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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2845885
log Bayes Factor = 4.30722
Chromosome 11   position 63,869,062  (GRCh37) Explore rs2845885 on Ensembl!
Variant rs2845885 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I10 Essential (primary) hypertension
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.001 0.999
I10-I15 Hypertensive diseases
0.000 0.001 0.999
I20-I25 Ischaemic heart diseases
0.000 0.005 0.995
I60-I69 Cerebrovascular diseases
0.000 0.010 0.990
I25 Chronic ischaemic heart disease
0.000 0.014 0.986
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.029 0.971
I30-I52 Other forms of heart disease
0.000 0.039 0.961
I21 Acute myocardial infarction
0.000 0.047 0.953
I21.4 Acute subendocardial myocardial infarction
0.000 0.060 0.940
I44 Atrioventricular and left bundle-branch block
0.000 0.078 0.922
I67 Other cerebrovascular diseases
0.000 0.089 0.911
I42 Cardiomyopathy
0.000 0.098 0.902
I61 Intracerebral haemorrhage
0.000 0.120 0.880
I44.7 Left bundle-branch block, unspecified
0.000 0.123 0.877
I63 Cerebral infarction
0.000 0.125 0.875
I69 Sequelae of cerebrovascular disease
0.000 0.127 0.873
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.136 0.864
I05-I09 Chronic rheumatic heart diseases
0.000 0.138 0.862
I22 Subsequent myocardial infarction
0.000 0.165 0.835
I67.9 Cerebrovascular disease, unspecified
0.000 0.169 0.831
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.170 0.830
I45 Other conduction disorders
0.000 0.173 0.827
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.193 0.807
I30 Acute pericarditis
0.000 0.200 0.800
I25.1 Atherosclerotic heart disease
0.000 0.218 0.782
I44.1 Atrioventricular block, second degree
0.000 0.226 0.774
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.238 0.762
I42.8 Other cardiomyopathies
0.000 0.245 0.755
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.245 0.755
I25.3 Aneurysm of heart
0.000 0.247 0.753
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.249 0.751
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.252 0.748
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.258 0.742
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.260 0.740
I44.0 Atrioventricular block, first degree
0.000 0.261 0.739
I45.2 Bifascicular block
0.000 0.263 0.737
I69.3 Sequelae of cerebral infarction
0.000 0.263 0.737
I25.6 Silent myocardial ischaemia
0.000 0.269 0.730
I37 Pulmonary valve disorders
0.000 0.272 0.728
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.274 0.726
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.276 0.724
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.276 0.724
I08 Multiple valve diseases
0.000 0.277 0.723
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.277 0.723
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.278 0.722
I13 Hypertensive heart and renal disease
0.000 0.278 0.722
I06 Rheumatic aortic valve diseases
0.000 0.279 0.721
I49 Other cardiac arrhythmias
0.000 0.280 0.720
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.281 0.719
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.283 0.717
I67.8 Other specified cerebrovascular diseases
0.000 0.283 0.717
I42.9 Cardiomyopathy, unspecified
0.000 0.284 0.716
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.284 0.716
I86 Varicose veins of other sites
0.000 0.284 0.716
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.286 0.714
I23 Certain current complications following acute myocardial infarction
0.000 0.287 0.713
I35 Nonrheumatic aortic valve disorders
0.000 0.288 0.712
I42.2 Other hypertrophic cardiomyopathy
0.000 0.293 0.707
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.295 0.705
I42.5 Other restrictive cardiomyopathy
0.000 0.302 0.698
I00-I02 Acute rheumatic fever
0.000 0.303 0.697
I61.8 Other intracerebral haemorrhage
0.000 0.303 0.697
I40 Acute myocarditis
0.000 0.303 0.697
I42.4 Endocardial fibroelastosis
0.000 0.305 0.695
I25.4 Coronary artery aneurysm
0.000 0.306 0.694
I46 Cardiac arrest
0.000 0.306 0.694
I52 Other heart disorders in diseases classified elsewhere
0.000 0.311 0.689
I48 Atrial fibrillation and flutter
0.000 0.311 0.689
I41 Myocarditis in diseases classified elsewhere
0.000 0.311 0.689
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.311 0.689
I32 Pericarditis in diseases classified elsewhere
0.000 0.311 0.689
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.316 0.684
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.318 0.682
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.318 0.682
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.319 0.681
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.319 0.680
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.320 0.680
I85 Oesophageal varices
0.000 0.320 0.679
I49.0 Ventricular fibrillation and flutter
0.000 0.325 0.675
I50 Heart failure
0.000 0.327 0.673
I86.4 Gastric varices
0.000 0.328 0.672
I44.4 Left anterior fascicular block
0.000 0.330 0.670
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.333 0.667
I45.6 Preexcitation syndrome
0.000 0.334 0.666
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.335 0.665
I15 Secondary hypertension
0.000 0.336 0.664
I44.3 Other and unspecified atrioventricular block
0.000 0.336 0.664
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.339 0.661
I44.5 Left posterior fascicular block
0.000 0.339 0.661
I62 Other nontraumatic intracranial haemorrhage
0.000 0.341 0.659
I30.1 Infective pericarditis
0.000 0.342 0.658
I67.2 Cerebral atherosclerosis
0.000 0.344 0.656
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.345 0.655
I67.5 Moyamoya disease
0.000 0.346 0.653
I67.3 Progressive vascular leukoencephalopathy
0.000 0.346 0.653
I42.6 Alcoholic cardiomyopathy
0.000 0.348 0.652
I25.2 Old myocardial infarction
0.000 0.350 0.650
I36 Nonrheumatic tricuspid valve disorders
0.000 0.350 0.649
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.353 0.647
I11 Hypertensive heart disease
0.000 0.356 0.644
I50.9 Heart failure, unspecified
0.000 0.362 0.638
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.363 0.637
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.365 0.635
I67.4 Hypertensive encephalopathy
0.000 0.366 0.634
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.366 0.634
I26 Pulmonary embolism
0.000 0.369 0.631
I31 Other diseases of pericardium
0.000 0.369 0.631
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.372 0.628
I45.5 Other specified heart block
0.000 0.373 0.627
I09 Other rheumatic heart diseases
0.000 0.374 0.626
I65.2 Occlusion and stenosis of carotid artery
0.000 0.375 0.625
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.380 0.619
I60 Subarachnoid haemorrhage
0.000 0.381 0.619
I45.0 Right fascicular block
0.000 0.384 0.615
I05 Rheumatic mitral valve diseases
0.000 0.390 0.610
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.391 0.609
I25.5 Ischaemic cardiomyopathy
0.000 0.394 0.606
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.394 0.606
I85.0 Oesophageal varices with bleeding
0.000 0.394 0.606
I44.6 Other and unspecified fascicular block
0.000 0.395 0.605
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.396 0.604
I65.1 Occlusion and stenosis of basilar artery
0.000 0.397 0.603
I30.8 Other forms of acute pericarditis
0.000 0.399 0.601
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.400 0.600
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.400 0.600
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.401 0.599
I49.1 Atrial premature depolarisation
0.000 0.408 0.592
I67.1 Cerebral aneurysm, nonruptured
0.000 0.409 0.591
I45.8 Other specified conduction disorders
0.000 0.409 0.591
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.409 0.590
I86.1 Scrotal varices
0.000 0.410 0.590
I30.9 Acute pericarditis, unspecified
0.000 0.410 0.590
I22.8 Subsequent myocardial infarction of other sites
0.000 0.410 0.590
I08.8 Other multiple valve diseases
0.000 0.410 0.590
I86.8 Varicose veins of other specified sites
0.000 0.412 0.588
I63.8 Other cerebral infarction
0.000 0.416 0.584
I88 Nonspecific lymphadenitis
0.000 0.416 0.584
I47 Paroxysmal tachycardia
0.000 0.419 0.581
I33 Acute and subacute endocarditis
0.000 0.419 0.581
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.420 0.580
I08.0 Disorders of both mitral and aortic valves
0.000 0.421 0.579
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.421 0.578
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.423 0.577
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.426 0.573
I63.9 Cerebral infarction, unspecified
0.000 0.427 0.573
I44.2 Atrioventricular block, complete
0.000 0.430 0.570
I24 Other acute ischaemic heart diseases
0.000 0.431 0.569
I45.1 Other and unspecified right bundle-branch block
0.000 0.432 0.568
I37.1 Pulmonary valve insufficiency
0.000 0.433 0.567
I83 Varicose veins of lower extremities
0.000 0.434 0.566
I42.0 Dilated cardiomyopathy
0.000 0.437 0.563
I45.3 Trifascicular block
0.000 0.438 0.562
I45.4 Nonspecific intraventricular block
0.000 0.439 0.561
I07 Rheumatic tricuspid valve diseases
0.000 0.441 0.559
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.441 0.559
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.442 0.557
I35.9 Aortic valve disorder, unspecified
0.000 0.443 0.557
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.444 0.556
I85.9 Oesophageal varices without bleeding
0.000 0.448 0.552
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.450 0.549
I06.0 Rheumatic aortic stenosis
0.000 0.451 0.549
I06.1 Rheumatic aortic insufficiency
0.000 0.451 0.549
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.451 0.548
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.453 0.547
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.454 0.546
I35.0 Aortic (valve) stenosis
0.000 0.459 0.541
I49.3 Ventricular premature depolarisation
0.000 0.459 0.540
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.465 0.534
I68.0 Cerebral amyloid angiopathy
0.000 0.467 0.533
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.468 0.532
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.469 0.531
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.469 0.531
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.471 0.529
I23.8 Other current complications following acute myocardial infarction
0.000 0.476 0.524
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.477 0.523
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.477 0.523
I37.9 Pulmonary valve disorder, unspecified
0.000 0.478 0.522
I37.8 Other pulmonary valve disorders
0.000 0.478 0.522
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.478 0.522
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.479 0.521
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.479 0.521
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.481 0.519
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.481 0.519
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.481 0.519
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.482 0.518
I06.8 Other rheumatic aortic valve diseases
0.000 0.483 0.517
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.483 0.517
I49.2 Junctional premature depolarisation
0.000 0.483 0.517
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.484 0.516
I28 Other diseases of pulmonary vessels
0.000 0.484 0.516
I46.9 Cardiac arrest, unspecified
0.000 0.485 0.515
I37.0 Pulmonary valve stenosis
0.000 0.487 0.513
I86.0 Sublingual varices
0.000 0.487 0.513
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.489 0.511
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.489 0.511
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.489 0.511
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.489 0.511
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.489 0.511
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.489 0.511
I40.9 Acute myocarditis, unspecified
0.000 0.489 0.510
I45.9 Conduction disorder, unspecified
0.000 0.493 0.506
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.495 0.504
I46.0 Cardiac arrest with successful resuscitation
0.000 0.500 0.500
I02 Rheumatic chorea
0.000 0.500 0.500
I01 Rheumatic fever with heart involvement
0.000 0.500 0.500
I40.8 Other acute myocarditis
0.000 0.500 0.499
I40.1 Isolated myocarditis
0.000 0.500 0.499
I12 Hypertensive renal disease
0.000 0.502 0.498
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.504 0.496
I40.0 Infective myocarditis
0.000 0.504 0.496
I49.5 Sick sinus syndrome
0.000 0.506 0.494
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.506 0.494
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.506 0.494
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.506 0.494
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.506 0.494
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.506 0.494
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.506 0.494
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.506 0.494
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.506 0.494
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.506 0.494
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.506 0.494
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.506 0.494
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.506 0.494
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.506 0.494
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.506 0.494
I48.4 Atypical atrial flutter
0.000 0.506 0.494
I48.3 Typical atrial flutter
0.000 0.506 0.494
I48.2 Chronic atrial fibrillation
0.000 0.506 0.494
I48.1 Persistent atrial fibrillation
0.000 0.506 0.494
I48.0 Paroxysmal atrial fibrillation
0.000 0.506 0.494
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.506 0.494
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.506 0.494
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.506 0.494
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.506 0.494
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.507 0.493
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.509 0.491
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.509 0.491
I08.9 Multiple valve disease, unspecified
0.000 0.509 0.491
I15.1 Hypertension secondary to other renal disorders
0.000 0.510 0.489
I31.3 Pericardial effusion (noninflammatory)
0.000 0.511 0.489
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.512 0.488
I27 Other pulmonary heart diseases
0.000 0.515 0.485
I86.2 Pelvic varices
0.000 0.516 0.484
I62.1 Nontraumatic extradural haemorrhage
0.000 0.518 0.482
I00 Rheumatic fever without mention of heart involvement
0.000 0.519 0.481
I31.0 Chronic adhesive pericarditis
0.000 0.519 0.480
I46.1 Sudden cardiac death, so described
0.000 0.520 0.480
I87 Other disorders of veins
0.000 0.521 0.479
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.521 0.478
I05.9 Mitral valve disease, unspecified
0.000 0.522 0.478
I15.8 Other secondary hypertension
0.000 0.522 0.477
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.522 0.477
I35.1 Aortic (valve) insufficiency
0.000 0.523 0.477
I86.3 Vulval varices
0.000 0.523 0.476
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.524 0.475
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.526 0.473
I47.0 Reentry ventricular arrhythmia
0.000 0.528 0.472
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.529 0.470
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.530 0.469
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.534 0.466
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.534 0.466
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.534 0.466
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.534 0.466
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.535 0.464
I15.9 Seconday hypertension, unspecified
0.000 0.538 0.462
I88.8 Other nonspecific lymphadenitis
0.000 0.541 0.459
I15.2 Hypertension secondary to endocrine disorders
0.000 0.542 0.457
I09.9 Rheumatic heart disease, unspecified
0.000 0.543 0.457
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.543 0.457
I38 Endocarditis, valve unspecified
0.000 0.543 0.456
I35.8 Other aortic valve disorders
0.000 0.545 0.454
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.546 0.454
I31.8 Other specified diseases of pericardium
0.000 0.547 0.452
I31.2 Haemopericardium, not elsewhere classified
0.000 0.547 0.452
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.549 0.451
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.549 0.451
I05.0 Mitral stenosis
0.000 0.550 0.450
I09.8 Other specified rheumatic heart diseases
0.000 0.551 0.449
I09.2 Chronic rheumatic pericarditis
0.000 0.551 0.449
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.551 0.449
I09.0 Rheumatic myocarditis
0.000 0.551 0.449
I34 Nonrheumatic mitral valve disorders
0.000 0.552 0.448
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.556 0.444
I15.0 Renovascular hypertension
0.000 0.557 0.443
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.563 0.436
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.567 0.433
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.567 0.433
I98.0 Cardiovascular syphilis
0.000 0.567 0.433
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.569 0.431
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.573 0.426
I47.2 Ventricular tachycardia
0.000 0.575 0.425
N63 Unspecified lump in breast
0.424 0.576 0.000
I05.1 Rheumatic mitral insufficiency
0.000 0.576 0.424
I05.8 Other mitral valve diseases
0.000 0.580 0.420
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.580 0.420
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.580 0.420
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.580 0.420
I99 Other and unspecified disorders of circulatory system
0.000 0.582 0.418
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.583 0.417
N60-N64 Disorders of breast
0.414 0.586 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.589 0.411
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.590 0.410
I24.1 Dressler's syndrome
0.000 0.592 0.408
I81 Portal vein thrombosis
0.000 0.592 0.407
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.594 0.406
I49.4 Other and unspecified premature depolarisation
0.000 0.594 0.406
I31.1 Chronic constrictive pericarditis
0.000 0.595 0.404
I82 Other venous embolism and thrombosis
0.000 0.596 0.404
N62 Hypertrophy of breast
0.404 0.596 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.596 0.404
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.597 0.403
I60.8 Other subarachnoid haemorrhage
0.000 0.598 0.402
I07.9 Tricuspid valve disease, unspecified
0.000 0.599 0.401
I07.8 Other tricuspid valve diseases
0.000 0.599 0.401
I07.2 Tricuspid stenosis with insufficiency
0.000 0.599 0.401
I07.0 Tricuspid stenosis
0.000 0.599 0.401
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.601 0.399
I33.9 Acute endocarditis, unspecified
0.000 0.601 0.398
I05.2 Mitral stenosis with insufficiency
0.000 0.604 0.396
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.605 0.395
I51 Complications and ill-defined descriptions of heart disease
0.000 0.610 0.390
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.614 0.385
I27.8 Other specified pulmonary heart diseases
0.000 0.617 0.382
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.623 0.376
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.627 0.372
I21.9 Acute myocardial infarction, unspecified
0.000 0.629 0.371
I28.1 Aneurysm of pulmonary artery
0.000 0.630 0.370
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.641 0.358
I01.8 Other acute rheumatic heart disease
0.000 0.641 0.358
I01.2 Acute rheumatic myocarditis
0.000 0.641 0.358
I01.1 Acute rheumatic endocarditis
0.000 0.641 0.358
I01.0 Acute rheumatic pericarditis
0.000 0.641 0.358
I02.9 Rheumatic chorea without heart involvement
0.000 0.641 0.358
I02.0 Rheumatic chorea with heart involvement
0.000 0.641 0.358
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.643 0.357
I12.9 Hypertensive renal disease without renal failure
0.000 0.643 0.356
N60 Benign mammary dysplasia
0.356 0.644 0.000
I28.8 Other specified diseases of pulmonary vessels
0.000 0.645 0.355
I97.0 Postcardiotomy syndrome
0.000 0.645 0.355
N64 Other disorders of breast
0.354 0.646 0.000
I27.9 Pulmonary heart disease, unspecified
0.000 0.647 0.353
I31.9 Disease of pericardium, unspecified
0.000 0.647 0.353
I87.8 Other specified disorders of veins
0.000 0.649 0.351
I87.1 Compression of vein
0.000 0.649 0.351
I27.1 Kyphoscoliotic heart disease
0.000 0.652 0.348
I07.1 Tricuspid insufficiency
0.000 0.658 0.342
I49.9 Cardiac arrhythmia, unspecified
0.000 0.659 0.340
I33.0 Acute and subacute infective endocarditis
0.000 0.664 0.335
I87.0 Postphlebitic syndrome
0.000 0.666 0.334
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.669 0.331
I97.1 Other functional disturbances following cardiac surgery
0.000 0.670 0.330
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.671 0.329
I80 Phlebitis and thrombophlebitis
0.000 0.672 0.328
N61 Inflammatory disorders of breast
0.326 0.674 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.675 0.325
I34.1 Mitral (valve) prolapse
0.000 0.677 0.323
N60.2 Fibroadenosis of breast
0.322 0.678 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.678 0.321
I87.9 Disorder of vein, unspecified
0.000 0.680 0.320
I51.9 Heart disease, unspecified
0.000 0.681 0.319
I20 Angina pectoris
0.000 0.687 0.313
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.691 0.309
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.694 0.306
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.694 0.305
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.696 0.304
I27.0 Primary pulmonary hypertension
0.000 0.696 0.304
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.698 0.302
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.702 0.298
I89.1 Lymphangitis
0.000 0.703 0.297
I95 Hypotension
0.000 0.708 0.292
I82.1 Thrombophlebitis migrans
0.000 0.710 0.290
I51.5 Myocardial degeneration
0.000 0.713 0.287
I49.8 Other specified cardiac arrhythmias
0.001 0.713 0.286
N60.3 Fibrosclerosis of breast
0.286 0.714 0.000
I82.0 Budd-Chiari syndrome
0.000 0.715 0.284
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.716 0.284
I51.4 Myocarditis, unspecified
0.000 0.716 0.284
N64.4 Mastodynia
0.283 0.717 0.000
I51.6 Cardiovascular disease, unspecified
0.000 0.718 0.282
I27.2 Other secondary pulmonary hypertension
0.000 0.719 0.280
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.720 0.280
I24.8 Other forms of acute ischaemic heart disease
0.000 0.721 0.279
N64.9 Disorder of breast, unspecified
0.278 0.722 0.000
N64.5 Other signs and symptoms in breast
0.274 0.725 0.000
I82.3 Embolism and thrombosis of renal vein
0.000 0.730 0.270
N64.1 Fat necrosis of breast
0.270 0.730 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.732 0.268
N64.3 Galactorrhoea not associated with childbirth
0.264 0.736 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.001 0.736 0.263
I82.2 Embolism and thrombosis of vena cava
0.000 0.737 0.263
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.741 0.259
N64.0 Fissure and fistula of nipple
0.254 0.746 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.747 0.253
N60.1 Diffuse cystic mastopathy
0.252 0.748 0.000
N64.2 Atrophy of breast
0.251 0.748 0.000
I20.0 Unstable angina
0.000 0.749 0.251
N60.4 Mammary duct ectasia
0.246 0.754 0.000
N60.8 Other benign mammary dysplasias
0.243 0.757 0.000
I95.9 Hypotension, unspecified
0.000 0.757 0.243
N60.9 Benign mammary dysplasia, unspecified
0.242 0.758 0.000
I50.0 Congestive heart failure
0.000 0.759 0.241
I89.0 Lymphoedema, not elsewhere classified
0.000 0.764 0.235
N60.0 Solitary cyst of breast
0.232 0.768 0.000
I82.8 Embolism and thrombosis of other specified veins
0.000 0.771 0.229
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.771 0.229
I51.0 Cardiac septal defect, acquired
0.000 0.776 0.224
I24.9 Acute ischaemic heart disease, unspecified
0.001 0.778 0.221
N64.8 Other specified disorders of breast
0.221 0.779 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.793 0.207
I20.1 Angina pectoris with documented spasm
0.000 0.795 0.205
I95.8 Other hypotension
0.000 0.797 0.203
I95.0 Idiopathic hypotension
0.000 0.807 0.193
I47.1 Supraventricular tachycardia
0.000 0.816 0.184
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.817 0.183
I50.1 Left ventricular failure
0.000 0.821 0.179
I51.8 Other ill-defined heart diseases
0.000 0.823 0.176
I12.0 Hypertensive renal disease with renal failure
0.000 0.859 0.141
I20.8 Other forms of angina pectoris
0.000 0.865 0.135
I34.0 Mitral (valve) insufficiency
0.000 0.867 0.133
I95.2 Hypotension due to drugs
0.000 0.868 0.131
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.887 0.113
I51.7 Cardiomegaly
0.000 0.897 0.102
I95.1 Orthostatic hypotension
0.000 0.897 0.102
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.901 0.099
I84 Haemorrhoids
0.000 0.908 0.092
I77 Other disorders of arteries and arterioles
0.000 0.911 0.089
I84.3 External thrombosed haemorrhoids
0.000 0.915 0.085
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.916 0.083
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.925 0.075
I70 Atherosclerosis
0.000 0.926 0.074
I77.6 Arteritis, unspecified
0.000 0.926 0.074
I84.0 Internal thrombosed haemorrhoids
0.000 0.928 0.072
I84.1 Internal haemorrhoids with other complications
0.000 0.929 0.071
I84.7 Unspecified thrombosed haemorrhoids
0.000 0.932 0.068
I78 Diseases of capillaries
0.000 0.932 0.067
I84.2 Internal haemorrhoids without complication
0.000 0.933 0.067
I77.8 Other specified disorders of arteries and arterioles
0.000 0.935 0.065
I71 Aortic aneurysm and dissection
0.000 0.935 0.064
I77.5 Necrosis of artery
0.000 0.936 0.064
I77.4 Coeliac artery compression syndrome
0.000 0.936 0.064
I77.3 Arterial fibromuscular dysplasia
0.000 0.936 0.064
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.937 0.063
I79.1 Aortitis in diseases classified elsewhere
0.000 0.940 0.060
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.940 0.060
I77.1 Stricture of artery
0.000 0.940 0.060
I77.2 Rupture of artery
0.000 0.940 0.059
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.941 0.059
I70.8 Atherosclerosis of other arteries
0.000 0.943 0.057
I78.8 Other diseases of capillaries
0.000 0.944 0.056
I70.9 Generalised and unspecified atherosclerosis
0.000 0.946 0.054
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.946 0.054
I77.0 Arteriovenous fistula, acquired
0.000 0.947 0.052
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.949 0.051
I84.4 External haemorrhoids with other complications
0.000 0.951 0.049
I70.1 Atherosclerosis of renal artery
0.000 0.951 0.049
I78.9 Disease of capillaries, unspecified
0.000 0.951 0.049
I72 Other aneurysm
0.000 0.952 0.047
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.953 0.046
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.953 0.046
I74 Arterial embolism and thrombosis
0.000 0.954 0.046
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.954 0.046
I70.0 Atherosclerosis of aorta
0.000 0.954 0.045
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.954 0.046
I71.0 Dissection of aorta [any part]
0.000 0.955 0.045
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.955 0.044
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.956 0.044
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.957 0.043
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.958 0.042
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.959 0.041
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.960 0.040
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.961 0.039
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.961 0.039
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.961 0.039
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.964 0.036
M13.99 Arthritis, unspecified (Site unspecified)
0.000 0.964 0.036
I72.4 Aneurysm of artery of lower extremity
0.000 0.964 0.035
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.965 0.035
I84.5 External haemorrhoids without complication
0.000 0.965 0.035
I72.9 Aneurysm of unspecified site
0.000 0.965 0.034
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.965 0.034
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.966 0.034
I72.1 Aneurysm of artery of upper extremity
0.000 0.966 0.033
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.967 0.033
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.967 0.033
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.967 0.033
I20.9 Angina pectoris, unspecified
0.000 0.967 0.033
I73 Other peripheral vascular diseases
0.000 0.968 0.031
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.969 0.031
I74.5 Embolism and thrombosis of iliac artery
0.000 0.969 0.031
I72.2 Aneurysm of renal artery
0.001 0.969 0.031
I74.8 Embolism and thrombosis of other arteries
0.000 0.969 0.031
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.969 0.030
I70.10 Atherosclerosis of renal artery (without gangrene)
0.001 0.969 0.030
I72.3 Aneurysm of iliac artery
0.001 0.971 0.029
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.971 0.029
I72.0 Aneurysm of carotid artery
0.001 0.972 0.027
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.973 0.027
I72.8 Aneurysm of other specified arteries
0.001 0.973 0.027
I78.1 Naevus, nonneoplastic
0.000 0.973 0.026

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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