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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0287
log Bayes Factor = 33.3095
contains 4 variants:
rs17072322
lBF = 5.235
Chr 4 : 182,742,909
rs12209307
lBF = 5.287
Chr 6 : 95,418,039
rs117597017
lBF = 9.812
Chr14 : 56,885,357
rs35942151
lBF = 5.509
Chr16 : 6,949,523
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
J44 Other chronic obstructive pulmonary disease
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
1.000 0.000 0.000
J09-J18 Influenza and pneumonia
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
1.000 0.000 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
1.000 0.000 0.000
I50 Heart failure
1.000 0.000 0.000
J18 Pneumonia, organism unspecified
1.000 0.000 0.000
I50.0 Congestive heart failure
1.000 0.000 0.000
I65.2 Occlusion and stenosis of carotid artery
1.000 0.000 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I74 Arterial embolism and thrombosis
1.000 0.000 0.000
I47 Paroxysmal tachycardia
0.999 0.001 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.999 0.001 0.000
J18.9 Pneumonia, unspecified
0.999 0.001 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.998 0.002 0.000
Y95 Nosocomial condition
0.998 0.002 0.000
J40-J47 Chronic lower respiratory diseases
0.998 0.002 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.997 0.003 0.000
I50.1 Left ventricular failure
0.995 0.005 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.995 0.005 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.993 0.007 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.992 0.008 0.000
I69 Sequelae of cerebrovascular disease
0.990 0.010 0.000
I95 Hypotension
0.989 0.011 0.000
Q80-Q89 Other congenital malformations
0.989 0.011 0.000
J60-J70 Lung diseases due to external agents
0.986 0.014 0.000
I63 Cerebral infarction
0.985 0.015 0.000
I95.1 Orthostatic hypotension
0.984 0.016 0.000
I31 Other diseases of pericardium
0.984 0.016 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.980 0.020 0.000
W00-W19 Falls
0.978 0.022 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.977 0.023 0.000
I26 Pulmonary embolism
0.971 0.029 0.000
J18.1 Lobar pneumonia, unspecified
0.971 0.029 0.000
I60 Subarachnoid haemorrhage
0.970 0.030 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.969 0.031 0.000
I31.9 Disease of pericardium, unspecified
0.964 0.036 0.000
J69 Pneumonitis due to solids and liquids
0.960 0.040 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.960 0.040 0.000
J00-J06 Acute upper respiratory infections
0.955 0.045 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.955 0.045 0.000
I72 Other aneurysm
0.954 0.046 0.000
W07 Fall involving chair
0.954 0.046 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.953 0.047 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.952 0.048 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.951 0.049 0.000
J15.1 Pneumonia due to Pseudomonas
0.947 0.053 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.947 0.053 0.000
I47.2 Ventricular tachycardia
0.946 0.054 0.000
W07.0 Home
0.943 0.057 0.000
J69.0 Pneumonitis due to food and vomit
0.942 0.058 0.000
W19 Unspecified fall
0.932 0.068 0.000
I47.1 Supraventricular tachycardia
0.931 0.069 0.000
I70 Atherosclerosis
0.930 0.070 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.930 0.070 0.000
Q85 Phakomatoses, not elsewhere classified
0.928 0.072 0.000
V40-V49 Car occupant injured in transport accident
0.928 0.072 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.923 0.077 0.000
Q50-Q56 Congenital malformations of genital organs
0.923 0.077 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.923 0.077 0.000
J86 Pyothorax
0.922 0.078 0.000
Q43 Other congenital malformations of intestine
0.919 0.081 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.917 0.083 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.914 0.086 0.000
J18.8 Other pneumonia, organism unspecified
0.909 0.091 0.000
Chapter V Mental and behavioural disorders
0.909 0.091 0.000
V20-V29 Motorcycle rider injured in transport accident
0.907 0.093 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.906 0.094 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.905 0.095 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.903 0.097 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.903 0.097 0.000
V80-V89 Other land transport accidents
0.902 0.098 0.000
Q87.4 Marfan's syndrome
0.901 0.099 0.000
W19.2 School, other institution and public administrative area
0.898 0.102 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.897 0.103 0.000
F17.2 Dependence syndrome
0.896 0.104 0.000
W19.4 Street and highway
0.895 0.105 0.000
J01 Acute sinusitis
0.892 0.108 0.000
D75 Other diseases of blood and blood-forming organs
0.892 0.108 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.891 0.109 0.000
D75.1 Secondary polycythaemia
0.884 0.116 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.883 0.117 0.000
J18.0 Bronchopneumonia, unspecified
0.879 0.121 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.876 0.124 0.000
Q43.8 Other specified congenital malformations of intestine
0.875 0.125 0.000
F80-F89 Disorders of psychological development
0.873 0.127 0.000
J11 Influenza, virus not identified
0.872 0.128 0.000
Q85.0 Neurofibromatosis (nonmalignant)
0.872 0.128 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.870 0.130 0.000
I72.3 Aneurysm of iliac artery
0.870 0.130 0.000
D76.3 Other histiocytosis syndromes
0.868 0.132 0.000
X50-X57 Overexertion, travel and privation
0.865 0.135 0.000
J15.5 Pneumonia due to Escherichia coli
0.865 0.135 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.863 0.137 0.000
W11 Fall on and from ladder
0.859 0.141 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.858 0.141 0.000
J02 Acute pharyngitis
0.857 0.143 0.000
F80 Specific developmental disorders of speech and language
0.855 0.145 0.000
I71 Aortic aneurysm and dissection
0.854 0.146 0.000
J41 Simple and mucopurulent chronic bronchitis
0.852 0.148 0.000
I95.9 Hypotension, unspecified
0.852 0.148 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.852 0.148 0.000
J10 Influenza due to identified influenza virus
0.851 0.149 0.000
J86.0 Pyothorax with fistula
0.845 0.155 0.000
F80.1 Expressive language disorder
0.843 0.157 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.841 0.159 0.000
J85 Abscess of lung and mediastinum
0.841 0.159 0.000
V90-V94 Water transport accidents
0.839 0.161 0.000
Y40 Systemic antibiotics
0.838 0.162 0.000
J14 Pneumonia due to Haemophilus influenzae
0.836 0.164 0.000
Q83 Congenital malformations of breast
0.835 0.165 0.000
F11 Mental and behavioural disorders due to use of opioids
0.834 0.166 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.834 0.166 0.000
Q25 Congenital malformations of great arteries
0.833 0.167 0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.831 0.169 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.831 0.169 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.829 0.171 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.824 0.176 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.821 0.179 0.000
J15.2 Pneumonia due to staphylococcus
0.821 0.179 0.000
I71.0 Dissection of aorta [any part]
0.820 0.180 0.000
I46 Cardiac arrest
0.818 0.182 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.817 0.182 0.000
D75.0 Familial erythrocytosis
0.817 0.183 0.000
W50-W64 Exposure to animate mechanical forces
0.816 0.184 0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified
0.816 0.184 0.000
J15.0 Pneumonia due to Klebsiella pneumoniae
0.815 0.185 0.000
J43 Emphysema
0.814 0.186 0.000
I61 Intracerebral haemorrhage
0.814 0.186 0.000
I74.5 Embolism and thrombosis of iliac artery
0.812 0.188 0.000
I72.0 Aneurysm of carotid artery
0.809 0.191 0.000
J86.9 Pyothorax without fistula
0.807 0.193 0.000
D80-D89 Certain disorders involving the immune mechanism
0.803 0.197 0.000
I95.2 Hypotension due to drugs
0.802 0.198 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.800 0.200 0.000
J60 Coalworker's pneumoconiosis
0.798 0.202 0.000
W75-W84 Other accidental threats to breathing
0.798 0.202 0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic
0.797 0.203 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.797 0.203 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.797 0.203 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.795 0.205 0.000
V27 Motorcycle rider injured in collision with fixed or stationary object
0.794 0.206 0.000
X60-X84 Intentional self-harm
0.789 0.211 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.788 0.212 0.000
I30 Acute pericarditis
0.788 0.212 0.000
V44 Car occupant injured in collision with heavy transport vehicle or bus
0.787 0.213 0.000
J00 Acute nasopharyngitis [common cold]
0.787 0.213 0.000
J01.9 Acute sinusitis, unspecified
0.786 0.214 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.784 0.216 0.000
I47.0 Reentry ventricular arrhythmia
0.784 0.216 0.000
Q50.4 Embryonic cyst of Fallopian tube
0.784 0.216 0.000
J11.1 Influenza with other respiratory manifestations, virus not identified
0.780 0.220 0.000
Q43.1 Hirschsprung's disease
0.779 0.221 0.000
W19.6 Industrial and construction area
0.778 0.222 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.778 0.222 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.777 0.223 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.775 0.225 0.000
Q25.1 Coarctation of aorta
0.775 0.225 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.772 0.228 0.000
W11.6 Industrial and construction area
0.771 0.229 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.771 0.229 0.000
I72.9 Aneurysm of unspecified site
0.771 0.229 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.769 0.231 0.000
Q45 Other congenital malformations of digestive system
0.768 0.232 0.000
V98-V99 Other and unspecified transport accidents
0.768 0.232 0.000
Y57 Other and unspecified drugs and medicaments
0.768 0.232 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.767 0.233 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.767 0.233 0.000
I40 Acute myocarditis
0.766 0.234 0.000
J70 Respiratory conditions due to other external agents
0.764 0.236 0.000
J64 Unspecified pneumoconiosis
0.764 0.236 0.000
Q35-Q37 Cleft lip and cleft palate
0.764 0.236 0.000
F17.3 Withdrawal state
0.763 0.237 0.000
X00-X09 Exposure to smoke, fire and flames
0.762 0.238 0.000
I31.3 Pericardial effusion (noninflammatory)
0.762 0.238 0.000
J15.9 Bacterial pneumonia, unspecified
0.762 0.238 0.000
X51 Travel and motion
0.761 0.239 0.000
J02.0 Streptococcal pharyngitis
0.761 0.239 0.000
I31.0 Chronic adhesive pericarditis
0.760 0.240 0.000
I46.9 Cardiac arrest, unspecified
0.759 0.241 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.759 0.241 0.000
W08 Fall involving other furniture
0.758 0.242 0.000
Y44 Agents primarily affecting blood constituents
0.757 0.243 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.755 0.245 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.755 0.245 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.754 0.246 0.000
D86 Sarcoidosis
0.754 0.246 0.000
J15.8 Other bacterial pneumonia
0.753 0.247 0.000
I00-I02 Acute rheumatic fever
0.753 0.247 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.752 0.248 0.000
V48 Car occupant injured in noncollision transport accident
0.750 0.250 0.000
V70-V79 Bus occupant injured in transport accident
0.750 0.250 0.000
W05 Fall involving wheelchair
0.749 0.251 0.000
J41.0 Simple chronic bronchitis
0.748 0.252 0.000
Q43.3 Congenital malformations of intestinal fixation
0.745 0.255 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.745 0.255 0.000
Q82 Other congenital malformations of skin
0.745 0.255 0.000
W00 Fall on same level involving ice and snow
0.743 0.257 0.000
V28 Motorcycle rider injured in noncollision transport accident
0.740 0.260 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.740 0.260 0.000
V29 Motorcycle rider injured in other and unspecified transport accidents
0.740 0.260 0.000
Q52 Other congenital malformations of female genitalia
0.737 0.263 0.000
J84 Other interstitial pulmonary diseases
0.736 0.264 0.000
V95-V97 Air and space transport accidents
0.736 0.264 0.000
J01.0 Acute maxillary sinusitis
0.736 0.264 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.734 0.266 0.000
I45 Other conduction disorders
0.734 0.266 0.000
Q83.1 Accessory breast
0.733 0.267 0.000
I70.0 Atherosclerosis of aorta
0.733 0.267 0.000
Y58 Bacterial vaccines
0.730 0.270 0.000
F11.3 Withdrawal state
0.730 0.270 0.000
Q28 Other congenital malformations of circulatory system
0.729 0.271 0.000
W10 Fall on and from stairs and steps
0.727 0.273 0.000
F11.1 Harmful use
0.726 0.274 0.000
I70.8 Atherosclerosis of other arteries
0.725 0.275 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.725 0.275 0.000
V93 Accident on board watercraft without accident to watercraft, not causing drowning and submersion
0.724 0.276 0.000
X20-X29 Contact with venomous animals and plants
0.724 0.276 0.000
I31.1 Chronic constrictive pericarditis
0.723 0.277 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.722 0.278 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.721 0.279 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.720 0.280 0.000
Q51 Congenital malformations of uterus and cervix
0.720 0.280 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.720 0.280 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.720 0.280 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.719 0.281 0.000
I72.8 Aneurysm of other specified arteries
0.719 0.281 0.000
J09 Influenza due to certain identified influenza virus
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.717 0.283 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
J18.2 Hypostatic pneumonia, unspecified
0.717 0.283 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.717 0.283 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.717 0.283 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
Y96 Work-related condition
0.716 0.284 0.000
Y97 Environmental-pollution-related condition
0.716 0.284 0.000
Y98 Lifestyle-related condition
0.716 0.284 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.716 0.284 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.716 0.284 0.000
Y41.5 Antiviral drugs
0.714 0.286 0.000
I72.1 Aneurysm of artery of upper extremity
0.714 0.286 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.714 0.286 0.000
J85.1 Abscess of lung with pneumonia
0.713 0.287 0.000
V27.4 Driver injured in traffic accident
0.712 0.288 0.000
J15.3 Pneumonia due to streptococcus, group B
0.712 0.288 0.000
I28 Other diseases of pulmonary vessels
0.712 0.288 0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.710 0.290 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.709 0.290 0.000
Y10-Y34 Event of undetermined intent
0.709 0.291 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.709 0.291 0.000
Q80 Congenital ichthyosis
0.709 0.291 0.000
Q81 Epidermolysis bullosa
0.709 0.291 0.000
Q84 Other congenital malformations of integument
0.709 0.291 0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.709 0.291 0.000
J17 Pneumonia in diseases classified elsewhere
0.709 0.291 0.000
V01-V09 Pedestrian injured in transport accident
0.707 0.293 0.000
J65 Pneumoconiosis associated with tuberculosis
0.707 0.293 0.000
J62 Pneumoconiosis due to dust containing silica
0.707 0.293 0.000
J63 Pneumoconiosis due to other inorganic dusts
0.707 0.293 0.000
J66 Airway disease due to specific organic dust
0.707 0.293 0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.707 0.293 0.000
I70.1 Atherosclerosis of renal artery
0.707 0.293 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.706 0.294 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.706 0.294 0.000
I65.1 Occlusion and stenosis of basilar artery
0.706 0.294 0.000
W14 Fall from tree
0.706 0.294 0.000
I31.2 Haemopericardium, not elsewhere classified
0.705 0.295 0.000
I31.8 Other specified diseases of pericardium
0.705 0.295 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.704 0.296 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.704 0.296 0.000
I30.1 Infective pericarditis
0.703 0.297 0.000
Q85.8 Other phakomatoses, not elsewhere classified
0.703 0.297 0.000
J04 Acute laryngitis and tracheitis
0.703 0.297 0.000
W04 Fall while being carried or supported by other persons
0.701 0.299 0.000
W09 Fall involving playground equipment
0.701 0.299 0.000
W12 Fall on and from scaffolding
0.701 0.299 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.701 0.299 0.000
W51 Striking against or bumped into by another person
0.701 0.299 0.000
Y49.2 Other and unspecified antidepressants
0.698 0.302 0.000
X59 Exposure to unspecified factor
0.698 0.302 0.000
I69.3 Sequelae of cerebral infarction
0.698 0.302 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.698 0.302 0.000
Q23 Congenital malformations of aortic and mitral valves
0.698 0.302 0.000
J69.8 Pneumonitis due to other solids and liquids
0.696 0.304 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.695 0.305 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.694 0.306 0.000
J01.8 Other acute sinusitis
0.694 0.306 0.000
Q85.9 Phakomatosis, unspecified
0.692 0.308 0.000
W20-W49 Exposure to inanimate mechanical forces
0.691 0.309 0.000
I36 Nonrheumatic tricuspid valve disorders
0.689 0.311 0.000
J69.1 Pneumonitis due to oils and essences
0.689 0.311 0.000
I60.8 Other subarachnoid haemorrhage
0.688 0.312 0.000
J85.0 Gangrene and necrosis of lung
0.687 0.313 0.000
J95-J99 Other diseases of the respiratory system
0.686 0.314 0.000
V44.5 Driver injured in traffic accident
0.686 0.314 0.000
D86.0 Sarcoidosis of lung
0.686 0.314 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.684 0.315 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.684 0.315 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.684 0.316 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.684 0.316 0.000
W07.1 Residential institution
0.684 0.316 0.000
W07.3 Sports and athletics area
0.684 0.316 0.000
W07.4 Street and highway
0.684 0.316 0.000
W07.5 Trade and service area
0.684 0.316 0.000
W07.6 Industrial and construction area
0.684 0.316 0.000
W07.7 Farm
0.684 0.316 0.000
W07.8 Other specified place
0.684 0.316 0.000
W07.2 School, other institution and public administrative area
0.684 0.316 0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance
0.683 0.317 0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature
0.683 0.317 0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs
0.683 0.317 0.000
Q87.3 Congenital malformation syndromes involving early overgrowth
0.683 0.317 0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes
0.683 0.317 0.000
F30-F39 Mood [affective] disorders
0.682 0.318 0.000
Q55 Other congenital malformations of male genital organs
0.682 0.318 0.000
Y77 Ophthalmic devices associated with adverse incidents
0.682 0.318 0.000
J43.9 Emphysema, unspecified
0.681 0.319 0.000
V43 Car occupant injured in collision with car, pick-up truck or van
0.678 0.322 0.000
I63.8 Other cerebral infarction
0.678 0.322 0.000
I95.0 Idiopathic hypotension
0.677 0.323 0.000
J01.2 Acute ethmoidal sinusitis
0.674 0.326 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.674 0.326 0.000
Y41.1 Antimycobacterial drugs
0.674 0.326 0.000
X51.9 Unspecified place
0.672 0.328 0.000
J02.9 Acute pharyngitis, unspecified
0.672 0.328 0.000
F31 Bipolar affective disorder
0.671 0.329 0.000
Q50.5 Embryonic cyst of broad ligament
0.671 0.329 0.000
V49.9 Car occupant [any] injured in unspecified traffic accident
0.670 0.330 0.000
I42 Cardiomyopathy
0.669 0.331 0.000
Y00-Y09 Assault
0.669 0.331 0.000
W19.7 Farm
0.668 0.332 0.000
W19.0 Home
0.668 0.332 0.000
W19.5 Trade and service area
0.668 0.332 0.000
W19.8 Other specified place
0.668 0.332 0.000
Y57.6 Other diagnostic agents
0.668 0.332 0.000
Y40.4 Tetracyclines
0.668 0.332 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.668 0.332 0.000
I70.9 Generalised and unspecified atherosclerosis
0.667 0.333 0.000
V53 Occupant of pick-up truck or van injured in collision with car, pick-up truck or van
0.667 0.333 0.000
J10.0 Influenza with pneumonia, influenza virus identified
0.667 0.333 0.000
D86.3 Sarcoidosis of skin
0.667 0.333 0.000
Q85.1 Tuberous sclerosis
0.665 0.334 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.665 0.335 0.000
V40 Car occupant injured in collision with pedestrian or animal
0.665 0.335 0.000
V41 Car occupant injured in collision with pedal cycle
0.665 0.335 0.000
V42 Car occupant injured in collision with two- or three-wheeled motor vehicle
0.665 0.335 0.000
V45 Car occupant injured in collision with railway train or railway vehicle
0.665 0.335 0.000
V46 Car occupant injured in collision with other nonmotor vehicle
0.665 0.335 0.000
V47 Car occupant injured in collision with fixed or stationary object
0.665 0.335 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.663 0.336 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.663 0.337 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.662 0.338 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.662 0.338 0.000
X78 Intentional self-harm by sharp object
0.662 0.338 0.000
I74.8 Embolism and thrombosis of other arteries
0.661 0.338 0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa
0.660 0.340 0.000
Y42.5 Other oestrogens and progestogens
0.660 0.340 0.000
Q24 Other congenital malformations of heart
0.659 0.341 0.000
Q43.2 Other congenital functional disorders of colon
0.659 0.341 0.000
Q43.4 Duplication of intestine
0.659 0.341 0.000
Q43.5 Ectopic anus
0.659 0.341 0.000
Q43.6 Congenital fistula of rectum and anus
0.659 0.341 0.000
Q43.7 Persistent cloaca
0.659 0.341 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.658 0.342 0.000
D55-D59 Haemolytic anaemias
0.657 0.342 0.000
Y40.7 Antifungal antibiotics, systemically used
0.656 0.344 0.000
Q43.9 Congenital malformation of intestine, unspecified
0.655 0.345 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.654 0.345 0.000
Y59 Other and unspecified vaccines and biological substances
0.654 0.346 0.000
Q40 Other congenital malformations of upper alimentary tract
0.653 0.347 0.000
F84 Pervasive developmental disorders
0.653 0.347 0.000
Y81 General- and plastic-surgery devices associated with adverse incidents
0.653 0.347 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.653 0.347 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.651 0.348 0.000
V20 Motorcycle rider injured in collision with pedestrian or animal
0.650 0.349 0.000
V21 Motorcycle rider injured in collision with pedal cycle
0.650 0.349 0.000
V22 Motorcycle rider injured in collision with two- or three-wheeled motor vehicle
0.650 0.349 0.000
V24 Motorcycle rider injured in collision with heavy transport vehicle or bus
0.650 0.349 0.000
V25 Motorcycle rider injured in collision with railway train or railway vehicle
0.650 0.349 0.000
V26 Motorcycle rider injured in collision with other nonmotor vehicle
0.650 0.349 0.000
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.649 0.351 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.649 0.351 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.649 0.351 0.000
D74 Methaemoglobinaemia
0.649 0.351 0.000
D84 Other immunodeficiencies
0.648 0.352 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.648 0.352 0.000
Q26 Congenital malformations of great veins
0.648 0.352 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.648 0.352 0.000
I97.1 Other functional disturbances following cardiac surgery
0.647 0.352 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.647 0.353 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.647 0.353 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.647 0.353 0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents
0.647 0.353 0.000
V81 Occupant of railway train or railway vehicle injured in transport accident
0.647 0.353 0.000
V82 Occupant of streetcar injured in transport accident
0.647 0.353 0.000
V83 Occupant of special vehicle mainly used on industrial premises injured in transport accident
0.647 0.353 0.000
V84 Occupant of special vehicle mainly used in agriculture injured in transport accident
0.647 0.353 0.000
V85 Occupant of special construction vehicle injured in transport accident
0.647 0.353 0.000
V86 Occupant of special all-terrain or other motor vehicle designed primarily for off-road use, injured in transport accident
0.647 0.353 0.000
V87 Traffic accident of specified type but victim's mode of transport unknown
0.647 0.353 0.000
V88 Nontraffic accident of specified type but victim's mode of transport unknown
0.647 0.353 0.000
W64 Exposure to other and unspecified animate mechanical forces
0.646 0.354 0.000
Y53.4 Other laxatives
0.646 0.354 0.000
Y40.6 Rifamycins
0.643 0.357 0.000
Q25.0 Patent ductus arteriosus
0.643 0.357 0.000
V48.0 Driver injured in nontraffic accident
0.643 0.357 0.000
F17.0 Acute intoxication
0.643 0.357 0.000
F17.4 Withdrawal state with delirium
0.643 0.357 0.000
F17.5 Psychotic disorder
0.643 0.357 0.000
F17.6 Amnesic syndrome
0.643 0.357 0.000
F17.7 Residual and late-onset psychotic disorder
0.643 0.357 0.000
F17.8 Other mental and behavioural disorders
0.643 0.357 0.000
F17.9 Unspecified mental and behavioural disorder
0.643 0.357 0.000
J12 Viral pneumonia, not elsewhere classified
0.642 0.358 0.000
I62 Other nontraumatic intracranial haemorrhage
0.642 0.358 0.000
D75.9 Disease of blood and blood-forming organs, unspecified
0.642 0.358 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.642 0.358 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.641 0.359 0.000
J01.1 Acute frontal sinusitis
0.640 0.360 0.000
J01.3 Acute sphenoidal sinusitis
0.640 0.360 0.000
J01.4 Acute pansinusitis
0.640 0.360 0.000
V28.2 Unspecified motorcycle rider injured in nontraffic accident
0.640 0.360 0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.639 0.360 0.000
X50 Overexertion and strenuous or repetitive movements
0.638 0.362 0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]
0.638 0.362 0.000
I95.8 Other hypotension
0.638 0.362 0.000
Q27 Other congenital malformations of peripheral vascular system
0.637 0.363 0.000
V58 Occupant of pick-up truck or van injured in noncollision transport accident
0.637 0.363 0.000
V98 Other specified transport accidents
0.635 0.365 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.635 0.365 0.000
Q45.8 Other specified congenital malformations of digestive system
0.635 0.365 0.000
J67.2 Bird fancier's lung
0.634 0.366 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.634 0.366 0.000
I72.4 Aneurysm of artery of lower extremity
0.634 0.366 0.000
I45.9 Conduction disorder, unspecified
0.633 0.367 0.000
Y40.5 Aminoglycosides
0.633 0.367 0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.633 0.367 0.000
D76.1 Haemophagocytic lymphohistiocytosis
0.633 0.367 0.000
D76.2 Haemophagocytic syndrome, infection-associated
0.633 0.367 0.000
I45.5 Other specified heart block
0.632 0.368 0.000
I72.2 Aneurysm of renal artery
0.632 0.368 0.000
D72 Other disorders of white blood cells
0.631 0.369 0.000
D86.8 Sarcoidosis of other and combined sites
0.628 0.372 0.000
J11.0 Influenza with pneumonia, virus not identified
0.628 0.372 0.000
Y40.9 Systemic antibiotic, unspecified
0.628 0.372 0.000
J02.8 Acute pharyngitis due to other specified organisms
0.626 0.374 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.626 0.374 0.000
W11.5 Trade and service area
0.626 0.374 0.000
F82 Specific developmental disorder of motor function
0.626 0.374 0.000
F83 Mixed specific developmental disorders
0.626 0.374 0.000
F88 Other disorders of psychological development
0.626 0.374 0.000
F89 Unspecified disorder of psychological development
0.626 0.374 0.000
J11.8 Influenza with other manifestations, virus not identified
0.625 0.374 0.000
I05-I09 Chronic rheumatic heart diseases
0.624 0.376 0.000
Y40.3 Macrolides
0.623 0.377 0.000
F31.7 Bipolar affective disorder, currently in remission
0.623 0.377 0.000
W87 Exposure to unspecified electric current
0.622 0.378 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.620 0.379 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.620 0.380 0.000
X52 Prolonged stay in weightless environment
0.620 0.380 0.000
X53 Lack of food
0.620 0.380 0.000
X54 Lack of water
0.620 0.380 0.000
X57 Unspecified privation
0.620 0.380 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.620 0.380 0.000
V29.3 Motorcycle rider [any] injured in unspecified nontraffic accident
0.619 0.380 0.000
W08.9 Unspecified place
0.618 0.382 0.000
W80 Inhalation and ingestion of other objects causing obstruction of respiratory tract
0.618 0.382 0.000
W51.9 Unspecified place
0.618 0.382 0.000
Y49.5 Other antipsychotics and neuroleptics
0.617 0.383 0.000
W11.1 Residential institution
0.616 0.384 0.000
W11.2 School, other institution and public administrative area
0.616 0.384 0.000
W11.3 Sports and athletics area
0.616 0.384 0.000
W11.4 Street and highway
0.616 0.384 0.000
W11.7 Farm
0.616 0.384 0.000
W11.0 Home
0.616 0.384 0.000
W11.8 Other specified place
0.616 0.384 0.000
W11.9 Unspecified place
0.616 0.384 0.000
I49 Other cardiac arrhythmias
0.616 0.384 0.000
Y70 Anaesthesiology devices associated with adverse incidents
0.615 0.384 0.000
Y71 Cardiovascular devices associated with adverse incidents
0.615 0.384 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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