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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1015868
log Bayes Factor = 56.7068
Chromosome 6   position 29,485,373  (GRCh37) Explore rs1015868 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
1.000 0.000 0.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.999 0.001 0.000
E20-E35 Disorders of other endocrine glands
0.998 0.002 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.996 0.004 0.000
E10.2 With renal complications
0.994 0.006 0.000
E10.1 With ketoacidosis
0.993 0.007 0.000
E14 Unspecified diabetes mellitus
0.993 0.007 0.000
E27 Other disorders of adrenal gland
0.992 0.008 0.000
E27.1 Primary adrenocortical insufficiency
0.989 0.011 0.000
E05.9 Thyrotoxicosis, unspecified
0.984 0.016 0.000
E14.3 With ophthalmic complications
0.977 0.023 0.000
E24 Cushing's syndrome
0.969 0.031 0.000
E10.4 With neurological complications
0.968 0.032 0.000
E50-E64 Other nutritional deficiencies
0.953 0.047 0.000
E13 Other specified diabetes mellitus
0.917 0.083 0.000
E24.9 Cushing's syndrome, unspecified
0.882 0.118 0.000
E07 Other disorders of thyroid
0.875 0.125 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.868 0.132 0.000
E03 Other hypothyroidism
0.858 0.142 0.000
E24.0 Pituitary-dependent Cushing's disease
0.856 0.144 0.000
E13.9 Without complications
0.853 0.147 0.000
E06 Thyroiditis
0.849 0.151 0.000
E55 Vitamin D deficiency
0.840 0.160 0.000
E61 Deficiency of other nutrient elements
0.839 0.161 0.000
E20 Hypoparathyroidism
0.838 0.162 0.000
E11 Non-insulin-dependent diabetes mellitus
0.838 0.162 0.000
E11.9 Without complications
0.819 0.181 0.000
E22 Hyperfunction of pituitary gland
0.815 0.185 0.000
E10.7 With multiple complications
0.813 0.187 0.000
E10.5 With peripheral circulatory complications
0.813 0.187 0.000
E11.2 With renal complications
0.808 0.192 0.000
E24.8 Other Cushing's syndrome
0.807 0.193 0.000
E10.0 With coma
0.802 0.198 0.000
E14.6 With other specified complications
0.795 0.205 0.000
E03.9 Hypothyroidism, unspecified
0.794 0.206 0.000
E14.5 With peripheral circulatory complications
0.790 0.209 0.000
K90 Intestinal malabsorption
0.790 0.210 0.000
E51 Thiamine deficiency
0.783 0.217 0.000
E14.0 With coma
0.779 0.221 0.000
E07.9 Disorder of thyroid, unspecified
0.777 0.223 0.000
E16 Other disorders of pancreatic internal secretion
0.774 0.226 0.000
E55.9 Vitamin D deficiency, unspecified
0.759 0.241 0.000
E23 Hypofunction and other disorders of pituitary gland
0.756 0.244 0.000
E25 Adrenogenital disorders
0.752 0.248 0.000
K90.9 Intestinal malabsorption, unspecified
0.751 0.249 0.000
E14.8 With unspecified complications
0.747 0.253 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.742 0.258 0.000
E10.6 With other specified complications
0.741 0.259 0.000
E14.2 Withrenal complications
0.741 0.259 0.000
E22.0 Acromegaly and pituitary gigantism
0.738 0.262 0.000
E61.1 Iron deficiency
0.734 0.266 0.000
E10.8 With unspecified complications
0.728 0.272 0.000
E29 Testicular dysfunction
0.727 0.273 0.000
E20.9 Hypoparathyroidism, unspecified
0.724 0.276 0.000
E27.8 Other specified disorders of adrenal gland
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.716 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.716 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.716 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.716 0.283 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.716 0.284 0.000
E32 Diseases of thymus
0.716 0.284 0.000
E30 Disorders of puberty, not elsewhere classified
0.716 0.284 0.000
E14.9 Without complications
0.713 0.287 0.000
E14.7 With multiple complications
0.712 0.288 0.000
E27.5 Adrenomedullary hyperfunction
0.711 0.289 0.000
E27.0 Other adrenocortical overactivity
0.711 0.289 0.000
E53 Deficiency of other B group vitamins
0.710 0.290 0.000
E31 Polyglandular dysfunction
0.709 0.291 0.000
E06.3 Autoimmune thyroiditis
0.709 0.291 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.704 0.296 0.000
E24.2 Drug-induced Cushing's syndrome
0.701 0.299 0.000
E06.9 Thyroiditis, unspecified
0.700 0.300 0.000
E14.4 With neurological complications
0.698 0.302 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.695 0.305 0.000
E24.3 Ectopic ACTH syndrome
0.695 0.305 0.000
E24.1 Nelson's syndrome
0.695 0.305 0.000
E14.1 With ketoacidosis
0.691 0.309 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.691 0.309 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.683 0.316 0.000
E63 Other nutritional deficiencies
0.683 0.316 0.000
E50 Vitamin A deficiency
0.683 0.316 0.000
E60 Dietary zinc deficiency
0.683 0.316 0.000
E59 Dietary selenium deficiency
0.683 0.316 0.000
E54 Ascorbic acid deficiency
0.683 0.316 0.000
E52 Niacin deficiency [pellagra]
0.683 0.316 0.000
E28 Ovarian dysfunction
0.682 0.318 0.000
E13.3 With ophthalmic complications
0.676 0.324 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.675 0.325 0.000
E16.1 Other hypoglycaemia
0.665 0.335 0.000
E51.2 Wernicke's encephalopathy
0.660 0.340 0.000
E56 Other vitamin deficiencies
0.659 0.341 0.000
E13.8 With unspecified complications
0.657 0.342 0.000
E13.7 With multiple complications
0.657 0.342 0.000
E13.6 With other specified complications
0.657 0.342 0.000
E13.5 With peripheral circulatory complications
0.657 0.342 0.000
E13.4 With neurological complications
0.657 0.342 0.000
E13.2 With renal complications
0.657 0.342 0.000
E13.1 With ketoacidosis
0.657 0.342 0.000
E13.0 With coma
0.657 0.342 0.000
E23.0 Hypopituitarism
0.657 0.343 0.000
E11.7 With multiple complications
0.656 0.344 0.000
E61.2 Magnesium deficiency
0.654 0.346 0.000
E07.8 Other specified disorders of thyroid
0.651 0.349 0.000
E58 Dietary calcium deficiency
0.650 0.350 0.000
E05.8 Other thyrotoxicosis
0.647 0.352 0.000
E06.1 Subacute thyroiditis
0.646 0.353 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.638 0.362 0.000
E03.1 Congenital hypothyroidism without goitre
0.633 0.367 0.000
E07.1 Dyshormogenetic goitre
0.628 0.372 0.000
E07.0 Hypersecretion of calcitonin
0.628 0.372 0.000
E15 Nondiabetic hypoglycaemic coma
0.622 0.377 0.000
E53.9 Vitamin B deficiency, unspecified
0.621 0.379 0.000
E16.2 Hypoglycaemia, unspecified
0.619 0.381 0.000
E03.5 Myxoedema coma
0.615 0.385 0.000
E03.4 Atrophy of thyroid (acquired)
0.615 0.385 0.000
E03.3 Postinfectious hypothyroidism
0.615 0.385 0.000
E06.4 Drug-induced thyroiditis
0.609 0.391 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.609 0.391 0.000
E06.0 Acute thyroiditis
0.609 0.391 0.000
E55.0 Rickets, active
0.602 0.398 0.000
E61.9 Deficiency of nutrient element, unspecified
0.602 0.398 0.000
E61.8 Deficiency of other specified nutrient elements
0.602 0.398 0.000
E61.7 Deficiency of multiple nutrient elements
0.602 0.398 0.000
E61.6 Vanadium deficiency
0.602 0.398 0.000
E61.5 Molybdenum deficiency
0.602 0.398 0.000
E61.4 Chromium deficiency
0.602 0.398 0.000
E61.3 Manganese deficiency
0.602 0.398 0.000
E61.0 Copper deficiency
0.602 0.398 0.000
E20.8 Other hypoparathyroidism
0.601 0.399 0.000
E20.1 Pseudohypoparathyroidism
0.601 0.399 0.000
E20.0 Idiopathic hypoparathyroidism
0.601 0.399 0.000
K90.8 Other intestinal malabsorption
0.597 0.402 0.000
E40-E46 Malnutrition
0.586 0.413 0.000
E22.8 Other hyperfunction of pituitary gland
0.584 0.415 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.581 0.419 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.575 0.424 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.572 0.428 0.000
E26 Hyperaldosteronism
0.571 0.429 0.000
E29.9 Testicular dysfunction, unspecified
0.570 0.430 0.000
K90.3 Pancreatic steatorrhoea
0.566 0.434 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.566 0.434 0.000
K90.1 Tropical sprue
0.566 0.434 0.000
E27.9 Disorder of adrenal gland, unspecified
0.562 0.437 0.000
E23.2 Diabetes insipidus
0.562 0.438 0.000
E22.1 Hyperprolactinaemia
0.562 0.438 0.000
E51.9 Thiamine deficiency, unspecified
0.561 0.439 0.000
E51.8 Other manifestations of thiamine deficiency
0.561 0.439 0.000
E51.1 Beriberi
0.561 0.439 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.555 0.445 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.555 0.445 0.000
E16.4 Abnormal secretion of gastrin
0.555 0.445 0.000
E16.3 Increased secretion of glucagon
0.555 0.445 0.000
E27.2 Addisonian crisis
0.553 0.447 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.542 0.458 0.000
E23.1 Drug-induced hypopituitarism
0.542 0.458 0.000
E25.9 Adrenogenital disorder, unspecified
0.539 0.461 0.000
E25.8 Other adrenogenital disorders
0.539 0.461 0.000
E03.8 Other specified hypothyroidism
0.537 0.463 0.000
E11.8 With unspecified complications
0.533 0.467 0.000
E29.8 Other testicular dysfunction
0.521 0.479 0.000
E29.0 Testicular hyperfunction
0.521 0.479 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
E30.9 Disorder of puberty, unspecified
0.513 0.487 0.000
E30.8 Other disorders of puberty
0.513 0.487 0.000
E30.1 Precocious puberty
0.513 0.487 0.000
E30.0 Delayed puberty
0.513 0.487 0.000
E32.9 Disease of thymus, unspecified
0.513 0.487 0.000
E32.8 Other diseases of thymus
0.513 0.487 0.000
E32.1 Abscess of thymus
0.513 0.487 0.000
E32.0 Persistent hyperplasia of thymus
0.513 0.487 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.513 0.487 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.513 0.487 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.513 0.487 0.000
E53.1 Pyridoxine deficiency
0.509 0.490 0.000
E53.0 Riboflavin deficiency
0.509 0.490 0.000
E31.9 Polyglandular dysfunction, unspecified
0.508 0.492 0.000
E31.8 Other polyglandular dysfunction
0.508 0.492 0.000
E31.1 Polyglandular hyperfunction
0.508 0.492 0.000
E34 Other endocrine disorders
0.501 0.499 0.000
E31.0 Autoimmune polyglandular failure
0.501 0.499 0.000
E06.5 Other chronic thyroiditis
0.497 0.503 0.000
E50.9 Vitamin A deficiency, unspecified
0.490 0.510 0.000
E50.8 Other manifestations of vitamin A deficiency
0.490 0.510 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.490 0.510 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.490 0.510 0.000
E50.5 Vitamin A deficiency with night blindness
0.490 0.510 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.490 0.510 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.490 0.510 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.490 0.510 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.490 0.510 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.490 0.510 0.000
E63.9 Nutritional deficiency, unspecified
0.490 0.510 0.000
E63.8 Other specified nutritional deficiencies
0.490 0.510 0.000
E63.1 Imbalance of constituents of food intake
0.490 0.510 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.490 0.510 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.490 0.510 0.000
E64.8 Sequelae of other nutritional deficiencies
0.490 0.510 0.000
E64.3 Sequelae of rickets
0.490 0.510 0.000
E64.2 Sequelae of vitamin C deficiency
0.490 0.510 0.000
E64.1 Sequelae of vitamin A deficiency
0.490 0.510 0.000
E64.0 Sequelae of protein-energy malnutrition
0.490 0.510 0.000
E28.9 Ovarian dysfunction, unspecified
0.489 0.511 0.000
E28.8 Other ovarian dysfunction
0.489 0.511 0.000
E28.1 Androgen excess
0.489 0.511 0.000
E28.0 Oestrogen excess
0.489 0.511 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.485 0.515 0.000
E23.7 Disorder of pituitary gland, unspecified
0.481 0.519 0.000
E28.3 Primary ovarian failure
0.479 0.520 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.475 0.525 0.000
E56.9 Vitamin deficiency, unspecified
0.472 0.527 0.000
E56.8 Deficiency of other vitamins
0.472 0.527 0.000
E56.0 Deficiency of vitamin E
0.472 0.527 0.000
E29.1 Testicular hypofunction
0.472 0.528 0.000
E28.2 Polycystic ovarian syndrome
0.466 0.534 0.000
E56.1 Deficiency of vitamin K
0.448 0.552 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.440 0.559 0.000
E11.5 With peripheral circulatory complications
0.436 0.564 0.000
E23.6 Other disorders of pituitary gland
0.434 0.566 0.000
E11.0 With coma
0.431 0.568 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.421 0.579 0.000
E45 Retarded development following protein-energy malnutrition
0.421 0.579 0.000
E43 Unspecified severe protein-energy malnutrition
0.421 0.579 0.000
E42 Marasmic kwashiorkor
0.421 0.579 0.000
E41 Nutritional marasmus
0.421 0.579 0.000
E40 Kwashiorkor
0.421 0.579 0.000
E26.9 Hyperaldosteronism, unspecified
0.420 0.579 0.000
E11.6 With other specified complications
0.411 0.588 0.000
E26.8 Other hyperaldosteronism
0.409 0.591 0.000
E26.1 Secondary hyperaldosteronism
0.409 0.591 0.000
E11.1 With ketoacidosis
0.392 0.608 0.000
E11.3 With ophthalmic complications
0.379 0.621 0.000
E34.8 Other specified endocrine disorders
0.372 0.628 0.000
E34.5 Androgen resistance syndrome
0.359 0.640 0.000
E34.4 Constitutional tall stature
0.359 0.640 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.359 0.640 0.000
E34.1 Other hypersecretion of intestinal hormones
0.359 0.640 0.000
E34.3 Short stature, not elsewhere classified
0.352 0.648 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.348 0.652 0.000
E21.4 Other specified disorders of parathyroid gland
0.347 0.653 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.326 0.674 0.000
M35.0 Sicca syndrome [Sjogren]
0.323 0.677 0.000
E21.0 Primary hyperparathyroidism
0.323 0.677 0.000
E53.8 Deficiency of other specified B group vitamins
0.318 0.682 0.000
E21.2 Other hyperparathyroidism
0.307 0.692 0.000
E44.1 Mild protein-energy malnutrition
0.302 0.698 0.000
E44.0 Moderate protein-energy malnutrition
0.302 0.698 0.000
M35 Other systemic involvement of connective tissue
0.300 0.700 0.000
E21.3 Hyperparathyroidism, unspecified
0.299 0.701 0.000
E65-E68 Obesity and other hyperalimentation
0.292 0.708 0.000
E46 Unspecified protein-energy malnutrition
0.290 0.710 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.280 0.720 0.000
E34.0 Carcinoid syndrome
0.276 0.724 0.000
M35.3 Polymyalgia rheumatica
0.274 0.726 0.000
E34.9 Endocrine disorder, unspecified
0.268 0.731 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.249 0.751 0.000
M31.6 Other giant cell arteritis
0.244 0.756 0.000
E26.0 Primary hyperaldosteronism
0.241 0.759 0.001
M31 Other necrotising vasculopathies
0.237 0.763 0.000
M20-M25 Other joint disorders
0.231 0.769 0.000
E11.4 With neurological complications
0.228 0.772 0.000
K50 Crohn's disease [regional enteritis]
0.000 0.772 0.228
K50.0 Crohn's disease of small intestine
0.000 0.774 0.226
M22.2 Patellofemoral disorders
0.225 0.775 0.000
M22 Disorders of patella
0.225 0.775 0.000
K50.9 Crohn's disease, unspecified
0.000 0.778 0.222
M35.1 Other overlap syndromes
0.220 0.780 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.215 0.785 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.215 0.785 0.000
M35.5 Multifocal fibrosclerosis
0.215 0.785 0.000
K51 Ulcerative colitis
0.000 0.785 0.215
M35.8 Other specified systemic involvement of connective tissue
0.215 0.785 0.000
K50-K52 Noninfective enteritis and colitis
0.000 0.790 0.210
K51.2 Ulcerative (chronic) proctitis
0.000 0.790 0.210
E67 Other hyperalimentation
0.209 0.791 0.000
E68 Sequelae of hyperalimentation
0.209 0.791 0.000
M32 Systemic lupus erythematosus
0.208 0.792 0.000
K51.4 Pseudopolyposis of colon
0.000 0.798 0.202
M35.7 Hypermobility syndrome
0.202 0.798 0.000
M35.2 Behcet's disease
0.201 0.799 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.197 0.803 0.000
M34 Systemic sclerosis
0.196 0.804 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.185 0.814 0.000
E04 Other non-toxic goitre
0.185 0.814 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.184 0.816 0.000
K50.1 Crohn's disease of large intestine
0.000 0.821 0.179
M31.8 Other specified necrotising vasculopathies
0.174 0.825 0.000
M22.8 Other disorders of patella
0.173 0.827 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.829 0.171
M31.9 Necrotising vasculopathy, unspecified
0.170 0.830 0.000
M31.2 Lethal midline granuloma
0.170 0.830 0.000
M32.8 Other forms of systemic lupus erythematosus
0.170 0.830 0.000
M31.0 Hypersensitivity angiitis
0.170 0.830 0.000
M30 Polyarteritis nodosa and related conditions
0.169 0.831 0.000
M31.1 Thrombotic microangiopathy
0.168 0.831 0.000
K51.5 Mucosal proctocolitis
0.000 0.833 0.167
M31.7 Microscopic polyangiitis
0.167 0.833 0.000
M34.8 Other forms of systemic sclerosis
0.165 0.834 0.000
K51.9 Ulcerative colitis, unspecified
0.000 0.838 0.162
M22.1 Recurrent subluxation of patella
0.161 0.838 0.000
K50.8 Other Crohn's disease
0.000 0.839 0.161
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.160 0.840 0.000
M22.0 Recurrent dislocation of patella
0.157 0.842 0.000
M22.9 Disorder of patella, unspecified
0.155 0.845 0.000
M22.3 Other derangements of patella
0.155 0.845 0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.154 0.845 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.845 0.155
M34.1 CR(E)ST syndrome
0.153 0.847 0.000
E67.8 Other specified hyperalimentation
0.150 0.850 0.000
E67.3 Hypervitaminosis D
0.150 0.850 0.000
E67.2 Megavitamin-B6 syndrome
0.150 0.850 0.000
E67.1 Hypercarotenaemia
0.150 0.850 0.000
E67.0 Hypervitaminosis A
0.150 0.850 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.149 0.850 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.149 0.850 0.000
K51.8 Other ulcerative colitis
0.000 0.853 0.147
E04.9 Non-toxic goitre, unspecified
0.146 0.854 0.000
M34.9 Systemic sclerosis, unspecified
0.146 0.854 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.856 0.144
M34.2 Systemic sclerosis induced by drugs and chemicals
0.141 0.859 0.000
E04.8 Other specified non-toxic goitre
0.133 0.867 0.000
M34.0 Progressive systemic sclerosis
0.132 0.868 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.130 0.870 0.000
E65 Localised adiposity
0.129 0.870 0.000
M33 Dermatopolymyositis
0.128 0.872 0.000
M22.4 Chondromalacia patellae
0.124 0.876 0.000
M30.8 Other conditions related to polyarteritis nodosa
0.121 0.879 0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.121 0.879 0.000
M30.2 Juvenile polyarteritis
0.121 0.879 0.000
M22.10 Recurrent subluxation of patella, unspecified knee
0.116 0.884 0.000
M30.0 Polyarteritis nodosa
0.115 0.885 0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.115 0.885 0.000
M36.3 Arthropathy in other blood disorders
0.115 0.885 0.000
M36.2 Haemophilic arthropathy
0.115 0.885 0.000
M36.1 Arthropathy in neoplastic disease
0.115 0.885 0.000
M36.0 Dermato(poly)myositis in neoplastic disease
0.115 0.885 0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.109 0.891 0.000
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites
0.107 0.892 0.000
M31.3 Wegener's granulomatosis
0.104 0.896 0.000
M33.9 Dermatopolymyositis, unspecified
0.092 0.908 0.000
M33.0 Juvenile dermatomyositis
0.092 0.908 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.085 0.915 0.000
E04.0 Non-toxic diffuse goitre
0.079 0.920 0.000
M33.2 Polymyositis
0.077 0.922 0.000
M33.1 Other dermatomyositis
0.075 0.925 0.000
E83 Disorders of mineral metabolism
0.018 0.936 0.046
N08 Glomerular disorders in diseases classified elsewhere
0.063 0.937 0.000
E04.2 Non-toxic multinodular goitre
0.062 0.938 0.000
E70-E90 Metabolic disorders
0.056 0.944 0.000
K52 Other non-infective gastro-enteritis and colitis
0.000 0.945 0.055
E73 Lactose intolerance
0.055 0.945 0.000
E73.9 Lactose intolerance, unspecified
0.054 0.946 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.052 0.948 0.000
K90-K93 Other diseases of the digestive system
0.050 0.950 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.049 0.951 0.000
M21 Other acquired deformities of limbs
0.049 0.951 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.000 0.952 0.048
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.048 0.952 0.000
E83.8 Other disorders of mineral metabolism
0.013 0.954 0.033
E83.2 Disorders of zinc metabolism
0.013 0.954 0.033
E83.0 Disorders of copper metabolism
0.013 0.954 0.033
E83.9 Disorder of mineral metabolism, unspecified
0.013 0.955 0.032
N08.8 Glomerular disorders in other diseases classified elsewhere
0.045 0.955 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.045 0.955 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.045 0.955 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.044 0.956 0.000
E84 Cystic fibrosis
0.044 0.956 0.000
H36.0 Diabetic retinopathy
0.043 0.957 0.000
E79 Disorders of purine and pyrimidine metabolism
0.043 0.957 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.000 0.958 0.041
Z99.1 Dependence on respirator
0.041 0.959 0.000
E70 Disorders of aromatic amino-acid metabolism
0.041 0.959 0.000
E74 Other disorders of carbohydrate metabolism
0.041 0.959 0.000
E77 Disorders of glycoprotein metabolism
0.040 0.960 0.000
E76 Disorders of glycosaminoglycan metabolism
0.040 0.960 0.000
E72 Other disorders of amino-acid metabolism
0.040 0.960 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.040 0.960 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.040 0.960 0.000
M21.8 Other specified acquired deformities of limbs
0.040 0.960 0.000
E80.4 Gilbert's syndrome
0.039 0.961 0.000
E73.8 Other lactose intolerance
0.039 0.961 0.000
E73.1 Secondary lactase deficiency
0.039 0.961 0.000
E73.0 Congenital lactase deficiency
0.039 0.961 0.000
K52.3 Indeterminate colitis
0.000 0.961 0.039
M25 Other joint disorders, not elsewhere classified
0.038 0.962 0.000
E85 Amyloidosis
0.037 0.963 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.036 0.964 0.000
N20.0 Calculus of kidney
0.000 0.964 0.036
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.036 0.964 0.000
M21.4 Flat foot [pes planus] (acquired)
0.036 0.964 0.000
M21.6 Other acquired deformities of ankle and foot
0.035 0.965 0.000
E84.9 Cystic fibrosis, unspecified
0.034 0.966 0.000
E84.0 Cystic fibrosis with pulmonary manifestations
0.034 0.966 0.000
K52.1 Toxic gastro-enteritis and colitis
0.000 0.966 0.034
E66 Obesity
0.034 0.966 0.000
E83.3 Disorders of phosphorus metabolism
0.010 0.966 0.023
M25.9 Joint disorder, unspecified
0.033 0.967 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.033 0.967 0.000
M21.7 Unequal limb length (acquired)
0.033 0.967 0.000
E80.6 Other disorders of bilirubin metabolism
0.032 0.968 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.032 0.968 0.000
E80.5 Crigler-Najjar syndrome
0.032 0.968 0.000
E80.3 Defects of catalase and peroxydase
0.032 0.968 0.000
E80.0 Hereditary erythropoietic porphyria
0.032 0.968 0.000
E84.8 Cystic fibrosis with other manifestations
0.032 0.968 0.000
E84.1 Cystic fibrosis with intestinal manifestations
0.032 0.968 0.000
M21.9 Acquired deformity of limb, unspecified
0.032 0.968 0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)
0.031 0.969 0.000
L40.9 Psoriasis, unspecified
0.000 0.969 0.031
M21.87 Other specified acquired deformities of limbs (Ankle and foot)
0.031 0.969 0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)
0.031 0.969 0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.031 0.969 0.000
E79.8 Other disorders of purine and pyrimidine metabolism
0.031 0.969 0.000
E79.1 Lesch-Nyhan syndrome
0.031 0.969 0.000
E70.3 Albinism
0.030 0.969 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.030 0.970 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.030 0.970 0.000
E70.8 Other disorders of aromatic amino-acid metabolism
0.030 0.970 0.000
E70.2 Disorders of tyrosine metabolism
0.030 0.970 0.000
E70.1 Other hyperphenylalaninaemias
0.030 0.970 0.000
E70.0 Classical phenylketonuria
0.030 0.970 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.029 0.970 0.000
E74.8 Other specified disorders of carbohydrate metabolism
0.029 0.970 0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.029 0.970 0.000
E74.2 Disorders of galactose metabolism
0.029 0.970 0.000
E74.1 Disorders of fructose metabolism
0.029 0.970 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.029 0.971 0.000
M21.1 Varus deformity, not elsewhere classified
0.029 0.971 0.000
E71.3 Disorders of fatty-acid metabolism
0.029 0.971 0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.029 0.971 0.000
E71.1 Other disorders of branched-chain amino-acid metabolism
0.029 0.971 0.000
E71.0 Maple-syrup-urine disease
0.029 0.971 0.000
E72.9 Disorder of amino-acid metabolism, unspecified
0.029 0.971 0.000
E72.8 Other specified disorders of amino-acid metabolism
0.029 0.971 0.000
E72.5 Disorders of glycine metabolism
0.029 0.971 0.000
E72.4 Disorders of ornithine metabolism
0.029 0.971 0.000
E72.3 Disorders of lysine and hydroxylysine metabolism
0.029 0.971 0.000
E72.2 Disorders of urea cycle metabolism
0.029 0.971 0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.029 0.971 0.000
E72.0 Disorders of amino-acid transport
0.029 0.971 0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.029 0.971 0.000
E76.8 Other disorders of glucosaminoglycan metabolism
0.029 0.971 0.000
E76.3 Mucopolysaccharidosis, unspecified
0.029 0.971 0.000
E76.2 Other mucopolysaccharidoses
0.029 0.971 0.000
E76.1 Mucopolysaccharidosis, type II
0.029 0.971 0.000
E76.0 Mucopolysaccharidosis, type I
0.029 0.971 0.000
E77.9 Disorder of glycoprotein metabolism, unspecified
0.029 0.971 0.000
E77.8 Other disorders of glycoprotein metabolism
0.029 0.971 0.000
E77.1 Defects in glycoprotein degradation
0.029 0.971 0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.029 0.971 0.000
E80.1 Porphyria cutanea tarda
0.029 0.971 0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)
0.029 0.971 0.000
M21.88 Other specified acquired deformities of limbs-Other
0.029 0.971 0.000
M21.84 Other specified acquired deformities of limbs (Hand)
0.029 0.971 0.000
M21.83 Other specified acquired deformities of limbs (Forearm)
0.029 0.971 0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)
0.029 0.971 0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)
0.029 0.971 0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)
0.029 0.971 0.000
E74.0 Glycogen storage disease
0.029 0.971 0.000
E85.4 Organ-limited amyloidosis
0.028 0.971 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.028 0.972 0.000
M24 Other specific joint derangements
0.028 0.972 0.000
M25.92 Joint disorder, unspecified (Upper arm)
0.028 0.972 0.000
E80.2 Other porphyria
0.028 0.972 0.000
M25.97 Joint disorder, unspecified (Ankle and foot)
0.028 0.972 0.000
M21.0 Valgus deformity, not elsewhere classified
0.028 0.972 0.000
M25.2 Flail joint
0.027 0.972 0.000
M25.1 Fistula of joint
0.027 0.972 0.000
M21.2 Flexion deformity
0.027 0.973 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.027 0.973 0.000
E85.1 Neuropathic heredofamilial amyloidosis
0.027 0.973 0.000
E85.0 Nonneuropathic heredofamilial amyloidosis
0.027 0.973 0.000
M25.94 Joint disorder, unspecified (Hand)
0.026 0.973 0.000
E85.3 Secondary systemic amyloidosis
0.026 0.974 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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