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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1027643
log Bayes Factor = 0.313074
Chromosome 5   position 91,893,792  (GRCh37) Explore rs1027643 on Ensembl!
Variant rs1027643 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M05-M14 Inflammatory polyarthropathies
0.515 0.485 0.000
M10.99 Gout, unspecified (Site unspecified)
0.514 0.486 0.000
M10.9 Gout, unspecified
0.514 0.486 0.000
M10 Gout
0.513 0.487 0.000
M20-M25 Other joint disorders
0.512 0.488 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.511 0.489 0.000
M23 Internal derangement of knee
0.500 0.500 0.000
M23.3 Other meniscus derangements
0.495 0.505 0.000
M80-M85 Disorders of bone density and structure
0.486 0.514 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.484 0.516 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.471 0.529 0.000
M22 Disorders of patella
0.470 0.530 0.000
M81 Osteoporosis without pathological fracture
0.466 0.534 0.000
M65-M68 Disorders of synovium and tendon
0.466 0.534 0.000
M07 Psoriatic and enteropathic arthropathies
0.461 0.539 0.000
M81.9 Osteoporosis, unspecified
0.452 0.548 0.000
M23.8 Other internal derangements of knee
0.448 0.552 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.443 0.557 0.000
M65 Synovitis and tenosynovitis
0.441 0.559 0.000
M22.4 Chondromalacia patellae
0.430 0.570 0.000
M06 Other rheumatoid arthritis
0.427 0.573 0.000
M31 Other necrotising vasculopathies
0.426 0.573 0.000
M07.3 Other psoriatic arthropathies
0.423 0.577 0.000
M86-M90 Other osteopathies
0.420 0.580 0.000
M21 Other acquired deformities of limbs
0.412 0.588 0.000
M91-M94 Chondropathies
0.410 0.589 0.000
M60-M63 Disorders of muscles
0.409 0.591 0.000
M24 Other specific joint derangements
0.403 0.597 0.000
M70-M79 Other soft tissue disorders
0.397 0.603 0.000
M65.3 Trigger finger
0.396 0.604 0.000
M33 Dermatopolymyositis
0.392 0.608 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.391 0.608 0.000
M10.94 Gout, unspecified (Hand)
0.391 0.609 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.391 0.609 0.000
M35 Other systemic involvement of connective tissue
0.388 0.612 0.000
M14 Arthropathies in other diseases classified elsewhere
0.388 0.612 0.000
M10.96 Gout, unspecified (Lower leg)
0.383 0.617 0.000
M23.0 Cystic meniscus
0.382 0.618 0.000
M31.6 Other giant cell arteritis
0.381 0.619 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.379 0.620 0.000
M25 Other joint disorders, not elsewhere classified
0.379 0.621 0.000
M22.2 Patellofemoral disorders
0.378 0.622 0.000
M23.9 Internal derangement of knee, unspecified
0.378 0.622 0.000
M84 Disorders of continuity of bone
0.377 0.623 0.000
M11 Other crystal arthropathies
0.376 0.624 0.000
M06.9 Rheumatoid arthritis, unspecified
0.376 0.624 0.000
M00-M03 Infectious arthropathies
0.374 0.626 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.374 0.626 0.000
M12 Other specific arthropathies
0.369 0.631 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.369 0.631 0.000
M08 Juvenile arthritis
0.369 0.631 0.000
M10.98 Gout, unspecified (Other)
0.369 0.631 0.000
M10.95 Gout, unspecified (Pelvic region and thigh)
0.369 0.631 0.000
M10.93 Gout, unspecified (Forearm)
0.369 0.631 0.000
M10.92 Gout, unspecified (Upper arm)
0.369 0.631 0.000
M10.91 Gout, unspecified (Shoulder region)
0.369 0.631 0.000
M10.90 Gout, unspecified (Multiple sites)
0.369 0.631 0.000
M10.4 Other secondary gout
0.368 0.632 0.000
M10.3 Gout due to impairment of renal function
0.368 0.632 0.000
M10.2 Drug-induced gout
0.368 0.632 0.000
M10.1 Lead-induced gout
0.368 0.632 0.000
M10.0 Idiopathic gout
0.368 0.632 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.367 0.633 0.000
M32 Systemic lupus erythematosus
0.367 0.633 0.000
M30 Polyarteritis nodosa and related conditions
0.367 0.633 0.000
M82 Osteoporosis in diseases classified elsewhere
0.366 0.634 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.366 0.634 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.365 0.635 0.000
M65.34 Trigger finger-Hand
0.364 0.636 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.359 0.641 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.359 0.641 0.000
M23.1 Discoid meniscus (congenital)
0.359 0.641 0.000
M23.37 Other meniscus derangements-Capsular lig
0.355 0.645 0.000
M21.0 Valgus deformity, not elsewhere classified
0.352 0.648 0.000
M83 Adult osteomalacia
0.349 0.651 0.000
M05 Seropositive rheumatoid arthritis
0.347 0.652 0.000
M65.8 Other synovitis and tenosynovitis
0.347 0.653 0.000
M34 Systemic sclerosis
0.346 0.654 0.000
M81.2 Osteoporosis of disuse
0.346 0.654 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.344 0.656 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.344 0.656 0.000
M81.98 Osteoporosis, unspecified (Other)
0.342 0.658 0.000
M66 Spontaneous rupture of synovium and tendon
0.342 0.658 0.000
M06.4 Inflammatory polyarthropathy
0.341 0.659 0.000
M85 Other disorders of bone density and structure
0.341 0.659 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.340 0.660 0.000
M22.1 Recurrent subluxation of patella
0.337 0.662 0.000
M22.9 Disorder of patella, unspecified
0.337 0.662 0.000
M22.3 Other derangements of patella
0.337 0.662 0.000
M22.0 Recurrent dislocation of patella
0.337 0.662 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.337 0.663 0.000
M24.2 Disorder of ligament
0.336 0.663 0.000
M62 Other disorders of muscle
0.336 0.664 0.000
M81.8 Other osteoporosis
0.334 0.665 0.000
M81.6 Localised osteoporosis [Lequesne]
0.334 0.665 0.000
M81.5 Idiopathic osteoporosis
0.334 0.665 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.334 0.665 0.000
M81.1 Postoophorectomy osteoporosis
0.334 0.665 0.000
M81.0 Postmenopausal osteoporosis
0.334 0.665 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.334 0.666 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.331 0.668 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.331 0.669 0.000
M07.6 Other enteropathic arthropathies
0.331 0.669 0.000
M07.5 Arthropathy in ulcerative colitis
0.331 0.669 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.331 0.669 0.000
M07.2 Psoriatic spondylitis
0.331 0.669 0.000
M07.1 Arthritis mutilans
0.331 0.669 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.331 0.669 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.330 0.670 0.000
M93 Other osteochondropathies
0.329 0.670 0.000
M22.8 Other disorders of patella
0.329 0.671 0.000
M79.0 Rheumatism, unspecified
0.328 0.672 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.328 0.672 0.000
M89 Other disorders of bone
0.327 0.673 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.327 0.673 0.000
M81.4 Drug-induced osteoporosis
0.327 0.673 0.000
M23.4 Loose body in knee
0.325 0.675 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.324 0.676 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.324 0.676 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.324 0.676 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.324 0.676 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.324 0.676 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.324 0.676 0.000
M80 Osteoporosis with pathological fracture
0.323 0.676 0.000
M23.87 Other internal derangements of knee (Capsular ligament)
0.321 0.679 0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.321 0.679 0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)
0.321 0.679 0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.321 0.679 0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.321 0.679 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.321 0.679 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.321 0.679 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.321 0.679 0.000
M21.2 Flexion deformity
0.319 0.681 0.000
M88 Paget's disease of bone [osteitis deformans]
0.318 0.682 0.000
M86 Osteomyelitis
0.318 0.682 0.000
M25.3 Other instability of joint
0.318 0.682 0.000
M40-M43 Deforming dorsopathies
0.316 0.684 0.000
M65.2 Calcific tendinitis
0.316 0.684 0.000
M65.1 Other infective (teno)synovitis
0.316 0.684 0.000
M65.0 Abscess of tendon sheath
0.316 0.684 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.314 0.686 0.000
M71 Other bursopathies
0.314 0.686 0.000
M87 Osteonecrosis
0.313 0.687 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.313 0.687 0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)
0.312 0.688 0.000
M35.1 Other overlap syndromes
0.311 0.689 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.311 0.689 0.000
M23.5 Chronic instability of knee
0.310 0.690 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.309 0.691 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.309 0.691 0.000
M94 Other disorders of cartilage
0.307 0.693 0.000
M33.1 Other dermatomyositis
0.306 0.693 0.000
M06.8 Other specified rheumatoid arthritis
0.306 0.694 0.000
M06.2 Rheumatoid bursitis
0.306 0.694 0.000
M06.1 Adult-onset Still's disease
0.306 0.694 0.000
M31.9 Necrotising vasculopathy, unspecified
0.306 0.694 0.000
M31.8 Other specified necrotising vasculopathies
0.306 0.694 0.000
M31.7 Microscopic polyangiitis
0.306 0.694 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.306 0.694 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.306 0.694 0.000
M31.2 Lethal midline granuloma
0.306 0.694 0.000
M31.1 Thrombotic microangiopathy
0.306 0.694 0.000
M31.0 Hypersensitivity angiitis
0.306 0.694 0.000
M06.3 Rheumatoid nodule
0.305 0.694 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.305 0.695 0.000
M25.8 Other specified joint disorders
0.304 0.696 0.000
M07.38 Other psoriatic arthropathies (Other)
0.303 0.696 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.303 0.696 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.303 0.696 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.303 0.696 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.303 0.696 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.303 0.696 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.303 0.696 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.303 0.696 0.000
M79.2 Neuralgia and neuritis, unspecified
0.299 0.701 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.298 0.702 0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)
0.298 0.702 0.000
M14.6 Neuropathic arthropathy
0.297 0.703 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.297 0.703 0.000
M70.6 Trochanteric bursitis
0.297 0.703 0.000
M25.4 Effusion of joint
0.297 0.703 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.296 0.704 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.296 0.704 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.296 0.704 0.000
M21.9 Acquired deformity of limb, unspecified
0.295 0.705 0.000
M21.8 Other specified acquired deformities of limbs
0.295 0.705 0.000
M21.7 Unequal limb length (acquired)
0.295 0.705 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.295 0.705 0.000
M21.4 Flat foot [pes planus] (acquired)
0.295 0.705 0.000
M92 Other juvenile osteochondrosis
0.294 0.705 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.294 0.705 0.000
M90 Osteopathies in diseases classified elsewhere
0.294 0.706 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.293 0.707 0.000
M61 Calcification and ossification of muscle
0.293 0.707 0.000
M60 Myositis
0.293 0.707 0.000
M21.1 Varus deformity, not elsewhere classified
0.292 0.708 0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)
0.290 0.710 0.000
M67 Other disorders of synovium and tendon
0.289 0.710 0.000
M24.9 Joint derangement, unspecified
0.289 0.711 0.000
M24.7 Protrusio acetabuli
0.289 0.711 0.000
M24.6 Ankylosis of joint
0.289 0.711 0.000
M24.5 Contracture of joint
0.289 0.711 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.289 0.711 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.287 0.713 0.000
M77 Other enthesopathies
0.285 0.714 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.285 0.715 0.000
M65.39 Trigger finger-Site unspec
0.284 0.716 0.000
M65.38 Trigger finger-Other
0.284 0.716 0.000
M65.37 Trigger finger-Ankle/foot
0.284 0.716 0.000
M65.36 Trigger finger-Lower leg
0.284 0.716 0.000
M65.35 Trigger finger-Pelvic/thigh
0.284 0.716 0.000
M65.33 Trigger finger-Forearm
0.284 0.716 0.000
M65.32 Trigger finger-Upper arm
0.284 0.716 0.000
M65.31 Trigger finger-Shldr region
0.284 0.716 0.000
M65.30 Trigger finger-Mult sites
0.284 0.716 0.000
M62.8 Other specified disorders of muscle
0.283 0.716 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.282 0.718 0.000
M24.24 Disorder of ligament (Hand)
0.282 0.718 0.000
M25.9 Joint disorder, unspecified
0.282 0.718 0.000
M76 Enthesopathies of lower limb, excluding foot
0.282 0.718 0.000
M33.9 Dermatopolymyositis, unspecified
0.281 0.719 0.000
M33.2 Polymyositis
0.281 0.719 0.000
M33.0 Juvenile dermatomyositis
0.281 0.719 0.000
M35.0 Sicca syndrome [Sjogren]
0.280 0.720 0.000
M82.1 Osteoporosis in endocrine disorders
0.280 0.720 0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)
0.280 0.720 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.280 0.720 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.279 0.721 0.000
M35.8 Other specified systemic involvement of connective tissue
0.279 0.721 0.000
M35.7 Hypermobility syndrome
0.279 0.721 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.279 0.721 0.000
M35.5 Multifocal fibrosclerosis
0.279 0.721 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.279 0.721 0.000
M35.2 Behcet's disease
0.279 0.721 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.278 0.722 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.278 0.722 0.000
M14.4 Arthropathy in amyloidosis
0.278 0.722 0.000
M14.3 Lipoid dermatoarthritis
0.278 0.722 0.000
M14.2 Diabetic arthropathy
0.278 0.722 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.278 0.722 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.278 0.722 0.000
M11.2 Other chondrocalcinosis
0.277 0.723 0.000
M00 Pyogenic arthritis
0.276 0.724 0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)
0.274 0.726 0.000
M23.07 Cystic meniscus-Capsular lig
0.274 0.726 0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)
0.274 0.726 0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.274 0.726 0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)
0.274 0.726 0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.274 0.726 0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.274 0.726 0.000
M23.00 Cystic meniscus (Multiple sites)
0.274 0.726 0.000
M79.1 Myalgia
0.273 0.727 0.000
M25.37 Other instability of joint (Ankle and foot)
0.273 0.727 0.000
M21.6 Other acquired deformities of ankle and foot
0.272 0.728 0.000
M84.0 Malunion of fracture
0.272 0.728 0.000
M25.2 Flail joint
0.272 0.728 0.000
M25.1 Fistula of joint
0.272 0.728 0.000
M13 Other arthritis
0.272 0.728 0.000
M93.9 Osteochondropathy, unspecified
0.271 0.728 0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)
0.271 0.729 0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)
0.271 0.729 0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)
0.271 0.729 0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.271 0.729 0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)
0.271 0.729 0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.271 0.729 0.000
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.271 0.729 0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)
0.271 0.729 0.000
M84.9 Disorder of continuity of bone, unspecified
0.270 0.730 0.000
M84.8 Other disorders of continuity of bone
0.270 0.730 0.000
M84.4 Pathological fracture, not elsewhere classified
0.270 0.730 0.000
M84.3 Stress fracture, not elsewhere classified
0.270 0.730 0.000
M84.2 Delayed union of fracture
0.270 0.730 0.000
M11.9 Crystal arthropathy, unspecified
0.270 0.730 0.000
M11.8 Other specified crystal arthropathies
0.270 0.730 0.000
M11.1 Familial chondrocalcinosis
0.270 0.730 0.000
M11.0 Hydroxyapatite deposition disease
0.270 0.730 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.270 0.730 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.270 0.730 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.270 0.730 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.268 0.732 0.000
M02 Reactive arthropathies
0.268 0.732 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.268 0.732 0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.268 0.732 0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.268 0.732 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.268 0.732 0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.268 0.732 0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.268 0.732 0.000
M21.3 Wrist or foot drop (acquired)
0.268 0.732 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.267 0.733 0.000
M25.0 Haemarthrosis
0.267 0.733 0.000
M79.7 Fibromyalgia
0.265 0.735 0.000
M08.9 Juvenile arthritis, unspecified
0.265 0.735 0.000
M08.8 Other juvenile arthritis
0.265 0.735 0.000
M08.4 Pauciarticular juvenile arthritis
0.265 0.735 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.265 0.735 0.000
M08.2 Juvenile arthritis with systemic onset
0.265 0.735 0.000
M08.1 Juvenile ankylosing spondylitis
0.265 0.735 0.000
M08.0 Juvenile rheumatoid arthritis
0.265 0.735 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.265 0.735 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.265 0.735 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.265 0.735 0.000
M09.0 Juvenile arthritis in psoriasis
0.265 0.735 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.265 0.735 0.000
M12.5 Traumatic arthropathy
0.265 0.735 0.000
M12.4 Intermittent hydrarthrosis
0.265 0.735 0.000
M12.3 Palindromic rheumatism
0.265 0.735 0.000
M12.2 Villonodular synovitis (pigmented)
0.265 0.735 0.000
M12.1 Kaschin-Beck disease
0.265 0.735 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.265 0.735 0.000
M10.09 Idiopathic gout (Site unspecified)
0.264 0.736 0.000
M10.08 Idiopathic gout (Other)
0.264 0.736 0.000
M10.07 Idiopathic gout (Ankle and foot)
0.264 0.736 0.000
M10.06 Idiopathic gout (Lower leg)
0.264 0.736 0.000
M10.05 Idiopathic gout (Pelvic region and thigh)
0.264 0.736 0.000
M10.04 Idiopathic gout (Hand)
0.264 0.736 0.000
M10.03 Idiopathic gout (Forearm)
0.264 0.736 0.000
M10.02 Idiopathic gout (Upper arm)
0.264 0.736 0.000
M10.01 Idiopathic gout (Shoulder region)
0.264 0.736 0.000
M10.00 Idiopathic gout (Multiple sites)
0.264 0.736 0.000
M10.19 Lead-induced gout (Site unspecified)
0.264 0.736 0.000
M10.18 Lead-induced gout (Other)
0.264 0.736 0.000
M10.17 Lead-induced gout (Ankle and foot)
0.264 0.736 0.000
M10.16 Lead-induced gout (Lower leg)
0.264 0.736 0.000
M10.15 Lead-induced gout (Pelvic region and thigh)
0.264 0.736 0.000
M10.14 Lead-induced gout (Hand)
0.264 0.736 0.000
M10.13 Lead-induced gout (Forearm)
0.264 0.736 0.000
M10.12 Lead-induced gout (Upper arm)
0.264 0.736 0.000
M10.11 Lead-induced gout (Shoulder region)
0.264 0.736 0.000
M10.10 Lead-induced gout (Multiple sites)
0.264 0.736 0.000
M10.29 Drug-induced gout (Site unspecified)
0.264 0.736 0.000
M10.28 Drug-induced gout (Other)
0.264 0.736 0.000
M10.27 Drug-induced gout (Ankle and foot)
0.264 0.736 0.000
M10.26 Drug-induced gout (Lower leg)
0.264 0.736 0.000
M10.25 Drug-induced gout (Pelvic region and thigh)
0.264 0.736 0.000
M10.24 Drug-induced gout (Hand)
0.264 0.736 0.000
M10.23 Drug-induced gout (Forearm)
0.264 0.736 0.000
M10.22 Drug-induced gout (Upper arm)
0.264 0.736 0.000
M10.21 Drug-induced gout (Shoulder region)
0.264 0.736 0.000
M10.20 Drug-induced gout (Multiple sites)
0.264 0.736 0.000
M10.39 Gout due to impairment of renal function (Site unspecified)
0.264 0.736 0.000
M10.38 Gout due to impairment of renal function (Other)
0.264 0.736 0.000
M10.37 Gout due to impairment of renal function (Ankle and foot)
0.264 0.736 0.000
M10.36 Gout due to impairment of renal function (Lower leg)
0.264 0.736 0.000
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)
0.264 0.736 0.000
M10.34 Gout due to impairment of renal function (Hand)
0.264 0.736 0.000
M10.33 Gout due to impairment of renal function (Forearm)
0.264 0.736 0.000
M10.32 Gout due to impairment of renal function (Upper arm)
0.264 0.736 0.000
M10.31 Gout due to impairment of renal function (Shoulder region)
0.264 0.736 0.000
M10.30 Gout due to impairment of renal function (Multiple sites)
0.264 0.736 0.000
M10.49 Other secondary gout (Site unspecified)
0.264 0.736 0.000
M10.48 Other secondary gout (Other)
0.264 0.736 0.000
M10.47 Other secondary gout (Ankle and foot)
0.264 0.736 0.000
M10.46 Other secondary gout (Lower leg)
0.264 0.736 0.000
M10.45 Other secondary gout (Pelvic region and thigh)
0.264 0.736 0.000
M10.44 Other secondary gout (Hand)
0.264 0.736 0.000
M10.43 Other secondary gout (Forearm)
0.264 0.736 0.000
M10.42 Other secondary gout (Upper arm)
0.264 0.736 0.000
M10.41 Other secondary gout (Shoulder region)
0.264 0.736 0.000
M10.40 Other secondary gout (Multiple sites)
0.264 0.736 0.000
M30.8 Other conditions related to polyarteritis nodosa
0.263 0.737 0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.263 0.737 0.000
M30.2 Juvenile polyarteritis
0.263 0.737 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.263 0.737 0.000
M30.0 Polyarteritis nodosa
0.263 0.737 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.263 0.737 0.000
M32.8 Other forms of systemic lupus erythematosus
0.263 0.737 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.263 0.737 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.263 0.737 0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.263 0.737 0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.263 0.737 0.000
M36.3 Arthropathy in other blood disorders
0.263 0.737 0.000
M36.2 Haemophilic arthropathy
0.263 0.737 0.000
M36.1 Arthropathy in neoplastic disease
0.263 0.737 0.000
M36.0 Dermato(poly)myositis in neoplastic disease
0.263 0.737 0.000
M31.3 Wegener's granulomatosis
0.263 0.737 0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh
0.263 0.737 0.000
M82.8 Osteoporosis in other diseases classified elsewhere
0.262 0.737 0.000
M82.0 Osteoporosis in multiple myelomatosis
0.262 0.737 0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm
0.262 0.737 0.000
M35.3 Polymyalgia rheumatica
0.261 0.739 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.259 0.740 0.000
M81.20 Osteoporosis of disuse (Multiple sites)
0.259 0.741 0.000
M79.08 Rheumatism, unspecified (Other)
0.259 0.741 0.000
M70.4 Prepatellar bursitis
0.259 0.741 0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)
0.257 0.742 0.000
M23.17 Discoid meniscus (congenital)-Capsular lig
0.257 0.742 0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)
0.257 0.742 0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)
0.257 0.742 0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.257 0.742 0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)
0.257 0.742 0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.257 0.742 0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.257 0.742 0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)
0.257 0.742 0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)
0.257 0.742 0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)
0.257 0.742 0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp
0.257 0.742 0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn
0.257 0.742 0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.257 0.742 0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.257 0.742 0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.257 0.742 0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.257 0.742 0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)
0.257 0.742 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.257 0.743 0.000
M24.0 Loose body in joint
0.255 0.745 0.000
M70.2 Olecranon bursitis
0.255 0.745 0.000
M25.86 Other specified joint disorders (Lower leg)
0.255 0.745 0.000
M21.27 Flexion deformity (Ankle and foot)
0.254 0.746 0.000
M66.0 Rupture of popliteal cyst
0.253 0.746 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.253 0.747 0.000
M89.5 Osteolysis
0.253 0.747 0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)
0.252 0.747 0.000
M21.08 Valgus deformity, not elsewhere classified (Other)
0.252 0.747 0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)
0.252 0.747 0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)
0.252 0.747 0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)
0.252 0.747 0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)
0.252 0.747 0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)
0.252 0.747 0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)
0.252 0.747 0.000
M34.1 CR(E)ST syndrome
0.252 0.748 0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)
0.251 0.749 0.000
M89.8 Other specified disorders of bone
0.251 0.749 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.250 0.749 0.000
M83.9 Adult osteomalacia, unspecified
0.250 0.750 0.000
M83.8 Other adult osteomalacia
0.250 0.750 0.000
M83.5 Other drug-induced osteomalacia in adults
0.250 0.750 0.000
M83.4 Aluminum bone disease
0.250 0.750 0.000
M83.3 Adult osteomalacia due to malnutrition
0.250 0.750 0.000
M83.2 Adult osteomalacia due to malabsorption
0.250 0.750 0.000
M83.1 Senile osteomalacia
0.250 0.750 0.000
M83.0 Puerperal osteomalacia
0.250 0.750 0.000
M05.8 Other seropositive rheumatoid arthritis
0.249 0.751 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.249 0.751 0.000
M05.2 Rheumatoid vasculitis
0.249 0.751 0.000
M05.1 Rheumatoid lung disease
0.249 0.751 0.000
M05.0 Felty's syndrome
0.249 0.751 0.000
M65.89 Other synovitis and tenosynovitis (Site unspecified)
0.249 0.751 0.000
M65.88 Other synovitis and tenosynovitis (Other)
0.249 0.751 0.000
M65.87 Other synovitis and tenosynovitis (Ankle and foot)
0.249 0.751 0.000
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)
0.249 0.751 0.000
M65.84 Other synovitis and tenosynovitis (Hand)
0.249 0.751 0.000
M65.83 Other synovitis and tenosynovitis (Forearm)
0.249 0.751 0.000
M65.82 Other synovitis and tenosynovitis (Upper arm)
0.249 0.751 0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)
0.249 0.751 0.000
M65.80 Other synovitis and tenosynovitis (Multiple sites)
0.249 0.751 0.000
M34.8 Other forms of systemic sclerosis
0.248 0.751 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.248 0.751 0.000
M34.0 Progressive systemic sclerosis
0.248 0.751 0.000
M81.29 Osteoporosis of disuse (Site unspecified)
0.248 0.752 0.000
M81.28 Osteoporosis of disuse (Other)
0.248 0.752 0.000
M81.27 Osteoporosis of disuse (Ankle and foot)
0.248 0.752 0.000
M81.26 Osteoporosis of disuse (Lower leg)
0.248 0.752 0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)
0.248 0.752 0.000
M81.24 Osteoporosis of disuse (Hand)
0.248 0.752 0.000
M81.23 Osteoporosis of disuse (Forearm)
0.248 0.752 0.000
M81.22 Osteoporosis of disuse (Upper arm)
0.248 0.752 0.000
M81.21 Osteoporosis of disuse (Shoulder region)
0.248 0.752 0.000
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure
0.247 0.753 0.000
M70.8 Other soft tissue disorders related to use, overuse and pressure
0.247 0.753 0.000
M70.7 Other bursitis of hip
0.247 0.753 0.000
M70.5 Other bursitis of knee
0.247 0.753 0.000
M70.3 Other bursitis of elbow
0.247 0.753 0.000
M70.1 Bursitis of hand
0.247 0.753 0.000
M70.0 Chronic crepitant synovitis of hand and wrist
0.247 0.753 0.000
M79.9 Soft tissue disorder, unspecified
0.247 0.753 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.247 0.753 0.000
M79.3 Panniculitis, unspecified
0.247 0.753 0.000
M87.2 Osteonecrosis due to previous trauma
0.247 0.753 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.246 0.754 0.000
M88.9 Paget's disease of bone, unspecified
0.246 0.754 0.000
M86.9 Osteomyelitis, unspecified
0.246 0.754 0.000
M66.5 Spontaneous rupture of unspecified tendon
0.245 0.754 0.000
M66.4 Spontaneous rupture of other tendons
0.245 0.754 0.000
M66.3 Spontaneous rupture of flexor tendons
0.245 0.754 0.000
M66.1 Rupture of synovium
0.245 0.754 0.000
M66.2 Spontaneous rupture of extensor tendons
0.245 0.755 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.245 0.755 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.245 0.755 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.245 0.755 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.245 0.755 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.245 0.755 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.245 0.755 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.245 0.755 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.245 0.755 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.245 0.755 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.245 0.755 0.000
M85.9 Disorder of bone density and structure, unspecified
0.244 0.756 0.000
M85.6 Other cyst of bone
0.244 0.756 0.000
M85.5 Aneurysmal bone cyst
0.244 0.756 0.000
M85.4 Solitary bone cyst
0.244 0.756 0.000
M85.3 Osteitis condensans
0.244 0.756 0.000
M85.2 Hyperostosis of skull
0.244 0.756 0.000
M85.1 Skeletal fluorosis
0.244 0.756 0.000
M85.0 Fibrous dysplasia (monostotic)
0.244 0.756 0.000
M71.1 Other infective bursitis
0.244 0.756 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.244 0.756 0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.243 0.757 0.000
M22.10 Recurrent subluxation of patella, unspecified knee
0.242 0.758 0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)
0.242 0.758 0.000
M24.29 Disorder of ligament (Site unspecified)
0.241 0.758 0.000
M24.28 Disorder of ligament (Other)
0.241 0.758 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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