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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs612260
log Bayes Factor = 9.02876
Chromosome 18   position 38,534,894  (GRCh37) Explore rs612260 on Ensembl!
Variant rs612260 is part of Cluster X0086

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
I05-I09 Chronic rheumatic heart diseases
0.998 0.002 0.000
I08 Multiple valve diseases
0.996 0.004 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.996 0.004 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.996 0.004 0.000
I49 Other cardiac arrhythmias
0.995 0.005 0.000
M15-M19 Arthrosis
0.994 0.006 0.000
Chapter I Certain infectious and parasitic diseases
0.993 0.007 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.989 0.011 0.000
Chapter X Diseases of the respiratory system
0.988 0.012 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.987 0.013 0.000
I08.0 Disorders of both mitral and aortic valves
0.986 0.014 0.000
D60-D64 Aplastic and other anaemias
0.985 0.015 0.000
C77.0 Lymph nodes of head, face and neck
0.983 0.017 0.000
M05-M14 Inflammatory polyarthropathies
0.981 0.019 0.000
M13 Other arthritis
0.979 0.021 0.000
M13.9 Arthritis, unspecified
0.978 0.022 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.971 0.029 0.000
B35-B49 Mycoses
0.971 0.029 0.000
D00-D09 In situ neoplasms
0.968 0.032 0.000
I49.3 Ventricular premature depolarisation
0.966 0.034 0.000
D64 Other anaemias
0.965 0.035 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.964 0.036 0.000
M17 Gonarthrosis [arthrosis of knee]
0.960 0.040 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.959 0.041 0.000
I51 Complications and ill-defined descriptions of heart disease
0.959 0.041 0.000
M20-M25 Other joint disorders
0.950 0.050 0.000
D64.9 Anaemia, unspecified
0.948 0.052 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.947 0.053 0.000
J00-J06 Acute upper respiratory infections
0.946 0.054 0.000
M18 Arthrosis of first carpometacarpal joint
0.942 0.058 0.000
Q60-Q64 Congenital malformations of the urinary system
0.942 0.058 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.941 0.059 0.000
M86-M90 Other osteopathies
0.938 0.062 0.000
I51.7 Cardiomegaly
0.933 0.067 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.933 0.067 0.000
B37 Candidiasis
0.932 0.068 0.000
I49.1 Atrial premature depolarisation
0.928 0.072 0.000
M24 Other specific joint derangements
0.926 0.074 0.000
I49.9 Cardiac arrhythmia, unspecified
0.918 0.082 0.000
Q61 Cystic kidney disease
0.918 0.082 0.000
D63.0 Anaemia in neoplastic disease
0.916 0.084 0.000
C77.4 Inguinal and lower limb lymph nodes
0.914 0.086 0.000
B37.0 Candidal stomatitis
0.911 0.089 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.910 0.090 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.907 0.093 0.000
J09-J18 Influenza and pneumonia
0.905 0.095 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.905 0.095 0.000
C79 Secondary malignant neoplasm of other sites
0.902 0.098 0.000
J02 Acute pharyngitis
0.901 0.099 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.899 0.101 0.000
D05 Carcinoma in situ of breast
0.898 0.102 0.000
J95-J99 Other diseases of the respiratory system
0.891 0.109 0.000
B07 Viral warts
0.891 0.109 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.889 0.111 0.000
M19 Other arthrosis
0.887 0.113 0.000
M89 Other disorders of bone
0.887 0.113 0.000
M21 Other acquired deformities of limbs
0.880 0.120 0.000
M65-M68 Disorders of synovium and tendon
0.879 0.121 0.000
M17.9 Gonarthrosis, unspecified
0.874 0.126 0.000
I44 Atrioventricular and left bundle-branch block
0.869 0.131 0.000
J02.9 Acute pharyngitis, unspecified
0.869 0.131 0.000
M13.94 Arthritis, unspecified (Hand)
0.868 0.131 0.000
B00 Herpesviral [herpes simplex] infections
0.865 0.135 0.000
C43 Malignant melanoma of skin
0.865 0.135 0.000
M17.1 Other primary gonarthrosis
0.860 0.140 0.000
Q61.3 Polycystic kidney, unspecified
0.860 0.140 0.000
I10-I15 Hypertensive diseases
0.859 0.141 0.000
C77.2 Intra-abdominal lymph nodes
0.857 0.143 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.855 0.145 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.854 0.146 0.000
B44 Aspergillosis
0.851 0.149 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.851 0.149 0.000
M19.0 Primary arthrosis of other joints
0.850 0.150 0.000
I35 Nonrheumatic aortic valve disorders
0.849 0.151 0.000
I31 Other diseases of pericardium
0.844 0.156 0.000
D50-D53 Nutritional anaemias
0.840 0.160 0.000
Q61.2 Polycystic kidney, adult type
0.839 0.161 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.839 0.161 0.000
C77.3 Axillary and upper limb lymph nodes
0.834 0.166 0.000
J18 Pneumonia, organism unspecified
0.834 0.166 0.000
D03 Melanoma in situ
0.830 0.170 0.000
M15 Polyarthrosis
0.827 0.173 0.000
M24.0 Loose body in joint
0.826 0.174 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.825 0.175 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.825 0.175 0.000
A80-A89 Viral infections of the central nervous system
0.824 0.176 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.823 0.177 0.000
I30 Acute pericarditis
0.822 0.178 0.000
J18.0 Bronchopneumonia, unspecified
0.820 0.180 0.000
C81 Hodgkin's disease
0.820 0.180 0.000
C78.0 Secondary malignant neoplasm of lung
0.819 0.181 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.807 0.193 0.000
A30-A49 Other bacterial diseases
0.806 0.194 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.804 0.196 0.000
D09 Carcinoma in situ of other and unspecified sites
0.799 0.201 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.796 0.204 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.796 0.204 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.794 0.206 0.000
I33 Acute and subacute endocarditis
0.793 0.207 0.000
I46 Cardiac arrest
0.789 0.211 0.000
M23 Internal derangement of knee
0.786 0.214 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.785 0.215 0.000
M19.04 Primary arthrosis of other joints (Hand)
0.782 0.218 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.780 0.220 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.776 0.224 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.773 0.227 0.000
B15-B19 Viral hepatitis
0.772 0.228 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.771 0.228 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.771 0.229 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.769 0.231 0.000
M24.2 Disorder of ligament
0.766 0.234 0.000
B44.1 Other pulmonary aspergillosis
0.765 0.234 0.000
I51.9 Heart disease, unspecified
0.765 0.235 0.000
M89.0 Algoneurodystrophy
0.764 0.236 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.763 0.237 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.761 0.239 0.000
I36 Nonrheumatic tricuspid valve disorders
0.760 0.240 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.759 0.240 0.000
M89.9 Disorder of bone, unspecified
0.757 0.243 0.000
M21.4 Flat foot [pes planus] (acquired)
0.756 0.244 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.755 0.245 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.754 0.246 0.000
M17.0 Primary gonarthrosis, bilateral
0.754 0.246 0.000
A15-A19 Tuberculosis
0.753 0.247 0.000
C43.4 Malignant melanoma of scalp and neck
0.751 0.249 0.000
D50 Iron deficiency anaemia
0.751 0.249 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.751 0.249 0.000
B00.9 Herpesviral infection, unspecified
0.750 0.250 0.000
I12 Hypertensive renal disease
0.749 0.251 0.000
D61 Other aplastic anaemias
0.748 0.252 0.000
J40-J47 Chronic lower respiratory diseases
0.747 0.253 0.000
I20-I25 Ischaemic heart diseases
0.745 0.255 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.743 0.257 0.000
J90-J94 Other diseases of pleura
0.743 0.257 0.000
B02 Zoster [herpes zoster]
0.742 0.258 0.000
M60-M63 Disorders of muscles
0.741 0.258 0.000
M24.6 Ankylosis of joint
0.741 0.259 0.000
M89.8 Other specified disorders of bone
0.741 0.259 0.000
M40-M43 Deforming dorsopathies
0.740 0.260 0.000
C79.6 Secondary malignant neoplasm of ovary
0.739 0.261 0.000
D64.8 Other specified anaemias
0.739 0.261 0.000
A49 Bacterial infection of unspecified site
0.739 0.261 0.000
M24.1 Other articular cartilage disorders
0.739 0.261 0.000
J06.9 Acute upper respiratory infection, unspecified
0.738 0.262 0.000
J98 Other respiratory disorders
0.736 0.264 0.000
M21.2 Flexion deformity
0.735 0.265 0.000
I49.0 Ventricular fibrillation and flutter
0.735 0.265 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.734 0.266 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.733 0.267 0.000
M80-M85 Disorders of bone density and structure
0.733 0.267 0.000
D05.0 Lobular carcinoma in situ
0.732 0.268 0.000
I07 Rheumatic tricuspid valve diseases
0.730 0.270 0.000
C81.9 Hodgkin's disease, unspecified
0.728 0.272 0.000
C43.5 Malignant melanoma of trunk
0.728 0.272 0.000
I44.0 Atrioventricular block, first degree
0.728 0.272 0.000
I44.2 Atrioventricular block, complete
0.728 0.272 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.726 0.274 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.724 0.276 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.722 0.278 0.000
M70-M79 Other soft tissue disorders
0.721 0.279 0.000
J60-J70 Lung diseases due to external agents
0.721 0.279 0.000
B35 Dermatophytosis
0.721 0.279 0.000
M67 Other disorders of synovium and tendon
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.283 0.000
I09 Other rheumatic heart diseases
0.715 0.285 0.000
I06 Rheumatic aortic valve diseases
0.715 0.285 0.000
B01 Varicella [chickenpox]
0.715 0.285 0.000
B00.1 Herpesviral vesicular dermatitis
0.715 0.285 0.000
I08.9 Multiple valve disease, unspecified
0.714 0.286 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.714 0.286 0.000
I49.2 Junctional premature depolarisation
0.714 0.286 0.000
M24.07 Loose body in joint (Ankle and foot)
0.712 0.288 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.712 0.288 0.000
B50-B64 Protozoal diseases
0.712 0.288 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.712 0.288 0.000
A75-A79 Rickettsioses
0.712 0.288 0.000
A70-A74 Other diseases caused by chlamydiae
0.712 0.288 0.000
A65-A69 Other spirochaetal diseases
0.712 0.288 0.000
A20-A28 Certain zoonotic bacterial diseases
0.712 0.288 0.000
I49.4 Other and unspecified premature depolarisation
0.711 0.289 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.711 0.289 0.000
B99-B99 Other infectious diseases
0.711 0.289 0.000
Q80-Q89 Other congenital malformations
0.710 0.290 0.000
D03.4 Melanoma in situ of scalp and neck
0.710 0.290 0.000
B37.9 Candidiasis, unspecified
0.709 0.291 0.000
M21.0 Valgus deformity, not elsewhere classified
0.707 0.292 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.707 0.293 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.706 0.293 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.706 0.293 0.000
I08.8 Other multiple valve diseases
0.705 0.295 0.000
M00-M03 Infectious arthropathies
0.705 0.295 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.705 0.295 0.000
A87 Viral meningitis
0.704 0.296 0.000
Q50-Q56 Congenital malformations of genital organs
0.703 0.296 0.000
M14 Arthropathies in other diseases classified elsewhere
0.703 0.297 0.000
M12 Other specific arthropathies
0.703 0.297 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.703 0.297 0.000
M08 Juvenile arthritis
0.703 0.297 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.702 0.298 0.000
M13.8 Other specified arthritis
0.702 0.298 0.000
M13.1 Monoarthritis, not elsewhere classified
0.702 0.298 0.000
M31 Other necrotising vasculopathies
0.701 0.298 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.701 0.298 0.000
I38 Endocarditis, valve unspecified
0.700 0.300 0.000
M66 Spontaneous rupture of synovium and tendon
0.700 0.300 0.000
M30 Polyarteritis nodosa and related conditions
0.700 0.300 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.699 0.301 0.000
I37 Pulmonary valve disorders
0.698 0.302 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.698 0.302 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.696 0.303 0.000
Q35-Q37 Cleft lip and cleft palate
0.696 0.303 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.696 0.303 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.696 0.303 0.000
B48 Other mycoses, not elsewhere classified
0.696 0.304 0.000
B47 Mycetoma
0.696 0.304 0.000
B46 Zygomycosis
0.696 0.304 0.000
B45 Cryptococcosis
0.696 0.304 0.000
B43 Chromomycosis and phaeomycotic abscess
0.696 0.304 0.000
B42 Sporotrichosis
0.696 0.304 0.000
B41 Paracoccidioidomycosis
0.696 0.304 0.000
B40 Blastomycosis
0.696 0.304 0.000
B39 Histoplasmosis
0.696 0.304 0.000
B38 Coccidioidomycosis
0.696 0.304 0.000
B36 Other superficial mycoses
0.696 0.304 0.000
B49 Unspecified mycosis
0.696 0.304 0.000
I30.9 Acute pericarditis, unspecified
0.695 0.305 0.000
M34 Systemic sclerosis
0.695 0.305 0.000
O80-O84 Delivery
0.694 0.306 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.694 0.306 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.694 0.306 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.694 0.306 0.000
I44.6 Other and unspecified fascicular block
0.694 0.306 0.000
I31.9 Disease of pericardium, unspecified
0.694 0.306 0.000
C77.1 Intrathoracic lymph nodes
0.693 0.307 0.000
M65 Synovitis and tenosynovitis
0.693 0.307 0.000
J17 Pneumonia in diseases classified elsewhere
0.693 0.307 0.000
M87 Osteonecrosis
0.692 0.307 0.000
M90 Osteopathies in diseases classified elsewhere
0.692 0.308 0.000
D64.4 Congenital dyserythropoietic anaemia
0.692 0.308 0.000
D64.3 Other sideroblastic anaemias
0.692 0.308 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.692 0.308 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.692 0.308 0.000
D64.0 Hereditary sideroblastic anaemia
0.692 0.308 0.000
B06 Rubella [German measles]
0.691 0.309 0.000
B05 Measles
0.691 0.309 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.691 0.309 0.000
B04 Monkeypox
0.691 0.309 0.000
B03 Smallpox
0.691 0.309 0.000
D07.5 Prostate
0.691 0.309 0.000
D55-D59 Haemolytic anaemias
0.690 0.310 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.689 0.310 0.000
M35 Other systemic involvement of connective tissue
0.690 0.310 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.689 0.310 0.000
I05 Rheumatic mitral valve diseases
0.689 0.311 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.688 0.312 0.000
M17.5 Other secondary gonarthrosis
0.688 0.312 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.688 0.312 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.688 0.312 0.000
I51.6 Cardiovascular disease, unspecified
0.688 0.312 0.000
I51.5 Myocardial degeneration
0.688 0.312 0.000
I51.4 Myocarditis, unspecified
0.688 0.312 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.688 0.312 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.688 0.312 0.000
I51.0 Cardiac septal defect, acquired
0.688 0.312 0.000
C91 Lymphoid leukaemia
0.688 0.312 0.000
B65-B83 Helminthiases
0.688 0.312 0.000
I49.8 Other specified cardiac arrhythmias
0.688 0.312 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.687 0.313 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.686 0.314 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.685 0.315 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.684 0.316 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.681 0.319 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.681 0.319 0.000
M33 Dermatopolymyositis
0.681 0.319 0.000
M32 Systemic lupus erythematosus
0.681 0.319 0.000
M13.0 Polyarthritis, unspecified
0.680 0.320 0.000
B25-B34 Other viral diseases
0.680 0.320 0.000
I15 Secondary hypertension
0.680 0.320 0.000
M24.02 Loose body in joint (Upper arm)
0.680 0.320 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.680 0.320 0.000
D63.1 Anaemia in other chronic diseases classified elsewhere
0.679 0.321 0.000
J14 Pneumonia due to Haemophilus influenzae
0.679 0.321 0.000
D09.0 Bladder
0.678 0.322 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.678 0.322 0.000
C88 Malignant immunoproliferative diseases
0.677 0.322 0.000
M19.03 Primary arthrosis of other joints (Forearm)
0.677 0.323 0.000
J91 Pleural effusion in conditions classified elsewhere
0.677 0.323 0.000
Q00-Q07 Congenital malformations of the nervous system
0.676 0.324 0.000
M89.04 Algoneurodystrophy (Hand)
0.676 0.324 0.000
I35.9 Aortic valve disorder, unspecified
0.676 0.324 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.675 0.325 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.675 0.325 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.675 0.325 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.675 0.325 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.675 0.325 0.000
Q64 Other congenital malformations of urinary system
0.675 0.325 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.675 0.325 0.000
M17.3 Other posttraumatic gonarthrosis
0.675 0.325 0.000
M21.1 Varus deformity, not elsewhere classified
0.675 0.325 0.000
I25 Chronic ischaemic heart disease
0.675 0.325 0.000
M23.5 Chronic instability of knee
0.674 0.326 0.000
D50.8 Other iron deficiency anaemias
0.673 0.327 0.000
M88 Paget's disease of bone [osteitis deformans]
0.672 0.327 0.000
M86 Osteomyelitis
0.672 0.328 0.000
M91-M94 Chondropathies
0.671 0.328 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.671 0.329 0.000
M45-M49 Spondylopathies
0.670 0.330 0.000
A49.0 Staphylococcal infection, unspecified
0.670 0.330 0.000
D62 Acute posthaemorrhagic anaemia
0.669 0.330 0.000
B37.7 Candidal septicaemia
0.668 0.332 0.000
B37.6 Candidal endocarditis
0.668 0.332 0.000
B37.5 Candidal meningitis
0.668 0.332 0.000
B37.4 Candidiasis of other urogenital sites
0.668 0.332 0.000
B37.2 Candidiasis of skin and nail
0.668 0.332 0.000
B37.1 Pulmonary candidiasis
0.668 0.332 0.000
I46.9 Cardiac arrest, unspecified
0.668 0.332 0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot
0.668 0.332 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.666 0.334 0.000
J86 Pyothorax
0.666 0.334 0.000
I31.3 Pericardial effusion (noninflammatory)
0.665 0.335 0.000
I22 Subsequent myocardial infarction
0.665 0.335 0.000
M24.9 Joint derangement, unspecified
0.664 0.336 0.000
M24.7 Protrusio acetabuli
0.664 0.336 0.000
M24.5 Contracture of joint
0.664 0.336 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.664 0.336 0.000
J03 Acute tonsillitis
0.664 0.336 0.000
C77.8 Lymph nodes of multiple regions
0.663 0.337 0.000
M10 Gout
0.663 0.337 0.000
Q61.9 Cystic kidney disease, unspecified
0.658 0.342 0.000
Q61.8 Other cystic kidney diseases
0.658 0.342 0.000
Q61.5 Medullary cystic kidney
0.658 0.342 0.000
Q61.4 Renal dysplasia
0.658 0.342 0.000
Q61.1 Polycystic kidney, infantile type
0.658 0.342 0.000
Q61.0 Congenital single renal cyst
0.658 0.342 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.658 0.342 0.000
C81.1 Nodular sclerosis
0.657 0.342 0.000
J98.1 Pulmonary collapse
0.657 0.343 0.000
J01 Acute sinusitis
0.657 0.343 0.000
J99.8 Respiratory disorders in other diseases classified elsewhere
0.657 0.343 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.656 0.344 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.656 0.344 0.000
J04 Acute laryngitis and tracheitis
0.654 0.345 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.653 0.347 0.000
M13.98 Arthritis, unspecified (Other)
0.653 0.347 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.652 0.348 0.000
C95 Leukaemia of unspecified cell type
0.652 0.348 0.000
C94 Other leukaemias of specified cell type
0.652 0.348 0.000
C93 Monocytic leukaemia
0.652 0.348 0.000
C86 Other specified types of T/NK-cell lymphoma
0.652 0.348 0.000
C15-C26 Malignant neoplasms of digestive organs
0.652 0.348 0.000
I44.1 Atrioventricular block, second degree
0.651 0.349 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.649 0.351 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.649 0.351 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.649 0.351 0.000
J12 Viral pneumonia, not elsewhere classified
0.649 0.351 0.000
J09 Influenza due to certain identified influenza virus
0.649 0.351 0.000
M13.93 Arthritis, unspecified (Forearm)
0.648 0.352 0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)
0.647 0.353 0.000
J85 Abscess of lung and mediastinum
0.647 0.353 0.000
J02.8 Acute pharyngitis due to other specified organisms
0.646 0.354 0.000
J02.0 Streptococcal pharyngitis
0.646 0.354 0.000
I11 Hypertensive heart disease
0.646 0.354 0.000
Q21 Congenital malformations of cardiac septa
0.646 0.354 0.000
I33.0 Acute and subacute infective endocarditis
0.645 0.355 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.644 0.356 0.000
D05.7 Other carcinoma in situ of breast
0.644 0.356 0.000
I42 Cardiomyopathy
0.642 0.358 0.000
D03.5 Melanoma in situ of trunk
0.641 0.359 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.641 0.359 0.000
C79.2 Secondary malignant neoplasm of skin
0.640 0.359 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.640 0.360 0.000
J96 Respiratory failure, not elsewhere classified
0.639 0.361 0.000
M15.1 Heberden's nodes (with arthropathy)
0.639 0.361 0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.638 0.362 0.000
I60-I69 Cerebrovascular diseases
0.637 0.363 0.000
Q27 Other congenital malformations of peripheral vascular system
0.637 0.363 0.000
O24 Diabetes mellitus in pregnancy
0.637 0.363 0.000
I12.0 Hypertensive renal disease with renal failure
0.637 0.363 0.000
M11 Other crystal arthropathies
0.636 0.363 0.000
M19.8 Other specified arthrosis
0.636 0.364 0.000
M19.2 Other secondary arthrosis
0.636 0.364 0.000
M89.6 Osteopathy after poliomyelitis
0.636 0.364 0.000
M89.5 Osteolysis
0.636 0.364 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.636 0.364 0.000
M89.3 Hypertrophy of bone
0.636 0.364 0.000
M89.2 Other disorders of bone development and growth
0.636 0.364 0.000
M89.1 Epiphyseal arrest
0.636 0.364 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.635 0.364 0.000
D50.9 Iron deficiency anaemia, unspecified
0.635 0.365 0.000
J10 Influenza due to identified influenza virus
0.635 0.365 0.000
I35.8 Other aortic valve disorders
0.634 0.366 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.631 0.369 0.000
M21.9 Acquired deformity of limb, unspecified
0.631 0.369 0.000
M21.8 Other specified acquired deformities of limbs
0.631 0.369 0.000
M21.7 Unequal limb length (acquired)
0.631 0.369 0.000
M21.6 Other acquired deformities of ankle and foot
0.631 0.369 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.630 0.370 0.000
B37.8 Candidiasis of other sites
0.628 0.372 0.000
J11 Influenza, virus not identified
0.627 0.372 0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.627 0.373 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.627 0.373 0.000
M23.8 Other internal derangements of knee
0.625 0.375 0.000
M24.26 Disorder of ligament (Lower leg)
0.625 0.375 0.000
Q60.2 Renal agenesis, unspecified
0.624 0.376 0.000
I44.5 Left posterior fascicular block
0.623 0.377 0.000
I44.4 Left anterior fascicular block
0.623 0.377 0.000
O00-O08 Pregnancy with abortive outcome
0.622 0.378 0.000
A40 Streptococcal septicaemia
0.621 0.379 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.621 0.379 0.000
B00.8 Other forms of herpesviral infection
0.620 0.379 0.000
B00.7 Disseminated herpesviral disease
0.620 0.379 0.000
B00.5 Herpesviral ocular disease
0.620 0.379 0.000
B00.4 Herpesviral encephalitis
0.620 0.379 0.000
B00.3 Herpesviral meningitis
0.620 0.379 0.000
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis
0.620 0.379 0.000
B00.0 Eczema herpeticum
0.620 0.379 0.000
C43.8 Overlapping malignant melanoma of skin
0.620 0.379 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.620 0.379 0.000
C43.0 Malignant melanoma of lip
0.620 0.379 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.618 0.382 0.000
J46 Status asthmaticus
0.617 0.383 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.617 0.383 0.000
A87.9 Viral meningitis, unspecified
0.617 0.383 0.000
D04 Carcinoma in situ of skin
0.617 0.383 0.000
Chapter VII Diseases of the eye and adnexa
0.617 0.383 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.616 0.384 0.000
I13 Hypertensive heart and renal disease
0.616 0.384 0.000
J44 Other chronic obstructive pulmonary disease
0.615 0.385 0.000
O20 Haemorrhage in early pregnancy
0.614 0.386 0.000
C43.9 Malignant melanoma of skin, unspecified
0.614 0.386 0.000
B18 Chronic viral hepatitis
0.614 0.386 0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.614 0.386 0.000
M19.02 Primary arthrosis of other joints (Upper arm)
0.613 0.387 0.000
M77 Other enthesopathies
0.612 0.388 0.000
J81 Pulmonary oedema
0.611 0.389 0.000
B44.9 Aspergillosis, unspecified
0.610 0.389 0.000
B44.8 Other forms of aspergillosis
0.610 0.389 0.000
B44.7 Disseminated aspergillosis
0.610 0.389 0.000
B44.2 Tonsillar aspergillosis
0.610 0.389 0.000
B44.0 Invasive pulmonary aspergillosis
0.610 0.389 0.000
Chapter XX External causes of morbidity and mortality
0.610 0.390 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.609 0.390 0.000
M19.08 Primary arthrosis of other joints (Other)
0.609 0.391 0.000
M19.06 Primary arthrosis of other joints-Lower leg
0.609 0.391 0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)
0.609 0.391 0.000
M19.00 Primary arthrosis of other joints (Multiple sites)
0.609 0.391 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.609 0.391 0.000
M21.26 Flexion deformity (Lower leg)
0.609 0.391 0.000
M24.67 Ankylosis of joint (Ankle and foot)
0.609 0.391 0.000
Q63 Other congenital malformations of kidney
0.608 0.391 0.000
I31.8 Other specified diseases of pericardium
0.605 0.395 0.000
I31.2 Haemopericardium, not elsewhere classified
0.605 0.395 0.000
I31.1 Chronic constrictive pericarditis
0.605 0.395 0.000
I31.0 Chronic adhesive pericarditis
0.605 0.395 0.000
D80-D89 Certain disorders involving the immune mechanism
0.603 0.397 0.000
D53 Other nutritional anaemias
0.602 0.397 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.602 0.398 0.000
B02.9 Zoster without complication
0.602 0.398 0.000
I34 Nonrheumatic mitral valve disorders
0.600 0.400 0.000
O85-O92 Complications predominantly related to the puerperium
0.600 0.400 0.000
I12.9 Hypertensive renal disease without renal failure
0.599 0.401 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.598 0.402 0.000
J18.8 Other pneumonia, organism unspecified
0.598 0.402 0.000
J18.2 Hypostatic pneumonia, unspecified
0.598 0.402 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.597 0.402 0.000
J92 Pleural plaque
0.597 0.403 0.000
M67.8 Other specified disorders of synovium and tendon
0.597 0.403 0.000
M89.87 Other specified disorders of bone (Ankle and foot)
0.597 0.403 0.000
M21.3 Wrist or foot drop (acquired)
0.596 0.404 0.000
M75 Shoulder lesions
0.595 0.405 0.000
D03.9 Melanoma in situ, unspecified
0.595 0.405 0.000
D03.8 Melanoma in situ of other sites
0.595 0.405 0.000
D03.2 Melanoma in situ of ear and external auricular canal
0.595 0.405 0.000
D03.1 Melanoma in situ of eyelid, including canthus
0.595 0.405 0.000
D03.0 Melanoma in situ of lip
0.595 0.405 0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.594 0.406 0.000
M19.09 Primary arthrosis of other joints (Site unspecified)
0.593 0.407 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.593 0.407 0.000
M15.9 Polyarthrosis, unspecified
0.593 0.407 0.000
M15.0 Primary generalised (osteo)arthrosis
0.593 0.407 0.000
M15.8 Other polyarthrosis
0.593 0.407 0.000
M15.4 Erosive (osteo)arthrosis
0.593 0.407 0.000
M15.3 Secondary multiple arthrosis
0.593 0.407 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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