TreeWAS – Variant ID: rs10483554

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I67.9 Cerebrovascular disease, unspecified	0.000	0.979	0.021
I67 Other cerebrovascular diseases	0.000	0.984	0.016
I67.1 Cerebral aneurysm, nonruptured	0.000	0.985	0.015
I67.2 Cerebral atherosclerosis	0.000	0.985	0.015
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.987	0.013
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.988	0.012
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.988	0.012
I67.5 Moyamoya disease	0.000	0.988	0.012
I67.4 Hypertensive encephalopathy	0.000	0.988	0.012
I67.3 Progressive vascular leukoencephalopathy	0.000	0.988	0.012
J34.3 Hypertrophy of nasal turbinates	0.010	0.990	0.000
G57.6 Lesion of plantar nerve	0.010	0.990	0.000
G57 Mononeuropathies of lower limb	0.009	0.991	0.000
G57.1 Meralgia paraesthetica	0.009	0.991	0.000
G57.3 Lesion of lateral popliteal nerve	0.008	0.992	0.000
G57.5 Tarsal tunnel syndrome	0.008	0.992	0.000
G57.8 Other mononeuropathies of lower limb	0.008	0.992	0.000
G57.9 Mononeuropathy of lower limb, unspecified	0.007	0.993	0.000
G57.4 Lesion of medial popliteal nerve	0.007	0.993	0.000
G57.2 Lesion of femoral nerve	0.007	0.993	0.000
G57.0 Lesion of sciatic nerve	0.007	0.993	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.000	0.994	0.006
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.006	0.994	0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.005	0.995	0.000
E10.1 With ketoacidosis	0.000	0.995	0.005
O26.8 Other specified pregnancy-related conditions	0.005	0.995	0.000
O62.2 Other uterine inertia	0.005	0.995	0.000
E10.9 Without complications	0.000	0.995	0.005
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.995	0.005
O63.1 Prolonged second stage (of labour)	0.004	0.996	0.000
O62 Abnormalities of forces of labour	0.004	0.996	0.000
I67.8 Other specified cerebrovascular diseases	0.000	0.996	0.004
O63 Long labour	0.004	0.996	0.000
O63.9 Long labour, unspecified	0.004	0.996	0.000
F05.9 Delirium, unspecified	0.000	0.996	0.004
E10 Insulin-dependent diabetes mellitus	0.000	0.996	0.004
K08.2 Atrophy of edentulous alveolar ridge	0.004	0.996	0.000
O62.0 Primary inadequate contractions	0.004	0.996	0.000
O62.1 Secondary uterine inertia	0.004	0.996	0.000
S72.10 Pertrochanteric fracture (closed)	0.004	0.996	0.000
K07.3 Anomalies of tooth position	0.004	0.996	0.000
O62.3 Precipitate labour	0.003	0.996	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.003	0.997	0.000
O62.9 Abnormality of forces of labour, unspecified	0.003	0.997	0.000
O62.8 Other abnormalities of forces of labour	0.003	0.997	0.000
K08 Other disorders of teeth and supporting structures	0.003	0.997	0.000
C71.1 Frontal lobe	0.003	0.997	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.003	0.997	0.000
K09 Cysts of oral region, not elsewhere classified	0.003	0.997	0.000
K02.1 Caries of dentin	0.003	0.997	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.003	0.997	0.000
O63.0 Prolonged first stage (of labour)	0.003	0.997	0.000
K09.0 Developmental odontogenic cysts	0.003	0.997	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.003	0.997	0.000
K61.0 Anal abscess	0.000	0.997	0.003
O60-O75 Complications of labour and delivery	0.003	0.997	0.000
K02 Dental caries	0.003	0.997	0.000
D13.1 Stomach	0.000	0.997	0.003
K07 Dentofacial anomalies [including malocclusion]	0.003	0.997	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.997	0.003
L40.9 Psoriasis, unspecified	0.000	0.997	0.003
E10.6 With other specified complications	0.000	0.997	0.003
O73 Retained placenta and membranes, without haemorrhage	0.003	0.997	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.003	0.997	0.000
O64.1 Obstructed labour due to breech presentation	0.003	0.997	0.000
K09.1 Developmental (nonodontogenic) cysts of oral region	0.003	0.997	0.000
E10.7 With multiple complications	0.000	0.997	0.003
E10.0 With coma	0.000	0.997	0.003
K00 Disorders of tooth development and eruption	0.003	0.997	0.000
K00.6 Disturbances in tooth eruption	0.003	0.997	0.000
O26.0 Excessive weight gain in pregnancy	0.003	0.997	0.000
T82.1 Mechanical complication of cardiac electronic device	0.000	0.997	0.003
Z71.8 Other specified counselling	0.003	0.997	0.000
K09.8 Other cysts of oral region, not elsewhere classified	0.003	0.997	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.997	0.003
K09.2 Other cysts of jaw	0.003	0.997	0.000
C10.9 Oropharynx, unspecified	0.003	0.997	0.000
K02.9 Dental caries, unspecified	0.003	0.997	0.000
E10.2 With renal complications	0.000	0.997	0.003
E10.4 With neurological complications	0.000	0.997	0.003
Z93.3 Colostomy status	0.000	0.997	0.003
O74 Complications of anaesthesia during labour and delivery	0.003	0.997	0.000
E10.8 With unspecified complications	0.000	0.997	0.003
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.003	0.997	0.000
K08.0 Exfoliation of teeth due to systemic causes	0.003	0.997	0.000
K00.0 Anodontia	0.003	0.997	0.000
L08 Other local infections of skin and subcutaneous tissue	0.003	0.997	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O26.5 Maternal hypotension syndrome	0.003	0.997	0.000
O26.4 Herpes gestationis	0.003	0.997	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.003	0.997	0.000
O26.1 Low weight gain in pregnancy	0.003	0.997	0.000
E89.0 Postprocedural hypothyroidism	0.003	0.997	0.000
I69 Sequelae of cerebrovascular disease	0.000	0.997	0.003
E10.5 With peripheral circulatory complications	0.000	0.997	0.003
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.997	0.003
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.000	0.997	0.003
O69 Labour and delivery complicated by umbilical cord complications	0.003	0.997	0.000
O66 Other obstructed labour	0.003	0.997	0.000
I60-I69 Cerebrovascular diseases	0.000	0.997	0.003
I71.0 Dissection of aorta [any part]	0.000	0.997	0.003
K00.9 Disorder of tooth development, unspecified	0.002	0.997	0.000
O60 Preterm delivery	0.002	0.997	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.002	0.997	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.003	0.997	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.997	0.003
K02.5 Caries with pulp exposure	0.002	0.997	0.000
K02.4 Odontoclasia	0.002	0.997	0.000
K02.3 Arrested dental caries	0.002	0.997	0.000
K02.2 Caries of cementum	0.002	0.997	0.000
K02.0 Caries limited to enamel	0.002	0.997	0.000
K07.6 Temporomandibular joint disorders	0.002	0.997	0.000
K09.9 Cyst of oral region, unspecified	0.002	0.997	0.000
K07.9 Dentofacial anomaly, unspecified	0.002	0.997	0.000
K07.8 Other dentofacial anomalies	0.002	0.997	0.000
K07.5 Dentofacial functional abnormalities	0.002	0.997	0.000
K07.2 Anomalies of dental arch relationship	0.002	0.997	0.000
K07.1 Anomalies of jaw-cranial base relationship	0.002	0.997	0.000
K07.0 Major anomalies of jaw size	0.002	0.997	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.002	0.997	0.000
C71.2 Temporal lobe	0.002	0.998	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.998	0.002
K02.8 Other dental caries	0.002	0.998	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.002	0.998	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.000	0.998	0.002
O64.8 Obstructed labour due to other malposition and malpresentation	0.002	0.998	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.000	0.998	0.002
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.998	0.002
I74.5 Embolism and thrombosis of iliac artery	0.000	0.998	0.002
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.002	0.998	0.000
O64.5 Obstructed labour due to compound presentation	0.002	0.998	0.000
O64.4 Obstructed labour due to shoulder presentation	0.002	0.998	0.000
O64.3 Obstructed labour due to brow presentation	0.002	0.998	0.000
O64.2 Obstructed labour due to face presentation	0.002	0.998	0.000
C71 Malignant neoplasm of brain	0.002	0.998	0.000
K10 Other diseases of jaws	0.002	0.998	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.002	0.998	0.000
I60.8 Other subarachnoid haemorrhage	0.000	0.998	0.002
K00.8 Other disorders of tooth development	0.002	0.998	0.000
K00.7 Teething syndrome	0.002	0.998	0.000
K00.5 Hereditary disturbances in tooth structure, not elsewhere classified	0.002	0.998	0.000
K00.4 Disturbances in tooth formation	0.002	0.998	0.000
K00.3 Mottled teeth	0.002	0.998	0.000
K00.2 Abnormalities of size and form of teeth	0.002	0.998	0.000
K00.1 Supernumerary teeth	0.002	0.998	0.000
K07.4 Malocclusion, unspecified	0.002	0.998	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.998	0.002
O75.8 Other specified complications of labour and delivery	0.002	0.998	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.002	0.998	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.002	0.998	0.000
O26.2 Pregnancy care of habitual aborter	0.002	0.998	0.000
T82.3 Mechanical complication of other vascular grafts	0.000	0.998	0.002
T82.4 Mechanical complication of vascular dialysis catheter	0.000	0.998	0.002
O75 Other complications of labour and delivery, not elsewhere classified	0.002	0.998	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.002	0.998	0.000
H61.8 Other specified disorders of external ear	0.000	0.998	0.002
L08.8 Other specified local infections of skin and subcutaneous tissue	0.002	0.998	0.000
O26.9 Pregnancy-related condition, unspecified	0.002	0.998	0.000
I71 Aortic aneurysm and dissection	0.000	0.998	0.002
O24 Diabetes mellitus in pregnancy	0.002	0.998	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.002	0.998	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.002	0.998	0.000
K10.2 Inflammatory conditions of jaws	0.002	0.998	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.002	0.998	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.002	0.998	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.000	0.998	0.002
J34 Other disorders of nose and nasal sinuses	0.002	0.998	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.002	0.998	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.002	0.998	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.002	0.998	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.002	0.998	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.002	0.998	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.002	0.998	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.002	0.998	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.002	0.998	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.002	0.998	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.002	0.998	0.000
K10.9 Disease of jaws, unspecified	0.002	0.998	0.000
K03 Other diseases of hard tissues of teeth	0.002	0.998	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.998	0.002
L08.1 Erythrasma	0.002	0.998	0.000
L08.0 Pyoderma	0.002	0.998	0.000
S72.1 Pertrochanteric fracture	0.002	0.998	0.000
E10.3 With ophthalmic complications	0.000	0.998	0.002
K08.8 Other specified disorders of teeth and supporting structures	0.002	0.998	0.000
O82.9 Delivery by Caesarean section, unspecified	0.002	0.998	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.000	0.998	0.002
R74.8 Abnormal levels of other serum enzymes	0.002	0.998	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.000	0.998	0.002
O21 Excessive vomiting in pregnancy	0.002	0.998	0.000
O72 Postpartum haemorrhage	0.002	0.998	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.002	0.998	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.998	0.002
I62 Other nontraumatic intracranial haemorrhage	0.000	0.998	0.002
O23 Infections of genito-urinary tract in pregnancy	0.002	0.998	0.000
I33.0 Acute and subacute infective endocarditis	0.000	0.998	0.002
O75.0 Maternal distress during labour and delivery	0.002	0.998	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.000	0.998	0.002
I74 Arterial embolism and thrombosis	0.000	0.998	0.002
O61 Failed induction of labour	0.002	0.998	0.000
O73.0 Retained placenta, without haemorrhage	0.002	0.998	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.002	0.998	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.998	0.002
J43.9 Emphysema, unspecified	0.000	0.998	0.002
O66.9 Obstructed labour, unspecified	0.002	0.998	0.000
O66.8 Other specified obstructed labour	0.002	0.998	0.000
O66.4 Failed trial of labour, unspecified	0.002	0.998	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.002	0.998	0.000
O66.2 Obstructed labour due to unusually large foetus	0.002	0.998	0.000
O66.1 Obstructed labour due to locked twins	0.002	0.998	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.002	0.998	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.002	0.998	0.000
O69.3 Labour and delivery complicated by short cord	0.002	0.998	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.998	0.002
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.998	0.002
I60 Subarachnoid haemorrhage	0.000	0.998	0.002
I69.3 Sequelae of cerebral infarction	0.000	0.998	0.002
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.000	0.998	0.002
K14 Diseases of tongue	0.002	0.998	0.000
O60.3 Preterm delivery without spontaneous labour	0.002	0.998	0.000
O60.2 Preterm spontaneous labour with term delivery	0.002	0.998	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.002	0.998	0.000
O60.0 Preterm labour without delivery	0.002	0.998	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.002	0.998	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.002	0.998	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.002	0.998	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.002	0.998	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.002	0.998	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.002	0.998	0.000
O65.0 Obstructed labour due to deformed pelvis	0.002	0.998	0.000
C10 Malignant neoplasm of oropharynx	0.002	0.998	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.002	0.998	0.000
O29 Complications of anaesthesia during pregnancy	0.002	0.998	0.000
O22 Venous complications in pregnancy	0.002	0.998	0.000
O25 Malnutrition in pregnancy	0.002	0.998	0.000
J34.1 Cyst and mucocele of nose and nasal sinus	0.002	0.998	0.000
M17.9 Gonarthrosis, unspecified	0.002	0.998	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.998	0.002
K08.9 Disorder of teeth and supporting structures, unspecified	0.002	0.998	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.002	0.998	0.000
C71.7 Brain stem	0.002	0.998	0.000
C71.6 Cerebellum	0.002	0.998	0.000
C71.5 Cerebral ventricle	0.002	0.998	0.000
K10.3 Alveolitis of jaws	0.002	0.998	0.000
K10.1 Giant cell granuloma, central	0.002	0.998	0.000
C71.4 Occipital lobe	0.002	0.998	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.998	0.002
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.002	0.998	0.000
O71 Other obstetric trauma	0.002	0.998	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.002	0.998	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.998	0.002
N18.5 Chronic kidney disease, stage 5	0.000	0.998	0.002
F31 Bipolar affective disorder	0.000	0.998	0.002
K06 Other disorders of gingiva and edentulous alveolar ridge	0.002	0.998	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.998	0.002
K10.0 Developmental disorders of jaws	0.002	0.998	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.002	0.998	0.000
C71.8 Overlapping lesion of brain	0.002	0.998	0.000
K14.0 Glossitis	0.002	0.998	0.000
O75.9 Complication of labour and delivery, unspecified	0.002	0.998	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.002	0.998	0.000
O75.4 Other complications of obstetric surgery and procedures	0.002	0.998	0.000
O75.3 Other infection during labour	0.002	0.998	0.000
O75.1 Shock during or following labour and delivery	0.002	0.998	0.000
C71.0 Cerebrum, except lobes and ventricles	0.002	0.998	0.000
D48.1 Connective and other soft tissue	0.002	0.998	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.998	0.002
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.998	0.002
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.998	0.002
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.998	0.002
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified	0.002	0.998	0.000
O28 Abnormal findings on antenatal screening of mother	0.002	0.998	0.000
C71.9 Brain, unspecified	0.002	0.998	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.998	0.002
O21.0 Mild hyperemesis gravidarum	0.002	0.998	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.002	0.998	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.002	0.998	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.002	0.998	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.002	0.998	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.002	0.998	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.002	0.998	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.998	0.002
O03.4 Incomplete, without complication	0.002	0.998	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.002	0.998	0.000
I63.9 Cerebral infarction, unspecified	0.000	0.998	0.002
L40.0 Psoriasis vulgaris	0.000	0.998	0.002
O69.1 Labour and delivery complicated by cord around neck, with compression	0.002	0.998	0.000
O82.1 Delivery by emergency Caesarean section	0.002	0.998	0.000
O70 Perineal laceration during delivery	0.002	0.998	0.000
L40 Psoriasis	0.000	0.998	0.002
O20 Haemorrhage in early pregnancy	0.002	0.998	0.000
K03.9 Disease of hard tissues of teeth, unspecified	0.002	0.998	0.000
K03.8 Other specified diseases of hard tissues of teeth	0.002	0.998	0.000
K03.7 Posteruptive colour changes of dental hard tissues	0.002	0.998	0.000
K03.6 Deposits [accretions] on teeth	0.002	0.998	0.000
K03.5 Ankylosis of teeth	0.002	0.998	0.000
K03.4 Hypercementosis	0.002	0.998	0.000
K03.3 Pathological resorption of teeth	0.002	0.998	0.000
K03.2 Erosion of teeth	0.002	0.998	0.000
K03.1 Abrasion of teeth	0.002	0.998	0.000
K03.0 Excessive attrition of teeth	0.002	0.998	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.002	0.998	0.000
S72.11 Pertrochanteric fracture (open)	0.002	0.998	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.998	0.002
O20.8 Other haemorrhage in early pregnancy	0.002	0.998	0.000
O69.8 Labour and delivery complicated by other cord complications	0.002	0.998	0.000
O21.8 Other vomiting complicating pregnancy	0.002	0.998	0.000
O21.2 Late vomiting of pregnancy	0.002	0.998	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.002	0.998	0.000
O67.8 Other intrapartum haemorrhage	0.002	0.998	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.002	0.998	0.000
O72.3 Postpartum coagulation defects	0.002	0.998	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.002	0.998	0.000
R47.1 Dysarthria and anarthria	0.000	0.998	0.002
I62.1 Nontraumatic extradural haemorrhage	0.000	0.998	0.002
O23.3 Infections of other parts of urinary tract in pregnancy	0.002	0.998	0.000
O23.2 Infections of urethra in pregnancy	0.002	0.998	0.000
O23.1 Infections of bladder in pregnancy	0.002	0.998	0.000
O23.0 Infections of kidney in pregnancy	0.002	0.998	0.000
O61.9 Failed induction of labour, unspecified	0.001	0.998	0.000
O61.8 Other failed induction of labour	0.001	0.998	0.000
O61.1 Failed instrumental induction of labour	0.001	0.998	0.000
C71.3 Parietal lobe	0.002	0.998	0.000
F05.1 Delirium superimposed on dementia	0.000	0.998	0.002
F05.0 Delirium not superimposed on dementia, so described	0.000	0.998	0.002
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.998	0.002
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.998	0.002
O21.9 Vomiting of pregnancy, unspecified	0.002	0.998	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.998	0.002
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.998	0.002
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.998	0.002
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.998	0.002
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.998	0.002
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.998	0.002
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.998	0.002
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.998	0.002
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.998	0.002
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.998	0.002
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.998	0.002
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.998	0.002
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
I68.0 Cerebral amyloid angiopathy	0.000	0.998	0.002
H53.1 Subjective visual disturbances	0.002	0.998	0.000
H60.1 Cellulitis of external ear	0.000	0.998	0.002
J34.0 Abscess, furuncle and carbuncle of nose	0.002	0.998	0.000
K14.6 Glossodynia	0.002	0.998	0.000
K14.5 Plicated tongue	0.002	0.998	0.000
K14.4 Atrophy of tongue papillae	0.002	0.998	0.000
K14.3 Hypertrophy of tongue papillae	0.002	0.998	0.000
K14.2 Median rhomboid glossitis	0.002	0.998	0.000
K14.1 Geographic tongue	0.002	0.998	0.000
O70.2 Third degree perineal laceration during delivery	0.002	0.998	0.000
C10.8 Overlapping lesion of oropharynx	0.002	0.998	0.000
C10.4 Branchial cleft	0.002	0.998	0.000
C10.3 Posterior wall of oropharynx	0.002	0.998	0.000
C10.2 Lateral wall of oropharynx	0.002	0.998	0.000
C10.1 Anterior surface of epiglottis	0.002	0.998	0.000
C10.0 Vallecula	0.002	0.998	0.000
O22.9 Venous complication in pregnancy, unspecified	0.002	0.998	0.000
O22.8 Other venous complications in pregnancy	0.002	0.998	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.002	0.998	0.000
O22.4 Haemorrhoids in pregnancy	0.002	0.998	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.002	0.998	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.002	0.998	0.000
O22.1 Genital varices in pregnancy	0.002	0.998	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.002	0.998	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.002	0.998	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.002	0.998	0.000
O29.6 Failed or difficult intubation during pregnancy	0.002	0.998	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.002	0.998	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.002	0.998	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.002	0.998	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.002	0.998	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.002	0.998	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.002	0.998	0.000
M84 Disorders of continuity of bone	0.002	0.998	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.998	0.002
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.998	0.002
O75.2 Pyrexia during labour, not elsewhere classified	0.002	0.998	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.998	0.002
I63 Cerebral infarction	0.000	0.998	0.002
K01 Embedded and impacted teeth	0.002	0.998	0.000
O82 Single delivery by Caesarean section	0.002	0.998	0.000
M84.26 Delayed union of fracture (Lower leg)	0.002	0.998	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.998	0.002
M84.2 Delayed union of fracture	0.002	0.998	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.998	0.002
K10.8 Other specified diseases of jaws	0.002	0.998	0.000
O71.9 Obstetric trauma, unspecified	0.001	0.998	0.000
O71.7 Obstetric haematoma of pelvis	0.001	0.998	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.001	0.998	0.000
O71.5 Other obstetric injury to pelvic organs	0.001	0.998	0.000
O71.3 Obstetric laceration of cervix	0.001	0.998	0.000
O71.2 Postpartum inversion of uterus	0.001	0.998	0.000
O71.1 Rupture of uterus during labour	0.001	0.998	0.000
O71.0 Rupture of uterus before onset of labour	0.001	0.998	0.000
H60 Otitis externa	0.000	0.998	0.002
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.002	0.998	0.000
F31.8 Other bipolar affective disorders	0.000	0.998	0.002
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.998	0.002
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.998	0.002
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.998	0.002
I74.8 Embolism and thrombosis of other arteries	0.000	0.998	0.002
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma	0.001	0.998	0.000
K06.0 Gingival recession	0.001	0.998	0.000
K05 Gingivitis and periodontal diseases	0.002	0.998	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.002	0.998	0.000
D10.3 Other and unspecified parts of mouth	0.000	0.998	0.002
H60.9 Otitis externa, unspecified	0.000	0.998	0.002
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.001	0.998	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.001	0.998	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.001	0.998	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.001	0.998	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.001	0.998	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.001	0.998	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.001	0.998	0.000
Z99.2 Dependence on renal dialysis	0.000	0.998	0.002
Q28 Other congenital malformations of circulatory system	0.000	0.998	0.002
F05.8 Other delirium	0.000	0.998	0.001
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.998	0.002
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.001	0.998	0.000
Q23.1 Congenital insufficiency of aortic valve	0.000	0.998	0.002
O03 Spontaneous abortion	0.002	0.998	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.998	0.001
L27.0 Generalised skin eruption due to drugs and medicaments	0.000	0.998	0.002
O70.3 Fourth degree perineal laceration during delivery	0.002	0.998	0.000
O72.0 Third-stage haemorrhage	0.002	0.998	0.000
F31.7 Bipolar affective disorder, currently in remission	0.000	0.998	0.001
H60.8 Other otitis externa	0.000	0.998	0.002
K06.1 Gingival enlargement	0.001	0.998	0.000
L40.4 Guttate psoriasis	0.000	0.998	0.001
L40.3 Pustulosis palmaris et plantaris	0.000	0.998	0.001
L40.2 Acrodermatitis continua	0.000	0.998	0.001
L40.1 Generalised pustular psoriasis	0.000	0.998	0.001
M84.8 Other disorders of continuity of bone	0.002	0.998	0.000
C11.9 Nasopharynx, unspecified	0.002	0.998	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.998	0.002
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.998	0.001
M84.0 Malunion of fracture	0.002	0.998	0.000
O61.0 Failed medical induction of labour	0.001	0.998	0.001
C01 Malignant neoplasm of base of tongue	0.002	0.998	0.000
M84.02 Malunion of fracture (Upper arm)	0.002	0.998	0.000
H60.3 Other infective otitis externa	0.000	0.998	0.002
K13.5 Oral submucous fibrosis	0.002	0.998	0.000
R47.0 Dysphasia and aphasia	0.000	0.998	0.002
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.000	0.998	0.002
Z99.8 Dependence on other enabling machines and devices	0.000	0.998	0.002
E89.3 Postprocedural hypopituitarism	0.002	0.998	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.998	0.001
O70.9 Perineal laceration during delivery, unspecified	0.002	0.998	0.000
O71.8 Other specified obstetric trauma	0.001	0.998	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.001	0.998	0.000
J34.8 Other specified disorders of nose and nasal sinuses	0.002	0.998	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.002	0.998	0.000
K14.9 Disease of tongue, unspecified	0.002	0.998	0.000
O70.0 First degree perineal laceration during delivery	0.002	0.998	0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.001	0.998	0.000
Q27.3 Peripheral arteriovenous malformation	0.000	0.998	0.001
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.001	0.998	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.998	0.001
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.998	0.001
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.998	0.001
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.998	0.001
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.998	0.001
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.998	0.001
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.998	0.001
I65.1 Occlusion and stenosis of basilar artery	0.000	0.998	0.001
M84.9 Disorder of continuity of bone, unspecified	0.001	0.998	0.000
M84.3 Stress fracture, not elsewhere classified	0.001	0.998	0.000
O82.8 Other single delivery by Caesarean section	0.001	0.998	0.000
O82.2 Delivery by Caesarean hysterectomy	0.001	0.998	0.000
C11 Malignant neoplasm of nasopharynx	0.001	0.998	0.000
K13 Other diseases of lip and oral mucosa	0.002	0.998	0.000
M84.01 Malunion of fracture (Shoulder region)	0.001	0.998	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.001	0.998	0.000
M84.28 Delayed union of fracture (Other)	0.001	0.998	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.001	0.998	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.001	0.998	0.000
M84.24 Delayed union of fracture (Hand)	0.001	0.998	0.000
M84.23 Delayed union of fracture (Forearm)	0.001	0.998	0.000
M84.22 Delayed union of fracture (Upper arm)	0.001	0.998	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.001	0.998	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.001	0.998	0.000
H60.4 Cholesteatoma of external ear	0.000	0.998	0.001
H60.2 Malignant otitis externa	0.000	0.998	0.001
H60.0 Abscess of external ear	0.000	0.998	0.001
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.998	0.001
L40.5 Arthropathic psoriasis	0.000	0.998	0.002
M84.4 Pathological fracture, not elsewhere classified	0.001	0.998	0.000
O23.5 Infections of the genital tract in pregnancy	0.001	0.998	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.001	0.998	0.000
K12 Stomatitis and related lesions	0.001	0.998	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.998	0.001
K01.0 Embedded teeth	0.001	0.998	0.000
K11.7 Disturbances of salivary secretion	0.001	0.998	0.000
L40.8 Other psoriasis	0.000	0.998	0.001
O67.9 Intrapartum haemorrhage, unspecified	0.001	0.998	0.000
O72.1 Other immediate postpartum haemorrhage	0.002	0.998	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.001	0.998	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations