TreeWAS – Variant ID: Affx-28455150

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	0.000	0.000	1.000
L40.5 Arthropathic psoriasis	0.000	0.000	1.000
L40 Psoriasis	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
E10.9 Without complications	0.000	0.000	1.000
E03 Other hypothyroidism	0.000	0.002	0.998
E83.1 Disorders of iron metabolism	0.998	0.002	0.000
G35 Multiple sclerosis	0.997	0.003	0.000
E00-E07 Disorders of thyroid gland	0.000	0.004	0.996
E10-E14 Diabetes mellitus	0.000	0.006	0.994
E10.3 With ophthalmic complications	0.000	0.010	0.990
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.011	0.989
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.017	0.983
E05.9 Thyrotoxicosis, unspecified	0.000	0.026	0.974
L40-L45 Papulosquamous disorders	0.000	0.087	0.913
E10.4 With neurological complications	0.000	0.091	0.909
L40.0 Psoriasis vulgaris	0.000	0.111	0.889
L43 Lichen planus	0.000	0.111	0.889
E10.1 With ketoacidosis	0.000	0.114	0.886
E10.2 With renal complications	0.000	0.124	0.875
L43.9 Lichen planus, unspecified	0.000	0.134	0.866
L40.8 Other psoriasis	0.000	0.146	0.854
E07 Other disorders of thyroid	0.000	0.157	0.843
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.197	0.803
E78.0 Pure hypercholesterolaemia	0.000	0.198	0.802
E14 Unspecified diabetes mellitus	0.000	0.200	0.800
E10.8 With unspecified complications	0.000	0.209	0.791
E10.0 With coma	0.000	0.214	0.786
E78.5 Hyperlipidaemia, unspecified	0.000	0.217	0.783
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.221	0.779
E70-E90 Metabolic disorders	0.010	0.222	0.769
E03.8 Other specified hypothyroidism	0.000	0.236	0.764
E07.9 Disorder of thyroid, unspecified	0.000	0.241	0.759
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.755	0.245	0.000
E13 Other specified diabetes mellitus	0.000	0.252	0.748
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.256	0.744
G35-G37 Demyelinating diseases of the central nervous system	0.743	0.257	0.000
L42 Pityriasis rosea	0.000	0.269	0.731
E78.8 Other disorders of lipoprotein metabolism	0.000	0.274	0.726
E14.3 With ophthalmic complications	0.000	0.282	0.718
L40.4 Guttate psoriasis	0.000	0.283	0.717
L40.2 Acrodermatitis continua	0.000	0.283	0.717
L40.1 Generalised pustular psoriasis	0.000	0.283	0.717
E10.7 With multiple complications	0.000	0.283	0.717
E03.5 Myxoedema coma	0.000	0.284	0.716
E03.4 Atrophy of thyroid (acquired)	0.000	0.284	0.716
E03.3 Postinfectious hypothyroidism	0.000	0.284	0.716
E03.1 Congenital hypothyroidism without goitre	0.000	0.284	0.716
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.284	0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.286	0.714
E00 Congenital iodine-deficiency syndrome	0.000	0.286	0.714
E12 Malnutrition-related diabetes mellitus	0.000	0.287	0.713
E05.5 Thyroid crisis or storm	0.000	0.295	0.705
E05.4 Thyrotoxicosis factitia	0.000	0.295	0.705
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.295	0.705
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.295	0.705
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.302	0.698
G37 Other demyelinating diseases of central nervous system	0.692	0.308	0.000
L43.8 Other lichen planus	0.000	0.309	0.691
E05.8 Other thyrotoxicosis	0.000	0.325	0.675
L40.3 Pustulosis palmaris et plantaris	0.000	0.327	0.673
E10.6 With other specified complications	0.000	0.331	0.668
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.340	0.660
L44 Other papulosquamous disorders	0.000	0.345	0.655
L41 Parapsoriasis	0.000	0.345	0.655
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.345	0.655
E78.1 Pure hyperglyceridaemia	0.000	0.351	0.649
L43.3 Subacute (active) lichen planus	0.000	0.363	0.637
L43.2 Lichenoid drug reaction	0.000	0.363	0.637
L43.1 Bullous lichen planus	0.000	0.363	0.637
L43.0 Hypertrophic lichen planus	0.000	0.363	0.637
G37.9 Demyelinating disease of central nervous system, unspecified	0.623	0.377	0.000
E10.5 With peripheral circulatory complications	0.000	0.390	0.610
E07.1 Dyshormogenetic goitre	0.000	0.395	0.604
E07.0 Hypersecretion of calcitonin	0.000	0.395	0.604
E14.1 With ketoacidosis	0.000	0.397	0.603
G37.8 Other specified demyelinating diseases of central nervous system	0.597	0.403	0.000
E40-E46 Malnutrition	0.000	0.404	0.596
E14.4 With neurological complications	0.000	0.411	0.589
J45.9 Asthma, unspecified	0.000	0.416	0.584
E06 Thyroiditis	0.000	0.422	0.577
E78.6 Lipoprotein deficiency	0.000	0.424	0.575
E78.3 Hyperchylomicronaemia	0.000	0.424	0.575
E14.5 With peripheral circulatory complications	0.000	0.425	0.575
E11 Non-insulin-dependent diabetes mellitus	0.000	0.426	0.574
E14.8 With unspecified complications	0.000	0.426	0.574
E14.7 With multiple complications	0.000	0.426	0.574
E14.2 Withrenal complications	0.000	0.426	0.574
E14.0 With coma	0.000	0.426	0.574
E13.9 Without complications	0.000	0.428	0.572
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.430	0.570
E78.2 Mixed hyperlipidaemia	0.000	0.432	0.568
I83 Varicose veins of lower extremities	0.560	0.440	0.000
E77 Disorders of glycoprotein metabolism	0.007	0.442	0.551
E76 Disorders of glycosaminoglycan metabolism	0.007	0.442	0.551
E72 Other disorders of amino-acid metabolism	0.007	0.442	0.551
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.007	0.442	0.551
E70 Disorders of aromatic amino-acid metabolism	0.007	0.442	0.551
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.007	0.442	0.551
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.007	0.444	0.549
E84 Cystic fibrosis	0.007	0.453	0.540
E11.1 With ketoacidosis	0.000	0.455	0.545
E14.6 With other specified complications	0.000	0.461	0.539
I83.0 Varicose veins of lower extremities with ulcer	0.538	0.462	0.000
E13.8 With unspecified complications	0.000	0.464	0.536
E13.7 With multiple complications	0.000	0.464	0.536
E13.6 With other specified complications	0.000	0.464	0.536
E13.5 With peripheral circulatory complications	0.000	0.464	0.536
E13.4 With neurological complications	0.000	0.464	0.536
E13.3 With ophthalmic complications	0.000	0.464	0.536
E13.2 With renal complications	0.000	0.464	0.536
E13.1 With ketoacidosis	0.000	0.464	0.536
E13.0 With coma	0.000	0.464	0.536
G36 Other acute disseminated demyelination	0.533	0.467	0.000
E07.8 Other specified disorders of thyroid	0.000	0.468	0.532
E78.4 Other hyperlipidaemia	0.000	0.484	0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.488	0.512
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.488	0.512
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.488	0.512
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.488	0.512
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.488	0.512
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.488	0.512
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.488	0.512
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.488	0.512
E12.9 Without complications	0.000	0.489	0.511
E12.8 With unspecified complications	0.000	0.489	0.511
E12.7 With multiple complications	0.000	0.489	0.511
E12.6 With other specified complications	0.000	0.489	0.511
E12.5 With peripheral circulatory complications	0.000	0.489	0.511
E12.4 With neurological complications	0.000	0.489	0.511
E12.3 With ophthalmic complications	0.000	0.489	0.511
E12.2 With renal complications	0.000	0.489	0.511
E12.1 With ketoacidosis	0.000	0.489	0.511
E12.0 With coma	0.000	0.489	0.511
E83 Disorders of mineral metabolism	0.219	0.491	0.290
E15 Nondiabetic hypoglycaemic coma	0.000	0.499	0.501
G37.5 Concentric sclerosis [Balo]	0.496	0.504	0.000
G37.4 Subacute necrotising myelitis	0.496	0.504	0.000
G37.2 Central pontine myelinolysis	0.496	0.504	0.000
G37.1 Central demyelination of corpus callosum	0.496	0.504	0.000
G37.0 Diffuse sclerosis	0.496	0.504	0.000
E74 Other disorders of carbohydrate metabolism	0.007	0.507	0.485
E79 Disorders of purine and pyrimidine metabolism	0.008	0.508	0.484
E16 Other disorders of pancreatic internal secretion	0.000	0.510	0.490
E11.0 With coma	0.000	0.519	0.481
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.473	0.527	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.002	0.528	0.470
L41.9 Parapsoriasis, unspecified	0.000	0.530	0.470
L41.8 Other parapsoriasis	0.000	0.530	0.470
L41.5 Retiform parapsoriasis	0.000	0.530	0.470
L41.4 Large plaque parapsoriasis	0.000	0.530	0.470
L41.3 Small plaque parapsoriasis	0.000	0.530	0.470
L41.2 Lymphomatoid papulosis	0.000	0.530	0.470
L41.1 Pityriasis lichenoides chronica	0.000	0.530	0.470
L41.0 Pityriasis lichenoides et varioliformis acuta	0.000	0.530	0.470
L44.9 Papulosquamous disorder, unspecified	0.000	0.530	0.470
L44.8 Other specified papulosquamous disorders	0.000	0.530	0.470
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.000	0.530	0.470
L44.3 Lichen ruber moniliformis	0.000	0.530	0.470
L44.2 Lichen striatus	0.000	0.530	0.470
L44.1 Lichen nitidus	0.000	0.530	0.470
L44.0 Pityriasis rubra pilaris	0.000	0.530	0.470
E73 Lactose intolerance	0.008	0.552	0.440
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.435	0.565	0.000
E11.2 With renal complications	0.000	0.567	0.433
E50-E64 Other nutritional deficiencies	0.000	0.570	0.430
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.572	0.427
E45 Retarded development following protein-energy malnutrition	0.000	0.572	0.427
E43 Unspecified severe protein-energy malnutrition	0.000	0.572	0.427
E42 Marasmic kwashiorkor	0.000	0.572	0.427
E41 Nutritional marasmus	0.000	0.572	0.427
E40 Kwashiorkor	0.000	0.572	0.427
E11.6 With other specified complications	0.000	0.573	0.427
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.576	0.424
E06.5 Other chronic thyroiditis	0.000	0.586	0.414
E06.4 Drug-induced thyroiditis	0.000	0.586	0.414
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.586	0.414
E06.1 Subacute thyroiditis	0.000	0.586	0.414
E06.0 Acute thyroiditis	0.000	0.586	0.414
E11.7 With multiple complications	0.000	0.588	0.412
E85 Amyloidosis	0.008	0.591	0.402
E89.3 Postprocedural hypopituitarism	0.001	0.598	0.401
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.005	0.600	0.395
E70.8 Other disorders of aromatic amino-acid metabolism	0.005	0.600	0.395
E70.3 Albinism	0.005	0.600	0.395
E70.2 Disorders of tyrosine metabolism	0.005	0.600	0.395
E70.1 Other hyperphenylalaninaemias	0.005	0.600	0.395
E70.0 Classical phenylketonuria	0.005	0.600	0.395
E71.3 Disorders of fatty-acid metabolism	0.005	0.600	0.395
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.005	0.600	0.395
E71.1 Other disorders of branched-chain amino-acid metabolism	0.005	0.600	0.395
E71.0 Maple-syrup-urine disease	0.005	0.600	0.395
E72.9 Disorder of amino-acid metabolism, unspecified	0.005	0.600	0.395
E72.8 Other specified disorders of amino-acid metabolism	0.005	0.600	0.395
E72.5 Disorders of glycine metabolism	0.005	0.600	0.395
E72.4 Disorders of ornithine metabolism	0.005	0.600	0.395
E72.3 Disorders of lysine and hydroxylysine metabolism	0.005	0.600	0.395
E72.2 Disorders of urea cycle metabolism	0.005	0.600	0.395
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.005	0.600	0.395
E72.0 Disorders of amino-acid transport	0.005	0.600	0.395
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.005	0.600	0.395
E76.8 Other disorders of glucosaminoglycan metabolism	0.005	0.600	0.395
E76.3 Mucopolysaccharidosis, unspecified	0.005	0.600	0.395
E76.2 Other mucopolysaccharidoses	0.005	0.600	0.395
E76.1 Mucopolysaccharidosis, type II	0.005	0.600	0.395
E76.0 Mucopolysaccharidosis, type I	0.005	0.600	0.395
E77.9 Disorder of glycoprotein metabolism, unspecified	0.005	0.600	0.395
E77.8 Other disorders of glycoprotein metabolism	0.005	0.600	0.395
E77.1 Defects in glycoprotein degradation	0.005	0.600	0.395
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.005	0.600	0.395
E75.6 Lipid storage disorder, unspecified	0.005	0.601	0.394
E75.4 Neuronal ceroid lipofuscinosis	0.005	0.601	0.394
E75.3 Sphingolipidosis, unspecified	0.005	0.601	0.394
E75.2 Other sphingolipidosis	0.005	0.601	0.394
E75.1 Other gangliosidosis	0.005	0.601	0.394
E75.0 GM2 gangliosidosis	0.005	0.601	0.394
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.602	0.398
E14.9 Without complications	0.000	0.603	0.397
E75.5 Other lipid storage disorders	0.005	0.604	0.391
E84.8 Cystic fibrosis with other manifestations	0.005	0.608	0.387
E84.1 Cystic fibrosis with intestinal manifestations	0.005	0.608	0.387
E84.0 Cystic fibrosis with pulmonary manifestations	0.005	0.608	0.387
E65-E68 Obesity and other hyperalimentation	0.000	0.612	0.388
E80 Disorders of porphyrin and bilirubin metabolism	0.008	0.617	0.375
E16.1 Other hypoglycaemia	0.000	0.618	0.382
G36.9 Acute disseminated demyelination, unspecified	0.382	0.618	0.000
G36.8 Other specified acute disseminated demyelination	0.382	0.618	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.382	0.618	0.000
G36.0 Neuromyelitis optica [Devic]	0.382	0.618	0.000
E84.9 Cystic fibrosis, unspecified	0.005	0.619	0.375
E06.9 Thyroiditis, unspecified	0.000	0.621	0.379
E83.9 Disorder of mineral metabolism, unspecified	0.157	0.635	0.208
E83.8 Other disorders of mineral metabolism	0.157	0.635	0.208
E83.2 Disorders of zinc metabolism	0.157	0.635	0.208
E83.0 Disorders of copper metabolism	0.157	0.635	0.208
E74.9 Disorder of carbohydrate metabolism, unspecified	0.005	0.647	0.348
E74.8 Other specified disorders of carbohydrate metabolism	0.005	0.647	0.348
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.005	0.647	0.348
E74.2 Disorders of galactose metabolism	0.005	0.647	0.348
E74.1 Disorders of fructose metabolism	0.005	0.647	0.348
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.006	0.647	0.347
E79.8 Other disorders of purine and pyrimidine metabolism	0.006	0.647	0.347
E79.1 Lesch-Nyhan syndrome	0.006	0.647	0.347
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.649	0.351
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.649	0.351
E16.4 Abnormal secretion of gastrin	0.000	0.649	0.351
E16.3 Increased secretion of glucagon	0.000	0.649	0.351
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.001	0.655	0.343
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.002	0.662	0.337
E89.8 Other postprocedural endocrine and metabolic disorders	0.002	0.662	0.337
E89.5 Postprocedural testicular hypofunction	0.002	0.662	0.337
E89.1 Postprocedural hypoinsulinaemia	0.002	0.662	0.337
E06.3 Autoimmune thyroiditis	0.000	0.669	0.331
E74.3 Other disorders of intestinal carbohydrate absorption	0.005	0.671	0.324
E89.2 Postprocedural hypoparathyroidism	0.001	0.674	0.325
E11.8 With unspecified complications	0.000	0.675	0.325
E89.4 Postprocedural ovarian failure	0.002	0.676	0.323
E73.8 Other lactose intolerance	0.006	0.679	0.315
E73.1 Secondary lactase deficiency	0.006	0.679	0.315
E73.0 Congenital lactase deficiency	0.006	0.679	0.315
E20-E35 Disorders of other endocrine glands	0.000	0.679	0.321
E74.0 Glycogen storage disease	0.006	0.681	0.313
E11.5 With peripheral circulatory complications	0.000	0.683	0.317
E46 Unspecified protein-energy malnutrition	0.000	0.685	0.314
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.691	0.308
E63 Other nutritional deficiencies	0.000	0.691	0.308
E51 Thiamine deficiency	0.000	0.691	0.308
E50 Vitamin A deficiency	0.000	0.691	0.308
E60 Dietary zinc deficiency	0.000	0.691	0.308
E59 Dietary selenium deficiency	0.000	0.691	0.308
E58 Dietary calcium deficiency	0.000	0.691	0.308
E54 Ascorbic acid deficiency	0.000	0.691	0.308
E52 Niacin deficiency [pellagra]	0.000	0.691	0.308
E44.1 Mild protein-energy malnutrition	0.000	0.693	0.306
E44.0 Moderate protein-energy malnutrition	0.000	0.693	0.306
K90 Intestinal malabsorption	0.000	0.698	0.302
E11.3 With ophthalmic complications	0.000	0.699	0.301
E56 Other vitamin deficiencies	0.000	0.699	0.300
E80.6 Other disorders of bilirubin metabolism	0.005	0.699	0.296
M45 Ankylosing spondylitis	0.000	0.701	0.299
E85.8 Other amyloidosis	0.006	0.706	0.288
E85.2 Heredofamilial amyloidosis, unspecified	0.006	0.706	0.288
E85.1 Neuropathic heredofamilial amyloidosis	0.006	0.706	0.288
E85.0 Nonneuropathic heredofamilial amyloidosis	0.006	0.706	0.288
E83.4 Disorders of magnesium metabolism	0.034	0.708	0.258
E61 Deficiency of other nutrient elements	0.000	0.709	0.291
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.007	0.714	0.280
E83.3 Disorders of phosphorus metabolism	0.169	0.714	0.117
E55 Vitamin D deficiency	0.000	0.715	0.285
E67 Other hyperalimentation	0.000	0.722	0.278
E68 Sequelae of hyperalimentation	0.000	0.722	0.278
E88 Other metabolic disorders	0.009	0.722	0.268
E85.9 Amyloidosis, unspecified	0.005	0.725	0.270
E80.7 Disorder of bilirubin metabolism, unspecified	0.006	0.725	0.269
E80.5 Crigler-Najjar syndrome	0.006	0.725	0.269
E80.3 Defects of catalase and peroxydase	0.006	0.725	0.269
E80.2 Other porphyria	0.006	0.725	0.269
E80.0 Hereditary erythropoietic porphyria	0.006	0.725	0.269
E85.3 Secondary systemic amyloidosis	0.006	0.730	0.264
E23 Hypofunction and other disorders of pituitary gland	0.000	0.733	0.267
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.739	0.260
E24 Cushing's syndrome	0.000	0.741	0.259
E80.1 Porphyria cutanea tarda	0.006	0.752	0.242
E78.9 Disorder of lipoprotein metabolism, unspecified	0.001	0.757	0.242
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.759	0.241
E65 Localised adiposity	0.000	0.765	0.235
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.767	0.233
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.770	0.230
E32 Diseases of thymus	0.000	0.770	0.230
E31 Polyglandular dysfunction	0.000	0.770	0.230
E30 Disorders of puberty, not elsewhere classified	0.000	0.770	0.230
E25 Adrenogenital disorders	0.000	0.770	0.230
E26 Hyperaldosteronism	0.000	0.777	0.222
E50.9 Vitamin A deficiency, unspecified	0.000	0.779	0.221
E50.8 Other manifestations of vitamin A deficiency	0.000	0.779	0.221
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.779	0.221
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.779	0.221
E50.5 Vitamin A deficiency with night blindness	0.000	0.779	0.221
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.779	0.221
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.779	0.221
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.779	0.221
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.779	0.221
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.779	0.221
E51.9 Thiamine deficiency, unspecified	0.000	0.779	0.221
E51.8 Other manifestations of thiamine deficiency	0.000	0.779	0.221
E51.2 Wernicke's encephalopathy	0.000	0.779	0.221
E51.1 Beriberi	0.000	0.779	0.221
E63.9 Nutritional deficiency, unspecified	0.000	0.779	0.221
E63.8 Other specified nutritional deficiencies	0.000	0.779	0.221
E63.1 Imbalance of constituents of food intake	0.000	0.779	0.221
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.779	0.221
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.779	0.221
E64.8 Sequelae of other nutritional deficiencies	0.000	0.779	0.221
E64.3 Sequelae of rickets	0.000	0.779	0.221
E64.2 Sequelae of vitamin C deficiency	0.000	0.779	0.221
E64.1 Sequelae of vitamin A deficiency	0.000	0.779	0.221
E64.0 Sequelae of protein-energy malnutrition	0.000	0.779	0.221
E23.7 Disorder of pituitary gland, unspecified	0.000	0.779	0.221
E85.4 Organ-limited amyloidosis	0.006	0.780	0.214
E23.2 Diabetes insipidus	0.000	0.782	0.218
E28 Ovarian dysfunction	0.000	0.782	0.218
E29 Testicular dysfunction	0.000	0.783	0.217
K90.3 Pancreatic steatorrhoea	0.000	0.784	0.216
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.784	0.216
K90.1 Tropical sprue	0.000	0.784	0.216
E56.9 Vitamin deficiency, unspecified	0.000	0.784	0.216
E56.8 Deficiency of other vitamins	0.000	0.784	0.216
E56.0 Deficiency of vitamin E	0.000	0.784	0.216
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.785	0.215
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.785	0.215
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.785	0.215
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.785	0.215
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.785	0.215
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.785	0.215
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.785	0.215
E88.2 Lipomatosis, not elsewhere classified	0.006	0.786	0.209
E24.9 Cushing's syndrome, unspecified	0.000	0.786	0.214
K90.8 Other intestinal malabsorption	0.000	0.787	0.213
E61.2 Magnesium deficiency	0.000	0.787	0.213
E73.9 Lactose intolerance, unspecified	0.007	0.789	0.204
E88.8 Other specified metabolic disorders	0.006	0.790	0.204
E61.9 Deficiency of nutrient element, unspecified	0.000	0.791	0.209
E61.8 Deficiency of other specified nutrient elements	0.000	0.791	0.209
E61.7 Deficiency of multiple nutrient elements	0.000	0.791	0.209
E61.6 Vanadium deficiency	0.000	0.791	0.209
E61.5 Molybdenum deficiency	0.000	0.791	0.209
E61.4 Chromium deficiency	0.000	0.791	0.209
E61.3 Manganese deficiency	0.000	0.791	0.209
E61.0 Copper deficiency	0.000	0.791	0.209
E56.1 Deficiency of vitamin K	0.000	0.792	0.208
E55.0 Rickets, active	0.000	0.795	0.204
E21.3 Hyperparathyroidism, unspecified	0.000	0.798	0.202
I83.1 Varicose veins of lower extremities with inflammation	0.201	0.799	0.000
E67.8 Other specified hyperalimentation	0.000	0.800	0.199
E67.3 Hypervitaminosis D	0.000	0.800	0.199
E67.2 Megavitamin-B6 syndrome	0.000	0.800	0.199
E67.1 Hypercarotenaemia	0.000	0.800	0.199
E67.0 Hypervitaminosis A	0.000	0.800	0.199
E88.9 Metabolic disorder, unspecified	0.007	0.801	0.193
E22 Hyperfunction of pituitary gland	0.000	0.802	0.198
E11.4 With neurological complications	0.000	0.803	0.197
E16.2 Hypoglycaemia, unspecified	0.000	0.803	0.197
E23.6 Other disorders of pituitary gland	0.000	0.803	0.196
K90.9 Intestinal malabsorption, unspecified	0.000	0.806	0.194
E11.9 Without complications	0.000	0.808	0.192
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.809	0.191
E23.1 Drug-induced hypopituitarism	0.000	0.809	0.191
E20 Hypoparathyroidism	0.000	0.812	0.187
E61.1 Iron deficiency	0.000	0.813	0.187
E24.8 Other Cushing's syndrome	0.000	0.814	0.186
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.814	0.186
E24.3 Ectopic ACTH syndrome	0.000	0.814	0.186
E24.2 Drug-induced Cushing's syndrome	0.000	0.814	0.186
E24.1 Nelson's syndrome	0.000	0.814	0.186
E24.0 Pituitary-dependent Cushing's disease	0.000	0.814	0.186
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.815	0.185
E55.9 Vitamin D deficiency, unspecified	0.000	0.819	0.181
E34 Other endocrine disorders	0.000	0.830	0.170
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.832	0.167
E21.4 Other specified disorders of parathyroid gland	0.000	0.832	0.167
E21.2 Other hyperparathyroidism	0.000	0.832	0.167
E25.9 Adrenogenital disorder, unspecified	0.000	0.835	0.165
E25.8 Other adrenogenital disorders	0.000	0.835	0.165
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.835	0.165
E30.9 Disorder of puberty, unspecified	0.000	0.835	0.165
E30.8 Other disorders of puberty	0.000	0.835	0.165
E30.1 Precocious puberty	0.000	0.835	0.165
E30.0 Delayed puberty	0.000	0.835	0.165
E31.9 Polyglandular dysfunction, unspecified	0.000	0.835	0.165
E31.8 Other polyglandular dysfunction	0.000	0.835	0.165
E31.1 Polyglandular hyperfunction	0.000	0.835	0.165
E31.0 Autoimmune polyglandular failure	0.000	0.835	0.165
E32.9 Disease of thymus, unspecified	0.000	0.835	0.165
E32.8 Other diseases of thymus	0.000	0.835	0.165
E32.1 Abscess of thymus	0.000	0.835	0.165
E32.0 Persistent hyperplasia of thymus	0.000	0.835	0.165
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.835	0.165
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.835	0.165
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.835	0.165
E88.3 Tumour lysis syndrome	0.008	0.839	0.153
E28.3 Primary ovarian failure	0.000	0.839	0.161
E26.9 Hyperaldosteronism, unspecified	0.000	0.840	0.160
E26.8 Other hyperaldosteronism	0.000	0.840	0.160
E26.1 Secondary hyperaldosteronism	0.000	0.840	0.160
E23.0 Hypopituitarism	0.000	0.841	0.159
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.841	0.158
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.842	0.157
E28.9 Ovarian dysfunction, unspecified	0.000	0.843	0.156
E28.8 Other ovarian dysfunction	0.000	0.843	0.156
E28.1 Androgen excess	0.000	0.843	0.156
E28.0 Oestrogen excess	0.000	0.843	0.156
E29.9 Testicular dysfunction, unspecified	0.000	0.844	0.156
E29.8 Other testicular dysfunction	0.000	0.844	0.156
E29.0 Testicular hyperfunction	0.000	0.844	0.156
E53 Deficiency of other B group vitamins	0.000	0.847	0.152
E26.0 Primary hyperaldosteronism	0.000	0.848	0.152
E83.5 Disorders of calcium metabolism	0.109	0.856	0.035
E29.1 Testicular hypofunction	0.000	0.857	0.143
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.858	0.142
E22.8 Other hyperfunction of pituitary gland	0.000	0.858	0.142
E28.2 Polycystic ovarian syndrome	0.000	0.861	0.139
E20.8 Other hypoparathyroidism	0.000	0.865	0.134
E20.1 Pseudohypoparathyroidism	0.000	0.865	0.134
E20.0 Idiopathic hypoparathyroidism	0.000	0.865	0.134
E88.1 Lipodystrophy, not elsewhere classified	0.009	0.866	0.125
E22.1 Hyperprolactinaemia	0.000	0.873	0.127
E34.5 Androgen resistance syndrome	0.000	0.878	0.122
E34.4 Constitutional tall stature	0.000	0.878	0.122
E34.3 Short stature, not elsewhere classified	0.000	0.878	0.122
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.878	0.122
E34.1 Other hypersecretion of intestinal hormones	0.000	0.878	0.122
E21.0 Primary hyperparathyroidism	0.000	0.879	0.121
E34.0 Carcinoid syndrome	0.000	0.880	0.120
E34.8 Other specified endocrine disorders	0.000	0.886	0.114
E53.1 Pyridoxine deficiency	0.000	0.890	0.109
E53.0 Riboflavin deficiency	0.000	0.890	0.109
E89.0 Postprocedural hypothyroidism	0.001	0.890	0.109
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.894	0.106
Z83.7 Family history of diseases of the digestive system	0.000	0.896	0.104
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.896	0.104
M07.3 Other psoriatic arthropathies	0.000	0.897	0.103
E22.0 Acromegaly and pituitary gigantism	0.000	0.899	0.100
J45 Asthma	0.000	0.906	0.093
Z83 Family history of other specific disorders	0.000	0.907	0.093
E20.9 Hypoparathyroidism, unspecified	0.001	0.908	0.091
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.008	0.910	0.082
E53.9 Vitamin B deficiency, unspecified	0.001	0.912	0.087
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.913	0.087
Z83.5 Family history of eye and ear disorders	0.000	0.916	0.084
E34.9 Endocrine disorder, unspecified	0.001	0.918	0.082
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.918	0.082
E80.4 Gilbert's syndrome	0.007	0.920	0.073
E66 Obesity	0.000	0.922	0.078
E04 Other non-toxic goitre	0.000	0.922	0.077
Z83.1 Family history of other infectious and parasitic diseases	0.000	0.922	0.077
M07.38 Other psoriatic arthropathies (Other)	0.000	0.926	0.074
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.926	0.074
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.926	0.074
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.926	0.074
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.926	0.074
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.926	0.074
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.926	0.074
Z83.6 Family history of diseases of the respiratory system	0.000	0.926	0.074
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.000	0.928	0.071
J45.1 Nonallergic asthma	0.000	0.933	0.067
Z83.0 Family history of human immunodeficiency virus [HIV]	0.000	0.933	0.067
E27 Other disorders of adrenal gland	0.001	0.935	0.064
J45.8 Mixed asthma	0.000	0.938	0.062
E66.0 Obesity due to excess calories	0.000	0.940	0.059
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.941	0.059
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.943	0.057
E66.1 Drug-induced obesity	0.000	0.944	0.056
E04.8 Other specified non-toxic goitre	0.000	0.944	0.056
Z83.3 Family history of diabetes mellitus	0.000	0.945	0.055
E86 Volume depletion	0.001	0.947	0.051
C85.1 B-cell lymphoma, unspecified	0.000	0.950	0.050
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.000	0.950	0.050
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.950	0.050

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations