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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10456057
log Bayes Factor = 140.044
Chromosome 6   position 31,245,534  (GRCh37) Explore rs10456057 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M07.39 Other psoriatic arthropathies (Site unspecified)
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
L40.0 Psoriasis vulgaris
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M07.3 Other psoriatic arthropathies
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.001 0.999
E10 Insulin-dependent diabetes mellitus
0.000 0.001 0.999
E10.9 Without complications
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.002 0.998
M07.30 Other psoriatic arthropathies (Multiple sites)
0.995 0.005 0.000
E10-E14 Diabetes mellitus
0.000 0.008 0.992
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.008 0.992
E05.9 Thyrotoxicosis, unspecified
0.000 0.014 0.986
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.025 0.975
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.071 0.929
E10.3 With ophthalmic complications
0.000 0.075 0.925
E07 Other disorders of thyroid
0.000 0.078 0.922
E10.4 With neurological complications
0.000 0.086 0.914
E10.1 With ketoacidosis
0.000 0.113 0.887
E16 Other disorders of pancreatic internal secretion
0.000 0.115 0.885
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.876 0.124 0.000
L40.8 Other psoriasis
0.872 0.128 0.000
L40.1 Generalised pustular psoriasis
0.872 0.128 0.000
M07.38 Other psoriatic arthropathies (Other)
0.864 0.136 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.861 0.139 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.140 0.860
E16.2 Hypoglycaemia, unspecified
0.000 0.140 0.860
M07.36 Other psoriatic arthropathies (Lower leg)
0.846 0.154 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.838 0.162 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.838 0.162 0.000
E10.2 With renal complications
0.000 0.165 0.835
L40.4 Guttate psoriasis
0.820 0.180 0.000
E10.5 With peripheral circulatory complications
0.000 0.187 0.813
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.269 0.731
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.717 0.283 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.284 0.716
E10.6 With other specified complications
0.000 0.284 0.716
E10.0 With coma
0.000 0.284 0.716
E05.8 Other thyrotoxicosis
0.000 0.285 0.715
E05.5 Thyroid crisis or storm
0.000 0.285 0.715
E05.4 Thyrotoxicosis factitia
0.000 0.285 0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.285 0.715
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.285 0.715
E10.8 With unspecified complications
0.000 0.288 0.712
E12 Malnutrition-related diabetes mellitus
0.000 0.289 0.711
E20-E35 Disorders of other endocrine glands
0.000 0.306 0.694
E04 Other non-toxic goitre
0.000 0.314 0.686
E07.8 Other specified disorders of thyroid
0.000 0.316 0.684
E40-E46 Malnutrition
0.000 0.319 0.681
E06 Thyroiditis
0.000 0.330 0.670
E15 Nondiabetic hypoglycaemic coma
0.000 0.334 0.666
E07.1 Dyshormogenetic goitre
0.000 0.339 0.661
E07.0 Hypersecretion of calcitonin
0.000 0.339 0.661
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.366 0.634
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.366 0.634
E16.4 Abnormal secretion of gastrin
0.000 0.366 0.634
E16.3 Increased secretion of glucagon
0.000 0.366 0.634
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.366 0.634
E13 Other specified diabetes mellitus
0.000 0.380 0.620
E04.9 Non-toxic goitre, unspecified
0.000 0.391 0.609
E28 Ovarian dysfunction
0.000 0.417 0.583
E29 Testicular dysfunction
0.000 0.419 0.581
E16.1 Other hypoglycaemia
0.000 0.434 0.566
E27 Other disorders of adrenal gland
0.000 0.434 0.566
E14 Unspecified diabetes mellitus
0.000 0.438 0.562
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.440 0.560
E20 Hypoparathyroidism
0.000 0.455 0.545
E34 Other endocrine disorders
0.000 0.457 0.543
E27.1 Primary adrenocortical insufficiency
0.000 0.457 0.543
E65-E68 Obesity and other hyperalimentation
0.000 0.482 0.518
E50-E64 Other nutritional deficiencies
0.000 0.484 0.516
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E03.8 Other specified hypothyroidism
0.000 0.486 0.513
E12.9 Without complications
0.000 0.490 0.510
E12.8 With unspecified complications
0.000 0.490 0.510
E12.7 With multiple complications
0.000 0.490 0.510
E12.6 With other specified complications
0.000 0.490 0.510
E12.5 With peripheral circulatory complications
0.000 0.490 0.510
E12.4 With neurological complications
0.000 0.490 0.510
E12.3 With ophthalmic complications
0.000 0.490 0.510
E12.2 With renal complications
0.000 0.490 0.510
E12.1 With ketoacidosis
0.000 0.490 0.510
E12.0 With coma
0.000 0.490 0.510
E29.1 Testicular hypofunction
0.000 0.500 0.500
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.502 0.498
E32 Diseases of thymus
0.000 0.502 0.498
E31 Polyglandular dysfunction
0.000 0.502 0.498
E30 Disorders of puberty, not elsewhere classified
0.000 0.502 0.498
E28.2 Polycystic ovarian syndrome
0.000 0.505 0.494
E04.8 Other specified non-toxic goitre
0.000 0.508 0.492
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.512 0.488
E45 Retarded development following protein-energy malnutrition
0.000 0.512 0.488
E43 Unspecified severe protein-energy malnutrition
0.000 0.512 0.488
E42 Marasmic kwashiorkor
0.000 0.512 0.488
E41 Nutritional marasmus
0.000 0.512 0.488
E40 Kwashiorkor
0.000 0.512 0.488
E06.5 Other chronic thyroiditis
0.000 0.520 0.480
E06.4 Drug-induced thyroiditis
0.000 0.520 0.480
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.520 0.480
E06.1 Subacute thyroiditis
0.000 0.520 0.480
E06.0 Acute thyroiditis
0.000 0.520 0.480
E06.9 Thyroiditis, unspecified
0.000 0.525 0.475
E26 Hyperaldosteronism
0.000 0.525 0.475
E22 Hyperfunction of pituitary gland
0.000 0.533 0.467
E46 Unspecified protein-energy malnutrition
0.000 0.542 0.457
E13.8 With unspecified complications
0.000 0.555 0.445
E13.7 With multiple complications
0.000 0.555 0.445
E13.6 With other specified complications
0.000 0.555 0.445
E13.5 With peripheral circulatory complications
0.000 0.555 0.445
E13.4 With neurological complications
0.000 0.555 0.445
E13.3 With ophthalmic complications
0.000 0.555 0.445
E13.2 With renal complications
0.000 0.555 0.445
E13.1 With ketoacidosis
0.000 0.555 0.445
E13.0 With coma
0.000 0.555 0.445
E14.3 With ophthalmic complications
0.000 0.557 0.443
K90 Intestinal malabsorption
0.000 0.558 0.442
E06.3 Autoimmune thyroiditis
0.000 0.561 0.439
E20.9 Hypoparathyroidism, unspecified
0.000 0.562 0.437
E28.3 Primary ovarian failure
0.000 0.566 0.433
E04.0 Non-toxic diffuse goitre
0.000 0.573 0.427
M07 Psoriatic and enteropathic arthropathies
0.423 0.576 0.001
E34.9 Endocrine disorder, unspecified
0.000 0.580 0.420
E04.2 Non-toxic multinodular goitre
0.000 0.580 0.420
E28.9 Ovarian dysfunction, unspecified
0.000 0.582 0.418
E28.8 Other ovarian dysfunction
0.000 0.582 0.418
E28.1 Androgen excess
0.000 0.582 0.418
E28.0 Oestrogen excess
0.000 0.582 0.418
E29.9 Testicular dysfunction, unspecified
0.000 0.583 0.416
E29.8 Other testicular dysfunction
0.000 0.583 0.416
E29.0 Testicular hyperfunction
0.000 0.583 0.416
E24 Cushing's syndrome
0.000 0.584 0.416
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.589 0.411
E34.0 Carcinoid syndrome
0.000 0.592 0.408
E27.5 Adrenomedullary hyperfunction
0.000 0.594 0.406
E27.0 Other adrenocortical overactivity
0.000 0.594 0.406
E25 Adrenogenital disorders
0.001 0.597 0.403
E14.8 With unspecified complications
0.000 0.597 0.403
E14.7 With multiple complications
0.000 0.597 0.403
E14.6 With other specified complications
0.000 0.597 0.403
E14.5 With peripheral circulatory complications
0.000 0.597 0.403
E14.2 Withrenal complications
0.000 0.597 0.403
E14.1 With ketoacidosis
0.000 0.597 0.403
E14.0 With coma
0.000 0.597 0.403
E20.8 Other hypoparathyroidism
0.000 0.609 0.391
E20.1 Pseudohypoparathyroidism
0.000 0.609 0.391
E20.0 Idiopathic hypoparathyroidism
0.000 0.609 0.391
E27.2 Addisonian crisis
0.000 0.609 0.390
E34.8 Other specified endocrine disorders
0.000 0.610 0.390
E34.5 Androgen resistance syndrome
0.000 0.610 0.390
E34.4 Constitutional tall stature
0.000 0.610 0.390
E34.3 Short stature, not elsewhere classified
0.000 0.610 0.390
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.610 0.390
E34.1 Other hypersecretion of intestinal hormones
0.000 0.610 0.390
E04.1 Non-toxic single thyroid nodule
0.000 0.626 0.374
E61 Deficiency of other nutrient elements
0.000 0.628 0.372
E67 Other hyperalimentation
0.000 0.628 0.372
E68 Sequelae of hyperalimentation
0.000 0.628 0.372
E65 Localised adiposity
0.000 0.629 0.371
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.630 0.370
E63 Other nutritional deficiencies
0.000 0.630 0.370
E56 Other vitamin deficiencies
0.000 0.630 0.370
E51 Thiamine deficiency
0.000 0.630 0.370
E50 Vitamin A deficiency
0.000 0.630 0.370
E60 Dietary zinc deficiency
0.000 0.630 0.370
E59 Dietary selenium deficiency
0.000 0.630 0.370
E58 Dietary calcium deficiency
0.000 0.630 0.370
E54 Ascorbic acid deficiency
0.000 0.630 0.370
E52 Niacin deficiency [pellagra]
0.000 0.630 0.370
E14.4 With neurological complications
0.000 0.631 0.369
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.631 0.368
E22.1 Hyperprolactinaemia
0.000 0.635 0.365
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.638 0.361
E30.9 Disorder of puberty, unspecified
0.000 0.643 0.357
E30.8 Other disorders of puberty
0.000 0.643 0.357
E30.1 Precocious puberty
0.000 0.643 0.357
E30.0 Delayed puberty
0.000 0.643 0.357
E31.9 Polyglandular dysfunction, unspecified
0.000 0.643 0.357
E31.8 Other polyglandular dysfunction
0.000 0.643 0.357
E31.1 Polyglandular hyperfunction
0.000 0.643 0.357
E31.0 Autoimmune polyglandular failure
0.000 0.643 0.357
E32.9 Disease of thymus, unspecified
0.000 0.643 0.357
E32.8 Other diseases of thymus
0.000 0.643 0.357
E32.1 Abscess of thymus
0.000 0.643 0.357
E32.0 Persistent hyperplasia of thymus
0.000 0.643 0.357
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.643 0.357
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.643 0.357
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.643 0.357
E22.0 Acromegaly and pituitary gigantism
0.000 0.646 0.354
E13.9 Without complications
0.000 0.646 0.353
E44.1 Mild protein-energy malnutrition
0.000 0.650 0.350
E44.0 Moderate protein-energy malnutrition
0.000 0.650 0.350
E26.9 Hyperaldosteronism, unspecified
0.000 0.659 0.341
E26.8 Other hyperaldosteronism
0.000 0.659 0.341
E26.1 Secondary hyperaldosteronism
0.000 0.659 0.341
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.665 0.335
E22.8 Other hyperfunction of pituitary gland
0.000 0.665 0.335
E27.9 Disorder of adrenal gland, unspecified
0.000 0.670 0.330
E27.8 Other specified disorders of adrenal gland
0.000 0.681 0.319
K90.9 Intestinal malabsorption, unspecified
0.000 0.681 0.319
E26.0 Primary hyperaldosteronism
0.000 0.682 0.318
K90.8 Other intestinal malabsorption
0.000 0.683 0.317
K90.3 Pancreatic steatorrhoea
0.000 0.683 0.317
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.683 0.317
K90.1 Tropical sprue
0.000 0.683 0.317
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.694 0.306
M07.6 Other enteropathic arthropathies
0.303 0.696 0.001
M07.5 Arthropathy in ulcerative colitis
0.303 0.696 0.001
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.303 0.696 0.001
M07.2 Psoriatic spondylitis
0.303 0.696 0.001
M07.1 Arthritis mutilans
0.303 0.696 0.001
M07.0 Distal interphalangeal psoriatic arthropathy
0.303 0.696 0.001
E53 Deficiency of other B group vitamins
0.000 0.699 0.301
E24.8 Other Cushing's syndrome
0.000 0.702 0.298
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.702 0.298
E24.3 Ectopic ACTH syndrome
0.000 0.702 0.298
E24.2 Drug-induced Cushing's syndrome
0.000 0.702 0.298
E24.1 Nelson's syndrome
0.000 0.702 0.298
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.705 0.294
E21.4 Other specified disorders of parathyroid gland
0.000 0.705 0.294
E21.2 Other hyperparathyroidism
0.000 0.705 0.294
E25.9 Adrenogenital disorder, unspecified
0.001 0.711 0.289
E25.8 Other adrenogenital disorders
0.001 0.711 0.289
E55 Vitamin D deficiency
0.000 0.719 0.281
E24.9 Cushing's syndrome, unspecified
0.000 0.720 0.280
E21.0 Primary hyperparathyroidism
0.000 0.721 0.279
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.726 0.274
L40-L45 Papulosquamous disorders
0.269 0.731 0.000
E61.1 Iron deficiency
0.000 0.731 0.268
E61.9 Deficiency of nutrient element, unspecified
0.000 0.733 0.267
E61.8 Deficiency of other specified nutrient elements
0.000 0.733 0.267
E61.7 Deficiency of multiple nutrient elements
0.000 0.733 0.267
E61.6 Vanadium deficiency
0.000 0.733 0.267
E61.5 Molybdenum deficiency
0.000 0.733 0.267
E61.4 Chromium deficiency
0.000 0.733 0.267
E61.3 Manganese deficiency
0.000 0.733 0.267
E61.2 Magnesium deficiency
0.000 0.733 0.267
E61.0 Copper deficiency
0.000 0.733 0.267
E67.8 Other specified hyperalimentation
0.000 0.733 0.267
E67.3 Hypervitaminosis D
0.000 0.733 0.267
E67.2 Megavitamin-B6 syndrome
0.000 0.733 0.267
E67.1 Hypercarotenaemia
0.000 0.733 0.267
E67.0 Hypervitaminosis A
0.000 0.733 0.267
E50.9 Vitamin A deficiency, unspecified
0.000 0.734 0.265
E50.8 Other manifestations of vitamin A deficiency
0.000 0.734 0.265
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.734 0.265
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.734 0.265
E50.5 Vitamin A deficiency with night blindness
0.000 0.734 0.265
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.734 0.265
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.734 0.265
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.734 0.265
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.734 0.265
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.734 0.265
E51.9 Thiamine deficiency, unspecified
0.000 0.734 0.265
E51.8 Other manifestations of thiamine deficiency
0.000 0.734 0.265
E51.2 Wernicke's encephalopathy
0.000 0.734 0.265
E51.1 Beriberi
0.000 0.734 0.265
E56.9 Vitamin deficiency, unspecified
0.000 0.734 0.265
E56.8 Deficiency of other vitamins
0.000 0.734 0.265
E56.1 Deficiency of vitamin K
0.000 0.734 0.265
E56.0 Deficiency of vitamin E
0.000 0.734 0.265
E63.9 Nutritional deficiency, unspecified
0.000 0.734 0.265
E63.8 Other specified nutritional deficiencies
0.000 0.734 0.265
E63.1 Imbalance of constituents of food intake
0.000 0.734 0.265
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.734 0.265
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.734 0.265
E64.8 Sequelae of other nutritional deficiencies
0.000 0.734 0.265
E64.3 Sequelae of rickets
0.000 0.734 0.265
E64.2 Sequelae of vitamin C deficiency
0.000 0.734 0.265
E64.1 Sequelae of vitamin A deficiency
0.000 0.734 0.265
E64.0 Sequelae of protein-energy malnutrition
0.000 0.734 0.265
E23 Hypofunction and other disorders of pituitary gland
0.001 0.738 0.261
E21.3 Hyperparathyroidism, unspecified
0.000 0.742 0.258
E24.0 Pituitary-dependent Cushing's disease
0.001 0.757 0.243
E14.9 Without complications
0.000 0.778 0.222
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.779 0.220
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.218 0.782 0.001
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.218 0.782 0.001
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.218 0.782 0.001
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.218 0.782 0.001
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.218 0.782 0.001
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.218 0.782 0.001
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.218 0.782 0.001
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.218 0.782 0.001
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.218 0.782 0.001
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.218 0.782 0.001
M07.19 Arthritis mutilans (Site unspecified)
0.218 0.782 0.001
M07.18 Arthritis mutilans (Other)
0.218 0.782 0.001
M07.17 Arthritis mutilans (Ankle and foot)
0.218 0.782 0.001
M07.16 Arthritis mutilans (Lower leg)
0.218 0.782 0.001
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.218 0.782 0.001
M07.14 Arthritis mutilans (Hand)
0.218 0.782 0.001
M07.13 Arthritis mutilans (Forearm)
0.218 0.782 0.001
M07.12 Arthritis mutilans (Upper arm)
0.218 0.782 0.001
M07.11 Arthritis mutilans (Shoulder region)
0.218 0.782 0.001
M07.10 Arthritis mutilans (Multiple sites)
0.218 0.782 0.001
M07.29 Psoriatic spondylitis (Site unspecified)
0.218 0.782 0.001
M07.28 Psoriatic spondylitis (Other)
0.218 0.782 0.001
M07.27 Psoriatic spondylitis (Ankle and foot)
0.218 0.782 0.001
M07.26 Psoriatic spondylitis (Lower leg)
0.218 0.782 0.001
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.218 0.782 0.001
M07.24 Psoriatic spondylitis (Hand)
0.218 0.782 0.001
M07.23 Psoriatic spondylitis (Forearm)
0.218 0.782 0.001
M07.22 Psoriatic spondylitis (Upper arm)
0.218 0.782 0.001
M07.21 Psoriatic spondylitis (Shoulder region)
0.218 0.782 0.001
M07.20 Psoriatic spondylitis (Multiple sites)
0.218 0.782 0.001
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.218 0.782 0.001
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.218 0.782 0.001
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.218 0.782 0.001
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.218 0.782 0.001
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.218 0.782 0.001
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.218 0.782 0.001
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.218 0.782 0.001
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.218 0.782 0.001
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.218 0.782 0.001
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.218 0.782 0.001
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.218 0.782 0.001
M07.58 Arthropathy in ulcerative colitis (Other)
0.218 0.782 0.001
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.218 0.782 0.001
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.218 0.782 0.001
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.218 0.782 0.001
M07.54 Arthropathy in ulcerative colitis (Hand)
0.218 0.782 0.001
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.218 0.782 0.001
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.218 0.782 0.001
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.218 0.782 0.001
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.218 0.782 0.001
M07.69 Other enteropathic arthropathies (Site unspecified)
0.218 0.782 0.001
M07.68 Other enteropathic arthropathies (Other)
0.218 0.782 0.001
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.218 0.782 0.001
M07.66 Other enteropathic arthropathies (Lower leg)
0.218 0.782 0.001
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.218 0.782 0.001
M07.64 Other enteropathic arthropathies (Hand)
0.218 0.782 0.001
M07.63 Other enteropathic arthropathies (Forearm)
0.218 0.782 0.001
M07.62 Other enteropathic arthropathies (Upper arm)
0.218 0.782 0.001
M07.61 Other enteropathic arthropathies (Shoulder region)
0.218 0.782 0.001
M07.60 Other enteropathic arthropathies (Multiple sites)
0.218 0.782 0.001
E53.9 Vitamin B deficiency, unspecified
0.000 0.784 0.216
E53.1 Pyridoxine deficiency
0.000 0.784 0.216
E53.0 Riboflavin deficiency
0.000 0.784 0.216
E23.2 Diabetes insipidus
0.001 0.795 0.205
L42 Pityriasis rosea
0.202 0.798 0.000
E55.0 Rickets, active
0.000 0.798 0.202
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.001 0.806 0.193
L44 Other papulosquamous disorders
0.193 0.807 0.000
L41 Parapsoriasis
0.193 0.807 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.193 0.807 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.001 0.812 0.187
E23.1 Drug-induced hypopituitarism
0.001 0.812 0.187
E66 Obesity
0.000 0.820 0.180
E23.6 Other disorders of pituitary gland
0.001 0.821 0.178
E53.8 Deficiency of other specified B group vitamins
0.000 0.853 0.147
L41.9 Parapsoriasis, unspecified
0.138 0.861 0.000
L41.8 Other parapsoriasis
0.138 0.861 0.000
L41.5 Retiform parapsoriasis
0.138 0.861 0.000
L41.4 Large plaque parapsoriasis
0.138 0.861 0.000
L41.3 Small plaque parapsoriasis
0.138 0.861 0.000
L41.2 Lymphomatoid papulosis
0.138 0.861 0.000
L41.1 Pityriasis lichenoides chronica
0.138 0.861 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.138 0.861 0.000
L44.9 Papulosquamous disorder, unspecified
0.138 0.861 0.000
L44.8 Other specified papulosquamous disorders
0.138 0.861 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.138 0.861 0.000
L44.3 Lichen ruber moniliformis
0.138 0.861 0.000
L44.2 Lichen striatus
0.138 0.861 0.000
L44.1 Lichen nitidus
0.138 0.861 0.000
L44.0 Pityriasis rubra pilaris
0.138 0.861 0.000
E66.8 Other obesity
0.000 0.862 0.138
E66.1 Drug-induced obesity
0.000 0.870 0.129
E66.0 Obesity due to excess calories
0.000 0.885 0.115
E23.7 Disorder of pituitary gland, unspecified
0.002 0.885 0.113
E55.9 Vitamin D deficiency, unspecified
0.000 0.887 0.112
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.889 0.111
L43 Lichen planus
0.099 0.900 0.001
E23.0 Hypopituitarism
0.001 0.916 0.082
K50.0 Crohn's disease of small intestine
0.078 0.922 0.000
L43.3 Subacute (active) lichen planus
0.071 0.928 0.001
L43.2 Lichenoid drug reaction
0.071 0.928 0.001
L43.1 Bullous lichen planus
0.071 0.928 0.001
L43.0 Hypertrophic lichen planus
0.071 0.928 0.001
E11 Non-insulin-dependent diabetes mellitus
0.000 0.928 0.072
K90-K93 Other diseases of the digestive system
0.000 0.931 0.069
M35.0 Sicca syndrome [Sjogren]
0.000 0.932 0.068
K50 Crohn's disease [regional enteritis]
0.067 0.933 0.000
K50.9 Crohn's disease, unspecified
0.063 0.937 0.000
K50.8 Other Crohn's disease
0.062 0.938 0.000
M35.3 Polymyalgia rheumatica
0.000 0.940 0.060
M35 Other systemic involvement of connective tissue
0.000 0.940 0.060
L43.8 Other lichen planus
0.055 0.944 0.001
E11.8 With unspecified complications
0.000 0.944 0.056
H26.9 Cataract, unspecified
0.000 0.945 0.055
E11.5 With peripheral circulatory complications
0.000 0.946 0.054
E11.6 With other specified complications
0.000 0.948 0.052
H26 Other cataract
0.000 0.948 0.052
E11.7 With multiple complications
0.000 0.948 0.051
E11.0 With coma
0.000 0.949 0.050
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.950 0.049
M35.1 Other overlap syndromes
0.000 0.953 0.047
H26.4 After-cataract
0.000 0.953 0.047
K91.4 Colostomy and enterostomy malfunction
0.000 0.955 0.045
H26.2 Complicated cataract
0.000 0.955 0.045
H26.8 Other specified cataract
0.000 0.956 0.044
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.956 0.044
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.957 0.043
M35.8 Other specified systemic involvement of connective tissue
0.000 0.957 0.043
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.957 0.043
M35.5 Multifocal fibrosclerosis
0.000 0.957 0.043
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.957 0.043
M35.2 Behcet's disease
0.000 0.957 0.043
J47 Bronchiectasis
0.000 0.958 0.042
E11.3 With ophthalmic complications
0.000 0.961 0.039
M35.7 Hypermobility syndrome
0.000 0.961 0.039
H26.1 Traumatic cataract
0.000 0.962 0.038
E11.2 With renal complications
0.000 0.962 0.038
K50.1 Crohn's disease of large intestine
0.038 0.962 0.000
H26.0 Infantile, juvenile and presenile cataract
0.000 0.962 0.038
H26.3 Drug-induced cataract
0.000 0.962 0.037
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.964 0.036
K93.1 Megacolon in Chagas' disease
0.000 0.964 0.036
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.964 0.036
E11.1 With ketoacidosis
0.000 0.966 0.034
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.969 0.031
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.969 0.031
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.970 0.030
E70-E90 Metabolic disorders
0.000 0.971 0.029
K91.5 Postcholecystectomy syndrome
0.000 0.971 0.029
K83.1 Obstruction of bile duct
0.028 0.972 0.000
J33.0 Polyp of nasal cavity
0.000 0.973 0.027
J33 Nasal polyp
0.000 0.974 0.026
E73 Lactose intolerance
0.000 0.975 0.025
J33.9 Nasal polyp, unspecified
0.000 0.975 0.025
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.975 0.024
K83 Other diseases of biliary tract
0.025 0.975 0.000
J33.8 Other polyp of sinus
0.000 0.975 0.025
K83.8 Other specified diseases of biliary tract
0.024 0.976 0.000
K91.1 Postgastric surgery syndromes
0.000 0.977 0.022
H25-H28 Disorders of lens
0.000 0.977 0.023
E74 Other disorders of carbohydrate metabolism
0.000 0.978 0.022
E73.9 Lactose intolerance, unspecified
0.000 0.978 0.022
E85 Amyloidosis
0.000 0.978 0.022
L43.9 Lichen planus, unspecified
0.021 0.978 0.001
E84 Cystic fibrosis
0.000 0.979 0.021
E79 Disorders of purine and pyrimidine metabolism
0.000 0.979 0.021
E77 Disorders of glycoprotein metabolism
0.000 0.979 0.021
E76 Disorders of glycosaminoglycan metabolism
0.000 0.979 0.021
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.979 0.021
E72 Other disorders of amino-acid metabolism
0.000 0.979 0.021
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.979 0.021
E70 Disorders of aromatic amino-acid metabolism
0.000 0.979 0.021
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.979 0.021
H27 Other disorders of lens
0.000 0.980 0.020
K91.3 Postoperative intestinal obstruction
0.000 0.981 0.019
K83.3 Fistula of bile duct
0.019 0.981 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.981 0.019
K83.0 Cholangitis
0.019 0.981 0.000
J33.1 Polypoid sinus degeneration
0.000 0.981 0.019
K83.9 Disease of biliary tract, unspecified
0.018 0.982 0.000
E73.8 Other lactose intolerance
0.000 0.982 0.018
E73.1 Secondary lactase deficiency
0.000 0.982 0.018
E73.0 Congenital lactase deficiency
0.000 0.982 0.018
K83.5 Biliary cyst
0.018 0.982 0.000
K83.4 Spasm of sphincter of Oddi
0.018 0.982 0.000
K83.2 Perforation of bile duct
0.018 0.982 0.000
H27.1 Dislocation of lens
0.000 0.982 0.018
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.983 0.017
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.983 0.017
E85.9 Amyloidosis, unspecified
0.000 0.983 0.017
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.983 0.017
E11.4 With neurological complications
0.000 0.983 0.016
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.000 0.983 0.016
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.984 0.016
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.984 0.016
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.984 0.016
E74.2 Disorders of galactose metabolism
0.000 0.984 0.016
E74.1 Disorders of fructose metabolism
0.000 0.984 0.016
E74.0 Glycogen storage disease
0.000 0.984 0.016
E85.8 Other amyloidosis
0.000 0.984 0.016
E85.3 Secondary systemic amyloidosis
0.000 0.984 0.016
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.984 0.016
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.984 0.016

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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