TreeWAS – Variant ID: rs10744782

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E03 Other hypothyroidism	0.819	0.181	0.000
E03.8 Other specified hypothyroidism	0.741	0.259	0.000
E03.1 Congenital hypothyroidism without goitre	0.605	0.395	0.000
E03.5 Myxoedema coma	0.587	0.413	0.000
E03.4 Atrophy of thyroid (acquired)	0.587	0.413	0.000
E03.3 Postinfectious hypothyroidism	0.587	0.413	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.587	0.413	0.000
E00-E07 Disorders of thyroid gland	0.560	0.440	0.000
E06 Thyroiditis	0.539	0.461	0.000
E06.3 Autoimmune thyroiditis	0.519	0.481	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.442	0.557	0.000
E06.9 Thyroiditis, unspecified	0.420	0.580	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.412	0.588	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.402	0.598	0.000
E00 Congenital iodine-deficiency syndrome	0.402	0.598	0.000
E06.1 Subacute thyroiditis	0.396	0.604	0.000
E06.4 Drug-induced thyroiditis	0.387	0.613	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.387	0.613	0.000
E06.0 Acute thyroiditis	0.387	0.613	0.000
E06.5 Other chronic thyroiditis	0.383	0.616	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.375	0.625	0.000
E07 Other disorders of thyroid	0.350	0.650	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.340	0.660	0.000
Z95.4 Presence of other heart-valve replacement	0.321	0.679	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.288	0.712	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.288	0.712	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.288	0.712	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.288	0.712	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.288	0.712	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.288	0.712	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.288	0.712	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.288	0.712	0.000
E05.5 Thyroid crisis or storm	0.269	0.731	0.000
E05.4 Thyrotoxicosis factitia	0.269	0.731	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.269	0.731	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.269	0.731	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.267	0.733	0.000
E07.1 Dyshormogenetic goitre	0.251	0.749	0.000
E07.0 Hypersecretion of calcitonin	0.251	0.749	0.000
E05.9 Thyrotoxicosis, unspecified	0.246	0.754	0.000
E20-E35 Disorders of other endocrine glands	0.246	0.754	0.000
E27 Other disorders of adrenal gland	0.244	0.756	0.000
E50-E64 Other nutritional deficiencies	0.240	0.760	0.000
E07.9 Disorder of thyroid, unspecified	0.236	0.764	0.000
E61 Deficiency of other nutrient elements	0.234	0.766	0.000
E61.1 Iron deficiency	0.231	0.769	0.000
E05.8 Other thyrotoxicosis	0.231	0.769	0.000
E27.8 Other specified disorders of adrenal gland	0.231	0.769	0.000
E27.1 Primary adrenocortical insufficiency	0.219	0.781	0.000
E07.8 Other specified disorders of thyroid	0.218	0.781	0.000
E10-E14 Diabetes mellitus	0.218	0.782	0.000
E10 Insulin-dependent diabetes mellitus	0.217	0.783	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.206	0.794	0.000
Z95.2 Presence of prosthetic heart valve	0.204	0.796	0.000
E27.2 Addisonian crisis	0.203	0.797	0.000
E10.3 With ophthalmic complications	0.203	0.797	0.000
E24 Cushing's syndrome	0.198	0.802	0.000
E10.5 With peripheral circulatory complications	0.197	0.803	0.000
E40-E46 Malnutrition	0.196	0.804	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.195	0.805	0.000
E25 Adrenogenital disorders	0.195	0.805	0.000
E10.1 With ketoacidosis	0.194	0.806	0.000
E10.0 With coma	0.185	0.815	0.000
E20 Hypoparathyroidism	0.184	0.816	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.176	0.823	0.000
E32 Diseases of thymus	0.176	0.823	0.000
E31 Polyglandular dysfunction	0.176	0.823	0.000
E30 Disorders of puberty, not elsewhere classified	0.176	0.823	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.176	0.824	0.000
E58 Dietary calcium deficiency	0.175	0.825	0.000
E27.5 Adrenomedullary hyperfunction	0.175	0.825	0.000
E27.0 Other adrenocortical overactivity	0.175	0.825	0.000
C67 Malignant neoplasm of bladder	0.173	0.827	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.172	0.828	0.000
E63 Other nutritional deficiencies	0.172	0.828	0.000
E56 Other vitamin deficiencies	0.172	0.828	0.000
E50 Vitamin A deficiency	0.172	0.828	0.000
E60 Dietary zinc deficiency	0.172	0.828	0.000
E59 Dietary selenium deficiency	0.172	0.828	0.000
E54 Ascorbic acid deficiency	0.172	0.828	0.000
E52 Niacin deficiency [pellagra]	0.172	0.828	0.000
E26 Hyperaldosteronism	0.172	0.828	0.000
E10.4 With neurological complications	0.172	0.828	0.000
C67.2 Lateral wall of bladder	0.170	0.830	0.000
E61.2 Magnesium deficiency	0.169	0.831	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.169	0.831	0.000
E61.9 Deficiency of nutrient element, unspecified	0.168	0.832	0.000
E61.8 Deficiency of other specified nutrient elements	0.168	0.832	0.000
E61.7 Deficiency of multiple nutrient elements	0.168	0.832	0.000
E61.6 Vanadium deficiency	0.168	0.832	0.000
E61.5 Molybdenum deficiency	0.168	0.832	0.000
E61.4 Chromium deficiency	0.168	0.832	0.000
E61.3 Manganese deficiency	0.168	0.832	0.000
E61.0 Copper deficiency	0.168	0.832	0.000
E28 Ovarian dysfunction	0.168	0.832	0.000
C67.4 Posterior wall of bladder	0.167	0.833	0.000
C67.5 Bladder neck	0.164	0.836	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.158	0.842	0.000
E34 Other endocrine disorders	0.158	0.842	0.000
E27.9 Disorder of adrenal gland, unspecified	0.157	0.843	0.000
E51 Thiamine deficiency	0.157	0.843	0.000
E10.8 With unspecified complications	0.157	0.843	0.000
E24.0 Pituitary-dependent Cushing's disease	0.157	0.843	0.000
E12 Malnutrition-related diabetes mellitus	0.156	0.843	0.000
E10.7 With multiple complications	0.155	0.844	0.000
E23 Hypofunction and other disorders of pituitary gland	0.153	0.847	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.153	0.847	0.000
C67.1 Dome of bladder	0.153	0.847	0.000
E55 Vitamin D deficiency	0.150	0.850	0.000
E24.2 Drug-induced Cushing's syndrome	0.150	0.850	0.000
C67.6 Ureteric orifice	0.149	0.851	0.000
E29 Testicular dysfunction	0.148	0.852	0.000
E46 Unspecified protein-energy malnutrition	0.145	0.855	0.000
E24.9 Cushing's syndrome, unspecified	0.144	0.856	0.000
E28.3 Primary ovarian failure	0.143	0.857	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.143	0.857	0.000
E24.8 Other Cushing's syndrome	0.142	0.858	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.142	0.858	0.000
E24.3 Ectopic ACTH syndrome	0.142	0.858	0.000
E24.1 Nelson's syndrome	0.142	0.858	0.000
Z95.3 Presence of xenogenic heart valve	0.141	0.859	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.141	0.859	0.000
E45 Retarded development following protein-energy malnutrition	0.141	0.859	0.000
E43 Unspecified severe protein-energy malnutrition	0.141	0.859	0.000
E42 Marasmic kwashiorkor	0.141	0.859	0.000
E41 Nutritional marasmus	0.141	0.859	0.000
E40 Kwashiorkor	0.141	0.859	0.000
E25.9 Adrenogenital disorder, unspecified	0.140	0.860	0.000
E25.8 Other adrenogenital disorders	0.140	0.860	0.000
C67.8 Overlapping lesion of bladder	0.140	0.860	0.000
E10.6 With other specified complications	0.139	0.860	0.000
E20.9 Hypoparathyroidism, unspecified	0.139	0.861	0.000
E10.2 With renal complications	0.136	0.864	0.000
C67.3 Anterior wall of bladder	0.134	0.866	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.133	0.867	0.000
E20.8 Other hypoparathyroidism	0.132	0.868	0.000
E20.1 Pseudohypoparathyroidism	0.132	0.868	0.000
E20.0 Idiopathic hypoparathyroidism	0.132	0.868	0.000
E23.6 Other disorders of pituitary gland	0.132	0.868	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.131	0.869	0.001
E22 Hyperfunction of pituitary gland	0.128	0.872	0.000
E30.9 Disorder of puberty, unspecified	0.127	0.873	0.000
E30.8 Other disorders of puberty	0.127	0.873	0.000
E30.1 Precocious puberty	0.127	0.873	0.000
E30.0 Delayed puberty	0.127	0.873	0.000
E31.9 Polyglandular dysfunction, unspecified	0.127	0.873	0.000
E31.8 Other polyglandular dysfunction	0.127	0.873	0.000
E31.1 Polyglandular hyperfunction	0.127	0.873	0.000
E31.0 Autoimmune polyglandular failure	0.127	0.873	0.000
E32.9 Disease of thymus, unspecified	0.127	0.873	0.000
E32.8 Other diseases of thymus	0.127	0.873	0.000
E32.1 Abscess of thymus	0.127	0.873	0.000
E32.0 Persistent hyperplasia of thymus	0.127	0.873	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.127	0.873	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.127	0.873	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.127	0.873	0.000
C67.7 Urachus	0.124	0.876	0.000
E50.9 Vitamin A deficiency, unspecified	0.123	0.876	0.000
E50.8 Other manifestations of vitamin A deficiency	0.123	0.876	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.123	0.876	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.123	0.876	0.000
E50.5 Vitamin A deficiency with night blindness	0.123	0.876	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.123	0.876	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.123	0.876	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.123	0.876	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.123	0.876	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.123	0.876	0.000
E56.9 Vitamin deficiency, unspecified	0.123	0.876	0.000
E56.8 Deficiency of other vitamins	0.123	0.876	0.000
E56.1 Deficiency of vitamin K	0.123	0.876	0.000
E56.0 Deficiency of vitamin E	0.123	0.876	0.000
E63.9 Nutritional deficiency, unspecified	0.123	0.876	0.000
E63.8 Other specified nutritional deficiencies	0.123	0.876	0.000
E63.1 Imbalance of constituents of food intake	0.123	0.876	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.123	0.876	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.123	0.876	0.000
E64.8 Sequelae of other nutritional deficiencies	0.123	0.876	0.000
E64.3 Sequelae of rickets	0.123	0.876	0.000
E64.2 Sequelae of vitamin C deficiency	0.123	0.876	0.000
E64.1 Sequelae of vitamin A deficiency	0.123	0.876	0.000
E64.0 Sequelae of protein-energy malnutrition	0.123	0.876	0.000
E26.8 Other hyperaldosteronism	0.123	0.876	0.000
E26.1 Secondary hyperaldosteronism	0.123	0.876	0.000
E26.0 Primary hyperaldosteronism	0.122	0.878	0.000
E28.9 Ovarian dysfunction, unspecified	0.120	0.880	0.000
E28.8 Other ovarian dysfunction	0.120	0.880	0.000
E28.1 Androgen excess	0.120	0.880	0.000
E28.0 Oestrogen excess	0.120	0.880	0.000
E26.9 Hyperaldosteronism, unspecified	0.120	0.880	0.000
C67.0 Trigone of bladder	0.117	0.883	0.000
E53 Deficiency of other B group vitamins	0.114	0.886	0.000
E34.5 Androgen resistance syndrome	0.113	0.887	0.000
E34.4 Constitutional tall stature	0.113	0.887	0.000
E34.3 Short stature, not elsewhere classified	0.113	0.887	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.113	0.887	0.000
E34.1 Other hypersecretion of intestinal hormones	0.113	0.887	0.000
E34.0 Carcinoid syndrome	0.113	0.887	0.000
E51.9 Thiamine deficiency, unspecified	0.113	0.887	0.000
E51.8 Other manifestations of thiamine deficiency	0.113	0.887	0.000
E51.1 Beriberi	0.113	0.887	0.000
E23.0 Hypopituitarism	0.113	0.887	0.000
E12.9 Without complications	0.112	0.887	0.000
E12.8 With unspecified complications	0.112	0.887	0.000
E12.7 With multiple complications	0.112	0.887	0.000
E12.6 With other specified complications	0.112	0.887	0.000
E12.5 With peripheral circulatory complications	0.112	0.887	0.000
E12.4 With neurological complications	0.112	0.887	0.000
E12.3 With ophthalmic complications	0.112	0.887	0.000
E12.2 With renal complications	0.112	0.887	0.000
E12.1 With ketoacidosis	0.112	0.887	0.000
E12.0 With coma	0.112	0.887	0.000
E13 Other specified diabetes mellitus	0.110	0.889	0.001
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.110	0.890	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.110	0.890	0.000
E23.1 Drug-induced hypopituitarism	0.110	0.890	0.000
E55.0 Rickets, active	0.108	0.892	0.000
E14 Unspecified diabetes mellitus	0.107	0.893	0.000
E29.9 Testicular dysfunction, unspecified	0.106	0.894	0.000
E29.8 Other testicular dysfunction	0.106	0.894	0.000
E29.0 Testicular hyperfunction	0.106	0.894	0.000
E34.9 Endocrine disorder, unspecified	0.106	0.894	0.000
E34.8 Other specified endocrine disorders	0.104	0.896	0.000
E65-E68 Obesity and other hyperalimentation	0.104	0.896	0.000
E15 Nondiabetic hypoglycaemic coma	0.102	0.897	0.000
E44.1 Mild protein-energy malnutrition	0.101	0.899	0.000
E44.0 Moderate protein-energy malnutrition	0.101	0.899	0.000
E21.2 Other hyperparathyroidism	0.101	0.899	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.099	0.901	0.000
E51.2 Wernicke's encephalopathy	0.097	0.902	0.000
E21.4 Other specified disorders of parathyroid gland	0.095	0.904	0.000
E14.6 With other specified complications	0.095	0.905	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.093	0.906	0.000
E22.1 Hyperprolactinaemia	0.092	0.908	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.092	0.908	0.000
E22.8 Other hyperfunction of pituitary gland	0.092	0.908	0.000
Z95.1 Presence of aortocoronary bypass graft	0.092	0.908	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.091	0.909	0.000
E53.9 Vitamin B deficiency, unspecified	0.086	0.914	0.000
E55.9 Vitamin D deficiency, unspecified	0.086	0.914	0.000
E14.4 With neurological complications	0.085	0.915	0.000
E14.0 With coma	0.085	0.915	0.000
E13.3 With ophthalmic complications	0.083	0.916	0.001
E53.1 Pyridoxine deficiency	0.082	0.918	0.000
E53.0 Riboflavin deficiency	0.082	0.918	0.000
E13.8 With unspecified complications	0.079	0.921	0.001
E13.7 With multiple complications	0.079	0.921	0.001
E13.6 With other specified complications	0.079	0.921	0.001
E13.5 With peripheral circulatory complications	0.079	0.921	0.001
E13.4 With neurological complications	0.079	0.921	0.001
E13.2 With renal complications	0.079	0.921	0.001
E13.1 With ketoacidosis	0.079	0.921	0.001
E13.0 With coma	0.079	0.921	0.001
E29.1 Testicular hypofunction	0.077	0.923	0.000
E14.7 With multiple complications	0.077	0.923	0.000
E21.3 Hyperparathyroidism, unspecified	0.076	0.924	0.000
E23.7 Disorder of pituitary gland, unspecified	0.075	0.925	0.000
E67 Other hyperalimentation	0.075	0.925	0.000
E68 Sequelae of hyperalimentation	0.075	0.925	0.000
E23.2 Diabetes insipidus	0.075	0.925	0.000
E14.8 With unspecified complications	0.074	0.926	0.000
E14.3 With ophthalmic complications	0.071	0.929	0.000
E14.2 Withrenal complications	0.070	0.930	0.000
C77.9 Lymph node, unspecified	0.000	0.932	0.068
C77.3 Axillary and upper limb lymph nodes	0.000	0.932	0.068
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.932	0.068
E65 Localised adiposity	0.066	0.933	0.000
C77.1 Intrathoracic lymph nodes	0.000	0.934	0.066
E14.1 With ketoacidosis	0.063	0.937	0.000
E14.5 With peripheral circulatory complications	0.063	0.937	0.000
E10.9 Without complications	0.062	0.938	0.000
E28.2 Polycystic ovarian syndrome	0.061	0.939	0.000
E67.8 Other specified hyperalimentation	0.054	0.946	0.000
E67.3 Hypervitaminosis D	0.054	0.946	0.000
E67.2 Megavitamin-B6 syndrome	0.054	0.946	0.000
E67.1 Hypercarotenaemia	0.054	0.946	0.000
E67.0 Hypervitaminosis A	0.054	0.946	0.000
E16 Other disorders of pancreatic internal secretion	0.054	0.946	0.000
C67.9 Bladder, unspecified	0.053	0.947	0.000
C77.2 Intra-abdominal lymph nodes	0.000	0.947	0.053
E04 Other non-toxic goitre	0.052	0.948	0.000
C77.8 Lymph nodes of multiple regions	0.000	0.951	0.049
C77.0 Lymph nodes of head, face and neck	0.000	0.955	0.045
E22.0 Acromegaly and pituitary gigantism	0.044	0.956	0.001
C77.4 Inguinal and lower limb lymph nodes	0.000	0.956	0.044
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.000	0.961	0.039
E16.9 Disorder of pancreatic internal secretion, unspecified	0.039	0.961	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.039	0.961	0.000
E16.4 Abnormal secretion of gastrin	0.039	0.961	0.000
E16.3 Increased secretion of glucagon	0.039	0.961	0.000
E11 Non-insulin-dependent diabetes mellitus	0.039	0.961	0.000
E04.8 Other specified non-toxic goitre	0.037	0.963	0.000
E11.4 With neurological complications	0.037	0.963	0.000
C79 Secondary malignant neoplasm of other sites	0.000	0.964	0.036
E21.0 Primary hyperparathyroidism	0.035	0.965	0.000
C64-C68 Malignant neoplasms of urinary tract	0.035	0.965	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.966	0.034
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.967	0.033
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.967	0.033
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.967	0.033
E16.0 Drug-induced hypoglycaemia without coma	0.031	0.968	0.000
C79.6 Secondary malignant neoplasm of ovary	0.000	0.969	0.031
E11.5 With peripheral circulatory complications	0.030	0.970	0.000
E16.2 Hypoglycaemia, unspecified	0.029	0.971	0.000
E11.7 With multiple complications	0.028	0.972	0.000
R09.3 Abnormal sputum	0.027	0.973	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.000	0.973	0.027
E16.1 Other hypoglycaemia	0.026	0.973	0.000
C65 Malignant neoplasm of renal pelvis	0.026	0.973	0.000
E11.2 With renal complications	0.026	0.974	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.974	0.026
C68 Malignant neoplasm of other and unspecified urinary organs	0.026	0.974	0.000
Z95.0 Presence of cardiac pacemaker	0.026	0.974	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.975	0.025
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.025	0.975	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.975	0.025
E04.9 Non-toxic goitre, unspecified	0.025	0.975	0.000
E04.0 Non-toxic diffuse goitre	0.025	0.975	0.000
C80 Malignant neoplasm without specification of site	0.000	0.975	0.024
R09.1 Pleurisy	0.024	0.976	0.000
C66 Malignant neoplasm of ureter	0.024	0.976	0.000
R09.2 Respiratory arrest	0.022	0.978	0.000
E13.9 Without complications	0.019	0.978	0.002
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.979	0.021
C80.9 Malignant neoplasm, unspecified	0.000	0.979	0.021
C76.3 Pelvis	0.000	0.979	0.021
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.020	0.979	0.000
E11.8 With unspecified complications	0.020	0.980	0.000
E11.6 With other specified complications	0.020	0.980	0.000
C77.5 Intrapelvic lymph nodes	0.000	0.980	0.020
C76.8 Overlapping lesion of other and ill-defined sites	0.000	0.980	0.019
C76.7 Other ill-defined sites	0.000	0.980	0.019
C76.5 Lower limb	0.000	0.980	0.019
C76.4 Upper limb	0.000	0.980	0.019
C68.0 Urethra	0.019	0.981	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.000	0.981	0.019
C76.2 Abdomen	0.000	0.981	0.019
C68.9 Urinary organ, unspecified	0.019	0.981	0.000
C68.8 Overlapping lesion of urinary organs	0.019	0.981	0.000
C68.1 Paraurethral glands	0.019	0.981	0.000
C76.0 Head, face and neck	0.000	0.981	0.018
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.000	0.981	0.019
E11.3 With ophthalmic complications	0.019	0.981	0.000
E11.1 With ketoacidosis	0.018	0.981	0.000
C78.7 Secondary malignant neoplasm of liver	0.000	0.982	0.018
C76.1 Thorax	0.000	0.982	0.018
S12.20 Fracture of other specified cervical vertebra (closed)	0.018	0.982	0.000
R09.0 Asphyxia	0.018	0.982	0.000
E11.0 With coma	0.017	0.982	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.000	0.984	0.016
C78.2 Secondary malignant neoplasm of pleura	0.000	0.984	0.016
S12.2 Fracture of other specified cervical vertebra	0.015	0.985	0.000
S52.00 Fracture of upper end of ulna (closed)	0.014	0.986	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.986	0.014
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.986	0.014
E66 Obesity	0.013	0.987	0.000
S12 Fracture of neck	0.013	0.987	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.000	0.987	0.013
E04.1 Non-toxic single thyroid nodule	0.013	0.987	0.000
E14.9 Without complications	0.013	0.987	0.000
I10 Essential (primary) hypertension	0.012	0.988	0.000
C79.2 Secondary malignant neoplasm of skin	0.000	0.988	0.012
S12.9 Fracture of neck, part unspecified	0.012	0.988	0.000
E04.2 Non-toxic multinodular goitre	0.011	0.989	0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.011	0.989	0.000
S12.21 Fracture of other specified cervical vertebra (open)	0.011	0.989	0.000
S12.1 Fracture of second cervical vertebra	0.011	0.989	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.011	0.989	0.000
E53.8 Deficiency of other specified B group vitamins	0.010	0.989	0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.010	0.990	0.000
E66.1 Drug-induced obesity	0.010	0.990	0.000
S12.8 Fracture of other parts of neck	0.010	0.990	0.000
S12.0 Fracture of first cervical vertebra	0.010	0.990	0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.010	0.990	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.010	0.990	0.000
R16.1 Splenomegaly, not elsewhere classified	0.010	0.990	0.000
E66.0 Obesity due to excess calories	0.009	0.990	0.000
S12.7 Multiple fractures of cervical spine	0.009	0.991	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.009	0.991	0.000
S10-S19 Injuries to the neck	0.009	0.991	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.009	0.991	0.000
S12.91 Fracture of neck, part unspecified (open)	0.009	0.991	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.008	0.991	0.000
S13.4 Sprain and strain of cervical spine	0.008	0.992	0.000
S12.11 Fracture of second cervical vertebra (open)	0.008	0.992	0.000
S52.0 Fracture of upper end of ulna	0.008	0.992	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.008	0.992	0.000
M93.9 Osteochondropathy, unspecified	0.000	0.992	0.008
S11 Open wound of neck	0.008	0.992	0.000
R41.0 Disorientation, unspecified	0.008	0.992	0.000
S12.01 Fracture of first cervical vertebra (open)	0.007	0.993	0.000
S12.00 Fracture of first cervical vertebra (closed)	0.007	0.993	0.000
S12.81 Fracture of other parts of neck (open)	0.007	0.993	0.000
S12.80 Fracture of other parts of neck (closed)	0.007	0.993	0.000
I10-I15 Hypertensive diseases	0.007	0.993	0.000
S13.1 Dislocation of cervical vertebra	0.007	0.993	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.007	0.993	0.000
S12.71 Multiple fractures of cervical spine (open)	0.007	0.993	0.000
S14 Injury of nerves and spinal cord at neck level	0.007	0.993	0.000
S17 Crushing injury of neck	0.007	0.993	0.000
S15 Injury of blood vessels at neck level	0.007	0.993	0.000
S18 Traumatic amputation at neck level	0.007	0.993	0.000
S16 Injury of muscle and tendon at neck level	0.007	0.993	0.000
S11.9 Open wound of neck, part unspecified	0.007	0.993	0.000
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.007	0.993	0.000
S52.01 Fracture of upper end of ulna (open)	0.007	0.993	0.000
S11.7 Multiple open wounds of neck	0.007	0.993	0.000
I12 Hypertensive renal disease	0.007	0.993	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.006	0.993	0.000
M06.9 Rheumatoid arthritis, unspecified	0.007	0.993	0.000
S13.5 Sprain and strain of thyroid region	0.006	0.993	0.000
S13.3 Multiple dislocations of neck	0.006	0.993	0.000
S13.2 Dislocation of other and unspecified parts of neck	0.006	0.993	0.000
S13.0 Traumatic rupture of cervical intervertebral disk	0.006	0.993	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.006	0.994	0.000
S10 Superficial injury of neck	0.006	0.994	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.006	0.994	0.000
I12.9 Hypertensive renal disease without renal failure	0.006	0.994	0.000
S11.8 Open wound of other parts of neck	0.006	0.994	0.000
S11.2 Open wound involving pharynx and cervical oesophagus	0.006	0.994	0.000
S11.1 Open wound involving thyroid gland	0.006	0.994	0.000
S11.0 Open wound involving larynx and trachea	0.006	0.994	0.000
I50.9 Heart failure, unspecified	0.000	0.994	0.006
I13 Hypertensive heart and renal disease	0.006	0.994	0.000
I15 Secondary hypertension	0.006	0.994	0.000
S14.3 Injury of brachial plexus	0.006	0.994	0.000
M06.4 Inflammatory polyarthropathy	0.006	0.994	0.000
M07.3 Other psoriatic arthropathies	0.006	0.994	0.000
M06 Other rheumatoid arthritis	0.006	0.994	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.994	0.005
K60.2 Anal fissure, unspecified	0.006	0.994	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.005	0.994	0.000
C78.0 Secondary malignant neoplasm of lung	0.000	0.994	0.006
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.005	0.995	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.995	0.005
M07.39 Other psoriatic arthropathies (Site unspecified)	0.005	0.995	0.000
I12.0 Hypertensive renal disease with renal failure	0.005	0.995	0.000
S14.6 Injury of other and unspecified nerves of neck	0.005	0.995	0.000
S14.5 Injury of cervical sympathetic nerves	0.005	0.995	0.000
S14.4 Injury of peripheral nerves of neck	0.005	0.995	0.000
S14.2 Injury of nerve root of cervical spine	0.005	0.995	0.000
S14.0 Concussion and oedema of cervical spinal cord	0.005	0.995	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.005	0.995	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.005	0.995	0.000
S15.9 Injury of unspecified blood vessel at neck level	0.005	0.995	0.000
S15.8 Injury of other blood vessels at neck level	0.005	0.995	0.000
S15.7 Injury of multiple blood vessels at neck level	0.005	0.995	0.000
S15.3 Injury of internal jugular vein	0.005	0.995	0.000
S15.2 Injury of external jugular vein	0.005	0.995	0.000
S15.1 Injury of vertebral artery	0.005	0.995	0.000
S15.0 Injury of carotid artery	0.005	0.995	0.000
S17.9 Crushing injury of neck, part unspecified	0.005	0.995	0.000
S17.8 Crushing injury of other parts of neck	0.005	0.995	0.000
S17.0 Crushing injury of larynx and traches	0.005	0.995	0.000
S19 Other and unspecified injuries of neck	0.005	0.995	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.005	0.995	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.005	0.995	0.000
S14.1 Other and unspecified injuries of cervical spinal cord	0.005	0.995	0.000
I15.0 Renovascular hypertension	0.005	0.995	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.005	0.995	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.005	0.995	0.000
I15.9 Seconday hypertension, unspecified	0.005	0.995	0.000
S10.7 Multiple superficial injuries of neck	0.005	0.995	0.000
S10.0 Contusion of throat	0.005	0.995	0.000
M07 Psoriatic and enteropathic arthropathies	0.005	0.995	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.005	0.995	0.000
S10.8 Superficial injury of other parts of neck	0.005	0.995	0.000
S10.9 Superficial injury of neck, part unspecified	0.004	0.995	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.004	0.995	0.000
M05 Seropositive rheumatoid arthritis	0.005	0.995	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.004	0.995	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.004	0.996	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.004	0.996	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.004	0.996	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.004	0.996	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.004	0.996	0.000
I15.8 Other secondary hypertension	0.004	0.996	0.000
I15.2 Hypertension secondary to endocrine disorders	0.004	0.996	0.000
M35.0 Sicca syndrome [Sjogren]	0.004	0.996	0.000
S10.1 Other and unspecified superficial injuries of throat	0.004	0.996	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.004	0.996	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.004	0.996	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.004	0.996	0.000
S32.30 Fracture of ilium (closed)	0.000	0.996	0.004
M06.8 Other specified rheumatoid arthritis	0.004	0.996	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.004	0.996	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.004	0.996	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.004	0.996	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.004	0.996	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.004	0.996	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.004	0.996	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.004	0.996	0.000
M07.38 Other psoriatic arthropathies (Other)	0.004	0.996	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.004	0.996	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.004	0.996	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.004	0.996	0.000
M06.2 Rheumatoid bursitis	0.004	0.996	0.000
M06.1 Adult-onset Still's disease	0.004	0.996	0.000
M05-M14 Inflammatory polyarthropathies	0.004	0.996	0.000
D64.8 Other specified anaemias	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations