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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1077394
log Bayes Factor = 76.4756
Chromosome 6   position 31,610,384  (GRCh37) Explore rs1077394 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.001 0.999
L40.9 Psoriasis, unspecified
0.000 0.010 0.990
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.019 0.981
E14 Unspecified diabetes mellitus
0.000 0.023 0.977
E10.1 With ketoacidosis
0.000 0.023 0.977
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.024 0.976
E07 Other disorders of thyroid
0.000 0.030 0.970
G35-G37 Demyelinating diseases of the central nervous system
0.964 0.036 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.040 0.960
G37 Other demyelinating diseases of central nervous system
0.957 0.043 0.000
E83.1 Disorders of iron metabolism
0.948 0.052 0.000
E14.9 Without complications
0.000 0.058 0.942
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.060 0.940
E16.2 Hypoglycaemia, unspecified
0.000 0.061 0.939
E05.9 Thyrotoxicosis, unspecified
0.000 0.068 0.932
E14.3 With ophthalmic complications
0.000 0.070 0.930
E07.9 Disorder of thyroid, unspecified
0.000 0.077 0.923
G37.9 Demyelinating disease of central nervous system, unspecified
0.915 0.085 0.000
E11.3 With ophthalmic complications
0.000 0.096 0.904
E10.4 With neurological complications
0.000 0.109 0.891
G37.8 Other specified demyelinating diseases of central nervous system
0.878 0.122 0.000
L40 Psoriasis
0.000 0.152 0.848
E07.8 Other specified disorders of thyroid
0.000 0.156 0.844
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.843 0.157 0.000
E10.8 With unspecified complications
0.000 0.158 0.842
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.173 0.827
L40.5 Arthropathic psoriasis
0.000 0.196 0.804
E16.1 Other hypoglycaemia
0.000 0.209 0.791
E11.1 With ketoacidosis
0.000 0.209 0.791
E10.0 With coma
0.000 0.242 0.758
E11.6 With other specified complications
0.000 0.246 0.754
E03.8 Other specified hypothyroidism
0.000 0.252 0.748
E11.2 With renal complications
0.000 0.257 0.743
E78.0 Pure hypercholesterolaemia
0.000 0.262 0.738
E14.1 With ketoacidosis
0.000 0.268 0.732
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.274 0.726
E14.8 With unspecified complications
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.290 0.710
E05.5 Thyroid crisis or storm
0.000 0.297 0.703
E05.4 Thyrotoxicosis factitia
0.000 0.297 0.703
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.297 0.703
E70-E90 Metabolic disorders
0.004 0.298 0.698
E14.7 With multiple complications
0.000 0.299 0.701
E14.0 With coma
0.000 0.299 0.701
E15 Nondiabetic hypoglycaemic coma
0.000 0.300 0.700
G36 Other acute disseminated demyelination
0.698 0.302 0.000
E07.1 Dyshormogenetic goitre
0.000 0.305 0.695
E07.0 Hypersecretion of calcitonin
0.000 0.305 0.695
E10.6 With other specified complications
0.000 0.307 0.693
E03.1 Congenital hypothyroidism without goitre
0.000 0.311 0.689
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.312 0.688
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.312 0.688
E16.4 Abnormal secretion of gastrin
0.000 0.312 0.688
E16.3 Increased secretion of glucagon
0.000 0.312 0.688
G37.5 Concentric sclerosis [Balo]
0.686 0.314 0.000
G37.4 Subacute necrotising myelitis
0.686 0.314 0.000
G37.2 Central pontine myelinolysis
0.686 0.314 0.000
G37.1 Central demyelination of corpus callosum
0.686 0.314 0.000
G37.0 Diffuse sclerosis
0.686 0.314 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.324 0.676
E14.2 Withrenal complications
0.000 0.326 0.674
E14.4 With neurological complications
0.000 0.329 0.671
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.356 0.644
L40.0 Psoriasis vulgaris
0.000 0.358 0.642
E11.8 With unspecified complications
0.000 0.363 0.637
L40.8 Other psoriasis
0.000 0.363 0.637
E78.2 Mixed hyperlipidaemia
0.000 0.379 0.621
E65-E68 Obesity and other hyperalimentation
0.000 0.384 0.616
L40.1 Generalised pustular psoriasis
0.000 0.385 0.615
E78.5 Hyperlipidaemia, unspecified
0.000 0.386 0.614
L40.2 Acrodermatitis continua
0.000 0.392 0.608
E40-E46 Malnutrition
0.000 0.404 0.596
E14.5 With peripheral circulatory complications
0.000 0.412 0.588
E05.8 Other thyrotoxicosis
0.000 0.414 0.586
L40.4 Guttate psoriasis
0.000 0.419 0.581
L40.3 Pustulosis palmaris et plantaris
0.000 0.424 0.576
E13 Other specified diabetes mellitus
0.000 0.425 0.575
E06 Thyroiditis
0.000 0.433 0.567
E78.8 Other disorders of lipoprotein metabolism
0.000 0.445 0.555
E78.6 Lipoprotein deficiency
0.000 0.453 0.547
E10.2 With renal complications
0.000 0.455 0.545
E10.5 With peripheral circulatory complications
0.000 0.464 0.536
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.471 0.529
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E11.0 With coma
0.000 0.487 0.513
E78.4 Other hyperlipidaemia
0.000 0.487 0.513
G36.0 Neuromyelitis optica [Devic]
0.507 0.493 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.001 0.494 0.505
E77 Disorders of glycoprotein metabolism
0.003 0.497 0.500
E76 Disorders of glycosaminoglycan metabolism
0.003 0.497 0.500
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.003 0.497 0.500
E70 Disorders of aromatic amino-acid metabolism
0.003 0.497 0.500
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.003 0.497 0.500
G36.9 Acute disseminated demyelination, unspecified
0.500 0.499 0.000
G36.8 Other specified acute disseminated demyelination
0.500 0.499 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.500 0.499 0.000
E79 Disorders of purine and pyrimidine metabolism
0.003 0.499 0.498
E20-E35 Disorders of other endocrine glands
0.000 0.502 0.498
E11.5 With peripheral circulatory complications
0.000 0.503 0.497
E83 Disorders of mineral metabolism
0.470 0.505 0.026
E78.1 Pure hyperglyceridaemia
0.000 0.506 0.494
E72 Other disorders of amino-acid metabolism
0.003 0.517 0.480
J45.9 Asthma, unspecified
0.000 0.520 0.480
E88 Other metabolic disorders
0.002 0.523 0.475
E29 Testicular dysfunction
0.000 0.532 0.468
E14.6 With other specified complications
0.001 0.537 0.462
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.003 0.542 0.455
E74 Other disorders of carbohydrate metabolism
0.003 0.552 0.445
E29.1 Testicular hypofunction
0.000 0.553 0.447
E78.3 Hyperchylomicronaemia
0.000 0.556 0.444
E67 Other hyperalimentation
0.000 0.558 0.442
E68 Sequelae of hyperalimentation
0.000 0.558 0.442
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.572 0.428
E45 Retarded development following protein-energy malnutrition
0.000 0.572 0.428
E43 Unspecified severe protein-energy malnutrition
0.000 0.572 0.428
E42 Marasmic kwashiorkor
0.000 0.572 0.428
E41 Nutritional marasmus
0.000 0.572 0.428
E40 Kwashiorkor
0.000 0.572 0.428
I10-I15 Hypertensive diseases
0.000 0.575 0.425
E84 Cystic fibrosis
0.003 0.576 0.420
E22 Hyperfunction of pituitary gland
0.000 0.586 0.414
E13.8 With unspecified complications
0.000 0.587 0.412
E13.7 With multiple complications
0.000 0.587 0.412
E13.6 With other specified complications
0.000 0.587 0.412
E13.5 With peripheral circulatory complications
0.000 0.587 0.412
E13.4 With neurological complications
0.000 0.587 0.412
E13.2 With renal complications
0.000 0.587 0.412
E13.1 With ketoacidosis
0.000 0.587 0.412
E13.0 With coma
0.000 0.587 0.412
E26 Hyperaldosteronism
0.000 0.589 0.411
E65 Localised adiposity
0.000 0.591 0.409
E06.5 Other chronic thyroiditis
0.000 0.591 0.408
E06.4 Drug-induced thyroiditis
0.000 0.594 0.406
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.594 0.406
E06.1 Subacute thyroiditis
0.000 0.594 0.406
E06.0 Acute thyroiditis
0.000 0.594 0.406
E88.2 Lipomatosis, not elsewhere classified
0.001 0.595 0.404
E13.3 With ophthalmic complications
0.000 0.596 0.404
E73 Lactose intolerance
0.003 0.597 0.400
E83.3 Disorders of phosphorus metabolism
0.387 0.606 0.008
E83.9 Disorder of mineral metabolism, unspecified
0.371 0.613 0.016
E66 Obesity
0.000 0.615 0.384
E06.9 Thyroiditis, unspecified
0.000 0.621 0.378
E80 Disorders of porphyrin and bilirubin metabolism
0.003 0.628 0.369
E88.8 Other specified metabolic disorders
0.001 0.634 0.365
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.638 0.362
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.002 0.639 0.359
E70.8 Other disorders of aromatic amino-acid metabolism
0.002 0.639 0.359
E70.3 Albinism
0.002 0.639 0.359
E70.2 Disorders of tyrosine metabolism
0.002 0.639 0.359
E70.1 Other hyperphenylalaninaemias
0.002 0.639 0.359
E70.0 Classical phenylketonuria
0.002 0.639 0.359
E71.3 Disorders of fatty-acid metabolism
0.002 0.639 0.359
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.002 0.639 0.359
E71.1 Other disorders of branched-chain amino-acid metabolism
0.002 0.639 0.359
E71.0 Maple-syrup-urine disease
0.002 0.639 0.359
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.002 0.639 0.359
E76.8 Other disorders of glucosaminoglycan metabolism
0.002 0.639 0.359
E76.3 Mucopolysaccharidosis, unspecified
0.002 0.639 0.359
E76.2 Other mucopolysaccharidoses
0.002 0.639 0.359
E76.1 Mucopolysaccharidosis, type II
0.002 0.639 0.359
E76.0 Mucopolysaccharidosis, type I
0.002 0.639 0.359
E77.9 Disorder of glycoprotein metabolism, unspecified
0.002 0.639 0.359
E77.8 Other disorders of glycoprotein metabolism
0.002 0.639 0.359
E77.1 Defects in glycoprotein degradation
0.002 0.639 0.359
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.002 0.639 0.359
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.002 0.641 0.357
E79.8 Other disorders of purine and pyrimidine metabolism
0.002 0.641 0.357
E79.1 Lesch-Nyhan syndrome
0.002 0.641 0.357
E28 Ovarian dysfunction
0.000 0.641 0.359
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.643 0.357
E32 Diseases of thymus
0.000 0.643 0.357
E31 Polyglandular dysfunction
0.000 0.643 0.357
E30 Disorders of puberty, not elsewhere classified
0.000 0.643 0.357
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.002 0.644 0.354
E83.8 Other disorders of mineral metabolism
0.337 0.645 0.019
E83.2 Disorders of zinc metabolism
0.337 0.645 0.019
E83.0 Disorders of copper metabolism
0.337 0.645 0.019
E88.3 Tumour lysis syndrome
0.001 0.647 0.352
E26.0 Primary hyperaldosteronism
0.000 0.652 0.348
E72.9 Disorder of amino-acid metabolism, unspecified
0.002 0.653 0.344
E72.8 Other specified disorders of amino-acid metabolism
0.002 0.653 0.344
E72.5 Disorders of glycine metabolism
0.002 0.653 0.344
E72.4 Disorders of ornithine metabolism
0.002 0.653 0.344
E72.3 Disorders of lysine and hydroxylysine metabolism
0.002 0.653 0.344
E72.2 Disorders of urea cycle metabolism
0.002 0.653 0.344
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.002 0.653 0.344
E23 Hypofunction and other disorders of pituitary gland
0.000 0.658 0.342
E29.9 Testicular dysfunction, unspecified
0.000 0.664 0.336
E29.8 Other testicular dysfunction
0.000 0.664 0.336
E29.0 Testicular hyperfunction
0.000 0.664 0.336
E75.6 Lipid storage disorder, unspecified
0.002 0.671 0.326
E75.4 Neuronal ceroid lipofuscinosis
0.002 0.671 0.326
E75.3 Sphingolipidosis, unspecified
0.002 0.671 0.326
E75.1 Other gangliosidosis
0.002 0.671 0.326
E75.0 GM2 gangliosidosis
0.002 0.671 0.326
E72.0 Disorders of amino-acid transport
0.002 0.673 0.324
I11 Hypertensive heart disease
0.000 0.676 0.324
E74.3 Other disorders of intestinal carbohydrate absorption
0.002 0.677 0.321
E74.9 Disorder of carbohydrate metabolism, unspecified
0.002 0.679 0.319
E74.8 Other specified disorders of carbohydrate metabolism
0.002 0.679 0.319
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.002 0.679 0.319
E74.2 Disorders of galactose metabolism
0.002 0.679 0.319
E74.1 Disorders of fructose metabolism
0.002 0.679 0.319
E25 Adrenogenital disorders
0.000 0.679 0.321
E66.9 Obesity, unspecified
0.000 0.680 0.320
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.680 0.318
E66.0 Obesity due to excess calories
0.000 0.682 0.318
E67.8 Other specified hyperalimentation
0.000 0.683 0.317
E67.3 Hypervitaminosis D
0.000 0.683 0.317
E67.2 Megavitamin-B6 syndrome
0.000 0.683 0.317
E67.1 Hypercarotenaemia
0.000 0.683 0.317
E67.0 Hypervitaminosis A
0.000 0.683 0.317
I12 Hypertensive renal disease
0.000 0.686 0.314
E20 Hypoparathyroidism
0.000 0.689 0.311
E75.2 Other sphingolipidosis
0.002 0.690 0.308
E46 Unspecified protein-energy malnutrition
0.000 0.693 0.307
E44.1 Mild protein-energy malnutrition
0.000 0.693 0.307
E44.0 Moderate protein-energy malnutrition
0.000 0.693 0.307
E75.5 Other lipid storage disorders
0.002 0.694 0.303
I13 Hypertensive heart and renal disease
0.000 0.695 0.305
E84.8 Cystic fibrosis with other manifestations
0.003 0.696 0.301
E84.1 Cystic fibrosis with intestinal manifestations
0.003 0.696 0.301
E22.1 Hyperprolactinaemia
0.000 0.698 0.302
E06.3 Autoimmune thyroiditis
0.000 0.702 0.298
E23.7 Disorder of pituitary gland, unspecified
0.000 0.703 0.297
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.703 0.297
E22.8 Other hyperfunction of pituitary gland
0.000 0.703 0.297
E88.9 Metabolic disorder, unspecified
0.002 0.705 0.293
E26.9 Hyperaldosteronism, unspecified
0.000 0.705 0.295
E26.8 Other hyperaldosteronism
0.000 0.705 0.295
E26.1 Secondary hyperaldosteronism
0.000 0.705 0.295
E24 Cushing's syndrome
0.000 0.706 0.293
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.001 0.710 0.288
E73.8 Other lactose intolerance
0.002 0.711 0.287
E73.1 Secondary lactase deficiency
0.002 0.711 0.287
E73.0 Congenital lactase deficiency
0.002 0.711 0.287
E80.2 Other porphyria
0.002 0.711 0.287
E28.3 Primary ovarian failure
0.000 0.713 0.287
E13.9 Without complications
0.000 0.714 0.286
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.714 0.286
E80.1 Porphyria cutanea tarda
0.002 0.715 0.283
E84.9 Cystic fibrosis, unspecified
0.003 0.721 0.276
E83.4 Disorders of magnesium metabolism
0.269 0.724 0.007
E66.1 Drug-induced obesity
0.000 0.724 0.276
I15 Secondary hypertension
0.000 0.726 0.274
I12.9 Hypertensive renal disease without renal failure
0.000 0.727 0.273
E22.0 Acromegaly and pituitary gigantism
0.000 0.730 0.270
E80.6 Other disorders of bilirubin metabolism
0.002 0.733 0.266
E86 Volume depletion
0.000 0.733 0.267
E80.5 Crigler-Najjar syndrome
0.002 0.733 0.265
E80.3 Defects of catalase and peroxydase
0.002 0.733 0.265
E80.0 Hereditary erythropoietic porphyria
0.002 0.733 0.265
E74.0 Glycogen storage disease
0.003 0.737 0.260
E50-E64 Other nutritional deficiencies
0.000 0.740 0.260
E84.0 Cystic fibrosis with pulmonary manifestations
0.003 0.741 0.256
E28.9 Ovarian dysfunction, unspecified
0.000 0.742 0.257
E28.8 Other ovarian dysfunction
0.000 0.742 0.257
E28.1 Androgen excess
0.000 0.742 0.257
E28.0 Oestrogen excess
0.000 0.742 0.257
E30.9 Disorder of puberty, unspecified
0.000 0.744 0.256
E30.8 Other disorders of puberty
0.000 0.744 0.256
E30.1 Precocious puberty
0.000 0.744 0.256
E30.0 Delayed puberty
0.000 0.744 0.256
E31.9 Polyglandular dysfunction, unspecified
0.000 0.744 0.256
E31.8 Other polyglandular dysfunction
0.000 0.744 0.256
E31.1 Polyglandular hyperfunction
0.000 0.744 0.256
E31.0 Autoimmune polyglandular failure
0.000 0.744 0.256
E32.9 Disease of thymus, unspecified
0.000 0.744 0.256
E32.8 Other diseases of thymus
0.000 0.744 0.256
E32.1 Abscess of thymus
0.000 0.744 0.256
E32.0 Persistent hyperplasia of thymus
0.000 0.744 0.256
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.744 0.256
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.744 0.256
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.744 0.256
L40-L45 Papulosquamous disorders
0.000 0.748 0.252
E24.2 Drug-induced Cushing's syndrome
0.000 0.750 0.250
K60.2 Anal fissure, unspecified
0.000 0.750 0.250
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.754 0.246
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.755 0.245
E23.1 Drug-induced hypopituitarism
0.000 0.755 0.245
E85 Amyloidosis
0.004 0.755 0.241
E23.6 Other disorders of pituitary gland
0.000 0.755 0.245
E80.7 Disorder of bilirubin metabolism, unspecified
0.002 0.762 0.236
E25.9 Adrenogenital disorder, unspecified
0.000 0.770 0.230
E25.8 Other adrenogenital disorders
0.000 0.770 0.230
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.001 0.776 0.223
E20.8 Other hypoparathyroidism
0.000 0.777 0.223
E20.1 Pseudohypoparathyroidism
0.000 0.777 0.223
E20.0 Idiopathic hypoparathyroidism
0.000 0.777 0.223
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.781 0.219
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.781 0.219
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.781 0.219
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.781 0.219
E28.2 Polycystic ovarian syndrome
0.000 0.782 0.218
E34 Other endocrine disorders
0.000 0.782 0.217
I15.9 Seconday hypertension, unspecified
0.000 0.783 0.217
K90 Intestinal malabsorption
0.000 0.789 0.211
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.789 0.210
E24.3 Ectopic ACTH syndrome
0.000 0.789 0.210
E24.1 Nelson's syndrome
0.000 0.789 0.210
E23.2 Diabetes insipidus
0.000 0.792 0.208
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.001 0.792 0.207
E89.8 Other postprocedural endocrine and metabolic disorders
0.001 0.792 0.207
E89.5 Postprocedural testicular hypofunction
0.001 0.792 0.207
E89.1 Postprocedural hypoinsulinaemia
0.001 0.792 0.207
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.001 0.795 0.204
I15.1 Hypertension secondary to other renal disorders
0.000 0.795 0.205
E24.8 Other Cushing's syndrome
0.000 0.802 0.198
E89.3 Postprocedural hypopituitarism
0.001 0.802 0.197
I15.2 Hypertension secondary to endocrine disorders
0.000 0.803 0.197
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.806 0.194
E51 Thiamine deficiency
0.000 0.808 0.192
E73.9 Lactose intolerance, unspecified
0.003 0.811 0.186
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.813 0.186
E50 Vitamin A deficiency
0.000 0.813 0.186
E60 Dietary zinc deficiency
0.000 0.813 0.186
E59 Dietary selenium deficiency
0.000 0.813 0.186
E54 Ascorbic acid deficiency
0.000 0.813 0.186
E52 Niacin deficiency [pellagra]
0.000 0.813 0.186
E24.0 Pituitary-dependent Cushing's disease
0.000 0.815 0.184
E89.2 Postprocedural hypoparathyroidism
0.001 0.815 0.184
E56 Other vitamin deficiencies
0.000 0.818 0.181
E58 Dietary calcium deficiency
0.000 0.819 0.181
L44 Other papulosquamous disorders
0.000 0.819 0.181
L41 Parapsoriasis
0.000 0.819 0.181
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.819 0.181
E63 Other nutritional deficiencies
0.000 0.822 0.178
E20.9 Hypoparathyroidism, unspecified
0.000 0.823 0.177
E85.2 Heredofamilial amyloidosis, unspecified
0.003 0.824 0.173
E85.1 Neuropathic heredofamilial amyloidosis
0.003 0.824 0.173
E85.0 Nonneuropathic heredofamilial amyloidosis
0.003 0.824 0.173
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.825 0.175
I15.8 Other secondary hypertension
0.000 0.828 0.172
E23.0 Hypopituitarism
0.000 0.830 0.170
E61 Deficiency of other nutrient elements
0.000 0.836 0.164
E89.0 Postprocedural hypothyroidism
0.000 0.836 0.164
L42 Pityriasis rosea
0.000 0.836 0.164
E85.8 Other amyloidosis
0.003 0.836 0.160
E89.4 Postprocedural ovarian failure
0.001 0.840 0.159
E34.5 Androgen resistance syndrome
0.000 0.844 0.156
E34.4 Constitutional tall stature
0.000 0.844 0.156
E34.3 Short stature, not elsewhere classified
0.000 0.844 0.156
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.844 0.156
E34.1 Other hypersecretion of intestinal hormones
0.000 0.844 0.156
L43 Lichen planus
0.000 0.846 0.154
I15.0 Renovascular hypertension
0.000 0.847 0.153
I11.0 Hypertensive heart disease with (congestive) heart failure
0.001 0.848 0.151
K90.3 Pancreatic steatorrhoea
0.000 0.849 0.151
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.849 0.151
K90.1 Tropical sprue
0.000 0.849 0.151
E83.5 Disorders of calcium metabolism
0.146 0.851 0.003
E85.3 Secondary systemic amyloidosis
0.003 0.855 0.142
E51.2 Wernicke's encephalopathy
0.000 0.857 0.143
I12.0 Hypertensive renal disease with renal failure
0.000 0.858 0.142
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.859 0.141
E85.9 Amyloidosis, unspecified
0.003 0.860 0.137
E51.9 Thiamine deficiency, unspecified
0.000 0.862 0.138
E51.8 Other manifestations of thiamine deficiency
0.000 0.862 0.138
E51.1 Beriberi
0.000 0.862 0.138
E50.9 Vitamin A deficiency, unspecified
0.000 0.866 0.134
E50.8 Other manifestations of vitamin A deficiency
0.000 0.866 0.134
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.866 0.134
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.866 0.134
E50.5 Vitamin A deficiency with night blindness
0.000 0.866 0.134
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.866 0.134
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.866 0.134
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.866 0.134
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.866 0.134
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.866 0.134
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.866 0.134
E64.8 Sequelae of other nutritional deficiencies
0.000 0.866 0.134
E64.3 Sequelae of rickets
0.000 0.866 0.134
E64.2 Sequelae of vitamin C deficiency
0.000 0.866 0.134
E64.1 Sequelae of vitamin A deficiency
0.000 0.866 0.134
E64.0 Sequelae of protein-energy malnutrition
0.000 0.866 0.134
E34.8 Other specified endocrine disorders
0.000 0.866 0.134
K90.9 Intestinal malabsorption, unspecified
0.000 0.866 0.134
E56.9 Vitamin deficiency, unspecified
0.000 0.869 0.130
E56.8 Deficiency of other vitamins
0.000 0.869 0.130
E56.0 Deficiency of vitamin E
0.000 0.869 0.130
L41.9 Parapsoriasis, unspecified
0.000 0.870 0.130
L41.8 Other parapsoriasis
0.000 0.870 0.130
L41.5 Retiform parapsoriasis
0.000 0.870 0.130
L41.4 Large plaque parapsoriasis
0.000 0.870 0.130
L41.3 Small plaque parapsoriasis
0.000 0.870 0.130
L41.2 Lymphomatoid papulosis
0.000 0.870 0.130
L41.1 Pityriasis lichenoides chronica
0.000 0.870 0.130
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.870 0.130
L44.9 Papulosquamous disorder, unspecified
0.000 0.870 0.130
L44.8 Other specified papulosquamous disorders
0.000 0.870 0.130
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.870 0.130
L44.3 Lichen ruber moniliformis
0.000 0.870 0.130
L44.2 Lichen striatus
0.000 0.870 0.130
L44.1 Lichen nitidus
0.000 0.870 0.130
L44.0 Pityriasis rubra pilaris
0.000 0.870 0.130
E27 Other disorders of adrenal gland
0.000 0.871 0.129
E63.8 Other specified nutritional deficiencies
0.000 0.872 0.128
E63.1 Imbalance of constituents of food intake
0.000 0.872 0.128
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.872 0.128
E34.9 Endocrine disorder, unspecified
0.000 0.874 0.126
E21.4 Other specified disorders of parathyroid gland
0.000 0.874 0.126
E56.1 Deficiency of vitamin K
0.000 0.874 0.125
K90.8 Other intestinal malabsorption
0.000 0.875 0.125
E55 Vitamin D deficiency
0.000 0.876 0.124
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.877 0.123
E85.4 Organ-limited amyloidosis
0.003 0.879 0.118
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.880 0.120
E63.9 Nutritional deficiency, unspecified
0.000 0.880 0.119
E34.0 Carcinoid syndrome
0.000 0.881 0.118
E61.9 Deficiency of nutrient element, unspecified
0.000 0.882 0.118
E61.8 Deficiency of other specified nutrient elements
0.000 0.882 0.118
E61.7 Deficiency of multiple nutrient elements
0.000 0.882 0.118
E61.6 Vanadium deficiency
0.000 0.882 0.118
E61.5 Molybdenum deficiency
0.000 0.882 0.118
E61.4 Chromium deficiency
0.000 0.882 0.118
E61.3 Manganese deficiency
0.000 0.882 0.118
E61.0 Copper deficiency
0.000 0.882 0.118
L43.8 Other lichen planus
0.000 0.882 0.117
R07.4 Chest pain, unspecified
0.000 0.884 0.116
E21.2 Other hyperparathyroidism
0.000 0.887 0.113
L43.3 Subacute (active) lichen planus
0.000 0.890 0.110
L43.2 Lichenoid drug reaction
0.000 0.890 0.110
L43.1 Bullous lichen planus
0.000 0.890 0.110
L43.0 Hypertrophic lichen planus
0.000 0.890 0.110
E24.9 Cushing's syndrome, unspecified
0.001 0.890 0.109
E61.2 Magnesium deficiency
0.000 0.892 0.108
E61.1 Iron deficiency
0.000 0.892 0.108
E04 Other non-toxic goitre
0.000 0.896 0.104
E27.9 Disorder of adrenal gland, unspecified
0.000 0.905 0.095
R07.0 Pain in throat
0.095 0.905 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.907 0.093
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.907 0.093
E27.0 Other adrenocortical overactivity
0.000 0.907 0.093
K60 Fissure and fistula of anal and rectal regions
0.000 0.909 0.091
E55.0 Rickets, active
0.000 0.911 0.089
E11.4 With neurological complications
0.002 0.917 0.081
E80.4 Gilbert's syndrome
0.002 0.917 0.081
J45 Asthma
0.000 0.921 0.079
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.922 0.078
K60.5 Anorectal fistula
0.000 0.922 0.078
E04.0 Non-toxic diffuse goitre
0.000 0.923 0.077
E04.8 Other specified non-toxic goitre
0.000 0.925 0.075
E53 Deficiency of other B group vitamins
0.001 0.927 0.073
E21.3 Hyperparathyroidism, unspecified
0.000 0.928 0.072
M79.65 Pain in limb (Pelvic region and thigh)
0.000 0.931 0.069
L43.9 Lichen planus, unspecified
0.000 0.931 0.069
E27.8 Other specified disorders of adrenal gland
0.000 0.933 0.067
K60.0 Acute anal fissure
0.000 0.935 0.065
E27.2 Addisonian crisis
0.000 0.935 0.065
K60.4 Rectal fistula
0.000 0.937 0.063
E27.1 Primary adrenocortical insufficiency
0.000 0.939 0.061
E21.0 Primary hyperparathyroidism
0.000 0.942 0.058
K60.1 Chronic anal fissure
0.000 0.945 0.055
E53.1 Pyridoxine deficiency
0.001 0.947 0.052
E53.0 Riboflavin deficiency
0.001 0.947 0.052
J45.1 Nonallergic asthma
0.000 0.947 0.053
N83.1 Corpus luteum cyst
0.000 0.948 0.052
K60.3 Anal fistula
0.000 0.950 0.050
M24.16 Other articular cartilage disorders (Lower leg)
0.000 0.950 0.050
M79.6 Pain in limb
0.000 0.951 0.049
M79.63 Pain in limb (Forearm)
0.000 0.952 0.048

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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