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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77868089
log Bayes Factor = 15.3181
Chromosome 13   position 40,396,137  (GRCh37) Explore rs77868089 on Ensembl!
Variant rs77868089 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
Chapter X Diseases of the respiratory system
0.998 0.002 0.000
Chapter XXI Factors influencing health status and contact with health services
0.994 0.006 0.000
I30-I52 Other forms of heart disease
0.989 0.011 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.983 0.017 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.982 0.018 0.000
Chapter VI Diseases of the nervous system
0.981 0.019 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.981 0.019 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.979 0.021 0.000
Chapter II Neoplasms
0.979 0.021 0.000
S00-S09 Injuries to the head
0.977 0.023 0.000
I20-I25 Ischaemic heart diseases
0.976 0.024 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.973 0.027 0.000
Z94 Transplanted organ and tissue status
0.973 0.027 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.972 0.028 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.969 0.031 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.967 0.033 0.000
I42 Cardiomyopathy
0.966 0.034 0.000
Z51 Other medical care
0.962 0.038 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.960 0.040 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.959 0.041 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.955 0.045 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.953 0.047 0.000
I26 Pulmonary embolism
0.950 0.050 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.948 0.052 0.000
Z95.1 Presence of aortocoronary bypass graft
0.946 0.054 0.000
J90-J94 Other diseases of pleura
0.945 0.055 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.936 0.063 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.936 0.064 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.934 0.066 0.000
J00-J06 Acute upper respiratory infections
0.931 0.069 0.000
Z94.8 Other transplanted organ and tissue status
0.931 0.069 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.931 0.069 0.000
D60-D64 Aplastic and other anaemias
0.928 0.072 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.928 0.072 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.927 0.073 0.000
J09-J18 Influenza and pneumonia
0.924 0.076 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.921 0.079 0.000
S09 Other and unspecified injuries of head
0.921 0.079 0.000
Z94.0 Kidney transplant status
0.915 0.085 0.000
Z86.7 Personal history of diseases of the circulatory system
0.914 0.086 0.000
Z86 Personal history of certain other diseases
0.913 0.087 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.913 0.087 0.000
Y43 Primarily systemic agents
0.910 0.090 0.000
Z51.1 Chemotherapy session for neoplasm
0.907 0.093 0.000
I49 Other cardiac arrhythmias
0.905 0.095 0.000
Chapter I Certain infectious and parasitic diseases
0.904 0.096 0.000
Z80 Family history of malignant neoplasm
0.904 0.096 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.901 0.099 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.898 0.102 0.000
D64 Other anaemias
0.896 0.104 0.000
Y84.8 Other medical procedures
0.893 0.107 0.000
G90-G99 Other disorders of the nervous system
0.891 0.109 0.000
I05-I09 Chronic rheumatic heart diseases
0.889 0.111 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.888 0.112 0.000
I46 Cardiac arrest
0.888 0.112 0.000
Z29 Need for other prophylactic measures
0.888 0.112 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.886 0.114 0.000
I27 Other pulmonary heart diseases
0.884 0.116 0.000
I20 Angina pectoris
0.881 0.119 0.000
Z51.0 Radiotherapy session
0.880 0.120 0.000
C79 Secondary malignant neoplasm of other sites
0.876 0.124 0.000
I73 Other peripheral vascular diseases
0.875 0.125 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.875 0.125 0.000
Chapter VIII Diseases of the ear and mastoid process
0.874 0.126 0.000
Chapter XXII Codes for special purposes
0.874 0.126 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.873 0.127 0.000
W00-W19 Falls
0.873 0.127 0.000
I31 Other diseases of pericardium
0.872 0.128 0.000
S09.9 Unspecified injury of head
0.869 0.131 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.867 0.132 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.866 0.134 0.000
I24 Other acute ischaemic heart diseases
0.865 0.135 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.863 0.137 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.862 0.138 0.000
M25.5 Pain in joint
0.856 0.144 0.000
A30-A49 Other bacterial diseases
0.856 0.144 0.000
M20-M25 Other joint disorders
0.856 0.144 0.000
M25 Other joint disorders, not elsewhere classified
0.855 0.145 0.000
D10-D36 Benign neoplasms
0.854 0.146 0.000
I20.0 Unstable angina
0.852 0.148 0.000
D64.9 Anaemia, unspecified
0.851 0.149 0.000
S00 Superficial injury of head
0.851 0.149 0.000
J84 Other interstitial pulmonary diseases
0.850 0.150 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.849 0.151 0.000
I42.9 Cardiomyopathy, unspecified
0.849 0.151 0.000
G82 Paraplegia and tetraplegia
0.847 0.153 0.000
Z45 Adjustment and management of implanted device
0.846 0.154 0.000
D45 Polycythaemia vera
0.845 0.155 0.000
J20-J22 Other acute lower respiratory infections
0.843 0.157 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.843 0.157 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.839 0.161 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.839 0.161 0.000
J90 Pleural effusion, not elsewhere classified
0.836 0.164 0.000
I77 Other disorders of arteries and arterioles
0.835 0.165 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.835 0.165 0.000
I42.0 Dilated cardiomyopathy
0.835 0.165 0.000
I47 Paroxysmal tachycardia
0.835 0.165 0.000
O20 Haemorrhage in early pregnancy
0.829 0.171 0.000
D25 Leiomyoma of uterus
0.827 0.173 0.000
I25 Chronic ischaemic heart disease
0.825 0.175 0.000
M25.56 Pain in joint (Lower leg)
0.825 0.175 0.000
T91 Sequelae of injuries of neck and trunk
0.824 0.175 0.000
S80-S89 Injuries to the knee and lower leg
0.823 0.177 0.000
J00 Acute nasopharyngitis [common cold]
0.821 0.179 0.000
I73.9 Peripheral vascular disease, unspecified
0.821 0.179 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.820 0.180 0.000
Y43.3 Other antineoplastic drugs
0.820 0.180 0.000
H90-H95 Other disorders of ear
0.819 0.181 0.000
M86-M90 Other osteopathies
0.818 0.182 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.817 0.183 0.000
G95 Other diseases of spinal cord
0.816 0.184 0.000
Z29.2 Other prophylactic chemotherapy
0.816 0.184 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.815 0.185 0.000
W20-W49 Exposure to inanimate mechanical forces
0.814 0.186 0.000
Z51.3 Blood transfusion without reported diagnosis
0.813 0.187 0.000
S05 Injury of eye and orbit
0.812 0.188 0.000
Z51.9 Medical care, unspecified
0.811 0.189 0.000
Z89 Acquired absence of limb
0.810 0.190 0.000
J18 Pneumonia, organism unspecified
0.810 0.190 0.000
T86 Failure and rejection of transplanted organs and tissues
0.809 0.191 0.000
J92 Pleural plaque
0.809 0.191 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.808 0.192 0.000
D25.0 Submucous leiomyoma of uterus
0.807 0.193 0.000
Z94.4 Liver transplant status
0.806 0.194 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.806 0.194 0.000
I42.2 Other hypertrophic cardiomyopathy
0.803 0.196 0.000
O80-O84 Delivery
0.801 0.199 0.000
Z49 Care involving dialysis
0.801 0.199 0.000
Y44 Agents primarily affecting blood constituents
0.800 0.200 0.000
M25.57 Pain in joint (Ankle and foot)
0.800 0.200 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.799 0.201 0.000
I42.8 Other cardiomyopathies
0.797 0.203 0.000
Z51.5 Palliative care
0.797 0.203 0.000
S40-S49 Injuries to the shoulder and upper arm
0.795 0.205 0.000
I31.9 Disease of pericardium, unspecified
0.795 0.205 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.795 0.205 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.794 0.205 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.794 0.206 0.000
Y43.4 Immunosuppressive agents
0.793 0.207 0.000
Y40 Systemic antibiotics
0.793 0.207 0.000
I10-I15 Hypertensive diseases
0.792 0.208 0.000
T81 Complications of procedures, not elsewhere classified
0.790 0.210 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.789 0.211 0.000
G51 Facial nerve disorders
0.788 0.212 0.000
I70 Atherosclerosis
0.787 0.212 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.786 0.214 0.000
S90-S99 Injuries to the ankle and foot
0.785 0.215 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.783 0.217 0.000
J03 Acute tonsillitis
0.782 0.218 0.000
M15-M19 Arthrosis
0.781 0.219 0.000
J80 Adult respiratory distress syndrome
0.781 0.219 0.000
D61 Other aplastic anaemias
0.780 0.220 0.000
T92 Sequelae of injuries of upper limb
0.779 0.221 0.000
O00-O08 Pregnancy with abortive outcome
0.778 0.222 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.777 0.223 0.000
C51-C58 Malignant neoplasms of female genital organs
0.776 0.224 0.000
Y00-Y09 Assault
0.775 0.225 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.775 0.225 0.000
W50-W64 Exposure to animate mechanical forces
0.775 0.225 0.000
Z52 Donors of organs and tissues
0.774 0.226 0.000
I46.9 Cardiac arrest, unspecified
0.774 0.226 0.000
S10-S19 Injuries to the neck
0.773 0.227 0.000
O20.0 Threatened abortion
0.772 0.228 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.770 0.230 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.768 0.232 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.767 0.233 0.000
I27.2 Other secondary pulmonary hypertension
0.766 0.234 0.000
G82.2 Paraplegia, unspecified
0.765 0.235 0.000
Z85 Personal history of malignant neoplasm
0.765 0.235 0.000
I22 Subsequent myocardial infarction
0.763 0.236 0.000
D64.8 Other specified anaemias
0.763 0.237 0.000
I49.9 Cardiac arrhythmia, unspecified
0.763 0.237 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.762 0.238 0.000
I42.6 Alcoholic cardiomyopathy
0.761 0.239 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.761 0.239 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.760 0.240 0.000
Y86 Sequelae of other accidents
0.760 0.240 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.758 0.242 0.000
I08 Multiple valve diseases
0.758 0.242 0.000
C77.0 Lymph nodes of head, face and neck
0.757 0.243 0.000
I49.5 Sick sinus syndrome
0.757 0.243 0.000
Z45.8 Adjustment and management of other implanted devices
0.756 0.243 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.756 0.244 0.000
I36 Nonrheumatic tricuspid valve disorders
0.756 0.244 0.000
Y57 Other and unspecified drugs and medicaments
0.756 0.244 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.755 0.244 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.755 0.245 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.755 0.245 0.000
A49 Bacterial infection of unspecified site
0.755 0.245 0.000
I72 Other aneurysm
0.753 0.247 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.752 0.248 0.000
Q28 Other congenital malformations of circulatory system
0.752 0.248 0.000
Q21 Congenital malformations of cardiac septa
0.752 0.248 0.000
W08 Fall involving other furniture
0.751 0.249 0.000
I24.8 Other forms of acute ischaemic heart disease
0.749 0.251 0.000
D80-D89 Certain disorders involving the immune mechanism
0.748 0.252 0.000
S02 Fracture of skull and facial bones
0.747 0.253 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.747 0.253 0.000
W10 Fall on and from stairs and steps
0.747 0.253 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.746 0.254 0.000
X60-X84 Intentional self-harm
0.745 0.255 0.000
A41 Other septicaemia
0.745 0.255 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.745 0.255 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.743 0.256 0.000
M05-M14 Inflammatory polyarthropathies
0.743 0.257 0.000
Z29.8 Other specified prophylactic measures
0.742 0.258 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.742 0.258 0.000
Z81 Family history of mental and behavioural disorders
0.740 0.260 0.000
V80-V89 Other land transport accidents
0.740 0.260 0.000
Z51.8 Other specified medical care
0.740 0.260 0.000
G95.2 Cord compression, unspecified
0.738 0.262 0.000
J22 Unspecified acute lower respiratory infection
0.737 0.263 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.737 0.263 0.000
T66-T78 Other and unspecified effects of external causes
0.737 0.263 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.736 0.264 0.000
M80-M85 Disorders of bone density and structure
0.736 0.264 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.735 0.265 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.733 0.267 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.733 0.267 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.732 0.268 0.000
J86 Pyothorax
0.731 0.269 0.000
Z94.7 Corneal transplant status
0.731 0.269 0.000
S00.8 Superficial injury of other parts of head
0.731 0.269 0.000
I74 Arterial embolism and thrombosis
0.730 0.270 0.000
J02 Acute pharyngitis
0.730 0.270 0.000
J93 Pneumothorax
0.730 0.270 0.000
I05 Rheumatic mitral valve diseases
0.729 0.271 0.000
I25.5 Ischaemic cardiomyopathy
0.728 0.272 0.000
I46.0 Cardiac arrest with successful resuscitation
0.728 0.272 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.727 0.273 0.000
I47.2 Ventricular tachycardia
0.727 0.273 0.000
D73 Diseases of spleen
0.727 0.273 0.000
Q60-Q64 Congenital malformations of the urinary system
0.726 0.273 0.000
G57 Mononeuropathies of lower limb
0.725 0.275 0.000
O24 Diabetes mellitus in pregnancy
0.725 0.275 0.000
J94 Other pleural conditions
0.724 0.275 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.724 0.276 0.000
Y52 Agents primarily affecting the cardiovascular system
0.724 0.276 0.000
G90 Disorders of autonomic nervous system
0.723 0.277 0.000
I20.1 Angina pectoris with documented spasm
0.722 0.278 0.000
Y84.1 Kidney dialysis
0.722 0.278 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.721 0.279 0.000
S06 Intracranial injury
0.721 0.279 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.721 0.279 0.000
J92.0 Pleural plaque with presence of asbestos
0.718 0.282 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.718 0.282 0.000
O85-O92 Complications predominantly related to the puerperium
0.718 0.282 0.000
S09.8 Other specified injuries of head
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I12 Hypertensive renal disease
0.717 0.283 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.717 0.283 0.000
T87 Complications peculiar to reattachment and amputation
0.717 0.283 0.000
M89 Other disorders of bone
0.717 0.283 0.000
I50 Heart failure
0.716 0.284 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X50-X57 Overexertion, travel and privation
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X20-X29 Contact with venomous animals and plants
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V40-V49 Car occupant injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.715 0.285 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.715 0.285 0.000
G30-G32 Other degenerative diseases of the nervous system
0.714 0.286 0.000
J11 Influenza, virus not identified
0.713 0.287 0.000
S00.5 Superficial injury of lip and oral cavity
0.712 0.288 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.712 0.288 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.712 0.288 0.000
C34 Malignant neoplasm of bronchus and lung
0.709 0.291 0.000
I52 Other heart disorders in diseases classified elsewhere
0.709 0.291 0.000
I48 Atrial fibrillation and flutter
0.709 0.291 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.709 0.291 0.000
I41 Myocarditis in diseases classified elsewhere
0.709 0.291 0.000
I40 Acute myocarditis
0.709 0.291 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.709 0.291 0.000
I37 Pulmonary valve disorders
0.709 0.291 0.000
I32 Pericarditis in diseases classified elsewhere
0.709 0.291 0.000
I30 Acute pericarditis
0.709 0.291 0.000
H91 Other hearing loss
0.709 0.291 0.000
Z40 Prophylactic surgery
0.708 0.292 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.707 0.293 0.000
M25.0 Haemarthrosis
0.707 0.293 0.000
J10 Influenza due to identified influenza virus
0.706 0.294 0.000
S80 Superficial injury of lower leg
0.706 0.294 0.000
I28 Other diseases of pulmonary vessels
0.705 0.295 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.705 0.295 0.000
I49.4 Other and unspecified premature depolarisation
0.705 0.295 0.000
H65-H75 Diseases of middle ear and mastoid
0.705 0.295 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.704 0.296 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.704 0.296 0.000
T82.3 Mechanical complication of other vascular grafts
0.704 0.296 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.704 0.296 0.000
G54 Nerve root and plexus disorders
0.704 0.296 0.000
G82.5 Tetraplegia, unspecified
0.704 0.296 0.000
T93 Sequelae of injuries of lower limb
0.704 0.296 0.000
Q27 Other congenital malformations of peripheral vascular system
0.703 0.297 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.703 0.297 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.703 0.297 0.000
Z80.6 Family history of leukaemia
0.703 0.297 0.000
G70-G73 Diseases of myoneural junction and muscle
0.703 0.297 0.000
C45 Mesothelioma
0.703 0.297 0.000
Z84 Family history of other conditions
0.702 0.298 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.702 0.298 0.000
D35.2 Pituitary gland
0.702 0.298 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.702 0.298 0.000
S08 Traumatic amputation of part of head
0.701 0.299 0.000
S07 Crushing injury of head
0.701 0.299 0.000
S04 Injury of cranial nerves
0.701 0.299 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.701 0.299 0.000
M18 Arthrosis of first carpometacarpal joint
0.700 0.300 0.000
I23 Certain current complications following acute myocardial infarction
0.700 0.300 0.000
S20-S29 Injuries to the thorax
0.699 0.300 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.699 0.301 0.000
D62 Acute posthaemorrhagic anaemia
0.699 0.301 0.000
M91-M94 Chondropathies
0.699 0.301 0.000
T91.3 Sequelae of injury of spinal cord
0.699 0.301 0.000
D16 Benign neoplasm of bone and articular cartilage
0.698 0.302 0.000
Z94.9 Transplanted organ and tissue status, unspecified
0.697 0.302 0.000
Z94.6 Bone transplant status
0.697 0.302 0.000
Z94.5 Skin transplant status
0.697 0.302 0.000
Z94.3 Heart and lungs transplant status
0.697 0.302 0.000
Z94.2 Lung transplant status
0.697 0.302 0.000
Z94.1 Heart transplant status
0.697 0.302 0.000
I25.2 Old myocardial infarction
0.697 0.303 0.000
I27.0 Primary pulmonary hypertension
0.697 0.303 0.000
Z44 Fitting and adjustment of external prosthetic device
0.697 0.303 0.000
D25.2 Subserosal leiomyoma of uterus
0.697 0.303 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.696 0.304 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.696 0.304 0.000
H93 Other disorders of ear, not elsewhere classified
0.696 0.304 0.000
H92 Otalgia and effusion of ear
0.695 0.305 0.000
J18.1 Lobar pneumonia, unspecified
0.693 0.307 0.000
Y43.1 Antineoplastic antimetabolites
0.693 0.307 0.000
I49.3 Ventricular premature depolarisation
0.693 0.307 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.693 0.307 0.000
T82.1 Mechanical complication of cardiac electronic device
0.693 0.307 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.693 0.307 0.000
I42.5 Other restrictive cardiomyopathy
0.693 0.307 0.000
I42.4 Endocardial fibroelastosis
0.693 0.307 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.693 0.307 0.000
I60-I69 Cerebrovascular diseases
0.692 0.308 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.691 0.309 0.000
J14 Pneumonia due to Haemophilus influenzae
0.690 0.310 0.000
Z54 Convalescence
0.689 0.310 0.000
Z51.6 Desensitisation to allergens
0.689 0.311 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.689 0.311 0.000
D55-D59 Haemolytic anaemias
0.688 0.311 0.000
Z97 Presence of other devices
0.688 0.312 0.000
Y59 Other and unspecified vaccines and biological substances
0.688 0.312 0.000
Y58 Bacterial vaccines
0.688 0.312 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.688 0.312 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.688 0.312 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.688 0.312 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.688 0.312 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.688 0.312 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.688 0.312 0.000
Y48 Anaesthetics and therapeutic gases
0.688 0.312 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.688 0.312 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.688 0.312 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.688 0.312 0.000
Y44.2 Anticoagulants
0.686 0.314 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.686 0.314 0.000
Z29.0 Isolation
0.686 0.314 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.686 0.314 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.685 0.315 0.000
Q00-Q07 Congenital malformations of the nervous system
0.685 0.315 0.000
D36 Benign neoplasm of other and unspecified sites
0.685 0.315 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.684 0.316 0.000
T85.2 Mechanical complication of intraocular lens
0.683 0.316 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.683 0.317 0.000
S50-S59 Injuries to the elbow and forearm
0.683 0.317 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.683 0.317 0.000
M25.53 Pain in joint (Forearm)
0.682 0.318 0.000
G51.0 Bell's palsy
0.682 0.318 0.000
J84.8 Other specified interstitial pulmonary diseases
0.682 0.318 0.000
I27.9 Pulmonary heart disease, unspecified
0.682 0.318 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.681 0.318 0.000
T90 Sequelae of injuries of head
0.681 0.319 0.000
J60-J70 Lung diseases due to external agents
0.680 0.320 0.000
G03 Meningitis due to other and unspecified causes
0.679 0.321 0.000
I21 Acute myocardial infarction
0.679 0.321 0.000
D37.4 Colon
0.679 0.321 0.000
D31 Benign neoplasm of eye and adnexa
0.679 0.321 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.678 0.322 0.000
Z95.2 Presence of prosthetic heart valve
0.678 0.322 0.000
J04 Acute laryngitis and tracheitis
0.678 0.322 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.678 0.322 0.000
G83 Other paralytic syndromes
0.677 0.323 0.000
M25.51 Pain in joint (Shoulder region)
0.677 0.323 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.677 0.323 0.000
A40 Streptococcal septicaemia
0.676 0.324 0.000
D26 Other benign neoplasms of uterus
0.676 0.324 0.000
G93 Other disorders of brain
0.675 0.325 0.000
I78 Diseases of capillaries
0.675 0.325 0.000
J03.9 Acute tonsillitis, unspecified
0.675 0.325 0.000
Z99.2 Dependence on renal dialysis
0.675 0.325 0.000
D72 Other disorders of white blood cells
0.675 0.325 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.675 0.325 0.000
O03 Spontaneous abortion
0.675 0.325 0.000
M25.59 Pain in joint (Site unspecified)
0.675 0.325 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.674 0.325 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.674 0.326 0.000
S05.8 Other injuries of eye and orbit
0.673 0.326 0.000
D61.9 Aplastic anaemia, unspecified
0.673 0.327 0.000
M15 Polyarthrosis
0.673 0.327 0.000
O80 Single spontaneous delivery
0.673 0.327 0.000
B15-B19 Viral hepatitis
0.672 0.328 0.000
B35-B49 Mycoses
0.672 0.328 0.000
T79-T79 Certain early complications of trauma
0.672 0.328 0.000
D46 Myelodysplastic syndromes
0.672 0.328 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.672 0.328 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.671 0.328 0.000
Q80-Q89 Other congenital malformations
0.671 0.328 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.671 0.328 0.000
Q35-Q37 Cleft lip and cleft palate
0.671 0.328 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.671 0.328 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.671 0.328 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.671 0.329 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.671 0.329 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.671 0.329 0.000
I12.0 Hypertensive renal disease with renal failure
0.671 0.329 0.000
J95-J99 Other diseases of the respiratory system
0.670 0.330 0.000
Z28 Immunisation not carried out
0.670 0.330 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.670 0.330 0.000
Z26 Need for immunisation against other single infectious diseases
0.670 0.330 0.000
Z25 Need for immunisation against other single viral diseases
0.670 0.330 0.000
Z24 Need for immunisation against certain single viral diseases
0.670 0.330 0.000
Z23 Need for immunisation against single bacterial diseases
0.670 0.330 0.000
Z20 Contact with and exposure to communicable diseases
0.670 0.330 0.000
D75 Other diseases of blood and blood-forming organs
0.669 0.331 0.000
J91 Pleural effusion in conditions classified elsewhere
0.668 0.331 0.000
B65-B83 Helminthiases
0.668 0.332 0.000
M00-M03 Infectious arthropathies
0.668 0.332 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.668 0.332 0.000
Z95.4 Presence of other heart-valve replacement
0.668 0.332 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.667 0.332 0.000
J01 Acute sinusitis
0.667 0.332 0.000
T98 Sequelae of other and unspecified effects of external causes
0.667 0.333 0.000
T95 Sequelae of burns, corrosions and frostbite
0.667 0.333 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.667 0.333 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.667 0.333 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.667 0.333 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.667 0.333 0.000
G82.1 Spastic paraplegia
0.667 0.333 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.666 0.334 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.666 0.334 0.000
I77.1 Stricture of artery
0.666 0.334 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.666 0.334 0.000
I49.8 Other specified cardiac arrhythmias
0.664 0.335 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.664 0.336 0.000
Q28.2 Arteriovenous malformation of cerebral vessels
0.664 0.336 0.000
Q21.1 Atrial septal defect
0.664 0.336 0.000
Y40.0 Penicillins
0.664 0.336 0.000
W08.0 Home
0.663 0.337 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.663 0.337 0.000
J17 Pneumonia in diseases classified elsewhere
0.662 0.338 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.662 0.338 0.000
J12 Viral pneumonia, not elsewhere classified
0.662 0.338 0.000
J09 Influenza due to certain identified influenza virus
0.662 0.338 0.000
Q50-Q56 Congenital malformations of genital organs
0.662 0.338 0.000
C77.8 Lymph nodes of multiple regions
0.661 0.338 0.000
T91.1 Sequelae of fracture of spine
0.661 0.339 0.000
G95.9 Disease of spinal cord, unspecified
0.661 0.339 0.000
G80 Infantile cerebral palsy
0.661 0.339 0.000
J18.0 Bronchopneumonia, unspecified
0.661 0.339 0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection
0.661 0.339 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.661 0.339 0.000
C77.5 Intrapelvic lymph nodes
0.660 0.340 0.000
S09.7 Multiple injuries of head
0.660 0.340 0.000
S09.2 Traumatic rupture of ear drum
0.660 0.340 0.000
S09.1 Injury of muscle and tendon of head
0.660 0.340 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.660 0.340 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.660 0.340 0.000
A49.0 Staphylococcal infection, unspecified
0.660 0.340 0.000
G58 Other mononeuropathies
0.659 0.340 0.000
S00.7 Multiple superficial injuries of head
0.659 0.341 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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