TreeWAS – Variant ID: rs10158897

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	0.000	0.000	1.000
E78.5 Hyperlipidaemia, unspecified	0.000	0.000	1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.001	0.999
E78.1 Pure hyperglyceridaemia	0.000	0.157	0.843
E78.6 Lipoprotein deficiency	0.000	0.272	0.728
E78.3 Hyperchylomicronaemia	0.000	0.283	0.717
E78.8 Other disorders of lipoprotein metabolism	0.000	0.306	0.694
E78.4 Other hyperlipidaemia	0.000	0.330	0.669
E78.2 Mixed hyperlipidaemia	0.000	0.496	0.504
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.553	0.447
E89.0 Postprocedural hypothyroidism	0.000	0.575	0.425
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.592	0.408
E70-E90 Metabolic disorders	0.000	0.594	0.406
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.677	0.323
E79 Disorders of purine and pyrimidine metabolism	0.000	0.686	0.314
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.691	0.309
E89.3 Postprocedural hypopituitarism	0.000	0.698	0.302
E84 Cystic fibrosis	0.000	0.702	0.298
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.707	0.292
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.707	0.292
E89.5 Postprocedural testicular hypofunction	0.000	0.707	0.292
E77 Disorders of glycoprotein metabolism	0.000	0.709	0.291
E76 Disorders of glycosaminoglycan metabolism	0.000	0.709	0.291
E72 Other disorders of amino-acid metabolism	0.000	0.709	0.291
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.709	0.291
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.709	0.291
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.718	0.281
E85 Amyloidosis	0.000	0.732	0.268
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.735	0.265
E89.1 Postprocedural hypoinsulinaemia	0.000	0.735	0.265
E87.6 Hypokalaemia	0.000	0.736	0.264
E80.4 Gilbert's syndrome	0.000	0.745	0.255
E80.1 Porphyria cutanea tarda	0.000	0.747	0.253
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.751	0.248
E89.2 Postprocedural hypoparathyroidism	0.000	0.752	0.248
E73 Lactose intolerance	0.000	0.754	0.246
E75.5 Other lipid storage disorders	0.000	0.761	0.239
E70 Disorders of aromatic amino-acid metabolism	0.000	0.763	0.236
E80.2 Other porphyria	0.000	0.767	0.233
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.768	0.232
E80.5 Crigler-Najjar syndrome	0.000	0.768	0.232
E80.3 Defects of catalase and peroxydase	0.000	0.768	0.232
E80.0 Hereditary erythropoietic porphyria	0.000	0.768	0.232
E89.4 Postprocedural ovarian failure	0.000	0.768	0.231
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.769	0.231
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.774	0.225
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.774	0.225
E79.1 Lesch-Nyhan syndrome	0.000	0.774	0.225
E75.6 Lipid storage disorder, unspecified	0.000	0.778	0.221
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.778	0.221
E75.3 Sphingolipidosis, unspecified	0.000	0.778	0.221
E75.2 Other sphingolipidosis	0.000	0.778	0.221
E75.1 Other gangliosidosis	0.000	0.778	0.221
E75.0 GM2 gangliosidosis	0.000	0.778	0.221
E80.6 Other disorders of bilirubin metabolism	0.000	0.780	0.220
E84.9 Cystic fibrosis, unspecified	0.000	0.780	0.220
E87.5 Hyperkalaemia	0.000	0.785	0.215
E84.8 Cystic fibrosis with other manifestations	0.000	0.786	0.213
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.786	0.213
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.786	0.213
E74 Other disorders of carbohydrate metabolism	0.000	0.790	0.210
E71.3 Disorders of fatty-acid metabolism	0.000	0.791	0.209
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.791	0.209
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.791	0.209
E71.0 Maple-syrup-urine disease	0.000	0.791	0.209
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.791	0.209
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.791	0.209
E72.5 Disorders of glycine metabolism	0.000	0.791	0.209
E72.4 Disorders of ornithine metabolism	0.000	0.791	0.209
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.791	0.209
E72.2 Disorders of urea cycle metabolism	0.000	0.791	0.209
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.791	0.209
E72.0 Disorders of amino-acid transport	0.000	0.791	0.209
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.791	0.209
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.791	0.209
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.791	0.209
E76.2 Other mucopolysaccharidoses	0.000	0.791	0.209
E76.1 Mucopolysaccharidosis, type II	0.000	0.791	0.209
E76.0 Mucopolysaccharidosis, type I	0.000	0.791	0.209
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.791	0.209
E77.8 Other disorders of glycoprotein metabolism	0.000	0.791	0.209
E77.1 Defects in glycoprotein degradation	0.000	0.791	0.209
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.791	0.209
E85.3 Secondary systemic amyloidosis	0.000	0.797	0.203
E85.8 Other amyloidosis	0.000	0.807	0.192
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.807	0.192
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.807	0.192
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.807	0.192
E87.4 Mixed disorder of acid-base balance	0.000	0.809	0.190
E85.9 Amyloidosis, unspecified	0.000	0.818	0.182
E73.8 Other lactose intolerance	0.000	0.823	0.177
E73.1 Secondary lactase deficiency	0.000	0.823	0.177
E73.0 Congenital lactase deficiency	0.000	0.823	0.177
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.830	0.169
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.830	0.169
E70.2 Disorders of tyrosine metabolism	0.000	0.830	0.169
E70.1 Other hyperphenylalaninaemias	0.000	0.830	0.169
E70.0 Classical phenylketonuria	0.000	0.830	0.169
E85.4 Organ-limited amyloidosis	0.000	0.833	0.166
E88 Other metabolic disorders	0.000	0.847	0.153
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.849	0.151
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.849	0.151
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.849	0.151
E74.2 Disorders of galactose metabolism	0.000	0.849	0.151
E74.1 Disorders of fructose metabolism	0.000	0.849	0.151
E73.9 Lactose intolerance, unspecified	0.000	0.868	0.132
E87.0 Hyperosmolality and hypernatraemia	0.000	0.877	0.123
E74.0 Glycogen storage disease	0.001	0.880	0.119
E87.3 Alkalosis	0.000	0.880	0.119
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.881	0.119
E70.3 Albinism	0.001	0.885	0.114
E87.7 Fluid overload	0.000	0.887	0.113
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.890	0.110
E88.3 Tumour lysis syndrome	0.000	0.891	0.109
E88.8 Other specified metabolic disorders	0.000	0.896	0.104
E88.9 Metabolic disorder, unspecified	0.000	0.897	0.103
E83 Disorders of mineral metabolism	0.000	0.909	0.091
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.914	0.085
E88.2 Lipomatosis, not elsewhere classified	0.001	0.933	0.067
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.934	0.066
E83.8 Other disorders of mineral metabolism	0.000	0.934	0.066
E83.2 Disorders of zinc metabolism	0.000	0.934	0.066
E83.0 Disorders of copper metabolism	0.000	0.934	0.066
E83.5 Disorders of calcium metabolism	0.000	0.937	0.063
E83.4 Disorders of magnesium metabolism	0.000	0.939	0.061
E10.3 With ophthalmic complications	0.000	0.955	0.045
E10 Insulin-dependent diabetes mellitus	0.000	0.957	0.042
E10.6 With other specified complications	0.000	0.961	0.039
E10.0 With coma	0.000	0.962	0.038
G45.9 Transient cerebral ischaemic attack, unspecified	0.036	0.964	0.000
E10.9 Without complications	0.000	0.964	0.036
E10.4 With neurological complications	0.000	0.966	0.034
E83.3 Disorders of phosphorus metabolism	0.000	0.966	0.033
E10.7 With multiple complications	0.000	0.969	0.031
E10.1 With ketoacidosis	0.000	0.969	0.031
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.969	0.031
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.970	0.030
E10-E14 Diabetes mellitus	0.000	0.970	0.030
E86 Volume depletion	0.000	0.970	0.030
E10.5 With peripheral circulatory complications	0.000	0.973	0.027
E87.2 Acidosis	0.000	0.974	0.026
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.025	0.975	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.025	0.975	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.023	0.977	0.000
M35.0 Sicca syndrome [Sjogren]	0.023	0.977	0.000
E10.8 With unspecified complications	0.000	0.977	0.023
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.977	0.023
E10.2 With renal complications	0.000	0.978	0.022
E12 Malnutrition-related diabetes mellitus	0.000	0.978	0.022
E13 Other specified diabetes mellitus	0.000	0.979	0.021
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.020	0.980	0.000
E40-E46 Malnutrition	0.000	0.980	0.020
M80 Osteoporosis with pathological fracture	0.019	0.981	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.019	0.981	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.019	0.981	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.018	0.982	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.018	0.982	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.018	0.982	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.018	0.982	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.018	0.982	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.018	0.982	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.018	0.982	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.018	0.982	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.983	0.017
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.983	0.017
E15 Nondiabetic hypoglycaemic coma	0.000	0.983	0.016
G43.9 Migraine, unspecified	0.016	0.984	0.000
E12.9 Without complications	0.000	0.984	0.016
E12.8 With unspecified complications	0.000	0.984	0.016
E12.7 With multiple complications	0.000	0.984	0.016
E12.6 With other specified complications	0.000	0.984	0.016
E12.5 With peripheral circulatory complications	0.000	0.984	0.016
E12.4 With neurological complications	0.000	0.984	0.016
E12.3 With ophthalmic complications	0.000	0.984	0.016
E12.2 With renal complications	0.000	0.984	0.016
E12.1 With ketoacidosis	0.000	0.984	0.016
E12.0 With coma	0.000	0.984	0.016
G56.2 Lesion of ulnar nerve	0.016	0.984	0.000
E13.3 With ophthalmic complications	0.000	0.985	0.015
E13.8 With unspecified complications	0.000	0.985	0.015
E13.7 With multiple complications	0.000	0.985	0.015
E13.6 With other specified complications	0.000	0.985	0.015
E13.5 With peripheral circulatory complications	0.000	0.985	0.015
E13.4 With neurological complications	0.000	0.985	0.015
E13.2 With renal complications	0.000	0.985	0.015
E13.1 With ketoacidosis	0.000	0.985	0.015
E13.0 With coma	0.000	0.985	0.015
G43 Migraine	0.015	0.985	0.000
G56.8 Other mononeuropathies of upper limb	0.015	0.985	0.000
E65-E68 Obesity and other hyperalimentation	0.000	0.985	0.015
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.986	0.014
E45 Retarded development following protein-energy malnutrition	0.000	0.986	0.014
E43 Unspecified severe protein-energy malnutrition	0.000	0.986	0.014
E42 Marasmic kwashiorkor	0.000	0.986	0.014
E41 Nutritional marasmus	0.000	0.986	0.014
E40 Kwashiorkor	0.000	0.986	0.014
M80.5 Idiopathic osteoporosis with pathological fracture	0.014	0.986	0.000
G56.3 Lesion of radial nerve	0.014	0.986	0.000
G56 Mononeuropathies of upper limb	0.014	0.986	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.014	0.986	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.014	0.986	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.014	0.986	0.000
E13.9 Without complications	0.000	0.986	0.014
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.014	0.986	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.014	0.986	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.014	0.986	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.014	0.986	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.014	0.986	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.014	0.986	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.014	0.986	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.014	0.986	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.014	0.986	0.000
G45.0 Vertebro-basilar artery syndrome	0.014	0.986	0.000
G40-G47 Episodic and paroxysmal disorders	0.014	0.986	0.000
G40.9 Epilepsy, unspecified	0.014	0.986	0.000
M80.8 Other osteoporosis with pathological fracture	0.013	0.986	0.000
G43.8 Other migraine	0.013	0.986	0.000
G45.2 Multiple and bilateral precerebral artery syndromes	0.013	0.987	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.987	0.013
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.987	0.013
E16.4 Abnormal secretion of gastrin	0.000	0.987	0.013
E16.3 Increased secretion of glucagon	0.000	0.987	0.013
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.013	0.987	0.000
E14 Unspecified diabetes mellitus	0.000	0.987	0.013
E83.1 Disorders of iron metabolism	0.000	0.987	0.012
E16.1 Other hypoglycaemia	0.000	0.988	0.012
C44.5 Skin of trunk	0.012	0.988	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.012	0.988	0.000
E46 Unspecified protein-energy malnutrition	0.000	0.988	0.012
G40 Epilepsy	0.012	0.988	0.000
Q60.0 Renal agenesis, unilateral	0.012	0.988	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.011	0.989	0.000
E65 Localised adiposity	0.000	0.989	0.011
R21 Rash and other nonspecific skin eruption	0.000	0.989	0.011
G45.1 Carotid artery syndrome (hemispheric)	0.011	0.989	0.000
G43.2 Status migrainosus	0.011	0.989	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.011	0.989	0.000
E14.3 With ophthalmic complications	0.000	0.989	0.011
E67 Other hyperalimentation	0.000	0.989	0.011
E68 Sequelae of hyperalimentation	0.000	0.989	0.011
G56.1 Other lesions of median nerve	0.011	0.989	0.000
G45.4 Transient global amnesia	0.011	0.989	0.000
E44.1 Mild protein-energy malnutrition	0.000	0.989	0.010
E44.0 Moderate protein-energy malnutrition	0.000	0.989	0.010
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.010	0.989	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.010	0.989	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.010	0.989	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.010	0.989	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.010	0.989	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.010	0.989	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.010	0.989	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.010	0.989	0.000
G43.0 Migraine without aura [common migraine]	0.010	0.989	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.010	0.990	0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.010	0.990	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.010	0.990	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.010	0.990	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.010	0.990	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.010	0.990	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.010	0.990	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.010	0.990	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.010	0.990	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.010	0.990	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.010	0.990	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.010	0.990	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.010	0.990	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.010	0.990	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.010	0.990	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.010	0.990	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.010	0.990	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.010	0.990	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.010	0.990	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.010	0.990	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.010	0.990	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.010	0.990	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.010	0.990	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.010	0.990	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.010	0.990	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.010	0.990	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.010	0.990	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.010	0.990	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.010	0.990	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.010	0.990	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.010	0.990	0.000
G43.3 Complicated migraine	0.010	0.990	0.000
Z75.1 Person awaiting admission to adequate facility elsewhere	0.010	0.990	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.010	0.990	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.010	0.990	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.010	0.990	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.010	0.990	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.010	0.990	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.010	0.990	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.010	0.990	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.010	0.990	0.000
E14.2 Withrenal complications	0.000	0.990	0.010
G44 Other headache syndromes	0.010	0.990	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.010	0.990	0.000
E14.6 With other specified complications	0.000	0.990	0.009
G45.3 Amaurosis fugax	0.009	0.991	0.000
E14.7 With multiple complications	0.000	0.991	0.009
E14.0 With coma	0.000	0.991	0.009
E04.2 Non-toxic multinodular goitre	0.009	0.991	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.009	0.991	0.000
G43.1 Migraine with aura [classical migraine]	0.009	0.991	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.009	0.991	0.000
G56.4 Causalgia	0.009	0.991	0.000
E14.5 With peripheral circulatory complications	0.000	0.991	0.009
G56.9 Mononeuropathy of upper limb, unspecified	0.009	0.991	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.009	0.991	0.000
E14.8 With unspecified complications	0.000	0.991	0.009
E14.4 With neurological complications	0.000	0.991	0.009
G44.0 Cluster headache syndrome	0.009	0.991	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.008	0.991	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.008	0.992	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.008	0.992	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.008	0.992	0.000
G41 Status epilepticus	0.008	0.992	0.000
G40.8 Other epilepsy	0.008	0.992	0.000
E67.8 Other specified hyperalimentation	0.000	0.992	0.008
E67.3 Hypervitaminosis D	0.000	0.992	0.008
E67.2 Megavitamin-B6 syndrome	0.000	0.992	0.008
E67.1 Hypercarotenaemia	0.000	0.992	0.008
E67.0 Hypervitaminosis A	0.000	0.992	0.008
G44.1 Vascular headache, not elsewhere classified	0.008	0.992	0.000
E50-E64 Other nutritional deficiencies	0.000	0.992	0.008
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.008	0.992	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.008	0.992	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.007	0.992	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.007	0.992	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.007	0.992	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.007	0.992	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.007	0.992	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.007	0.992	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.007	0.992	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.007	0.992	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.007	0.992	0.000
M07.3 Other psoriatic arthropathies	0.008	0.992	0.000
G44.4 Drug-induced headache, not elsewhere classified	0.007	0.992	0.000
G44.8 Other specified headache syndromes	0.007	0.993	0.000
G46.8 Other vascular syndromes of brain in cerebrovascular diseases	0.007	0.993	0.000
G46.6 Pure sensory lacunar syndrome	0.007	0.993	0.000
G46.5 Pure motor lacunar syndrome	0.007	0.993	0.000
G46.4 Cerebellar stroke syndrome	0.007	0.993	0.000
G46.3 Brain stem stroke syndrome	0.007	0.993	0.000
G46.2 Posterior cerebral artery syndrome	0.007	0.993	0.000
G46.1 Anterior cerebral artery syndrome	0.007	0.993	0.000
G46.0 Middle cerebral artery syndrome	0.007	0.993	0.000
K31.1 Adult hypertrophic pyloric stenosis	0.007	0.993	0.000
S82.20 Fracture of shaft of tibia (closed)	0.007	0.993	0.000
G44.3 Chronic posttraumatic headache	0.007	0.993	0.000
G46.7 Other lacunar syndromes	0.007	0.993	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.993	0.007
E14.1 With ketoacidosis	0.000	0.993	0.006
G40.7 Petit mal, unspecified, without grand mal seizures	0.006	0.993	0.000
Q60.2 Renal agenesis, unspecified	0.007	0.993	0.000
G40.5 Special epileptic syndromes	0.006	0.993	0.000
G41.8 Other status epilepticus	0.006	0.993	0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.000	0.994	0.006
M80-M85 Disorders of bone density and structure	0.006	0.994	0.000
H90.5 Sensorineural hearing loss, unspecified	0.000	0.994	0.006
Q60.6 Potter's syndrome	0.006	0.994	0.000
Q60.5 Renal hypoplasia, unspecified	0.006	0.994	0.000
Q60.4 Renal hypoplasia, bilateral	0.006	0.994	0.000
Q60.3 Renal hypoplasia, unilateral	0.006	0.994	0.000
Q60.1 Renal agenesis, bilateral	0.006	0.994	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.006	0.994	0.000
Q23 Congenital malformations of aortic and mitral valves	0.006	0.994	0.000
H90.0 Conductive hearing loss, bilateral	0.000	0.994	0.006
E56 Other vitamin deficiencies	0.000	0.994	0.006
M07.34 Other psoriatic arthropathies (Hand)	0.006	0.994	0.000
H90 Conductive and sensorineural hearing loss	0.000	0.994	0.006
Q23.1 Congenital insufficiency of aortic valve	0.006	0.994	0.000
G41.1 Petit mal status epilepticus	0.006	0.994	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.006	0.994	0.000
M84.06 Malunion of fracture (Lower leg)	0.006	0.994	0.000
G41.0 Grand mal status epilepticus	0.006	0.994	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.994	0.006
E50 Vitamin A deficiency	0.000	0.994	0.006
E60 Dietary zinc deficiency	0.000	0.994	0.006
E59 Dietary selenium deficiency	0.000	0.994	0.006
E54 Ascorbic acid deficiency	0.000	0.994	0.006
E52 Niacin deficiency [pellagra]	0.000	0.994	0.006
G41.2 Complex partial status epilepticus	0.006	0.994	0.000
Q25 Congenital malformations of great arteries	0.006	0.994	0.000
M84.0 Malunion of fracture	0.006	0.994	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.006	0.994	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.006	0.994	0.000
M07.38 Other psoriatic arthropathies (Other)	0.006	0.994	0.000
E63 Other nutritional deficiencies	0.000	0.994	0.006
H90.2 Conductive hearing loss, unspecified	0.000	0.994	0.006
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.000	0.994	0.006
Q24 Other congenital malformations of heart	0.006	0.994	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.006	0.994	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.000	0.994	0.006
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.005	0.994	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.005	0.994	0.000
Q60-Q64 Congenital malformations of the urinary system	0.005	0.994	0.000
H36.0 Diabetic retinopathy	0.000	0.994	0.006
M06.3 Rheumatoid nodule	0.005	0.995	0.000
E58 Dietary calcium deficiency	0.000	0.995	0.005
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.005	0.995	0.000
Z87.0 Personal history of diseases of the respiratory system	0.000	0.995	0.005
M06.34 Rheumatoid nodule (Hand)	0.005	0.995	0.000
H90.3 Sensorineural hearing loss, bilateral	0.000	0.995	0.005
M84 Disorders of continuity of bone	0.005	0.995	0.000
Q26 Congenital malformations of great veins	0.005	0.995	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.005	0.995	0.000
Q50-Q56 Congenital malformations of genital organs	0.005	0.995	0.000
Q23.0 Congenital stenosis of aortic valve	0.005	0.995	0.000
E51 Thiamine deficiency	0.000	0.995	0.005
Q25.3 Stenosis of aorta	0.005	0.995	0.000
Q25.0 Patent ductus arteriosus	0.005	0.995	0.000
Q74 Other congenital malformations of limb(s)	0.005	0.995	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.005	0.995	0.000
Q22.5 Ebstein's anomaly	0.005	0.995	0.000
M84.2 Delayed union of fracture	0.005	0.995	0.000
M84.03 Malunion of fracture (Forearm)	0.005	0.995	0.000
E56.1 Deficiency of vitamin K	0.000	0.995	0.005
M07 Psoriatic and enteropathic arthropathies	0.005	0.995	0.000
Q53 Undescended testicle	0.005	0.995	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.005	0.995	0.000
M83 Adult osteomalacia	0.005	0.995	0.000
Q24.4 Congenital subaortic stenosis	0.005	0.995	0.000
M84.01 Malunion of fracture (Shoulder region)	0.005	0.995	0.000
M06 Other rheumatoid arthritis	0.005	0.995	0.000
Q23.3 Congenital mitral insufficiency	0.005	0.995	0.000
O03.4 Incomplete, without complication	0.005	0.995	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.005	0.995	0.000
M84.26 Delayed union of fracture (Lower leg)	0.005	0.995	0.000
M84.08 Malunion of fracture (Other)	0.005	0.995	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.005	0.995	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.005	0.995	0.000
Q23.4 Hypoplastic left heart syndrome	0.005	0.995	0.000
Q23.2 Congenital mitral stenosis	0.005	0.995	0.000
M85 Other disorders of bone density and structure	0.005	0.995	0.000
S22.40 Multiple fractures of ribs (closed)	0.000	0.995	0.005
M06.0 Seronegative rheumatoid arthritis	0.005	0.995	0.000
Q25.6 Stenosis of pulmonary artery	0.005	0.995	0.000
Q74.1 Congenital malformation of knee	0.005	0.995	0.000
H21.8 Other specified disorders of iris and ciliary body	0.000	0.995	0.005
E56.9 Vitamin deficiency, unspecified	0.000	0.995	0.004
E56.8 Deficiency of other vitamins	0.000	0.995	0.004
E56.0 Deficiency of vitamin E	0.000	0.995	0.004
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.995	0.005
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.005	0.995	0.000
M84.04 Malunion of fracture (Hand)	0.005	0.995	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.005	0.995	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.005	0.995	0.000
Q64 Other congenital malformations of urinary system	0.004	0.995	0.000
E00-E07 Disorders of thyroid gland	0.001	0.995	0.004
M07.36 Other psoriatic arthropathies (Lower leg)	0.004	0.995	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.005	0.995	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.004	0.995	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.004	0.995	0.000
Q52 Other congenital malformations of female genitalia	0.004	0.995	0.000
E50.9 Vitamin A deficiency, unspecified	0.000	0.995	0.004
E50.8 Other manifestations of vitamin A deficiency	0.000	0.995	0.004
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.995	0.004
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.995	0.004
E50.5 Vitamin A deficiency with night blindness	0.000	0.995	0.004
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.995	0.004
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.995	0.004
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.995	0.004
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.995	0.004
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.995	0.004
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.995	0.004
E64.8 Sequelae of other nutritional deficiencies	0.000	0.995	0.004
E64.3 Sequelae of rickets	0.000	0.995	0.004
E64.2 Sequelae of vitamin C deficiency	0.000	0.995	0.004
E64.1 Sequelae of vitamin A deficiency	0.000	0.995	0.004
E64.0 Sequelae of protein-energy malnutrition	0.000	0.995	0.004
Q51 Congenital malformations of uterus and cervix	0.004	0.995	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.995	0.005
Q25.9 Congenital malformation of great arteries, unspecified	0.004	0.995	0.000
Q25.8 Other congenital malformations of great arteries	0.004	0.995	0.000
Q25.5 Atresia of pulmonary artery	0.004	0.995	0.000
Q25.2 Atresia of aorta	0.004	0.995	0.000
Q21 Congenital malformations of cardiac septa	0.004	0.995	0.000
M85.2 Hyperostosis of skull	0.004	0.996	0.000
Q25.1 Coarctation of aorta	0.004	0.996	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.004	0.996	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.996	0.004
Q22.1 Congenital pulmonary valve stenosis	0.004	0.996	0.000
Q53.9 Undescended testicle, unspecified	0.004	0.996	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.004	0.996	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.004	0.996	0.000
M84.09 Malunion of fracture (Site unspecified)	0.004	0.996	0.000
M84.00 Malunion of fracture (Multiple sites)	0.004	0.996	0.000
Q24.5 Malformation of coronary vessels	0.004	0.996	0.000
Q55 Other congenital malformations of male genital organs	0.004	0.996	0.000
Q24.0 Dextrocardia	0.004	0.996	0.000
Z75 Problems related to medical facilities and other health care	0.004	0.996	0.000
E63.8 Other specified nutritional deficiencies	0.000	0.996	0.004
E63.1 Imbalance of constituents of food intake	0.000	0.996	0.004
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.996	0.004
M82 Osteoporosis in diseases classified elsewhere	0.004	0.996	0.000
M06.9 Rheumatoid arthritis, unspecified	0.004	0.996	0.000
Q53.2 Undescended testicle, bilateral	0.004	0.996	0.000
E61 Deficiency of other nutrient elements	0.000	0.996	0.004
E55 Vitamin D deficiency	0.000	0.996	0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations