0.219 0.000
Chapter XX External causes of morbidity and mortality
0.780 0.220 0.000
I67 Other cerebrovascular diseases
0.778 0.222 0.000
F60 Specific personality disorders
0.772 0.228 0.000
I61 Intracerebral haemorrhage
0.772 0.228 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.770 0.230 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.769 0.231 0.000
G25 Other extrapyramidal and movement disorders
0.768 0.232 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.766 0.234 0.000
G41 Status epilepticus
0.766 0.234 0.000
I62 Other nontraumatic intracranial haemorrhage
0.765 0.235 0.000
H90-H95 Other disorders of ear
0.765 0.235 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.762 0.238 0.000
I82 Other venous embolism and thrombosis
0.761 0.239 0.000
I73 Other peripheral vascular diseases
0.760 0.240 0.000
S20-S29 Injuries to the thorax
0.759 0.241 0.000
F00 Dementia in Alzheimer's disease
0.758 0.242 0.000
S10-S19 Injuries to the neck
0.757 0.243 0.000
Chapter XIV Diseases of the genitourinary system
0.757 0.243 0.000
F10.4 Withdrawal state with delirium
0.756 0.244 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.755 0.245 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.755 0.245 0.000
D55-D59 Haemolytic anaemias
0.754 0.246 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.754 0.246 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.753 0.247 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.752 0.248 0.000
G82 Paraplegia and tetraplegia
0.751 0.249 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.751 0.249 0.000
J98 Other respiratory disorders
0.750 0.250 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.748 0.252 0.000
I08.0 Disorders of both mitral and aortic valves
0.748 0.252 0.000
I87 Other disorders of veins
0.747 0.253 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.746 0.254 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.746 0.254 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.744 0.256 0.000
G90 Disorders of autonomic nervous system
0.742 0.258 0.000
T79-T79 Certain early complications of trauma
0.741 0.258 0.000
J43.9 Emphysema, unspecified
0.740 0.260 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.740 0.260 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.740 0.260 0.000
T51 Toxic effect of alcohol
0.736 0.264 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.736 0.264 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.735 0.265 0.000
I72 Other aneurysm
0.735 0.265 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.734 0.266 0.000
C20 Malignant neoplasm of rectum
0.732 0.268 0.000
I70 Atherosclerosis
0.731 0.269 0.000
C92 Myeloid leukaemia
0.731 0.269 0.000
D73 Diseases of spleen
0.730 0.269 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.730 0.270 0.000
D75.9 Disease of blood and blood-forming organs, unspecified
0.730 0.270 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.730 0.270 0.000
F80-F89 Disorders of psychological development
0.728 0.272 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.728 0.272 0.000
G30 Alzheimer's disease
0.727 0.273 0.000
I08.8 Other multiple valve diseases
0.724 0.275 0.000
G70-G73 Diseases of myoneural junction and muscle
0.724 0.276 0.000
N17-N19 Renal failure
0.724 0.276 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.723 0.277 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.722 0.278 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.722 0.278 0.000
J40 Bronchitis, not specified as acute or chronic
0.720 0.279 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.720 0.280 0.000
T39.0 Salicylates
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.716 0.284 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.716 0.284 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.716 0.284 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.716 0.284 0.000
G40.5 Special epileptic syndromes
0.716 0.284 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.716 0.284 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.716 0.284 0.000
G95 Other diseases of spinal cord
0.716 0.284 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.715 0.284 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.715 0.284 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.715 0.284 0.000
C67.2 Lateral wall of bladder
0.715 0.285 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.714 0.286 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.714 0.286 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.714 0.286 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.714 0.286 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.714 0.286 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.714 0.286 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.714 0.286 0.000
T36 Poisoning by systemic antibiotics
0.714 0.286 0.000
N18 Chronic renal failure
0.714 0.286 0.000
I27.0 Primary pulmonary hypertension
0.713 0.287 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.712 0.288 0.000
T87 Complications peculiar to reattachment and amputation
0.712 0.288 0.000
H55-H59 Other disorders of eye and adnexa
0.712 0.288 0.000
I84.3 External thrombosed haemorrhoids
0.711 0.289 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.711 0.289 0.000
D80-D89 Certain disorders involving the immune mechanism
0.709 0.290 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.709 0.291 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.709 0.291 0.000
N20-N23 Urolithiasis
0.709 0.291 0.000
G83 Other paralytic syndromes
0.708 0.292 0.000
G80 Infantile cerebral palsy
0.708 0.292 0.000
C88 Malignant immunoproliferative diseases
0.708 0.292 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.708 0.292 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.708 0.292 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.708 0.292 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.708 0.292 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.708 0.292 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.708 0.292 0.000
F11 Mental and behavioural disorders due to use of opioids
0.708 0.292 0.000
T82.3 Mechanical complication of other vascular grafts
0.707 0.293 0.000
S80-S89 Injuries to the knee and lower leg
0.706 0.294 0.000
S92 Fracture of foot, except ankle
0.706 0.294 0.000
I88 Nonspecific lymphadenitis
0.706 0.294 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.706 0.294 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.706 0.294 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.705 0.295 0.000
D74 Methaemoglobinaemia
0.705 0.295 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.705 0.295 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.705 0.295 0.000
J69 Pneumonitis due to solids and liquids
0.705 0.295 0.000
F10.9 Unspecified mental and behavioural disorder
0.704 0.296 0.000
F10.8 Other mental and behavioural disorders
0.704 0.296 0.000
F10.7 Residual and late-onset psychotic disorder
0.704 0.296 0.000
F10.6 Amnesic syndrome
0.704 0.296 0.000
F10.5 Psychotic disorder
0.704 0.296 0.000
D69.6 Thrombocytopenia, unspecified
0.702 0.298 0.000
G81.1 Spastic hemiplegia
0.700 0.300 0.000
G81.0 Flaccid hemiplegia
0.700 0.300 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.700 0.300 0.000
C25 Malignant neoplasm of pancreas
0.699 0.301 0.000
T43.2 Other and unspecified antidepressants
0.699 0.301 0.000
H60-H62 Diseases of external ear
0.699 0.301 0.000
G91.9 Hydrocephalus, unspecified
0.698 0.302 0.000
C60-C63 Malignant neoplasms of male genital organs
0.697 0.303 0.000
J01 Acute sinusitis
0.695 0.304 0.000
F38 Other mood [affective] disorders
0.695 0.305 0.000
F34 Persistent mood [affective] disorders
0.695 0.305 0.000
F30 Manic episode
0.695 0.305 0.000
F39 Unspecified mood [affective] disorder
0.695 0.305 0.000
C17 Malignant neoplasm of small intestine
0.694 0.306 0.000
Q60-Q64 Congenital malformations of the urinary system
0.694 0.306 0.000
G93.3 Postviral fatigue syndrome
0.694 0.306 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.693 0.307 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.692 0.308 0.000
I86 Varicose veins of other sites
0.691 0.308 0.000
G44 Other headache syndromes
0.690 0.310 0.000
C32 Malignant neoplasm of larynx
0.690 0.310 0.000
D68.2 Hereditary deficiency of other clotting factors
0.690 0.310 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.690 0.310 0.000
T39.1 4-Aminophenol derivatives
0.689 0.311 0.000
Q80-Q89 Other congenital malformations
0.687 0.312 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.687 0.313 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.686 0.314 0.000
N20 Calculus of kidney and ureter
0.685 0.315 0.000
T40.4 Other synthetic narcotics
0.685 0.315 0.000
C67.4 Posterior wall of bladder
0.683 0.317 0.000
C91 Lymphoid leukaemia
0.683 0.317 0.000
C07 Malignant neoplasm of parotid gland
0.683 0.317 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.683 0.317 0.000
G92 Toxic encephalopathy
0.683 0.317 0.000
G37 Other demyelinating diseases of central nervous system
0.681 0.318 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.681 0.319 0.000
D68.6 Other Thrombophilia
0.681 0.319 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.681 0.319 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.681 0.319 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.681 0.319 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.680 0.319 0.000
H80-H83 Diseases of inner ear
0.680 0.320 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.680 0.320 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.680 0.320 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.680 0.320 0.000
T78 Adverse effects, not elsewhere classified
0.679 0.321 0.000
D67 Hereditary factor IX deficiency
0.679 0.321 0.000
D66 Hereditary factor VIII deficiency
0.679 0.321 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.679 0.321 0.000
I85 Oesophageal varices
0.679 0.321 0.000
G24 Dystonia
0.679 0.321 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.678 0.322 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.678 0.322 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.678 0.322 0.000
D75.2 Essential thrombocytosis
0.677 0.322 0.000
I84.0 Internal thrombosed haemorrhoids
0.677 0.323 0.000
J02 Acute pharyngitis
0.677 0.323 0.000
I09 Other rheumatic heart diseases
0.675 0.325 0.000
I06 Rheumatic aortic valve diseases
0.675 0.325 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.675 0.325 0.000
F60.3 Emotionally unstable personality disorder
0.675 0.325 0.000
H53-H54 Visual disturbances and blindness
0.674 0.326 0.000
I81 Portal vein thrombosis
0.674 0.326 0.000
S00-S09 Injuries to the head
0.673 0.327 0.000
F99-F99 Unspecified mental disorder
0.673 0.327 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.673 0.327 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.672 0.327 0.000
G25.3 Myoclonus
0.672 0.328 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.672 0.328 0.000
C21.8 Overlapping lesion of rectum, anus and anal canal
0.671 0.329 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.671 0.329 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.671 0.329 0.000
T39.4 Antirheumatics, not elsewhere classified
0.671 0.329 0.000
T39.2 Pyrazolone derivatives
0.671 0.329 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.671 0.329 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.671 0.329 0.000
G45.4 Transient global amnesia
0.670 0.330 0.000
N20.0 Calculus of kidney
0.670 0.330 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.669 0.331 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.668 0.332 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.668 0.332 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.668 0.332 0.000
C31 Malignant neoplasm of accessory sinuses
0.668 0.332 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.668 0.332 0.000
C37 Malignant neoplasm of thymus
0.668 0.332 0.000
C33 Malignant neoplasm of trachea
0.668 0.332 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.668 0.332 0.000
C95 Leukaemia of unspecified cell type
0.668 0.332 0.000
C94 Other leukaemias of specified cell type
0.668 0.332 0.000
C93 Monocytic leukaemia
0.668 0.332 0.000
C86 Other specified types of T/NK-cell lymphoma
0.668 0.332 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.668 0.332 0.000
J98.1 Pulmonary collapse
0.665 0.335 0.000
S50-S59 Injuries to the elbow and forearm
0.665 0.335 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.664 0.335 0.000
D50-D53 Nutritional anaemias
0.664 0.336 0.000
G93.4 Encephalopathy, unspecified
0.663 0.337 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.662 0.338 0.000
J09-J18 Influenza and pneumonia
0.662 0.338 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.661 0.338 0.000
D68.8 Other specified coagulation defects
0.660 0.340 0.000
I05 Rheumatic mitral valve diseases
0.659 0.341 0.000
I67.8 Other specified cerebrovascular diseases
0.658 0.342 0.000
N18.9 Chronic renal failure, unspecified
0.658 0.342 0.000
I28 Other diseases of pulmonary vessels
0.658 0.342 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.657 0.343 0.000
C66 Malignant neoplasm of ureter
0.657 0.343 0.000
C65 Malignant neoplasm of renal pelvis
0.657 0.343 0.000
G91.1 Obstructive hydrocephalus
0.657 0.343 0.000
D45 Polycythaemia vera
0.657 0.343 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.657 0.343 0.000
T40.8 Lysergide [LSD]
0.657 0.343 0.000
T40.7 Cannabis (derivatives)
0.657 0.343 0.000
T40.6 Other and unspecified narcotics
0.657 0.343 0.000
T40.5 Cocaine
0.657 0.343 0.000
T40.3 Methadone
0.657 0.343 0.000
T40.1 Heroin
0.657 0.343 0.000
T40.0 Opium
0.657 0.343 0.000
N72 Inflammatory disease of cervix uteri
0.657 0.343 0.000
I99 Other and unspecified disorders of circulatory system
0.656 0.344 0.000
F32.8 Other depressive episodes
0.655 0.345 0.000
J90-J94 Other diseases of pleura
0.654 0.346 0.000
I84.4 External haemorrhoids with other complications
0.653 0.347 0.000
S68 Traumatic amputation of wrist and hand
0.652 0.348 0.000
S42 Fracture of shoulder and upper arm
0.652 0.348 0.000
I08.9 Multiple valve disease, unspecified
0.651 0.349 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.651 0.349 0.000
T51.0 Ethanol
0.649 0.351 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.648 0.352 0.000
X60-X84 Intentional self-harm
0.648 0.352 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.648 0.352 0.000
H93 Other disorders of ear, not elsewhere classified
0.647 0.353 0.000
D72.8 Other specified disorders of white blood cells
0.646 0.354 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.646 0.354 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.645 0.355 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.644 0.356 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.644 0.356 0.000
G62 Other polyneuropathies
0.643 0.356 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.643 0.357 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.643 0.357 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.643 0.357 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.643 0.357 0.000
C81 Hodgkin's disease
0.643 0.357 0.000
G30.9 Alzheimer's disease, unspecified
0.641 0.359 0.000
T45.0 Antiallergic and antiemetic drugs
0.641 0.359 0.000
G93.8 Other specified disorders of brain
0.641 0.359 0.000
F01 Vascular dementia
0.640 0.360 0.000
V40-V49 Car occupant injured in transport accident
0.640 0.360 0.000
D38.1 Trachea, bronchus and lung
0.639 0.361 0.000
F33.8 Other recurrent depressive disorders
0.639 0.361 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.639 0.361 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.639 0.361 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.639 0.361 0.000
J04 Acute laryngitis and tracheitis
0.639 0.361 0.000
G60 Hereditary and idiopathic neuropathy
0.639 0.361 0.000
C34.8 Overlapping lesion of bronchus and lung
0.638 0.362 0.000
C34.2 Middle lobe, bronchus or lung
0.638 0.362 0.000
C34.0 Main bronchus
0.638 0.362 0.000
J41 Simple and mucopurulent chronic bronchitis
0.638 0.362 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.638 0.362 0.000
G93.2 Benign intracranial hypertension
0.637 0.362 0.000
G96 Other disorders of central nervous system
0.636 0.364 0.000
T43.9 Psychotropic drug, unspecified
0.636 0.364 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.636 0.364 0.000
T43.6 Psychostimulants with abuse potential
0.636 0.364 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.636 0.364 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.636 0.364 0.000
G35 Multiple sclerosis
0.636 0.364 0.000
F03 Unspecified dementia
0.635 0.364 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.635 0.365 0.000
I07 Rheumatic tricuspid valve diseases
0.635 0.365 0.000
C67.5 Bladder neck
0.634 0.366 0.000
T86.1 Kidney transplant failure and rejection
0.633 0.367 0.000
N18.3 Chronic kidney disease, stage 3
0.633 0.367 0.000
C92.1 Chronic myeloid leukaemia
0.633 0.367 0.000
C21.0 Anus, unspecified
0.633 0.367 0.000
C16 Malignant neoplasm of stomach
0.632 0.368 0.000
G94.1 Hydrocephalus in neoplastic disease
0.632 0.368 0.000
D68.9 Coagulation defect, unspecified
0.630 0.370 0.000
S65 Injury of blood vessels at wrist and hand level
0.630 0.370 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.630 0.370 0.000
I73.9 Peripheral vascular disease, unspecified
0.630 0.370 0.000
C69 Malignant neoplasm of eye and adnexa
0.629 0.371 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.628 0.372 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.628 0.372 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.628 0.372 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.628 0.372 0.000
T83.2 Mechanical complication of graft of urinary organ
0.628 0.372 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.628 0.372 0.000
C23 Malignant neoplasm of gallbladder
0.628 0.372 0.000
C85.1 B-cell lymphoma, unspecified
0.627 0.372 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.627 0.373 0.000
H10-H13 Disorders of conjunctiva
0.626 0.374 0.000
J69.0 Pneumonitis due to food and vomit
0.626 0.374 0.000
J86 Pyothorax
0.626 0.374 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.626 0.374 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.625 0.375 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.624 0.376 0.000
F02 Dementia in other diseases classified elsewhere
0.624 0.376 0.000
F09 Unspecified organic or symptomatic mental disorder
0.624 0.376 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.624 0.376 0.000
H55 Nystagmus and other irregular eye movements
0.622 0.378 0.000
F68 Other disorders of adult personality and behaviour
0.622 0.378 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.622 0.378 0.000
F65 Disorders of sexual preference
0.622 0.378 0.000
F64 Gender identity disorders
0.622 0.378 0.000
F63 Habit and impulse disorders
0.622 0.378 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.622 0.378 0.000
F69 Unspecified disorder of adult personality and behaviour
0.622 0.378 0.000
F61 Mixed and other personality disorders
0.622 0.378 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.621 0.379 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.621 0.379 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.621 0.379 0.000
F60.9 Personality disorder, unspecified
0.621 0.379 0.000
I78 Diseases of capillaries
0.620 0.379 0.000
D68.5 Primary Thrombophilia
0.620 0.380 0.000
D68.4 Acquired coagulation factor deficiency
0.620 0.380 0.000
D68.1 Hereditary factor XI deficiency
0.620 0.380 0.000
D68.0 Von Willebrand's disease
0.620 0.380 0.000
I89.0 Lymphoedema, not elsewhere classified
0.618 0.382 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.618 0.382 0.000
Chapter XXI Factors influencing health status and contact with health services
0.618 0.382 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.618 0.382 0.000
Q35-Q37 Cleft lip and cleft palate
0.618 0.382 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.618 0.382 0.000
H90 Conductive and sensorineural hearing loss
0.617 0.382 0.000
H92 Otalgia and effusion of ear
0.617 0.383 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.616 0.383 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.616 0.384 0.000
G25.0 Essential tremor
0.616 0.384 0.000
I71 Aortic aneurysm and dissection
0.616 0.384 0.000
V01-V09 Pedestrian injured in transport accident
0.615 0.385 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.615 0.385 0.000
I95 Hypotension
0.615 0.385 0.000
D75.0 Familial erythrocytosis
0.615 0.385 0.000
H57 Other disorders of eye and adnexa
0.615 0.385 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.612 0.388 0.000
J20-J22 Other acute lower respiratory infections
0.611 0.389 0.000
S70 Superficial injury of hip and thigh
0.611 0.389 0.000
I77.5 Necrosis of artery
0.611 0.389 0.000
I77.4 Coeliac artery compression syndrome
0.611 0.389 0.000
I77.3 Arterial fibromuscular dysplasia
0.611 0.389 0.000
I77.2 Rupture of artery
0.611 0.389 0.000
I77.0 Arteriovenous fistula, acquired
0.611 0.389 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.611 0.389 0.000
H65-H75 Diseases of middle ear and mastoid
0.611 0.389 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.610 0.390 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.609 0.390 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.609 0.390 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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