TreeWAS – Variant ID: rs10039217

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
M47.8 Other spondylosis	0.035	0.965
M47.82 Other spondylosis (Cervical region)	0.035	0.965
M47 Spondylosis	0.034	0.966
M45-M49 Spondylopathies	0.033	0.967
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.031	0.969
M20-M25 Other joint disorders	0.030	0.970
M47.86 Other spondylosis (Lumbar region)	0.030	0.970
M23 Internal derangement of knee	0.029	0.971
M47.89 Other spondylosis (Site unspecified)	0.027	0.972
M45 Ankylosing spondylitis	0.027	0.973
M15-M19 Arthrosis	0.027	0.973
M46 Other inflammatory spondylopathies	0.026	0.974
M47.9 Spondylosis, unspecified	0.026	0.974
M23.2 Derangement of meniscus due to old tear or injury	0.026	0.974
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.025	0.975
M47.85 Other spondylosis (Thoracolumbar region)	0.025	0.975
M47.84 Other spondylosis (Thoracic region)	0.025	0.975
M47.83 Other spondylosis (Cervicothoracic region)	0.025	0.975
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.025	0.975
M47.80 Other spondylosis (Multiple sites in spine)	0.025	0.975
M17 Gonarthrosis [arthrosis of knee]	0.025	0.975
M86-M90 Other osteopathies	0.025	0.975
M21 Other acquired deformities of limbs	0.025	0.975
M25 Other joint disorders, not elsewhere classified	0.025	0.975
M47.2 Other spondylosis with radiculopathy	0.024	0.975
M47.1 Other spondylosis with myelopathy	0.024	0.975
M47.0 Anterior spinal and vertebral artery compression syndromes	0.024	0.975
M23.8 Other internal derangements of knee	0.024	0.976
M47.87 Other spondylosis (Lumbosacral region)	0.024	0.976
M24 Other specific joint derangements	0.024	0.976
M49 Spondylopathies in diseases classified elsewhere	0.024	0.976
M48 Other spondylopathies	0.024	0.976
M34 Systemic sclerosis	0.023	0.976
M50-M54 Other dorsopathies	0.023	0.977
M17.9 Gonarthrosis, unspecified	0.023	0.977
M80-M85 Disorders of bone density and structure	0.023	0.977
M40-M43 Deforming dorsopathies	0.023	0.977
M45.X9 Ankylosing spondylitis (Site unspecified)	0.023	0.977
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.023	0.977
M22 Disorders of patella	0.022	0.978
M91-M94 Chondropathies	0.022	0.978
M60-M63 Disorders of muscles	0.022	0.978
M00-M03 Infectious arthropathies	0.022	0.978
M25.7 Osteophyte	0.022	0.978
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.022	0.978
M33 Dermatopolymyositis	0.022	0.978
M32 Systemic lupus erythematosus	0.022	0.978
M31 Other necrotising vasculopathies	0.022	0.978
M30 Polyarteritis nodosa and related conditions	0.022	0.978
M46.9 Inflammatory spondylopathy, unspecified	0.022	0.978
M23.3 Other meniscus derangements	0.022	0.978
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.022	0.978
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.021	0.979
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.021	0.979
M19 Other arthrosis	0.021	0.979
M18 Arthrosis of first carpometacarpal joint	0.021	0.979
M65-M68 Disorders of synovium and tendon	0.021	0.979
M23.9 Internal derangement of knee, unspecified	0.021	0.979
M23.6 Other spontaneous disruption of ligament(s) of knee	0.021	0.979
M23.5 Chronic instability of knee	0.021	0.979
M23.4 Loose body in knee	0.021	0.979
M23.1 Discoid meniscus (congenital)	0.021	0.979
M23.0 Cystic meniscus	0.021	0.979
M21.1 Varus deformity, not elsewhere classified	0.021	0.979
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.021	0.979
M17.0 Primary gonarthrosis, bilateral	0.021	0.979
M47.96 Spondylosis, unspecified (Lumbar region)	0.020	0.980
M35 Other systemic involvement of connective tissue	0.020	0.980
M89 Other disorders of bone	0.020	0.980
M70-M79 Other soft tissue disorders	0.020	0.980
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.020	0.980
M25.8 Other specified joint disorders	0.020	0.980
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.020	0.980
M25.4 Effusion of joint	0.020	0.980
M24.0 Loose body in joint	0.020	0.980
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.020	0.980
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.020	0.980
M45.X6 Ankylosing spondylitis (Lumbar region)	0.020	0.980
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.020	0.980
M45.X4 Ankylosing spondylitis (Thoracic region)	0.020	0.980
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.020	0.980
M45.X2 Ankylosing spondylitis (Cervical region)	0.020	0.980
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.020	0.980
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.020	0.980
M47.92 Spondylosis, unspecified (Cervical region)	0.019	0.980
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.019	0.981
M15 Polyarthrosis	0.019	0.981
M46.8 Other specified inflammatory spondylopathies	0.019	0.981
M46.5 Other infective spondylopathies	0.019	0.981
M46.4 Discitis, unspecified	0.019	0.981
M46.3 Infection of intervertebral disk (pyogenic)	0.019	0.981
M46.2 Osteomyelitis of vertebra	0.019	0.981
M46.1 Sacro-iliitis, not elsewhere classified	0.019	0.981
M46.0 Spinal enthesopathy	0.019	0.981
M50 Cervical disk disorders	0.019	0.981
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.019	0.981
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.019	0.981
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.019	0.981
M47.94 Spondylosis, unspecified (Thoracic region)	0.019	0.981
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.019	0.981
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.019	0.981
M84 Disorders of continuity of bone	0.019	0.981
M25.77 Osteophyte (Ankle and foot)	0.019	0.981
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.019	0.981
M87 Osteonecrosis	0.019	0.981
M34.9 Systemic sclerosis, unspecified	0.019	0.981
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.018	0.981
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.018	0.981
D64.9 Anaemia, unspecified	0.018	0.982
M17.5 Other secondary gonarthrosis	0.018	0.982
M17.4 Other secondary gonarthrosis, bilateral	0.018	0.982
M17.3 Other posttraumatic gonarthrosis	0.018	0.982
M17.2 Posttraumatic gonarthrosis, bilateral	0.018	0.982
M21.3 Wrist or foot drop (acquired)	0.018	0.982
M47.99 Spondylosis, unspecified (Site unspecified)	0.018	0.982
M90 Osteopathies in diseases classified elsewhere	0.018	0.982
M88 Paget's disease of bone [osteitis deformans]	0.018	0.982
M86 Osteomyelitis	0.018	0.982
M25.75 Osteophyte (Pelvic region and thigh)	0.018	0.982
M21.9 Acquired deformity of limb, unspecified	0.018	0.982
M21.8 Other specified acquired deformities of limbs	0.018	0.982
M21.7 Unequal limb length (acquired)	0.018	0.982
M21.6 Other acquired deformities of ankle and foot	0.018	0.982
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.018	0.982
M21.4 Flat foot [pes planus] (acquired)	0.018	0.982
M21.2 Flexion deformity	0.018	0.982
M21.0 Valgus deformity, not elsewhere classified	0.018	0.982
M05-M14 Inflammatory polyarthropathies	0.018	0.982
M25.9 Joint disorder, unspecified	0.018	0.982
M25.6 Stiffness of joint, not elsewhere classified	0.018	0.982
M25.3 Other instability of joint	0.018	0.982
M25.2 Flail joint	0.018	0.982
M25.1 Fistula of joint	0.018	0.982
M25.0 Haemarthrosis	0.018	0.982
M41 Scoliosis	0.018	0.982
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.018	0.982
M47.09 Anterior spinal and vertebral artery compression syndromes (Site unspecified)	0.018	0.982
M47.08 Anterior spinal and vertebral artery compression syndromes (Sacral and sacrococcygeal region)	0.018	0.982
M47.07 Anterior spinal and vertebral artery compression syndromes (Lumbosacral region)	0.018	0.982
M47.06 Anterior spinal and vertebral artery compression syndromes (Lumbar region)	0.018	0.982
M47.05 Anterior spinal and vertebral artery compression syndromes (Thoracolumbar region)	0.018	0.982
M47.04 Anterior spinal and vertebral artery compression syndromes (Thoracic region)	0.018	0.982
M47.03 Anterior spinal and vertebral artery compression syndromes (Cervicothoracic region)	0.018	0.982
M47.02 Anterior spinal and vertebral artery compression syndromes (Cervical region)	0.018	0.982
M47.01 Anterior spinal and vertebral artery compression syndromes (Occipito-atlanto-axial region)	0.018	0.982
M47.00 Anterior spinal and vertebral artery compression syndromes (Multiple sites in spine)	0.018	0.982
M47.19 Other spondylosis with myelopathy (Site unspecified)	0.018	0.982
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)	0.018	0.982
M47.17 Other spondylosis with myelopathy (Lumbosacral region)	0.018	0.982
M47.16 Other spondylosis with myelopathy (Lumbar region)	0.018	0.982
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)	0.018	0.982
M47.14 Other spondylosis with myelopathy (Thoracic region)	0.018	0.982
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)	0.018	0.982
M47.12 Other spondylosis with myelopathy (Cervical region)	0.018	0.982
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)	0.018	0.982
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)	0.018	0.982
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.018	0.982
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.018	0.982
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.018	0.982
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.018	0.982
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.018	0.982
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.018	0.982
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.018	0.982
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.018	0.982
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.018	0.982
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.018	0.982
M80 Osteoporosis with pathological fracture	0.018	0.982
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.018	0.982
M79 Other soft tissue disorders, not elsewhere classified	0.018	0.982
M23.87 Other internal derangements of knee (Capsular ligament)	0.018	0.982
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.018	0.982
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.018	0.982
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.018	0.982
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.018	0.982
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.018	0.982
M23.80 Other internal derangements of knee (Multiple sites)	0.018	0.982
M24.1 Other articular cartilage disorders	0.017	0.982
M24.9 Joint derangement, unspecified	0.017	0.982
M24.8 Other specific joint derangements, not elsewhere classified	0.017	0.982
M24.7 Protrusio acetabuli	0.017	0.982
M24.6 Ankylosis of joint	0.017	0.982
M24.5 Contracture of joint	0.017	0.982
M24.4 Recurrent dislocation and subluxation of joint	0.017	0.982
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.017	0.982
M24.2 Disorder of ligament	0.017	0.982
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.018	0.982
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.017	0.982
M17.1 Other primary gonarthrosis	0.017	0.983
M19.97 Arthrosis, unspecified (Ankle and foot)	0.017	0.983
M49.8 Spondylopathy in other diseases classified elsewhere	0.017	0.983
M49.5 Collapsed vertebra in diseases classified elsewhere	0.017	0.983
M49.4 Neuropathic spondylopathy	0.017	0.983
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.017	0.983
M49.2 Enterobacterial spondylitis	0.017	0.983
M49.1 Brucella spondylitis	0.017	0.983
M49.0 Tuberculosis of spine	0.017	0.983
M25.76 Osteophyte (Lower leg)	0.017	0.983
M48.9 Spondylopathy, unspecified	0.017	0.983
M48.8 Other specified spondylopathies	0.017	0.983
M48.5 Collapsed vertebra, not elsewhere classified	0.017	0.983
M48.4 Fatigue fracture of vertebra	0.017	0.983
M48.3 Traumatic spondylopathy	0.017	0.983
M48.2 Kissing spine	0.017	0.983
M48.1 Ankylosing hyperostosis [Forestier]	0.017	0.983
M22.2 Patellofemoral disorders	0.017	0.983
M34.8 Other forms of systemic sclerosis	0.017	0.983
M34.2 Systemic sclerosis induced by drugs and chemicals	0.017	0.983
M34.1 CR(E)ST syndrome	0.017	0.983
M34.0 Progressive systemic sclerosis	0.017	0.983
M53 Other dorsopathies, not elsewhere classified	0.017	0.983
M19.9 Arthrosis, unspecified	0.017	0.983
M48.0 Spinal stenosis	0.017	0.983
M20 Acquired deformities of fingers and toes	0.017	0.983
M51 Other intervertebral disk disorders	0.017	0.983
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.017	0.983
M43 Other deforming dorsopathies	0.017	0.983
M85 Other disorders of bone density and structure	0.017	0.983
M83 Adult osteomalacia	0.017	0.983
M82 Osteoporosis in diseases classified elsewhere	0.017	0.983
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.017	0.983
M42 Spinal osteochondrosis	0.017	0.983
M40 Kyphosis and lordosis	0.017	0.983
M89.9 Disorder of bone, unspecified	0.017	0.983
M24.07 Loose body in joint (Ankle and foot)	0.017	0.983
D64 Other anaemias	0.017	0.983
M99 Biomechanical lesions, not elsewhere classified	0.016	0.983
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.016	0.983
M25.46 Effusion of joint (Lower leg)	0.016	0.984
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.016	0.984
M22.1 Recurrent subluxation of patella	0.016	0.984
M22.9 Disorder of patella, unspecified	0.016	0.984
M22.8 Other disorders of patella	0.016	0.984
M22.3 Other derangements of patella	0.016	0.984
M22.0 Recurrent dislocation of patella	0.016	0.984
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.016	0.984
M02 Reactive arthropathies	0.016	0.984
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.016	0.984
M00 Pyogenic arthritis	0.016	0.984
M63 Disorders of muscle in diseases classified elsewhere	0.016	0.984
M62 Other disorders of muscle	0.016	0.984
M61 Calcification and ossification of muscle	0.016	0.984
M60 Myositis	0.016	0.984
M94 Other disorders of cartilage	0.016	0.984
M93 Other osteochondropathies	0.016	0.984
M92 Other juvenile osteochondrosis	0.016	0.984
M91 Juvenile osteochondrosis of hip and pelvis	0.016	0.984
M19.0 Primary arthrosis of other joints	0.016	0.984
M25.79 Osteophyte (Site unspecified)	0.016	0.984
M25.78 Osteophyte (Other)	0.016	0.984
M25.74 Osteophyte (Hand)	0.016	0.984
M25.73 Osteophyte (Forearm)	0.016	0.984
M25.72 Osteophyte (Upper arm)	0.016	0.984
M25.71 Osteophyte (Shoulder region)	0.016	0.984
M25.70 Osteophyte (Multiple sites)	0.016	0.984
M18.1 Other primary arthrosis of first carpometacarpal joint	0.016	0.984
M30.8 Other conditions related to polyarteritis nodosa	0.016	0.984
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.016	0.984
M30.2 Juvenile polyarteritis	0.016	0.984
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.016	0.984
M30.0 Polyarteritis nodosa	0.016	0.984
M31.9 Necrotising vasculopathy, unspecified	0.016	0.984
M31.8 Other specified necrotising vasculopathies	0.016	0.984
M31.7 Microscopic polyangiitis	0.016	0.984
M31.6 Other giant cell arteritis	0.016	0.984
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.016	0.984
M31.4 Aortic arch syndrome [Takayasu]	0.016	0.984
M31.3 Wegener's granulomatosis	0.016	0.984
M31.2 Lethal midline granuloma	0.016	0.984
M31.1 Thrombotic microangiopathy	0.016	0.984
M31.0 Hypersensitivity angiitis	0.016	0.984
M32.9 Systemic lupus erythematosus, unspecified	0.016	0.984
M32.8 Other forms of systemic lupus erythematosus	0.016	0.984
M32.1 Systemic lupus erythematosus with organ or system involvement	0.016	0.984
M32.0 Drug-induced systemic lupus erythematosus	0.016	0.984
M33.9 Dermatopolymyositis, unspecified	0.016	0.984
M33.2 Polymyositis	0.016	0.984
M33.1 Other dermatomyositis	0.016	0.984
M33.0 Juvenile dermatomyositis	0.016	0.984
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.016	0.984
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.016	0.984
M36.3 Arthropathy in other blood disorders	0.016	0.984
M36.2 Haemophilic arthropathy	0.016	0.984
M36.1 Arthropathy in neoplastic disease	0.016	0.984
M36.0 Dermato(poly)myositis in neoplastic disease	0.016	0.984
M84.1 Nonunion of fracture [pseudarthrosis]	0.016	0.984
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.016	0.984
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.016	0.984
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.016	0.984
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.016	0.984
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.016	0.984
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.016	0.984
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.016	0.984
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.016	0.984
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.016	0.984
M79.8 Other specified soft tissue disorders	0.016	0.984
M23.37 Other meniscus derangements-Capsular lig	0.016	0.984
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.016	0.984
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.016	0.984
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.016	0.984
M54 Dorsalgia	0.016	0.984
M77 Other enthesopathies	0.016	0.984
M22.4 Chondromalacia patellae	0.015	0.984
M25.84 Other specified joint disorders (Hand)	0.015	0.984
M19.8 Other specified arthrosis	0.015	0.984
M19.2 Other secondary arthrosis	0.015	0.984
M19.1 Posttraumatic arthrosis of other joints	0.015	0.984
M50.2 Other cervical disk displacement	0.015	0.984
M25.86 Other specified joint disorders (Lower leg)	0.015	0.984
D60-D64 Aplastic and other anaemias	0.016	0.984
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.015	0.984
M50.3 Other cervical disk degeneration	0.015	0.985
M23.30 Other meniscus derangements (Multiple sites)	0.015	0.985
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.015	0.985
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.015	0.985
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.015	0.985
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.015	0.985
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.015	0.985
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.015	0.985
M66 Spontaneous rupture of synovium and tendon	0.015	0.985
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.015	0.985
M23.07 Cystic meniscus-Capsular lig	0.015	0.985
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.015	0.985
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.015	0.985
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.015	0.985
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.015	0.985
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.015	0.985
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.015	0.985
M23.00 Cystic meniscus (Multiple sites)	0.015	0.985
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.015	0.985
M23.17 Discoid meniscus (congenital)-Capsular lig	0.015	0.985
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.015	0.985
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.015	0.985
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.015	0.985
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.015	0.985
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.015	0.985
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.015	0.985
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.015	0.985
M23.49 Loose body in knee-Unspec lig/men	0.015	0.985
M23.47 Loose body in knee-Capsular lig	0.015	0.985
M23.46 Loose body in knee-O/unsp lat men	0.015	0.985
M23.45 Loose body in knee-Pst hrn lat men	0.015	0.985
M23.44 Loose body in knee-Lat lig/ant men	0.015	0.985
M23.43 Loose body in knee-Med lig/oth men	0.015	0.985
M23.42 Loose body in knee-Pst lig/hrn men	0.015	0.985
M23.41 Loose body in knee-Ant lig/hrn men	0.015	0.985
M23.40 Loose body in knee-Mult sites	0.015	0.985
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.015	0.985
M23.57 Chronic instability of knee (Capsular ligament)	0.015	0.985
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.015	0.985
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.015	0.985
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.015	0.985
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.015	0.985
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.015	0.985
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.015	0.985
M23.50 Chronic instability of knee (Multiple sites)	0.015	0.985
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.015	0.985
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.015	0.985
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.015	0.985
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.015	0.985
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.015	0.985
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.015	0.985
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.015	0.985
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.015	0.985
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.015	0.985
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.015	0.985
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.015	0.985
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.015	0.985
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.015	0.985
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.015	0.985
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.015	0.985
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.015	0.985
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.015	0.985
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.015	0.985
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.015	0.985
M21.18 Varus deformity, not elsewhere classified (Other)	0.015	0.985
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.015	0.985
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.015	0.985
M21.14 Varus deformity, not elsewhere classified (Hand)	0.015	0.985
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.015	0.985
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.015	0.985
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.015	0.985
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.015	0.985
M71 Other bursopathies	0.015	0.985
M35.9 Systemic involvement of connective tissue, unspecified	0.015	0.985
M35.8 Other specified systemic involvement of connective tissue	0.015	0.985
M35.7 Hypermobility syndrome	0.015	0.985
M35.6 Relapsing panniculitis [Weber-Christian]	0.015	0.985
M35.5 Multifocal fibrosclerosis	0.015	0.985
M35.4 Diffuse (eosinophilic) fasciitis	0.015	0.985
M35.2 Behcet's disease	0.015	0.985
M35.1 Other overlap syndromes	0.015	0.985
M35.3 Polymyalgia rheumatica	0.015	0.985
M89.8 Other specified disorders of bone	0.014	0.985
M89.6 Osteopathy after poliomyelitis	0.014	0.985
M89.5 Osteolysis	0.014	0.985
M89.4 Other hypertrophic osteo-arthropathy	0.014	0.985
M89.3 Hypertrophy of bone	0.014	0.985
M89.2 Other disorders of bone development and growth	0.014	0.985
M89.1 Epiphyseal arrest	0.014	0.985
M89.0 Algoneurodystrophy	0.014	0.985
M65 Synovitis and tenosynovitis	0.014	0.985
M76 Enthesopathies of lower limb, excluding foot	0.014	0.985
M73 Soft tissue disorders in diseases classified elsewhere	0.014	0.985
M70 Soft tissue disorders related to use, overuse and pressure	0.014	0.985
M79.86 Other specified soft tissue disorders (Lower leg)	0.015	0.985
M67 Other disorders of synovium and tendon	0.014	0.985
M25.89 Other specified joint disorders (Site unspecified)	0.014	0.985
M25.88 Other specified joint disorders (Other)	0.014	0.985
M25.87 Other specified joint disorders (Ankle and foot)	0.014	0.985
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.014	0.985
M25.83 Other specified joint disorders (Forearm)	0.014	0.985
M25.82 Other specified joint disorders (Upper arm)	0.014	0.985
M25.81 Other specified joint disorders (Shoulder region)	0.014	0.985
M25.80 Other specified joint disorders (Multiple sites)	0.014	0.985
M25.49 Effusion of joint (Site unspecified)	0.014	0.985
M25.48 Effusion of joint (Other)	0.014	0.985
M25.47 Effusion of joint (Ankle and foot)	0.014	0.985
M25.45 Effusion of joint (Pelvic region and thigh)	0.014	0.985
M25.44 Effusion of joint (Hand)	0.014	0.985
M25.43 Effusion of joint (Forearm)	0.014	0.985
M25.42 Effusion of joint (Upper arm)	0.014	0.985
M25.41 Effusion of joint (Shoulder region)	0.014	0.985
M25.40 Effusion of joint (Multiple sites)	0.014	0.985
M24.09 Loose body in joint (Site unspecified)	0.014	0.986
M24.08 Loose body in joint (Other)	0.014	0.986
M24.06 Loose body in joint-Lower leg	0.014	0.986
M24.05 Loose body in joint (Pelvic region and thigh)	0.014	0.986
M24.04 Loose body in joint (Hand)	0.014	0.986
M24.03 Loose body in joint (Forearm)	0.014	0.986
M24.02 Loose body in joint (Upper arm)	0.014	0.986
M24.01 Loose body in joint (Shoulder region)	0.014	0.986
M24.00 Loose body in joint (Multiple sites)	0.014	0.986
M79.6 Pain in limb	0.014	0.986
M87.9 Osteonecrosis, unspecified	0.014	0.986
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.014	0.986
M20.5 Other deformities of toe(s) (acquired)	0.014	0.986
M81 Osteoporosis without pathological fracture	0.014	0.986
M15.9 Polyarthrosis, unspecified	0.014	0.986
M15.0 Primary generalised (osteo)arthrosis	0.014	0.986
M15.8 Other polyarthrosis	0.014	0.986
M15.4 Erosive (osteo)arthrosis	0.014	0.986
M15.3 Secondary multiple arthrosis	0.014	0.986
M15.2 Bouchard's nodes (with arthropathy)	0.014	0.986
M15.1 Heberden's nodes (with arthropathy)	0.014	0.986
M46.09 Spinal enthesopathy (Site unspecified)	0.014	0.986
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)	0.014	0.986
M46.07 Spinal enthesopathy (Lumbosacral region)	0.014	0.986
M46.06 Spinal enthesopathy (Lumbar region)	0.014	0.986
M46.05 Spinal enthesopathy (Thoracolumbar region)	0.014	0.986
M46.04 Spinal enthesopathy (Thoracic region)	0.014	0.986
M46.03 Spinal enthesopathy (Cervicothoracic region)	0.014	0.986
M46.02 Spinal enthesopathy (Cervical region)	0.014	0.986
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)	0.014	0.986
M46.00 Spinal enthesopathy (Multiple sites in spine)	0.014	0.986
M46.19 Sacroiliitis, not elsewhere classified-Site unspe	0.014	0.986
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ	0.014	0.986
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral	0.014	0.986
M46.16 Sacroiliitis, not elsewhere classified-Lumbar	0.014	0.986
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar	0.014	0.986
M46.14 Sacroiliitis, not elsewhere classified-Thoracic	0.014	0.986
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic	0.014	0.986
M46.12 Sacroiliitis, not elsewhere classified-Cervical	0.014	0.986
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl	0.014	0.986
M46.10 Sacroiliitis, not elsewhere classified-Mult site	0.014	0.986
M46.29 Osteomyelitis of vertebra (Site unspecified)	0.014	0.986
M46.28 Osteomyelitis of vertebra (Sacral and sacrococcygeal region)	0.014	0.986
M46.27 Osteomyelitis of vertebra (Lumbosacral region)	0.014	0.986
M46.26 Osteomyelitis of vertebra (Lumbar region)	0.014	0.986
M46.25 Osteomyelitis of vertebra (Thoracolumbar region)	0.014	0.986
M46.24 Osteomyelitis of vertebra (Thoracic region)	0.014	0.986
M46.23 Osteomyelitis of vertebra (Cervicothoracic region)	0.014	0.986
M46.22 Osteomyelitis of vertebra (Cervical region)	0.014	0.986
M46.21 Osteomyelitis of vertebra (Occipito-atlanto-axial region)	0.014	0.986
M46.20 Osteomyelitis of vertebra (Multiple sites in spine)	0.014	0.986
M46.39 Infection of intervertebral disc (pyogenic) (Site unspecified)	0.014	0.986
M46.38 Infection of intervertebral disc (pyogenic) (Sacral and sacrococcygeal region)	0.014	0.986
M46.37 Infection of intervertebral disc (pyogenic) (Lumbosacral region)	0.014	0.986
M46.36 Infection of intervertebral disc (pyogenic) (Lumbar region)	0.014	0.986
M46.35 Infection of intervertebral disc (pyogenic) (Thoracolumbar region)	0.014	0.986
M46.34 Infection of intervertebral disc (pyogenic) (Thoracic region)	0.014	0.986
M46.33 Infection of intervertebral disc (pyogenic) (Cervicothoracic region)	0.014	0.986
M46.32 Infection of intervertebral disc (pyogenic) (Cervical region)	0.014	0.986
M46.31 Infection of intervertebral disc (pyogenic) (Occipito-atlanto-axial region)	0.014	0.986
M46.30 Infection of intervertebral disc (pyogenic) (Multiple sites in spine)	0.014	0.986
M46.49 Discitis, unspecified (Site unspecified)	0.014	0.986
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)	0.014	0.986
M46.47 Discitis, unspecified (Lumbosacral region)	0.014	0.986
M46.46 Discitis, unspecified (Lumbar region)	0.014	0.986
M46.45 Discitis, unspecified (Thoracolumbar region)	0.014	0.986
M46.44 Discitis, unspecified (Thoracic region)	0.014	0.986
M46.43 Discitis, unspecified (Cervicothoracic region)	0.014	0.986
M46.42 Discitis, unspecified (Cervical region)	0.014	0.986
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)	0.014	0.986
M46.40 Discitis, unspecified (Multiple sites in spine)	0.014	0.986
M46.59 Other infective spondylopathies (Site unspecified)	0.014	0.986
M46.58 Other infective spondylopathies (Sacral and sacrococcygeal region)	0.014	0.986
M46.57 Other infective spondylopathies (Lumbosacral region)	0.014	0.986
M46.56 Other infective spondylopathies (Lumbar region)	0.014	0.986
M46.55 Other infective spondylopathies (Thoracolumbar region)	0.014	0.986
M46.54 Other infective spondylopathies (Thoracic region)	0.014	0.986

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations