TreeWAS – Variant ID: rs1031391

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D25.1 Intramural leiomyoma of uterus	0.000	0.796	0.204
D86.9 Sarcoidosis, unspecified	0.000	0.878	0.122
D86 Sarcoidosis	0.000	0.889	0.111
D86.0 Sarcoidosis of lung	0.000	0.898	0.102
D80-D89 Certain disorders involving the immune mechanism	0.000	0.905	0.095
D86.3 Sarcoidosis of skin	0.000	0.909	0.090
D80 Immunodeficiency with predominantly antibody defects	0.000	0.911	0.089
K51 Ulcerative colitis	0.088	0.912	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.087	0.913	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.000	0.916	0.084
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.916	0.084
D84 Other immunodeficiencies	0.000	0.918	0.082
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.919	0.081
K51.4 Pseudopolyposis of colon	0.079	0.921	0.000
K51.2 Ulcerative (chronic) proctitis	0.079	0.921	0.000
D83 Common variable immunodeficiency	0.000	0.925	0.075
K51.8 Other ulcerative colitis	0.075	0.925	0.000
K51.9 Ulcerative colitis, unspecified	0.074	0.926	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.926	0.074
K51.0 Ulcerative (chronic) enterocolitis	0.072	0.928	0.000
D86.8 Sarcoidosis of other and combined sites	0.000	0.929	0.071
D81 Combined immunodeficiencies	0.000	0.932	0.068
D84.9 Immunodeficiency, unspecified	0.000	0.932	0.067
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.935	0.065
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.935	0.065
D84.1 Defects in the complement system	0.000	0.935	0.065
D84.8 Other specified immunodeficiencies	0.000	0.936	0.064
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.936	0.064
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.936	0.064
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.936	0.064
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.936	0.064
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.936	0.064
K51.1 Ulcerative (chronic) ileocolitis	0.064	0.936	0.000
D82 Immunodeficiency associated with other major defects	0.000	0.937	0.063
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.938	0.062
D83.9 Common variable immunodeficiency, unspecified	0.000	0.938	0.061
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.941	0.059
K50-K52 Noninfective enteritis and colitis	0.058	0.942	0.000
K50 Crohn's disease [regional enteritis]	0.057	0.943	0.000
K50.1 Crohn's disease of large intestine	0.056	0.944	0.000
K50.8 Other Crohn's disease	0.056	0.944	0.000
D86.1 Sarcoidosis of lymph nodes	0.000	0.945	0.054
D83.8 Other common variable immunodeficiencies	0.000	0.946	0.054
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.946	0.054
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.946	0.054
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.946	0.054
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.947	0.053
K51.5 Mucosal proctocolitis	0.050	0.949	0.000
D81.9 Combined immunodeficiency, unspecified	0.000	0.951	0.049
D81.8 Other combined immunodeficiencies	0.000	0.951	0.049
D81.7 Major histocompatibility complex class II deficiency	0.000	0.951	0.049
D81.6 Major histocompatibility complex class I deficiency	0.000	0.951	0.049
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.951	0.049
D81.4 Nezelof's syndrome	0.000	0.951	0.049
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.951	0.049
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.951	0.049
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.951	0.049
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.951	0.049
I45.1 Other and unspecified right bundle-branch block	0.000	0.952	0.048
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.954	0.046
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.955	0.045
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.955	0.045
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.955	0.045
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.955	0.045
D82.2 Immunodeficiency with short-limbed stature	0.000	0.955	0.045
D82.0 Wiskott-Aldrich syndrome	0.000	0.955	0.045
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.955	0.045
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.955	0.045
D89.3 Immune reconstitution syndrome	0.000	0.955	0.044
D89.1 Cryoglobulinaemia	0.000	0.958	0.041
M25.78 Osteophyte (Other)	0.000	0.960	0.040
D82.1 Di George's syndrome	0.000	0.960	0.040
D25 Leiomyoma of uterus	0.000	0.960	0.040
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.962	0.038
K50.0 Crohn's disease of small intestine	0.037	0.963	0.000
D25.0 Submucous leiomyoma of uterus	0.000	0.964	0.036
E83.4 Disorders of magnesium metabolism	0.030	0.970	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.022	0.978	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.019	0.981	0.000
D68.2 Hereditary deficiency of other clotting factors	0.018	0.982	0.000
D25.2 Subserosal leiomyoma of uterus	0.000	0.982	0.018
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.017	0.983	0.000
Z63 Other problems related to primary support group, including family circumstances	0.015	0.985	0.000
N99.0 Postprocedural renal failure	0.015	0.985	0.000
Z58 Problems related to physical environment	0.014	0.986	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.014	0.986	0.000
Z63.7 Other stressful life events affecting family and household	0.014	0.986	0.000
Z58.8 Other problems related to physical environment	0.014	0.986	0.000
N99.1 Postprocedural urethral stricture	0.013	0.986	0.000
Z63.5 Disruption of family by separation and divorce	0.013	0.987	0.000
Z63.0 Problems in relationship with spouse or partner	0.013	0.987	0.000
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.013	0.987	0.000
D68 Other coagulation defects	0.013	0.987	0.000
Z60 Problems related to social environment	0.012	0.988	0.000
Z59 Problems related to housing and economic circumstances	0.012	0.988	0.000
Z63.4 Disappearance and death of family member	0.012	0.988	0.000
D68.8 Other specified coagulation defects	0.012	0.988	0.000
Z63.8 Other specified problems related to primary support group	0.012	0.988	0.000
Z56 Problems related to employment and unemployment	0.012	0.988	0.000
D68.5 Primary Thrombophilia	0.012	0.988	0.000
Z60.2 Living alone	0.011	0.989	0.000
Z58.7 Exposure to tobacco smoke	0.011	0.989	0.000
Z63.9 Problem related to primary support group, unspecified	0.011	0.989	0.000
Z63.3 Absence of family member	0.011	0.989	0.000
Z63.2 Inadequate family support	0.011	0.989	0.000
Z63.1 Problems in relationship with parents and in-laws	0.011	0.989	0.000
Z58.1 Exposure to air pollution	0.011	0.989	0.000
Z58.5 Exposure to other pollution	0.011	0.989	0.000
Z61 Problems related to negative life events in childhood	0.011	0.989	0.000
Z63.6 Dependent relative needing care at home	0.011	0.989	0.000
M89.98 Disorder of bone, unspecified (Other)	0.011	0.989	0.000
K50.9 Crohn's disease, unspecified	0.011	0.989	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.011	0.989	0.000
D68.0 Von Willebrand's disease	0.011	0.989	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.000	0.989	0.011
Z58.9 Problem related to physical environment, unspecified	0.010	0.990	0.000
Z58.6 Inadequate drinking-water supply	0.010	0.990	0.000
Z58.4 Exposure to radiation	0.010	0.990	0.000
Z58.3 Exposure to soil pollution	0.010	0.990	0.000
Z58.2 Exposure to water pollution	0.010	0.990	0.000
Z58.0 Exposure to noise	0.010	0.990	0.000
M89.9 Disorder of bone, unspecified	0.010	0.990	0.000
Z59.1 Inadequate housing	0.010	0.990	0.000
Z62 Other problems related to upbringing	0.010	0.990	0.000
Z55 Problems related to education and literacy	0.010	0.990	0.000
Z60.8 Other problems related to social environment	0.010	0.990	0.000
Z65 Problems related to other psychosocial circumstances	0.010	0.990	0.000
N99.2 Postprocedural adhesions of vagina	0.010	0.990	0.000
Z56.6 Other physical and mental strain related to work	0.010	0.990	0.000
Z59.0 Homelessness	0.010	0.990	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.009	0.990	0.000
Z56.7 Other and unspecified problems related to employment	0.009	0.990	0.000
Z64 Problems related to certain psychosocial circumstances	0.009	0.991	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.009	0.991	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.009	0.991	0.000
D68.6 Other Thrombophilia	0.009	0.991	0.000
Z59.8 Other problems relating to housing and economic circumstances	0.009	0.991	0.000
Z60.5 Target of perceived adverse discrimination and persecution	0.009	0.991	0.000
Z60.4 Social exclusion and rejection	0.009	0.991	0.000
Z60.3 Acculturation difficulty	0.009	0.991	0.000
Z60.1 Atypical parenting situation	0.009	0.991	0.000
Z60.0 Problems of adjustment to life-cycle transitions	0.009	0.991	0.000
N99.5 Malfunction of external stoma of urinary tract	0.009	0.991	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.009	0.991	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.009	0.991	0.000
Z59.7 Insufficient social insurance and welfare support	0.009	0.991	0.000
Z59.6 Low income	0.009	0.991	0.000
Z59.5 Extreme poverty	0.009	0.991	0.000
Z59.4 Lack of adequate food	0.009	0.991	0.000
Z59.3 Problems related to living in residential institution	0.009	0.991	0.000
Z59.2 Discord with neighbours, lodgers and landlord	0.009	0.991	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.009	0.991	0.000
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.009	0.991	0.000
Z60.9 Problem related to social environment, unspecified	0.009	0.991	0.000
D68.4 Acquired coagulation factor deficiency	0.009	0.991	0.000
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.009	0.991	0.000
Z56.5 Uncongenial work	0.008	0.991	0.000
Z56.4 Discord with boss and workmates	0.008	0.991	0.000
Z56.2 Threat of job loss	0.008	0.991	0.000
Z56.1 Change of job	0.008	0.991	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.008	0.991	0.000
Z56.3 Stressful work schedule	0.008	0.992	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.992	0.008
Z61.6 Problems related to alleged physical abuse of child	0.008	0.992	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.008	0.992	0.000
Z61.8 Other negative life events in childhood	0.008	0.992	0.000
D68.1 Hereditary factor XI deficiency	0.008	0.992	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.008	0.992	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.008	0.992	0.000
Z61.9 Negative life events in childhood, unspecified	0.008	0.992	0.000
Z61.7 Personal frightening experience in childhood	0.008	0.992	0.000
Z61.3 Events resulting in loss of self-esteem in childhood	0.008	0.992	0.000
Z61.2 Altered pattern of family relationships in childhood	0.008	0.992	0.000
Z61.1 Removal from home in childhood	0.008	0.992	0.000
Z61.0 Loss of love relationship in childhood	0.008	0.992	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.008	0.992	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.008	0.992	0.000
K90.0 Coeliac disease	0.000	0.992	0.008
T50.4 Drugs affecting uric acid metabolism	0.008	0.992	0.000
Z56.0 Unemployment, unspecified	0.008	0.992	0.000
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.008	0.992	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.008	0.992	0.000
Z55.9 Problems relating to education and literacy, unspecified	0.007	0.992	0.000
Z55.8 Other problems relating to education and literacy	0.007	0.992	0.000
Z55.4 Educational maladjustment and discord with teachers and classmates	0.007	0.992	0.000
Z55.3 Underachievement in school	0.007	0.992	0.000
Z55.2 Failed examinations	0.007	0.992	0.000
Z55.1 Schooling unavailable and unattainable	0.007	0.992	0.000
Z55.0 Illiteracy and low-level literacy	0.007	0.992	0.000
Z62.9 Problem related to upbringing, unspecified	0.007	0.992	0.000
Z62.8 Other specified problems related to upbringing	0.007	0.992	0.000
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.007	0.992	0.000
Z62.5 Other problems related to neglect in upbringing	0.007	0.992	0.000
Z62.4 Emotional neglect of child	0.007	0.992	0.000
Z62.3 Hostility towards and scapegoating of child	0.007	0.992	0.000
Z62.2 Institutional upbringing	0.007	0.992	0.000
Z62.1 Parental overprotection	0.007	0.992	0.000
Z62.0 Inadequate parental supervision and control	0.007	0.992	0.000
I83 Varicose veins of lower extremities	0.000	0.992	0.008
M89.99 Disorder of bone, unspecified (Site unspecified)	0.007	0.992	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.008	0.992	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.007	0.992	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.007	0.992	0.000
N99-N99 Other disorders of the genitourinary system	0.007	0.993	0.000
Z65.9 Problem related to unspecified psychosocial circumstances	0.007	0.993	0.000
Z65.5 Exposure to disaster, war and other hostilities	0.007	0.993	0.000
Z65.4 Victim of crime and terrorism	0.007	0.993	0.000
Z65.3 Problems related to other legal circumstances	0.007	0.993	0.000
Z65.2 Problems related to release from prison	0.007	0.993	0.000
Z65.1 Imprisonment and other incarceration	0.007	0.993	0.000
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.007	0.993	0.000
M89 Other disorders of bone	0.007	0.993	0.000
Z64.4 Discord with counsellors	0.007	0.993	0.000
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.007	0.993	0.000
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.007	0.993	0.000
Z64.1 Problems related to multiparity	0.007	0.993	0.000
T46.1 Calcium-channel blockers	0.007	0.993	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.007	0.993	0.000
T46.7 Peripheral vasodilators	0.007	0.993	0.000
Y40.0 Penicillins	0.007	0.993	0.000
Z65.8 Other specified problems related to psychosocial circumstances	0.007	0.993	0.000
T50.8 Diagnostic agents	0.007	0.993	0.000
M89.8 Other specified disorders of bone	0.007	0.993	0.000
T50.1 Loop [high-ceiling] diuretics	0.007	0.993	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.007	0.993	0.000
T50.7 Analeptics and opioid receptor antagonists	0.007	0.993	0.000
T50.5 Appetite depressants	0.007	0.993	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.007	0.993	0.000
T50.0 Mineralocorticoids and their antagonists	0.007	0.993	0.000
M89.0 Algoneurodystrophy	0.007	0.993	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.006	0.994	0.000
T36 Poisoning by systemic antibiotics	0.006	0.994	0.000
Z64.0 Problems related to unwanted pregnancy	0.006	0.994	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.006	0.994	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.006	0.994	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.006	0.994	0.000
T36.0 Penicillins	0.006	0.994	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.006	0.994	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.006	0.994	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.006	0.994	0.000
M89.83 Other specified disorders of bone (Forearm)	0.006	0.994	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.005	0.994	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.005	0.994	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.000	0.994	0.005
M89.6 Osteopathy after poliomyelitis	0.005	0.994	0.000
M89.2 Other disorders of bone development and growth	0.005	0.994	0.000
M89.1 Epiphyseal arrest	0.005	0.994	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.005	0.995	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.005	0.995	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.005	0.995	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.005	0.995	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.005	0.995	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.005	0.995	0.000
M89.88 Other specified disorders of bone (Other)	0.005	0.995	0.000
M89.3 Hypertrophy of bone	0.005	0.995	0.000
T47.4 Other laxatives	0.005	0.995	0.000
M89.04 Algoneurodystrophy (Hand)	0.005	0.995	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.005	0.995	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.005	0.995	0.000
T47.2 Stimulant laxatives	0.005	0.995	0.000
T36.3 Macrolides	0.005	0.995	0.000
M89.03 Algoneurodystrophy (Forearm)	0.005	0.995	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.005	0.995	0.000
Z57 Occupational exposure to risk-factors	0.005	0.995	0.000
M89.08 Algoneurodystrophy (Other)	0.005	0.995	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.005	0.995	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.005	0.995	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.005	0.995	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.005	0.995	0.000
T47.6 Antidiarrhoeal drugs	0.005	0.995	0.000
T36.8 Other systemic antibiotics	0.005	0.995	0.000
K52 Other non-infective gastro-enteritis and colitis	0.005	0.995	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.005	0.995	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.005	0.995	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.005	0.995	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.005	0.995	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.000	0.995	0.005
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.005	0.995	0.000
T36.9 Systemic antibiotic, unspecified	0.005	0.995	0.000
T36.7 Antifungal antibiotics, systemically used	0.005	0.995	0.000
T36.6 Rifamycins	0.005	0.995	0.000
T36.5 Aminoglycosides	0.005	0.995	0.000
T36.2 Chloramphenicol group	0.005	0.995	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.005	0.995	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.005	0.995	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.005	0.995	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.005	0.995	0.000
I45 Other conduction disorders	0.000	0.995	0.005
N71.9 Inflammatory disease of uterus, unspecified	0.000	0.995	0.005
T38.0 Glucocorticoids and synthetic analogues	0.005	0.995	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.005	0.995	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.005	0.995	0.000
T47.7 Emetics	0.005	0.995	0.000
T47.5 Digestants	0.005	0.995	0.000
T47.3 Saline and osmotic laxatives	0.005	0.995	0.000
T47.0 Histamine H(2)-receptor antagonists	0.004	0.995	0.000
I45.9 Conduction disorder, unspecified	0.000	0.995	0.005
M89.84 Other specified disorders of bone (Hand)	0.004	0.995	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.004	0.995	0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.000	0.996	0.004
T38.1 Thyroid hormones and substitutes	0.004	0.996	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.004	0.996	0.000
M89.5 Osteolysis	0.004	0.996	0.000
T36.4 Tetracyclines	0.004	0.996	0.000
E10.4 With neurological complications	0.000	0.996	0.004
K52.0 Gastro-enteritis and colitis due to radiation	0.004	0.996	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.004	0.996	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.004	0.996	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.004	0.996	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.004	0.996	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.004	0.996	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.004	0.996	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.004	0.996	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.004	0.996	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.004	0.996	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.004	0.996	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.004	0.996	0.000
M89.38 Hypertrophy of bone (Other)	0.004	0.996	0.000
Z57.8 Occupational exposure to other risk-factors	0.004	0.996	0.000
M89.19 Epiphyseal arrest (Site unspecified)	0.004	0.996	0.000
M89.18 Epiphyseal arrest (Other)	0.004	0.996	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.004	0.996	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.004	0.996	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.004	0.996	0.000
M89.14 Epiphyseal arrest (Hand)	0.004	0.996	0.000
M89.13 Epiphyseal arrest (Forearm)	0.004	0.996	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.004	0.996	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.004	0.996	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.004	0.996	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.004	0.996	0.000
M89.28 Other disorders of bone development and growth (Other)	0.004	0.996	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.004	0.996	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.004	0.996	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.004	0.996	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.004	0.996	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.004	0.996	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.004	0.996	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.004	0.996	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.004	0.996	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.004	0.996	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.004	0.996	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.004	0.996	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.004	0.996	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.004	0.996	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.004	0.996	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.004	0.996	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.004	0.996	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.004	0.996	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.004	0.996	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.004	0.996	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.996	0.004
I45.6 Preexcitation syndrome	0.000	0.996	0.004
E10.1 With ketoacidosis	0.000	0.996	0.004
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.004	0.996	0.000
T38.5 Other oestrogens and progestogens	0.004	0.996	0.000
E10.0 With coma	0.000	0.996	0.004
I85.0 Oesophageal varices with bleeding	0.004	0.996	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.004	0.996	0.000
T38.9 Other and unspecified hormone antagonists	0.004	0.996	0.000
T38.7 Androgens and anabolic congeners	0.004	0.996	0.000
T38.4 Oral contraceptives	0.004	0.996	0.000
T38.2 Antithyroid drugs	0.004	0.996	0.000
D67 Hereditary factor IX deficiency	0.004	0.996	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.004	0.996	0.000
T48.4 Expectorants	0.004	0.996	0.000
T48.3 Antitussives	0.004	0.996	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.004	0.996	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.004	0.996	0.000
T48.0 Oxytocic drugs	0.004	0.996	0.000
M89.39 Hypertrophy of bone (Site unspecified)	0.004	0.996	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.004	0.996	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.004	0.996	0.000
M89.34 Hypertrophy of bone (Hand)	0.004	0.996	0.000
M89.33 Hypertrophy of bone (Forearm)	0.004	0.996	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.004	0.996	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.004	0.996	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.004	0.996	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.004	0.996	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.004	0.996	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.004	0.996	0.000
T37.5 Antiviral drugs	0.004	0.996	0.000
T37.4 Anthelminthics	0.004	0.996	0.000
T37.3 Other antiprotozoal drugs	0.004	0.996	0.000
T37.1 Antimycobacterial drugs	0.004	0.996	0.000
T37.0 Sulphonamides	0.004	0.996	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.004	0.996	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.004	0.996	0.000
Z57.7 Occupational exposure to vibration	0.004	0.996	0.000
Z57.6 Occupational exposure to extreme temperature	0.004	0.996	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.004	0.996	0.000
Z57.1 Occupational exposure to radiation	0.004	0.996	0.000
Z57.0 Occupational exposure to noise	0.004	0.996	0.000
N71 Inflammatory disease of uterus, except cervix	0.000	0.996	0.004
E10.6 With other specified complications	0.000	0.996	0.004
D68.9 Coagulation defect, unspecified	0.004	0.996	0.000
G93.4 Encephalopathy, unspecified	0.004	0.996	0.000
T41.5 Therapeutic gases	0.004	0.996	0.000
T41.4 Anaesthetic, unspecified	0.004	0.996	0.000
T41.3 Local anaesthetics	0.004	0.996	0.000
T41.2 Other and unspecified general anaesthetics	0.004	0.996	0.000
T41.1 Intravenous anaesthetics	0.004	0.996	0.000
T41.0 Inhaled anaesthetics	0.004	0.996	0.000
T49.9 Topical agent, unspecified	0.004	0.996	0.000
T49.8 Other topical agents	0.004	0.996	0.000
T49.7 Dental drugs, topically applied	0.004	0.996	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.004	0.996	0.000
T49.5 Ophthalmological drugs and preparations	0.004	0.996	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.004	0.996	0.000
T49.3 Emollients, demulcents and protectants	0.004	0.996	0.000
T49.2 Local astringents and local detergents	0.004	0.996	0.000
T49.1 Antipruritics	0.004	0.996	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.004	0.996	0.000
T42.1 Iminostilbenes	0.004	0.996	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.004	0.996	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.004	0.996	0.000
T48.5 Anti-common-cold drugs	0.003	0.996	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.004	0.996	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.996	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.996	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.996	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.996	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.003	0.996	0.000
T44.0 Anticholinesterase agents	0.003	0.996	0.000
N71.1 Chronic inflammatory disease of uterus	0.000	0.996	0.004
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.003	0.996	0.000
E10.8 With unspecified complications	0.000	0.996	0.004
E66.8 Other obesity	0.004	0.996	0.000
T42.0 Hydantoin derivatives	0.003	0.996	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.996	0.003
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.003	0.997	0.000
H43.1 Vitreous haemorrhage	0.000	0.997	0.003
M89.59 Osteolysis (Site unspecified)	0.003	0.997	0.000
M89.58 Osteolysis (Other)	0.003	0.997	0.000
M89.57 Osteolysis (Ankle and foot)	0.003	0.997	0.000
M89.56 Osteolysis (Lower leg)	0.003	0.997	0.000
M89.54 Osteolysis (Hand)	0.003	0.997	0.000
M89.53 Osteolysis (Forearm)	0.003	0.997	0.000
M89.52 Osteolysis (Upper arm)	0.003	0.997	0.000
M89.51 Osteolysis (Shoulder region)	0.003	0.997	0.000
M89.50 Osteolysis (Multiple sites)	0.003	0.997	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
L60.2 Onychogryphosis	0.003	0.997	0.000
D09.0 Bladder	0.003	0.997	0.000
T42.3 Barbiturates	0.003	0.997	0.000
E10.7 With multiple complications	0.000	0.997	0.003
E10.3 With ophthalmic complications	0.000	0.997	0.003
Z57.3 Occupational exposure to other air contaminants	0.003	0.997	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.003	0.997	0.000
T45.5 Anticoagulants	0.003	0.997	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.003	0.997	0.000
S80.8 Other superficial injuries of lower leg	0.000	0.997	0.003
T42.5 Mixed antiepileptics, not elsewhere classified	0.003	0.997	0.000
T42.2 Succinimides and oxazolidinediones	0.003	0.997	0.000
I45.0 Right fascicular block	0.000	0.997	0.003
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.003	0.997	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.003	0.997	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.003	0.997	0.000
I45.3 Trifascicular block	0.000	0.997	0.003
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.003	0.997	0.000
K70.1 Alcoholic hepatitis	0.003	0.997	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.003	0.997	0.000
D69 Purpura and other haemorrhagic conditions	0.003	0.997	0.000
M94.8 Other specified disorders of cartilage	0.000	0.997	0.003
K86.0 Alcohol-induced chronic pancreatitis	0.003	0.997	0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.000	0.997	0.003
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.000	0.997	0.003
E10.2 With renal complications	0.000	0.997	0.003
R25.2 Cramp and spasm	0.003	0.997	0.000
D48.5 Skin	0.003	0.997	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
Z01.6 Radiological examination, not elsewhere classified	0.000	0.997	0.003
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.003	0.997	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.003	0.997	0.000
K70.9 Alcoholic liver disease, unspecified	0.003	0.997	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.003	0.997	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.003	0.997	0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.000	0.997	0.003
T45.9 Primarily systemic and haematological agent, unspecified	0.002	0.997	0.000
T45.8 Other primarily systemic and haematological agents	0.002	0.997	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.997	0.000
T45.6 Fibrinolysis-affecting drugs	0.002	0.997	0.000
T45.4 Iron and its compounds	0.002	0.997	0.000
T45.3 Enzymes, not elsewhere classified	0.002	0.997	0.000
U51.1 Previously admitted to a psychiatric hospital of the provider	0.000	0.997	0.003
D66 Hereditary factor VIII deficiency	0.003	0.997	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.003	0.997	0.000
Q82.5 Congenital nonneoplastic naevus	0.000	0.997	0.003
N70-N77 Inflammatory diseases of female pelvic organs	0.000	0.997	0.003
D69.8 Other specified haemorrhagic conditions	0.003	0.997	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.003	0.997	0.000
K70 Alcoholic liver disease	0.003	0.997	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.003	0.997	0.000
N71.0 Acute inflammatory disease of uterus	0.000	0.997	0.003
M94.88 Other specified disorders of cartilage (Other)	0.000	0.997	0.003
E10.9 Without complications	0.000	0.997	0.003
N28.8 Other specified disorders of kidney and ureter	0.003	0.997	0.000
Y40 Systemic antibiotics	0.003	0.997	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.003	0.997	0.000
D69.1 Qualitative platelet defects	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations