TreeWAS – Variant ID: rs1022515

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.600	0.400
E10.9 Without complications	0.000	0.603	0.397
E10.4 With neurological complications	0.000	0.629	0.371
E10.5 With peripheral circulatory complications	0.000	0.638	0.362
E10.6 With other specified complications	0.000	0.639	0.361
E10.8 With unspecified complications	0.000	0.663	0.337
K90 Intestinal malabsorption	0.000	0.687	0.313
E10-E14 Diabetes mellitus	0.000	0.692	0.308
E10.1 With ketoacidosis	0.000	0.700	0.299
E10.2 With renal complications	0.000	0.701	0.298
E83 Disorders of mineral metabolism	0.000	0.710	0.290
E10.7 With multiple complications	0.000	0.713	0.287
E10.0 With coma	0.000	0.729	0.271
E13 Other specified diabetes mellitus	0.000	0.739	0.261
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.742	0.258
E10.3 With ophthalmic complications	0.000	0.743	0.257
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.759	0.241
E70-E90 Metabolic disorders	0.000	0.759	0.241
E14 Unspecified diabetes mellitus	0.000	0.767	0.233
E13.9 Without complications	0.000	0.771	0.229
K90.3 Pancreatic steatorrhoea	0.000	0.775	0.224
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.775	0.224
K90.1 Tropical sprue	0.000	0.775	0.224
E14.3 With ophthalmic complications	0.000	0.777	0.223
E12 Malnutrition-related diabetes mellitus	0.000	0.779	0.221
K90.8 Other intestinal malabsorption	0.000	0.784	0.216
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.791	0.209
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.792	0.208
E83.8 Other disorders of mineral metabolism	0.000	0.792	0.208
E83.2 Disorders of zinc metabolism	0.000	0.792	0.208
E83.0 Disorders of copper metabolism	0.000	0.792	0.208
E88 Other metabolic disorders	0.000	0.797	0.203
E40-E46 Malnutrition	0.000	0.798	0.202
E85 Amyloidosis	0.000	0.805	0.195
E13.8 With unspecified complications	0.000	0.813	0.187
E13.7 With multiple complications	0.000	0.813	0.187
E13.6 With other specified complications	0.000	0.813	0.187
E13.5 With peripheral circulatory complications	0.000	0.813	0.187
E13.4 With neurological complications	0.000	0.813	0.187
E13.2 With renal complications	0.000	0.813	0.187
E13.1 With ketoacidosis	0.000	0.813	0.187
E13.0 With coma	0.000	0.813	0.187
E16 Other disorders of pancreatic internal secretion	0.000	0.814	0.186
E13.3 With ophthalmic complications	0.000	0.817	0.183
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.824	0.176
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.824	0.176
E16.2 Hypoglycaemia, unspecified	0.000	0.825	0.175
E46 Unspecified protein-energy malnutrition	0.000	0.826	0.174
E14.5 With peripheral circulatory complications	0.000	0.826	0.174
E84 Cystic fibrosis	0.000	0.827	0.173
E77 Disorders of glycoprotein metabolism	0.000	0.827	0.173
E76 Disorders of glycosaminoglycan metabolism	0.000	0.827	0.173
E72 Other disorders of amino-acid metabolism	0.000	0.827	0.173
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.827	0.173
E70 Disorders of aromatic amino-acid metabolism	0.000	0.827	0.173
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.827	0.173
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.829	0.171
E14.7 With multiple complications	0.000	0.833	0.167
E14.6 With other specified complications	0.000	0.833	0.167
E14.2 Withrenal complications	0.000	0.833	0.167
E14.0 With coma	0.000	0.833	0.167
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.835	0.165
E85.9 Amyloidosis, unspecified	0.000	0.837	0.163
E14.4 With neurological complications	0.000	0.839	0.161
E65-E68 Obesity and other hyperalimentation	0.000	0.841	0.159
E12.9 Without complications	0.000	0.841	0.158
E12.8 With unspecified complications	0.000	0.841	0.158
E12.7 With multiple complications	0.000	0.841	0.158
E12.6 With other specified complications	0.000	0.841	0.158
E12.5 With peripheral circulatory complications	0.000	0.841	0.158
E12.4 With neurological complications	0.000	0.841	0.158
E12.3 With ophthalmic complications	0.000	0.841	0.158
E12.2 With renal complications	0.000	0.841	0.158
E12.1 With ketoacidosis	0.000	0.841	0.158
E12.0 With coma	0.000	0.841	0.158
E79 Disorders of purine and pyrimidine metabolism	0.000	0.844	0.156
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.845	0.155
E88.8 Other specified metabolic disorders	0.000	0.846	0.154
E88.2 Lipomatosis, not elsewhere classified	0.000	0.847	0.153
E15 Nondiabetic hypoglycaemic coma	0.000	0.850	0.150
E85.4 Organ-limited amyloidosis	0.000	0.853	0.147
E88.3 Tumour lysis syndrome	0.000	0.854	0.146
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.855	0.145
E45 Retarded development following protein-energy malnutrition	0.000	0.855	0.145
E43 Unspecified severe protein-energy malnutrition	0.000	0.855	0.145
E42 Marasmic kwashiorkor	0.000	0.855	0.145
E41 Nutritional marasmus	0.000	0.855	0.145
E40 Kwashiorkor	0.000	0.855	0.145
E14.1 With ketoacidosis	0.000	0.858	0.142
E85.8 Other amyloidosis	0.000	0.860	0.140
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.860	0.140
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.860	0.140
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.860	0.140
E74 Other disorders of carbohydrate metabolism	0.000	0.861	0.138
E14.8 With unspecified complications	0.000	0.862	0.138
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.862	0.138
E89.2 Postprocedural hypoparathyroidism	0.000	0.864	0.136
E88.9 Metabolic disorder, unspecified	0.000	0.864	0.135
E65 Localised adiposity	0.000	0.866	0.134
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.866	0.133
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.866	0.133
E16.4 Abnormal secretion of gastrin	0.000	0.866	0.133
E16.3 Increased secretion of glucagon	0.000	0.866	0.133
E80.4 Gilbert's syndrome	0.000	0.867	0.133
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.868	0.132
E85.3 Secondary systemic amyloidosis	0.000	0.870	0.130
E75.5 Other lipid storage disorders	0.000	0.870	0.130
E80.2 Other porphyria	0.000	0.870	0.130
E73 Lactose intolerance	0.000	0.873	0.126
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.873	0.127
E80.5 Crigler-Najjar syndrome	0.000	0.873	0.127
E80.3 Defects of catalase and peroxydase	0.000	0.873	0.127
E80.1 Porphyria cutanea tarda	0.000	0.873	0.127
E80.0 Hereditary erythropoietic porphyria	0.000	0.873	0.127
E89.0 Postprocedural hypothyroidism	0.000	0.873	0.127
E75.6 Lipid storage disorder, unspecified	0.000	0.873	0.126
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.873	0.126
E75.3 Sphingolipidosis, unspecified	0.000	0.873	0.126
E75.2 Other sphingolipidosis	0.000	0.873	0.126
E75.1 Other gangliosidosis	0.000	0.873	0.126
E75.0 GM2 gangliosidosis	0.000	0.873	0.126
E83.3 Disorders of phosphorus metabolism	0.000	0.875	0.125
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.876	0.124
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.876	0.124
E70.3 Albinism	0.000	0.876	0.124
E70.2 Disorders of tyrosine metabolism	0.000	0.876	0.124
E70.1 Other hyperphenylalaninaemias	0.000	0.876	0.124
E70.0 Classical phenylketonuria	0.000	0.876	0.124
E71.3 Disorders of fatty-acid metabolism	0.000	0.876	0.124
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.876	0.124
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.876	0.124
E71.0 Maple-syrup-urine disease	0.000	0.876	0.124
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.876	0.124
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.876	0.124
E72.5 Disorders of glycine metabolism	0.000	0.876	0.124
E72.4 Disorders of ornithine metabolism	0.000	0.876	0.124
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.876	0.124
E72.2 Disorders of urea cycle metabolism	0.000	0.876	0.124
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.876	0.124
E72.0 Disorders of amino-acid transport	0.000	0.876	0.124
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.876	0.124
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.876	0.124
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.876	0.124
E76.2 Other mucopolysaccharidoses	0.000	0.876	0.124
E76.1 Mucopolysaccharidosis, type II	0.000	0.876	0.124
E76.0 Mucopolysaccharidosis, type I	0.000	0.876	0.124
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.876	0.124
E77.8 Other disorders of glycoprotein metabolism	0.000	0.876	0.124
E77.1 Defects in glycoprotein degradation	0.000	0.876	0.124
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.876	0.124
E84.9 Cystic fibrosis, unspecified	0.000	0.876	0.124
E84.8 Cystic fibrosis with other manifestations	0.000	0.876	0.124
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.876	0.124
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.876	0.124
E11 Non-insulin-dependent diabetes mellitus	0.000	0.876	0.124
E83.4 Disorders of magnesium metabolism	0.000	0.877	0.123
E89.4 Postprocedural ovarian failure	0.000	0.877	0.123
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.877	0.123
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.877	0.123
E89.5 Postprocedural testicular hypofunction	0.000	0.877	0.123
E89.1 Postprocedural hypoinsulinaemia	0.000	0.877	0.123
E80.6 Other disorders of bilirubin metabolism	0.000	0.879	0.121
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.884	0.116
E67 Other hyperalimentation	0.000	0.886	0.114
E68 Sequelae of hyperalimentation	0.000	0.886	0.114
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.887	0.113
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.888	0.112
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.888	0.112
E79.1 Lesch-Nyhan syndrome	0.000	0.888	0.112
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.891	0.109
E44.1 Mild protein-energy malnutrition	0.000	0.896	0.104
E44.0 Moderate protein-energy malnutrition	0.000	0.896	0.104
E16.1 Other hypoglycaemia	0.000	0.899	0.101
E87.3 Alkalosis	0.000	0.900	0.100
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.900	0.099
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.900	0.099
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.900	0.099
E74.2 Disorders of galactose metabolism	0.000	0.900	0.099
E74.1 Disorders of fructose metabolism	0.000	0.900	0.099
E11.5 With peripheral circulatory complications	0.000	0.901	0.099
E00-E07 Disorders of thyroid gland	0.000	0.901	0.099
K90.9 Intestinal malabsorption, unspecified	0.001	0.903	0.097
E11.0 With coma	0.000	0.903	0.097
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.904	0.096
E78.4 Other hyperlipidaemia	0.000	0.906	0.094
E11.8 With unspecified complications	0.000	0.907	0.093
E74.0 Glycogen storage disease	0.000	0.908	0.091
E73.8 Other lactose intolerance	0.000	0.909	0.091
E73.1 Secondary lactase deficiency	0.000	0.909	0.091
E73.0 Congenital lactase deficiency	0.000	0.909	0.091
E87.0 Hyperosmolality and hypernatraemia	0.000	0.909	0.091
E11.2 With renal complications	0.000	0.910	0.090
E11.7 With multiple complications	0.000	0.911	0.089
E78.6 Lipoprotein deficiency	0.000	0.912	0.088
E11.1 With ketoacidosis	0.000	0.912	0.088
E87.7 Fluid overload	0.000	0.913	0.087
E11.6 With other specified complications	0.000	0.915	0.085
E78.3 Hyperchylomicronaemia	0.000	0.917	0.083
E83.5 Disorders of calcium metabolism	0.000	0.917	0.083
E87.2 Acidosis	0.000	0.917	0.083
E50-E64 Other nutritional deficiencies	0.000	0.918	0.082
E67.8 Other specified hyperalimentation	0.000	0.918	0.082
E67.3 Hypervitaminosis D	0.000	0.918	0.082
E67.2 Megavitamin-B6 syndrome	0.000	0.918	0.082
E67.1 Hypercarotenaemia	0.000	0.918	0.082
E67.0 Hypervitaminosis A	0.000	0.918	0.082
E78.1 Pure hyperglyceridaemia	0.000	0.921	0.079
E87.4 Mixed disorder of acid-base balance	0.000	0.921	0.079
E11.4 With neurological complications	0.000	0.921	0.079
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.922	0.078
E07 Other disorders of thyroid	0.000	0.923	0.077
E89.3 Postprocedural hypopituitarism	0.000	0.923	0.077
E78.2 Mixed hyperlipidaemia	0.000	0.924	0.076
E04 Other non-toxic goitre	0.000	0.926	0.074
E20-E35 Disorders of other endocrine glands	0.000	0.928	0.072
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.928	0.071
E00 Congenital iodine-deficiency syndrome	0.000	0.928	0.071
E87.5 Hyperkalaemia	0.000	0.930	0.070
E11.3 With ophthalmic complications	0.000	0.932	0.068
E06 Thyroiditis	0.000	0.933	0.067
E04.9 Non-toxic goitre, unspecified	0.000	0.935	0.065
E07.9 Disorder of thyroid, unspecified	0.000	0.936	0.064
E03 Other hypothyroidism	0.000	0.938	0.062
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.941	0.059
E63 Other nutritional deficiencies	0.000	0.941	0.059
E56 Other vitamin deficiencies	0.000	0.941	0.059
E50 Vitamin A deficiency	0.000	0.941	0.059
E60 Dietary zinc deficiency	0.000	0.941	0.059
E59 Dietary selenium deficiency	0.000	0.941	0.059
E54 Ascorbic acid deficiency	0.000	0.941	0.059
E52 Niacin deficiency [pellagra]	0.000	0.941	0.059
E58 Dietary calcium deficiency	0.000	0.941	0.058
E14.9 Without complications	0.000	0.941	0.059
E04.0 Non-toxic diffuse goitre	0.000	0.944	0.056
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.944	0.056
E07.1 Dyshormogenetic goitre	0.000	0.945	0.055
E07.0 Hypersecretion of calcitonin	0.000	0.945	0.055
E28 Ovarian dysfunction	0.000	0.945	0.055
E53 Deficiency of other B group vitamins	0.000	0.945	0.055
E20 Hypoparathyroidism	0.000	0.945	0.055
E03.8 Other specified hypothyroidism	0.000	0.945	0.055
E51 Thiamine deficiency	0.000	0.945	0.054
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.945	0.054
E26 Hyperaldosteronism	0.000	0.946	0.054
E04.8 Other specified non-toxic goitre	0.000	0.947	0.053
E23 Hypofunction and other disorders of pituitary gland	0.000	0.948	0.052
E29 Testicular dysfunction	0.000	0.948	0.052
E66 Obesity	0.000	0.948	0.052
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.948	0.052
E32 Diseases of thymus	0.000	0.948	0.052
E31 Polyglandular dysfunction	0.000	0.948	0.052
E30 Disorders of puberty, not elsewhere classified	0.000	0.948	0.052
E25 Adrenogenital disorders	0.000	0.948	0.052
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.948	0.051
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.948	0.051
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.948	0.051
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.948	0.051
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.948	0.051
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.948	0.051
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.948	0.051
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.948	0.051
E78.8 Other disorders of lipoprotein metabolism	0.000	0.950	0.049
E28.2 Polycystic ovarian syndrome	0.000	0.951	0.049
E07.8 Other specified disorders of thyroid	0.000	0.951	0.049
E06.3 Autoimmune thyroiditis	0.000	0.951	0.049
E06.5 Other chronic thyroiditis	0.000	0.952	0.048
E06.4 Drug-induced thyroiditis	0.000	0.952	0.048
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.952	0.048
E06.1 Subacute thyroiditis	0.000	0.952	0.048
E06.0 Acute thyroiditis	0.000	0.952	0.048
E23.2 Diabetes insipidus	0.000	0.952	0.048
E04.2 Non-toxic multinodular goitre	0.000	0.952	0.048
E34 Other endocrine disorders	0.000	0.953	0.047
E24 Cushing's syndrome	0.000	0.953	0.047
E55 Vitamin D deficiency	0.000	0.953	0.047
E73.9 Lactose intolerance, unspecified	0.001	0.954	0.045
E03.5 Myxoedema coma	0.000	0.955	0.044
E03.4 Atrophy of thyroid (acquired)	0.000	0.955	0.044
E03.3 Postinfectious hypothyroidism	0.000	0.955	0.044
E03.1 Congenital hypothyroidism without goitre	0.000	0.955	0.044
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.955	0.044
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.956	0.044
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.956	0.043
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.956	0.044
E27 Other disorders of adrenal gland	0.000	0.956	0.043
E50.9 Vitamin A deficiency, unspecified	0.000	0.957	0.042
E50.8 Other manifestations of vitamin A deficiency	0.000	0.957	0.042
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.957	0.042
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.957	0.042
E50.5 Vitamin A deficiency with night blindness	0.000	0.957	0.042
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.957	0.042
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.957	0.042
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.957	0.042
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.957	0.042
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.957	0.042
E56.9 Vitamin deficiency, unspecified	0.000	0.957	0.042
E56.8 Deficiency of other vitamins	0.000	0.957	0.042
E56.1 Deficiency of vitamin K	0.000	0.957	0.042
E56.0 Deficiency of vitamin E	0.000	0.957	0.042
E63.9 Nutritional deficiency, unspecified	0.000	0.957	0.042
E63.8 Other specified nutritional deficiencies	0.000	0.957	0.042
E63.1 Imbalance of constituents of food intake	0.000	0.957	0.042
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.957	0.042
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.957	0.042
E64.8 Sequelae of other nutritional deficiencies	0.000	0.957	0.042
E64.3 Sequelae of rickets	0.000	0.957	0.042
E64.2 Sequelae of vitamin C deficiency	0.000	0.957	0.042
E64.1 Sequelae of vitamin A deficiency	0.000	0.957	0.042
E64.0 Sequelae of protein-energy malnutrition	0.000	0.957	0.042
E20.9 Hypoparathyroidism, unspecified	0.000	0.957	0.042
E06.9 Thyroiditis, unspecified	0.000	0.958	0.042
E26.0 Primary hyperaldosteronism	0.000	0.959	0.041
E27.1 Primary adrenocortical insufficiency	0.000	0.959	0.041
E28.9 Ovarian dysfunction, unspecified	0.000	0.960	0.040
E28.8 Other ovarian dysfunction	0.000	0.960	0.040
E28.1 Androgen excess	0.000	0.960	0.040
E28.0 Oestrogen excess	0.000	0.960	0.040
E53.1 Pyridoxine deficiency	0.000	0.960	0.039
E53.0 Riboflavin deficiency	0.000	0.960	0.039
E20.8 Other hypoparathyroidism	0.000	0.960	0.039
E20.1 Pseudohypoparathyroidism	0.000	0.960	0.039
E20.0 Idiopathic hypoparathyroidism	0.000	0.960	0.039
E51.9 Thiamine deficiency, unspecified	0.000	0.961	0.039
E51.8 Other manifestations of thiamine deficiency	0.000	0.961	0.039
E51.1 Beriberi	0.000	0.961	0.039
E53.9 Vitamin B deficiency, unspecified	0.000	0.961	0.039
E24.2 Drug-induced Cushing's syndrome	0.000	0.961	0.039
E26.9 Hyperaldosteronism, unspecified	0.000	0.961	0.039
E26.8 Other hyperaldosteronism	0.000	0.961	0.039
E26.1 Secondary hyperaldosteronism	0.000	0.961	0.039
E23.7 Disorder of pituitary gland, unspecified	0.000	0.962	0.038
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.962	0.038
E23.1 Drug-induced hypopituitarism	0.000	0.962	0.038
E29.1 Testicular hypofunction	0.000	0.962	0.038
E29.9 Testicular dysfunction, unspecified	0.000	0.962	0.037
E29.8 Other testicular dysfunction	0.000	0.962	0.037
E29.0 Testicular hyperfunction	0.000	0.962	0.037
E66.1 Drug-induced obesity	0.000	0.963	0.037
E25.9 Adrenogenital disorder, unspecified	0.000	0.963	0.037
E25.8 Other adrenogenital disorders	0.000	0.963	0.037
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.963	0.037
E30.9 Disorder of puberty, unspecified	0.000	0.963	0.037
E30.8 Other disorders of puberty	0.000	0.963	0.037
E30.1 Precocious puberty	0.000	0.963	0.037
E30.0 Delayed puberty	0.000	0.963	0.037
E31.9 Polyglandular dysfunction, unspecified	0.000	0.963	0.037
E31.8 Other polyglandular dysfunction	0.000	0.963	0.037
E31.1 Polyglandular hyperfunction	0.000	0.963	0.037
E31.0 Autoimmune polyglandular failure	0.000	0.963	0.037
E32.9 Disease of thymus, unspecified	0.000	0.963	0.037
E32.8 Other diseases of thymus	0.000	0.963	0.037
E32.1 Abscess of thymus	0.000	0.963	0.037
E32.0 Persistent hyperplasia of thymus	0.000	0.963	0.037
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.963	0.037
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.963	0.037
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.963	0.037
E04.1 Non-toxic single thyroid nodule	0.000	0.963	0.037
E53.8 Deficiency of other specified B group vitamins	0.000	0.964	0.036
E51.2 Wernicke's encephalopathy	0.000	0.965	0.034
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.965	0.035
E66.0 Obesity due to excess calories	0.000	0.966	0.034
E34.5 Androgen resistance syndrome	0.000	0.966	0.034
E34.4 Constitutional tall stature	0.000	0.966	0.034
E34.3 Short stature, not elsewhere classified	0.000	0.966	0.034
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.966	0.034
E34.1 Other hypersecretion of intestinal hormones	0.000	0.966	0.034
E24.8 Other Cushing's syndrome	0.000	0.966	0.034
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.966	0.034
E24.3 Ectopic ACTH syndrome	0.000	0.966	0.034
E24.1 Nelson's syndrome	0.000	0.966	0.034
E55.0 Rickets, active	0.000	0.966	0.034
E34.9 Endocrine disorder, unspecified	0.000	0.966	0.034
E05.8 Other thyrotoxicosis	0.000	0.967	0.033
E23.6 Other disorders of pituitary gland	0.000	0.967	0.033
E34.8 Other specified endocrine disorders	0.000	0.967	0.033
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.967	0.033
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.968	0.032
E05.5 Thyroid crisis or storm	0.000	0.968	0.032
E05.4 Thyrotoxicosis factitia	0.000	0.968	0.032
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.968	0.032
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.968	0.032
E27.5 Adrenomedullary hyperfunction	0.000	0.969	0.031
E27.0 Other adrenocortical overactivity	0.000	0.969	0.031
E61 Deficiency of other nutrient elements	0.001	0.969	0.030
E34.0 Carcinoid syndrome	0.000	0.969	0.031
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.969	0.030
E24.0 Pituitary-dependent Cushing's disease	0.000	0.970	0.030
E28.3 Primary ovarian failure	0.000	0.974	0.025
E86 Volume depletion	0.000	0.976	0.024
E27.2 Addisonian crisis	0.000	0.976	0.024
E24.9 Cushing's syndrome, unspecified	0.000	0.976	0.024
E21.3 Hyperparathyroidism, unspecified	0.000	0.976	0.024
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.976	0.024
E21.4 Other specified disorders of parathyroid gland	0.000	0.976	0.023
E21.2 Other hyperparathyroidism	0.000	0.976	0.023
E22 Hyperfunction of pituitary gland	0.000	0.977	0.023
E61.9 Deficiency of nutrient element, unspecified	0.001	0.977	0.022
E61.8 Deficiency of other specified nutrient elements	0.001	0.977	0.022
E61.7 Deficiency of multiple nutrient elements	0.001	0.977	0.022
E61.6 Vanadium deficiency	0.001	0.977	0.022
E61.5 Molybdenum deficiency	0.001	0.977	0.022
E61.4 Chromium deficiency	0.001	0.977	0.022
E61.3 Manganese deficiency	0.001	0.977	0.022
E61.0 Copper deficiency	0.001	0.977	0.022
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.978	0.022
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.978	0.022
E55.9 Vitamin D deficiency, unspecified	0.000	0.979	0.021
E27.8 Other specified disorders of adrenal gland	0.000	0.979	0.020
K90-K93 Other diseases of the digestive system	0.000	0.980	0.020
E23.0 Hypopituitarism	0.000	0.981	0.019
E27.9 Disorder of adrenal gland, unspecified	0.000	0.981	0.018
E61.2 Magnesium deficiency	0.001	0.982	0.017
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.983	0.017
E22.8 Other hyperfunction of pituitary gland	0.000	0.983	0.017
E66.9 Obesity, unspecified	0.000	0.984	0.016
E22.1 Hyperprolactinaemia	0.000	0.985	0.015
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.985	0.014
E87.6 Hypokalaemia	0.000	0.986	0.014
C71.2 Temporal lobe	0.013	0.987	0.000
C71 Malignant neoplasm of brain	0.012	0.988	0.000
E21.0 Primary hyperparathyroidism	0.000	0.988	0.012
C71.9 Brain, unspecified	0.012	0.988	0.000
R31 Unspecified haematuria	0.011	0.989	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.989	0.011
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.989	0.011
K93.1 Megacolon in Chagas' disease	0.000	0.989	0.011
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.989	0.011
C71.3 Parietal lobe	0.010	0.990	0.000
M41.9 Scoliosis, unspecified	0.010	0.990	0.000
C71.1 Frontal lobe	0.010	0.990	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.010	0.990	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.990	0.010
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.010	0.990	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.010	0.990	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.010	0.990	0.000
C71.7 Brain stem	0.009	0.991	0.000
G44.2 Tension-type headache	0.009	0.991	0.000
C71.6 Cerebellum	0.009	0.991	0.000
C71.5 Cerebral ventricle	0.009	0.991	0.000
C71.0 Cerebrum, except lobes and ventricles	0.009	0.991	0.000
G31.8 Other specified degenerative diseases of nervous system	0.000	0.991	0.009
C71.8 Overlapping lesion of brain	0.009	0.991	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.001	0.991	0.008
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.992	0.008
E61.1 Iron deficiency	0.001	0.992	0.006
C71.4 Occipital lobe	0.008	0.992	0.000
E66.8 Other obesity	0.000	0.992	0.008
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.008	0.992	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.008	0.992	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.008	0.992	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.008	0.992	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.008	0.992	0.000
G31.0 Circumscribed brain atrophy	0.000	0.992	0.008
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.993	0.007
N04.9 Unspecified	0.000	0.993	0.007
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.007	0.993	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.007	0.993	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.007	0.993	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.994	0.006
M79.10 Myalgia (Multiple sites)	0.006	0.994	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.006	0.994	0.000
C69 Malignant neoplasm of eye and adnexa	0.006	0.994	0.000
C70 Malignant neoplasm of meninges	0.005	0.995	0.000
M41 Scoliosis	0.005	0.995	0.000
C69.9 Eye, unspecified	0.005	0.995	0.000
G31.2 Degeneration of nervous system due to alcohol	0.000	0.995	0.005
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.005	0.995	0.000
G30-G32 Other degenerative diseases of the nervous system	0.000	0.995	0.005
G44 Other headache syndromes	0.005	0.995	0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.005	0.995	0.000
M67.8 Other specified disorders of synovium and tendon	0.000	0.995	0.005
G30 Alzheimer's disease	0.000	0.995	0.005
R52.1 Chronic intractable pain	0.005	0.995	0.000
C70.0 Cerebral meninges	0.004	0.995	0.000
K22.8 Other specified diseases of oesophagus	0.005	0.995	0.000
C69.3 Choroid	0.004	0.996	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.996	0.004
G44.8 Other specified headache syndromes	0.004	0.996	0.000
C69.8 Overlapping lesion of eye and adnexa	0.004	0.996	0.000
C69.5 Lachrymal gland and duct	0.004	0.996	0.000
C69.4 Ciliary body	0.004	0.996	0.000
C69.2 Retina	0.004	0.996	0.000
C69.1 Cornea	0.004	0.996	0.000
C69.6 Orbit	0.004	0.996	0.000
G30.0 Alzheimer's disease with early onset	0.000	0.996	0.004
C69.0 Conjunctiva	0.004	0.996	0.000
M79.19 Myalgia (Site unspecified)	0.004	0.996	0.000
C70.9 Meninges, unspecified	0.004	0.996	0.000
C70.1 Spinal meninges	0.004	0.996	0.000
I31.9 Disease of pericardium, unspecified	0.000	0.996	0.004
G30.9 Alzheimer's disease, unspecified	0.000	0.996	0.004
M41.5 Other secondary scoliosis	0.004	0.996	0.000
M41.4 Neuromuscular scoliosis	0.004	0.996	0.000
M41.3 Thoracogenic scoliosis	0.004	0.996	0.000
M41.2 Other idiopathic scoliosis	0.004	0.996	0.000
M41.1 Juvenile idiopathic scoliosis	0.004	0.996	0.000
M41.0 Infantile idiopathic scoliosis	0.004	0.996	0.000
N50.1 Vascular disorders of male genital organs	0.000	0.996	0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations