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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

Affx-28497534
log Bayes Factor = 50.5526
Chromosome 6   position 32,629,905  (GRCh37) Explore Affx-28497534 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
Chapter VII Diseases of the eye and adnexa
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.000 1.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.000 1.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.000 1.000
M35 Other systemic involvement of connective tissue
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.001 0.999
E03 Other hypothyroidism
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
H30-H36 Disorders of choroid and retina
0.000 0.001 0.999
M20-M25 Other joint disorders
0.000 0.002 0.998
E03.9 Hypothyroidism, unspecified
0.000 0.002 0.998
E05.9 Thyrotoxicosis, unspecified
0.000 0.002 0.998
M05 Seropositive rheumatoid arthritis
0.000 0.003 0.997
H04 Disorders of lachrymal system
0.000 0.004 0.996
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.004 0.996
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.005 0.995
E10.1 With ketoacidosis
0.000 0.006 0.994
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.007 0.993
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.008 0.992
H02 Other disorders of eyelid
0.000 0.008 0.992
Chapter X Diseases of the respiratory system
0.000 0.010 0.990
N48 Other disorders of penis
0.989 0.011 0.000
J20-J22 Other acute lower respiratory infections
0.000 0.016 0.984
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.016 0.984
N40-N51 Diseases of male genital organs
0.983 0.017 0.000
N48.6 Balanitis xerotica obliterans
0.983 0.017 0.000
J22 Unspecified acute lower respiratory infection
0.000 0.020 0.980
N47 Redundant prepuce, phimosis and paraphimosis
0.979 0.021 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.000 0.023 0.977
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.024 0.976
H02.1 Ectropion of eyelid
0.000 0.025 0.975
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.026 0.974
E20-E35 Disorders of other endocrine glands
0.000 0.030 0.970
L20-L30 Dermatitis and eczema
0.000 0.036 0.964
M35.0 Sicca syndrome [Sjogren]
0.000 0.036 0.964
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.039 0.961
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.042 0.958
E27 Other disorders of adrenal gland
0.000 0.045 0.955
H02.0 Entropion and trichiasis of eyelid
0.000 0.048 0.952
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.048 0.952
N45 Orchitis and epididymitis
0.943 0.057 0.000
Chapter V Mental and behavioural disorders
0.000 0.058 0.942
J80 Adult respiratory distress syndrome
0.000 0.062 0.938
N48.0 Leukoplakia of penis
0.932 0.068 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.069 0.931
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.000 0.070 0.930
F30-F39 Mood [affective] disorders
0.000 0.071 0.929
N48.8 Other specified disorders of penis
0.925 0.075 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.075 0.925
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.081 0.919
M34 Systemic sclerosis
0.000 0.081 0.919
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.917 0.083 0.000
H04.2 Epiphora
0.000 0.085 0.915
Chapter I Certain infectious and parasitic diseases
0.000 0.089 0.911
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.093 0.907
J00-J06 Acute upper respiratory infections
0.000 0.098 0.902
D68 Other coagulation defects
0.000 0.100 0.900
F31 Bipolar affective disorder
0.000 0.104 0.896
L81 Other disorders of pigmentation
0.000 0.105 0.895
E10.5 With peripheral circulatory complications
0.000 0.105 0.895
J84 Other interstitial pulmonary diseases
0.000 0.106 0.894
B35-B49 Mycoses
0.000 0.107 0.893
B37 Candidiasis
0.000 0.110 0.890
B37.8 Candidiasis of other sites
0.000 0.111 0.889
D50-D53 Nutritional anaemias
0.000 0.115 0.885
H05 Disorders of orbit
0.000 0.115 0.885
M06.0 Seronegative rheumatoid arthritis
0.000 0.116 0.884
E06 Thyroiditis
0.000 0.119 0.881
J00 Acute nasopharyngitis [common cold]
0.000 0.119 0.881
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.127 0.873
H53-H54 Visual disturbances and blindness
0.000 0.132 0.868
L81.4 Other melanin hyperpigmentation
0.000 0.133 0.867
E10.2 With renal complications
0.000 0.134 0.866
E28 Ovarian dysfunction
0.000 0.135 0.865
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.135 0.865
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.136 0.864
L29 Pruritus
0.000 0.138 0.862
N48.9 Disorder of penis, unspecified
0.861 0.139 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.141 0.859
E11 Non-insulin-dependent diabetes mellitus
0.000 0.141 0.859
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.142 0.858
L98.8 Other specified disorders of skin and subcutaneous tissue
0.000 0.142 0.858
L98.4 Chronic ulcer of skin, not elsewhere classified
0.000 0.143 0.857
J95-J99 Other diseases of the respiratory system
0.000 0.144 0.856
F32 Depressive episode
0.000 0.144 0.856
L30 Other dermatitis
0.000 0.149 0.851
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.000 0.152 0.848
E11.3 With ophthalmic complications
0.000 0.153 0.847
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.155 0.845
E10.4 With neurological complications
0.000 0.156 0.844
M31 Other necrotising vasculopathies
0.000 0.157 0.843
M60-M63 Disorders of muscles
0.000 0.161 0.839
N48.4 Impotence of organic origin
0.839 0.161 0.000
L27 Dermatitis due to substances taken internally
0.000 0.164 0.836
B37.0 Candidal stomatitis
0.000 0.164 0.836
E70-E90 Metabolic disorders
0.000 0.165 0.835
H04.8 Other disorders of lachrymal system
0.000 0.166 0.834
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.167 0.833
M34.9 Systemic sclerosis, unspecified
0.000 0.167 0.833
M06.3 Rheumatoid nodule
0.000 0.169 0.831
L57.0 Actinic keratosis
0.000 0.172 0.828
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.827 0.173 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.000 0.178 0.822
C44 Other malignant neoplasms of skin
0.000 0.182 0.818
N41 Inflammatory diseases of prostate
0.818 0.182 0.000
L98.0 Pyogenic granuloma
0.000 0.186 0.814
E27.8 Other specified disorders of adrenal gland
0.000 0.189 0.811
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.000 0.190 0.810
C44.3 Skin of other and unspecified parts of face
0.000 0.191 0.809
C44.7 Skin of lower limb, including hip
0.000 0.194 0.806
H53 Visual disturbances
0.000 0.194 0.806
D50 Iron deficiency anaemia
0.000 0.194 0.806
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.195 0.804
F32.2 Severe depressive episode without psychotic symptoms
0.000 0.196 0.804
D68.5 Primary Thrombophilia
0.000 0.197 0.803
E06.3 Autoimmune thyroiditis
0.000 0.199 0.801
A63.0 Anogenital (venereal) warts
0.000 0.204 0.796
L93 Lupus erythematosus
0.000 0.205 0.795
L83 Acanthosis nigricans
0.000 0.205 0.795
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.000 0.208 0.792
F32.1 Moderate depressive episode
0.000 0.212 0.788
L85 Other epidermal thickening
0.000 0.213 0.787
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.214 0.786
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.218 0.782
L08 Other local infections of skin and subcutaneous tissue
0.000 0.219 0.781
D68.9 Coagulation defect, unspecified
0.000 0.219 0.781
H55-H59 Other disorders of eye and adnexa
0.000 0.220 0.780
E20 Hypoparathyroidism
0.000 0.221 0.779
E04 Other non-toxic goitre
0.000 0.221 0.779
D68.0 Von Willebrand's disease
0.000 0.223 0.777
F31.9 Bipolar affective disorder, unspecified
0.000 0.224 0.776
L29.0 Pruritus ani
0.000 0.225 0.775
N48.5 Ulcer of penis
0.773 0.226 0.000
H53.9 Visual disturbance, unspecified
0.000 0.227 0.773
E10.8 With unspecified complications
0.000 0.227 0.773
D68.8 Other specified coagulation defects
0.000 0.229 0.771
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.000 0.230 0.770
C44.6 Skin of upper limb, including shoulder
0.000 0.230 0.770
N44 Torsion of testis
0.770 0.230 0.000
F30 Manic episode
0.000 0.232 0.768
H05.0 Acute inflammation of orbit
0.000 0.233 0.767
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.233 0.767
D50.8 Other iron deficiency anaemias
0.000 0.235 0.765
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.000 0.238 0.762
E29 Testicular dysfunction
0.000 0.238 0.762
E28.2 Polycystic ovarian syndrome
0.000 0.240 0.760
H04.3 Acute and unspecified inflammation of lachrymal passages
0.000 0.242 0.757
F80-F89 Disorders of psychological development
0.000 0.244 0.756
M35.7 Hypermobility syndrome
0.000 0.245 0.755
L94 Other localised connective tissue disorders
0.000 0.249 0.751
J20 Acute bronchitis
0.000 0.250 0.750
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.251 0.749
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.252 0.748
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.253 0.747
H04.4 Chronic inflammation of lachrymal passages
0.000 0.253 0.746
F31.0 Bipolar affective disorder, current episode hypomanic
0.000 0.254 0.746
L30.9 Dermatitis, unspecified
0.000 0.254 0.746
M34.1 CR(E)ST syndrome
0.000 0.254 0.745
H02.4 Ptosis of eyelid
0.000 0.256 0.744
E27.9 Disorder of adrenal gland, unspecified
0.000 0.256 0.744
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.257 0.743
M31.3 Wegener's granulomatosis
0.000 0.257 0.743
D60-D64 Aplastic and other anaemias
0.000 0.258 0.742
L80 Vitiligo
0.000 0.258 0.742
C44.1 Skin of eyelid, including canthus
0.000 0.260 0.740
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.262 0.738
E11.1 With ketoacidosis
0.000 0.263 0.737
C44.0 Skin of lip
0.000 0.264 0.736
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.265 0.735
H02.6 Xanthelasma of eyelid
0.000 0.266 0.734
M21 Other acquired deformities of limbs
0.000 0.268 0.732
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.268 0.732
M62 Other disorders of muscle
0.000 0.268 0.732
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.275 0.725
L20 Atopic dermatitis
0.000 0.277 0.723
H02.9 Disorder of eyelid, unspecified
0.000 0.277 0.723
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.278 0.722
E89.0 Postprocedural hypothyroidism
0.000 0.278 0.722
H05.2 Exophthalmic conditions
0.000 0.279 0.721
E07 Other disorders of thyroid
0.000 0.279 0.721
H53.0 Amblyopia ex anopsia
0.000 0.279 0.721
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.000 0.281 0.719
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.281 0.719
D52 Folate deficiency anaemia
0.000 0.282 0.718
J81 Pulmonary oedema
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
M12 Other specific arthropathies
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
F39 Unspecified mood [affective] disorder
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.283 0.717
M35.8 Other specified systemic involvement of connective tissue
0.000 0.283 0.717
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.283 0.717
M35.5 Multifocal fibrosclerosis
0.000 0.283 0.717
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.283 0.717
M35.2 Behcet's disease
0.000 0.283 0.717
M35.1 Other overlap syndromes
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.284 0.716
E03.4 Atrophy of thyroid (acquired)
0.000 0.284 0.716
E03.3 Postinfectious hypothyroidism
0.000 0.284 0.716
E03.1 Congenital hypothyroidism without goitre
0.000 0.284 0.716
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.284 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
H30 Chorioretinal inflammation
0.000 0.284 0.716
L30.8 Other specified dermatitis
0.000 0.284 0.716
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.284 0.716
M32 Systemic lupus erythematosus
0.000 0.284 0.716
M05.8 Other seropositive rheumatoid arthritis
0.000 0.285 0.715
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.285 0.715
M05.2 Rheumatoid vasculitis
0.000 0.285 0.715
M05.1 Rheumatoid lung disease
0.000 0.285 0.715
M05.0 Felty's syndrome
0.000 0.285 0.715
H04.9 Disorder of lachrymal system, unspecified
0.000 0.285 0.715
H04.6 Other changes in lachrymal passages
0.000 0.286 0.714
H04.0 Dacryoadenitis
0.000 0.286 0.714
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.286 0.713
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.286 0.713
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.286 0.713
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.286 0.713
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.286 0.713
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.286 0.713
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.286 0.713
J01 Acute sinusitis
0.000 0.287 0.713
D68.6 Other Thrombophilia
0.000 0.287 0.713
N49.2 Inflammatory disorders of scrotum
0.712 0.288 0.000
E10.6 With other specified complications
0.000 0.288 0.711
F34 Persistent mood [affective] disorders
0.000 0.289 0.711
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.289 0.711
H02.7 Other degenerative disorders of eyelid and periocular area
0.000 0.289 0.711
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.289 0.711
L82 Seborrhoeic keratosis
0.000 0.290 0.710
M06.34 Rheumatoid nodule (Hand)
0.000 0.290 0.710
N48.3 Priapism
0.709 0.291 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.291 0.709
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.293 0.707
F00-F09 Organic, including symptomatic, mental disorders
0.000 0.294 0.706
M07 Psoriatic and enteropathic arthropathies
0.000 0.295 0.705
N51 Disorders of male genital organs in diseases classified elsewhere
0.705 0.295 0.000
B25-B34 Other viral diseases
0.000 0.296 0.704
N48.2 Other inflammatory disorders of penis
0.703 0.297 0.000
J21 Acute bronchiolitis
0.000 0.298 0.702
N50 Other disorders of male genital organs
0.702 0.298 0.000
F20 Schizophrenia
0.000 0.301 0.699
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.304 0.696
E32 Diseases of thymus
0.000 0.304 0.696
E31 Polyglandular dysfunction
0.000 0.304 0.696
E30 Disorders of puberty, not elsewhere classified
0.000 0.304 0.696
L57.4 Cutis laxa senilis
0.000 0.305 0.695
D61 Other aplastic anaemias
0.000 0.306 0.694
E27.2 Addisonian crisis
0.000 0.308 0.692
L25 Unspecified contact dermatitis
0.000 0.308 0.691
L24 Irritant contact dermatitis
0.000 0.308 0.691
L21 Seborrhoeic dermatitis
0.000 0.308 0.691
L26 Exfoliative dermatitis
0.000 0.308 0.691
L22 Diaper [napkin] dermatitis
0.000 0.308 0.691
E28.3 Primary ovarian failure
0.000 0.309 0.690
M06.4 Inflammatory polyarthropathy
0.000 0.310 0.690
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.311 0.689
L87 Transepidermal elimination disorders
0.000 0.311 0.689
L88 Pyoderma gangrenosum
0.000 0.311 0.689
L86 Keratoderma in diseases classified elsewhere
0.000 0.311 0.689
F22 Persistent delusional disorders
0.000 0.311 0.688
M21.0 Valgus deformity, not elsewhere classified
0.000 0.313 0.687
E27.5 Adrenomedullary hyperfunction
0.000 0.315 0.684
E27.0 Other adrenocortical overactivity
0.000 0.315 0.684
H01 Other inflammation of eyelid
0.000 0.317 0.683
J04 Acute laryngitis and tracheitis
0.000 0.317 0.683
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.317 0.683
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.317 0.683
L58 Radiodermatitis
0.000 0.317 0.683
L55 Sunburn
0.000 0.317 0.683
H02.2 Lagophthalmos
0.000 0.318 0.682
N41.9 Inflammatory disease of prostate, unspecified
0.681 0.319 0.000
E05.8 Other thyrotoxicosis
0.000 0.320 0.680
J98 Other respiratory disorders
0.000 0.321 0.679
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.322 0.678
H03 Disorders of eyelid in diseases classified elsewhere
0.000 0.322 0.678
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.323 0.677
L93.0 Discoid lupus erythematosus
0.000 0.323 0.677
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.000 0.324 0.676
N48.1 Balanoposthitis
0.674 0.326 0.000
H55 Nystagmus and other irregular eye movements
0.000 0.327 0.673
F32.3 Severe depressive episode with psychotic symptoms
0.000 0.327 0.673
N41.0 Acute prostatitis
0.673 0.327 0.000
M62.8 Other specified disorders of muscle
0.000 0.328 0.672
L23 Allergic contact dermatitis
0.000 0.329 0.670
L29.9 Pruritus, unspecified
0.000 0.331 0.669
E65-E68 Obesity and other hyperalimentation
0.000 0.332 0.668
F23 Acute and transient psychotic disorders
0.000 0.333 0.667
L98.7 Excessive and redundant skin and subcutaneous tissue
0.000 0.333 0.667
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.000 0.333 0.667
L98.5 Mucinosis of skin
0.000 0.333 0.667
L98.3 Eosinophilic cellulitis [Wells]
0.000 0.333 0.667
L98.1 Factitial dermatitis
0.000 0.333 0.667
F38 Other mood [affective] disorders
0.000 0.333 0.666
E14 Unspecified diabetes mellitus
0.000 0.334 0.666
D69 Purpura and other haemorrhagic conditions
0.000 0.334 0.666
B07 Viral warts
0.000 0.334 0.666
M00-M03 Infectious arthropathies
0.000 0.335 0.665
H02.8 Other specified disorders of eyelid
0.000 0.335 0.665
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.337 0.663
L57.5 Actinic granuloma
0.000 0.337 0.663
L57.3 Poikiloderma of Civatte
0.000 0.337 0.663
L57.2 Cutis rhomboidalis nuchae
0.000 0.337 0.663
L57.1 Actinic reticuloid
0.000 0.337 0.663
D51 Vitamin B12 deficiency anaemia
0.000 0.338 0.661
D61.9 Aplastic anaemia, unspecified
0.000 0.339 0.661
E26 Hyperaldosteronism
0.000 0.340 0.659
F70-F79 Mental retardation
0.000 0.341 0.659
D67 Hereditary factor IX deficiency
0.000 0.341 0.659
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.341 0.659
M34.8 Other forms of systemic sclerosis
0.000 0.341 0.659
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.341 0.659
M34.0 Progressive systemic sclerosis
0.000 0.341 0.659
J84.8 Other specified interstitial pulmonary diseases
0.000 0.342 0.657
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.343 0.657
E73 Lactose intolerance
0.000 0.343 0.657
N42 Other disorders of prostate
0.657 0.343 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.344 0.656
C44.4 Skin of scalp and neck
0.000 0.346 0.654
E04.2 Non-toxic multinodular goitre
0.000 0.346 0.654
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.346 0.653
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.346 0.653
A75-A79 Rickettsioses
0.000 0.346 0.653
A70-A74 Other diseases caused by chlamydiae
0.000 0.346 0.653
A20-A28 Certain zoonotic bacterial diseases
0.000 0.346 0.653
H33 Retinal detachments and breaks
0.000 0.347 0.653
E04.0 Non-toxic diffuse goitre
0.000 0.348 0.652
E11.2 With renal complications
0.000 0.348 0.652
E23 Hypofunction and other disorders of pituitary gland
0.000 0.349 0.651
C44.2 Skin of ear and external auricular canal
0.000 0.349 0.651
L01 Impetigo
0.000 0.350 0.650
L00 Staphylococcal scalded skin syndrome
0.000 0.350 0.650
E88 Other metabolic disorders
0.000 0.350 0.650
H35 Other retinal disorders
0.000 0.350 0.650
N46 Male infertility
0.650 0.350 0.000
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.351 0.649
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.647 0.353 0.000
B65-B83 Helminthiases
0.000 0.353 0.647
E03.8 Other specified hypothyroidism
0.000 0.353 0.647
E86 Volume depletion
0.000 0.354 0.646
E22 Hyperfunction of pituitary gland
0.000 0.355 0.645
L28 Lichen simplex chronicus and prurigo
0.000 0.355 0.645
D68.4 Acquired coagulation factor deficiency
0.000 0.355 0.645
D68.1 Hereditary factor XI deficiency
0.000 0.355 0.645
J95.0 Tracheostomy malfunction
0.000 0.355 0.645
M11 Other crystal arthropathies
0.000 0.356 0.644
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.000 0.357 0.643
H06.2 Dysthyroid exophthalmos
0.000 0.357 0.643
F31.8 Other bipolar affective disorders
0.000 0.358 0.642
F31.7 Bipolar affective disorder, currently in remission
0.000 0.358 0.642
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.000 0.358 0.642
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.000 0.358 0.642
L81.7 Pigmented purpuric dermatosis
0.000 0.358 0.642
L81.6 Other disorders of diminished melanin formation
0.000 0.358 0.642
L81.5 Leukoderma, not elsewhere classified
0.000 0.358 0.642
L81.3 Cafe au lait spots
0.000 0.358 0.642
L81.2 Freckles
0.000 0.358 0.642
L81.1 Chloasma
0.000 0.358 0.642
L81.0 Postinflammatory hyperpigmentation
0.000 0.358 0.642
E20.9 Hypoparathyroidism, unspecified
0.000 0.358 0.642
J84.0 Alveolar and parietoalveolar conditions
0.000 0.359 0.641
A65-A69 Other spirochaetal diseases
0.000 0.360 0.640
B48 Other mycoses, not elsewhere classified
0.000 0.360 0.640
B47 Mycetoma
0.000 0.360 0.640
B46 Zygomycosis
0.000 0.360 0.640
B45 Cryptococcosis
0.000 0.360 0.640
B43 Chromomycosis and phaeomycotic abscess
0.000 0.360 0.640
B42 Sporotrichosis
0.000 0.360 0.640
B41 Paracoccidioidomycosis
0.000 0.360 0.640
B40 Blastomycosis
0.000 0.360 0.640
B39 Histoplasmosis
0.000 0.360 0.640
B38 Coccidioidomycosis
0.000 0.360 0.640
L29.2 Pruritus vulvae
0.000 0.360 0.640
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.000 0.361 0.639
B37.7 Candidal septicaemia
0.000 0.362 0.638
B37.6 Candidal endocarditis
0.000 0.362 0.638
B37.5 Candidal meningitis
0.000 0.362 0.638
B37.1 Pulmonary candidiasis
0.000 0.362 0.638
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.362 0.638
F25 Schizoaffective disorders
0.000 0.363 0.637
B37.2 Candidiasis of skin and nail
0.000 0.363 0.636
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.000 0.364 0.636
M30 Polyarteritis nodosa and related conditions
0.000 0.364 0.636
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.365 0.635
E34 Other endocrine disorders
0.000 0.365 0.635
H05.9 Disorder of orbit, unspecified
0.000 0.366 0.634
H05.5 Retained (old) foreign body following penetrating wound of orbit
0.000 0.366 0.634
H05.4 Enophthalmos
0.000 0.366 0.634
H05.3 Deformity of orbit
0.000 0.366 0.634
H05.1 Chronic inflammatory disorders of orbit
0.000 0.366 0.634
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.366 0.634
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.366 0.634
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.366 0.634
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.366 0.634
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.366 0.634
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.366 0.634
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.366 0.634
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.366 0.634
F30.0 Hypomania
0.000 0.367 0.633
E06.5 Other chronic thyroiditis
0.000 0.368 0.632
E06.4 Drug-induced thyroiditis
0.000 0.368 0.632
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.368 0.632
E06.1 Subacute thyroiditis
0.000 0.368 0.632
E06.0 Acute thyroiditis
0.000 0.368 0.632
M14 Arthropathies in other diseases classified elsewhere
0.000 0.368 0.632
L81.8 Other specified disorders of pigmentation
0.000 0.368 0.632
M22 Disorders of patella
0.000 0.368 0.632
M86-M90 Other osteopathies
0.000 0.370 0.630
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.371 0.629
M33 Dermatopolymyositis
0.000 0.372 0.628
E50-E64 Other nutritional deficiencies
0.000 0.372 0.627
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.000 0.374 0.626
J95.8 Other postprocedural respiratory disorders
0.000 0.374 0.626
L10-L14 Bullous disorders
0.000 0.374 0.626
H04.1 Other disorders of lachrymal gland
0.000 0.374 0.625
B50-B64 Protozoal diseases
0.000 0.375 0.625
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.376 0.624
L85.8 Other specified epidermal thickening
0.000 0.376 0.624
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.379 0.621
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.379 0.621
E28.9 Ovarian dysfunction, unspecified
0.000 0.379 0.620
E28.8 Other ovarian dysfunction
0.000 0.379 0.620
E28.1 Androgen excess
0.000 0.379 0.620
E28.0 Oestrogen excess
0.000 0.379 0.620
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.380 0.620
E06.9 Thyroiditis, unspecified
0.000 0.381 0.619
H33.2 Serous retinal detachment
0.000 0.381 0.619
L29.3 Anogenital pruritus, unspecified
0.000 0.382 0.618
L29.1 Pruritus scroti
0.000 0.382 0.618
E74 Other disorders of carbohydrate metabolism
0.000 0.382 0.618
D55-D59 Haemolytic anaemias
0.000 0.383 0.617
L85.9 Epidermal thickening, unspecified
0.000 0.383 0.617
E11.7 With multiple complications
0.000 0.384 0.616
A59 Trichomoniasis
0.000 0.385 0.615
A56 Other sexually transmitted chlamydial diseases
0.000 0.385 0.615
A54 Gonococcal infection
0.000 0.385 0.615
A53 Other and unspecified syphilis
0.000 0.385 0.615
A52 Late syphilis
0.000 0.385 0.615
A51 Early syphilis
0.000 0.385 0.615
A50 Congenital syphilis
0.000 0.385 0.615
A64 Unspecified sexually transmitted disease
0.000 0.385 0.615
A58 Granuloma inguinale
0.000 0.385 0.615
A57 Chancroid
0.000 0.385 0.615
A55 Chlamydial lymphogranuloma (venereum)
0.000 0.385 0.615
B35 Dermatophytosis
0.000 0.385 0.615
H02.5 Other disorders affecting eyelid function
0.000 0.385 0.615
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.000 0.386 0.614
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.000 0.386 0.614
J96 Respiratory failure, not elsewhere classified
0.000 0.386 0.614
H05.8 Other disorders of orbit
0.000 0.386 0.613
M65-M68 Disorders of synovium and tendon
0.000 0.388 0.612
E29.1 Testicular hypofunction
0.000 0.388 0.612
M24 Other specific joint derangements
0.000 0.388 0.612
L30.5 Pityriasis alba
0.000 0.390 0.610
L30.4 Erythema intertrigo
0.000 0.390 0.610
L30.2 Cutaneous autosensitisation
0.000 0.390 0.610
L30.1 Dyshidrosis [pompholyx]
0.000 0.390 0.610
L30.0 Nummular dermatitis
0.000 0.390 0.610
B90-B94 Sequelae of infectious and parasitic diseases
0.000 0.390 0.610
D53 Other nutritional anaemias
0.000 0.391 0.609
D68.2 Hereditary deficiency of other clotting factors
0.000 0.391 0.609
F28 Other nonorganic psychotic disorders
0.000 0.392 0.608
F24 Induced delusional disorder
0.000 0.392 0.608
F21 Schizotypal disorder
0.000 0.392 0.608
L04 Acute lymphadenitis
0.000 0.394 0.606
H10-H13 Disorders of conjunctiva
0.000 0.395 0.605
M31.9 Necrotising vasculopathy, unspecified
0.000 0.395 0.604
M31.8 Other specified necrotising vasculopathies
0.000 0.395 0.604
M31.7 Microscopic polyangiitis
0.000 0.395 0.604
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.395 0.604
M31.2 Lethal midline granuloma
0.000 0.395 0.604

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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