TreeWAS – Variant ID: rs10234581

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10.3 With ophthalmic complications	0.044	0.956	0.000
E10 Insulin-dependent diabetes mellitus	0.043	0.957	0.000
E10.4 With neurological complications	0.041	0.959	0.000
E10.0 With coma	0.039	0.961	0.000
E10.2 With renal complications	0.038	0.961	0.000
E10.5 With peripheral circulatory complications	0.036	0.964	0.000
E10.6 With other specified complications	0.035	0.965	0.000
E10.7 With multiple complications	0.035	0.965	0.000
E10.8 With unspecified complications	0.029	0.971	0.000
E10.1 With ketoacidosis	0.027	0.973	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.000	0.978	0.022
D73.0 Hyposplenism	0.021	0.979	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.000	0.986	0.014
D73 Diseases of spleen	0.009	0.991	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.009	0.991	0.000
G47.9 Sleep disorder, unspecified	0.009	0.991	0.000
N02.9 Unspecified	0.008	0.992	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.992	0.008
G31.8 Other specified degenerative diseases of nervous system	0.000	0.992	0.008
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.992	0.008
D73.3 Abscess of spleen	0.008	0.992	0.000
G91.1 Obstructive hydrocephalus	0.008	0.992	0.000
D73.1 Hypersplenism	0.007	0.992	0.000
G31.0 Circumscribed brain atrophy	0.000	0.993	0.007
D73.4 Cyst of spleen	0.007	0.993	0.000
D73.9 Disease of spleen, unspecified	0.007	0.993	0.000
D73.2 Chronic congestive splenomegaly	0.007	0.993	0.000
G91 Hydrocephalus	0.007	0.993	0.000
G91.8 Other hydrocephalus	0.007	0.993	0.000
D73.5 Infarction of spleen	0.007	0.993	0.000
N02 Recurrent and persistent haematuria	0.007	0.993	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.006	0.994	0.000
G47 Sleep disorders	0.006	0.994	0.000
M48.02 Spinal stenosis (Cervical region)	0.006	0.994	0.000
G91.0 Communicating hydrocephalus	0.006	0.994	0.000
G91.2 Normal-pressure hydrocephalus	0.006	0.994	0.000
E10.9 Without complications	0.006	0.994	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.994	0.006
N02.8 Other	0.006	0.994	0.000
A87.9 Viral meningitis, unspecified	0.006	0.994	0.000
D73.8 Other diseases of spleen	0.005	0.994	0.000
G91.9 Hydrocephalus, unspecified	0.006	0.994	0.000
N28.8 Other specified disorders of kidney and ureter	0.006	0.994	0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.005	0.995	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.005	0.995	0.000
N02.0 Minor glomerular abnormality	0.005	0.995	0.000
N18.0 End-stage renal disease	0.005	0.995	0.000
G31.2 Degeneration of nervous system due to alcohol	0.000	0.995	0.005
N02.7 Diffuse crescentic glomerulonephritis	0.005	0.995	0.000
N02.6 Dense deposit disease	0.005	0.995	0.000
N02.5 Diffuse mesangiocapillary glomerulonephritis	0.005	0.995	0.000
N02.4 Diffuse endocapillary proliferative glomerulonephritis	0.005	0.995	0.000
N02.3 Diffuse mesangial proliferative glomerulonephritis	0.005	0.995	0.000
N02.1 Focal and segmental glomerular lesions	0.005	0.995	0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified	0.000	0.995	0.005
M19.94 Arthrosis, unspecified (Hand)	0.000	0.995	0.005
N02.2 Diffuse membranous glomerulonephritis	0.005	0.995	0.000
G47.8 Other sleep disorders	0.005	0.995	0.000
G47.4 Narcolepsy and cataplexy	0.005	0.995	0.000
R52.9 Pain, unspecified	0.004	0.996	0.000
H18.8 Other specified disorders of cornea	0.000	0.996	0.004
N00-N08 Glomerular diseases	0.004	0.996	0.000
E10-E14 Diabetes mellitus	0.004	0.996	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.004	0.996	0.000
N05.8 Other	0.004	0.996	0.000
N05 Unspecified nephritic syndrome	0.004	0.996	0.000
M19.97 Arthrosis, unspecified (Ankle and foot)	0.004	0.996	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.004	0.996	0.000
G47.2 Disorders of the sleep-wake schedule	0.004	0.996	0.000
S82.00 Fracture of patella (closed)	0.004	0.996	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.000	0.996	0.004
N04 Nephrotic syndrome	0.004	0.996	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.004	0.996	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.003	0.996	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.003	0.996	0.000
R94.3 Abnormal results of cardiovascular function studies	0.000	0.996	0.004
N08 Glomerular disorders in diseases classified elsewhere	0.003	0.997	0.000
B07 Viral warts	0.000	0.997	0.003
N00 Acute nephritic syndrome	0.003	0.997	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.003	0.997	0.000
N06 Isolated proteinuria with specified morphological lesion	0.003	0.997	0.000
N01 Rapidly progressive nephritic syndrome	0.003	0.997	0.000
E12 Malnutrition-related diabetes mellitus	0.003	0.997	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.003	0.997	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.003	0.997	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.003	0.997	0.000
N04.9 Unspecified	0.003	0.997	0.000
E13 Other specified diabetes mellitus	0.003	0.997	0.000
N04.0 Minor glomerular abnormality	0.003	0.997	0.000
N05.6 Dense deposit disease	0.003	0.997	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.003	0.997	0.000
N05.0 Minor glomerular abnormality	0.003	0.997	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.003	0.997	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.003	0.997	0.000
A87 Viral meningitis	0.003	0.997	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.003	0.997	0.000
E29.1 Testicular hypofunction	0.003	0.997	0.000
G47.3 Sleep apnoea	0.003	0.997	0.000
N05.2 Diffuse membranous glomerulonephritis	0.003	0.997	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.003	0.997	0.000
N04.8 Other	0.003	0.997	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.003	0.997	0.000
N04.6 Dense deposit disease	0.003	0.997	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.003	0.997	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.003	0.997	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.003	0.997	0.000
M54.36 Sciatica (Lumbar region)	0.000	0.997	0.003
E13.3 With ophthalmic complications	0.003	0.997	0.000
E28.2 Polycystic ovarian syndrome	0.003	0.997	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.003	0.997	0.000
N08.8 Glomerular disorders in other diseases classified elsewhere	0.003	0.997	0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.003	0.997	0.000
N08.1 Glomerular disorders in neoplastic diseases	0.003	0.997	0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
N04.2 Diffuse membranous glomerulonephritis	0.003	0.997	0.000
N04.1 Focal and segmental glomerular lesions	0.003	0.997	0.000
N05.1 Focal and segmental glomerular lesions	0.003	0.997	0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.003	0.997	0.000
N00.9 Unspecified	0.003	0.997	0.000
N00.8 Other	0.002	0.997	0.000
N00.7 Diffuse crescentic glomerulonephritis	0.002	0.997	0.000
N00.6 Dense deposit disease	0.002	0.997	0.000
N00.5 Diffuse mesangiocapillary glomerulonephritis	0.002	0.997	0.000
N00.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.997	0.000
N00.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.997	0.000
N00.2 Diffuse membranous glomerulonephritis	0.002	0.997	0.000
N00.1 Focal and segmental glomerular lesions	0.002	0.997	0.000
N00.0 Minor glomerular abnormality	0.002	0.997	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.003	0.997	0.000
N01.9 Unspecified	0.002	0.997	0.000
N01.8 Other	0.002	0.997	0.000
N01.7 Diffuse crescentic glomerulonephritis	0.002	0.997	0.000
N01.6 Dense deposit disease	0.002	0.997	0.000
N01.5 Diffuse mesangiocapillary glomerulonephritis	0.002	0.997	0.000
N01.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.997	0.000
N01.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.997	0.000
N01.2 Diffuse membranous glomerulonephritis	0.002	0.997	0.000
N01.1 Focal and segmental glomerular lesions	0.002	0.997	0.000
N01.0 Minor glomerular abnormality	0.002	0.997	0.000
N06.9 Unspecified	0.002	0.997	0.000
N06.8 Other	0.002	0.997	0.000
N06.7 Diffuse crescentic glomerulonephritis	0.002	0.997	0.000
N06.6 Dense deposit disease	0.002	0.997	0.000
N06.5 Diffuse mesangiocapillary glomerulonephritis	0.002	0.997	0.000
N06.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.997	0.000
N06.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.997	0.000
N06.2 Diffuse membranous glomerulonephritis	0.002	0.997	0.000
N06.1 Focal and segmental glomerular lesions	0.002	0.997	0.000
N06.0 Minor glomerular abnormality	0.002	0.997	0.000
N07.9 Unspecified	0.002	0.997	0.000
N07.8 Other	0.002	0.997	0.000
N07.7 Diffuse crescentic glomerulonephritis	0.002	0.997	0.000
N07.6 Dense deposit disease	0.002	0.997	0.000
N07.5 Diffuse mesangiocapillary glomerulonephritis	0.002	0.997	0.000
N07.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.997	0.000
N07.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.997	0.000
N07.2 Diffuse membranous glomerulonephritis	0.002	0.997	0.000
N07.1 Focal and segmental glomerular lesions	0.002	0.997	0.000
N07.0 Minor glomerular abnormality	0.002	0.997	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.003	0.997	0.000
E12.9 Without complications	0.002	0.997	0.000
E12.8 With unspecified complications	0.002	0.997	0.000
E12.7 With multiple complications	0.002	0.997	0.000
E12.6 With other specified complications	0.002	0.997	0.000
E12.5 With peripheral circulatory complications	0.002	0.997	0.000
E12.4 With neurological complications	0.002	0.997	0.000
E12.3 With ophthalmic complications	0.002	0.997	0.000
E12.2 With renal complications	0.002	0.997	0.000
E12.1 With ketoacidosis	0.002	0.997	0.000
E12.0 With coma	0.002	0.997	0.000
N75.0 Cyst of Bartholin's gland	0.003	0.997	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.003	0.997	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.003	0.997	0.000
M06.9 Rheumatoid arthritis, unspecified	0.003	0.997	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.002	0.997	0.000
E13.8 With unspecified complications	0.002	0.997	0.000
E13.7 With multiple complications	0.002	0.997	0.000
E13.6 With other specified complications	0.002	0.997	0.000
E13.5 With peripheral circulatory complications	0.002	0.997	0.000
E13.4 With neurological complications	0.002	0.997	0.000
E13.2 With renal complications	0.002	0.997	0.000
E13.1 With ketoacidosis	0.002	0.997	0.000
E13.0 With coma	0.002	0.997	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.002	0.997	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.002	0.997	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.002	0.997	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.997	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.002	0.997	0.000
N05.9 Unspecified	0.002	0.997	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.002
A87.8 Other viral meningitis	0.002	0.997	0.000
A87.2 Lymphocytic choriomeningitis	0.002	0.997	0.000
A87.1 Adenoviral meningitis	0.002	0.997	0.000
A87.0 Enteroviral meningitis	0.002	0.997	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.002	0.998	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
G30-G32 Other degenerative diseases of the nervous system	0.000	0.998	0.002
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M05 Seropositive rheumatoid arthritis	0.002	0.998	0.000
H02.3 Blepharochalasis	0.002	0.998	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.002	0.998	0.000
H53.8 Other visual disturbances	0.000	0.998	0.002
N03 Chronic nephritic syndrome	0.002	0.998	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.002	0.998	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.002	0.998	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.998	0.002
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.002	0.998	0.000
C18.4 Transverse colon	0.000	0.998	0.002
M05.8 Other seropositive rheumatoid arthritis	0.002	0.998	0.000
M24.07 Loose body in joint (Ankle and foot)	0.002	0.998	0.000
N08.5 Glomerular disorders in systemic connective tissue disorders	0.002	0.998	0.000
E29 Testicular dysfunction	0.002	0.998	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.002	0.998	0.000
I72.4 Aneurysm of artery of lower extremity	0.002	0.998	0.000
E34.8 Other specified endocrine disorders	0.002	0.998	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
E28 Ovarian dysfunction	0.002	0.998	0.000
I72.3 Aneurysm of iliac artery	0.002	0.998	0.000
Z98.2 Presence of cerebrospinal fluid drainage device	0.002	0.998	0.000
E13.9 Without complications	0.002	0.998	0.000
E34.9 Endocrine disorder, unspecified	0.002	0.998	0.000
K22.2 Oesophageal obstruction	0.002	0.998	0.000
N03.8 Other	0.002	0.998	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.002	0.998	0.000
M05.2 Rheumatoid vasculitis	0.002	0.998	0.000
M05.1 Rheumatoid lung disease	0.002	0.998	0.000
M05.0 Felty's syndrome	0.002	0.998	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.998	0.002
E34 Other endocrine disorders	0.002	0.998	0.000
I05.9 Mitral valve disease, unspecified	0.002	0.998	0.000
N03.7 Diffuse crescentic glomerulonephritis	0.002	0.998	0.000
N03.6 Dense deposit disease	0.002	0.998	0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.998	0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.998	0.000
N03.2 Diffuse membranous glomerulonephritis	0.002	0.998	0.000
N03.0 Minor glomerular abnormality	0.002	0.998	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.000	0.998	0.002
G04 Encephalitis, myelitis and encephalomyelitis	0.002	0.998	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.002	0.998	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.002	0.998	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.002	0.998	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.002	0.998	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.002	0.998	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.002	0.998	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.002	0.998	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.002	0.998	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.002	0.998	0.000
E24.2 Drug-induced Cushing's syndrome	0.002	0.998	0.000
I72.8 Aneurysm of other specified arteries	0.002	0.998	0.000
N03.1 Focal and segmental glomerular lesions	0.002	0.998	0.000
S01.5 Open wound of lip and oral cavity	0.000	0.998	0.002
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.998	0.002
C18.9 Colon, unspecified	0.000	0.998	0.002
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.002	0.998	0.000
E29.9 Testicular dysfunction, unspecified	0.002	0.998	0.000
E29.8 Other testicular dysfunction	0.002	0.998	0.000
E29.0 Testicular hyperfunction	0.002	0.998	0.000
E24 Cushing's syndrome	0.002	0.998	0.000
Z47.8 Other specified orthopaedic follow-up care	0.002	0.998	0.000
I72 Other aneurysm	0.002	0.998	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.002	0.998	0.000
Z88.3 Personal history of allergy to other anti-infective agents	0.002	0.998	0.000
B50.9 Plasmodium falciparum malaria, unspecified	0.002	0.998	0.000
M10.0 Idiopathic gout	0.002	0.998	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
M10.00 Idiopathic gout (Multiple sites)	0.002	0.998	0.000
M85.0 Fibrous dysplasia (monostotic)	0.002	0.998	0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis	0.002	0.998	0.000
E28.9 Ovarian dysfunction, unspecified	0.002	0.998	0.000
E28.8 Other ovarian dysfunction	0.002	0.998	0.000
E28.1 Androgen excess	0.002	0.998	0.000
E28.0 Oestrogen excess	0.002	0.998	0.000
T23.2 Burn of second degree of wrist and hand	0.002	0.998	0.000
N83.3 Acquired atrophy of ovary and Fallopian tube	0.000	0.998	0.002
M54.89 Other dorsalgia (Site unspecified)	0.002	0.998	0.000
E24.0 Pituitary-dependent Cushing's disease	0.002	0.998	0.000
M10.04 Idiopathic gout (Hand)	0.002	0.998	0.000
M14.6 Neuropathic arthropathy	0.002	0.998	0.000
M10.06 Idiopathic gout (Lower leg)	0.002	0.998	0.000
K86.3 Pseudocyst of pancreas	0.002	0.998	0.000
M05.09 Felty's syndrome (Site unspecified)	0.001	0.998	0.000
M05.08 Felty's syndrome (Other)	0.001	0.998	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.001	0.998	0.000
M05.06 Felty's syndrome (Lower leg)	0.001	0.998	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.001	0.998	0.000
M05.04 Felty's syndrome (Hand)	0.001	0.998	0.000
M05.03 Felty's syndrome (Forearm)	0.001	0.998	0.000
M05.02 Felty's syndrome (Upper arm)	0.001	0.998	0.000
M05.01 Felty's syndrome (Shoulder region)	0.001	0.998	0.000
M05.00 Felty's syndrome (Multiple sites)	0.001	0.998	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.001	0.998	0.000
M05.18 Rheumatoid lung disease (Other)	0.001	0.998	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.001	0.998	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.001	0.998	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.001	0.998	0.000
M05.14 Rheumatoid lung disease (Hand)	0.001	0.998	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.001	0.998	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.001	0.998	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.001	0.998	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.001	0.998	0.000
M05.28 Rheumatoid vasculitis (Other)	0.001	0.998	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.001	0.998	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.001	0.998	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.001	0.998	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.001	0.998	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.001	0.998	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.001	0.998	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.001	0.998	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.001	0.998	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.001	0.998	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.001	0.998	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.001	0.998	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.001	0.998	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.001	0.998	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.001	0.998	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.001	0.998	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.001	0.998	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.001	0.998	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.001	0.998	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
E34.5 Androgen resistance syndrome	0.002	0.998	0.000
E34.4 Constitutional tall stature	0.002	0.998	0.000
E34.3 Short stature, not elsewhere classified	0.002	0.998	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.002	0.998	0.000
E34.1 Other hypersecretion of intestinal hormones	0.002	0.998	0.000
H57.0 Anomalies of pupillary function	0.002	0.998	0.000
O00.1 Tubal pregnancy	0.000	0.998	0.002
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.001	0.998	0.000
C49.9 Connective and soft tissue, unspecified	0.000	0.998	0.002
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.002	0.998	0.000
G04.1 Tropical spastic paraplegia	0.002	0.998	0.000
G04.0 Acute disseminated encephalitis	0.002	0.998	0.000
Z76.3 Healthy person accompanying sick person	0.002	0.998	0.000
M10.09 Idiopathic gout (Site unspecified)	0.002	0.998	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
E24.9 Cushing's syndrome, unspecified	0.002	0.998	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.000	0.998	0.001
N28.0 Ischaemia and infarction of kidney	0.002	0.998	0.000
E28.3 Primary ovarian failure	0.002	0.998	0.000
H35.9 Retinal disorder, unspecified	0.002	0.998	0.000
I72.0 Aneurysm of carotid artery	0.002	0.998	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.998	0.002
K65.8 Other peritonitis	0.002	0.998	0.000
G37 Other demyelinating diseases of central nervous system	0.002	0.998	0.000
E24.8 Other Cushing's syndrome	0.001	0.998	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.001	0.998	0.000
E24.3 Ectopic ACTH syndrome	0.001	0.998	0.000
E24.1 Nelson's syndrome	0.001	0.998	0.000
R17 Unspecified jaundice	0.000	0.998	0.002
I72.6 Aneurysm and dissection of vertebral artery	0.002	0.998	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.002	0.998	0.000
E20-E35 Disorders of other endocrine glands	0.002	0.998	0.000
M10.07 Idiopathic gout (Ankle and foot)	0.002	0.998	0.000
E23.0 Hypopituitarism	0.002	0.998	0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.998	0.001
M10.08 Idiopathic gout (Other)	0.001	0.998	0.000
M10.05 Idiopathic gout (Pelvic region and thigh)	0.001	0.998	0.000
M10.03 Idiopathic gout (Forearm)	0.001	0.998	0.000
M10.02 Idiopathic gout (Upper arm)	0.001	0.998	0.000
M10.01 Idiopathic gout (Shoulder region)	0.001	0.998	0.000
M25.37 Other instability of joint (Ankle and foot)	0.002	0.998	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.002	0.998	0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.001	0.998	0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.001	0.998	0.000
B59 Pneumocystosis	0.002	0.998	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
I72.2 Aneurysm of renal artery	0.001	0.998	0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.001	0.998	0.000
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.001	0.998	0.000
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.001	0.998	0.000
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.001	0.998	0.000
G30 Alzheimer's disease	0.000	0.998	0.001
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.001	0.998	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.001	0.998	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.001	0.998	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.001	0.998	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.001	0.998	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.001	0.998	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.001	0.998	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.001	0.998	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.001	0.998	0.000
M85.66 Other cyst of bone (Lower leg)	0.001	0.998	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.002	0.998	0.000
C49.0 Connective and soft tissue of head, face and neck	0.000	0.998	0.002
G37.8 Other specified demyelinating diseases of central nervous system	0.001	0.998	0.000
I72.9 Aneurysm of unspecified site	0.001	0.998	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.998	0.002
S82.0 Fracture of patella	0.002	0.998	0.000
S99.8 Other specified injuries of ankle and foot	0.002	0.998	0.000
T45.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.002	0.998	0.000
E34.0 Carcinoid syndrome	0.001	0.998	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.001	0.998	0.000
M85.64 Other cyst of bone (Hand)	0.001	0.998	0.000
I05.1 Rheumatic mitral insufficiency	0.002	0.998	0.000
I72.1 Aneurysm of artery of upper extremity	0.001	0.998	0.000
O14.9 Preeclampsia, unspecified	0.000	0.998	0.002
M85.68 Other cyst of bone (Other)	0.001	0.998	0.000
C49.3 Connective and soft tissue of thorax	0.000	0.998	0.001
C69.0 Conjunctiva	0.001	0.998	0.000
D69.6 Thrombocytopenia, unspecified	0.000	0.998	0.002
M14 Arthropathies in other diseases classified elsewhere	0.001	0.998	0.000
M12.57 Traumatic arthropathy (Ankle and foot)	0.001	0.998	0.000
D23.4 Skin of scalp and neck	0.000	0.998	0.002
F02.0 Dementia in Pick's disease	0.000	0.998	0.001
F50.0 Anorexia nervosa	0.001	0.998	0.000
M85.6 Other cyst of bone	0.001	0.998	0.000
B50 Plasmodium falciparum malaria	0.001	0.998	0.000
E25 Adrenogenital disorders	0.001	0.998	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.001	0.998	0.000
M12.5 Traumatic arthropathy	0.001	0.998	0.000
M12 Other specific arthropathies	0.001	0.998	0.000
M85.20 Hyperostosis of skull-Mult sites	0.001	0.999	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.000	0.999	0.001
M12.24 Villonodular synovitis (pigmented) (Hand)	0.001	0.999	0.000
G37.5 Concentric sclerosis [Balo]	0.001	0.999	0.000
G37.4 Subacute necrotising myelitis	0.001	0.999	0.000
G37.2 Central pontine myelinolysis	0.001	0.999	0.000
G37.1 Central demyelination of corpus callosum	0.001	0.999	0.000
G37.0 Diffuse sclerosis	0.001	0.999	0.000
M12.2 Villonodular synovitis (pigmented)	0.001	0.999	0.000
M89.0 Algoneurodystrophy	0.001	0.999	0.000
E14 Unspecified diabetes mellitus	0.001	0.999	0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.001	0.999	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.001	0.999	0.000
E32 Diseases of thymus	0.001	0.999	0.000
E30 Disorders of puberty, not elsewhere classified	0.001	0.999	0.000
M10.39 Gout due to impairment of renal function (Site unspecified)	0.001	0.999	0.000
C49.1 Connective and soft tissue of upper limb, including shoulder	0.000	0.999	0.001
E27.8 Other specified disorders of adrenal gland	0.001	0.999	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.001	0.999	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.001	0.999	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.001	0.999	0.000
M85.2 Hyperostosis of skull	0.001	0.999	0.000
S99.9 Unspecified injury of ankle and foot	0.001	0.999	0.000
E31 Polyglandular dysfunction	0.001	0.999	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.001	0.999	0.000
H40.2 Primary angle-closure glaucoma	0.000	0.999	0.001
H43.3 Other vitreous opacities	0.000	0.999	0.001
M10.3 Gout due to impairment of renal function	0.001	0.999	0.000
Q05.9 Spina bifida, unspecified	0.001	0.999	0.000
I05 Rheumatic mitral valve diseases	0.001	0.999	0.000
M06 Other rheumatoid arthritis	0.001	0.999	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.001	0.999	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.001	0.999	0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube	0.000	0.999	0.001
R82.8 Abnormal findings on cytological and histological examination of urine	0.000	0.999	0.001
M10 Gout	0.001	0.999	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.001	0.999	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.001	0.999	0.001
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.001	0.999	0.000
M89.03 Algoneurodystrophy (Forearm)	0.001	0.999	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.001	0.999	0.000
I05.0 Mitral stenosis	0.001	0.999	0.000
M06.8 Other specified rheumatoid arthritis	0.001	0.999	0.000
M12.3 Palindromic rheumatism	0.001	0.999	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.001	0.999	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.001	0.999	0.000
M14.4 Arthropathy in amyloidosis	0.001	0.999	0.000
M14.3 Lipoid dermatoarthritis	0.001	0.999	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.001	0.999	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.001	0.999	0.000
E23 Hypofunction and other disorders of pituitary gland	0.001	0.999	0.000
M85.69 Other cyst of bone (Site unspecified)	0.001	0.999	0.000
M85.63 Other cyst of bone (Forearm)	0.001	0.999	0.000
M85.62 Other cyst of bone (Upper arm)	0.001	0.999	0.000
M85.61 Other cyst of bone (Shoulder region)	0.001	0.999	0.000
M85.60 Other cyst of bone (Multiple sites)	0.001	0.999	0.000
M89.04 Algoneurodystrophy (Hand)	0.001	0.999	0.000
B02.9 Zoster without complication	0.000	0.999	0.001
B50.8 Other severe and complicated Plasmodium falciparum malaria	0.001	0.999	0.000
B50.0 Plasmodium falciparum malaria with cerebral complications	0.001	0.999	0.000
C45.9 Mesothelioma, unspecified	0.000	0.999	0.001
E14.4 With neurological complications	0.001	0.999	0.000
E25.9 Adrenogenital disorder, unspecified	0.001	0.999	0.000
E25.8 Other adrenogenital disorders	0.001	0.999	0.000
G30.9 Alzheimer's disease, unspecified	0.000	0.999	0.001
G30.1 Alzheimer's disease with late onset	0.000	0.999	0.001
H72.0 Central perforation of tympanic membrane	0.000	0.999	0.001
M89.5 Osteolysis	0.001	0.999	0.000
N17.0 Acute renal failure with tubular necrosis	0.001	0.999	0.000
D05 Carcinoma in situ of breast	0.000	0.999	0.001
M85 Other disorders of bone density and structure	0.001	0.999	0.000
Q05 Spina bifida	0.001	0.999	0.000
M12.59 Traumatic arthropathy (Site unspecified)	0.001	0.999	0.000
M12.58 Traumatic arthropathy (Other)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations