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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs113173951
log Bayes Factor = 6.15041
Chromosome 1   position 27,877,418  (GRCh37) Explore rs113173951 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.002 0.998
I30-I52 Other forms of heart disease
0.000 0.002 0.998
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.005 0.995
I73 Other peripheral vascular diseases
0.000 0.020 0.980
I21 Acute myocardial infarction
0.000 0.028 0.972
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.036 0.964
I05-I09 Chronic rheumatic heart diseases
0.000 0.043 0.957
I73.0 Raynaud's syndrome
0.000 0.045 0.955
I10-I15 Hypertensive diseases
0.000 0.049 0.951
I44 Atrioventricular and left bundle-branch block
0.000 0.063 0.937
I47 Paroxysmal tachycardia
0.000 0.065 0.935
I25.2 Old myocardial infarction
0.000 0.072 0.928
I24 Other acute ischaemic heart diseases
0.000 0.089 0.911
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.091 0.909
I47.2 Ventricular tachycardia
0.000 0.092 0.908
I51 Complications and ill-defined descriptions of heart disease
0.000 0.094 0.906
I77 Other disorders of arteries and arterioles
0.000 0.105 0.895
I05 Rheumatic mitral valve diseases
0.000 0.110 0.890
I72 Other aneurysm
0.000 0.110 0.890
I08 Multiple valve diseases
0.000 0.120 0.880
I21.9 Acute myocardial infarction, unspecified
0.000 0.123 0.877
I24.8 Other forms of acute ischaemic heart disease
0.000 0.127 0.873
I10 Essential (primary) hypertension
0.000 0.130 0.870
I49 Other cardiac arrhythmias
0.000 0.130 0.870
I77.1 Stricture of artery
0.000 0.136 0.864
I25.5 Ischaemic cardiomyopathy
0.000 0.141 0.859
I50 Heart failure
0.000 0.146 0.854
I44.0 Atrioventricular block, first degree
0.000 0.150 0.850
I73.9 Peripheral vascular disease, unspecified
0.000 0.151 0.849
I51.9 Heart disease, unspecified
0.000 0.172 0.828
I15 Secondary hypertension
0.000 0.175 0.825
I45 Other conduction disorders
0.000 0.177 0.823
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.180 0.820
I21.4 Acute subendocardial myocardial infarction
0.000 0.180 0.820
I46 Cardiac arrest
0.000 0.180 0.820
I72.4 Aneurysm of artery of lower extremity
0.000 0.183 0.817
I11 Hypertensive heart disease
0.000 0.187 0.813
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.195 0.805
I70 Atherosclerosis
0.000 0.198 0.802
I44.2 Atrioventricular block, complete
0.000 0.200 0.800
I42 Cardiomyopathy
0.000 0.200 0.800
I22 Subsequent myocardial infarction
0.000 0.202 0.798
I49.8 Other specified cardiac arrhythmias
0.000 0.203 0.797
I25.3 Aneurysm of heart
0.000 0.204 0.796
I44.1 Atrioventricular block, second degree
0.000 0.208 0.792
I37 Pulmonary valve disorders
0.000 0.209 0.791
I51.8 Other ill-defined heart diseases
0.000 0.213 0.787
I34 Nonrheumatic mitral valve disorders
0.000 0.217 0.783
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.218 0.782
I49.3 Ventricular premature depolarisation
0.000 0.226 0.774
I50.0 Congestive heart failure
0.000 0.231 0.769
I36 Nonrheumatic tricuspid valve disorders
0.000 0.240 0.760
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.241 0.759
I05.0 Mitral stenosis
0.000 0.242 0.758
I42.0 Dilated cardiomyopathy
0.000 0.244 0.756
I30 Acute pericarditis
0.000 0.255 0.744
I08.0 Disorders of both mitral and aortic valves
0.000 0.260 0.740
I49.0 Ventricular fibrillation and flutter
0.000 0.262 0.738
I15.1 Hypertension secondary to other renal disorders
0.000 0.265 0.735
I44.6 Other and unspecified fascicular block
0.000 0.268 0.732
I46.0 Cardiac arrest with successful resuscitation
0.000 0.268 0.732
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.269 0.731
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.277 0.723
I73.8 Other specified peripheral vascular diseases
0.000 0.277 0.723
I05.2 Mitral stenosis with insufficiency
0.000 0.282 0.718
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
I52 Other heart disorders in diseases classified elsewhere
0.000 0.284 0.716
I48 Atrial fibrillation and flutter
0.000 0.284 0.716
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.284 0.716
I41 Myocarditis in diseases classified elsewhere
0.000 0.284 0.716
I40 Acute myocarditis
0.000 0.284 0.716
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.284 0.716
I32 Pericarditis in diseases classified elsewhere
0.000 0.284 0.716
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.286 0.714
I23 Certain current complications following acute myocardial infarction
0.000 0.288 0.712
I05.1 Rheumatic mitral insufficiency
0.000 0.292 0.708
I05.9 Mitral valve disease, unspecified
0.000 0.293 0.707
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.297 0.702
I74 Arterial embolism and thrombosis
0.000 0.298 0.702
I72.0 Aneurysm of carotid artery
0.000 0.300 0.700
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.303 0.697
I44.3 Other and unspecified atrioventricular block
0.000 0.303 0.697
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.304 0.696
I09 Other rheumatic heart diseases
0.000 0.314 0.686
I06 Rheumatic aortic valve diseases
0.000 0.314 0.686
I47.1 Supraventricular tachycardia
0.000 0.317 0.683
I13 Hypertensive heart and renal disease
0.000 0.318 0.682
I31 Other diseases of pericardium
0.000 0.320 0.680
I49.4 Other and unspecified premature depolarisation
0.000 0.320 0.680
I44.5 Left posterior fascicular block
0.000 0.328 0.672
I44.4 Left anterior fascicular block
0.000 0.328 0.672
I45.1 Other and unspecified right bundle-branch block
0.000 0.331 0.669
I45.9 Conduction disorder, unspecified
0.000 0.334 0.666
I24.1 Dressler's syndrome
0.000 0.347 0.653
I50.9 Heart failure, unspecified
0.000 0.347 0.653
I51.0 Cardiac septal defect, acquired
0.000 0.348 0.651
I51.5 Myocardial degeneration
0.000 0.350 0.650
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.350 0.650
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.350 0.650
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.350 0.650
I45.5 Other specified heart block
0.000 0.352 0.648
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.358 0.642
I37.1 Pulmonary valve insufficiency
0.000 0.358 0.642
I77.5 Necrosis of artery
0.000 0.359 0.641
I77.4 Coeliac artery compression syndrome
0.000 0.359 0.641
I77.3 Arterial fibromuscular dysplasia
0.000 0.359 0.641
I77.2 Rupture of artery
0.000 0.359 0.641
I20 Angina pectoris
0.000 0.360 0.640
I05.8 Other mitral valve diseases
0.000 0.361 0.638
I72.9 Aneurysm of unspecified site
0.000 0.362 0.638
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.362 0.638
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.362 0.638
I72.2 Aneurysm of renal artery
0.000 0.362 0.638
I72.1 Aneurysm of artery of upper extremity
0.000 0.362 0.638
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.363 0.637
I22.8 Subsequent myocardial infarction of other sites
0.000 0.368 0.632
I08.9 Multiple valve disease, unspecified
0.000 0.369 0.631
I51.4 Myocarditis, unspecified
0.000 0.370 0.630
I49.2 Junctional premature depolarisation
0.000 0.376 0.624
I47.0 Reentry ventricular arrhythmia
0.000 0.378 0.622
I45.2 Bifascicular block
0.000 0.378 0.622
E78.0 Pure hypercholesterolaemia
0.000 0.379 0.621
I42.6 Alcoholic cardiomyopathy
0.000 0.380 0.620
I70.0 Atherosclerosis of aorta
0.000 0.395 0.605
I51.6 Cardiovascular disease, unspecified
0.000 0.398 0.602
I25.4 Coronary artery aneurysm
0.000 0.398 0.602
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.399 0.601
I72.8 Aneurysm of other specified arteries
0.000 0.401 0.598
I72.3 Aneurysm of iliac artery
0.000 0.402 0.598
I30.9 Acute pericarditis, unspecified
0.000 0.405 0.595
I33 Acute and subacute endocarditis
0.000 0.407 0.593
I15.9 Seconday hypertension, unspecified
0.000 0.408 0.591
I15.8 Other secondary hypertension
0.000 0.408 0.591
I15.2 Hypertension secondary to endocrine disorders
0.000 0.408 0.591
I15.0 Renovascular hypertension
0.000 0.408 0.591
I45.4 Nonspecific intraventricular block
0.000 0.410 0.590
I45.0 Right fascicular block
0.000 0.410 0.590
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.411 0.588
I46.1 Sudden cardiac death, so described
0.000 0.412 0.588
I49.1 Atrial premature depolarisation
0.000 0.416 0.584
I78 Diseases of capillaries
0.000 0.419 0.581
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.419 0.581
I20.0 Unstable angina
0.000 0.423 0.577
I70.9 Generalised and unspecified atherosclerosis
0.000 0.425 0.575
I70.8 Atherosclerosis of other arteries
0.000 0.425 0.575
I70.1 Atherosclerosis of renal artery
0.000 0.425 0.575
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.426 0.574
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.426 0.574
I42.5 Other restrictive cardiomyopathy
0.000 0.426 0.574
I42.4 Endocardial fibroelastosis
0.000 0.426 0.574
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.426 0.574
I77.8 Other specified disorders of arteries and arterioles
0.000 0.427 0.573
E78.5 Hyperlipidaemia, unspecified
0.000 0.428 0.572
I45.8 Other specified conduction disorders
0.000 0.431 0.569
I34.0 Mitral (valve) insufficiency
0.000 0.431 0.569
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.432 0.568
I08.8 Other multiple valve diseases
0.000 0.433 0.567
I37.9 Pulmonary valve disorder, unspecified
0.000 0.433 0.567
I37.8 Other pulmonary valve disorders
0.000 0.433 0.567
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.433 0.567
I37.0 Pulmonary valve stenosis
0.000 0.433 0.567
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.439 0.561
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.439 0.561
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.441 0.558
I45.3 Trifascicular block
0.000 0.443 0.557
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.455 0.545
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.455 0.545
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.455 0.545
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.455 0.545
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.455 0.544
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.458 0.542
I51.7 Cardiomegaly
0.000 0.458 0.542
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.459 0.541
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.459 0.541
I34.1 Mitral (valve) prolapse
0.000 0.460 0.540
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.463 0.537
I30.8 Other forms of acute pericarditis
0.000 0.466 0.534
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.466 0.534
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.470 0.530
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.472 0.528
I31.9 Disease of pericardium, unspecified
0.000 0.473 0.527
I07 Rheumatic tricuspid valve diseases
0.000 0.474 0.526
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.476 0.524
I79.1 Aortitis in diseases classified elsewhere
0.000 0.476 0.524
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.476 0.524
E78.2 Mixed hyperlipidaemia
0.000 0.478 0.522
I71 Aortic aneurysm and dissection
0.000 0.483 0.517
I02 Rheumatic chorea
0.000 0.486 0.514
I01 Rheumatic fever with heart involvement
0.000 0.486 0.514
I00 Rheumatic fever without mention of heart involvement
0.000 0.486 0.514
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.487 0.513
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.487 0.513
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.487 0.513
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.487 0.513
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.487 0.513
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.487 0.513
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.487 0.513
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.487 0.513
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.487 0.513
I40.9 Acute myocarditis, unspecified
0.000 0.487 0.513
I40.8 Other acute myocarditis
0.000 0.487 0.513
I40.1 Isolated myocarditis
0.000 0.487 0.513
I40.0 Infective myocarditis
0.000 0.487 0.513
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.487 0.513
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.487 0.513
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.487 0.513
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.487 0.513
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.487 0.513
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.487 0.513
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.487 0.513
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.487 0.513
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.487 0.513
I48.4 Atypical atrial flutter
0.000 0.487 0.513
I48.3 Typical atrial flutter
0.000 0.487 0.513
I48.2 Chronic atrial fibrillation
0.000 0.487 0.513
I48.1 Persistent atrial fibrillation
0.000 0.487 0.513
I48.0 Paroxysmal atrial fibrillation
0.000 0.487 0.513
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.487 0.513
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.487 0.513
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.487 0.513
I74.8 Embolism and thrombosis of other arteries
0.000 0.489 0.511
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.489 0.511
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.489 0.511
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.489 0.511
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.489 0.511
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.489 0.511
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.489 0.511
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.489 0.511
I23.8 Other current complications following acute myocardial infarction
0.000 0.494 0.506
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.497 0.503
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.497 0.503
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.497 0.503
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.497 0.503
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.498 0.502
I50.1 Left ventricular failure
0.000 0.500 0.500
I77.6 Arteritis, unspecified
0.000 0.504 0.496
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.508 0.492
I06.8 Other rheumatic aortic valve diseases
0.000 0.508 0.492
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.508 0.492
I06.1 Rheumatic aortic insufficiency
0.000 0.508 0.492
I06.0 Rheumatic aortic stenosis
0.000 0.508 0.492
I09.9 Rheumatic heart disease, unspecified
0.000 0.508 0.492
I09.8 Other specified rheumatic heart diseases
0.000 0.508 0.492
I09.2 Chronic rheumatic pericarditis
0.000 0.508 0.492
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.508 0.492
I09.0 Rheumatic myocarditis
0.000 0.508 0.492
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.511 0.489
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.511 0.489
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.511 0.489
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.511 0.489
I30.1 Infective pericarditis
0.000 0.511 0.489
I31.8 Other specified diseases of pericardium
0.000 0.512 0.488
I31.2 Haemopericardium, not elsewhere classified
0.000 0.512 0.488
I31.1 Chronic constrictive pericarditis
0.000 0.512 0.488
I31.0 Chronic adhesive pericarditis
0.000 0.512 0.488
I46.9 Cardiac arrest, unspecified
0.000 0.512 0.487
I74.5 Embolism and thrombosis of iliac artery
0.000 0.513 0.487
E78.4 Other hyperlipidaemia
0.000 0.522 0.478
I45.6 Preexcitation syndrome
0.000 0.526 0.474
I77.0 Arteriovenous fistula, acquired
0.000 0.530 0.470
I12 Hypertensive renal disease
0.000 0.536 0.464
I42.8 Other cardiomyopathies
0.000 0.536 0.464
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.536 0.463
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.538 0.462
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.539 0.460
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.552 0.448
I42.2 Other hypertrophic cardiomyopathy
0.000 0.555 0.445
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.559 0.441
I20.1 Angina pectoris with documented spasm
0.000 0.566 0.434
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.566 0.434
E78.6 Lipoprotein deficiency
0.000 0.569 0.431
E78.3 Hyperchylomicronaemia
0.000 0.569 0.431
I33.9 Acute endocarditis, unspecified
0.000 0.575 0.425
E78.8 Other disorders of lipoprotein metabolism
0.000 0.583 0.417
I78.9 Disease of capillaries, unspecified
0.000 0.583 0.417
I42.9 Cardiomyopathy, unspecified
0.000 0.587 0.413
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.588 0.412
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.588 0.412
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.588 0.412
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.588 0.412
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.588 0.412
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.588 0.412
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.588 0.412
E78.1 Pure hyperglyceridaemia
0.000 0.589 0.411
I78.8 Other diseases of capillaries
0.000 0.596 0.404
I38 Endocarditis, valve unspecified
0.000 0.601 0.399
I31.3 Pericardial effusion (noninflammatory)
0.000 0.605 0.395
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.606 0.394
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.609 0.391
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.618 0.382
I07.9 Tricuspid valve disease, unspecified
0.000 0.622 0.377
I07.8 Other tricuspid valve diseases
0.000 0.622 0.377
I07.2 Tricuspid stenosis with insufficiency
0.000 0.622 0.377
I07.0 Tricuspid stenosis
0.000 0.622 0.377
I71.0 Dissection of aorta [any part]
0.000 0.623 0.377
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.628 0.372
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.629 0.371
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.629 0.371
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.629 0.371
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.629 0.371
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.631 0.369
I01.8 Other acute rheumatic heart disease
0.000 0.631 0.369
I01.2 Acute rheumatic myocarditis
0.000 0.631 0.369
I01.1 Acute rheumatic endocarditis
0.000 0.631 0.369
I01.0 Acute rheumatic pericarditis
0.000 0.631 0.369
I02.9 Rheumatic chorea without heart involvement
0.000 0.631 0.369
I02.0 Rheumatic chorea with heart involvement
0.000 0.631 0.369
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.656 0.344
I20.8 Other forms of angina pectoris
0.000 0.676 0.324
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.684 0.316
I49.5 Sick sinus syndrome
0.000 0.688 0.312
I33.0 Acute and subacute infective endocarditis
0.000 0.698 0.302
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.706 0.294
I97.1 Other functional disturbances following cardiac surgery
0.000 0.709 0.290
I12.9 Hypertensive renal disease without renal failure
0.000 0.717 0.283
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.717 0.283
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.719 0.281
I97.0 Postcardiotomy syndrome
0.000 0.719 0.281
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.721 0.279
I20.9 Angina pectoris, unspecified
0.000 0.730 0.270
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.733 0.267
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.733 0.267
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.733 0.267
I98.0 Cardiovascular syphilis
0.000 0.733 0.267
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.736 0.264
I44.7 Left bundle-branch block, unspecified
0.000 0.742 0.258
I99 Other and unspecified disorders of circulatory system
0.000 0.750 0.250
I60-I69 Cerebrovascular diseases
0.000 0.753 0.247
I28 Other diseases of pulmonary vessels
0.000 0.754 0.246
I35 Nonrheumatic aortic valve disorders
0.000 0.754 0.246
I78.1 Naevus, nonneoplastic
0.000 0.758 0.242
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.773 0.227
I65.2 Occlusion and stenosis of carotid artery
0.000 0.780 0.220
I95 Hypotension
0.000 0.782 0.218
I07.1 Tricuspid insufficiency
0.001 0.783 0.217
I12.0 Hypertensive renal disease with renal failure
0.000 0.789 0.211
I08.1 Disorders of both mitral and tricuspid valves
0.001 0.801 0.199
I26 Pulmonary embolism
0.000 0.804 0.196
I35.8 Other aortic valve disorders
0.000 0.813 0.187
R60.0 Localised oedema
0.000 0.820 0.180
I69 Sequelae of cerebrovascular disease
0.000 0.820 0.180
I27 Other pulmonary heart diseases
0.000 0.821 0.179
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.823 0.177
I67 Other cerebrovascular diseases
0.000 0.823 0.177
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.823 0.176
I28.1 Aneurysm of pulmonary artery
0.000 0.823 0.176
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.823 0.176
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.829 0.171
I95.8 Other hypotension
0.000 0.832 0.168
I69.3 Sequelae of cerebral infarction
0.000 0.835 0.165
I95.9 Hypotension, unspecified
0.000 0.836 0.164
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.837 0.163
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.837 0.163
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.837 0.163
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.837 0.163
I67.9 Cerebrovascular disease, unspecified
0.000 0.844 0.156
I95.1 Orthostatic hypotension
0.000 0.851 0.149
I28.8 Other specified diseases of pulmonary vessels
0.001 0.851 0.148
I60 Subarachnoid haemorrhage
0.000 0.852 0.148
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.852 0.148
I49.9 Cardiac arrhythmia, unspecified
0.001 0.853 0.146
I62 Other nontraumatic intracranial haemorrhage
0.000 0.855 0.145
I67.2 Cerebral atherosclerosis
0.000 0.860 0.140
I35.9 Aortic valve disorder, unspecified
0.000 0.865 0.134
I65.1 Occlusion and stenosis of basilar artery
0.000 0.868 0.131
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.871 0.129
I27.1 Kyphoscoliotic heart disease
0.000 0.871 0.128
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.873 0.127
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.873 0.127
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.873 0.127
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.873 0.127
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.873 0.127
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.873 0.127
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.873 0.127
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.873 0.127
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.873 0.127
I67.5 Moyamoya disease
0.000 0.873 0.127
I67.4 Hypertensive encephalopathy
0.000 0.873 0.127
I67.3 Progressive vascular leukoencephalopathy
0.000 0.873 0.127
I67.1 Cerebral aneurysm, nonruptured
0.000 0.874 0.126
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.875 0.125
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.878 0.122
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.879 0.121
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.883 0.117
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.883 0.117
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.883 0.117
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.884 0.116
I27.0 Primary pulmonary hypertension
0.000 0.884 0.116
I27.8 Other specified pulmonary heart diseases
0.000 0.885 0.115
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.885 0.115
I63 Cerebral infarction
0.000 0.886 0.114
I27.9 Pulmonary heart disease, unspecified
0.000 0.888 0.111
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.888 0.111
I27.2 Other secondary pulmonary hypertension
0.000 0.890 0.110
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.892 0.108
I60.8 Other subarachnoid haemorrhage
0.000 0.894 0.106
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.894 0.106
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.894 0.106
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.894 0.106
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.894 0.106
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.894 0.106
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.895 0.105
I62.1 Nontraumatic extradural haemorrhage
0.000 0.896 0.104
I68.0 Cerebral amyloid angiopathy
0.000 0.898 0.102
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.898 0.102
I95.2 Hypotension due to drugs
0.000 0.901 0.099
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.901 0.099
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.902 0.098
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.905 0.095
I95.0 Idiopathic hypotension
0.001 0.911 0.089
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.912 0.088
I35.1 Aortic (valve) insufficiency
0.000 0.912 0.087
I35.0 Aortic (valve) stenosis
0.000 0.916 0.084
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.918 0.082
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.918 0.082
S01.5 Open wound of lip and oral cavity
0.000 0.918 0.082
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.918 0.082
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.919 0.080
S01 Open wound of head
0.000 0.920 0.080
S01.3 Open wound of ear
0.000 0.923 0.077
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.925 0.075
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.926 0.074
S01.0 Open wound of scalp
0.000 0.928 0.072
I63.9 Cerebral infarction, unspecified
0.000 0.932 0.068
I63.8 Other cerebral infarction
0.000 0.934 0.066
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.934 0.066
S01.4 Open wound of cheek and temporomandibular area
0.000 0.934 0.066
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.936 0.064
S01.1 Open wound of eyelid and periocular area
0.000 0.939 0.061
S00-S09 Injuries to the head
0.000 0.940 0.060
S02 Fracture of skull and facial bones
0.000 0.941 0.059
S01.7 Multiple open wounds of head
0.000 0.943 0.057
S01.2 Open wound of nose
0.000 0.943 0.057
I61 Intracerebral haemorrhage
0.001 0.945 0.054
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.947 0.053
S01.8 Open wound of other parts of head
0.000 0.949 0.051
S02.2 Fracture of nasal bones
0.000 0.950 0.050
S02.1 Fracture of base of skull
0.000 0.951 0.049
S02.0 Fracture of vault of skull
0.000 0.952 0.048
S02.6 Fracture of mandible
0.000 0.952 0.048
S05 Injury of eye and orbit
0.000 0.952 0.048
S02.3 Fracture of orbital floor
0.000 0.952 0.048
S02.5 Fracture of tooth
0.000 0.953 0.047
R60 Oedema, not elsewhere classified
0.000 0.956 0.044
S08 Traumatic amputation of part of head
0.000 0.957 0.043
S07 Crushing injury of head
0.000 0.957 0.043
S04 Injury of cranial nerves
0.000 0.957 0.043
S03 Dislocation, sprain and strain of joints and ligaments of head
0.000 0.957 0.043
S02.8 Fractures of other skull and facial bones
0.000 0.957 0.043
S06 Intracranial injury
0.000 0.957 0.043
S02.20 Fracture of nasal bones (closed)
0.000 0.957 0.043
I61.8 Other intracerebral haemorrhage
0.000 0.957 0.042
S02.9 Fracture of skull and facial bones, part unspecified
0.000 0.957 0.043
S02.7 Multiple fractures involving skull and facial bones
0.000 0.957 0.043
S00 Superficial injury of head
0.000 0.958 0.042
S02.10 Fracture of base of skull (closed)
0.000 0.959 0.041
S05.1 Contusion of eyeball and orbital tissues
0.000 0.959 0.041
I88 Nonspecific lymphadenitis
0.000 0.959 0.041
S02.00 Fracture of vault of skull (closed)
0.000 0.959 0.040
S02.60 Fracture of mandible (closed)
0.000 0.960 0.040
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.001 0.960 0.040
I61.6 Intracerebral haemorrhage, multiple localised
0.001 0.960 0.039
S02.30 Fracture of orbital floor (closed)
0.000 0.961 0.039
S02.50 Fracture of tooth (closed)
0.000 0.961 0.039
I87 Other disorders of veins
0.000 0.961 0.039
S00.8 Superficial injury of other parts of head
0.000 0.961 0.039
S02.4 Fracture of malar and maxillary bones
0.000 0.961 0.038
I67.8 Other specified cerebrovascular diseases
0.000 0.963 0.036
S02.21 Fracture of nasal bones (open)
0.000 0.964 0.036
I61.3 Intracerebral haemorrhage in brain stem
0.001 0.964 0.035
S02.11 Fracture of base of skull (open)
0.000 0.965 0.035
S05.8 Other injuries of eye and orbit
0.000 0.965 0.035
S02.01 Fracture of vault of skull (open)
0.000 0.965 0.035
S02.61 Fracture of mandible (open)
0.000 0.965 0.035
I81 Portal vein thrombosis
0.000 0.965 0.035
S05.7 Avulsion of eye
0.000 0.966 0.034
S05.6 Penetrating wound of eyeball without foreign body
0.000 0.966 0.034
S05.5 Penetrating wound of eyeball with foreign body
0.000 0.966 0.034
S05.4 Penetrating wound of orbit with or without foreign body
0.000 0.966 0.034
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.000 0.966 0.034
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue
0.000 0.966 0.034
S02.31 Fracture of orbital floor (open)
0.000 0.966 0.034
S02.51 Fracture of tooth (open)
0.000 0.966 0.034
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.001 0.966 0.034
S06.8 Other intracranial injuries
0.000 0.966 0.034
I61.4 Intracerebral haemorrhage in cerebellum
0.001 0.966 0.033
S05.9 Injury of eye and orbit, part unspecified
0.000 0.966 0.034
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.966 0.034
S01.9 Open wound of head, part unspecified
0.000 0.967 0.033
I61.5 Intracerebral haemorrhage, intraventricular
0.001 0.967 0.032
I82 Other venous embolism and thrombosis
0.000 0.967 0.033
S00.0 Superficial injury of scalp
0.000 0.967 0.033
I87.8 Other specified disorders of veins
0.000 0.968 0.032
S06.0 Concussion
0.000 0.968 0.032
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.968 0.032

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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