TreeWAS – Variant ID: rs10506621

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I35.2 Aortic (valve) stenosis with insufficiency	0.047	0.953	0.000
I35 Nonrheumatic aortic valve disorders	0.045	0.955	0.000
I35.8 Other aortic valve disorders	0.045	0.955	0.000
I35.1 Aortic (valve) insufficiency	0.040	0.960	0.000
I35.0 Aortic (valve) stenosis	0.039	0.961	0.000
Z42.1 Follow-up care involving plastic surgery of breast	0.000	0.969	0.031
I35.9 Aortic valve disorder, unspecified	0.028	0.972	0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.023	0.977	0.000
N83.2 Other and unspecified ovarian cysts	0.022	0.978	0.000
N83.0 Follicular cyst of ovary	0.022	0.978	0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.021	0.979	0.000
N83.3 Acquired atrophy of ovary and Fallopian tube	0.020	0.980	0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube	0.020	0.980	0.000
Z42 Follow-up care involving plastic surgery	0.000	0.981	0.019
N83.6 Haematosalpinx	0.017	0.983	0.000
N83.7 Haematoma of broad ligament	0.016	0.983	0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube	0.016	0.983	0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.000	0.984	0.016
N89.8 Other specified noninflammatory disorders of vagina	0.015	0.985	0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.000	0.985	0.015
Z42.9 Follow-up care involving plastic surgery, unspecified	0.000	0.986	0.014
Z42.8 Follow-up care involving plastic surgery of other body part	0.000	0.986	0.014
N83.1 Corpus luteum cyst	0.014	0.986	0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity	0.000	0.987	0.013
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.013	0.987	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.000	0.988	0.012
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified	0.011	0.989	0.000
F41 Other anxiety disorders	0.009	0.991	0.000
F41.1 Generalised anxiety disorder	0.007	0.992	0.000
F43 Reaction to severe stress, and adjustment disorders	0.007	0.993	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.007	0.993	0.000
F41.8 Other specified anxiety disorders	0.007	0.993	0.000
F41.3 Other mixed anxiety disorders	0.006	0.993	0.000
F43.1 Posttraumatic stress disorder	0.006	0.994	0.000
F42 Obsessive-compulsive disorder	0.006	0.994	0.000
F41.9 Anxiety disorder, unspecified	0.006	0.994	0.000
F43.2 Adjustment disorders	0.006	0.994	0.000
F43.9 Reaction to severe stress, unspecified	0.006	0.994	0.000
F43.0 Acute stress reaction	0.006	0.994	0.000
F48 Other neurotic disorders	0.006	0.994	0.000
F42.9 Obsessive-compulsive disorder, unspecified	0.006	0.994	0.000
G93.3 Postviral fatigue syndrome	0.006	0.994	0.000
F44 Dissociative [conversion] disorders	0.005	0.995	0.000
F43.8 Other reactions to severe stress	0.005	0.995	0.000
N89 Other noninflammatory disorders of vagina	0.005	0.995	0.000
F45 Somatoform disorders	0.005	0.995	0.000
F42.0 Predominantly obsessional thoughts or ruminations	0.005	0.995	0.000
F42.8 Other obsessive-compulsive disorders	0.005	0.995	0.000
F42.2 Mixed obsessional thoughts and acts	0.005	0.995	0.000
F42.1 Predominantly compulsive acts [obsessional rituals]	0.005	0.995	0.000
F45.3 Somatoform autonomic dysfunction	0.005	0.995	0.000
J43.9 Emphysema, unspecified	0.005	0.995	0.000
F48.9 Neurotic disorder, unspecified	0.004	0.995	0.000
N89.5 Stricture and atresia of vagina	0.005	0.995	0.000
J95.8 Other postprocedural respiratory disorders	0.000	0.996	0.004
F44.9 Dissociative [conversion] disorder, unspecified	0.004	0.996	0.000
F48.8 Other specified neurotic disorders	0.004	0.996	0.000
F48.1 Depersonalisation-derealisation syndrome	0.004	0.996	0.000
G63.2 Diabetic polyneuropathy	0.004	0.996	0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.004	0.996	0.000
F48.0 Neurasthenia	0.004	0.996	0.000
F44.8 Other dissociative [conversion] disorders	0.004	0.996	0.000
F44.7 Mixed dissociative [conversion] disorders	0.004	0.996	0.000
F44.6 Dissociative anaesthesia and sensory loss	0.004	0.996	0.000
F44.5 Dissociative convulsions	0.004	0.996	0.000
F44.3 Trance and possession disorders	0.004	0.996	0.000
F44.2 Dissociative stupor	0.004	0.996	0.000
F44.1 Dissociative fugue	0.004	0.996	0.000
F44.0 Dissociative amnesia	0.004	0.996	0.000
S42.00 Fracture of clavicle (closed)	0.004	0.996	0.000
F40 Phobic anxiety disorders	0.004	0.996	0.000
F44.4 Dissociative motor disorders	0.004	0.996	0.000
N89.7 Haematocolpos	0.004	0.996	0.000
N89.4 Leukoplakia of vagina	0.004	0.996	0.000
N89.3 Dysplasia of vagina, unspecified	0.004	0.996	0.000
N89.2 Severe vaginal dysplasia, not elsewhere classified	0.004	0.996	0.000
N89.1 Moderate vaginal dysplasia	0.004	0.996	0.000
N89.0 Mild vaginal dysplasia	0.004	0.996	0.000
F45.4 Persistent somatoform pain disorder	0.004	0.996	0.000
F45.2 Hypochondriacal disorder	0.004	0.996	0.000
F45.1 Undifferentiated somatoform disorder	0.004	0.996	0.000
F45.0 Somatisation disorder	0.004	0.996	0.000
F45.9 Somatoform disorder, unspecified	0.004	0.996	0.000
G93.4 Encephalopathy, unspecified	0.004	0.996	0.000
N89.9 Noninflammatory disorder of vagina, unspecified	0.004	0.996	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.004	0.996	0.000
F33 Recurrent depressive disorder	0.003	0.997	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.997	0.003
S82.00 Fracture of patella (closed)	0.000	0.997	0.003
F40.9 Phobic anxiety disorder, unspecified	0.003	0.997	0.000
F40.8 Other phobic anxiety disorders	0.003	0.997	0.000
F40.1 Social phobias	0.003	0.997	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.003	0.997	0.000
Q61.2 Polycystic kidney, adult type	0.000	0.997	0.003
C19 Malignant neoplasm of rectosigmoid junction	0.003	0.997	0.000
W25.9 Unspecified place	0.003	0.997	0.000
F33.9 Recurrent depressive disorder, unspecified	0.003	0.997	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.997	0.003
G93 Other disorders of brain	0.003	0.997	0.000
S43.0 Dislocation of shoulder joint	0.000	0.997	0.003
C26.0 Intestinal tract, part unspecified	0.003	0.997	0.000
G93.5 Compression of brain	0.003	0.997	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.003	0.997	0.000
F40.0 Agoraphobia	0.003	0.997	0.000
N88.2 Stricture and stenosis of cervix uteri	0.003	0.997	0.000
Q61.3 Polycystic kidney, unspecified	0.000	0.997	0.003
T79.7 Traumatic subcutaneous emphysema	0.003	0.997	0.000
C25 Malignant neoplasm of pancreas	0.003	0.997	0.000
N89.6 Tight hymenal ring	0.002	0.997	0.000
C25.9 Pancreas, unspecified	0.003	0.997	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.003	0.997	0.000
C20 Malignant neoplasm of rectum	0.003	0.997	0.000
F33.8 Other recurrent depressive disorders	0.003	0.997	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.003	0.997	0.000
O04.9 Complete or unspecified, without complication	0.003	0.997	0.000
C25.3 Pancreatic duct	0.003	0.997	0.000
C15-C26 Malignant neoplasms of digestive organs	0.003	0.997	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.003	0.997	0.000
Q89.2 Congenital malformations of other endocrine glands	0.003	0.997	0.000
C17.1 Jejunum	0.003	0.997	0.000
C17 Malignant neoplasm of small intestine	0.003	0.997	0.000
Q61 Cystic kidney disease	0.000	0.997	0.003
K51.9 Ulcerative colitis, unspecified	0.000	0.997	0.003
G93.2 Benign intracranial hypertension	0.003	0.997	0.000
C25.2 Tail of pancreas	0.002	0.997	0.000
C25.1 Body of pancreas	0.002	0.997	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.002	0.997	0.000
T46.1 Calcium-channel blockers	0.002	0.997	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.002	0.998	0.000
G93.7 Reye's syndrome	0.002	0.998	0.000
M77.12 Lateral epicondylitis (Upper arm)	0.002	0.998	0.000
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.002	0.998	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.002	0.998	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.998	0.002
G93.0 Cerebral cysts	0.002	0.998	0.000
Q61.5 Medullary cystic kidney	0.000	0.998	0.002
T42.4 Benzodiazepines	0.002	0.998	0.000
C25.8 Overlapping lesion of pancreas	0.002	0.998	0.000
C25.7 Other parts of pancreas	0.002	0.998	0.000
C25.4 Endocrine pancreas	0.002	0.998	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.998	0.002
F41.2 Mixed anxiety and depressive disorder	0.002	0.998	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.002	0.998	0.000
G93.6 Cerebral oedema	0.002	0.998	0.000
F45.8 Other somatoform disorders	0.002	0.998	0.000
C26.8 Overlapping lesion of digestive system	0.002	0.998	0.000
C26.1 Spleen	0.002	0.998	0.000
F40.2 Specific (isolated) phobias	0.002	0.998	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.000	0.998	0.002
C17.9 Small intestine, unspecified	0.002	0.998	0.000
F31.9 Bipolar affective disorder, unspecified	0.002	0.998	0.000
S42.0 Fracture of clavicle	0.002	0.998	0.000
C17.0 Duodenum	0.002	0.998	0.000
Q89 Other congenital malformations, not elsewhere classified	0.002	0.998	0.000
C24.0 Extrahepatic bile duct	0.002	0.998	0.000
F31 Bipolar affective disorder	0.002	0.998	0.000
C17.8 Overlapping lesion of small intestine	0.002	0.998	0.000
C17.3 Meckel's diverticulum	0.002	0.998	0.000
Q61.8 Other cystic kidney diseases	0.000	0.998	0.002
Q61.1 Polycystic kidney, infantile type	0.000	0.998	0.002
F30-F39 Mood [affective] disorders	0.002	0.998	0.000
C26.9 Ill-defined sites within the digestive system	0.002	0.998	0.000
N49.2 Inflammatory disorders of scrotum	0.002	0.998	0.000
C18.2 Ascending colon	0.002	0.998	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.002	0.998	0.000
R73.9 Hyperglycaemia, unspecified	0.000	0.998	0.002
G63 Polyneuropathy in diseases classified elsewhere	0.002	0.998	0.000
M47.89 Other spondylosis (Site unspecified)	0.000	0.998	0.002
T79.5 Traumatic anuria	0.002	0.998	0.000
C24.9 Biliary tract, unspecified	0.002	0.998	0.000
F31.7 Bipolar affective disorder, currently in remission	0.002	0.998	0.000
Q61.9 Cystic kidney disease, unspecified	0.000	0.998	0.002
Q85 Phakomatoses, not elsewhere classified	0.002	0.998	0.000
C24.8 Overlapping lesion of biliary tract	0.002	0.998	0.000
Q61.4 Renal dysplasia	0.000	0.998	0.002
C17.2 Ileum	0.002	0.998	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.002	0.998	0.000
C23 Malignant neoplasm of gallbladder	0.002	0.998	0.000
O04 Medical abortion	0.002	0.998	0.000
W25 Contact with sharp glass	0.002	0.998	0.000
T79.8 Other early complications of trauma	0.002	0.998	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.002	0.998	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.002	0.998	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.002	0.998	0.000
M95.0 Acquired deformity of nose	0.002	0.998	0.000
O04.4 Incomplete, without complication	0.002	0.998	0.000
T79.9 Unspecified early complication of trauma	0.002	0.998	0.000
T79.4 Traumatic shock	0.002	0.998	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.002	0.998	0.000
T79.1 Fat embolism (traumatic)	0.002	0.998	0.000
T79.0 Air embolism (traumatic)	0.002	0.998	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.998	0.002
G93.1 Anoxic brain damage, not elsewhere classified	0.002	0.998	0.000
C21 Malignant neoplasm of anus and anal canal	0.002	0.998	0.000
J43 Emphysema	0.002	0.998	0.000
I15.1 Hypertension secondary to other renal disorders	0.000	0.998	0.002
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.002	0.998	0.000
S42.01 Fracture of clavicle (open)	0.002	0.998	0.000
C18.4 Transverse colon	0.002	0.998	0.000
C80.9 Malignant neoplasm, unspecified	0.000	0.998	0.002
O04.8 Complete or unspecified, with other and unspecified complications	0.002	0.998	0.000
T50.4 Drugs affecting uric acid metabolism	0.002	0.998	0.000
C24.1 Ampulla of Vater	0.002	0.998	0.000
Q89.9 Congenital malformation, unspecified	0.002	0.998	0.000
Q89.8 Other specified congenital malformations	0.002	0.998	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.002	0.998	0.000
Q89.4 Conjoined twins	0.002	0.998	0.000
Q89.3 Situs inversus	0.002	0.998	0.000
Q89.1 Congenital malformations of adrenal gland	0.002	0.998	0.000
Q89.0 Congenital malformations of spleen	0.002	0.998	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
C16 Malignant neoplasm of stomach	0.002	0.998	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
F31.8 Other bipolar affective disorders	0.002	0.998	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.998	0.002
Q80-Q89 Other congenital malformations	0.002	0.998	0.000
S22.50 Flail chest (closed)	0.002	0.998	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.000	0.998	0.002
C80 Malignant neoplasm without specification of site	0.000	0.998	0.002
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.998	0.002
C18.0 Caecum	0.002	0.998	0.000
G93.9 Disorder of brain, unspecified	0.002	0.998	0.000
I42.9 Cardiomyopathy, unspecified	0.000	0.998	0.002
Q61.0 Congenital single renal cyst	0.000	0.998	0.002
F38 Other mood [affective] disorders	0.002	0.998	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.000	0.998	0.002
C18 Malignant neoplasm of colon	0.002	0.998	0.000
U89.8 Agent resistant to other single specified antibiotic	0.002	0.998	0.000
W25.8 Other specified place	0.002	0.998	0.000
F39 Unspecified mood [affective] disorder	0.002	0.998	0.000
C16.6 Greater curvature of stomach, unspecified	0.002	0.998	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.002	0.998	0.000
G63.6 Polyneuropathy in other musculoskeletal disorders	0.002	0.998	0.000
G63.5 Polyneuropathy in systemic connective tissue disorders	0.002	0.998	0.000
G63.4 Polyneuropathy in nutritional deficiency	0.002	0.998	0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.002	0.998	0.000
G63.1 Polyneuropathy in neoplastic disease	0.002	0.998	0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.000	0.998	0.002
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.998	0.002
Q85.9 Phakomatosis, unspecified	0.002	0.998	0.000
T50.8 Diagnostic agents	0.002	0.998	0.000
C16.1 Fundus of stomach	0.002	0.998	0.000
C49.1 Connective and soft tissue of upper limb, including shoulder	0.002	0.998	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.000	0.998	0.002
C15 Malignant neoplasm of oesophagus	0.002	0.998	0.000
Q85.1 Tuberous sclerosis	0.002	0.998	0.000
I42.2 Other hypertrophic cardiomyopathy	0.000	0.998	0.002
K51.4 Pseudopolyposis of colon	0.000	0.998	0.002
O04.7 Complete or unspecified, complicated by embolism	0.002	0.998	0.000
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.002	0.998	0.000
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.002	0.998	0.000
O04.3 Incomplete, with other and unspecified complications	0.002	0.998	0.000
O04.2 Incomplete, complicated by embolism	0.002	0.998	0.000
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.002	0.998	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.002	0.998	0.000
W25.6 Industrial and construction area	0.002	0.998	0.000
W25.5 Trade and service area	0.002	0.998	0.000
W25.1 Residential institution	0.002	0.998	0.000
W25.0 Home	0.002	0.998	0.000
W25.7 Farm	0.002	0.998	0.000
W25.4 Street and highway	0.002	0.998	0.000
W25.3 Sports and athletics area	0.002	0.998	0.000
W25.2 School, other institution and public administrative area	0.002	0.998	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.002	0.998	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.002	0.998	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.998	0.002
Q83.1 Accessory breast	0.002	0.998	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.002	0.998	0.000
F30 Manic episode	0.002	0.998	0.000
Q83 Congenital malformations of breast	0.002	0.998	0.000
C16.9 Stomach, unspecified	0.002	0.998	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.002	0.998	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.000	0.998	0.002
C18.1 Appendix	0.002	0.998	0.000
C21.2 Cloacogenic zone	0.001	0.998	0.000
G80.9 Infantile cerebral palsy, unspecified	0.002	0.998	0.000
J43.8 Other emphysema	0.001	0.998	0.000
J43.1 Panlobular emphysema	0.001	0.998	0.000
J43.0 MacLeod's syndrome	0.001	0.998	0.000
S82.0 Fracture of patella	0.000	0.998	0.002
Z58.1 Exposure to air pollution	0.002	0.998	0.000
Q60-Q64 Congenital malformations of the urinary system	0.000	0.998	0.001
S22.40 Multiple fractures of ribs (closed)	0.002	0.998	0.000
C15.4 Middle third of oesophagus	0.002	0.998	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.001	0.998	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.001	0.998	0.000
T42.3 Barbiturates	0.001	0.998	0.000
T42.2 Succinimides and oxazolidinediones	0.001	0.998	0.000
T42.0 Hydantoin derivatives	0.001	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
K51 Ulcerative colitis	0.000	0.998	0.002
C16.8 Overlapping lesion of stomach	0.001	0.998	0.000
C16.4 Pylorus	0.001	0.998	0.000
C18.8 Overlapping lesion of colon	0.002	0.998	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.002	0.998	0.000
Q24.8 Other specified congenital malformations of heart	0.002	0.998	0.000
T50.7 Analeptics and opioid receptor antagonists	0.001	0.998	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.001	0.998	0.000
T50.5 Appetite depressants	0.001	0.998	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.001	0.998	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.001	0.998	0.000
T50.1 Loop [high-ceiling] diuretics	0.001	0.998	0.000
T50.0 Mineralocorticoids and their antagonists	0.001	0.998	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.000	0.998	0.002
F34 Persistent mood [affective] disorders	0.001	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.002	0.998	0.000
T42.1 Iminostilbenes	0.001	0.998	0.000
T78.4 Allergy, unspecified	0.002	0.998	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.001	0.998	0.000
Q84 Other congenital malformations of integument	0.001	0.998	0.000
Q81 Epidermolysis bullosa	0.001	0.998	0.000
Q80 Congenital ichthyosis	0.001	0.998	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.000	0.998	0.002
C25.0 Head of pancreas	0.001	0.998	0.000
F38.8 Other specified mood [affective] disorders	0.001	0.998	0.000
F38.1 Other recurrent mood [affective] disorders	0.001	0.998	0.000
F38.0 Other single mood [affective] disorders	0.001	0.998	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.001	0.998	0.000
K51.2 Ulcerative (chronic) proctitis	0.000	0.998	0.002
Q82 Other congenital malformations of skin	0.001	0.998	0.000
S82.01 Fracture of patella (open)	0.000	0.998	0.001
S22.5 Flail chest	0.001	0.998	0.000
Q63 Other congenital malformations of kidney	0.000	0.998	0.001
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.001	0.998	0.000
J95.5 Postprocedural subglottic stenosis	0.000	0.998	0.001
J95.4 Mendelson's syndrome	0.000	0.998	0.001
J95.3 Chronic pulmonary insufficiency following surgery	0.000	0.998	0.001
J95.2 Acute pulmonary insufficiency following nonthoracic surgery	0.000	0.998	0.001
J95.1 Acute pulmonary insufficiency following thoracic surgery	0.000	0.998	0.001
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.001	0.998	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.001	0.998	0.000
T83.2 Mechanical complication of graft of urinary organ	0.000	0.998	0.001
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.000	0.998	0.001
S92.30 Fracture of metatarsal bone (closed)	0.002	0.998	0.000
C16.3 Pyloric antrum	0.001	0.998	0.000
C16.2 Body of stomach	0.001	0.998	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.000	0.998	0.001
S22.20 Fracture of sternum (closed)	0.001	0.998	0.000
C15.8 Overlapping lesion of oesophagus	0.001	0.998	0.000
C15.3 Upper third of oesophagus	0.001	0.998	0.000
C15.2 Abdominal part of oesophagus	0.001	0.998	0.000
C15.1 Thoracic part of oesophagus	0.001	0.998	0.000
C15.0 Cervical part of oesophagus	0.001	0.998	0.000
I20.1 Angina pectoris with documented spasm	0.002	0.998	0.000
Q54.9 Hypospadias, unspecified	0.001	0.998	0.000
Q82.8 Other specified congenital malformations of skin	0.001	0.998	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.001	0.998	0.000
W25.09 Contact with sharp glass; Home; During unspecified activity	0.001	0.998	0.000
W25.03 Contact with sharp glass; Home; While engaged in other types of work	0.001	0.998	0.000
W25.18 Contact with sharp glass; Residential institution;While engaged in other specified activities	0.001	0.998	0.000
W25.52 Contact with sharp glass; Trade and service area;While working for income	0.001	0.998	0.000
W25.62 Contact with sharp glass; Industrial and construction area ;While working for income	0.001	0.998	0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.002	0.998	0.000
Q12.0 Congenital cataract	0.001	0.998	0.000
C22.7 Other specified carcinomas of liver	0.001	0.999	0.000
C22.4 Other sarcomas of liver	0.001	0.999	0.000
C22.3 Angiosarcoma of liver	0.001	0.999	0.000
C22.2 Hepatoblastoma	0.001	0.999	0.000
C44.6 Skin of upper limb, including shoulder	0.000	0.999	0.001
F30.8 Other manic episodes	0.001	0.999	0.000
F30.1 Mania without psychotic symptoms	0.001	0.999	0.000
Q83.9 Congenital malformation of breast, unspecified	0.001	0.999	0.000
Q83.3 Accessory nipple	0.001	0.999	0.000
Q83.2 Absent nipple	0.001	0.999	0.000
Q83.0 Congenital absence of breast with absent nipple	0.001	0.999	0.000
S22.4 Multiple fractures of ribs	0.001	0.999	0.000
I62 Other nontraumatic intracranial haemorrhage	0.000	0.999	0.001
C21.1 Anal canal	0.001	0.999	0.000
T78.8 Other adverse effects, not elsewhere classified	0.001	0.999	0.000
J00 Acute nasopharyngitis [common cold]	0.001	0.999	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.000	0.999	0.001
F30.2 Mania with psychotic symptoms	0.001	0.999	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.999	0.001
T40.2 Other opioids	0.001	0.999	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.001	0.999	0.000
C21.0 Anus, unspecified	0.001	0.999	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.001	0.999	0.000
F34.8 Other persistent mood [affective] disorders	0.001	0.999	0.000
F34.0 Cyclothymia	0.001	0.999	0.000
Q80.9 Congenital ichthyosis, unspecified	0.001	0.999	0.000
Q80.8 Other congenital ichthyosis	0.001	0.999	0.000
Q80.4 Harlequin foetus	0.001	0.999	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.001	0.999	0.000
Q80.2 Lamellar ichthyosis	0.001	0.999	0.000
Q80.1 X-linked ichthyosis	0.001	0.999	0.000
Q80.0 Ichthyosis vulgaris	0.001	0.999	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.001	0.999	0.000
Q81.8 Other epidermolysis bullosa	0.001	0.999	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.001	0.999	0.000
Q81.1 Epidermolysis bullosa letalis	0.001	0.999	0.000
Q81.0 Epidermolysis bullosa simplex	0.001	0.999	0.000
Q84.9 Congenital malformation of integument, unspecified	0.001	0.999	0.000
Q84.8 Other specified congenital malformations of integument	0.001	0.999	0.000
Q84.6 Other congenital malformations of nails	0.001	0.999	0.000
Q84.5 Enlarged and hypertrophic nails	0.001	0.999	0.000
Q84.4 Congenital leukonychia	0.001	0.999	0.000
Q84.3 Anonychia	0.001	0.999	0.000
Q84.2 Other congenital malformations of hair	0.001	0.999	0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.001	0.999	0.000
Q84.0 Congenital alopecia	0.001	0.999	0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.001	0.999	0.000
Q86.2 Dysmorphism due to warfarin	0.001	0.999	0.000
Q86.1 Foetal hydantoin syndrome	0.001	0.999	0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.001	0.999	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.001	0.999	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.001	0.999	0.000
T46.7 Peripheral vasodilators	0.001	0.999	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.001	0.999	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.001	0.999	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.999	0.000
C22.1 Intrahepatic bile duct carcinoma	0.001	0.999	0.000
F30.9 Manic episode, unspecified	0.001	0.999	0.000
G93.8 Other specified disorders of brain	0.001	0.999	0.001
J43.2 Centrilobular emphysema	0.001	0.999	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.001	0.999	0.000
S43.1 Dislocation of acromioclavicular joint	0.000	0.999	0.001
T36.3 Macrolides	0.001	0.999	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.001	0.999	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.001	0.999	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.001	0.999	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.001	0.999	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.001	0.999	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.001	0.999	0.000
T44.0 Anticholinesterase agents	0.001	0.999	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.001	0.999	0.000
J95.9 Postprocedural respiratory disorder, unspecified	0.000	0.999	0.001
O42.9 Premature rupture of membranes, unspecified	0.000	0.999	0.001
Q82.9 Congenital malformation of skin, unspecified	0.001	0.999	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.001	0.999	0.000
Q82.3 Incontinentia pigmenti	0.001	0.999	0.000
Q82.1 Xeroderma pigmentosum	0.001	0.999	0.000
Q82.0 Hereditary lymphoedema	0.001	0.999	0.000
S22.2 Fracture of sternum	0.001	0.999	0.000
T78.9 Adverse effect, unspecified	0.001	0.999	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.000	0.999	0.001
S22.51 Flail chest (open)	0.001	0.999	0.000
S42.20 Fracture of upper end of humerus (closed)	0.000	0.999	0.001
Q63.9 Congenital malformation of kidney, unspecified	0.000	0.999	0.001
Q63.8 Other specified congenital malformations of kidney	0.000	0.999	0.001
Q63.3 Hyperplastic and giant kidney	0.000	0.999	0.001
Q82.2 Mastocytosis	0.001	0.999	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.000	0.999	0.001
S43.6 Sprain and strain of sternoclavicular joint	0.000	0.999	0.001
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.000	0.999	0.001
S43.2 Dislocation of sternoclavicular joint	0.000	0.999	0.001
T78.1 Other adverse food reactions, not elsewhere classified	0.001	0.999	0.000
F69 Unspecified disorder of adult personality and behaviour	0.001	0.999	0.000
Q64 Other congenital malformations of urinary system	0.000	0.999	0.001
F60-F69 Disorders of adult personality and behaviour	0.001	0.999	0.000
C18.6 Descending colon	0.001	0.999	0.000
F30.0 Hypomania	0.001	0.999	0.000
J95.0 Tracheostomy malfunction	0.000	0.999	0.001
Q63.2 Ectopic kidney	0.000	0.999	0.001
Q54 Hypospadias	0.001	0.999	0.000
C18.5 Splenic flexure	0.001	0.999	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.001	0.999	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.001	0.999	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.001	0.999	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.001	0.999	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.001	0.999	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.001	0.999	0.000
S65.1 Injury of radial artery at wrist and hand level	0.001	0.999	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.001	0.999	0.000
T79.6 Traumatic ischaemia of muscle	0.001	0.999	0.000
Chapter V Mental and behavioural disorders	0.001	0.999	0.000
H02.3 Blepharochalasis	0.000	0.999	0.001
I62.1 Nontraumatic extradural haemorrhage	0.000	0.999	0.001
Q54.0 Hypospadias, balanic	0.001	0.999	0.000
S43.4 Sprain and strain of shoulder joint	0.000	0.999	0.001
Z29.2 Other prophylactic chemotherapy	0.001	0.999	0.000
T78 Adverse effects, not elsewhere classified	0.001	0.999	0.000
S22.41 Multiple fractures of ribs (open)	0.001	0.999	0.000
L90.5 Scar conditions and fibrosis of skin	0.000	0.999	0.001
Q62.8 Other congenital malformations of ureter	0.000	0.999	0.001
Q62.7 Congenital vesico-uretero-renal reflux	0.000	0.999	0.001
Q62.6 Malposition of ureter	0.000	0.999	0.001
Q62.5 Duplication of ureter	0.000	0.999	0.001
Q62.4 Agenesis of ureter	0.000	0.999	0.001
Q62.3 Other obstructive defects of renal pelvis and ureter	0.000	0.999	0.001
Q62.2 Congenital megaloureter	0.000	0.999	0.001
Q62.1 Atresia and stenosis of ureter	0.000	0.999	0.001
Q62.0 Congenital hydronephrosis	0.000	0.999	0.001
Q83.8 Other congenital malformations of breast	0.001	0.999	0.000
R73.0 Abnormal glucose tolerance test	0.000	0.999	0.001
I42 Cardiomyopathy	0.000	0.999	0.001
N88 Other noninflammatory disorders of cervix uteri	0.001	0.999	0.000
T36 Poisoning by systemic antibiotics	0.001	0.999	0.000
C16.0 Cardia	0.001	0.999	0.000
C18.3 Hepatic flexure	0.001	0.999	0.000
C22.0 Liver cell carcinoma	0.001	0.999	0.000
F32.0 Mild depressive episode	0.001	0.999	0.000
H33.3 Retinal breaks without detachment	0.001	0.999	0.000
H54.9 Unspecified visual impairment (binocular)	0.001	0.999	0.000
F64 Gender identity disorders	0.001	0.999	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.001	0.999	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.001	0.999	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.001	0.999	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations