TreeWAS – Variant ID: rs10224002

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N20 Calculus of kidney and ureter	0.000	0.005	0.995
N20.0 Calculus of kidney	0.000	0.008	0.992
N20.1 Calculus of ureter	0.000	0.015	0.985
N20-N23 Urolithiasis	0.000	0.015	0.985
N21 Calculus of lower urinary tract	0.000	0.015	0.985
N21.0 Calculus in bladder	0.000	0.016	0.984
I10 Essential (primary) hypertension	0.953	0.047	0.000
N20.2 Calculus of kidney with calculus of ureter	0.000	0.076	0.924
N21.1 Calculus in urethra	0.000	0.188	0.812
N20.9 Urinary calculus, unspecified	0.000	0.203	0.797
N21.8 Other lower urinary tract calculus	0.000	0.245	0.755
N22 Calculus of urinary tract in diseases classified elsewhere	0.000	0.294	0.706
N21.9 Calculus of lower urinary tract, unspecified	0.000	0.294	0.706
N22.8 Calculus of urinary tract in other diseases classified elsewhere	0.000	0.493	0.506
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]	0.000	0.493	0.506
N23 Unspecified renal colic	0.000	0.595	0.405
I10-I15 Hypertensive diseases	0.241	0.759	0.000
I13 Hypertensive heart and renal disease	0.173	0.827	0.000
I11 Hypertensive heart disease	0.168	0.832	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.141	0.859	0.000
I12 Hypertensive renal disease	0.136	0.864	0.000
I15 Secondary hypertension	0.128	0.872	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.124	0.876	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.124	0.876	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.124	0.876	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.124	0.876	0.000
I15.8 Other secondary hypertension	0.102	0.897	0.000
I08.0 Disorders of both mitral and aortic valves	0.102	0.898	0.000
I08 Multiple valve diseases	0.100	0.900	0.000
I12.9 Hypertensive renal disease without renal failure	0.095	0.904	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.095	0.905	0.000
I15.2 Hypertension secondary to endocrine disorders	0.092	0.908	0.000
I15.0 Renovascular hypertension	0.092	0.908	0.000
I08.8 Other multiple valve diseases	0.087	0.913	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.086	0.914	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.075	0.924	0.000
I08.9 Multiple valve disease, unspecified	0.073	0.927	0.000
I15.9 Seconday hypertension, unspecified	0.069	0.931	0.001
I12.0 Hypertensive renal disease with renal failure	0.066	0.934	0.000
I05-I09 Chronic rheumatic heart diseases	0.062	0.938	0.000
I15.1 Hypertension secondary to other renal disorders	0.057	0.943	0.001
Chapter IX Diseases of the circulatory system	0.055	0.945	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.053	0.947	0.000
I69 Sequelae of cerebrovascular disease	0.051	0.949	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.049	0.951	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.047	0.953	0.000
I60-I69 Cerebrovascular diseases	0.047	0.953	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.046	0.954	0.000
I69.3 Sequelae of cerebral infarction	0.044	0.956	0.000
U80.1 Methicillin resistant agent	0.000	0.956	0.044
U80 Agent resistant to penicillin and related antibiotics	0.000	0.957	0.043
I06 Rheumatic aortic valve diseases	0.043	0.957	0.000
I00-I02 Acute rheumatic fever	0.041	0.959	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.959	0.041
I61 Intracerebral haemorrhage	0.041	0.959	0.000
I09 Other rheumatic heart diseases	0.040	0.960	0.000
I07 Rheumatic tricuspid valve diseases	0.040	0.960	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.000	0.963	0.037
I61.8 Other intracerebral haemorrhage	0.036	0.964	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.035	0.965	0.000
U51 Admission status on psychiatric patients	0.000	0.966	0.034
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.034	0.966	0.000
I95.1 Orthostatic hypotension	0.034	0.966	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.034	0.966	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.034	0.966	0.000
U80.0 Penicillin resistant agent	0.000	0.967	0.033
I62 Other nontraumatic intracranial haemorrhage	0.033	0.967	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.032	0.967	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.032	0.968	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.032	0.968	0.000
U81 Agent resistant to vancomycin and related antibiotics	0.000	0.968	0.032
I61.4 Intracerebral haemorrhage in cerebellum	0.032	0.968	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.032	0.968	0.000
I95 Hypotension	0.031	0.969	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.031	0.969	0.000
I06.8 Other rheumatic aortic valve diseases	0.031	0.969	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.031	0.969	0.000
I06.1 Rheumatic aortic insufficiency	0.031	0.969	0.000
U51.1 Previously admitted to a psychiatric hospital of the provider	0.000	0.969	0.031
I00 Rheumatic fever without mention of heart involvement	0.031	0.969	0.000
I67 Other cerebrovascular diseases	0.031	0.969	0.000
I06.0 Rheumatic aortic stenosis	0.030	0.970	0.000
I02 Rheumatic chorea	0.029	0.970	0.000
I01 Rheumatic fever with heart involvement	0.029	0.970	0.000
I09.8 Other specified rheumatic heart diseases	0.029	0.971	0.000
I09.2 Chronic rheumatic pericarditis	0.029	0.971	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.029	0.971	0.000
I09.0 Rheumatic myocarditis	0.029	0.971	0.000
I07.9 Tricuspid valve disease, unspecified	0.029	0.971	0.000
I07.8 Other tricuspid valve diseases	0.029	0.971	0.000
I07.2 Tricuspid stenosis with insufficiency	0.029	0.971	0.000
I07.0 Tricuspid stenosis	0.029	0.971	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.028	0.972	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.028	0.972	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.028	0.972	0.000
U81.0 Vancomycin resistant agent	0.000	0.972	0.028
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.028	0.972	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.028	0.972	0.000
U51.0 Not Previously admitted to a psyciatric hospital	0.000	0.972	0.028
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.027	0.972	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.027	0.973	0.000
U50 Level of care administered to neonates	0.000	0.973	0.027
U07 Emergency use of U07	0.000	0.973	0.027
U06 Emergency use of U06	0.000	0.973	0.027
U04 Severe acute respiratory syndrome [SARS]	0.000	0.973	0.027
U52 First in a series of a regular day/night admissions	0.000	0.973	0.027
I67.8 Other specified cerebrovascular diseases	0.027	0.973	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.026	0.973	0.000
I05 Rheumatic mitral valve diseases	0.026	0.974	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.026	0.974	0.000
I09.9 Rheumatic heart disease, unspecified	0.025	0.975	0.000
U51.2 Previously admitted to a psychiatric hospital of another provider	0.000	0.975	0.025
I07.1 Tricuspid insufficiency	0.025	0.975	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.024	0.975	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.024	0.975	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.024	0.975	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.024	0.975	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.024	0.975	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.024	0.976	0.000
I65.1 Occlusion and stenosis of basilar artery	0.024	0.976	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.023	0.977	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.023	0.977	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.023	0.977	0.000
U81.8 Agent resistant to other vancomycin-related antibiotic	0.000	0.977	0.023
I67.2 Cerebral atherosclerosis	0.023	0.977	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.023	0.977	0.000
I95.0 Idiopathic hypotension	0.023	0.977	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.023	0.977	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.022	0.978	0.000
I67.5 Moyamoya disease	0.022	0.978	0.000
I67.4 Hypertensive encephalopathy	0.022	0.978	0.000
I67.3 Progressive vascular leukoencephalopathy	0.022	0.978	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.022	0.978	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.022	0.978	0.000
I68.0 Cerebral amyloid angiopathy	0.022	0.978	0.000
I62.1 Nontraumatic extradural haemorrhage	0.022	0.978	0.000
I95.8 Other hypotension	0.022	0.978	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.021	0.979	0.000
I01.8 Other acute rheumatic heart disease	0.021	0.979	0.000
I01.2 Acute rheumatic myocarditis	0.021	0.979	0.000
I01.1 Acute rheumatic endocarditis	0.021	0.979	0.000
I01.0 Acute rheumatic pericarditis	0.021	0.979	0.000
I02.9 Rheumatic chorea without heart involvement	0.021	0.979	0.000
I02.0 Rheumatic chorea with heart involvement	0.021	0.979	0.000
I65.2 Occlusion and stenosis of carotid artery	0.021	0.979	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.021	0.979	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.020	0.979	0.000
I67.9 Cerebrovascular disease, unspecified	0.021	0.979	0.000
I28 Other diseases of pulmonary vessels	0.020	0.979	0.000
I95.2 Hypotension due to drugs	0.020	0.980	0.000
U04.9 Severe acute respiratory syndrome [SARS], unspecified	0.000	0.980	0.019
U06.9 Emergency use of U06.9	0.000	0.980	0.019
U06.8 Emergency use of U06.8	0.000	0.980	0.019
U06.7 Emergency use of U06.7	0.000	0.980	0.019
U06.6 Emergency use of U06.6	0.000	0.980	0.019
U06.5 Emergency use of U06.5	0.000	0.980	0.019
U06.4 Emergency use of U06.4	0.000	0.980	0.019
U06.3 Emergency use of U06.3	0.000	0.980	0.019
U06.2 Emergency use of U06.2	0.000	0.980	0.019
U06.1 Emergency use of U06.1	0.000	0.980	0.019
U06.0 Emergency use of U06.0	0.000	0.980	0.019
U07.9 Emergency use of U07.9	0.000	0.980	0.019
U07.8 Emergency use of U07.8	0.000	0.980	0.019
U07.7 Emergency use of U07.7	0.000	0.980	0.019
U07.6 Emergency use of U07.6	0.000	0.980	0.019
U07.5 Emergency use of U07.5	0.000	0.980	0.019
U07.4 Emergency use of U07.4	0.000	0.980	0.019
U07.3 Emergency use of U07.3	0.000	0.980	0.019
U07.2 Emergency use of U07.2	0.000	0.980	0.019
U07.1 Emergency use of U07.1	0.000	0.980	0.019
U07.0 Emergency use of U07.0	0.000	0.980	0.019
U50.9 Inquest Adjourned Death	0.000	0.980	0.019
U50.3 Level of care administered to neonates (Maximal Intensive Care)	0.000	0.980	0.019
U50.2 Level of care administered to neonates (High Dependancy Intensive Care)	0.000	0.980	0.019
U50.1 Level of care administered to neonates (Special Care)	0.000	0.980	0.019
U50.0 Level of care administered to neonates (Normal Care)	0.000	0.980	0.019
R55 Syncope and collapse	0.019	0.981	0.000
I05.8 Other mitral valve diseases	0.019	0.981	0.000
I05.2 Mitral stenosis with insufficiency	0.019	0.981	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.018	0.982	0.000
I27 Other pulmonary heart diseases	0.018	0.982	0.000
I99 Other and unspecified disorders of circulatory system	0.018	0.982	0.000
I05.1 Rheumatic mitral insufficiency	0.017	0.982	0.000
I97.0 Postcardiotomy syndrome	0.017	0.983	0.000
I97.1 Other functional disturbances following cardiac surgery	0.017	0.983	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.017	0.983	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.017	0.983	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.017	0.983	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.016	0.984	0.000
I05.9 Mitral valve disease, unspecified	0.016	0.984	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.015	0.985	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.015	0.985	0.000
I28.1 Aneurysm of pulmonary artery	0.015	0.985	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.015	0.985	0.000
I28.8 Other specified diseases of pulmonary vessels	0.015	0.985	0.000
I27.0 Primary pulmonary hypertension	0.015	0.985	0.000
I24 Other acute ischaemic heart diseases	0.014	0.986	0.000
I20-I25 Ischaemic heart diseases	0.014	0.986	0.000
I26 Pulmonary embolism	0.014	0.986	0.000
I27.8 Other specified pulmonary heart diseases	0.014	0.986	0.000
I27.1 Kyphoscoliotic heart disease	0.013	0.987	0.000
I27.2 Other secondary pulmonary hypertension	0.013	0.987	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.013	0.987	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.987	0.013
G60.0 Hereditary motor and sensory neuropathy	0.000	0.987	0.013
I05.0 Mitral stenosis	0.012	0.988	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.012	0.988	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.012	0.988	0.000
I98.0 Cardiovascular syphilis	0.012	0.988	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.012	0.988	0.000
L08.8 Other specified local infections of skin and subcutaneous tissue	0.000	0.988	0.012
I67.1 Cerebral aneurysm, nonruptured	0.012	0.988	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.000	0.988	0.012
I60 Subarachnoid haemorrhage	0.011	0.989	0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.000	0.989	0.011
I24.1 Dressler's syndrome	0.011	0.989	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.011	0.989	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.011	0.989	0.000
Chapter XXII Codes for special purposes	0.000	0.989	0.011
L08 Other local infections of skin and subcutaneous tissue	0.000	0.990	0.010
I23 Certain current complications following acute myocardial infarction	0.010	0.990	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.000	0.990	0.010
G60 Hereditary and idiopathic neuropathy	0.000	0.990	0.010
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.000	0.990	0.010
L92.0 Granuloma annulare	0.000	0.991	0.009
I60.4 Subarachnoid haemorrhage from basilar artery	0.009	0.991	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.009	0.991	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.009	0.991	0.000
I21 Acute myocardial infarction	0.009	0.991	0.000
I27.9 Pulmonary heart disease, unspecified	0.009	0.991	0.000
D86.9 Sarcoidosis, unspecified	0.009	0.991	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.008	0.992	0.000
G63.2 Diabetic polyneuropathy	0.000	0.992	0.008
I60.5 Subarachnoid haemorrhage from vertebral artery	0.008	0.992	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.008	0.992	0.000
N28.8 Other specified disorders of kidney and ureter	0.000	0.992	0.008
G63 Polyneuropathy in diseases classified elsewhere	0.000	0.992	0.008
L08.1 Erythrasma	0.000	0.992	0.007
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.000	0.992	0.008
I60.8 Other subarachnoid haemorrhage	0.007	0.992	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.000	0.992	0.008
I21.9 Acute myocardial infarction, unspecified	0.008	0.992	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.007	0.993	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.007	0.993	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.007	0.993	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.007	0.993	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.007	0.993	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.007	0.993	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.007	0.993	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.007	0.993	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.007	0.993	0.000
L92.1 Necrobiosis lipoidica, not elsewhere classified	0.000	0.993	0.007
D86.8 Sarcoidosis of other and combined sites	0.007	0.993	0.000
I23.8 Other current complications following acute myocardial infarction	0.007	0.993	0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.000	0.993	0.007
G60.3 Idiopathic progressive neuropathy	0.000	0.993	0.007
G60.2 Neuropathy in association with hereditary ataxia	0.000	0.993	0.007
G60.1 Refsum's disease	0.000	0.993	0.007
G60.8 Other hereditary and idiopathic neuropathies	0.000	0.993	0.007
L08.0 Pyoderma	0.000	0.993	0.007
D86 Sarcoidosis	0.007	0.993	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.007	0.993	0.000
L92.2 Granuloma faciale [eosinophilic granuloma of skin]	0.000	0.993	0.007
I98.2 Oesophageal varices in diseases classified elsewhere	0.007	0.993	0.000
I70 Atherosclerosis	0.007	0.993	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.007	0.993	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.006	0.993	0.000
G62 Other polyneuropathies	0.000	0.994	0.006
I70.2 Atherosclerosis of arteries of the extremities	0.006	0.994	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.000	0.994	0.006
G63.6 Polyneuropathy in other musculoskeletal disorders	0.000	0.994	0.006
G63.5 Polyneuropathy in systemic connective tissue disorders	0.000	0.994	0.006
G63.4 Polyneuropathy in nutritional deficiency	0.000	0.994	0.006
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.000	0.994	0.006
G63.1 Polyneuropathy in neoplastic disease	0.000	0.994	0.006
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.000	0.994	0.006
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.000	0.994	0.006
I21.1 Acute transmural myocardial infarction of inferior wall	0.006	0.994	0.000
G62.8 Other specified polyneuropathies	0.000	0.994	0.006
I21.3 Acute transmural myocardial infarction of unspecified site	0.006	0.994	0.000
G64 Other disorders of peripheral nervous system	0.000	0.994	0.006
G62.0 Drug-induced polyneuropathy	0.000	0.994	0.006
I70.1 Atherosclerosis of renal artery	0.005	0.994	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.006	0.994	0.000
I78 Diseases of capillaries	0.006	0.994	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.005	0.994	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.000	0.994	0.005
D86.3 Sarcoidosis of skin	0.005	0.995	0.000
D86.1 Sarcoidosis of lymph nodes	0.005	0.995	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.005	0.995	0.000
I70.0 Atherosclerosis of aorta	0.005	0.995	0.000
G61 Inflammatory polyneuropathy	0.000	0.995	0.005
I71 Aortic aneurysm and dissection	0.005	0.995	0.000
I70.9 Generalised and unspecified atherosclerosis	0.005	0.995	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.005	0.995	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.005	0.995	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.005	0.995	0.000
I24.8 Other forms of acute ischaemic heart disease	0.005	0.995	0.000
G62.2 Polyneuropathy due to other toxic agents	0.000	0.995	0.005
I70.8 Atherosclerosis of other arteries	0.004	0.995	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.005	0.995	0.000
I78.8 Other diseases of capillaries	0.005	0.995	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.004	0.996	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.004	0.996	0.000
I78.9 Disease of capillaries, unspecified	0.004	0.996	0.000
U84 Resistance to other antimicrobial drugs	0.000	0.996	0.004
U83 Resistance to other antibiotics	0.000	0.996	0.004
U82 Resistance to betalactam antibiotics	0.000	0.996	0.004
U85 Resistance to antineoplastic drugs	0.000	0.996	0.004
I71.3 Abdominal aortic aneurysm, ruptured	0.004	0.996	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.004	0.996	0.000
I63 Cerebral infarction	0.004	0.996	0.000
G62.1 Alcoholic polyneuropathy	0.000	0.996	0.004
I70.01 Atherosclerosis of aorta (with gangrene)	0.004	0.996	0.000
G61.1 Serum neuropathy	0.000	0.996	0.004
I71.8 Aortic aneurysm of unspecified site, ruptured	0.004	0.996	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.004	0.996	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.004	0.996	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.004	0.996	0.000
G61.8 Other inflammatory polyneuropathies	0.000	0.996	0.004
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.004	0.996	0.000
I79.1 Aortitis in diseases classified elsewhere	0.004	0.996	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.004	0.996	0.000
I73 Other peripheral vascular diseases	0.004	0.996	0.000
D86.0 Sarcoidosis of lung	0.004	0.996	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.004	0.996	0.000
G61.0 Guillain-Barre syndrome	0.000	0.996	0.004
I71.1 Thoracic aortic aneurysm, ruptured	0.004	0.996	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.000	0.996	0.004
I70.81 Atherosclerosis of other arteries (with gangrene)	0.003	0.996	0.000
I72 Other aneurysm	0.004	0.996	0.000
U89 Agent resistant to other and unspecified antibiotics	0.000	0.996	0.003
I73.8 Other specified peripheral vascular diseases	0.003	0.996	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.003	0.997	0.000
J69.0 Pneumonitis due to food and vomit	0.000	0.997	0.003
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.003	0.997	0.000
U82.9 Resistance to betalactam antibiotics, unspecified	0.000	0.997	0.003
U82.8 Resistance to other betalactam antibiotics	0.000	0.997	0.003
U82.2 Extended spectrum betalactamase (ESBL) resistance	0.000	0.997	0.003
U82.1 Resistance to methicillin	0.000	0.997	0.003
U82.0 Resistance to penicillin	0.000	0.997	0.003
U83.9 Resistance to unspecified antibiotic	0.000	0.997	0.003
U83.8 Resistance to other single specified antibiotic	0.000	0.997	0.003
U83.7 Resistance to multiple antibiotics	0.000	0.997	0.003
U83.2 Resistance to quinolones	0.000	0.997	0.003
U83.1 Resistance to other vancomycin related antibiotics	0.000	0.997	0.003
U83.0 Resistance to vancomycin	0.000	0.997	0.003
U84.9 Resistance to unspecified antimicrobial drugs	0.000	0.997	0.003
U84.8 Resistance to other specified antimicrobial drug	0.000	0.997	0.003
U84.7 Resistance to multiple antimicrobial drugs	0.000	0.997	0.003
U84.3 Resistance to tuberculostatic drug(s)	0.000	0.997	0.003
U84.2 Resistance to antiviral drug(s)	0.000	0.997	0.003
U84.1 Resistance to antifungal drug(s)	0.000	0.997	0.003
U84.0 Resistance to antiparasitic drug(s)	0.000	0.997	0.003
C43.6 Malignant melanoma of upper limb, including shoulder	0.003	0.997	0.000
T78.2 Anaphylactic shock, unspecified	0.000	0.997	0.003
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.003	0.997	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.003	0.997	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.003	0.997	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.003	0.997	0.000
I72.3 Aneurysm of iliac artery	0.003	0.997	0.000
K38.0 Hyperplasia of appendix	0.003	0.997	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.003	0.997	0.000
I22 Subsequent myocardial infarction	0.003	0.997	0.000
K38 Other diseases of appendix	0.003	0.997	0.000
K38.8 Other specified diseases of appendix	0.003	0.997	0.000
E55.9 Vitamin D deficiency, unspecified	0.000	0.997	0.003
I73.1 Thromboangiitis obliterans [Buerger]	0.003	0.997	0.000
K38.1 Appendicular concretions	0.003	0.997	0.000
S92.30 Fracture of metatarsal bone (closed)	0.003	0.997	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.997	0.003
K58.0 Irritable bowel syndrome with diarrhoea	0.000	0.997	0.003
I72.9 Aneurysm of unspecified site	0.003	0.997	0.000
I71.0 Dissection of aorta [any part]	0.003	0.997	0.000
I72.1 Aneurysm of artery of upper extremity	0.003	0.997	0.000
Q82.8 Other specified congenital malformations of skin	0.003	0.997	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.003	0.997	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.003	0.997	0.000
U89.9 Agent resistant to unspecified antibiotic	0.000	0.997	0.003
K86.1 Other chronic pancreatitis	0.000	0.997	0.003
U88 Agent resistant to multiple antibiotics	0.000	0.997	0.003
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.997	0.003
I21.4 Acute subendocardial myocardial infarction	0.003	0.997	0.000
I72.2 Aneurysm of renal artery	0.003	0.997	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.000	0.997	0.003
F80.1 Expressive language disorder	0.003	0.997	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.003	0.997	0.000
K38.9 Disease of appendix, unspecified	0.003	0.997	0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.000	0.997	0.003
K38.3 Fistula of appendix	0.002	0.997	0.000
K38.2 Diverticulum of appendix	0.002	0.997	0.000
N03.9 Unspecified	0.003	0.997	0.000
I74 Arterial embolism and thrombosis	0.003	0.997	0.000
T40.2 Other opioids	0.000	0.997	0.003
I60.9 Subarachnoid haemorrhage, unspecified	0.002	0.998	0.000
I78.1 Naevus, nonneoplastic	0.002	0.998	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.002	0.998	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.000	0.998	0.002
I74.8 Embolism and thrombosis of other arteries	0.002	0.998	0.000
J69.8 Pneumonitis due to other solids and liquids	0.000	0.998	0.002
L43.9 Lichen planus, unspecified	0.002	0.998	0.000
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
I72.0 Aneurysm of carotid artery	0.002	0.998	0.000
C43.5 Malignant melanoma of trunk	0.002	0.998	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.002	0.998	0.000
I63.8 Other cerebral infarction	0.002	0.998	0.000
K60.3 Anal fistula	0.000	0.998	0.002
J69 Pneumonitis due to solids and liquids	0.000	0.998	0.002
I72.4 Aneurysm of artery of lower extremity	0.002	0.998	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.002	0.998	0.000
I73.0 Raynaud's syndrome	0.002	0.998	0.000
Z22.3 Carrier of other specified bacterial diseases	0.000	0.998	0.002
I74.9 Embolism and thrombosis of unspecified artery	0.002	0.998	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
K35.3 Acute appendicitis with localized peritonitis	0.002	0.998	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.998	0.002
G62.9 Polyneuropathy, unspecified	0.000	0.998	0.002
H72.0 Central perforation of tympanic membrane	0.000	0.998	0.002
I22.9 Subsequent myocardial infarction of unspecified site	0.002	0.998	0.000
K86.3 Pseudocyst of pancreas	0.000	0.998	0.002
D58.9 Hereditary haemolytic anaemia, unspecified	0.002	0.998	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.002	0.998	0.000
S06.4 Epidural haemorrhage	0.002	0.998	0.000
U89.8 Agent resistant to other single specified antibiotic	0.000	0.998	0.002
L85.8 Other specified epidermal thickening	0.002	0.998	0.000
K86 Other diseases of pancreas	0.000	0.998	0.002
I85.9 Oesophageal varices without bleeding	0.000	0.998	0.002
X23.9 Unspecified place	0.000	0.998	0.002
K86.2 Cyst of pancreas	0.000	0.998	0.002
E55 Vitamin D deficiency	0.000	0.998	0.002
Z40.8 Other prophylactic surgery	0.002	0.998	0.000
D83 Common variable immunodeficiency	0.002	0.998	0.000
I22.8 Subsequent myocardial infarction of other sites	0.002	0.998	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.002	0.998	0.000
S32.50 Fracture of pubis (closed)	0.002	0.998	0.000
N83.0 Follicular cyst of ovary	0.002	0.998	0.000
D82 Immunodeficiency associated with other major defects	0.002	0.998	0.000
D81 Combined immunodeficiencies	0.002	0.998	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.998	0.002
K35.8 Acute appendicitis, other and unspecified	0.002	0.998	0.000
M25.78 Osteophyte (Other)	0.000	0.998	0.002
I22.0 Subsequent myocardial infarction of anterior wall	0.002	0.998	0.000
F80 Specific developmental disorders of speech and language	0.002	0.998	0.000
F80.2 Receptive language disorder	0.002	0.998	0.000
I72.8 Aneurysm of other specified arteries	0.002	0.998	0.000
I74.5 Embolism and thrombosis of iliac artery	0.002	0.998	0.000
J69.1 Pneumonitis due to oils and essences	0.000	0.998	0.002
D84 Other immunodeficiencies	0.002	0.998	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.998	0.002
S92.3 Fracture of metatarsal bone	0.002	0.998	0.000
Z96.2 Presence of otological and audiological implants	0.000	0.998	0.002
D26.1 Corpus uteri	0.000	0.998	0.002
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.002	0.998	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.002	0.998	0.000
H72.8 Other perforations of tympanic membrane	0.000	0.998	0.002
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
T78.3 Angioneurotic oedema	0.000	0.998	0.002
H72 Perforation of tympanic membrane	0.000	0.998	0.002
J80 Adult respiratory distress syndrome	0.002	0.998	0.000
K86.9 Disease of pancreas, unspecified	0.000	0.998	0.002
S06.41 Epidural haemorrhage (with open intracranial wound)	0.002	0.998	0.000
D84.8 Other specified immunodeficiencies	0.002	0.998	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.001	0.998	0.000
K61.1 Rectal abscess	0.000	0.998	0.002
K91.4 Colostomy and enterostomy malfunction	0.000	0.998	0.002
Z35.5 Supervision of elderly primigravida	0.002	0.998	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.002	0.998	0.000
M31.6 Other giant cell arteritis	0.002	0.998	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.002	0.998	0.000
D83.9 Common variable immunodeficiency, unspecified	0.001	0.998	0.000
C43 Malignant melanoma of skin	0.002	0.998	0.000
D58 Other hereditary haemolytic anaemias	0.002	0.998	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.001	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.001	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.001	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.001	0.998	0.000
E55.0 Rickets, active	0.000	0.998	0.001
H72.1 Attic perforation of tympanic membrane	0.000	0.998	0.002
S71.1 Open wound of thigh	0.002	0.998	0.000
C43.9 Malignant melanoma of skin, unspecified	0.002	0.998	0.000
D81.9 Combined immunodeficiency, unspecified	0.001	0.998	0.000
D81.8 Other combined immunodeficiencies	0.001	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.001	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.001	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.001	0.998	0.000
D81.4 Nezelof's syndrome	0.001	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.001	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.001	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.001	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.001	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.001	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.001	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.001	0.998	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.001	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.001	0.998	0.000
D82.1 Di George's syndrome	0.001	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.001	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
F80.9 Developmental disorder of speech and language, unspecified	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations