TreeWAS – Variant ID: rs10168349

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E04.2 Non-toxic multinodular goitre	0.000	0.911	0.089
E04 Other non-toxic goitre	0.000	0.957	0.043
E04.1 Non-toxic single thyroid nodule	0.000	0.962	0.038
E04.8 Other specified non-toxic goitre	0.000	0.969	0.031
E04.9 Non-toxic goitre, unspecified	0.000	0.970	0.030
R04.2 Haemoptysis	0.000	0.977	0.023
E04.0 Non-toxic diffuse goitre	0.000	0.982	0.017
E27 Other disorders of adrenal gland	0.013	0.987	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.013	0.987	0.000
G55.2 Nerve root and plexus compressions in spondylosis	0.000	0.988	0.012
E27.1 Primary adrenocortical insufficiency	0.012	0.988	0.000
E27.2 Addisonian crisis	0.011	0.989	0.000
R04 Haemorrhage from respiratory passages	0.000	0.989	0.011
E27.3 Drug-induced adrenocortical insufficiency	0.010	0.989	0.000
E27.8 Other specified disorders of adrenal gland	0.011	0.989	0.000
E23.2 Diabetes insipidus	0.010	0.990	0.000
E23 Hypofunction and other disorders of pituitary gland	0.010	0.990	0.000
R04.8 Haemorrhage from other sites in respiratory passages	0.000	0.990	0.010
E27.5 Adrenomedullary hyperfunction	0.009	0.991	0.000
E27.0 Other adrenocortical overactivity	0.009	0.991	0.000
E23.0 Hypopituitarism	0.009	0.991	0.000
E23.6 Other disorders of pituitary gland	0.009	0.991	0.000
R04.9 Haemorrhage from respiratory passages, unspecified	0.000	0.992	0.008
E20-E35 Disorders of other endocrine glands	0.008	0.992	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.008	0.992	0.000
E23.7 Disorder of pituitary gland, unspecified	0.007	0.993	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.007	0.993	0.000
E23.1 Drug-induced hypopituitarism	0.007	0.993	0.000
R04.0 Epistaxis	0.000	0.993	0.007
R04.1 Haemorrhage from throat	0.000	0.993	0.007
M25.47 Effusion of joint (Ankle and foot)	0.007	0.993	0.000
E24 Cushing's syndrome	0.007	0.993	0.000
E26 Hyperaldosteronism	0.007	0.993	0.000
E27.9 Disorder of adrenal gland, unspecified	0.006	0.993	0.000
G55.3 Nerve root and plexus compressions in other dorsopathies	0.000	0.993	0.007
C77.1 Intrathoracic lymph nodes	0.006	0.994	0.000
E25 Adrenogenital disorders	0.006	0.994	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.006	0.994	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.006	0.994	0.000
E32 Diseases of thymus	0.006	0.994	0.000
E31 Polyglandular dysfunction	0.006	0.994	0.000
E30 Disorders of puberty, not elsewhere classified	0.006	0.994	0.000
E20 Hypoparathyroidism	0.006	0.994	0.000
E26.0 Primary hyperaldosteronism	0.006	0.994	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.000	0.994	0.006
M05.9 Seropositive rheumatoid arthritis, unspecified	0.006	0.994	0.000
E24.2 Drug-induced Cushing's syndrome	0.006	0.994	0.000
E29 Testicular dysfunction	0.006	0.994	0.000
E24.8 Other Cushing's syndrome	0.005	0.995	0.000
E24.9 Cushing's syndrome, unspecified	0.005	0.995	0.000
E22 Hyperfunction of pituitary gland	0.005	0.995	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.005	0.995	0.000
E24.3 Ectopic ACTH syndrome	0.005	0.995	0.000
E24.1 Nelson's syndrome	0.005	0.995	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.005	0.995	0.000
E26.8 Other hyperaldosteronism	0.005	0.995	0.000
E26.1 Secondary hyperaldosteronism	0.005	0.995	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.005	0.995	0.000
G55.0 Nerve root and plexus compressions in neoplastic disease	0.000	0.995	0.005
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.995	0.005
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.005	0.995	0.000
E24.0 Pituitary-dependent Cushing's disease	0.005	0.995	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.995	0.005
E26.9 Hyperaldosteronism, unspecified	0.005	0.995	0.000
Z43.1 Attention to gastrostomy	0.000	0.995	0.005
E25.9 Adrenogenital disorder, unspecified	0.005	0.995	0.000
E25.8 Other adrenogenital disorders	0.005	0.995	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.005	0.995	0.000
J31.0 Chronic rhinitis	0.005	0.995	0.000
S00.0 Superficial injury of scalp	0.000	0.995	0.005
E30.9 Disorder of puberty, unspecified	0.004	0.995	0.000
E30.8 Other disorders of puberty	0.004	0.995	0.000
E30.1 Precocious puberty	0.004	0.995	0.000
E30.0 Delayed puberty	0.004	0.995	0.000
E31.9 Polyglandular dysfunction, unspecified	0.004	0.995	0.000
E31.8 Other polyglandular dysfunction	0.004	0.995	0.000
E31.1 Polyglandular hyperfunction	0.004	0.995	0.000
E31.0 Autoimmune polyglandular failure	0.004	0.995	0.000
E32.9 Disease of thymus, unspecified	0.004	0.995	0.000
E32.8 Other diseases of thymus	0.004	0.995	0.000
E32.1 Abscess of thymus	0.004	0.995	0.000
E32.0 Persistent hyperplasia of thymus	0.004	0.995	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.004	0.995	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.004	0.995	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.004	0.995	0.000
E22.0 Acromegaly and pituitary gigantism	0.005	0.995	0.000
E20.8 Other hypoparathyroidism	0.004	0.995	0.000
E20.1 Pseudohypoparathyroidism	0.004	0.995	0.000
E20.0 Idiopathic hypoparathyroidism	0.004	0.995	0.000
M31.6 Other giant cell arteritis	0.005	0.995	0.000
E20.9 Hypoparathyroidism, unspecified	0.004	0.995	0.000
K31.9 Disease of stomach and duodenum, unspecified	0.000	0.996	0.004
E34 Other endocrine disorders	0.004	0.996	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.004	0.996	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.004	0.996	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.004	0.996	0.000
M94.88 Other specified disorders of cartilage (Other)	0.004	0.996	0.000
E29.9 Testicular dysfunction, unspecified	0.004	0.996	0.000
E29.8 Other testicular dysfunction	0.004	0.996	0.000
E29.0 Testicular hyperfunction	0.004	0.996	0.000
J31.2 Chronic pharyngitis	0.004	0.996	0.000
T82.1 Mechanical complication of cardiac electronic device	0.000	0.996	0.004
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.004	0.996	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.004	0.996	0.000
Z43.0 Attention to tracheostomy	0.000	0.996	0.004
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.000	0.996	0.004
E22.8 Other hyperfunction of pituitary gland	0.004	0.996	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.996	0.004
K25.0 Acute with haemorrhage	0.000	0.996	0.004
E29.1 Testicular hypofunction	0.004	0.996	0.000
M94.8 Other specified disorders of cartilage	0.004	0.996	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.004	0.996	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.000	0.996	0.004
E34.9 Endocrine disorder, unspecified	0.004	0.996	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.004	0.996	0.000
E28 Ovarian dysfunction	0.003	0.996	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.003	0.996	0.000
E34.5 Androgen resistance syndrome	0.003	0.997	0.000
E34.4 Constitutional tall stature	0.003	0.997	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.003	0.997	0.000
E34.1 Other hypersecretion of intestinal hormones	0.003	0.997	0.000
W55.0 Home	0.003	0.997	0.000
E34.3 Short stature, not elsewhere classified	0.003	0.997	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.003	0.997	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.000	0.997	0.003
T82.3 Mechanical complication of other vascular grafts	0.000	0.997	0.003
T82.0 Mechanical complication of heart valve prosthesis	0.000	0.997	0.003
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.003	0.997	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.997	0.003
K13.0 Diseases of lips	0.000	0.997	0.003
N81.1 Cystocele	0.003	0.997	0.000
K82.1 Hydrops of gallbladder	0.003	0.997	0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.003	0.997	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.000	0.997	0.003
H50.1 Divergent concomitant strabismus	0.003	0.997	0.000
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.003	0.997	0.000
C45.9 Mesothelioma, unspecified	0.003	0.997	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.003	0.997	0.000
N80.0 Endometriosis of uterus	0.003	0.997	0.000
M94.84 Other specified disorders of cartilage (Hand)	0.003	0.997	0.000
M94.83 Other specified disorders of cartilage (Forearm)	0.003	0.997	0.000
M94.82 Other specified disorders of cartilage (Upper arm)	0.003	0.997	0.000
M94.81 Other specified disorders of cartilage (Shoulder region)	0.003	0.997	0.000
M94.80 Other specified disorders of cartilage (Multiple sites)	0.003	0.997	0.000
J31.1 Chronic nasopharyngitis	0.003	0.997	0.000
M05 Seropositive rheumatoid arthritis	0.003	0.997	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.003	0.997	0.000
Z43.5 Attention to cyctostomy	0.000	0.997	0.003
W29.9 Unspecified place	0.000	0.997	0.003
R21 Rash and other nonspecific skin eruption	0.000	0.997	0.003
E28.9 Ovarian dysfunction, unspecified	0.003	0.997	0.000
E28.8 Other ovarian dysfunction	0.003	0.997	0.000
E28.1 Androgen excess	0.003	0.997	0.000
E28.0 Oestrogen excess	0.003	0.997	0.000
T79.8 Other early complications of trauma	0.000	0.997	0.003
M25.45 Effusion of joint (Pelvic region and thigh)	0.003	0.997	0.000
K85.9 Acute pancreatitis, unspecified	0.000	0.997	0.003
M94.89 Other specified disorders of cartilage (Site unspecified)	0.003	0.997	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.003	0.997	0.000
Z43 Attention to artificial openings	0.000	0.997	0.003
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.000	0.997	0.003
C45.7 Mesothelioma of other sites	0.003	0.997	0.000
E34.8 Other specified endocrine disorders	0.002	0.997	0.000
H80.9 Otosclerosis, unspecified	0.000	0.997	0.003
T20.0 Burn of unspecified degree of head and neck	0.003	0.997	0.000
C45.0 Mesothelioma of pleura	0.003	0.997	0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.000	0.997	0.002
M90.7 Fracture of bone in neoplastic disease	0.000	0.997	0.003
C45 Mesothelioma	0.003	0.997	0.000
E34.0 Carcinoid syndrome	0.002	0.997	0.000
M05.1 Rheumatoid lung disease	0.002	0.997	0.000
M25.4 Effusion of joint	0.003	0.997	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.003	0.997	0.000
T23.3 Burn of third degree of wrist and hand	0.003	0.997	0.000
T20 Burn and corrosion of head and neck	0.003	0.997	0.000
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis	0.002	0.997	0.000
T20.1 Burn of first degree of head and neck	0.002	0.997	0.000
B00.1 Herpesviral vesicular dermatitis	0.002	0.998	0.000
E21.4 Other specified disorders of parathyroid gland	0.002	0.998	0.000
E22.1 Hyperprolactinaemia	0.002	0.998	0.001
M05.8 Other seropositive rheumatoid arthritis	0.002	0.998	0.000
T88.5 Other complications of anaesthesia	0.000	0.998	0.002
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.002	0.998	0.000
M05.2 Rheumatoid vasculitis	0.002	0.998	0.000
M05.0 Felty's syndrome	0.002	0.998	0.000
M25.42 Effusion of joint (Upper arm)	0.002	0.998	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.000	0.998	0.002
M96.0 Pseudarthrosis after fusion or arthrodesis	0.002	0.998	0.000
T79.6 Traumatic ischaemia of muscle	0.000	0.998	0.002
B02.2 Zoster with other nervous system involvement	0.002	0.998	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.000	0.998	0.002
M25.44 Effusion of joint (Hand)	0.002	0.998	0.000
J32.9 Chronic sinusitis, unspecified	0.002	0.998	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.002	0.998	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.002	0.998	0.000
H20.8 Other iridocyclitis	0.000	0.998	0.002
T20.2 Burn of second degree of head and neck	0.002	0.998	0.000
Z43.9 Attention to unspecified artificial opening	0.000	0.998	0.002
Z43.7 Attention to artificial vagina	0.000	0.998	0.002
M94 Other disorders of cartilage	0.002	0.998	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.002	0.998	0.000
R85.5 Abnormal microbiological findings	0.002	0.998	0.000
Z49.0 Preparatory care for dialysis	0.000	0.998	0.002
E21.2 Other hyperparathyroidism	0.002	0.998	0.000
K00.6 Disturbances in tooth eruption	0.002	0.998	0.000
K26.7 Chronic without haemorrhage or perforation	0.000	0.998	0.002
C45.2 Mesothelioma of pericardium	0.002	0.998	0.000
C45.1 Mesothelioma of peritoneum	0.002	0.998	0.000
M93.9 Osteochondropathy, unspecified	0.002	0.998	0.000
S12.2 Fracture of other specified cervical vertebra	0.002	0.998	0.000
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.000	0.998	0.002
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.000	0.998	0.002
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.000	0.998	0.002
M90.74 Fracture of bone in neoplastic disease (Hand)	0.000	0.998	0.002
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.000	0.998	0.002
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.000	0.998	0.002
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.000	0.998	0.002
B00 Herpesviral [herpes simplex] infections	0.002	0.998	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.002	0.998	0.000
E89.3 Postprocedural hypopituitarism	0.002	0.998	0.000
M05.18 Rheumatoid lung disease (Other)	0.002	0.998	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.002	0.998	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.002	0.998	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.002	0.998	0.000
M05.14 Rheumatoid lung disease (Hand)	0.002	0.998	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.002	0.998	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.002	0.998	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.002	0.998	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.002	0.998	0.000
T18.1 Foreign body in oesophagus	0.000	0.998	0.002
T40.4 Other synthetic narcotics	0.002	0.998	0.000
M25.49 Effusion of joint (Site unspecified)	0.002	0.998	0.000
M25.48 Effusion of joint (Other)	0.002	0.998	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.002	0.998	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.002	0.998	0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.000	0.998	0.002
T20.7 Corrosion of third degree of head and neck	0.002	0.998	0.000
T20.6 Corrosion of second degree of head and neck	0.002	0.998	0.000
T20.5 Corrosion of first degree of head and neck	0.002	0.998	0.000
T20.4 Corrosion of unspecified degree of head and neck	0.002	0.998	0.000
T20.3 Burn of third degree of head and neck	0.002	0.998	0.000
T23 Burn and corrosion of wrist and hand	0.002	0.998	0.000
E28.3 Primary ovarian failure	0.002	0.998	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.000	0.998	0.002
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.002	0.998	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.002	0.998	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.002	0.998	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.002	0.998	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.002	0.998	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.002	0.998	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.002	0.998	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.002	0.998	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.002	0.998	0.000
B00.5 Herpesviral ocular disease	0.002	0.998	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.000	0.998	0.002
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.998	0.002
Z49.2 Other dialysis	0.000	0.998	0.002
K91.3 Postoperative intestinal obstruction	0.000	0.998	0.002
R06.2 Wheezing	0.000	0.998	0.002
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
M05.09 Felty's syndrome (Site unspecified)	0.002	0.998	0.000
M05.08 Felty's syndrome (Other)	0.002	0.998	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.002	0.998	0.000
M05.06 Felty's syndrome (Lower leg)	0.002	0.998	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.002	0.998	0.000
M05.04 Felty's syndrome (Hand)	0.002	0.998	0.000
M05.03 Felty's syndrome (Forearm)	0.002	0.998	0.000
M05.02 Felty's syndrome (Upper arm)	0.002	0.998	0.000
M05.01 Felty's syndrome (Shoulder region)	0.002	0.998	0.000
M05.00 Felty's syndrome (Multiple sites)	0.002	0.998	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.002	0.998	0.000
M05.28 Rheumatoid vasculitis (Other)	0.002	0.998	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.002	0.998	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.002	0.998	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.002	0.998	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.002	0.998	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.002	0.998	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.002	0.998	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.002	0.998	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.002	0.998	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.002	0.998	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.002	0.998	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.002	0.998	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.002	0.998	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.002	0.998	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.002	0.998	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.002	0.998	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.002	0.998	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.002	0.998	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.002	0.998	0.000
Z49.1 Extracorporeal dialysis	0.000	0.998	0.002
W55 Bitten or struck by other mammals	0.002	0.998	0.000
F41.1 Generalised anxiety disorder	0.000	0.998	0.002
Z43.8 Attention to other artificial openings	0.000	0.998	0.002
M25.43 Effusion of joint (Forearm)	0.002	0.998	0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.000	0.998	0.002
Z43.3 Attention to colostomy	0.000	0.998	0.002
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
M93 Other osteochondropathies	0.002	0.998	0.000
M94.3 Chondrolysis	0.002	0.998	0.000
M94.1 Relapsing polychondritis	0.002	0.998	0.000
M25.41 Effusion of joint (Shoulder region)	0.002	0.998	0.000
K82.4 Cholesterolosis of gallbladder	0.002	0.998	0.000
Z49 Care involving dialysis	0.000	0.998	0.002
L29.0 Pruritus ani	0.000	0.998	0.002
S12.21 Fracture of other specified cervical vertebra (open)	0.002	0.998	0.000
I30.9 Acute pericarditis, unspecified	0.000	0.998	0.002
M94.2 Chondromalacia	0.002	0.998	0.000
T23.2 Burn of second degree of wrist and hand	0.002	0.998	0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.002	0.998	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.002	0.998	0.000
B00.8 Other forms of herpesviral infection	0.002	0.998	0.000
B00.7 Disseminated herpesviral disease	0.002	0.998	0.000
B00.3 Herpesviral meningitis	0.002	0.998	0.000
B00.0 Eczema herpeticum	0.002	0.998	0.000
E21.3 Hyperparathyroidism, unspecified	0.002	0.998	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
W55.4 Street and highway	0.002	0.998	0.000
R85.7 Abnormal histological findings	0.002	0.998	0.000
S12.7 Multiple fractures of cervical spine	0.002	0.998	0.000
E00-E07 Disorders of thyroid gland	0.000	0.998	0.002
M94.0 Chondrocostal junction syndrome [Tietze]	0.002	0.998	0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T23.7 Corrosion of third degree of wrist and hand	0.002	0.998	0.000
T23.6 Corrosion of second degree of wrist and hand	0.002	0.998	0.000
T23.5 Corrosion of first degree of wrist and hand	0.002	0.998	0.000
T23.4 Corrosion of unspecified degree of wrist and hand	0.002	0.998	0.000
M25.40 Effusion of joint (Multiple sites)	0.002	0.998	0.000
E28.2 Polycystic ovarian syndrome	0.002	0.998	0.000
B02.8 Zoster with other complications	0.002	0.998	0.000
K11.5 Sialolithiasis	0.002	0.998	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.002	0.998	0.000
K82.2 Perforation of gallbladder	0.002	0.998	0.000
T79.9 Unspecified early complication of trauma	0.000	0.998	0.002
T79.4 Traumatic shock	0.000	0.998	0.002
T79.2 Traumatic secondary and recurrent haemorrhage	0.000	0.998	0.002
T79.1 Fat embolism (traumatic)	0.000	0.998	0.002
T79.0 Air embolism (traumatic)	0.000	0.998	0.002
M65.83 Other synovitis and tenosynovitis (Forearm)	0.002	0.998	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.002	0.998	0.000
M93.1 Kienbock's disease of adults	0.002	0.998	0.000
T88.9 Complication of surgical and medical care, unspecified	0.000	0.998	0.002
W55.9 Unspecified place	0.002	0.998	0.000
W55.5 Trade and service area	0.002	0.998	0.000
W55.6 Industrial and construction area	0.002	0.998	0.000
W55.3 Sports and athletics area	0.002	0.998	0.000
W55.2 School, other institution and public administrative area	0.002	0.998	0.000
W55.1 Residential institution	0.002	0.998	0.000
M94.9 Disorder of cartilage, unspecified	0.001	0.998	0.000
Z43.4 Attention to other artificial openings of digestive tract	0.000	0.998	0.002
C21.0 Anus, unspecified	0.000	0.998	0.002
R07.0 Pain in throat	0.000	0.998	0.002
R85.8 Other abnormal findings	0.002	0.998	0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
W55.7 Farm	0.002	0.998	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.000	0.998	0.002
M93.8 Other specified osteochondropathies	0.001	0.998	0.000
M93.2 Osteochondritis dissecans	0.001	0.998	0.000
M93.0 Slipped upper femoral epiphysis (nontraumatic)	0.001	0.998	0.000
T79.7 Traumatic subcutaneous emphysema	0.000	0.998	0.002
T79.5 Traumatic anuria	0.000	0.998	0.002
M94.19 Relapsing polychondritis (Site unspecified)	0.001	0.998	0.000
M94.18 Relapsing polychondritis (Other)	0.001	0.998	0.000
M94.17 Relapsing polychondritis (Ankle and foot)	0.001	0.998	0.000
M94.16 Relapsing polychondritis (Lower leg)	0.001	0.998	0.000
M94.15 Relapsing polychondritis (Pelvic region and thigh)	0.001	0.998	0.000
M94.14 Relapsing polychondritis (Hand)	0.001	0.998	0.000
M94.13 Relapsing polychondritis (Forearm)	0.001	0.998	0.000
M94.12 Relapsing polychondritis (Upper arm)	0.001	0.998	0.000
M94.11 Relapsing polychondritis (Shoulder region)	0.001	0.998	0.000
M94.10 Relapsing polychondritis (Multiple sites)	0.001	0.998	0.000
M94.39 Chondrolysis (Site unspecified)	0.001	0.998	0.000
M94.38 Chondrolysis (Other)	0.001	0.998	0.000
M94.37 Chondrolysis (Ankle and foot)	0.001	0.998	0.000
M94.36 Chondrolysis (Lower leg)	0.001	0.998	0.000
M94.35 Chondrolysis (Pelvic region and thigh)	0.001	0.998	0.000
M94.34 Chondrolysis (Hand)	0.001	0.998	0.000
M94.33 Chondrolysis (Forearm)	0.001	0.998	0.000
M94.32 Chondrolysis (Upper arm)	0.001	0.998	0.000
M94.31 Chondrolysis (Shoulder region)	0.001	0.998	0.000
M94.30 Chondrolysis (Multiple sites)	0.001	0.998	0.000
R85.9 Unspecified abnormal finding	0.002	0.998	0.000
M91-M94 Chondropathies	0.002	0.998	0.000
T88.4 Failed or difficult intubation	0.000	0.998	0.002
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.998	0.002
T23.1 Burn of first degree of wrist and hand	0.001	0.998	0.000
M94.29 Chondromalacia (Site unspecified)	0.001	0.998	0.000
M94.28 Chondromalacia (Other)	0.001	0.998	0.000
M94.27 Chondromalacia (Ankle and foot)	0.001	0.998	0.000
M94.25 Chondromalacia (Pelvic region and thigh)	0.001	0.998	0.000
M94.24 Chondromalacia (Hand)	0.001	0.998	0.000
M94.23 Chondromalacia (Forearm)	0.001	0.998	0.000
M94.22 Chondromalacia (Upper arm)	0.001	0.998	0.000
M94.21 Chondromalacia (Shoulder region)	0.001	0.998	0.000
M94.20 Chondromalacia (Multiple sites)	0.001	0.998	0.000
R85.6 Abnormal cytological findings	0.001	0.998	0.000
R85.4 Abnormal immunological findings	0.001	0.998	0.000
R85.3 Abnormal level of substances chiefly nonmedicinal as to source	0.001	0.998	0.000
R85.2 Abnormal level of other drugs, medicaments and biological substances	0.001	0.998	0.000
R85.1 Abnormal level of hormones	0.001	0.998	0.000
R85.0 Abnormal level of enzymes	0.001	0.998	0.000
B02 Zoster [herpes zoster]	0.002	0.998	0.000
S12.71 Multiple fractures of cervical spine (open)	0.001	0.998	0.000
W51.5 Trade and service area	0.001	0.998	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.998	0.001
E00 Congenital iodine-deficiency syndrome	0.000	0.998	0.001
M94.08 Chondrocostal junction syndrome [Tietze]-Other	0.001	0.998	0.000
M94.07 Chondrocostal junction syndrome [Tietze]-Ankle/foot	0.001	0.998	0.000
M94.06 Chondrocostal junction syndrome [Tietze]-Lower leg	0.001	0.998	0.000
M94.05 Chondrocostal junction syndrome [Tietze]-Pelvic/thigh	0.001	0.998	0.000
M94.04 Chondrocostal junction syndrome [Tietze]-Hand	0.001	0.998	0.000
M94.03 Chondrocostal junction syndrome [Tietze]-Forearm	0.001	0.998	0.000
M94.02 Chondrocostal junction syndrome [Tietze]-Upper arm	0.001	0.998	0.000
M94.01 Chondrocostal junction syndrome [Tietze]-Shldr region	0.001	0.998	0.000
M94.00 Chondrocostal junction syndrome [Tietze]-Mult sites	0.001	0.998	0.000
B01.8 Varicella with other complications	0.001	0.998	0.000
Z11.2 Special screening examination for other bacterial diseases	0.000	0.998	0.002
S12 Fracture of neck	0.002	0.998	0.000
B00.4 Herpesviral encephalitis	0.001	0.998	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.002	0.998	0.000
M31.0 Hypersensitivity angiitis	0.001	0.998	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.998	0.002
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.000	0.998	0.001
Z58.1 Exposure to air pollution	0.001	0.998	0.000
M92 Other juvenile osteochondrosis	0.001	0.998	0.000
M91.15 Juv osteochondrosis head of femur [Legg-Calve-Perthes]-Pelv	0.001	0.998	0.000
M94.26 Chondromalacia (Lower leg)	0.001	0.998	0.000
W55.58 Bitten or struck by other mammals; Trade and service area;While engaged in other specified activities	0.001	0.998	0.000
W55.99 Bitten or struck by other mammals: Unspecified place: During unspecified activity	0.001	0.998	0.000
B00.9 Herpesviral infection, unspecified	0.001	0.998	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.002	0.998	0.000
Z80.3 Family history of malignant neoplasm of breast	0.000	0.998	0.002
M94.99 Disorder of cartilage, unspecified (Site unspecified)	0.001	0.998	0.000
M94.98 Disorder of cartilage, unspecified (Other)	0.001	0.998	0.000
M94.97 Disorder of cartilage, unspecified (Ankle and foot)	0.001	0.998	0.000
M94.95 Disorder of cartilage, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
M94.94 Disorder of cartilage, unspecified (Hand)	0.001	0.998	0.000
M94.93 Disorder of cartilage, unspecified (Forearm)	0.001	0.998	0.000
M94.92 Disorder of cartilage, unspecified (Upper arm)	0.001	0.998	0.000
M94.91 Disorder of cartilage, unspecified (Shoulder region)	0.001	0.998	0.000
M94.90 Disorder of cartilage, unspecified (Multiple sites)	0.001	0.998	0.000
M91.1 Juvenile osteochondrosis of head of femur [Legg-Calve-Perthes]	0.001	0.998	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.000	0.998	0.001
W51.9 Unspecified place	0.001	0.998	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.001	0.998	0.000
M93.26 Osteochondritis dissecans knee	0.001	0.999	0.000
M93.86 Other specified osteochondropathies, lower leg	0.001	0.999	0.000
M94.09 Chondrocostal junction syndrome [Tietze]-Site unspec	0.001	0.999	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.000	0.999	0.001
T88.1 Other complications following immunisation, not elsewhere classified	0.000	0.999	0.001
T88.0 Infection following immunisation	0.000	0.999	0.001
T25 Burn and corrosion of ankle and foot	0.001	0.999	0.000
W51 Striking against or bumped into by another person	0.001	0.999	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.001	0.999	0.000
S12.9 Fracture of neck, part unspecified	0.001	0.999	0.000
T21.0 Burn of unspecified degree of trunk	0.001	0.999	0.000
M31 Other necrotising vasculopathies	0.001	0.999	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.001	0.999	0.000
K04.8 Radicular cyst	0.001	0.999	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.001	0.999	0.000
S92.50 Fracture of other toe (closed)	0.001	0.999	0.000
B02.7 Disseminated zoster	0.001	0.999	0.000
B02.1 Zoster meningitis	0.001	0.999	0.000
B02.0 Zoster encephalitis	0.001	0.999	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.001	0.999	0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess	0.000	0.999	0.001
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.999	0.001
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.999	0.001
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.999	0.001
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.999	0.001
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.999	0.001
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.999	0.001
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.999	0.001
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.999	0.001
M92.6 Juvenile osteochondrosis of tarsus	0.001	0.999	0.000
M94.96 Disorder of cartilage, unspecified (Lower leg)	0.001	0.999	0.001
S12.8 Fracture of other parts of neck	0.001	0.999	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.001	0.999	0.000
Z43.6 Attention to other artificial openings of urinary tract	0.000	0.999	0.001
B01 Varicella [chickenpox]	0.001	0.999	0.000
T21 Burn and corrosion of trunk	0.001	0.999	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
B01.2 Varicella pneumonia	0.001	0.999	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
X47.0 Home	0.001	0.999	0.000
M77.02 Medial epicondylitis (Upper arm)	0.001	0.999	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.001	0.999	0.000
H61.0 Perichondritis of external ear	0.001	0.999	0.000
M92.5 Juvenile osteochondrosis of tibia and fibula	0.001	0.999	0.000
M92.1 Juvenile osteochondrosis of radius and ulna	0.001	0.999	0.000
M92.9 Juvenile osteochondrosis, unspecified	0.001	0.999	0.000
M92.8 Other specified juvenile osteochondrosis	0.001	0.999	0.000
M92.4 Juvenile osteochondrosis of patella	0.001	0.999	0.000
M92.3 Other juvenile osteochondrosis of upper limb	0.001	0.999	0.000
M92.2 Juvenile osteochondrosis of hand	0.001	0.999	0.000
M92.0 Juvenile osteochondrosis of humerus	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations