TreeWAS – Variant ID: rs10254284

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E11.9 Without complications	0.000	0.320	0.680
E11 Non-insulin-dependent diabetes mellitus	0.000	0.324	0.676
E11.4 With neurological complications	0.000	0.331	0.669
E11.3 With ophthalmic complications	0.000	0.338	0.662
E11.8 With unspecified complications	0.000	0.382	0.618
E11.2 With renal complications	0.000	0.466	0.534
E11.7 With multiple complications	0.000	0.557	0.443
E11.5 With peripheral circulatory complications	0.000	0.608	0.392
E11.0 With coma	0.000	0.624	0.376
E11.6 With other specified complications	0.000	0.662	0.338
E11.1 With ketoacidosis	0.000	0.695	0.305
E10-E14 Diabetes mellitus	0.000	0.906	0.094
E12 Malnutrition-related diabetes mellitus	0.000	0.932	0.068
E10 Insulin-dependent diabetes mellitus	0.000	0.934	0.066
E10.8 With unspecified complications	0.000	0.939	0.060
E10.2 With renal complications	0.000	0.942	0.058
E10.0 With coma	0.000	0.944	0.056
E10.5 With peripheral circulatory complications	0.000	0.950	0.050
E10.7 With multiple complications	0.000	0.951	0.049
E12.9 Without complications	0.000	0.951	0.049
E12.8 With unspecified complications	0.000	0.951	0.049
E12.7 With multiple complications	0.000	0.951	0.049
E12.6 With other specified complications	0.000	0.951	0.049
E12.5 With peripheral circulatory complications	0.000	0.951	0.049
E12.4 With neurological complications	0.000	0.951	0.049
E12.3 With ophthalmic complications	0.000	0.951	0.049
E12.2 With renal complications	0.000	0.951	0.049
E12.1 With ketoacidosis	0.000	0.951	0.049
E12.0 With coma	0.000	0.951	0.049
E13 Other specified diabetes mellitus	0.000	0.951	0.049
E10.4 With neurological complications	0.000	0.952	0.048
J33.0 Polyp of nasal cavity	0.000	0.957	0.043
E10.6 With other specified complications	0.000	0.958	0.042
E13.8 With unspecified complications	0.000	0.965	0.035
E13.7 With multiple complications	0.000	0.965	0.035
E13.6 With other specified complications	0.000	0.965	0.035
E13.5 With peripheral circulatory complications	0.000	0.965	0.035
E13.4 With neurological complications	0.000	0.965	0.035
E13.2 With renal complications	0.000	0.965	0.035
E13.1 With ketoacidosis	0.000	0.965	0.035
E13.0 With coma	0.000	0.965	0.035
E66.9 Obesity, unspecified	0.034	0.966	0.000
E66 Obesity	0.033	0.967	0.000
E13.3 With ophthalmic complications	0.000	0.967	0.032
E66.8 Other obesity	0.032	0.968	0.000
E10.9 Without complications	0.000	0.969	0.031
J33 Nasal polyp	0.000	0.970	0.030
E14 Unspecified diabetes mellitus	0.000	0.971	0.029
E66.2 Extreme obesity with alveolar hypoventilation	0.028	0.972	0.000
J33.9 Nasal polyp, unspecified	0.000	0.973	0.027
E66.0 Obesity due to excess calories	0.027	0.973	0.000
J33.8 Other polyp of sinus	0.000	0.975	0.025
E14.8 With unspecified complications	0.000	0.976	0.024
E66.1 Drug-induced obesity	0.024	0.976	0.000
E14.2 Withrenal complications	0.000	0.976	0.023
M19.90 Arthrosis, unspecified (Multiple sites)	0.000	0.978	0.022
E14.4 With neurological complications	0.000	0.978	0.022
E13.9 Without complications	0.000	0.979	0.021
E14.6 With other specified complications	0.000	0.979	0.021
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.021	0.979	0.000
E14.7 With multiple complications	0.000	0.979	0.021
J33.1 Polypoid sinus degeneration	0.000	0.979	0.021
E14.1 With ketoacidosis	0.000	0.979	0.021
N13 Obstructive and reflux uropathy	0.020	0.980	0.000
N13.6 Pyonephrosis	0.018	0.981	0.000
E14.0 With coma	0.000	0.982	0.018
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.018	0.982	0.000
E10.3 With ophthalmic complications	0.000	0.982	0.017
E14.5 With peripheral circulatory complications	0.000	0.983	0.017
N13.8 Other obstructive and reflux uropathy	0.017	0.983	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.016	0.984	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.000	0.984	0.016
N10-N16 Renal tubulo-interstitial diseases	0.016	0.984	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.015	0.985	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.015	0.985	0.000
M48.0 Spinal stenosis	0.000	0.985	0.015
N13.7 Vesicoureteral-reflux-associated uropathy	0.014	0.986	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.000	0.986	0.014
M48.5 Collapsed vertebra, not elsewhere classified	0.000	0.986	0.014
M48.09 Spinal stenosis (Site unspecified)	0.000	0.986	0.014
M48 Other spondylopathies	0.000	0.986	0.014
N13.9 Obstructive and reflux uropathy, unspecified	0.013	0.987	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.013	0.987	0.000
N11 Chronic tubulo-interstitial nephritis	0.013	0.987	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.000	0.988	0.012
M48.04 Spinal stenosis (Thoracic region)	0.000	0.988	0.012
N13.3 Other and unspecified hydronephrosis	0.012	0.988	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.000	0.988	0.012
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.000	0.988	0.012
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.011	0.989	0.000
C44.3 Skin of other and unspecified parts of face	0.011	0.989	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.011	0.989	0.000
R21 Rash and other nonspecific skin eruption	0.000	0.989	0.011
N11.1 Chronic obstructive pyelonephritis	0.011	0.989	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.000	0.989	0.011
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.000	0.989	0.011
M48.9 Spondylopathy, unspecified	0.000	0.989	0.011
Z63.4 Disappearance and death of family member	0.011	0.989	0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.000	0.989	0.011
Z63 Other problems related to primary support group, including family circumstances	0.011	0.989	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.011	0.989	0.000
N10 Acute tubulo-interstitial nephritis	0.010	0.990	0.000
Z56 Problems related to employment and unemployment	0.010	0.990	0.000
N15 Other renal tubulo-interstitial diseases	0.010	0.990	0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.000	0.990	0.010
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.000	0.990	0.010
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.000	0.990	0.010
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.000	0.990	0.010
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.000	0.990	0.010
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.000	0.990	0.010
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.010	0.990	0.000
M48.4 Fatigue fracture of vertebra	0.000	0.990	0.010
M48.3 Traumatic spondylopathy	0.000	0.990	0.010
M48.2 Kissing spine	0.000	0.990	0.010
M48.1 Ankylosing hyperostosis [Forestier]	0.000	0.990	0.010
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.990	0.010
M48.06 Spinal stenosis (Lumbar region)	0.000	0.990	0.010
R63.8 Other symptoms and signs concerning food and fluid intake	0.000	0.990	0.010
Z56.6 Other physical and mental strain related to work	0.010	0.990	0.000
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.009	0.990	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.009	0.990	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.009	0.990	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.009	0.990	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.009	0.990	0.000
Z56.0 Unemployment, unspecified	0.010	0.990	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.009	0.990	0.000
E65-E68 Obesity and other hyperalimentation	0.009	0.990	0.001
M48.8 Other specified spondylopathies	0.000	0.990	0.009
N11.8 Other chronic tubulo-interstitial nephritis	0.009	0.990	0.000
Z61 Problems related to negative life events in childhood	0.009	0.991	0.000
Z63.0 Problems in relationship with spouse or partner	0.009	0.991	0.000
Z57 Occupational exposure to risk-factors	0.009	0.991	0.000
S32.0 Fracture of lumbar vertebra	0.000	0.991	0.009
Z63.6 Dependent relative needing care at home	0.009	0.991	0.000
E10.1 With ketoacidosis	0.001	0.991	0.008
M48.00 Spinal stenosis (Multiple sites in spine)	0.000	0.991	0.009
Z58 Problems related to physical environment	0.009	0.991	0.000
S32 Fracture of lumbar spine and pelvis	0.000	0.991	0.009
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.008	0.991	0.000
E14.3 With ophthalmic complications	0.000	0.991	0.008
S32.3 Fracture of ilium	0.000	0.991	0.008
M48.92 Spondylopathy, unspecified (Cervical region)	0.000	0.992	0.008
S32.30 Fracture of ilium (closed)	0.000	0.992	0.008
M48.96 Spondylopathy, unspecified (Lumbar region)	0.000	0.992	0.008
S32.4 Fracture of acetabulum	0.000	0.992	0.008
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.000	0.992	0.008
N14.4 Toxic nephropathy, not elsewhere classified	0.008	0.992	0.000
N14.3 Nephropathy induced by heavy metals	0.008	0.992	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.008	0.992	0.000
N14.0 Analgesic nephropathy	0.008	0.992	0.000
S32.40 Fracture of acetabulum (closed)	0.000	0.992	0.008
S62.50 Fracture of thumb (closed)	0.000	0.992	0.008
Z61.6 Problems related to alleged physical abuse of child	0.008	0.992	0.000
C44.4 Skin of scalp and neck	0.008	0.992	0.000
R91 Abnormal findings on diagnostic imaging of lung	0.008	0.992	0.000
Z64 Problems related to certain psychosocial circumstances	0.008	0.992	0.000
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.992	0.008
M48.97 Spondylopathy, unspecified (Lumbosacral region)	0.000	0.992	0.008
M48.95 Spondylopathy, unspecified (Thoracolumbar region)	0.000	0.992	0.008
M48.94 Spondylopathy, unspecified (Thoracic region)	0.000	0.992	0.008
M48.93 Spondylopathy, unspecified (Cervicothoracic region)	0.000	0.992	0.008
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.992	0.008
M48.90 Spondylopathy, unspecified (Multiple sites in spine)	0.000	0.992	0.008
Z63.7 Other stressful life events affecting family and household	0.008	0.992	0.000
Z63.9 Problem related to primary support group, unspecified	0.008	0.992	0.000
Z63.3 Absence of family member	0.008	0.992	0.000
Z63.2 Inadequate family support	0.008	0.992	0.000
Z63.1 Problems in relationship with parents and in-laws	0.008	0.992	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.008	0.992	0.000
Z62 Other problems related to upbringing	0.008	0.992	0.000
Z55 Problems related to education and literacy	0.008	0.992	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.008	0.992	0.000
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.008	0.992	0.000
Z60 Problems related to social environment	0.008	0.992	0.000
Z59 Problems related to housing and economic circumstances	0.008	0.992	0.000
Z56.5 Uncongenial work	0.008	0.992	0.000
Z56.4 Discord with boss and workmates	0.008	0.992	0.000
Z56.2 Threat of job loss	0.008	0.992	0.000
Z56.1 Change of job	0.008	0.992	0.000
M48.99 Spondylopathy, unspecified (Site unspecified)	0.000	0.992	0.008
N15.1 Renal and perinephric abscess	0.008	0.992	0.000
Z56.7 Other and unspecified problems related to employment	0.008	0.992	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.000	0.992	0.008
N15.8 Other specified renal tubulo-interstitial diseases	0.007	0.992	0.000
N15.0 Balkan nephropathy	0.007	0.992	0.000
Z58.5 Exposure to other pollution	0.007	0.992	0.000
M48.87 Other specified spondylopathies (Lumbosacral region)	0.000	0.992	0.007
Z57.8 Occupational exposure to other risk-factors	0.007	0.992	0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)	0.000	0.993	0.007
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)	0.000	0.993	0.007
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)	0.000	0.993	0.007
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)	0.000	0.993	0.007
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)	0.000	0.993	0.007
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)	0.000	0.993	0.007
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)	0.000	0.993	0.007
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)	0.000	0.993	0.007
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)	0.000	0.993	0.007
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)	0.000	0.993	0.007
M48.29 Kissing spine (Site unspecified)	0.000	0.993	0.007
M48.28 Kissing spine (Sacral and sacrococcygeal region)	0.000	0.993	0.007
M48.27 Kissing spine (Lumbosacral region)	0.000	0.993	0.007
M48.26 Kissing spine (Lumbar region)	0.000	0.993	0.007
M48.25 Kissing spine (Thoracolumbar region)	0.000	0.993	0.007
M48.24 Kissing spine (Thoracic region)	0.000	0.993	0.007
M48.23 Kissing spine (Cervicothoracic region)	0.000	0.993	0.007
M48.22 Kissing spine (Cervical region)	0.000	0.993	0.007
M48.21 Kissing spine (Occipito-atlanto-axial region)	0.000	0.993	0.007
M48.20 Kissing spine (Multiple sites in spine)	0.000	0.993	0.007
M48.39 Traumatic spondylopathy (Site unspecified)	0.000	0.993	0.007
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)	0.000	0.993	0.007
M48.37 Traumatic spondylopathy (Lumbosacral region)	0.000	0.993	0.007
M48.36 Traumatic spondylopathy (Lumbar region)	0.000	0.993	0.007
M48.35 Traumatic spondylopathy (Thoracolumbar region)	0.000	0.993	0.007
M48.34 Traumatic spondylopathy (Thoracic region)	0.000	0.993	0.007
M48.33 Traumatic spondylopathy (Cervicothoracic region)	0.000	0.993	0.007
M48.32 Traumatic spondylopathy (Cervical region)	0.000	0.993	0.007
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)	0.000	0.993	0.007
M48.30 Traumatic spondylopathy (Multiple sites in spine)	0.000	0.993	0.007
M48.49 Fatigue fracture of vertebra (Site unspecified)	0.000	0.993	0.007
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)	0.000	0.993	0.007
M48.47 Fatigue fracture of vertebra (Lumbosacral region)	0.000	0.993	0.007
M48.46 Fatigue fracture of vertebra (Lumbar region)	0.000	0.993	0.007
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)	0.000	0.993	0.007
M48.44 Fatigue fracture of vertebra (Thoracic region)	0.000	0.993	0.007
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)	0.000	0.993	0.007
M48.42 Fatigue fracture of vertebra (Cervical region)	0.000	0.993	0.007
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)	0.000	0.993	0.007
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)	0.000	0.993	0.007
Z58.8 Other problems related to physical environment	0.007	0.993	0.000
Z65 Problems related to other psychosocial circumstances	0.007	0.993	0.000
M48.86 Other specified spondylopathies (Lumbar region)	0.000	0.993	0.007
S61.1 Open wound of finger(s) with damage to nail	0.000	0.993	0.007
Z60.9 Problem related to social environment, unspecified	0.007	0.993	0.000
E67 Other hyperalimentation	0.007	0.993	0.001
E68 Sequelae of hyperalimentation	0.007	0.993	0.001
M48.89 Other specified spondylopathies (Site unspecified)	0.000	0.993	0.007
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.000	0.993	0.007
M48.84 Other specified spondylopathies (Thoracic region)	0.000	0.993	0.007
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.000	0.993	0.007
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.000	0.993	0.007
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.000	0.993	0.007
S32.5 Fracture of pubis	0.000	0.993	0.007
Z61.9 Negative life events in childhood, unspecified	0.007	0.993	0.000
Z61.8 Other negative life events in childhood	0.007	0.993	0.000
Z61.7 Personal frightening experience in childhood	0.007	0.993	0.000
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.007	0.993	0.000
Z61.3 Events resulting in loss of self-esteem in childhood	0.007	0.993	0.000
Z61.2 Altered pattern of family relationships in childhood	0.007	0.993	0.000
Z61.1 Removal from home in childhood	0.007	0.993	0.000
Z61.0 Loss of love relationship in childhood	0.007	0.993	0.000
Z56.3 Stressful work schedule	0.007	0.993	0.000
Z57.2 Occupational exposure to dust	0.007	0.993	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.000	0.993	0.007
Z57.9 Occupational exposure to unspecified risk-factor	0.007	0.993	0.000
Z57.7 Occupational exposure to vibration	0.007	0.993	0.000
Z57.6 Occupational exposure to extreme temperature	0.007	0.993	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.007	0.993	0.000
Z57.1 Occupational exposure to radiation	0.007	0.993	0.000
Z57.0 Occupational exposure to noise	0.007	0.993	0.000
S32.01 Fracture of lumbar vertebra (open)	0.000	0.993	0.007
C44.0 Skin of lip	0.007	0.993	0.000
Z58.7 Exposure to tobacco smoke	0.007	0.993	0.000
Z57.3 Occupational exposure to other air contaminants	0.007	0.993	0.000
Z58.9 Problem related to physical environment, unspecified	0.007	0.993	0.000
Z58.6 Inadequate drinking-water supply	0.007	0.993	0.000
Z58.4 Exposure to radiation	0.007	0.993	0.000
Z58.3 Exposure to soil pollution	0.007	0.993	0.000
Z58.2 Exposure to water pollution	0.007	0.993	0.000
Z58.0 Exposure to noise	0.007	0.993	0.000
S62.70 Multiple fractures of fingers (closed)	0.000	0.993	0.007
Z63.5 Disruption of family by separation and divorce	0.006	0.993	0.000
M48.82 Other specified spondylopathies (Cervical region)	0.000	0.993	0.006
S32.2 Fracture of coccyx	0.000	0.993	0.006
Z58.1 Exposure to air pollution	0.006	0.993	0.000
Z60.8 Other problems related to social environment	0.006	0.993	0.000
Z59.0 Homelessness	0.006	0.994	0.000
S32.31 Fracture of ilium (open)	0.000	0.994	0.006
O02.1 Missed abortion	0.006	0.994	0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.000	0.994	0.006
S62.5 Fracture of thumb	0.000	0.994	0.006
S32.41 Fracture of acetabulum (open)	0.000	0.994	0.006
S32.1 Fracture of sacrum	0.000	0.994	0.006
M45-M49 Spondylopathies	0.000	0.994	0.006
M46 Other inflammatory spondylopathies	0.000	0.994	0.006
M48.02 Spinal stenosis (Cervical region)	0.000	0.994	0.006
Z64.0 Problems related to unwanted pregnancy	0.006	0.994	0.000
Z64.4 Discord with counsellors	0.006	0.994	0.000
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.006	0.994	0.000
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.006	0.994	0.000
Z64.1 Problems related to multiparity	0.006	0.994	0.000
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.006	0.994	0.000
Z55.9 Problems relating to education and literacy, unspecified	0.006	0.994	0.000
Z55.8 Other problems relating to education and literacy	0.006	0.994	0.000
Z55.4 Educational maladjustment and discord with teachers and classmates	0.006	0.994	0.000
Z55.3 Underachievement in school	0.006	0.994	0.000
Z55.2 Failed examinations	0.006	0.994	0.000
Z55.1 Schooling unavailable and unattainable	0.006	0.994	0.000
Z55.0 Illiteracy and low-level literacy	0.006	0.994	0.000
Z62.9 Problem related to upbringing, unspecified	0.006	0.994	0.000
Z62.8 Other specified problems related to upbringing	0.006	0.994	0.000
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.006	0.994	0.000
Z62.5 Other problems related to neglect in upbringing	0.006	0.994	0.000
Z62.4 Emotional neglect of child	0.006	0.994	0.000
Z62.3 Hostility towards and scapegoating of child	0.006	0.994	0.000
Z62.2 Institutional upbringing	0.006	0.994	0.000
Z62.1 Parental overprotection	0.006	0.994	0.000
Z62.0 Inadequate parental supervision and control	0.006	0.994	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.006	0.994	0.000
Z65.9 Problem related to unspecified psychosocial circumstances	0.006	0.994	0.000
Z60.5 Target of perceived adverse discrimination and persecution	0.006	0.994	0.000
Z60.4 Social exclusion and rejection	0.006	0.994	0.000
Z60.3 Acculturation difficulty	0.006	0.994	0.000
Z60.1 Atypical parenting situation	0.006	0.994	0.000
Z60.0 Problems of adjustment to life-cycle transitions	0.006	0.994	0.000
S32.50 Fracture of pubis (closed)	0.000	0.994	0.006
Z59.7 Insufficient social insurance and welfare support	0.006	0.994	0.000
Z59.6 Low income	0.006	0.994	0.000
Z59.5 Extreme poverty	0.006	0.994	0.000
Z59.4 Lack of adequate food	0.006	0.994	0.000
Z59.3 Problems related to living in residential institution	0.006	0.994	0.000
S62.7 Multiple fractures of fingers	0.000	0.994	0.006
Z59.2 Discord with neighbours, lodgers and landlord	0.006	0.994	0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.000	0.994	0.006
M46.4 Discitis, unspecified	0.000	0.994	0.006
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.000	0.994	0.006
Z65.5 Exposure to disaster, war and other hostilities	0.005	0.994	0.000
Z65.4 Victim of crime and terrorism	0.005	0.994	0.000
Z65.2 Problems related to release from prison	0.005	0.994	0.000
Z65.1 Imprisonment and other incarceration	0.005	0.994	0.000
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.005	0.994	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.000	0.994	0.005
Z59.8 Other problems relating to housing and economic circumstances	0.005	0.994	0.000
Z65.8 Other specified problems related to psychosocial circumstances	0.005	0.994	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.000	0.994	0.005
C44 Other malignant neoplasms of skin	0.005	0.995	0.000
S62 Fracture at wrist and hand level	0.000	0.995	0.005
E67.8 Other specified hyperalimentation	0.005	0.995	0.001
E67.3 Hypervitaminosis D	0.005	0.995	0.001
E67.2 Megavitamin-B6 syndrome	0.005	0.995	0.001
E67.1 Hypercarotenaemia	0.005	0.995	0.001
E67.0 Hypervitaminosis A	0.005	0.995	0.001
M46.2 Osteomyelitis of vertebra	0.000	0.995	0.005
S32.51 Fracture of pubis (open)	0.000	0.995	0.005
Z59.1 Inadequate housing	0.005	0.995	0.000
N13.4 Hydroureter	0.005	0.995	0.000
Z63.8 Other specified problems related to primary support group	0.005	0.995	0.000
S32.21 Fracture of coccyx (open)	0.000	0.995	0.005
S32.20 Fracture of coccyx (closed)	0.000	0.995	0.005
M46.3 Infection of intervertebral disk (pyogenic)	0.000	0.995	0.005
M46.26 Osteomyelitis of vertebra (Lumbar region)	0.000	0.995	0.005
M46.40 Discitis, unspecified (Multiple sites in spine)	0.000	0.995	0.005
S52.00 Fracture of upper end of ulna (closed)	0.000	0.995	0.005
E65 Localised adiposity	0.004	0.995	0.001
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.995	0.005
M46.47 Discitis, unspecified (Lumbosacral region)	0.000	0.995	0.005
S32.11 Fracture of sacrum (open)	0.000	0.995	0.005
Z65.3 Problems related to other legal circumstances	0.004	0.995	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.000	0.995	0.005
M46.8 Other specified inflammatory spondylopathies	0.000	0.995	0.005
M46.5 Other infective spondylopathies	0.000	0.995	0.005
M46.49 Discitis, unspecified (Site unspecified)	0.000	0.995	0.005
M45 Ankylosing spondylitis	0.000	0.995	0.005
M46.0 Spinal enthesopathy	0.000	0.995	0.004
M46.1 Sacro-iliitis, not elsewhere classified	0.000	0.995	0.004
S62.8 Fracture of other and unspecified parts of wrist and hand	0.000	0.995	0.004
M49 Spondylopathies in diseases classified elsewhere	0.000	0.995	0.004
S32.10 Fracture of sacrum (closed)	0.000	0.996	0.004
M46.42 Discitis, unspecified (Cervical region)	0.000	0.996	0.004
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)	0.000	0.996	0.004
M46.45 Discitis, unspecified (Thoracolumbar region)	0.000	0.996	0.004
M46.43 Discitis, unspecified (Cervicothoracic region)	0.000	0.996	0.004
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)	0.000	0.996	0.004
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.000	0.996	0.004
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.996	0.004
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.000	0.996	0.004
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.000	0.996	0.004
S62.1 Fracture of other carpal bone(s)	0.000	0.996	0.004
C44.8 Overlapping lesion of skin	0.004	0.996	0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.996	0.004
C44.1 Skin of eyelid, including canthus	0.004	0.996	0.000
M46.29 Osteomyelitis of vertebra (Site unspecified)	0.000	0.996	0.004
M46.28 Osteomyelitis of vertebra (Sacral and sacrococcygeal region)	0.000	0.996	0.004
M46.27 Osteomyelitis of vertebra (Lumbosacral region)	0.000	0.996	0.004
M46.25 Osteomyelitis of vertebra (Thoracolumbar region)	0.000	0.996	0.004
M46.23 Osteomyelitis of vertebra (Cervicothoracic region)	0.000	0.996	0.004
M46.22 Osteomyelitis of vertebra (Cervical region)	0.000	0.996	0.004
M46.21 Osteomyelitis of vertebra (Occipito-atlanto-axial region)	0.000	0.996	0.004
M46.20 Osteomyelitis of vertebra (Multiple sites in spine)	0.000	0.996	0.004
M46.24 Osteomyelitis of vertebra (Thoracic region)	0.000	0.996	0.004
S62.4 Multiple fractures of metacarpal bones	0.000	0.996	0.004
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.004	0.996	0.000
M46.36 Infection of intervertebral disc (pyogenic) (Lumbar region)	0.000	0.996	0.004
S62.61 Fracture of other finger (open)	0.000	0.996	0.004
I67.8 Other specified cerebrovascular diseases	0.000	0.996	0.004
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.996	0.004
O02 Other abnormal products of conception	0.004	0.996	0.000
S62.51 Fracture of thumb (open)	0.000	0.996	0.004
S62.71 Multiple fractures of fingers (open)	0.000	0.996	0.004
S62.6 Fracture of other finger	0.000	0.996	0.004
O02.0 Blighted ovum and nonhydatidiform mole	0.004	0.996	0.000
M46.34 Infection of intervertebral disc (pyogenic) (Thoracic region)	0.000	0.996	0.004
L85.9 Epidermal thickening, unspecified	0.000	0.996	0.004
M46.39 Infection of intervertebral disc (pyogenic) (Site unspecified)	0.000	0.996	0.004
M46.38 Infection of intervertebral disc (pyogenic) (Sacral and sacrococcygeal region)	0.000	0.996	0.004
M46.37 Infection of intervertebral disc (pyogenic) (Lumbosacral region)	0.000	0.996	0.004
M46.35 Infection of intervertebral disc (pyogenic) (Thoracolumbar region)	0.000	0.996	0.004
M46.33 Infection of intervertebral disc (pyogenic) (Cervicothoracic region)	0.000	0.996	0.004
M46.32 Infection of intervertebral disc (pyogenic) (Cervical region)	0.000	0.996	0.004
M46.31 Infection of intervertebral disc (pyogenic) (Occipito-atlanto-axial region)	0.000	0.996	0.004
M46.30 Infection of intervertebral disc (pyogenic) (Multiple sites in spine)	0.000	0.996	0.004
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.000	0.996	0.004
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.000	0.996	0.004
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.000	0.996	0.004
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.996	0.004
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.000	0.996	0.004
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.996	0.004
M46.59 Other infective spondylopathies (Site unspecified)	0.000	0.996	0.003
M46.58 Other infective spondylopathies (Sacral and sacrococcygeal region)	0.000	0.996	0.003
M46.57 Other infective spondylopathies (Lumbosacral region)	0.000	0.996	0.003
M46.56 Other infective spondylopathies (Lumbar region)	0.000	0.996	0.003
M46.55 Other infective spondylopathies (Thoracolumbar region)	0.000	0.996	0.003
M46.54 Other infective spondylopathies (Thoracic region)	0.000	0.996	0.003
M46.53 Other infective spondylopathies (Cervicothoracic region)	0.000	0.996	0.003
M46.52 Other infective spondylopathies (Cervical region)	0.000	0.996	0.003
M46.51 Other infective spondylopathies (Occipito-atlanto-axial region)	0.000	0.996	0.003
M46.50 Other infective spondylopathies (Multiple sites in spine)	0.000	0.996	0.003
M46.89 Other specified inflammatory spondylopathies (Site unspecified)	0.000	0.996	0.003
M46.88 Other specified inflammatory spondylopathies (Sacral and sacrococcygeal region)	0.000	0.996	0.003
M46.87 Other specified inflammatory spondylopathies (Lumbosacral region)	0.000	0.996	0.003
M46.86 Other specified inflammatory spondylopathies (Lumbar region)	0.000	0.996	0.003
M46.85 Other specified inflammatory spondylopathies (Thoracolumbar region)	0.000	0.996	0.003
M46.84 Other specified inflammatory spondylopathies (Thoracic region)	0.000	0.996	0.003
M46.83 Other specified inflammatory spondylopathies (Cervicothoracic region)	0.000	0.996	0.003
M46.82 Other specified inflammatory spondylopathies (Cervical region)	0.000	0.996	0.003
M46.81 Other specified inflammatory spondylopathies (Occipito-atlanto-axial region)	0.000	0.996	0.003
M46.80 Other specified inflammatory spondylopathies (Multiple sites in spine)	0.000	0.996	0.003
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.996	0.004
M46.44 Discitis, unspecified (Thoracic region)	0.000	0.996	0.003
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.004	0.996	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.996	0.003
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.996	0.003
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.996	0.003
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.996	0.003
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.996	0.003
M46.09 Spinal enthesopathy (Site unspecified)	0.000	0.996	0.003
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)	0.000	0.996	0.003
M46.07 Spinal enthesopathy (Lumbosacral region)	0.000	0.996	0.003
M46.05 Spinal enthesopathy (Thoracolumbar region)	0.000	0.996	0.003
M46.04 Spinal enthesopathy (Thoracic region)	0.000	0.996	0.003
M46.03 Spinal enthesopathy (Cervicothoracic region)	0.000	0.996	0.003
M46.02 Spinal enthesopathy (Cervical region)	0.000	0.996	0.003
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)	0.000	0.996	0.003
M46.00 Spinal enthesopathy (Multiple sites in spine)	0.000	0.996	0.003
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.996	0.003
M46.16 Sacroiliitis, not elsewhere classified-Lumbar	0.000	0.996	0.003
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar	0.000	0.996	0.003
M46.14 Sacroiliitis, not elsewhere classified-Thoracic	0.000	0.996	0.003
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic	0.000	0.996	0.003
M46.12 Sacroiliitis, not elsewhere classified-Cervical	0.000	0.996	0.003
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl	0.000	0.996	0.003
M46.10 Sacroiliitis, not elsewhere classified-Mult site	0.000	0.996	0.003
I95.2 Hypotension due to drugs	0.004	0.996	0.000
M49.8 Spondylopathy in other diseases classified elsewhere	0.000	0.996	0.003
M49.4 Neuropathic spondylopathy	0.000	0.996	0.003
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.000	0.996	0.003
M49.2 Enterobacterial spondylitis	0.000	0.996	0.003
M49.1 Brucella spondylitis	0.000	0.996	0.003
M49.0 Tuberculosis of spine	0.000	0.996	0.003
S62.3 Fracture of other metacarpal bone	0.000	0.996	0.003
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ	0.000	0.997	0.003
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.000	0.997	0.003
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral	0.000	0.997	0.003
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.997	0.003
M46.06 Spinal enthesopathy (Lumbar region)	0.000	0.997	0.003
M46.19 Sacroiliitis, not elsewhere classified-Site unspe	0.000	0.997	0.003
S62.11 Fracture of other carpal bone(s) (open)	0.000	0.997	0.003
S62.10 Fracture of other carpal bone(s) (closed)	0.000	0.997	0.003
Q50.4 Embryonic cyst of Fallopian tube	0.003	0.997	0.000
S62.2 Fracture of first metacarpal bone	0.000	0.997	0.003
S62.41 Multiple fractures of metacarpal bones (open)	0.000	0.997	0.003
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.000	0.997	0.003
L57.0 Actinic keratosis	0.003	0.997	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.000	0.997	0.003
C25.0 Head of pancreas	0.000	0.997	0.003
O02.8 Other specified abnormal products of conception	0.003	0.997	0.000
S62.40 Multiple fractures of metacarpal bones (closed)	0.000	0.997	0.003
O02.9 Abnormal product of conception, unspecified	0.003	0.997	0.000
Q51.3 Bicornate uterus	0.000	0.997	0.003
E29.1 Testicular hypofunction	0.003	0.997	0.000
E14.9 Without complications	0.000	0.997	0.003
F17.2 Dependence syndrome	0.003	0.997	0.000
K51.2 Ulcerative (chronic) proctitis	0.003	0.997	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.997	0.003
M49.09 Tuberculosis of spine (Site unspecified)	0.000	0.997	0.003
M49.08 Tuberculosis of spine (Sacral and sacrococcygeal region)	0.000	0.997	0.003
M49.07 Tuberculosis of spine (Lumbosacral region)	0.000	0.997	0.003
M49.06 Tuberculosis of spine (Lumbar region)	0.000	0.997	0.003
M49.05 Tuberculosis of spine (Thoracolumbar region)	0.000	0.997	0.003
M49.04 Tuberculosis of spine (Thoracic region)	0.000	0.997	0.003
M49.03 Tuberculosis of spine (Cervicothoracic region)	0.000	0.997	0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations