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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1063478
log Bayes Factor = 17.154
Chromosome 6   position 32,917,544  (GRCh37) Explore rs1063478 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
E10.9 Without complications
0.000 0.015 0.985
E10 Insulin-dependent diabetes mellitus
0.000 0.015 0.985
E10.3 With ophthalmic complications
0.000 0.039 0.961
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.061 0.939
E05.9 Thyrotoxicosis, unspecified
0.000 0.062 0.938
E00-E07 Disorders of thyroid gland
0.000 0.065 0.935
E10-E14 Diabetes mellitus
0.000 0.071 0.929
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.075 0.925
E10.1 With ketoacidosis
0.000 0.080 0.920
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.090 0.910
E03 Other hypothyroidism
0.000 0.093 0.907
E03.9 Hypothyroidism, unspecified
0.000 0.107 0.893
L40.8 Other psoriasis
0.831 0.169 0.000
J47 Bronchiectasis
0.000 0.170 0.830
L40.0 Psoriasis vulgaris
0.818 0.181 0.000
E10.4 With neurological complications
0.000 0.185 0.815
J45.9 Asthma, unspecified
0.000 0.212 0.788
J45 Asthma
0.000 0.221 0.779
J40-J47 Chronic lower respiratory diseases
0.000 0.225 0.775
E10.0 With coma
0.000 0.234 0.766
E40-E46 Malnutrition
0.000 0.241 0.759
E10.5 With peripheral circulatory complications
0.000 0.244 0.756
E07 Other disorders of thyroid
0.000 0.248 0.752
K90 Intestinal malabsorption
0.000 0.263 0.737
E65-E68 Obesity and other hyperalimentation
0.000 0.272 0.728
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
L40.1 Generalised pustular psoriasis
0.717 0.283 0.000
E10.7 With multiple complications
0.000 0.294 0.706
E10.6 With other specified complications
0.000 0.294 0.706
K90.9 Intestinal malabsorption, unspecified
0.000 0.317 0.683
E03.8 Other specified hypothyroidism
0.000 0.317 0.683
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.326 0.674
E05.8 Other thyrotoxicosis
0.000 0.327 0.673
E05.5 Thyroid crisis or storm
0.000 0.327 0.673
E05.4 Thyrotoxicosis factitia
0.000 0.327 0.673
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.327 0.673
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.327 0.673
M06.9 Rheumatoid arthritis, unspecified
0.000 0.328 0.672
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.329 0.670
E00 Congenital iodine-deficiency syndrome
0.000 0.329 0.670
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.329 0.670
E10.8 With unspecified complications
0.000 0.333 0.667
E12 Malnutrition-related diabetes mellitus
0.000 0.334 0.666
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.344 0.656
E03.5 Myxoedema coma
0.000 0.350 0.650
E03.4 Atrophy of thyroid (acquired)
0.000 0.350 0.650
E03.3 Postinfectious hypothyroidism
0.000 0.350 0.650
E03.1 Congenital hypothyroidism without goitre
0.000 0.350 0.650
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.350 0.650
E07.9 Disorder of thyroid, unspecified
0.000 0.356 0.644
E46 Unspecified protein-energy malnutrition
0.000 0.360 0.640
M06 Other rheumatoid arthritis
0.000 0.364 0.635
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.364 0.636
E65 Localised adiposity
0.000 0.371 0.629
M06.0 Seronegative rheumatoid arthritis
0.000 0.381 0.618
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.388 0.612
E20-E35 Disorders of other endocrine glands
0.000 0.396 0.604
E50-E64 Other nutritional deficiencies
0.000 0.396 0.604
J42 Unspecified chronic bronchitis
0.000 0.396 0.604
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.407 0.593
E10.2 With renal complications
0.000 0.416 0.583
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.429 0.571
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.441 0.559
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.441 0.559
J45.8 Mixed asthma
0.000 0.442 0.558
J45.1 Nonallergic asthma
0.000 0.442 0.558
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.443 0.557
J41 Simple and mucopurulent chronic bronchitis
0.000 0.444 0.556
E13 Other specified diabetes mellitus
0.000 0.445 0.555
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.456 0.544
E45 Retarded development following protein-energy malnutrition
0.000 0.456 0.544
E43 Unspecified severe protein-energy malnutrition
0.000 0.456 0.544
E42 Marasmic kwashiorkor
0.000 0.456 0.544
E41 Nutritional marasmus
0.000 0.456 0.544
E40 Kwashiorkor
0.000 0.456 0.544
L40-L45 Papulosquamous disorders
0.541 0.459 0.000
E07.1 Dyshormogenetic goitre
0.000 0.461 0.539
E07.0 Hypersecretion of calcitonin
0.000 0.461 0.539
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.466 0.534
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.469 0.531
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.469 0.531
M06.4 Inflammatory polyarthropathy
0.000 0.471 0.529
K90.8 Other intestinal malabsorption
0.000 0.472 0.528
K90.3 Pancreatic steatorrhoea
0.000 0.472 0.528
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.472 0.528
K90.1 Tropical sprue
0.000 0.472 0.528
E67 Other hyperalimentation
0.000 0.478 0.522
E68 Sequelae of hyperalimentation
0.000 0.478 0.522
E21.3 Hyperparathyroidism, unspecified
0.000 0.480 0.520
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.486 0.514
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.505 0.495
M06.3 Rheumatoid nodule
0.000 0.505 0.495
E16 Other disorders of pancreatic internal secretion
0.000 0.506 0.494
E07.8 Other specified disorders of thyroid
0.000 0.506 0.493
J43 Emphysema
0.000 0.507 0.493
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.510 0.490
E15 Nondiabetic hypoglycaemic coma
0.000 0.516 0.483
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.518 0.482
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.519 0.481
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.519 0.481
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.519 0.481
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.519 0.481
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.519 0.481
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.519 0.481
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.519 0.481
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.519 0.481
E12.9 Without complications
0.000 0.522 0.477
E12.8 With unspecified complications
0.000 0.522 0.477
E12.7 With multiple complications
0.000 0.522 0.477
E12.6 With other specified complications
0.000 0.522 0.477
E12.5 With peripheral circulatory complications
0.000 0.522 0.477
E12.4 With neurological complications
0.000 0.522 0.477
E12.3 With ophthalmic complications
0.000 0.522 0.477
E12.2 With renal complications
0.000 0.522 0.477
E12.1 With ketoacidosis
0.000 0.522 0.477
E12.0 With coma
0.000 0.522 0.477
J45.0 Predominantly allergic asthma
0.000 0.523 0.477
E55 Vitamin D deficiency
0.000 0.526 0.474
E06 Thyroiditis
0.000 0.537 0.462
E28 Ovarian dysfunction
0.000 0.539 0.461
M06.8 Other specified rheumatoid arthritis
0.000 0.544 0.456
M06.2 Rheumatoid bursitis
0.000 0.544 0.456
M06.1 Adult-onset Still's disease
0.000 0.544 0.456
E27 Other disorders of adrenal gland
0.000 0.545 0.455
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.549 0.451
L43 Lichen planus
0.446 0.554 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.556 0.443
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.556 0.443
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.556 0.443
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.556 0.443
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.556 0.443
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.556 0.443
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.556 0.443
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.556 0.443
E14 Unspecified diabetes mellitus
0.000 0.559 0.441
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.564 0.436
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.567 0.433
E32 Diseases of thymus
0.000 0.567 0.433
E31 Polyglandular dysfunction
0.000 0.567 0.433
E30 Disorders of puberty, not elsewhere classified
0.000 0.567 0.433
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.567 0.433
E63 Other nutritional deficiencies
0.000 0.567 0.433
E56 Other vitamin deficiencies
0.000 0.567 0.433
E51 Thiamine deficiency
0.000 0.567 0.433
E50 Vitamin A deficiency
0.000 0.567 0.433
E60 Dietary zinc deficiency
0.000 0.567 0.433
E59 Dietary selenium deficiency
0.000 0.567 0.433
E58 Dietary calcium deficiency
0.000 0.567 0.433
E54 Ascorbic acid deficiency
0.000 0.567 0.433
E52 Niacin deficiency [pellagra]
0.000 0.567 0.433
E66 Obesity
0.000 0.568 0.432
E26 Hyperaldosteronism
0.000 0.574 0.426
E22 Hyperfunction of pituitary gland
0.000 0.577 0.423
M06.34 Rheumatoid nodule (Hand)
0.000 0.583 0.416
E27.1 Primary adrenocortical insufficiency
0.000 0.585 0.414
E29 Testicular dysfunction
0.000 0.587 0.412
E34 Other endocrine disorders
0.000 0.588 0.412
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.594 0.406
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.599 0.400
E21.4 Other specified disorders of parathyroid gland
0.000 0.599 0.400
E21.2 Other hyperparathyroidism
0.000 0.599 0.400
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.601 0.399
J41.1 Mucopurulent chronic bronchitis
0.000 0.601 0.399
J41.0 Simple chronic bronchitis
0.000 0.601 0.399
E13.8 With unspecified complications
0.000 0.602 0.398
E13.7 With multiple complications
0.000 0.602 0.398
E13.6 With other specified complications
0.000 0.602 0.398
E13.5 With peripheral circulatory complications
0.000 0.602 0.398
E13.4 With neurological complications
0.000 0.602 0.398
E13.3 With ophthalmic complications
0.000 0.602 0.398
E13.2 With renal complications
0.000 0.602 0.398
E13.1 With ketoacidosis
0.000 0.602 0.398
E13.0 With coma
0.000 0.602 0.398
L43.9 Lichen planus, unspecified
0.396 0.604 0.000
J46 Status asthmaticus
0.000 0.605 0.395
E44.1 Mild protein-energy malnutrition
0.000 0.610 0.390
E44.0 Moderate protein-energy malnutrition
0.000 0.610 0.390
E66.8 Other obesity
0.000 0.610 0.390
E20 Hypoparathyroidism
0.000 0.611 0.389
E53 Deficiency of other B group vitamins
0.000 0.611 0.389
L44 Other papulosquamous disorders
0.388 0.612 0.000
L41 Parapsoriasis
0.388 0.612 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.388 0.612 0.000
L42 Pityriasis rosea
0.388 0.612 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.617 0.383
E24 Cushing's syndrome
0.000 0.619 0.380
E27.9 Disorder of adrenal gland, unspecified
0.000 0.620 0.380
E55.9 Vitamin D deficiency, unspecified
0.000 0.620 0.380
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.620 0.379
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.620 0.379
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.620 0.379
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.620 0.379
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.620 0.379
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.620 0.379
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.620 0.379
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.620 0.379
E25 Adrenogenital disorders
0.000 0.621 0.379
E67.8 Other specified hyperalimentation
0.000 0.626 0.374
E67.3 Hypervitaminosis D
0.000 0.626 0.374
E67.2 Megavitamin-B6 syndrome
0.000 0.626 0.374
E67.1 Hypercarotenaemia
0.000 0.626 0.374
E67.0 Hypervitaminosis A
0.000 0.626 0.374
E61 Deficiency of other nutrient elements
0.000 0.636 0.364
E21.0 Primary hyperparathyroidism
0.000 0.639 0.361
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.645 0.355
M06.38 Rheumatoid nodule (Other)
0.000 0.645 0.355
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.645 0.355
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.645 0.355
M06.33 Rheumatoid nodule (Forearm)
0.000 0.645 0.355
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.645 0.355
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.645 0.355
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.645 0.355
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.645 0.355
E16.4 Abnormal secretion of gastrin
0.000 0.645 0.355
E16.3 Increased secretion of glucagon
0.000 0.645 0.355
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.645 0.355
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.646 0.354
J43.8 Other emphysema
0.000 0.646 0.353
J43.1 Panlobular emphysema
0.000 0.646 0.353
J43.0 MacLeod's syndrome
0.000 0.646 0.353
E14.3 With ophthalmic complications
0.000 0.648 0.352
E28.2 Polycystic ovarian syndrome
0.000 0.653 0.347
E28.3 Primary ovarian failure
0.000 0.656 0.343
E55.0 Rickets, active
0.000 0.660 0.340
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.664 0.336
E16.1 Other hypoglycaemia
0.000 0.667 0.333
J40 Bronchitis, not specified as acute or chronic
0.000 0.667 0.333
E06.5 Other chronic thyroiditis
0.000 0.668 0.332
E06.4 Drug-induced thyroiditis
0.000 0.668 0.332
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.668 0.332
E06.1 Subacute thyroiditis
0.000 0.668 0.332
E06.0 Acute thyroiditis
0.000 0.668 0.332
E28.9 Ovarian dysfunction, unspecified
0.000 0.669 0.331
E28.8 Other ovarian dysfunction
0.000 0.669 0.331
E28.1 Androgen excess
0.000 0.669 0.331
E28.0 Oestrogen excess
0.000 0.669 0.331
J43.2 Centrilobular emphysema
0.000 0.671 0.329
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.673 0.327
M06.18 Adult-onset Still's disease (Other)
0.000 0.673 0.327
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.673 0.327
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.673 0.327
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.673 0.327
M06.14 Adult-onset Still's disease (Hand)
0.000 0.673 0.327
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.673 0.327
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.673 0.327
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.673 0.327
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.673 0.327
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.673 0.327
M06.28 Rheumatoid bursitis (Other)
0.000 0.673 0.327
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.673 0.327
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.673 0.327
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.673 0.327
M06.24 Rheumatoid bursitis (Hand)
0.000 0.673 0.327
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.673 0.327
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.673 0.327
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.673 0.327
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.673 0.327
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.673 0.327
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.673 0.327
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.673 0.327
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.673 0.327
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.673 0.327
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.673 0.327
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.673 0.327
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.673 0.327
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.673 0.327
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.673 0.327
E27.5 Adrenomedullary hyperfunction
0.000 0.674 0.326
E27.0 Other adrenocortical overactivity
0.000 0.674 0.326
J43.9 Emphysema, unspecified
0.000 0.679 0.321
L43.3 Subacute (active) lichen planus
0.320 0.680 0.000
L43.2 Lichenoid drug reaction
0.320 0.680 0.000
L43.1 Bullous lichen planus
0.320 0.680 0.000
L43.0 Hypertrophic lichen planus
0.320 0.680 0.000
E14.7 With multiple complications
0.000 0.684 0.316
E14.6 With other specified complications
0.000 0.684 0.316
E14.5 With peripheral circulatory complications
0.000 0.684 0.316
E14.4 With neurological complications
0.000 0.684 0.316
E14.2 Withrenal complications
0.000 0.684 0.316
E14.1 With ketoacidosis
0.000 0.684 0.316
E14.0 With coma
0.000 0.684 0.316
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.685 0.315
E34.8 Other specified endocrine disorders
0.000 0.687 0.313
E30.9 Disorder of puberty, unspecified
0.000 0.689 0.311
E30.8 Other disorders of puberty
0.000 0.689 0.311
E30.1 Precocious puberty
0.000 0.689 0.311
E30.0 Delayed puberty
0.000 0.689 0.311
E31.9 Polyglandular dysfunction, unspecified
0.000 0.689 0.311
E31.8 Other polyglandular dysfunction
0.000 0.689 0.311
E31.1 Polyglandular hyperfunction
0.000 0.689 0.311
E31.0 Autoimmune polyglandular failure
0.000 0.689 0.311
E32.9 Disease of thymus, unspecified
0.000 0.689 0.311
E32.8 Other diseases of thymus
0.000 0.689 0.311
E32.1 Abscess of thymus
0.000 0.689 0.311
E32.0 Persistent hyperplasia of thymus
0.000 0.689 0.311
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.689 0.311
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.689 0.311
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.689 0.311
E50.9 Vitamin A deficiency, unspecified
0.000 0.689 0.311
E50.8 Other manifestations of vitamin A deficiency
0.000 0.689 0.311
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.689 0.311
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.689 0.311
E50.5 Vitamin A deficiency with night blindness
0.000 0.689 0.311
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.689 0.311
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.689 0.311
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.689 0.311
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.689 0.311
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.689 0.311
E51.9 Thiamine deficiency, unspecified
0.000 0.689 0.311
E51.8 Other manifestations of thiamine deficiency
0.000 0.689 0.311
E51.2 Wernicke's encephalopathy
0.000 0.689 0.311
E51.1 Beriberi
0.000 0.689 0.311
E56.9 Vitamin deficiency, unspecified
0.000 0.689 0.311
E56.8 Deficiency of other vitamins
0.000 0.689 0.311
E56.1 Deficiency of vitamin K
0.000 0.689 0.311
E56.0 Deficiency of vitamin E
0.000 0.689 0.311
E63.9 Nutritional deficiency, unspecified
0.000 0.689 0.311
E63.8 Other specified nutritional deficiencies
0.000 0.689 0.311
E63.1 Imbalance of constituents of food intake
0.000 0.689 0.311
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.689 0.311
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.689 0.311
E64.8 Sequelae of other nutritional deficiencies
0.000 0.689 0.311
E64.3 Sequelae of rickets
0.000 0.689 0.311
E64.2 Sequelae of vitamin C deficiency
0.000 0.689 0.311
E64.1 Sequelae of vitamin A deficiency
0.000 0.689 0.311
E64.0 Sequelae of protein-energy malnutrition
0.000 0.689 0.311
E66.1 Drug-induced obesity
0.000 0.690 0.310
E22.1 Hyperprolactinaemia
0.000 0.690 0.310
E26.9 Hyperaldosteronism, unspecified
0.000 0.694 0.305
E26.8 Other hyperaldosteronism
0.000 0.694 0.305
E26.1 Secondary hyperaldosteronism
0.000 0.694 0.305
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.697 0.303
E22.8 Other hyperfunction of pituitary gland
0.000 0.697 0.303
E27.8 Other specified disorders of adrenal gland
0.000 0.700 0.300
E22.0 Acromegaly and pituitary gigantism
0.000 0.700 0.299
E26.0 Primary hyperaldosteronism
0.000 0.702 0.298
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.703 0.297
E29.9 Testicular dysfunction, unspecified
0.000 0.704 0.296
E29.8 Other testicular dysfunction
0.000 0.704 0.296
E29.0 Testicular hyperfunction
0.000 0.704 0.296
E34.5 Androgen resistance syndrome
0.000 0.705 0.295
E34.4 Constitutional tall stature
0.000 0.705 0.295
E34.3 Short stature, not elsewhere classified
0.000 0.705 0.295
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.705 0.295
E34.1 Other hypersecretion of intestinal hormones
0.000 0.705 0.295
E34.0 Carcinoid syndrome
0.000 0.705 0.295
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.706 0.294
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.711 0.289
E14.8 With unspecified complications
0.000 0.711 0.288
E13.9 Without complications
0.000 0.713 0.287
E04 Other non-toxic goitre
0.000 0.720 0.280
E20.8 Other hypoparathyroidism
0.000 0.721 0.279
E20.1 Pseudohypoparathyroidism
0.000 0.721 0.279
E20.0 Idiopathic hypoparathyroidism
0.000 0.721 0.279
E53.9 Vitamin B deficiency, unspecified
0.000 0.721 0.279
E53.1 Pyridoxine deficiency
0.000 0.721 0.279
E53.0 Riboflavin deficiency
0.000 0.721 0.279
L41.9 Parapsoriasis, unspecified
0.278 0.722 0.000
L41.8 Other parapsoriasis
0.278 0.722 0.000
L41.5 Retiform parapsoriasis
0.278 0.722 0.000
L41.4 Large plaque parapsoriasis
0.278 0.722 0.000
L41.3 Small plaque parapsoriasis
0.278 0.722 0.000
L41.2 Lymphomatoid papulosis
0.278 0.722 0.000
L41.1 Pityriasis lichenoides chronica
0.278 0.722 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.278 0.722 0.000
L44.9 Papulosquamous disorder, unspecified
0.278 0.722 0.000
L44.8 Other specified papulosquamous disorders
0.278 0.722 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.278 0.722 0.000
L44.3 Lichen ruber moniliformis
0.278 0.722 0.000
L44.2 Lichen striatus
0.278 0.722 0.000
L44.1 Lichen nitidus
0.278 0.722 0.000
L44.0 Pityriasis rubra pilaris
0.278 0.722 0.000
E66.0 Obesity due to excess calories
0.000 0.723 0.277
L43.8 Other lichen planus
0.276 0.723 0.000
E29.1 Testicular hypofunction
0.000 0.725 0.275
E06.9 Thyroiditis, unspecified
0.001 0.726 0.274
E24.8 Other Cushing's syndrome
0.000 0.727 0.273
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.727 0.273
E24.3 Ectopic ACTH syndrome
0.000 0.727 0.273
E24.1 Nelson's syndrome
0.000 0.727 0.273
E24.0 Pituitary-dependent Cushing's disease
0.000 0.727 0.273
E25.9 Adrenogenital disorder, unspecified
0.000 0.728 0.272
E25.8 Other adrenogenital disorders
0.000 0.728 0.272
E61.9 Deficiency of nutrient element, unspecified
0.000 0.739 0.261
E61.8 Deficiency of other specified nutrient elements
0.000 0.739 0.261
E61.7 Deficiency of multiple nutrient elements
0.000 0.739 0.261
E61.6 Vanadium deficiency
0.000 0.739 0.261
E61.5 Molybdenum deficiency
0.000 0.739 0.261
E61.4 Chromium deficiency
0.000 0.739 0.261
E61.3 Manganese deficiency
0.000 0.739 0.261
E61.2 Magnesium deficiency
0.000 0.739 0.261
E61.0 Copper deficiency
0.000 0.739 0.261
E24.9 Cushing's syndrome, unspecified
0.000 0.742 0.258
E34.9 Endocrine disorder, unspecified
0.000 0.751 0.249
Chapter X Diseases of the respiratory system
0.000 0.753 0.247
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.758 0.241
E24.2 Drug-induced Cushing's syndrome
0.000 0.760 0.240
J20-J22 Other acute lower respiratory infections
0.000 0.761 0.239
E20.9 Hypoparathyroidism, unspecified
0.000 0.765 0.235
E53.8 Deficiency of other specified B group vitamins
0.000 0.765 0.235
J22 Unspecified acute lower respiratory infection
0.000 0.767 0.233
J44 Other chronic obstructive pulmonary disease
0.000 0.767 0.233
E06.3 Autoimmune thyroiditis
0.000 0.772 0.227
E23 Hypofunction and other disorders of pituitary gland
0.000 0.781 0.219
E27.2 Addisonian crisis
0.001 0.781 0.219
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.001 0.782 0.217
E04.2 Non-toxic multinodular goitre
0.000 0.782 0.218
E04.8 Other specified non-toxic goitre
0.000 0.799 0.201
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.806 0.194
E61.1 Iron deficiency
0.000 0.807 0.192
J09-J18 Influenza and pneumonia
0.000 0.810 0.190
J21 Acute bronchiolitis
0.000 0.814 0.186
J60-J70 Lung diseases due to external agents
0.000 0.819 0.181
J15 Bacterial pneumonia, not elsewhere classified
0.000 0.828 0.172
J00-J06 Acute upper respiratory infections
0.000 0.828 0.172
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.830 0.170
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.843 0.157
E23.1 Drug-induced hypopituitarism
0.000 0.843 0.157
J20 Acute bronchitis
0.000 0.844 0.156
E23.7 Disorder of pituitary gland, unspecified
0.000 0.845 0.155
J04 Acute laryngitis and tracheitis
0.000 0.851 0.149
J69 Pneumonitis due to solids and liquids
0.000 0.851 0.149
J21.9 Acute bronchiolitis, unspecified
0.000 0.852 0.147
J17 Pneumonia in diseases classified elsewhere
0.000 0.857 0.142
J15.1 Pneumonia due to Pseudomonas
0.000 0.858 0.142
J00 Acute nasopharyngitis [common cold]
0.000 0.859 0.141
J15.0 Pneumonia due to Klebsiella pneumoniae
0.000 0.862 0.138
J13 Pneumonia due to Streptococcus pneumoniae
0.000 0.862 0.138
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.000 0.862 0.138
J15.2 Pneumonia due to staphylococcus
0.000 0.862 0.138
J14 Pneumonia due to Haemophilus influenzae
0.000 0.864 0.136
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.000 0.864 0.136
J12 Viral pneumonia, not elsewhere classified
0.000 0.864 0.136
J09 Influenza due to certain identified influenza virus
0.000 0.864 0.136
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.866 0.134
E04.0 Non-toxic diffuse goitre
0.001 0.866 0.133
J21.8 Acute bronchiolitis due to other specified organisms
0.000 0.867 0.133
J21.1 Acute bronchiolitis due to human metapneumovirus
0.000 0.867 0.133
J21.0 Acute bronchiolitis due to respiratory syncytial virus
0.000 0.867 0.133
J10 Influenza due to identified influenza virus
0.000 0.868 0.132
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.869 0.131
J04.0 Acute laryngitis
0.000 0.869 0.131
J70 Respiratory conditions due to other external agents
0.000 0.870 0.130
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.000 0.870 0.130
J66 Airway disease due to specific organic dust
0.000 0.870 0.130
J63 Pneumoconiosis due to other inorganic dusts
0.000 0.870 0.130
J62 Pneumoconiosis due to dust containing silica
0.000 0.870 0.130
J65 Pneumoconiosis associated with tuberculosis
0.000 0.870 0.130
J64 Unspecified pneumoconiosis
0.000 0.870 0.130
J60 Coalworker's pneumoconiosis
0.000 0.870 0.130
E04.1 Non-toxic single thyroid nodule
0.000 0.871 0.129
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.872 0.128
J11 Influenza, virus not identified
0.000 0.873 0.127
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.000 0.874 0.126
J69.0 Pneumonitis due to food and vomit
0.000 0.875 0.125
J15.9 Bacterial pneumonia, unspecified
0.000 0.876 0.124
J15.8 Other bacterial pneumonia
0.000 0.876 0.124
J15.6 Pneumonia due to other aerobic Gram-negative bacteria
0.000 0.876 0.124
J15.5 Pneumonia due to Escherichia coli
0.000 0.876 0.124
J15.3 Pneumonia due to streptococcus, group B
0.000 0.876 0.124
E23.2 Diabetes insipidus
0.001 0.878 0.122
J85 Abscess of lung and mediastinum
0.000 0.880 0.120
E23.0 Hypopituitarism
0.000 0.883 0.117
J86 Pyothorax
0.000 0.883 0.117
E23.6 Other disorders of pituitary gland
0.001 0.883 0.116
J15.4 Pneumonia due to other streptococci
0.000 0.884 0.116
J90-J94 Other diseases of pleura
0.000 0.886 0.114
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.887 0.113
J95-J99 Other diseases of the respiratory system
0.000 0.887 0.113
J04.1 Acute tracheitis
0.000 0.888 0.112
J20.8 Acute bronchitis due to other specified organisms
0.000 0.888 0.112
J20.7 Acute bronchitis due to echovirus
0.000 0.888 0.112
J20.6 Acute bronchitis due to rhinovirus
0.000 0.888 0.112
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.888 0.112
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.888 0.112
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.888 0.112
J20.2 Acute bronchitis due to streptococcus
0.000 0.888 0.112
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.888 0.112
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.888 0.112
E04.9 Non-toxic goitre, unspecified
0.000 0.889 0.111
J17.3 Pneumonia in parasitic diseases
0.000 0.889 0.111
J30-J39 Other diseases of upper respiratory tract
0.000 0.892 0.108
J04.2 Acute laryngotracheitis
0.000 0.893 0.107
J69.1 Pneumonitis due to oils and essences
0.000 0.893 0.107
J69.8 Pneumonitis due to other solids and liquids
0.000 0.893 0.106
J06.9 Acute upper respiratory infection, unspecified
0.000 0.894 0.106
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.000 0.895 0.105
J03 Acute tonsillitis
0.000 0.895 0.104
J33 Nasal polyp
0.000 0.896 0.104
J17.2 Pneumonia in mycoses
0.000 0.896 0.104
J17.8 Pneumonia in other diseases classified elsewhere
0.000 0.898 0.102
J17.1 Pneumonia in viral diseases classified elsewhere
0.000 0.898 0.102
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.898 0.102
J84 Other interstitial pulmonary diseases
0.000 0.898 0.102

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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