TreeWAS – Variant ID: rs1006973

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H91.9 Hearing loss, unspecified	0.000	0.961	0.039
E05.9 Thyrotoxicosis, unspecified	0.028	0.972	0.000
H72 Perforation of tympanic membrane	0.000	0.976	0.024
H72.8 Other perforations of tympanic membrane	0.000	0.976	0.024
H91 Other hearing loss	0.000	0.977	0.023
H66 Suppurative and unspecified otitis media	0.000	0.977	0.023
N20.2 Calculus of kidney with calculus of ureter	0.023	0.977	0.000
H65-H75 Diseases of middle ear and mastoid	0.000	0.978	0.022
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.978	0.022
H72.0 Central perforation of tympanic membrane	0.000	0.978	0.022
H66.0 Acute suppurative otitis media	0.000	0.980	0.020
H72.1 Attic perforation of tympanic membrane	0.000	0.980	0.020
H66.9 Otitis media, unspecified	0.000	0.981	0.019
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.981	0.019
N21.0 Calculus in bladder	0.019	0.981	0.000
H73 Other disorders of tympanic membrane	0.000	0.981	0.019
H72.2 Other marginal perforations of tympanic membrane	0.000	0.982	0.018
H71 Cholesteatoma of middle ear	0.000	0.982	0.018
H70 Mastoiditis and related conditions	0.000	0.982	0.018
H90-H95 Other disorders of ear	0.000	0.982	0.018
M54.39 Sciatica (Site unspecified)	0.017	0.983	0.000
H91.2 Sudden idiopathic hearing loss	0.000	0.983	0.017
H91.0 Ototoxic hearing loss	0.000	0.983	0.017
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.000	0.983	0.017
H68 Eustachian salpingitis and obstruction	0.000	0.983	0.017
H91.3 Deaf mutism, not elsewhere classified	0.000	0.983	0.017
H90 Conductive and sensorineural hearing loss	0.000	0.983	0.017
H69 Other disorders of Eustachian tube	0.000	0.983	0.017
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.984	0.016
H67 Otitis media in diseases classified elsewhere	0.000	0.984	0.016
H66.4 Suppurative otitis media, unspecified	0.000	0.984	0.016
H70.1 Chronic mastoiditis	0.000	0.984	0.016
H73.8 Other specified disorders of tympanic membrane	0.000	0.984	0.016
H66.3 Other chronic suppurative otitis media	0.000	0.985	0.015
H91.1 Presbycusis	0.000	0.985	0.015
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.000	0.986	0.014
H73.1 Chronic myringitis	0.000	0.986	0.014
Chapter VIII Diseases of the ear and mastoid process	0.000	0.986	0.014
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.986	0.014
H73.0 Acute myringitis	0.000	0.986	0.014
N21 Calculus of lower urinary tract	0.013	0.986	0.000
H69.9 Eustachian tube disorder, unspecified	0.000	0.987	0.013
H90.2 Conductive hearing loss, unspecified	0.000	0.987	0.013
H70.0 Acute mastoiditis	0.000	0.987	0.013
H68.1 Obstruction of Eustachian tube	0.000	0.987	0.013
N20 Calculus of kidney and ureter	0.013	0.987	0.000
H70.2 Petrositis	0.000	0.987	0.013
H94 Other disorders of ear in diseases classified elsewhere	0.000	0.987	0.013
H90.0 Conductive hearing loss, bilateral	0.000	0.987	0.013
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.987	0.013
H70.8 Other mastoiditis and related conditions	0.000	0.987	0.012
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.987	0.012
H68.0 Eustachian salpingitis	0.000	0.988	0.012
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.988	0.012
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.000	0.988	0.012
H91.8 Other specified hearing loss	0.000	0.988	0.012
H69.0 Patulous Eustachian tube	0.000	0.988	0.012
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.988	0.012
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.988	0.012
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.988	0.012
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.988	0.012
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.988	0.012
N20.9 Urinary calculus, unspecified	0.012	0.988	0.000
N20-N23 Urolithiasis	0.012	0.988	0.000
H90.3 Sensorineural hearing loss, bilateral	0.000	0.989	0.011
H69.8 Other specified disorders of Eustachian tube	0.000	0.989	0.011
H70.9 Mastoiditis, unspecified	0.000	0.990	0.010
H93 Other disorders of ear, not elsewhere classified	0.000	0.990	0.010
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.000	0.990	0.010
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.000	0.990	0.010
N21.9 Calculus of lower urinary tract, unspecified	0.010	0.990	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.000	0.990	0.009
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.000	0.990	0.009
H74 Other disorders of middle ear and mastoid	0.000	0.991	0.009
N21.8 Other lower urinary tract calculus	0.008	0.991	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.008	0.991	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.000	0.992	0.008
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.992	0.008
N21.1 Calculus in urethra	0.008	0.992	0.000
H92 Otalgia and effusion of ear	0.000	0.992	0.008
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.992	0.008
H93.0 Degenerative and vascular disorders of ear	0.000	0.992	0.008
N23 Unspecified renal colic	0.008	0.992	0.000
H93.1 Tinnitus	0.000	0.992	0.008
H93.3 Disorders of acoustic nerve	0.000	0.992	0.007
H74.4 Polyp of middle ear	0.000	0.992	0.007
M50.3 Other cervical disk degeneration	0.000	0.993	0.007
H93.2 Other abnormal auditory perceptions	0.000	0.993	0.007
N92.6 Irregular menstruation, unspecified	0.007	0.993	0.000
H93.8 Other specified disorders of ear	0.000	0.993	0.007
M31.6 Other giant cell arteritis	0.007	0.993	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.993	0.007
H93.9 Disorder of ear, unspecified	0.000	0.993	0.007
N22.8 Calculus of urinary tract in other diseases classified elsewhere	0.006	0.994	0.000
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]	0.006	0.994	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.994	0.006
H92.2 Otorrhagia	0.000	0.994	0.006
J69.0 Pneumonitis due to food and vomit	0.000	0.994	0.006
T17.2 Foreign body in pharynx	0.000	0.994	0.006
H74.1 Adhesive middle ear disease	0.000	0.994	0.006
I46.0 Cardiac arrest with successful resuscitation	0.000	0.994	0.006
H65 Nonsuppurative otitis media	0.000	0.994	0.006
H74.0 Tympanosclerosis	0.000	0.994	0.005
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.995	0.005
H90.5 Sensorineural hearing loss, unspecified	0.000	0.995	0.005
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.995	0.005
R47.8 Other and unspecified speech disturbances	0.005	0.995	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.995	0.005
T17 Foreign body in respiratory tract	0.000	0.995	0.005
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.995	0.005
T17.9 Foreign body in respiratory tract, part unspecified	0.000	0.995	0.005
T17.5 Foreign body in bronchus	0.000	0.995	0.005
H95.1 Other disorders following mastoidectomy	0.001	0.995	0.004
Z97.5 Presence of (intra-uterine) contraceptive device	0.005	0.995	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.005	0.995	0.000
H92.1 Otorrhoea	0.000	0.995	0.005
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.995	0.004
H65.1 Other acute nonsuppurative otitis media	0.000	0.996	0.004
J93.1 Other spontaneous pneumothorax	0.000	0.996	0.004
D32.0 Cerebral meninges	0.000	0.996	0.004
H65.4 Other chronic nonsuppurative otitis media	0.000	0.996	0.004
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.996	0.004
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.996	0.004
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.996	0.004
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.996	0.004
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.996	0.004
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.996	0.004
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.996	0.004
E10.4 With neurological complications	0.004	0.996	0.000
T17.4 Foreign body in trachea	0.000	0.996	0.004
T17.1 Foreign body in nostril	0.000	0.996	0.004
T17.0 Foreign body in nasal sinus	0.000	0.996	0.004
T17.8 Foreign body in other and multiple parts of respiratory tract	0.000	0.996	0.004
H60-H62 Diseases of external ear	0.000	0.996	0.004
A09.9 Gastroenteritis and colitis of unspecified origin	0.004	0.996	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.004	0.996	0.000
E05.5 Thyroid crisis or storm	0.004	0.996	0.000
E05.4 Thyrotoxicosis factitia	0.004	0.996	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.004	0.996	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.996	0.004
H65.2 Chronic serous otitis media	0.000	0.996	0.003
E10 Insulin-dependent diabetes mellitus	0.004	0.996	0.000
M31 Other necrotising vasculopathies	0.004	0.996	0.000
E05.8 Other thyrotoxicosis	0.003	0.996	0.000
E10.5 With peripheral circulatory complications	0.003	0.997	0.000
E10.3 With ophthalmic complications	0.003	0.997	0.000
T17.3 Foreign body in larynx	0.000	0.997	0.003
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.997	0.003
H65.0 Acute serous otitis media	0.000	0.997	0.003
Z97.4 Presence of external hearing-aid	0.003	0.997	0.000
J02.9 Acute pharyngitis, unspecified	0.003	0.997	0.000
E10.0 With coma	0.003	0.997	0.000
M31.8 Other specified necrotising vasculopathies	0.003	0.997	0.000
M34.9 Systemic sclerosis, unspecified	0.003	0.997	0.000
E10.8 With unspecified complications	0.003	0.997	0.000
H65.3 Chronic mucoid otitis media	0.000	0.997	0.003
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.003	0.997	0.000
M31.9 Necrotising vasculopathy, unspecified	0.003	0.997	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.003	0.997	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.000	0.997	0.003
E10.7 With multiple complications	0.003	0.997	0.000
E10.6 With other specified complications	0.003	0.997	0.000
Z97 Presence of other devices	0.003	0.997	0.000
H92.0 Otalgia	0.000	0.997	0.003
M34.1 CR(E)ST syndrome	0.003	0.997	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.003	0.997	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.003	0.997	0.000
M31.2 Lethal midline granuloma	0.003	0.997	0.000
M31.0 Hypersensitivity angiitis	0.003	0.997	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.003	0.997	0.000
M34.8 Other forms of systemic sclerosis	0.003	0.997	0.000
E10.2 With renal complications	0.003	0.997	0.000
K70.0 Alcoholic fatty liver	0.003	0.997	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.003	0.997	0.000
M31.1 Thrombotic microangiopathy	0.003	0.997	0.000
M34 Systemic sclerosis	0.003	0.997	0.000
M31.3 Wegener's granulomatosis	0.003	0.997	0.000
Z97.1 Presence of artificial limb (complete)(partial)	0.003	0.997	0.000
M31.7 Microscopic polyangiitis	0.002	0.997	0.000
J69 Pneumonitis due to solids and liquids	0.000	0.997	0.003
I49.5 Sick sinus syndrome	0.003	0.997	0.000
S06.3 Focal brain injury	0.002	0.997	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.002	0.997	0.000
N20.0 Calculus of kidney	0.002	0.998	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.000	0.998	0.002
H62.4 Otitis externa in other diseases classified elsewhere	0.000	0.998	0.002
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
H62.2 Otitis externa in mycoses	0.000	0.998	0.002
H62.1 Otitis externa in viral diseases classified elsewhere	0.000	0.998	0.002
H21 Other disorders of iris and ciliary body	0.002	0.998	0.000
H80-H83 Diseases of inner ear	0.000	0.998	0.002
S06 Intracranial injury	0.002	0.998	0.000
H21.0 Hyphaema	0.002	0.998	0.000
Z97.0 Presence of artificial eye	0.002	0.998	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.998	0.002
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.000	0.998	0.002
E11.2 With renal complications	0.002	0.998	0.000
S06.0 Concussion	0.002	0.998	0.000
S06.00 Concussion (without open intracranial wound)	0.002	0.998	0.000
M34.0 Progressive systemic sclerosis	0.002	0.998	0.000
S06.8 Other intracranial injuries	0.002	0.998	0.000
E10.1 With ketoacidosis	0.002	0.998	0.000
K86.2 Cyst of pancreas	0.002	0.998	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.002	0.998	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.002	0.998	0.000
Z97.2 Presence of dental prosthetic device (complete)(partial)	0.002	0.998	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.002	0.998	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.000	0.998	0.002
G31.8 Other specified degenerative diseases of nervous system	0.000	0.998	0.002
H21.2 Degeneration of iris and ciliary body	0.002	0.998	0.000
M54.3 Sciatica	0.002	0.998	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.998	0.002
S06.2 Diffuse brain injury	0.002	0.998	0.000
E87.7 Fluid overload	0.002	0.998	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.002	0.998	0.000
J69.1 Pneumonitis due to oils and essences	0.000	0.998	0.002
S06.6 Traumatic subarachnoid haemorrhage	0.002	0.998	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.002	0.998	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.002	0.998	0.000
S06.1 Traumatic cerebral oedema	0.002	0.998	0.000
N76.6 Ulceration of vulva	0.002	0.998	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.000	0.998	0.002
G63.2 Diabetic polyneuropathy	0.002	0.998	0.000
N76.4 Abscess of vulva	0.002	0.998	0.000
I46 Cardiac arrest	0.000	0.998	0.002
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.998	0.002
E11.4 With neurological complications	0.002	0.998	0.000
M41.86 Other forms of scoliosis (Lumbar region)	0.002	0.998	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.002	0.998	0.000
N20.1 Calculus of ureter	0.002	0.998	0.000
N70.9 Salpingitis and oophoritis, unspecified	0.002	0.998	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.000	0.998	0.002
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.998	0.002
M54.30 Sciatica (Multiple sites in spine)	0.002	0.998	0.000
H21.8 Other specified disorders of iris and ciliary body	0.002	0.998	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.002	0.998	0.000
S06.7 Intracranial injury with prolonged coma	0.002	0.998	0.000
Z97.3 Presence of spectacles and contact lenses	0.002	0.998	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.002	0.998	0.000
S06.4 Epidural haemorrhage	0.002	0.998	0.000
Z01.5 Diagnostic skin and sensitisation tests	0.000	0.998	0.002
R47 Speech disturbances, not elsewhere classified	0.002	0.998	0.000
H21.4 Pupillary membranes	0.002	0.998	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.002	0.998	0.000
S06.01 Concussion (with open intracranial wound)	0.002	0.998	0.000
Q05.9 Spina bifida, unspecified	0.000	0.998	0.002
S06.9 Intracranial injury, unspecified	0.002	0.998	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.002	0.998	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.002	0.998	0.000
J94.8 Other specified pleural conditions	0.000	0.998	0.002
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.002	0.998	0.000
N76.8 Other specified inflammation of vagina and vulva	0.002	0.998	0.000
M54.35 Sciatica (Thoracolumbar region)	0.002	0.998	0.000
M54.34 Sciatica-Thoracic	0.002	0.998	0.000
M54.33 Sciatica-Cervicothoracic	0.002	0.998	0.000
M54.32 Sciatica-Cervical	0.002	0.998	0.000
M54.31 Sciatica-Occipit-atl-axl	0.002	0.998	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.002	0.998	0.000
J69.8 Pneumonitis due to other solids and liquids	0.000	0.998	0.002
R47.1 Dysarthria and anarthria	0.002	0.998	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.002	0.998	0.000
S06.5 Traumatic subdural haemorrhage	0.002	0.998	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.002	0.998	0.000
S02.00 Fracture of vault of skull (closed)	0.002	0.998	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.002	0.998	0.000
J94.2 Haemothorax	0.000	0.998	0.002
K70.1 Alcoholic hepatitis	0.002	0.998	0.000
T86.1 Kidney transplant failure and rejection	0.002	0.998	0.000
N76 Other inflammation of vagina and vulva	0.002	0.998	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.002	0.998	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.002	0.998	0.000
C67.2 Lateral wall of bladder	0.002	0.998	0.000
K25.3 Acute without haemorrhage or perforation	0.002	0.998	0.000
N76.5 Ulceration of vagina	0.002	0.998	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.002	0.998	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.002	0.998	0.000
K70.4 Alcoholic hepatic failure	0.002	0.998	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.002	0.998	0.000
N76.1 Subacute and chronic vaginitis	0.002	0.998	0.000
K70 Alcoholic liver disease	0.002	0.998	0.000
N85.9 Noninflammatory disorder of uterus, unspecified	0.002	0.998	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.001	0.998	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.001	0.998	0.000
M35.7 Hypermobility syndrome	0.000	0.998	0.002
H80 Otosclerosis	0.001	0.998	0.001
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.002	0.998	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.002	0.998	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.001	0.998	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.002	0.998	0.000
N18.2 Chronic kidney disease, stage 2	0.000	0.998	0.002
Z01.4 Gynaecological examination (general)(routine)	0.000	0.998	0.002
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.001	0.998	0.000
M22.4 Chondromalacia patellae	0.000	0.998	0.002
I24 Other acute ischaemic heart diseases	0.000	0.998	0.002
I24.1 Dressler's syndrome	0.000	0.998	0.002
I46.1 Sudden cardiac death, so described	0.000	0.998	0.001
L97 Ulcer of lower limb, not elsewhere classified	0.002	0.998	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.001	0.998	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.001	0.998	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.002	0.998	0.000
I78.1 Naevus, nonneoplastic	0.000	0.998	0.002
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.001	0.998	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.002	0.998	0.000
E10.9 Without complications	0.002	0.998	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.998	0.002
O14.1 Severe preeclampsia	0.000	0.998	0.002
R40.0 Somnolence	0.000	0.998	0.002
Z97.8 Presence of other specified devices	0.002	0.998	0.000
N76.3 Subacute and chronic vulvitis	0.001	0.998	0.000
O43.1 Malformation of placenta	0.002	0.998	0.000
S79.9 Unspecified injury of hip and thigh	0.002	0.998	0.000
Y48.4 Anaesthetic, unspecified	0.000	0.998	0.002
Z34.0 Supervision of normal first pregnancy	0.002	0.998	0.000
E13 Other specified diabetes mellitus	0.001	0.998	0.000
E10-E14 Diabetes mellitus	0.002	0.998	0.000
M79.65 Pain in limb (Pelvic region and thigh)	0.002	0.998	0.000
C34.3 Lower lobe, bronchus or lung	0.002	0.998	0.000
H60 Otitis externa	0.000	0.998	0.001
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.998	0.001
H52.1 Myopia	0.002	0.998	0.000
H80.9 Otosclerosis, unspecified	0.001	0.998	0.000
J02 Acute pharyngitis	0.001	0.998	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.000	0.998	0.001
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.001	0.999	0.000
H80.2 Cochlear otosclerosis	0.001	0.999	0.001
H80.1 Otosclerosis involving oval window, obliterative	0.001	0.999	0.001
M79.60 Pain in limb (Multiple sites)	0.001	0.999	0.000
E13.3 With ophthalmic complications	0.001	0.999	0.000
G57.8 Other mononeuropathies of lower limb	0.000	0.999	0.001
H80.8 Other otosclerosis	0.001	0.999	0.001
H80.0 Otosclerosis involving oval window, nonobliterative	0.001	0.999	0.001
K86.3 Pseudocyst of pancreas	0.001	0.999	0.000
R87.6 Abnormal cytological findings	0.001	0.999	0.000
M25.46 Effusion of joint (Lower leg)	0.000	0.999	0.001
D23.4 Skin of scalp and neck	0.001	0.999	0.000
J02.8 Acute pharyngitis due to other specified organisms	0.001	0.999	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.001	0.999	0.000
I46.9 Cardiac arrest, unspecified	0.000	0.999	0.001
J94 Other pleural conditions	0.000	0.999	0.001
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.001	0.999	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.999	0.001
E13.9 Without complications	0.001	0.999	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.000	0.999	0.001
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.999	0.001
K22.7 Barrett's oesophagus	0.000	0.999	0.001
K86.0 Alcohol-induced chronic pancreatitis	0.001	0.999	0.000
M07.3 Other psoriatic arthropathies	0.000	0.999	0.001
N76.0 Acute vaginitis	0.001	0.999	0.000
K70.3 Alcoholic cirrhosis of liver	0.001	0.999	0.000
S52.50 Fracture of lower end of radius (closed)	0.000	0.999	0.001
C34.9 Bronchus or lung, unspecified	0.001	0.999	0.000
E13.8 With unspecified complications	0.001	0.999	0.000
E13.7 With multiple complications	0.001	0.999	0.000
E13.6 With other specified complications	0.001	0.999	0.000
E13.5 With peripheral circulatory complications	0.001	0.999	0.000
E13.4 With neurological complications	0.001	0.999	0.000
E13.2 With renal complications	0.001	0.999	0.000
E13.1 With ketoacidosis	0.001	0.999	0.000
E13.0 With coma	0.001	0.999	0.000
E12 Malnutrition-related diabetes mellitus	0.001	0.999	0.000
M54.12 Radiculopathy (Cervical region)	0.000	0.999	0.001
J38.7 Other diseases of larynx	0.001	0.999	0.000
O14.0 Moderate preeclampsia	0.000	0.999	0.001
K37 Unspecified appendicitis	0.001	0.999	0.000
S02.30 Fracture of orbital floor (closed)	0.001	0.999	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.999	0.001
H60.3 Other infective otitis externa	0.000	0.999	0.001
M80 Osteoporosis with pathological fracture	0.000	0.999	0.001
T15 Foreign body on external eye	0.000	0.999	0.001
M00.94 Pyogenic arthritis, unspecified (Hand)	0.000	0.999	0.001
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.999	0.001
M54.37 Sciatica (Lumbosacral region)	0.001	0.999	0.000
H53.8 Other visual disturbances	0.001	0.999	0.000
T16 Foreign body in ear	0.000	0.999	0.001
M07.38 Other psoriatic arthropathies (Other)	0.000	0.999	0.001
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.000	0.999	0.001
H60.5 Acute otitis externa, non-infective	0.000	0.999	0.001
H60.2 Malignant otitis externa	0.000	0.999	0.001
J94.1 Fibrothorax	0.000	0.999	0.001
J94.0 Chylous effusion	0.000	0.999	0.001
O81.0 Low forceps delivery	0.000	0.999	0.001
K86 Other diseases of pancreas	0.001	0.999	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.999	0.001
E11.8 With unspecified complications	0.001	0.999	0.000
G93.6 Cerebral oedema	0.000	0.999	0.001
M41.8 Other forms of scoliosis	0.001	0.999	0.000
O41.0 Oligohydramnios	0.000	0.999	0.001
T15.1 Foreign body in conjunctival sac	0.000	0.999	0.001
T19 Foreign body in genito-urinary tract	0.000	0.999	0.001
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.999	0.001
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.999	0.001
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.999	0.001
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.999	0.001
C18.9 Colon, unspecified	0.001	0.999	0.000
H60.0 Abscess of external ear	0.000	0.999	0.001
O47.0 False labour before 37 completed weeks of gestation	0.000	0.999	0.001
M25.45 Effusion of joint (Pelvic region and thigh)	0.000	0.999	0.001
E12.9 Without complications	0.001	0.999	0.000
E12.8 With unspecified complications	0.001	0.999	0.000
E12.7 With multiple complications	0.001	0.999	0.000
E12.6 With other specified complications	0.001	0.999	0.000
E12.5 With peripheral circulatory complications	0.001	0.999	0.000
E12.4 With neurological complications	0.001	0.999	0.000
E12.3 With ophthalmic complications	0.001	0.999	0.000
E12.2 With renal complications	0.001	0.999	0.000
E12.1 With ketoacidosis	0.001	0.999	0.000
E12.0 With coma	0.001	0.999	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.999	0.001
K86.9 Disease of pancreas, unspecified	0.001	0.999	0.000
M41.85 Other forms of scoliosis (Thoracolumbar region)	0.001	0.999	0.000
J94.9 Pleural condition, unspecified	0.000	0.999	0.001
C34.0 Main bronchus	0.001	0.999	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.000	0.999	0.001
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.000	0.999	0.001
M80.2 Osteoporosis of disuse with pathological fracture	0.000	0.999	0.001
S02.0 Fracture of vault of skull	0.001	0.999	0.000
T15.8 Foreign body in other and multiple parts of external eye	0.000	0.999	0.001
C73 Malignant neoplasm of thyroid gland	0.000	0.999	0.001
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.999	0.001
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.001	0.999	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.000	0.999	0.001
H60.9 Otitis externa, unspecified	0.000	0.999	0.001
H60.4 Cholesteatoma of external ear	0.000	0.999	0.001
J02.0 Streptococcal pharyngitis	0.001	0.999	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.999	0.001
T86.8 Failure and rejection of other transplanted organs and tissues	0.001	0.999	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M41.89 Other forms of scoliosis (Site unspecified)	0.001	0.999	0.000
M41.88 Other forms of scoliosis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M41.87 Other forms of scoliosis (Lumbosacral region)	0.001	0.999	0.000
M41.84 Other forms of scoliosis (Thoracic region)	0.001	0.999	0.000
M41.83 Other forms of scoliosis (Cervicothoracic region)	0.001	0.999	0.000
M41.82 Other forms of scoliosis (Cervical region)	0.001	0.999	0.000
M41.81 Other forms of scoliosis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M41.80 Other forms of scoliosis (Multiple sites in spine)	0.001	0.999	0.000
T15.0 Foreign body in cornea	0.000	0.999	0.001
T19.9 Foreign body in genito-urinary tract, part unspecified	0.000	0.999	0.001
T19.8 Foreign body in other and multiple parts of genito-urinary tract	0.000	0.999	0.001
T19.3 Foreign body in uterus [any part]	0.000	0.999	0.001
T19.1 Foreign body in bladder	0.000	0.999	0.001
E11 Non-insulin-dependent diabetes mellitus	0.001	0.999	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.999	0.001
M66.46 Spontaneous rupture of other tendons (Lower leg)	0.000	0.999	0.001
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.000	0.999	0.001
D37.0 Lip, oral cavity and pharynx	0.000	0.999	0.001
J18.0 Bronchopneumonia, unspecified	0.001	0.999	0.000
J92.0 Pleural plaque with presence of asbestos	0.001	0.999	0.000
T15.9 Foreign body on external eye, unspecified	0.000	0.999	0.001
T19.2 Foreign body in vulva and vagina	0.000	0.999	0.001
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.000	0.999	0.001
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.000	0.999	0.001
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.000	0.999	0.001
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.000	0.999	0.001
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.000	0.999	0.001
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.000	0.999	0.001
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.000	0.999	0.001
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.000	0.999	0.001
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.000	0.999	0.001
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.000	0.999	0.001
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.000	0.999	0.001
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.000	0.999	0.001
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.000	0.999	0.001
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.000	0.999	0.001
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.999	0.001
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.000	0.999	0.001
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.000	0.999	0.001
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.000	0.999	0.001
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.000	0.999	0.001
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.000	0.999	0.001
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.000	0.999	0.001
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.000	0.999	0.001
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.000	0.999	0.001
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.000	0.999	0.001
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.999	0.001
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.000	0.999	0.001
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.000	0.999	0.001
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.000	0.999	0.001
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.000	0.999	0.001
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.000	0.999	0.001
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.001	0.999	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.001	0.999	0.000
H60.8 Other otitis externa	0.000	0.999	0.001
O14.2 HELLP syndrome	0.000	0.999	0.001
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.000	0.999	0.001
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.000	0.999	0.001
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.000	0.999	0.001
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.000	0.999	0.001
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.999	0.001
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.000	0.999	0.001
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.000	0.999	0.001
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.000	0.999	0.001
E14.8 With unspecified complications	0.001	0.999	0.000
K38.9 Disease of appendix, unspecified	0.001	0.999	0.000
M35.8 Other specified systemic involvement of connective tissue	0.000	0.999	0.001
M35.3 Polymyalgia rheumatica	0.000	0.999	0.001
T19.0 Foreign body in urethra	0.000	0.999	0.001
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.001	0.999	0.000
M43.10 Spondylolisthesis (Multiple sites in spine)	0.001	0.999	0.000
I82.8 Embolism and thrombosis of other specified veins	0.001	0.999	0.000
S02.01 Fracture of vault of skull (open)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations