TreeWAS – Variant ID: rs10757269

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	1.000	0.000	0.000
H40.9 Glaucoma, unspecified	1.000	0.000	0.000
I20.9 Angina pectoris, unspecified	1.000	0.000	0.000
I20.0 Unstable angina	1.000	0.000	0.000
I21.9 Acute myocardial infarction, unspecified	1.000	0.000	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	1.000	0.000	0.000
I25.9 Chronic ischaemic heart disease, unspecified	1.000	0.000	0.000
I25.8 Other forms of chronic ischaemic heart disease	1.000	0.000	0.000
I25.2 Old myocardial infarction	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
I73.9 Peripheral vascular disease, unspecified	1.000	0.000	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	1.000	0.000	0.000
Z92.2 Personal history of long-term (current) use of other medicaments	1.000	0.000	0.000
Z95.5 Presence of coronary angioplasty implant and graft	1.000	0.000	0.000
Z95.1 Presence of aortocoronary bypass graft	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I21 Acute myocardial infarction	1.000	0.000	0.000
I20 Angina pectoris	1.000	0.000	0.000
Z95 Presence of cardiac and vascular implants and grafts	1.000	0.000	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000	0.000
I21.4 Acute subendocardial myocardial infarction	1.000	0.000	0.000
I77.1 Stricture of artery	1.000	0.000	0.000
H40 Glaucoma	1.000	0.000	0.000
I77 Other disorders of arteries and arterioles	1.000	0.000	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	1.000	0.000	0.000
I22 Subsequent myocardial infarction	1.000	0.000	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	1.000	0.000	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	1.000	0.000	0.000
I73 Other peripheral vascular diseases	1.000	0.000	0.000
I50.1 Left ventricular failure	1.000	0.000	0.000
I24 Other acute ischaemic heart diseases	1.000	0.000	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	1.000	0.000	0.000
I74 Arterial embolism and thrombosis	1.000	0.000	0.000
I71 Aortic aneurysm and dissection	0.999	0.001	0.000
H40.1 Primary open-angle glaucoma	0.999	0.001	0.000
I30-I52 Other forms of heart disease	0.999	0.001	0.000
I50 Heart failure	0.999	0.001	0.000
I60-I69 Cerebrovascular diseases	0.998	0.002	0.000
Y83.2 Surgical operation with anastomosis, bypass or graft	0.997	0.003	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.997	0.003	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.996	0.004	0.000
I24.8 Other forms of acute ischaemic heart disease	0.996	0.004	0.000
I65.2 Occlusion and stenosis of carotid artery	0.996	0.004	0.000
I46 Cardiac arrest	0.995	0.005	0.000
I72 Other aneurysm	0.995	0.005	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.995	0.005	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.991	0.009	0.000
I70 Atherosclerosis	0.991	0.009	0.000
H26.9 Cataract, unspecified	0.991	0.009	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.987	0.013	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.985	0.015	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.984	0.016	0.000
H26 Other cataract	0.982	0.018	0.000
I20.8 Other forms of angina pectoris	0.981	0.019	0.000
H40-H42 Glaucoma	0.980	0.020	0.000
H25-H28 Disorders of lens	0.979	0.021	0.000
I46.0 Cardiac arrest with successful resuscitation	0.972	0.028	0.000
I51 Complications and ill-defined descriptions of heart disease	0.971	0.029	0.000
Chapter VII Diseases of the eye and adnexa	0.965	0.035	0.000
I46.9 Cardiac arrest, unspecified	0.964	0.036	0.000
I25.5 Ischaemic cardiomyopathy	0.963	0.037	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.959	0.041	0.000
I51.7 Cardiomegaly	0.958	0.042	0.000
H25 Senile cataract	0.956	0.044	0.000
I72.3 Aneurysm of iliac artery	0.951	0.049	0.000
H25.1 Senile nuclear cataract	0.946	0.054	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.945	0.055	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.945	0.055	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.944	0.056	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.939	0.061	0.000
K62.1 Rectal polyp	0.000	0.064	0.936
Z95.3 Presence of xenogenic heart valve	0.934	0.066	0.000
E78.5 Hyperlipidaemia, unspecified	0.926	0.074	0.000
K62 Other diseases of anus and rectum	0.000	0.080	0.920
I60 Subarachnoid haemorrhage	0.917	0.083	0.000
I72.4 Aneurysm of artery of lower extremity	0.914	0.086	0.000
H40.8 Other glaucoma	0.913	0.087	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.911	0.089	0.000
K62.4 Stenosis of anus and rectum	0.000	0.097	0.903
K62.2 Anal prolapse	0.000	0.098	0.902
I35 Nonrheumatic aortic valve disorders	0.899	0.101	0.000
H30-H36 Disorders of choroid and retina	0.892	0.108	0.000
E78.4 Other hyperlipidaemia	0.887	0.113	0.000
H34 Retinal vascular occlusions	0.881	0.119	0.000
I51.6 Cardiovascular disease, unspecified	0.874	0.126	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.872	0.128	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.869	0.131	0.000
H34.8 Other retinal vascular occlusions	0.869	0.131	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.864	0.136	0.000
K62.8 Other specified diseases of anus and rectum	0.000	0.140	0.860
H26.2 Complicated cataract	0.858	0.142	0.000
I25.3 Aneurysm of heart	0.858	0.142	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.855	0.145	0.000
Z82.3 Family history of stroke	0.853	0.147	0.000
H25.8 Other senile cataract	0.852	0.148	0.000
I72.9 Aneurysm of unspecified site	0.832	0.167	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.830	0.170	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.826	0.174	0.000
I74.5 Embolism and thrombosis of iliac artery	0.826	0.174	0.000
I72.1 Aneurysm of artery of upper extremity	0.814	0.186	0.000
I63 Cerebral infarction	0.812	0.188	0.000
I73.8 Other specified peripheral vascular diseases	0.808	0.192	0.000
H40.0 Glaucoma suspect	0.807	0.193	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.806	0.194	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.798	0.202	0.000
I22.8 Subsequent myocardial infarction of other sites	0.795	0.205	0.000
I69 Sequelae of cerebrovascular disease	0.794	0.206	0.000
H40.4 Glaucoma secondary to eye inflammation	0.790	0.209	0.000
I65.1 Occlusion and stenosis of basilar artery	0.789	0.211	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.777	0.223	0.000
K62.0 Anal polyp	0.000	0.228	0.772
I73.1 Thromboangiitis obliterans [Buerger]	0.766	0.234	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.765	0.235	0.000
I69.3 Sequelae of cerebral infarction	0.764	0.236	0.000
I72.2 Aneurysm of renal artery	0.763	0.237	0.000
I25.4 Coronary artery aneurysm	0.759	0.241	0.000
H53-H54 Visual disturbances and blindness	0.758	0.242	0.000
I74.8 Embolism and thrombosis of other arteries	0.757	0.243	0.000
I51.4 Myocarditis, unspecified	0.754	0.246	0.000
I72.0 Aneurysm of carotid artery	0.753	0.247	0.000
H35 Other retinal disorders	0.751	0.249	0.000
I51.5 Myocardial degeneration	0.747	0.253	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.741	0.259	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.740	0.260	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.735	0.265	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.734	0.266	0.000
I33 Acute and subacute endocarditis	0.730	0.270	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.729	0.271	0.000
I35.1 Aortic (valve) insufficiency	0.722	0.278	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.721	0.279	0.000
I25.6 Silent myocardial ischaemia	0.718	0.281	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.718	0.282	0.000
I72.8 Aneurysm of other specified arteries	0.717	0.283	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.717	0.283	0.000
H40.6 Glaucoma secondary to drugs	0.717	0.283	0.000
I77.5 Necrosis of artery	0.717	0.283	0.000
I77.4 Coeliac artery compression syndrome	0.717	0.283	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.717	0.283	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.717	0.283	0.000
I52 Other heart disorders in diseases classified elsewhere	0.716	0.284	0.000
I48 Atrial fibrillation and flutter	0.716	0.284	0.000
I41 Myocarditis in diseases classified elsewhere	0.716	0.284	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.716	0.284	0.000
I32 Pericarditis in diseases classified elsewhere	0.716	0.284	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.714	0.286	0.000
H40.3 Glaucoma secondary to eye trauma	0.714	0.286	0.000
I77.3 Arterial fibromuscular dysplasia	0.714	0.286	0.000
I46.1 Sudden cardiac death, so described	0.714	0.286	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.714	0.286	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.714	0.286	0.000
H40.5 Glaucoma secondary to other eye disorders	0.714	0.286	0.000
Z95.0 Presence of cardiac pacemaker	0.713	0.287	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.712	0.288	0.000
H53.8 Other visual disturbances	0.710	0.290	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.709	0.291	0.000
I70.1 Atherosclerosis of renal artery	0.707	0.293	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.707	0.293	0.000
H53 Visual disturbances	0.707	0.293	0.000
I62 Other nontraumatic intracranial haemorrhage	0.705	0.295	0.000
H26.3 Drug-induced cataract	0.703	0.297	0.000
H42 Glaucoma in diseases classified elsewhere	0.702	0.298	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.696	0.303	0.000
H35.7 Separation of retinal layers	0.691	0.309	0.000
I00-I02 Acute rheumatic fever	0.691	0.309	0.000
I70.8 Atherosclerosis of other arteries	0.689	0.311	0.000
I70.9 Generalised and unspecified atherosclerosis	0.688	0.312	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.687	0.313	0.000
H25.2 Senile cataract, morgagnian type	0.686	0.314	0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.682	0.318	0.000
I37 Pulmonary valve disorders	0.681	0.319	0.000
I63.8 Other cerebral infarction	0.680	0.320	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.680	0.320	0.000
H34.1 Central retinal artery occlusion	0.677	0.322	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.677	0.323	0.000
E78.3 Hyperchylomicronaemia	0.677	0.323	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.673	0.327	0.000
H34.2 Other retinal artery occlusions	0.672	0.328	0.000
H35.2 Other proliferative retinopathy	0.665	0.335	0.000
H26.1 Traumatic cataract	0.662	0.338	0.000
H26.0 Infantile, juvenile and presenile cataract	0.661	0.339	0.000
H10-H13 Disorders of conjunctiva	0.659	0.341	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.658	0.342	0.000
E78.8 Other disorders of lipoprotein metabolism	0.658	0.342	0.000
I23 Certain current complications following acute myocardial infarction	0.654	0.346	0.000
I79.1 Aortitis in diseases classified elsewhere	0.653	0.346	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.653	0.346	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.652	0.348	0.000
H34.9 Retinal vascular occlusion, unspecified	0.651	0.349	0.000
H35.5 Hereditary retinal dystrophy	0.649	0.351	0.000
I20.1 Angina pectoris with documented spasm	0.646	0.354	0.000
E78.6 Lipoprotein deficiency	0.642	0.357	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.641	0.359	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.641	0.359	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.640	0.360	0.000
I77.0 Arteriovenous fistula, acquired	0.640	0.360	0.000
I50.0 Congestive heart failure	0.638	0.362	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.636	0.364	0.000
H26.8 Other specified cataract	0.633	0.367	0.000
E78.1 Pure hyperglyceridaemia	0.632	0.368	0.000
H34.0 Transient retinal artery occlusion	0.632	0.368	0.000
I63.9 Cerebral infarction, unspecified	0.632	0.368	0.000
H50 Other strabismus	0.631	0.369	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.629	0.371	0.000
Z95.2 Presence of prosthetic heart valve	0.628	0.372	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.626	0.374	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.622	0.378	0.000
I36 Nonrheumatic tricuspid valve disorders	0.620	0.380	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.618	0.381	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.618	0.382	0.000
I60.8 Other subarachnoid haemorrhage	0.610	0.390	0.000
I30 Acute pericarditis	0.609	0.391	0.000
I40 Acute myocarditis	0.606	0.394	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.599	0.400	0.000
I10-I15 Hypertensive diseases	0.599	0.401	0.000
H30 Chorioretinal inflammation	0.596	0.404	0.000
I77.2 Rupture of artery	0.591	0.408	0.000
H35.9 Retinal disorder, unspecified	0.585	0.415	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.582	0.418	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.582	0.418	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.582	0.418	0.000
I33.9 Acute endocarditis, unspecified	0.579	0.421	0.000
H25.0 Senile incipient cataract	0.579	0.421	0.000
E78.2 Mixed hyperlipidaemia	0.579	0.421	0.000
H50.0 Convergent concomitant strabismus	0.578	0.422	0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.577	0.423	0.000
I67 Other cerebrovascular diseases	0.573	0.427	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.572	0.428	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.572	0.428	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.569	0.430	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.569	0.431	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.566	0.434	0.000
I70.0 Atherosclerosis of aorta	0.564	0.436	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.564	0.436	0.000
I24.1 Dressler's syndrome	0.561	0.439	0.000
H35.6 Retinal haemorrhage	0.560	0.440	0.000
H31 Other disorders of choroid	0.558	0.442	0.000
Z82.2 Family history of deafness and hearing loss	0.558	0.442	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.557	0.443	0.000
I05-I09 Chronic rheumatic heart diseases	0.557	0.443	0.000
I35.9 Aortic valve disorder, unspecified	0.555	0.444	0.000
H11 Other disorders of conjunctiva	0.554	0.446	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.547	0.452	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.546	0.454	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.544	0.456	0.000
I62.1 Nontraumatic extradural haemorrhage	0.543	0.457	0.000
H50.9 Strabismus, unspecified	0.541	0.459	0.000
H35.1 Retinopathy of prematurity	0.538	0.461	0.000
E11.9 Without complications	0.534	0.466	0.000
I35.8 Other aortic valve disorders	0.534	0.466	0.000
Z82.1 Family history of blindness and visual loss	0.532	0.467	0.000
I34 Nonrheumatic mitral valve disorders	0.531	0.469	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.527	0.473	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.527	0.473	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.527	0.473	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.527	0.473	0.000
I37.0 Pulmonary valve stenosis	0.526	0.474	0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.524	0.476	0.000
I11 Hypertensive heart disease	0.516	0.484	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.514	0.486	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.514	0.486	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.514	0.486	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.514	0.486	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.514	0.486	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.514	0.486	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.514	0.486	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.514	0.486	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.514	0.486	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.514	0.486	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.514	0.486	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.514	0.486	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.514	0.486	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.514	0.486	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.514	0.486	0.000
I48.4 Atypical atrial flutter	0.514	0.486	0.000
I48.3 Typical atrial flutter	0.514	0.486	0.000
I48.2 Chronic atrial fibrillation	0.514	0.486	0.000
I48.1 Persistent atrial fibrillation	0.514	0.486	0.000
I48.0 Paroxysmal atrial fibrillation	0.514	0.486	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.514	0.486	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.514	0.486	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.514	0.486	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.513	0.487	0.000
I51.9 Heart disease, unspecified	0.513	0.487	0.000
K62.6 Ulcer of anus and rectum	0.000	0.492	0.508
K62.3 Rectal prolapse	0.000	0.493	0.507
I70.11 Atherosclerosis of renal artery (with gangrene)	0.507	0.493	0.000
H53.6 Night blindness	0.507	0.493	0.000
H53.5 Colour vision deficiencies	0.507	0.493	0.000
H53.3 Other disorders of binocular vision	0.507	0.493	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.504	0.496	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.504	0.496	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.504	0.496	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.502	0.498	0.000
K62.5 Haemorrhage of anus and rectum	0.000	0.502	0.498
H50.4 Other and unspecified heterotropia	0.498	0.502	0.000
I13 Hypertensive heart and renal disease	0.498	0.502	0.000
H50.5 Heterophoria	0.497	0.503	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.497	0.503	0.000
T82.3 Mechanical complication of other vascular grafts	0.497	0.503	0.000
I02 Rheumatic chorea	0.496	0.504	0.000
I01 Rheumatic fever with heart involvement	0.496	0.504	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.494	0.506	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.493	0.506	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.492	0.508	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.491	0.508	0.000
I37.9 Pulmonary valve disorder, unspecified	0.488	0.512	0.000
I37.8 Other pulmonary valve disorders	0.488	0.512	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.488	0.512	0.000
H53.2 Diplopia	0.485	0.515	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.485	0.515	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.483	0.517	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.483	0.517	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.483	0.517	0.000
H53.0 Amblyopia ex anopsia	0.483	0.517	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.481	0.518	0.000
H31.9 Disorder of choroid, unspecified	0.481	0.519	0.000
I71.0 Dissection of aorta [any part]	0.480	0.520	0.000
I51.0 Cardiac septal defect, acquired	0.480	0.520	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.472	0.528	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.472	0.528	0.000
I30.8 Other forms of acute pericarditis	0.471	0.528	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.471	0.529	0.000
I00 Rheumatic fever without mention of heart involvement	0.470	0.530	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.469	0.531	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.469	0.531	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.469	0.531	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.469	0.531	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.469	0.531	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.469	0.531	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.469	0.531	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.466	0.534	0.000
I33.0 Acute and subacute infective endocarditis	0.466	0.534	0.000
I07 Rheumatic tricuspid valve diseases	0.463	0.537	0.000
H11.3 Conjunctival haemorrhage	0.461	0.539	0.000
T82.1 Mechanical complication of cardiac electronic device	0.460	0.540	0.000
H50.1 Divergent concomitant strabismus	0.460	0.540	0.000
H28.8 Other disorders of lens in diseases classified elsewhere	0.459	0.540	0.000
H28.2 Cataract in other diseases classified elsewhere	0.459	0.540	0.000
H28.1 Cataract in other endocrine, nutritional and metabolic diseases	0.459	0.540	0.000
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.459	0.541	0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.459	0.541	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.457	0.543	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.455	0.545	0.000
I61 Intracerebral haemorrhage	0.454	0.546	0.000
H36 Retinal disorders in diseases classified elsewhere	0.454	0.546	0.000
I84.8 Unspecified haemorrhoids with other complications	0.000	0.546	0.454
H50.3 Intermittent heterotropia	0.452	0.548	0.000
H35.3 Degeneration of macula and posterior pole	0.452	0.548	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.445	0.555	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.445	0.555	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.445	0.555	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.445	0.555	0.000
H51 Other disorders of binocular movement	0.443	0.556	0.000
I68.0 Cerebral amyloid angiopathy	0.440	0.560	0.000
H50.2 Vertical strabismus	0.440	0.560	0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.437	0.563	0.000
H11.9 Disorder of conjunctiva, unspecified	0.437	0.563	0.000
I84 Haemorrhoids	0.000	0.563	0.437
I30.0 Acute nonspecific idiopathic pericarditis	0.436	0.563	0.000
H40.2 Primary angle-closure glaucoma	0.436	0.564	0.000
I40.8 Other acute myocarditis	0.434	0.565	0.000
I40.1 Isolated myocarditis	0.434	0.565	0.000
H11.1 Conjunctival degenerations and deposits	0.434	0.566	0.000
I84.4 External haemorrhoids with other complications	0.000	0.568	0.432
H27 Other disorders of lens	0.429	0.571	0.000
H30.8 Other chorioretinal inflammations	0.427	0.572	0.000
H30.2 Posterior cyclitis	0.427	0.572	0.000
H30.1 Disseminated chorioretinal inflammation	0.427	0.572	0.000
H30.0 Focal chorioretinal inflammation	0.427	0.572	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.426	0.574	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.420	0.580	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.417	0.583	0.000
I08 Multiple valve diseases	0.416	0.584	0.000
H55-H59 Other disorders of eye and adnexa	0.412	0.588	0.000
I67.9 Cerebrovascular disease, unspecified	0.412	0.588	0.000
I67.5 Moyamoya disease	0.411	0.589	0.000
I67.4 Hypertensive encephalopathy	0.411	0.589	0.000
I67.3 Progressive vascular leukoencephalopathy	0.411	0.589	0.000
I84.2 Internal haemorrhoids without complication	0.000	0.589	0.411
C71.9 Brain, unspecified	0.000	0.590	0.410
I13.9 Hypertensive heart and renal disease, unspecified	0.408	0.592	0.000
I23.8 Other current complications following acute myocardial infarction	0.406	0.594	0.000
C71 Malignant neoplasm of brain	0.000	0.594	0.406
H35.4 Peripheral retinal degeneration	0.405	0.594	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.404	0.595	0.000
H31.4 Choroidal detachment	0.400	0.600	0.000
H31.2 Hereditary choroidal dystrophy	0.400	0.600	0.000
H28.0 Diabetic cataract	0.398	0.601	0.000
I35.0 Aortic (valve) stenosis	0.398	0.602	0.000
I37.1 Pulmonary valve insufficiency	0.397	0.602	0.000
H31.3 Choroidal haemorrhage and rupture	0.397	0.603	0.000
I07.1 Tricuspid insufficiency	0.396	0.604	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.396	0.604	0.000
I40.9 Acute myocarditis, unspecified	0.395	0.605	0.000
H11.2 Conjunctival scars	0.395	0.605	0.000
I84.6 Residual haemorrhoidal skin tags	0.000	0.606	0.394
H50.6 Mechanical strabismus	0.394	0.606	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.393	0.607	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.389	0.611	0.000
K62.7 Radiation proctitis	0.000	0.615	0.385
I13.1 Hypertensive heart and renal disease with renal failure	0.385	0.615	0.000
H30.9 Chorioretinal inflammation, unspecified	0.384	0.616	0.000
I30.9 Acute pericarditis, unspecified	0.384	0.616	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.383	0.617	0.000
I08.8 Other multiple valve diseases	0.379	0.621	0.000
I40.0 Infective myocarditis	0.377	0.623	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.375	0.624	0.001
I09 Other rheumatic heart diseases	0.374	0.626	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.369	0.631	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.365	0.635	0.000
C71.8 Overlapping lesion of brain	0.000	0.637	0.363
H10 Conjunctivitis	0.362	0.638	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.357	0.643	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.357	0.643	0.000
H52 Disorders of refraction and accommodation	0.356	0.643	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.356	0.644	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.355	0.644	0.000
I01.8 Other acute rheumatic heart disease	0.355	0.644	0.000
I01.2 Acute rheumatic myocarditis	0.355	0.644	0.000
I01.1 Acute rheumatic endocarditis	0.355	0.644	0.000
I01.0 Acute rheumatic pericarditis	0.355	0.644	0.000
I02.9 Rheumatic chorea without heart involvement	0.355	0.644	0.000
I02.0 Rheumatic chorea with heart involvement	0.355	0.644	0.000
C71.2 Temporal lobe	0.000	0.645	0.355
I69.1 Sequelae of intracerebral haemorrhage	0.352	0.648	0.000
H26.4 After-cataract	0.351	0.649	0.000
C71.0 Cerebrum, except lobes and ventricles	0.000	0.651	0.349
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.349	0.651	0.000
H31.1 Choroidal degeneration	0.348	0.652	0.000
I15 Secondary hypertension	0.345	0.655	0.000
D36.1 Peripheral nerves and autonomic nervous system	0.000	0.657	0.343
C71.3 Parietal lobe	0.000	0.657	0.343
I77.8 Other specified disorders of arteries and arterioles	0.342	0.658	0.001
C71.1 Frontal lobe	0.000	0.659	0.341
I30.1 Infective pericarditis	0.339	0.660	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.340	0.660	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.339	0.661	0.000
I45 Other conduction disorders	0.339	0.661	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.336	0.664	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.336	0.664	0.000
I47 Paroxysmal tachycardia	0.335	0.665	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.334	0.666	0.000
H50.8 Other specified strabismus	0.332	0.667	0.000
I07.9 Tricuspid valve disease, unspecified	0.332	0.668	0.000
I07.8 Other tricuspid valve diseases	0.332	0.668	0.000
I07.2 Tricuspid stenosis with insufficiency	0.332	0.668	0.000
I07.0 Tricuspid stenosis	0.332	0.668	0.000
I84.9 Unspecified haemorrhoids without complication	0.000	0.671	0.329
H31.8 Other specified disorders of choroid	0.327	0.673	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.325	0.674	0.000
H11.8 Other specified disorders of conjunctiva	0.324	0.676	0.000
Z95.4 Presence of other heart-valve replacement	0.324	0.676	0.000
I44 Atrioventricular and left bundle-branch block	0.323	0.677	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.322	0.678	0.000
I08.9 Multiple valve disease, unspecified	0.321	0.679	0.000
I10 Essential (primary) hypertension	0.320	0.680	0.000
I84.7 Unspecified thrombosed haemorrhoids	0.000	0.681	0.319
H21 Other disorders of iris and ciliary body	0.319	0.681	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.318	0.681	0.001
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.319	0.681	0.000
H51.9 Disorder of binocular movement, unspecified	0.318	0.682	0.000
H51.8 Other specified disorders of binocular movement	0.318	0.682	0.000
H51.1 Convergence insufficiency and excess	0.318	0.682	0.000
H51.0 Palsy of conjugate gaze	0.318	0.682	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.317	0.683	0.000
I06 Rheumatic aortic valve diseases	0.317	0.683	0.000
H31.0 Chorioretinal scars	0.313	0.687	0.000
H10.8 Other conjunctivitis	0.312	0.688	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.308	0.692	0.001
H27.9 Disorder of lens, unspecified	0.308	0.692	0.000
H52.1 Myopia	0.308	0.692	0.000
I78 Diseases of capillaries	0.307	0.692	0.000
I45.9 Conduction disorder, unspecified	0.307	0.693	0.000
H15 Disorders of sclera	0.307	0.693	0.000
I44.0 Atrioventricular block, first degree	0.306	0.694	0.000
C71.7 Brain stem	0.000	0.696	0.304
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.304	0.696	0.000
H13.8 Other disorders of conjunctiva in diseases classified elsewhere	0.299	0.701	0.000
H13.2 Conjunctivitis in other diseases classified elsewhere	0.299	0.701	0.000
H13.0 Filarial infection of conjunctiva	0.299	0.701	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.297	0.703	0.000
I84.5 External haemorrhoids without complication	0.000	0.704	0.296
I34.2 Nonrheumatic mitral (valve) stenosis	0.293	0.707	0.000
C71.4 Occipital lobe	0.000	0.707	0.293
C71.6 Cerebellum	0.000	0.709	0.291
C71.5 Cerebral ventricle	0.000	0.709	0.291
H21.5 Other adhesions and disruptions of iris and ciliary body	0.289	0.711	0.000
H35.0 Background retinopathy and retinal vascular changes	0.288	0.712	0.000
H13.3 Ocular pemphigoid	0.286	0.713	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.281	0.718	0.000
I67.2 Cerebral atherosclerosis	0.281	0.719	0.000
H27.1 Dislocation of lens	0.278	0.722	0.000
H51.2 Internuclear ophthalmoplegia	0.276	0.724	0.000
H52.0 Hypermetropia	0.275	0.725	0.000
H10.5 Blepharoconjunctivitis	0.269	0.731	0.000
H17 Corneal scars and opacities	0.269	0.731	0.000
I09.8 Other specified rheumatic heart diseases	0.268	0.732	0.000
I09.2 Chronic rheumatic pericarditis	0.268	0.732	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations