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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10440708
log Bayes Factor = 1.90063
Chromosome 5   position 172,650,487  (GRCh37) Explore rs10440708 on Ensembl!
Variant rs10440708 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.987 0.013 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.984 0.016 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.982 0.018 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.974 0.026 0.000
R50-R69 General symptoms and signs
0.971 0.029 0.000
M20-M25 Other joint disorders
0.970 0.030 0.000
Chapter X Diseases of the respiratory system
0.969 0.031 0.000
R06 Abnormalities of breathing
0.959 0.041 0.000
R06.0 Dyspnoea
0.944 0.056 0.000
R63 Symptoms and signs concerning food and fluid intake
0.922 0.078 0.000
M20 Acquired deformities of fingers and toes
0.914 0.086 0.000
M15-M19 Arthrosis
0.893 0.107 0.000
R63.4 Abnormal weight loss
0.885 0.115 0.000
R59 Enlarged lymph nodes
0.865 0.135 0.000
M20.4 Other hammer toe(s) (acquired)
0.862 0.138 0.000
M23 Internal derangement of knee
0.861 0.139 0.000
R69 Unknown and unspecified causes of morbidity
0.857 0.143 0.000
R50 Fever of unknown origin
0.855 0.145 0.000
J09-J18 Influenza and pneumonia
0.853 0.147 0.000
Chapter XI Diseases of the digestive system
0.849 0.151 0.000
J40-J47 Chronic lower respiratory diseases
0.845 0.155 0.000
R00 Abnormalities of heart beat
0.838 0.162 0.000
M17 Gonarthrosis [arthrosis of knee]
0.831 0.169 0.000
M45-M49 Spondylopathies
0.828 0.172 0.000
J90-J94 Other diseases of pleura
0.823 0.177 0.000
Chapter IX Diseases of the circulatory system
0.821 0.179 0.000
Chapter VII Diseases of the eye and adnexa
0.820 0.180 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.813 0.187 0.000
M25 Other joint disorders, not elsewhere classified
0.805 0.195 0.000
Chapter VIII Diseases of the ear and mastoid process
0.799 0.201 0.000
M65-M68 Disorders of synovium and tendon
0.794 0.206 0.000
R05 Cough
0.790 0.210 0.000
K40-K46 Hernia
0.787 0.213 0.000
J95-J99 Other diseases of the respiratory system
0.784 0.216 0.000
M40-M43 Deforming dorsopathies
0.776 0.224 0.000
M22 Disorders of patella
0.773 0.227 0.000
R50.9 Fever, unspecified
0.771 0.228 0.000
J18 Pneumonia, organism unspecified
0.771 0.229 0.000
R53 Malaise and fatigue
0.767 0.233 0.000
Chapter I Certain infectious and parasitic diseases
0.767 0.233 0.000
R60 Oedema, not elsewhere classified
0.764 0.236 0.000
M17.1 Other primary gonarthrosis
0.762 0.238 0.000
R59.0 Localised enlarged lymph nodes
0.757 0.243 0.000
K50-K52 Noninfective enteritis and colitis
0.754 0.246 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.754 0.246 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.753 0.247 0.000
J00-J06 Acute upper respiratory infections
0.750 0.250 0.000
J47 Bronchiectasis
0.750 0.250 0.000
M23.3 Other meniscus derangements
0.748 0.252 0.000
M50-M54 Other dorsopathies
0.745 0.255 0.000
R47-R49 Symptoms and signs involving speech and voice
0.742 0.257 0.000
R06.8 Other and unspecified abnormalities of breathing
0.739 0.261 0.000
M19 Other arthrosis
0.734 0.266 0.000
J44 Other chronic obstructive pulmonary disease
0.733 0.267 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.732 0.268 0.000
I30-I52 Other forms of heart disease
0.727 0.273 0.000
M80-M85 Disorders of bone density and structure
0.727 0.273 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.725 0.275 0.000
R00.1 Bradycardia, unspecified
0.725 0.275 0.000
R06.5 Mouth breathing
0.724 0.276 0.000
M24 Other specific joint derangements
0.724 0.276 0.000
M20.2 Hallux rigidus
0.723 0.277 0.000
H04 Disorders of lachrymal system
0.721 0.279 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.712 0.288 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.709 0.291 0.000
Chapter XXII Codes for special purposes
0.707 0.293 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.707 0.293 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.707 0.293 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.706 0.294 0.000
M91-M94 Chondropathies
0.706 0.294 0.000
M86-M90 Other osteopathies
0.706 0.294 0.000
M60-M63 Disorders of muscles
0.706 0.294 0.000
M00-M03 Infectious arthropathies
0.706 0.294 0.000
M20.1 Hallux valgus (acquired)
0.705 0.295 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.704 0.296 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.704 0.296 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.704 0.296 0.000
J30-J39 Other diseases of upper respiratory tract
0.704 0.296 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.699 0.301 0.000
R02 Gangrene, not elsewhere classified
0.699 0.301 0.000
R07 Pain in throat and chest
0.698 0.302 0.000
R04 Haemorrhage from respiratory passages
0.697 0.303 0.000
R68 Other general symptoms and signs
0.696 0.304 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.696 0.304 0.000
R62 Lack of expected normal physiological development
0.696 0.304 0.000
R61 Hyperhidrosis
0.696 0.304 0.000
R57 Shock, not elsewhere classified
0.696 0.304 0.000
R52 Pain, not elsewhere classified
0.696 0.304 0.000
R64 Cachexia
0.696 0.304 0.000
R58 Haemorrhage, not elsewhere classified
0.696 0.304 0.000
R54 Senility
0.696 0.304 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.696 0.304 0.000
M34 Systemic sclerosis
0.696 0.304 0.000
M33 Dermatopolymyositis
0.696 0.304 0.000
M32 Systemic lupus erythematosus
0.696 0.304 0.000
M31 Other necrotising vasculopathies
0.696 0.304 0.000
M30 Polyarteritis nodosa and related conditions
0.696 0.304 0.000
M21 Other acquired deformities of limbs
0.696 0.304 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.696 0.304 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.695 0.305 0.000
J18.1 Lobar pneumonia, unspecified
0.695 0.305 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.694 0.305 0.000
J60-J70 Lung diseases due to external agents
0.694 0.305 0.000
J90 Pleural effusion, not elsewhere classified
0.694 0.306 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.694 0.306 0.000
K40 Inguinal hernia
0.693 0.307 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.693 0.307 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.693 0.307 0.000
R59.1 Generalised enlarged lymph nodes
0.693 0.307 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.691 0.309 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.691 0.309 0.000
R06.7 Sneezing
0.688 0.312 0.000
R06.6 Hiccough
0.688 0.312 0.000
R06.4 Hyperventilation
0.688 0.312 0.000
R06.3 Periodic breathing
0.688 0.312 0.000
R06.2 Wheezing
0.688 0.312 0.000
R06.1 Stridor
0.688 0.312 0.000
K52 Other non-infective gastro-enteritis and colitis
0.686 0.314 0.000
B35-B49 Mycoses
0.685 0.315 0.000
M18 Arthrosis of first carpometacarpal joint
0.683 0.317 0.000
J20-J22 Other acute lower respiratory infections
0.683 0.317 0.000
M47 Spondylosis
0.683 0.317 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.681 0.319 0.000
R63.0 Anorexia
0.676 0.324 0.000
R00.2 Palpitations
0.670 0.330 0.000
M05-M14 Inflammatory polyarthropathies
0.669 0.331 0.000
R01 Cardiac murmurs and other cardiac sounds
0.668 0.332 0.000
Chapter XIV Diseases of the genitourinary system
0.665 0.335 0.000
M17.0 Primary gonarthrosis, bilateral
0.663 0.337 0.000
D50-D53 Nutritional anaemias
0.662 0.338 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.661 0.339 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.661 0.339 0.000
R63.5 Abnormal weight gain
0.661 0.339 0.000
R63.3 Feeding difficulties and mismanagement
0.661 0.339 0.000
R63.2 Polyphagia
0.661 0.339 0.000
R63.1 Polydipsia
0.661 0.339 0.000
Chapter V Mental and behavioural disorders
0.660 0.340 0.000
H04.2 Epiphora
0.658 0.342 0.000
M35 Other systemic involvement of connective tissue
0.657 0.343 0.000
I44 Atrioventricular and left bundle-branch block
0.657 0.343 0.000
M65 Synovitis and tenosynovitis
0.657 0.343 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.655 0.345 0.000
M20.3 Other deformity of hallux (acquired)
0.655 0.345 0.000
M20.0 Deformity of finger(s)
0.655 0.345 0.000
I05-I09 Chronic rheumatic heart diseases
0.655 0.345 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.653 0.347 0.000
H40-H42 Glaucoma
0.652 0.348 0.000
I27 Other pulmonary heart diseases
0.652 0.348 0.000
J98 Other respiratory disorders
0.652 0.348 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.651 0.349 0.000
I60-I69 Cerebrovascular diseases
0.649 0.351 0.000
M25.7 Osteophyte
0.648 0.352 0.000
D60-D64 Aplastic and other anaemias
0.647 0.353 0.000
M48 Other spondylopathies
0.646 0.354 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.645 0.355 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.642 0.358 0.000
M15 Polyarthrosis
0.640 0.360 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.637 0.363 0.000
J92 Pleural plaque
0.635 0.365 0.000
Chapter VI Diseases of the nervous system
0.633 0.366 0.000
M25.5 Pain in joint
0.633 0.367 0.000
J40 Bronchitis, not specified as acute or chronic
0.632 0.368 0.000
M22.4 Chondromalacia patellae
0.632 0.368 0.000
K44 Diaphragmatic hernia
0.630 0.370 0.000
H80-H83 Diseases of inner ear
0.628 0.372 0.000
B37 Candidiasis
0.626 0.373 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.622 0.378 0.000
M17.9 Gonarthrosis, unspecified
0.621 0.379 0.000
R56 Convulsions, not elsewhere classified
0.621 0.379 0.000
R59.9 Enlarged lymph nodes, unspecified
0.620 0.380 0.000
M19.9 Arthrosis, unspecified
0.620 0.380 0.000
H90-H95 Other disorders of ear
0.618 0.381 0.000
Chapter XX External causes of morbidity and mortality
0.618 0.382 0.000
K43 Ventral hernia
0.618 0.382 0.000
M23.9 Internal derangement of knee, unspecified
0.617 0.382 0.000
M23.8 Other internal derangements of knee
0.617 0.382 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.617 0.382 0.000
M23.5 Chronic instability of knee
0.617 0.382 0.000
M23.4 Loose body in knee
0.617 0.382 0.000
M23.1 Discoid meniscus (congenital)
0.617 0.382 0.000
M23.0 Cystic meniscus
0.617 0.382 0.000
R60.0 Localised oedema
0.616 0.384 0.000
R50.8 Other specified fever
0.613 0.387 0.000
R50.2 Drug-induced fever
0.613 0.387 0.000
R50.1 Persistent fever
0.613 0.387 0.000
R50.0 Fever with chills
0.613 0.387 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.612 0.387 0.000
H43-H45 Disorders of vitreous body and globe
0.612 0.388 0.000
J17 Pneumonia in diseases classified elsewhere
0.612 0.388 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.612 0.388 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.612 0.388 0.000
J12 Viral pneumonia, not elsewhere classified
0.612 0.388 0.000
J11 Influenza, virus not identified
0.612 0.388 0.000
J10 Influenza due to identified influenza virus
0.612 0.388 0.000
J14 Pneumonia due to Haemophilus influenzae
0.612 0.388 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.612 0.388 0.000
J09 Influenza due to certain identified influenza virus
0.612 0.388 0.000
K65-K67 Diseases of peritoneum
0.612 0.388 0.000
M50 Cervical disk disorders
0.611 0.388 0.000
K70-K77 Diseases of liver
0.609 0.391 0.000
J41 Simple and mucopurulent chronic bronchitis
0.606 0.394 0.000
J46 Status asthmaticus
0.606 0.394 0.000
J42 Unspecified chronic bronchitis
0.606 0.394 0.000
M41 Scoliosis
0.605 0.395 0.000
K86 Other diseases of pancreas
0.604 0.396 0.000
S20-S29 Injuries to the thorax
0.601 0.399 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.601 0.399 0.000
J18.9 Pneumonia, unspecified
0.601 0.399 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.596 0.403 0.000
M17.5 Other secondary gonarthrosis
0.596 0.404 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.596 0.404 0.000
M17.3 Other posttraumatic gonarthrosis
0.596 0.404 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.596 0.404 0.000
M49 Spondylopathies in diseases classified elsewhere
0.593 0.406 0.000
M46 Other inflammatory spondylopathies
0.593 0.406 0.000
M45 Ankylosing spondylitis
0.593 0.406 0.000
J02 Acute pharyngitis
0.593 0.407 0.000
H53-H54 Visual disturbances and blindness
0.592 0.407 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.592 0.408 0.000
I27.0 Primary pulmonary hypertension
0.592 0.408 0.000
K42 Umbilical hernia
0.591 0.409 0.000
J94 Other pleural conditions
0.590 0.410 0.000
J93 Pneumothorax
0.590 0.410 0.000
J91 Pleural effusion in conditions classified elsewhere
0.590 0.410 0.000
I00-I02 Acute rheumatic fever
0.589 0.411 0.000
H55-H59 Other disorders of eye and adnexa
0.588 0.412 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.588 0.412 0.000
H10-H13 Disorders of conjunctiva
0.588 0.412 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.587 0.412 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.587 0.412 0.000
R47 Speech disturbances, not elsewhere classified
0.585 0.415 0.000
M43 Other deforming dorsopathies
0.584 0.416 0.000
S50-S59 Injuries to the elbow and forearm
0.584 0.416 0.000
D80-D89 Certain disorders involving the immune mechanism
0.583 0.417 0.000
D55-D59 Haemolytic anaemias
0.583 0.417 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.582 0.418 0.000
M70-M79 Other soft tissue disorders
0.581 0.419 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.580 0.420 0.000
H65-H75 Diseases of middle ear and mastoid
0.579 0.421 0.000
M25.9 Joint disorder, unspecified
0.577 0.423 0.000
M25.8 Other specified joint disorders
0.577 0.423 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.577 0.423 0.000
M25.4 Effusion of joint
0.577 0.423 0.000
M25.3 Other instability of joint
0.577 0.423 0.000
M25.2 Flail joint
0.577 0.423 0.000
M25.1 Fistula of joint
0.577 0.423 0.000
M25.0 Haemarthrosis
0.577 0.423 0.000
I51 Complications and ill-defined descriptions of heart disease
0.577 0.423 0.000
B37.0 Candidal stomatitis
0.576 0.424 0.000
K35-K38 Diseases of appendix
0.576 0.424 0.000
H04.1 Other disorders of lachrymal gland
0.576 0.424 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.575 0.424 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.575 0.425 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.575 0.425 0.000
H60-H62 Diseases of external ear
0.573 0.427 0.000
M20.5 Other deformities of toe(s) (acquired)
0.571 0.429 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.569 0.431 0.000
M67 Other disorders of synovium and tendon
0.569 0.431 0.000
M66 Spontaneous rupture of synovium and tendon
0.569 0.431 0.000
R07.3 Other chest pain
0.568 0.432 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.568 0.432 0.000
S80-S89 Injuries to the knee and lower leg
0.568 0.432 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.567 0.432 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.567 0.433 0.000
M47.9 Spondylosis, unspecified
0.566 0.434 0.000
E70-E90 Metabolic disorders
0.565 0.435 0.000
K46 Unspecified abdominal hernia
0.564 0.435 0.000
K45 Other abdominal hernia
0.564 0.435 0.000
K41 Femoral hernia
0.564 0.435 0.000
R04.2 Haemoptysis
0.563 0.437 0.000
H00 Hordeolum and chalazion
0.563 0.437 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.562 0.438 0.000
J96 Respiratory failure, not elsewhere classified
0.562 0.438 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.562 0.438 0.000
J84 Other interstitial pulmonary diseases
0.562 0.438 0.000
K11 Diseases of salivary glands
0.562 0.438 0.000
I44.1 Atrioventricular block, second degree
0.561 0.438 0.000
I31 Other diseases of pericardium
0.561 0.439 0.000
J43 Emphysema
0.560 0.440 0.000
I44.7 Left bundle-branch block, unspecified
0.559 0.441 0.000
M54 Dorsalgia
0.559 0.441 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.558 0.442 0.000
J98.1 Pulmonary collapse
0.557 0.443 0.000
M42 Spinal osteochondrosis
0.556 0.443 0.000
M40 Kyphosis and lordosis
0.556 0.443 0.000
K51 Ulcerative colitis
0.555 0.445 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.555 0.445 0.000
M22.1 Recurrent subluxation of patella
0.554 0.445 0.000
M22.9 Disorder of patella, unspecified
0.554 0.445 0.000
M22.8 Other disorders of patella
0.554 0.445 0.000
M22.3 Other derangements of patella
0.554 0.445 0.000
M22.2 Patellofemoral disorders
0.554 0.445 0.000
M22.0 Recurrent dislocation of patella
0.554 0.445 0.000
D50 Iron deficiency anaemia
0.554 0.446 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.554 0.446 0.000
J18.8 Other pneumonia, organism unspecified
0.552 0.447 0.000
J18.2 Hypostatic pneumonia, unspecified
0.552 0.447 0.000
J18.0 Bronchopneumonia, unspecified
0.552 0.447 0.000
N40-N51 Diseases of male genital organs
0.552 0.448 0.000
R00.0 Tachycardia, unspecified
0.551 0.448 0.000
B99-B99 Other infectious diseases
0.550 0.450 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.550 0.450 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.550 0.450 0.000
B65-B83 Helminthiases
0.550 0.450 0.000
B50-B64 Protozoal diseases
0.550 0.450 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.550 0.450 0.000
B15-B19 Viral hepatitis
0.550 0.450 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.550 0.450 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.550 0.450 0.000
A80-A89 Viral infections of the central nervous system
0.550 0.450 0.000
A75-A79 Rickettsioses
0.550 0.450 0.000
A70-A74 Other diseases caused by chlamydiae
0.550 0.450 0.000
A65-A69 Other spirochaetal diseases
0.550 0.450 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.550 0.450 0.000
A20-A28 Certain zoonotic bacterial diseases
0.550 0.450 0.000
A15-A19 Tuberculosis
0.550 0.450 0.000
N00-N08 Glomerular diseases
0.549 0.451 0.000
R60.9 Oedema, unspecified
0.548 0.452 0.000
R60.1 Generalised oedema
0.548 0.452 0.000
M24.1 Other articular cartilage disorders
0.547 0.453 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.546 0.453 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.543 0.457 0.000
M81 Osteoporosis without pathological fracture
0.542 0.458 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.540 0.459 0.000
H05 Disorders of orbit
0.540 0.459 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.540 0.459 0.000
H01 Other inflammation of eyelid
0.540 0.459 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.540 0.460 0.000
T79-T79 Certain early complications of trauma
0.540 0.460 0.000
T66-T78 Other and unspecified effects of external causes
0.540 0.460 0.000
T33-T35 Frostbite
0.540 0.460 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.540 0.460 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.540 0.460 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.540 0.460 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.540 0.460 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.540 0.460 0.000
T00-T07 Injuries involving multiple body regions
0.540 0.460 0.000
S90-S99 Injuries to the ankle and foot
0.540 0.460 0.000
S40-S49 Injuries to the shoulder and upper arm
0.540 0.460 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.540 0.460 0.000
S10-S19 Injuries to the neck
0.540 0.460 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.540 0.460 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.538 0.461 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.538 0.462 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.538 0.462 0.000
J04 Acute laryngitis and tracheitis
0.538 0.462 0.000
J03 Acute tonsillitis
0.538 0.462 0.000
J01 Acute sinusitis
0.538 0.462 0.000
J00 Acute nasopharyngitis [common cold]
0.538 0.462 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.536 0.464 0.000
M23.37 Other meniscus derangements-Capsular lig
0.536 0.464 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.536 0.464 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.536 0.464 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.536 0.464 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.536 0.464 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.536 0.464 0.000
J34 Other disorders of nose and nasal sinuses
0.536 0.464 0.000
I07 Rheumatic tricuspid valve diseases
0.536 0.464 0.000
M25.77 Osteophyte (Ankle and foot)
0.535 0.465 0.000
R51 Headache
0.535 0.465 0.000
M53 Other dorsopathies, not elsewhere classified
0.534 0.465 0.000
K81 Cholecystitis
0.534 0.465 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.534 0.466 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.533 0.467 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.532 0.468 0.000
H40 Glaucoma
0.532 0.468 0.000
B95-B98 Bacterial, viral and other infectious agents
0.532 0.468 0.000
R03.1 Nonspecific low blood-pressure reading
0.531 0.469 0.000
K82 Other diseases of gallbladder
0.530 0.470 0.000
I67 Other cerebrovascular diseases
0.530 0.470 0.000
I73 Other peripheral vascular diseases
0.529 0.471 0.000
E00-E07 Disorders of thyroid gland
0.528 0.472 0.000
M19.8 Other specified arthrosis
0.526 0.474 0.000
M19.2 Other secondary arthrosis
0.526 0.474 0.000
M19.1 Posttraumatic arthrosis of other joints
0.526 0.474 0.000
M19.0 Primary arthrosis of other joints
0.526 0.474 0.000
I27.2 Other secondary pulmonary hypertension
0.526 0.474 0.000
K90-K93 Other diseases of the digestive system
0.526 0.474 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.525 0.474 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.525 0.475 0.000
J81 Pulmonary oedema
0.525 0.475 0.000
J80 Adult respiratory distress syndrome
0.525 0.475 0.000
M25.51 Pain in joint (Shoulder region)
0.525 0.475 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.524 0.476 0.000
N20-N23 Urolithiasis
0.524 0.476 0.000
K50 Crohn's disease [regional enteritis]
0.522 0.477 0.000
K13 Other diseases of lip and oral mucosa
0.522 0.478 0.000
S70-S79 Injuries to the hip and thigh
0.521 0.479 0.000
I52 Other heart disorders in diseases classified elsewhere
0.521 0.479 0.000
I49 Other cardiac arrhythmias
0.521 0.479 0.000
I48 Atrial fibrillation and flutter
0.521 0.479 0.000
I46 Cardiac arrest
0.521 0.479 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.521 0.479 0.000
I42 Cardiomyopathy
0.521 0.479 0.000
I41 Myocarditis in diseases classified elsewhere
0.521 0.479 0.000
I40 Acute myocarditis
0.521 0.479 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.521 0.479 0.000
I37 Pulmonary valve disorders
0.521 0.479 0.000
I36 Nonrheumatic tricuspid valve disorders
0.521 0.479 0.000
I33 Acute and subacute endocarditis
0.521 0.479 0.000
I32 Pericarditis in diseases classified elsewhere
0.521 0.479 0.000
I30 Acute pericarditis
0.521 0.479 0.000
I38 Endocarditis, valve unspecified
0.521 0.479 0.000
M85 Other disorders of bone density and structure
0.521 0.479 0.000
M84 Disorders of continuity of bone
0.521 0.479 0.000
M83 Adult osteomalacia
0.521 0.479 0.000
M82 Osteoporosis in diseases classified elsewhere
0.521 0.479 0.000
M80 Osteoporosis with pathological fracture
0.521 0.479 0.000
H20 Iridocyclitis
0.520 0.479 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.520 0.480 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.520 0.480 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.520 0.480 0.000
M24.9 Joint derangement, unspecified
0.519 0.481 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.519 0.481 0.000
M24.7 Protrusio acetabuli
0.519 0.481 0.000
M24.6 Ankylosis of joint
0.519 0.481 0.000
M24.5 Contracture of joint
0.519 0.481 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.519 0.481 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.519 0.481 0.000
M24.2 Disorder of ligament
0.519 0.481 0.000
M24.0 Loose body in joint
0.519 0.481 0.000
I50 Heart failure
0.519 0.481 0.000
I34 Nonrheumatic mitral valve disorders
0.518 0.482 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.518 0.482 0.000
H04.9 Disorder of lachrymal system, unspecified
0.517 0.483 0.000
H04.8 Other disorders of lachrymal system
0.517 0.483 0.000
H04.6 Other changes in lachrymal passages
0.517 0.483 0.000
H04.4 Chronic inflammation of lachrymal passages
0.517 0.483 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.517 0.483 0.000
H04.0 Dacryoadenitis
0.517 0.483 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.516 0.484 0.000
M48.0 Spinal stenosis
0.516 0.484 0.000
E50-E64 Other nutritional deficiencies
0.516 0.484 0.000
M50.0 Cervical disk disorder with myelopathy
0.516 0.484 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.515 0.485 0.000
R49 Voice disturbances
0.513 0.486 0.000
A30-A49 Other bacterial diseases
0.513 0.487 0.000
K01 Embedded and impacted teeth
0.513 0.487 0.000
R07.4 Chest pain, unspecified
0.512 0.488 0.000
M47.8 Other spondylosis
0.511 0.489 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.510 0.489 0.000
K85 Acute pancreatitis
0.510 0.489 0.000
K83 Other diseases of biliary tract
0.510 0.489 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.509 0.491 0.000
I47 Paroxysmal tachycardia
0.509 0.491 0.000
I28 Other diseases of pulmonary vessels
0.508 0.491 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.508 0.491 0.000
H93 Other disorders of ear, not elsewhere classified
0.508 0.492 0.000
N25-N29 Other disorders of kidney and ureter
0.508 0.492 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.508 0.492 0.000
P90-P96 Other disorders originating in the perinatal period
0.507 0.493 0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.507 0.493 0.000
P75-P78 Digestive system disorders of fetus and newborn
0.507 0.493 0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.507 0.493 0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.507 0.493 0.000
P35-P39 Infections specific to the perinatal period
0.507 0.493 0.000
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.507 0.493 0.000
P10-P15 Birth trauma
0.507 0.493 0.000
P05-P08 Disorders related to length of gestation and fetal growth
0.507 0.493 0.000
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.507 0.493 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.507 0.493 0.000
Q80-Q89 Other congenital malformations
0.507 0.493 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.507 0.493 0.000
Q60-Q64 Congenital malformations of the urinary system
0.507 0.493 0.000
Q50-Q56 Congenital malformations of genital organs
0.507 0.493 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.507 0.493 0.000
Q35-Q37 Cleft lip and cleft palate
0.507 0.493 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.507 0.493 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.507 0.493 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.507 0.493 0.000
Q00-Q07 Congenital malformations of the nervous system
0.507 0.493 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.507 0.493 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.507 0.493 0.000
S00-S09 Injuries to the head
0.507 0.493 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.506 0.494 0.000
M02 Reactive arthropathies
0.506 0.494 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.506 0.494 0.000
M00 Pyogenic arthritis
0.506 0.494 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.506 0.494 0.000
M62 Other disorders of muscle
0.506 0.494 0.000
M61 Calcification and ossification of muscle
0.506 0.494 0.000
M60 Myositis
0.506 0.494 0.000
M90 Osteopathies in diseases classified elsewhere
0.506 0.494 0.000
M89 Other disorders of bone
0.506 0.494 0.000
M88 Paget's disease of bone [osteitis deformans]
0.506 0.494 0.000
M87 Osteonecrosis
0.506 0.494 0.000
M86 Osteomyelitis
0.506 0.494 0.000
M94 Other disorders of cartilage
0.506 0.494 0.000
M93 Other osteochondropathies
0.506 0.494 0.000
M92 Other juvenile osteochondrosis
0.506 0.494 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.506 0.494 0.000
M99 Biomechanical lesions, not elsewhere classified
0.506 0.494 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.506 0.494 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.506 0.494 0.000
R82 Other abnormal findings in urine
0.505 0.495 0.000
R81 Glycosuria
0.505 0.495 0.000
R80 Isolated proteinuria
0.505 0.495 0.000
R89 Abnormal findings in specimens from other organs, systems and tissues
0.505 0.495 0.000
R87 Abnormal findings in specimens from female genital organs
0.505 0.495 0.000
R86 Abnormal findings in specimens from male genital organs
0.505 0.495 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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