TreeWAS – Variant ID: rs1003342

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E03 Other hypothyroidism	0.803	0.197	0.000
E03.8 Other specified hypothyroidism	0.682	0.318	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.647	0.353	0.000
E03.1 Congenital hypothyroidism without goitre	0.640	0.359	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.599	0.401	0.000
E03.5 Myxoedema coma	0.576	0.424	0.000
E03.4 Atrophy of thyroid (acquired)	0.576	0.424	0.000
E03.3 Postinfectious hypothyroidism	0.576	0.424	0.000
E00-E07 Disorders of thyroid gland	0.207	0.793	0.000
E06 Thyroiditis	0.185	0.815	0.000
E06.3 Autoimmune thyroiditis	0.165	0.835	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.159	0.841	0.000
E07 Other disorders of thyroid	0.155	0.845	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.149	0.851	0.000
E00 Congenital iodine-deficiency syndrome	0.149	0.851	0.000
E06.5 Other chronic thyroiditis	0.139	0.861	0.000
E06.9 Thyroiditis, unspecified	0.138	0.862	0.000
E06.4 Drug-induced thyroiditis	0.133	0.867	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.133	0.867	0.000
E06.1 Subacute thyroiditis	0.133	0.867	0.000
E06.0 Acute thyroiditis	0.133	0.867	0.000
E07.9 Disorder of thyroid, unspecified	0.131	0.869	0.000
E07.1 Dyshormogenetic goitre	0.111	0.888	0.000
E07.0 Hypersecretion of calcitonin	0.111	0.888	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.107	0.893	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.107	0.893	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.107	0.893	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.107	0.893	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.107	0.893	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.107	0.893	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.107	0.893	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.107	0.893	0.000
E07.8 Other specified disorders of thyroid	0.088	0.912	0.000
S22.40 Multiple fractures of ribs (closed)	0.066	0.934	0.000
E04 Other non-toxic goitre	0.052	0.948	0.000
E10 Insulin-dependent diabetes mellitus	0.049	0.951	0.000
E10.3 With ophthalmic complications	0.049	0.951	0.000
E10.1 With ketoacidosis	0.049	0.951	0.000
E10.2 With renal complications	0.046	0.954	0.000
E10.4 With neurological complications	0.044	0.956	0.000
E10.9 Without complications	0.038	0.962	0.000
E04.8 Other specified non-toxic goitre	0.037	0.962	0.000
E10.7 With multiple complications	0.037	0.963	0.000
E04.9 Non-toxic goitre, unspecified	0.037	0.963	0.000
E10.8 With unspecified complications	0.034	0.966	0.000
E10.6 With other specified complications	0.034	0.966	0.000
S22.4 Multiple fractures of ribs	0.032	0.968	0.000
E10.5 With peripheral circulatory complications	0.031	0.969	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.030	0.970	0.000
E04.0 Non-toxic diffuse goitre	0.029	0.970	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.972	0.028
H83.0 Labyrinthitis	0.027	0.973	0.000
E10.0 With coma	0.024	0.975	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.976	0.024
S22.41 Multiple fractures of ribs (open)	0.023	0.977	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.023	0.977	0.000
E05.5 Thyroid crisis or storm	0.022	0.978	0.000
E05.4 Thyrotoxicosis factitia	0.022	0.978	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.022	0.978	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.022	0.978	0.000
E04.2 Non-toxic multinodular goitre	0.022	0.978	0.000
I80 Phlebitis and thrombophlebitis	0.000	0.979	0.021
E10-E14 Diabetes mellitus	0.019	0.981	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.017	0.983	0.000
E05.8 Other thyrotoxicosis	0.017	0.983	0.000
E04.1 Non-toxic single thyroid nodule	0.016	0.984	0.000
S80.9 Superficial injury of lower leg, unspecified	0.016	0.984	0.000
S82.40 Fracture of fibula alone (closed)	0.016	0.984	0.000
D50.8 Other iron deficiency anaemias	0.015	0.985	0.000
S82.4 Fracture of fibula alone	0.014	0.986	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.986	0.014
E12 Malnutrition-related diabetes mellitus	0.014	0.986	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.000	0.986	0.014
S82 Fracture of lower leg, including ankle	0.014	0.986	0.000
S82.2 Fracture of shaft of tibia	0.013	0.987	0.000
S82.20 Fracture of shaft of tibia (closed)	0.013	0.987	0.000
S82.7 Multiple fractures of lower leg	0.013	0.987	0.000
S82.70 Multiple fractures of lower leg (closed)	0.012	0.988	0.000
Z45.2 Adjustment and management of vascular access device	0.012	0.988	0.000
S82.0 Fracture of patella	0.012	0.988	0.000
S82.6 Fracture of lateral malleolus	0.012	0.988	0.000
S82.9 Fracture of lower leg, part unspecified	0.011	0.989	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.989	0.011
S82.21 Fracture of shaft of tibia (open)	0.011	0.989	0.000
S82.01 Fracture of patella (open)	0.011	0.989	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.011	0.989	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.011	0.989	0.000
E13 Other specified diabetes mellitus	0.011	0.989	0.000
S82.41 Fracture of fibula alone (open)	0.010	0.989	0.000
E12.9 Without complications	0.010	0.990	0.000
E12.8 With unspecified complications	0.010	0.990	0.000
E12.7 With multiple complications	0.010	0.990	0.000
E12.6 With other specified complications	0.010	0.990	0.000
E12.5 With peripheral circulatory complications	0.010	0.990	0.000
E12.4 With neurological complications	0.010	0.990	0.000
E12.3 With ophthalmic complications	0.010	0.990	0.000
E12.2 With renal complications	0.010	0.990	0.000
E12.1 With ketoacidosis	0.010	0.990	0.000
E12.0 With coma	0.010	0.990	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.990	0.010
S80 Superficial injury of lower leg	0.010	0.990	0.000
E14 Unspecified diabetes mellitus	0.010	0.990	0.000
S82.60 Fracture of lateral malleolus (closed)	0.010	0.990	0.000
H83 Other diseases of inner ear	0.010	0.990	0.000
S80-S89 Injuries to the knee and lower leg	0.010	0.990	0.000
S81 Open wound of lower leg	0.010	0.990	0.000
S81.8 Open wound of other parts of lower leg	0.009	0.991	0.000
S82.71 Multiple fractures of lower leg (open)	0.009	0.991	0.000
S82.61 Fracture of lateral malleolus (open)	0.009	0.991	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.009	0.991	0.000
E14.2 Withrenal complications	0.009	0.991	0.000
E40-E46 Malnutrition	0.009	0.991	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.009	0.991	0.000
S82.5 Fracture of medial malleolus	0.009	0.991	0.000
Y40.0 Penicillins	0.009	0.991	0.000
N18.5 Chronic kidney disease, stage 5	0.009	0.991	0.000
S81.7 Multiple open wounds of lower leg	0.009	0.991	0.000
E14.1 With ketoacidosis	0.009	0.991	0.000
S81.9 Open wound of lower leg, part unspecified	0.008	0.992	0.000
E15 Nondiabetic hypoglycaemic coma	0.008	0.992	0.000
E14.0 With coma	0.008	0.992	0.000
E13.3 With ophthalmic complications	0.008	0.992	0.000
E13.8 With unspecified complications	0.008	0.992	0.000
E13.7 With multiple complications	0.008	0.992	0.000
E13.6 With other specified complications	0.008	0.992	0.000
E13.5 With peripheral circulatory complications	0.008	0.992	0.000
E13.4 With neurological complications	0.008	0.992	0.000
E13.2 With renal complications	0.008	0.992	0.000
E13.1 With ketoacidosis	0.008	0.992	0.000
E13.0 With coma	0.008	0.992	0.000
E50-E64 Other nutritional deficiencies	0.008	0.992	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.008	0.992	0.000
E14.5 With peripheral circulatory complications	0.008	0.992	0.000
H83.2 Labyrinthine dysfunction	0.007	0.992	0.000
E14.7 With multiple complications	0.007	0.993	0.000
S87 Crushing injury of lower leg	0.007	0.993	0.000
H83.1 Labyrinthine fistula	0.007	0.993	0.000
S88 Traumatic amputation of lower leg	0.007	0.993	0.000
S85 Injury of blood vessels at lower leg level	0.007	0.993	0.000
S84 Injury of nerves at lower leg level	0.007	0.993	0.000
H83.8 Other specified diseases of inner ear	0.007	0.993	0.000
S82.00 Fracture of patella (closed)	0.007	0.993	0.000
H83.9 Disease of inner ear, unspecified	0.007	0.993	0.000
E14.6 With other specified complications	0.007	0.993	0.000
E89.0 Postprocedural hypothyroidism	0.007	0.993	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.007	0.993	0.000
E45 Retarded development following protein-energy malnutrition	0.007	0.993	0.000
E43 Unspecified severe protein-energy malnutrition	0.007	0.993	0.000
E42 Marasmic kwashiorkor	0.007	0.993	0.000
E41 Nutritional marasmus	0.007	0.993	0.000
E40 Kwashiorkor	0.007	0.993	0.000
S80.0 Contusion of knee	0.007	0.993	0.000
E14.8 With unspecified complications	0.007	0.993	0.000
E65-E68 Obesity and other hyperalimentation	0.007	0.993	0.000
E14.4 With neurological complications	0.006	0.993	0.000
S80.7 Multiple superficial injuries of lower leg	0.006	0.993	0.000
Z49.1 Extracorporeal dialysis	0.006	0.994	0.000
S82.51 Fracture of medial malleolus (open)	0.006	0.994	0.000
S89 Other and unspecified injuries of lower leg	0.006	0.994	0.000
H83.3 Noise effects on inner ear	0.006	0.994	0.000
S82.8 Fractures of other parts of lower leg	0.006	0.994	0.000
F03 Unspecified dementia	0.006	0.994	0.000
E16 Other disorders of pancreatic internal secretion	0.006	0.994	0.000
E51 Thiamine deficiency	0.006	0.994	0.000
S86 Injury of muscle and tendon at lower leg level	0.006	0.994	0.000
E63 Other nutritional deficiencies	0.006	0.994	0.000
E56 Other vitamin deficiencies	0.006	0.994	0.000
E58 Dietary calcium deficiency	0.006	0.994	0.000
S82.1 Fracture of upper end of tibia	0.006	0.994	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.006	0.994	0.000
E50 Vitamin A deficiency	0.006	0.994	0.000
E60 Dietary zinc deficiency	0.006	0.994	0.000
E59 Dietary selenium deficiency	0.006	0.994	0.000
E54 Ascorbic acid deficiency	0.006	0.994	0.000
E52 Niacin deficiency [pellagra]	0.006	0.994	0.000
S22.9 Fracture of bony thorax, part unspecified	0.006	0.994	0.000
S22.8 Fracture of other parts of bony thorax	0.006	0.994	0.000
H44.2 Degenerative myopia	0.006	0.994	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.994	0.006
S87.8 Crushing injury of other and unspecified parts of lower leg	0.006	0.994	0.000
E55 Vitamin D deficiency	0.006	0.994	0.000
S80.8 Other superficial injuries of lower leg	0.006	0.994	0.000
S82.50 Fracture of medial malleolus (closed)	0.006	0.994	0.000
M41.9 Scoliosis, unspecified	0.006	0.994	0.000
S87.0 Crushing injury of knee	0.005	0.994	0.000
B37.8 Candidiasis of other sites	0.006	0.994	0.000
S82.3 Fracture of lower end of tibia	0.005	0.994	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.005	0.994	0.000
S84.8 Injury of other nerves at lower leg level	0.005	0.994	0.000
S84.7 Injury of multiple nerves at lower leg level	0.005	0.994	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.005	0.994	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.005	0.994	0.000
S84.0 Injury of tibial nerve at lower leg level	0.005	0.994	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.005	0.994	0.000
S85.8 Injury of other blood vessels at lower leg level	0.005	0.994	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.005	0.994	0.000
S85.5 Injury of popliteal vein	0.005	0.994	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.005	0.994	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.005	0.994	0.000
S85.2 Injury of peroneal artery	0.005	0.994	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.005	0.994	0.000
S85.0 Injury of popliteal artery	0.005	0.994	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.005	0.994	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.005	0.994	0.000
S88.0 Traumatic amputation at knee level	0.005	0.994	0.000
S22.5 Flail chest	0.005	0.995	0.000
L90.0 Lichen sclerosus et atrophicus	0.000	0.995	0.005
S22.1 Multiple fractures of thoracic spine	0.005	0.995	0.000
S22.0 Fracture of thoracic vertebra	0.005	0.995	0.000
S22.3 Fracture of rib	0.005	0.995	0.000
E44.1 Mild protein-energy malnutrition	0.005	0.995	0.000
E44.0 Moderate protein-energy malnutrition	0.005	0.995	0.000
E16.1 Other hypoglycaemia	0.005	0.995	0.000
R52.1 Chronic intractable pain	0.005	0.995	0.000
H44 Disorders of globe	0.005	0.995	0.000
N02.8 Other	0.005	0.995	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.005	0.995	0.000
E67 Other hyperalimentation	0.005	0.995	0.000
E68 Sequelae of hyperalimentation	0.005	0.995	0.000
S22.2 Fracture of sternum	0.005	0.995	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.005	0.995	0.000
E51.2 Wernicke's encephalopathy	0.005	0.995	0.000
H44.0 Purulent endophthalmitis	0.005	0.995	0.000
H44.4 Hypotony of eye	0.005	0.995	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.005	0.995	0.000
S89.8 Other specified injuries of lower leg	0.005	0.995	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.005	0.995	0.000
S89.7 Multiple injuries of lower leg	0.005	0.995	0.000
S89.1 Other specified injuries of lower leg	0.005	0.995	0.000
S89.0 Multiple injuries of lower leg	0.005	0.995	0.000
C77.1 Intrathoracic lymph nodes	0.005	0.995	0.000
E56.1 Deficiency of vitamin K	0.005	0.995	0.000
E63.9 Nutritional deficiency, unspecified	0.005	0.995	0.000
S82.86 Maisonneuve's fracture	0.005	0.995	0.000
E51.9 Thiamine deficiency, unspecified	0.005	0.995	0.000
E51.8 Other manifestations of thiamine deficiency	0.005	0.995	0.000
E51.1 Beriberi	0.005	0.995	0.000
K25.7 Chronic without haemorrhage or perforation	0.005	0.995	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.005	0.995	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.005	0.995	0.000
E16.4 Abnormal secretion of gastrin	0.005	0.995	0.000
E16.3 Increased secretion of glucagon	0.005	0.995	0.000
S86.0 Injury of Achilles tendon	0.005	0.995	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.005	0.995	0.000
E56.9 Vitamin deficiency, unspecified	0.004	0.995	0.000
E56.8 Deficiency of other vitamins	0.004	0.995	0.000
E56.0 Deficiency of vitamin E	0.004	0.995	0.000
E63.8 Other specified nutritional deficiencies	0.004	0.995	0.000
E63.1 Imbalance of constituents of food intake	0.004	0.995	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.004	0.995	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.005	0.995	0.000
E14.3 With ophthalmic complications	0.005	0.995	0.000
E50.9 Vitamin A deficiency, unspecified	0.004	0.995	0.000
E50.8 Other manifestations of vitamin A deficiency	0.004	0.995	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.004	0.995	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.004	0.995	0.000
E50.5 Vitamin A deficiency with night blindness	0.004	0.995	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.004	0.995	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.004	0.995	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.004	0.995	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.004	0.995	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.004	0.995	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.004	0.995	0.000
E64.8 Sequelae of other nutritional deficiencies	0.004	0.995	0.000
E64.3 Sequelae of rickets	0.004	0.995	0.000
E64.2 Sequelae of vitamin C deficiency	0.004	0.995	0.000
E64.1 Sequelae of vitamin A deficiency	0.004	0.995	0.000
E64.0 Sequelae of protein-energy malnutrition	0.004	0.995	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.004	0.995	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.004	0.996	0.000
S22.80 Fracture of other parts of bony thorax (closed)	0.004	0.996	0.000
S22.91 Fracture of bony thorax, part unspecified (open)	0.004	0.996	0.000
S22.90 Fracture of bony thorax, part unspecified (closed)	0.004	0.996	0.000
H44.8 Other disorders of globe	0.004	0.996	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.004	0.996	0.000
E13.9 Without complications	0.004	0.996	0.000
Z99.2 Dependence on renal dialysis	0.004	0.996	0.000
E55.0 Rickets, active	0.004	0.996	0.000
Z99.8 Dependence on other enabling machines and devices	0.004	0.996	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.004	0.996	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.004	0.996	0.000
N18.0 End-stage renal disease	0.004	0.996	0.000
S22.51 Flail chest (open)	0.004	0.996	0.000
Z99.3 Dependence on wheelchair	0.004	0.996	0.000
H44.5 Degenerated conditions of globe	0.004	0.996	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.004	0.996	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.004	0.996	0.000
E55.9 Vitamin D deficiency, unspecified	0.004	0.996	0.000
J31.0 Chronic rhinitis	0.000	0.996	0.004
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.004	0.996	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.004	0.996	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.004	0.996	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.004	0.996	0.000
E65 Localised adiposity	0.004	0.996	0.000
S22.01 Fracture of thoracic vertebra (open)	0.004	0.996	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.004	0.996	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.004	0.996	0.000
S22.31 Fracture of rib (open)	0.004	0.996	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.004	0.996	0.000
H44.6 Retained (old) intraocular foreign body, magnetic	0.004	0.996	0.000
H44.3 Other degenerative disorders of globe	0.004	0.996	0.000
E67.8 Other specified hyperalimentation	0.004	0.996	0.000
E67.3 Hypervitaminosis D	0.004	0.996	0.000
E67.2 Megavitamin-B6 syndrome	0.004	0.996	0.000
E67.1 Hypercarotenaemia	0.004	0.996	0.000
E67.0 Hypervitaminosis A	0.004	0.996	0.000
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.004	0.996	0.000
S22.21 Fracture of sternum (open)	0.004	0.996	0.000
E53 Deficiency of other B group vitamins	0.004	0.996	0.000
S22.50 Flail chest (closed)	0.004	0.996	0.000
S82.81 Fractures of other parts of lower leg (open)	0.004	0.996	0.000
S82.11 Fracture of upper end of tibia (open)	0.003	0.996	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.004	0.996	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.003	0.996	0.000
S86.00 Unspecified injury of Achilles tendon	0.003	0.996	0.000
S89.9 Unspecified injury of lower leg	0.004	0.996	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.004	0.996	0.000
Q61.3 Polycystic kidney, unspecified	0.000	0.996	0.004
M21.3 Wrist or foot drop (acquired)	0.000	0.996	0.003
S14.3 Injury of brachial plexus	0.003	0.996	0.000
H44.9 Disorder of globe, unspecified	0.003	0.997	0.000
E85.9 Amyloidosis, unspecified	0.003	0.997	0.000
H44.1 Other endophthalmitis	0.003	0.997	0.000
I12.9 Hypertensive renal disease without renal failure	0.003	0.997	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.003	0.997	0.000
S14.1 Other and unspecified injuries of cervical spinal cord	0.003	0.997	0.000
C85.1 B-cell lymphoma, unspecified	0.003	0.997	0.000
E46 Unspecified protein-energy malnutrition	0.003	0.997	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.003	0.997	0.000
H61.8 Other specified disorders of external ear	0.000	0.997	0.003
C22.1 Intrahepatic bile duct carcinoma	0.000	0.997	0.003
J35.1 Hypertrophy of tonsils	0.003	0.997	0.000
E61 Deficiency of other nutrient elements	0.003	0.997	0.000
S22.30 Fracture of rib (closed)	0.003	0.997	0.000
E89.2 Postprocedural hypoparathyroidism	0.003	0.997	0.000
R76.8 Other specified abnormal immunological findings in serum	0.000	0.997	0.003
N18.8 Other chronic renal failure	0.003	0.997	0.000
Y77.3 Surgical instruments, materials and devices (including sutures)	0.003	0.997	0.000
Z99.4 Dependence on artificial heart	0.003	0.997	0.000
Z99.0 Dependence on aspirator	0.003	0.997	0.000
N18 Chronic renal failure	0.003	0.997	0.000
S14 Injury of nerves and spinal cord at neck level	0.003	0.997	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.003	0.997	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.000	0.997	0.003
Z99.9 Dependence on unspecified enabling machine and device	0.003	0.997	0.000
M41 Scoliosis	0.003	0.997	0.000
E89.1 Postprocedural hypoinsulinaemia	0.003	0.997	0.000
E53.1 Pyridoxine deficiency	0.003	0.997	0.000
E53.0 Riboflavin deficiency	0.003	0.997	0.000
M79.18 Myalgia (Other)	0.003	0.997	0.000
S81.0 Open wound of knee	0.003	0.997	0.000
S22.20 Fracture of sternum (closed)	0.003	0.997	0.000
B25.9 Cytomegaloviral disease, unspecified	0.003	0.997	0.000
Z94.0 Kidney transplant status	0.003	0.997	0.000
S82.31 Fracture of lower end of tibia (open)	0.003	0.997	0.000
B34.9 Viral infection, unspecified	0.003	0.997	0.000
E85 Amyloidosis	0.003	0.997	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.003	0.997	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.003	0.997	0.000
E89.5 Postprocedural testicular hypofunction	0.003	0.997	0.000
Y77 Ophthalmic devices associated with adverse incidents	0.003	0.997	0.000
Q61 Cystic kidney disease	0.000	0.997	0.003
Z49 Care involving dialysis	0.003	0.997	0.000
Y76.2 Prosthetic and other implants, materials and accessory devices	0.003	0.997	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.000	0.997	0.003
M21.38 Wrist or foot drop (acquired)-Other	0.000	0.997	0.003
M21.36 Wrist or foot drop (acquired)-Lower leg	0.000	0.997	0.003
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.000	0.997	0.003
M21.34 Wrist or foot drop (acquired) (Hand)	0.000	0.997	0.003
M21.32 Wrist or foot drop (acquired)-Upper arm	0.000	0.997	0.003
M21.31 Wrist or foot drop (acquired)-Shldr region	0.000	0.997	0.003
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.000	0.997	0.003
S82.80 Fractures of other parts of lower leg (closed)	0.003	0.997	0.000
K25.4 Chronic or unspecified with haemorrhage	0.003	0.997	0.000
Z99.1 Dependence on respirator	0.003	0.997	0.000
K25 Gastric ulcer	0.003	0.997	0.000
T14.0 Superficial injury of unspecified body region	0.003	0.997	0.000
D50 Iron deficiency anaemia	0.003	0.997	0.000
M41.8 Other forms of scoliosis	0.003	0.997	0.000
M41.2 Other idiopathic scoliosis	0.003	0.997	0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents	0.003	0.997	0.000
E61.9 Deficiency of nutrient element, unspecified	0.002	0.997	0.000
E61.8 Deficiency of other specified nutrient elements	0.002	0.997	0.000
E61.7 Deficiency of multiple nutrient elements	0.002	0.997	0.000
E61.6 Vanadium deficiency	0.002	0.997	0.000
E61.5 Molybdenum deficiency	0.002	0.997	0.000
E61.4 Chromium deficiency	0.002	0.997	0.000
E61.3 Manganese deficiency	0.002	0.997	0.000
E61.0 Copper deficiency	0.002	0.997	0.000
E53.9 Vitamin B deficiency, unspecified	0.002	0.997	0.000
Q61.2 Polycystic kidney, adult type	0.000	0.997	0.003
M41.4 Neuromuscular scoliosis	0.002	0.997	0.000
Q61.0 Congenital single renal cyst	0.000	0.997	0.003
M21.33 Wrist or foot drop (acquired) (Forearm)	0.000	0.997	0.002
S14.6 Injury of other and unspecified nerves of neck	0.002	0.997	0.000
S14.5 Injury of cervical sympathetic nerves	0.002	0.997	0.000
S14.4 Injury of peripheral nerves of neck	0.002	0.997	0.000
S14.2 Injury of nerve root of cervical spine	0.002	0.997	0.000
S14.0 Concussion and oedema of cervical spinal cord	0.002	0.997	0.000
B34 Viral infection of unspecified site	0.003	0.997	0.000
E85.8 Other amyloidosis	0.002	0.997	0.000
B25 Cytomegaloviral disease	0.003	0.997	0.000
M41.3 Thoracogenic scoliosis	0.002	0.997	0.000
M41.1 Juvenile idiopathic scoliosis	0.002	0.997	0.000
M41.0 Infantile idiopathic scoliosis	0.002	0.997	0.000
Z49.2 Other dialysis	0.002	0.997	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.003	0.997	0.000
B34.8 Other viral infections of unspecified site	0.002	0.997	0.000
N41.0 Acute prostatitis	0.000	0.997	0.003
E89.3 Postprocedural hypopituitarism	0.002	0.997	0.000
K25.0 Acute with haemorrhage	0.002	0.998	0.000
R76.0 Raised antibody titer	0.000	0.998	0.002
S82.10 Fracture of upper end of tibia (closed)	0.002	0.998	0.000
M41.80 Other forms of scoliosis (Multiple sites in spine)	0.002	0.998	0.000
K25.5 Chronic or unspecified with perforation	0.002	0.998	0.000
Y77.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
M41.85 Other forms of scoliosis (Thoracolumbar region)	0.002	0.998	0.000
Y82 Other and unspecified medical devices associated with adverse incidents	0.002	0.998	0.000
S82.30 Fracture of lower end of tibia (closed)	0.002	0.998	0.000
E70-E90 Metabolic disorders	0.002	0.998	0.000
E85.3 Secondary systemic amyloidosis	0.002	0.998	0.000
K25.1 Acute with perforation	0.002	0.998	0.000
Q61.5 Medullary cystic kidney	0.000	0.998	0.002
E85.2 Heredofamilial amyloidosis, unspecified	0.002	0.998	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.002	0.998	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.002	0.998	0.000
Q61.9 Cystic kidney disease, unspecified	0.000	0.998	0.002
M41.29 Other idiopathic scoliosis (Site unspecified)	0.002	0.998	0.000
M41.5 Other secondary scoliosis	0.002	0.998	0.000
H66.9 Otitis media, unspecified	0.002	0.998	0.000
N18.1 Chronic kidney disease, stage 1	0.002	0.998	0.000
Q61.8 Other cystic kidney diseases	0.000	0.998	0.002
Q61.1 Polycystic kidney, infantile type	0.000	0.998	0.002
Y77.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y77.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
Y77.0 Diagnostic and monitoring devices	0.002	0.998	0.000
N02 Recurrent and persistent haematuria	0.002	0.998	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
Y82.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
Y81 General- and plastic-surgery devices associated with adverse incidents	0.002	0.998	0.000
B25.0 Cytomegaloviral pneumonitis	0.002	0.998	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.002	0.998	0.000
K25.6 Chronic or unspecified with both haemorrhage and perforation	0.002	0.998	0.000
K25.2 Acute with both haemorrhage and perforation	0.002	0.998	0.000
N18.4 Chronic kidney disease, stage 4	0.002	0.998	0.000
Q61.4 Renal dysplasia	0.000	0.998	0.002
R76 Other abnormal immunological findings in serum	0.000	0.998	0.002
B34.3 Parvovirus infection, unspecified	0.002	0.998	0.000
D50.1 Sideropenic dysphagia	0.002	0.998	0.000
H66.3 Other chronic suppurative otitis media	0.002	0.998	0.000
E89.4 Postprocedural ovarian failure	0.002	0.998	0.000
B25.8 Other cytomegaloviral diseases	0.002	0.998	0.000
M41.28 Other idiopathic scoliosis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M41.27 Other idiopathic scoliosis (Lumbosacral region)	0.002	0.998	0.000
M41.26 Other idiopathic scoliosis (Lumbar region)	0.002	0.998	0.000
M41.25 Other idiopathic scoliosis (Thoracolumbar region)	0.002	0.998	0.000
M41.24 Other idiopathic scoliosis (Thoracic region)	0.002	0.998	0.000
M41.23 Other idiopathic scoliosis (Cervicothoracic region)	0.002	0.998	0.000
M41.22 Other idiopathic scoliosis (Cervical region)	0.002	0.998	0.000
M41.21 Other idiopathic scoliosis (Occipito-atlanto-axial region)	0.002	0.998	0.000
M41.20 Other idiopathic scoliosis (Multiple sites in spine)	0.002	0.998	0.000
M41.89 Other forms of scoliosis (Site unspecified)	0.002	0.998	0.000
M41.88 Other forms of scoliosis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M41.87 Other forms of scoliosis (Lumbosacral region)	0.002	0.998	0.000
M41.84 Other forms of scoliosis (Thoracic region)	0.002	0.998	0.000
M41.83 Other forms of scoliosis (Cervicothoracic region)	0.002	0.998	0.000
M41.82 Other forms of scoliosis (Cervical region)	0.002	0.998	0.000
M41.81 Other forms of scoliosis (Occipito-atlanto-axial region)	0.002	0.998	0.000
N90.5 Atrophy of vulva	0.000	0.998	0.002
M41.49 Neuromuscular scoliosis (Site unspecified)	0.002	0.998	0.000
M21 Other acquired deformities of limbs	0.000	0.998	0.002
Y71 Cardiovascular devices associated with adverse incidents	0.002	0.998	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.002	0.998	0.000
Y76.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y76.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
Y76.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
Y76.0 Diagnostic and monitoring devices	0.002	0.998	0.000
Y81.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
E85.4 Organ-limited amyloidosis	0.002	0.998	0.000
E77 Disorders of glycoprotein metabolism	0.002	0.998	0.000
M41.48 Neuromuscular scoliosis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M41.47 Neuromuscular scoliosis (Lumbosacral region)	0.002	0.998	0.000
M41.46 Neuromuscular scoliosis (Lumbar region)	0.002	0.998	0.000
M41.45 Neuromuscular scoliosis (Thoracolumbar region)	0.002	0.998	0.000
M41.44 Neuromuscular scoliosis (Thoracic region)	0.002	0.998	0.000
M41.43 Neuromuscular scoliosis (Cervicothoracic region)	0.002	0.998	0.000
M41.42 Neuromuscular scoliosis (Cervical region)	0.002	0.998	0.000
M41.41 Neuromuscular scoliosis (Occipito-atlanto-axial region)	0.002	0.998	0.000
M41.40 Neuromuscular scoliosis (Multiple sites in spine)	0.002	0.998	0.000
E05.9 Thyrotoxicosis, unspecified	0.002	0.998	0.000
D16.4 Bones of skull and face	0.002	0.998	0.000
M79.1 Myalgia	0.002	0.998	0.000
B25.2 Cytomegaloviral pancreatitis	0.002	0.998	0.000
B25.1 Cytomegaloviral hepatitis	0.002	0.998	0.000
B34.2 Coronavirus infection, unspecified	0.002	0.998	0.000
B34.1 Enterovirus infection, unspecified	0.002	0.998	0.000
B34.0 Adenovirus infection, unspecified	0.002	0.998	0.000
C22.9 Liver, unspecified	0.000	0.998	0.002
E70 Disorders of aromatic amino-acid metabolism	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations