TreeWAS – Variant ID: rs10799824

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E04.2 Non-toxic multinodular goitre	1.000	0.000	0.000
E04 Other non-toxic goitre	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.999	0.001	0.000
E04.9 Non-toxic goitre, unspecified	0.969	0.031	0.000
E07 Other disorders of thyroid	0.923	0.077	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.911	0.089	0.000
E04.0 Non-toxic diffuse goitre	0.901	0.099	0.000
E06 Thyroiditis	0.851	0.149	0.000
E07.9 Disorder of thyroid, unspecified	0.837	0.163	0.000
E05.9 Thyrotoxicosis, unspecified	0.835	0.165	0.000
E05.8 Other thyrotoxicosis	0.780	0.220	0.000
E07.8 Other specified disorders of thyroid	0.757	0.243	0.000
M16.0 Primary coxarthrosis, bilateral	0.735	0.265	0.000
E04.8 Other specified non-toxic goitre	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
M16 Coxarthrosis [arthrosis of hip]	0.714	0.286	0.000
E06.5 Other chronic thyroiditis	0.713	0.287	0.000
M16.1 Other primary coxarthrosis	0.707	0.293	0.000
E06.3 Autoimmune thyroiditis	0.671	0.329	0.000
E07.1 Dyshormogenetic goitre	0.662	0.338	0.000
E07.0 Hypersecretion of calcitonin	0.662	0.338	0.000
E06.4 Drug-induced thyroiditis	0.610	0.389	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.610	0.389	0.000
E06.1 Subacute thyroiditis	0.610	0.389	0.000
E06.0 Acute thyroiditis	0.610	0.389	0.000
E06.9 Thyroiditis, unspecified	0.604	0.396	0.000
M16.6 Other secondary coxarthrosis, bilateral	0.557	0.443	0.000
M15-M19 Arthrosis	0.555	0.445	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.541	0.459	0.000
H65-H75 Diseases of middle ear and mastoid	0.538	0.462	0.000
M16.5 Other posttraumatic coxarthrosis	0.537	0.463	0.000
M80-M85 Disorders of bone density and structure	0.532	0.468	0.000
M16.7 Other secondary coxarthrosis	0.526	0.474	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.523	0.477	0.000
H66 Suppurative and unspecified otitis media	0.522	0.478	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.521	0.479	0.000
M86-M90 Other osteopathies	0.521	0.479	0.000
H73 Other disorders of tympanic membrane	0.520	0.480	0.000
Chapter VIII Diseases of the ear and mastoid process	0.519	0.481	0.000
Chapter VII Diseases of the eye and adnexa	0.518	0.482	0.000
H25-H28 Disorders of lens	0.516	0.484	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.514	0.486	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.514	0.486	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.514	0.486	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.514	0.486	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.514	0.486	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.514	0.486	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.514	0.486	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.514	0.486	0.000
# Top node	0.514	0.486	0.000
M16.4 Posttraumatic coxarthrosis, bilateral	0.512	0.488	0.000
H73.8 Other specified disorders of tympanic membrane	0.509	0.491	0.000
H26 Other cataract	0.505	0.495	0.000
H26.9 Cataract, unspecified	0.503	0.497	0.000
H66.9 Otitis media, unspecified	0.502	0.498	0.000
Q80-Q89 Other congenital malformations	0.502	0.498	0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.498	0.502	0.000
M85 Other disorders of bone density and structure	0.498	0.502	0.000
H10-H13 Disorders of conjunctiva	0.495	0.505	0.000
M65-M68 Disorders of synovium and tendon	0.493	0.507	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.492	0.508	0.000
M87 Osteonecrosis	0.491	0.509	0.000
Q60-Q64 Congenital malformations of the urinary system	0.483	0.517	0.000
M84 Disorders of continuity of bone	0.482	0.518	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.476	0.524	0.000
Chapter XX External causes of morbidity and mortality	0.476	0.524	0.000
H11 Other disorders of conjunctiva	0.472	0.528	0.000
M87.9 Osteonecrosis, unspecified	0.467	0.533	0.000
H74 Other disorders of middle ear and mastoid	0.466	0.534	0.000
H71 Cholesteatoma of middle ear	0.465	0.535	0.000
M80 Osteoporosis with pathological fracture	0.460	0.540	0.000
H27 Other disorders of lens	0.459	0.541	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.457	0.543	0.000
M88 Paget's disease of bone [osteitis deformans]	0.456	0.544	0.000
H18 Other disorders of cornea	0.456	0.544	0.000
M67 Other disorders of synovium and tendon	0.455	0.545	0.000
W00-W19 Falls	0.455	0.545	0.000
H49 Paralytic strabismus	0.454	0.546	0.000
Q00-Q07 Congenital malformations of the nervous system	0.452	0.548	0.000
Q82 Other congenital malformations of skin	0.451	0.549	0.000
M00-M03 Infectious arthropathies	0.450	0.550	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.445	0.555	0.000
M85.6 Other cyst of bone	0.445	0.555	0.000
M85.0 Fibrous dysplasia (monostotic)	0.444	0.556	0.000
E70-E90 Metabolic disorders	0.444	0.556	0.000
M60-M63 Disorders of muscles	0.440	0.560	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.438	0.562	0.000
H18.4 Corneal degeneration	0.438	0.562	0.000
M67.8 Other specified disorders of synovium and tendon	0.438	0.562	0.000
H15 Disorders of sclera	0.437	0.563	0.000
H30-H36 Disorders of choroid and retina	0.436	0.564	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.435	0.565	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.435	0.565	0.000
M18 Arthrosis of first carpometacarpal joint	0.434	0.566	0.000
Q85 Phakomatoses, not elsewhere classified	0.434	0.566	0.000
H72 Perforation of tympanic membrane	0.432	0.568	0.000
Q61 Cystic kidney disease	0.431	0.569	0.000
H11.8 Other specified disorders of conjunctiva	0.430	0.570	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.429	0.571	0.000
H70 Mastoiditis and related conditions	0.429	0.571	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.424	0.576	0.000
E89.0 Postprocedural hypothyroidism	0.423	0.577	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.423	0.577	0.000
Q50-Q56 Congenital malformations of genital organs	0.421	0.579	0.000
H52 Disorders of refraction and accommodation	0.418	0.582	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.414	0.586	0.000
H49.1 Fourth [trochlear] nerve palsy	0.413	0.587	0.000
Q82.8 Other specified congenital malformations of skin	0.413	0.587	0.000
W50-W64 Exposure to animate mechanical forces	0.411	0.589	0.000
V01-V09 Pedestrian injured in transport accident	0.411	0.589	0.000
M88.9 Paget's disease of bone, unspecified	0.410	0.590	0.000
H25 Senile cataract	0.409	0.591	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.408	0.592	0.000
H11.1 Conjunctival degenerations and deposits	0.407	0.593	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.406	0.594	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.406	0.594	0.000
Q61.2 Polycystic kidney, adult type	0.405	0.595	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.405	0.595	0.000
Q89 Other congenital malformations, not elsewhere classified	0.404	0.596	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.403	0.597	0.000
H27.0 Aphakia	0.403	0.597	0.000
H66.3 Other chronic suppurative otitis media	0.402	0.598	0.000
M66 Spontaneous rupture of synovium and tendon	0.402	0.598	0.000
H31 Other disorders of choroid	0.401	0.599	0.000
H90-H95 Other disorders of ear	0.400	0.600	0.000
H16 Keratitis	0.400	0.600	0.000
W75-W84 Other accidental threats to breathing	0.397	0.603	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.397	0.603	0.000
H10 Conjunctivitis	0.397	0.603	0.000
H49.4 Progressive external ophthalmoplegia	0.396	0.604	0.000
H72.0 Central perforation of tympanic membrane	0.395	0.605	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.394	0.606	0.000
H26.8 Other specified cataract	0.393	0.607	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.392	0.608	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.391	0.609	0.000
H66.0 Acute suppurative otitis media	0.389	0.611	0.000
M81 Osteoporosis without pathological fracture	0.388	0.612	0.000
H34 Retinal vascular occlusions	0.388	0.612	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.387	0.613	0.000
H18.5 Hereditary corneal dystrophies	0.387	0.613	0.000
H27.8 Other specified disorders of lens	0.386	0.614	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.386	0.614	0.000
H68 Eustachian salpingitis and obstruction	0.386	0.614	0.000
H67 Otitis media in diseases classified elsewhere	0.386	0.614	0.000
E74 Other disorders of carbohydrate metabolism	0.386	0.614	0.000
H11.0 Pterygium	0.385	0.615	0.000
H26.0 Infantile, juvenile and presenile cataract	0.385	0.615	0.000
E89.2 Postprocedural hypoparathyroidism	0.385	0.615	0.000
Q05 Spina bifida	0.383	0.617	0.000
M15 Polyarthrosis	0.383	0.617	0.000
M83 Adult osteomalacia	0.382	0.618	0.000
M89 Other disorders of bone	0.382	0.618	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.381	0.619	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.381	0.619	0.000
M85.9 Disorder of bone density and structure, unspecified	0.381	0.619	0.000
H15.0 Scleritis	0.381	0.619	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.381	0.619	0.000
M87.2 Osteonecrosis due to previous trauma	0.379	0.621	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.378	0.622	0.000
E03 Other hypothyroidism	0.360	0.623	0.017
X50-X57 Overexertion, travel and privation	0.376	0.623	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.376	0.624	0.000
V70-V79 Bus occupant injured in transport accident	0.376	0.624	0.000
W08 Fall involving other furniture	0.376	0.624	0.000
W19 Unspecified fall	0.376	0.624	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.375	0.625	0.000
E88 Other metabolic disorders	0.375	0.625	0.000
Q35-Q37 Cleft lip and cleft palate	0.375	0.625	0.000
H66.4 Suppurative otitis media, unspecified	0.374	0.625	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.374	0.625	0.000
W15 Fall from cliff	0.373	0.626	0.000
W03 Other fall on same level due to collision with, or pushing by, another person	0.373	0.627	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.373	0.627	0.000
H73.1 Chronic myringitis	0.373	0.627	0.000
H73.0 Acute myringitis	0.373	0.627	0.000
Q63 Other congenital malformations of kidney	0.372	0.628	0.000
Q76 Congenital malformations of spine and bony thorax	0.372	0.628	0.000
H18.0 Corneal pigmentations and deposits	0.371	0.629	0.000
W00 Fall on same level involving ice and snow	0.370	0.630	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.370	0.630	0.000
X00-X09 Exposure to smoke, fire and flames	0.370	0.630	0.000
M67.4 Ganglion	0.370	0.630	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.368	0.632	0.000
M00 Pyogenic arthritis	0.368	0.632	0.000
Y79 Orthopaedic devices associated with adverse incidents	0.367	0.633	0.000
M90 Osteopathies in diseases classified elsewhere	0.367	0.633	0.000
H49.8 Other paralytic strabismus	0.367	0.633	0.000
Q74 Other congenital malformations of limb(s)	0.366	0.634	0.000
Q64 Other congenital malformations of urinary system	0.366	0.634	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.365	0.635	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.365	0.635	0.000
H31.8 Other specified disorders of choroid	0.364	0.636	0.000
W11 Fall on and from ladder	0.364	0.636	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.363	0.637	0.000
H26.3 Drug-induced cataract	0.362	0.637	0.000
Q51 Congenital malformations of uterus and cervix	0.362	0.638	0.000
X59 Exposure to unspecified factor	0.362	0.638	0.000
H72.1 Attic perforation of tympanic membrane	0.361	0.639	0.000
H52.1 Myopia	0.361	0.639	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.360	0.640	0.000
Q84 Other congenital malformations of integument	0.360	0.640	0.000
Q81 Epidermolysis bullosa	0.360	0.640	0.000
Q80 Congenital ichthyosis	0.360	0.640	0.000
M62 Other disorders of muscle	0.360	0.640	0.000
H49.9 Paralytic strabismus, unspecified	0.359	0.641	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.359	0.641	0.000
V95-V97 Air and space transport accidents	0.359	0.641	0.000
M85.5 Aneurysmal bone cyst	0.357	0.643	0.000
M85.4 Solitary bone cyst	0.357	0.643	0.000
M85.3 Osteitis condensans	0.357	0.643	0.000
M85.2 Hyperostosis of skull	0.357	0.643	0.000
M85.1 Skeletal fluorosis	0.357	0.643	0.000
Y00-Y09 Assault	0.357	0.643	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.356	0.644	0.000
Y77 Ophthalmic devices associated with adverse incidents	0.355	0.645	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.355	0.645	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.355	0.645	0.000
W13 Fall from, out of or through building or structure	0.354	0.646	0.000
M86 Osteomyelitis	0.354	0.646	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.354	0.646	0.000
Q83 Congenital malformations of breast	0.354	0.646	0.000
M87.3 Other secondary osteonecrosis	0.352	0.648	0.000
M87.1 Osteonecrosis due to drugs	0.352	0.648	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.352	0.648	0.000
H11.2 Conjunctival scars	0.351	0.649	0.000
M45-M49 Spondylopathies	0.350	0.650	0.000
M02 Reactive arthropathies	0.350	0.650	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.349	0.651	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.349	0.651	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.348	0.651	0.000
H26.1 Traumatic cataract	0.348	0.652	0.000
H25.8 Other senile cataract	0.348	0.652	0.000
H25.0 Senile incipient cataract	0.347	0.653	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.346	0.653	0.000
V90-V94 Water transport accidents	0.346	0.654	0.000
M84.9 Disorder of continuity of bone, unspecified	0.346	0.654	0.000
M84.8 Other disorders of continuity of bone	0.346	0.654	0.000
M84.3 Stress fracture, not elsewhere classified	0.346	0.654	0.000
M84.2 Delayed union of fracture	0.346	0.654	0.000
M16.3 Other dysplastic coxarthrosis	0.345	0.654	0.000
H15.1 Episcleritis	0.345	0.655	0.000
H92 Otalgia and effusion of ear	0.344	0.656	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.344	0.656	0.000
H74.0 Tympanosclerosis	0.344	0.656	0.000
H74.1 Adhesive middle ear disease	0.343	0.657	0.000
W19.3 Sports and athletics area	0.342	0.658	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.342	0.658	0.000
E89.3 Postprocedural hypopituitarism	0.342	0.658	0.000
M87.8 Other osteonecrosis	0.342	0.658	0.000
H51 Other disorders of binocular movement	0.342	0.658	0.000
Y35-Y36 Legal intervention and operations of war	0.342	0.658	0.000
X85-X99 Assault	0.342	0.658	0.000
X30-X39 Exposure to forces of nature	0.342	0.658	0.000
W65-W74 Accidental drowning and submersion	0.342	0.658	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.342	0.658	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.342	0.658	0.000
Q07 Other congenital malformations of nervous system	0.341	0.659	0.000
Q28 Other congenital malformations of circulatory system	0.340	0.660	0.000
E85 Amyloidosis	0.340	0.660	0.000
H11.3 Conjunctival haemorrhage	0.340	0.660	0.000
Q03 Congenital hydrocephalus	0.340	0.660	0.000
Y10-Y34 Event of undetermined intent	0.339	0.661	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.339	0.661	0.000
W14 Fall from tree	0.338	0.662	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.338	0.662	0.000
V02 Pedestrian injured in collision with two- or three-wheeled motor vehicle	0.338	0.662	0.000
M66.0 Rupture of popliteal cyst	0.337	0.663	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.337	0.663	0.000
Q25 Congenital malformations of great arteries	0.336	0.664	0.000
W78 Inhalation of gastric contents	0.336	0.664	0.000
V20-V29 Motorcycle rider injured in transport accident	0.336	0.664	0.000
M82 Osteoporosis in diseases classified elsewhere	0.336	0.664	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.336	0.664	0.000
H70.1 Chronic mastoiditis	0.335	0.665	0.000
Q78 Other osteochondrodysplasias	0.335	0.665	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.335	0.665	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.335	0.665	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.335	0.665	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.335	0.665	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.335	0.665	0.000
W05 Fall involving wheelchair	0.335	0.665	0.000
E84 Cystic fibrosis	0.334	0.666	0.000
Q89.2 Congenital malformations of other endocrine glands	0.334	0.666	0.000
H34.8 Other retinal vascular occlusions	0.334	0.666	0.000
Q05.9 Spina bifida, unspecified	0.334	0.666	0.000
H65 Nonsuppurative otitis media	0.333	0.667	0.000
W55 Bitten or struck by other mammals	0.333	0.667	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.332	0.668	0.000
Y73 Gastro-enterology and urology devices associated with adverse incidents	0.331	0.669	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.330	0.669	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.330	0.670	0.000
V80-V89 Other land transport accidents	0.330	0.670	0.000
H52.2 Astigmatism	0.330	0.670	0.000
M80.8 Other osteoporosis with pathological fracture	0.330	0.670	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.330	0.670	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.330	0.670	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.330	0.670	0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents	0.330	0.670	0.000
Q82.5 Congenital nonneoplastic naevus	0.329	0.670	0.000
H26.4 After-cataract	0.330	0.670	0.000
H27.9 Disorder of lens, unspecified	0.329	0.670	0.000
M81.4 Drug-induced osteoporosis	0.329	0.670	0.000
X10-X19 Contact with heat and hot substances	0.329	0.670	0.000
H70.9 Mastoiditis, unspecified	0.328	0.672	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.327	0.672	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.327	0.672	0.000
Q04 Other congenital malformations of brain	0.327	0.672	0.000
M88.8 Paget's disease of other bones	0.327	0.673	0.000
M88.0 Paget's disease of skull	0.327	0.673	0.000
M60 Myositis	0.327	0.673	0.000
H18.7 Other corneal deformities	0.327	0.673	0.000
H18.3 Changes in corneal membranes	0.327	0.673	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.326	0.674	0.000
H49.0 Third [oculomotor] nerve palsy	0.326	0.674	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.326	0.674	0.000
M67.3 Transient synovitis	0.326	0.674	0.000
W16 Diving or jumping into water causing injury other than drowning or submersion	0.326	0.674	0.000
W12 Fall on and from scaffolding	0.326	0.674	0.000
W09 Fall involving playground equipment	0.326	0.674	0.000
W04 Fall while being carried or supported by other persons	0.326	0.674	0.000
H49.3 Total (external) ophthalmoplegia	0.326	0.674	0.000
M16.9 Coxarthrosis, unspecified	0.326	0.674	0.000
M81.2 Osteoporosis of disuse	0.325	0.675	0.000
H20 Iridocyclitis	0.325	0.675	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.325	0.675	0.000
W19.6 Industrial and construction area	0.325	0.675	0.000
H52.3 Anisometropia and aniseikonia	0.325	0.675	0.000
Y71 Cardiovascular devices associated with adverse incidents	0.324	0.676	0.000
Q06 Other congenital malformations of spinal cord	0.324	0.676	0.000
Q01 Encephalocele	0.324	0.676	0.000
Q00 Anencephaly and similar malformations	0.324	0.676	0.000
Q02 Microcephaly	0.324	0.676	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.324	0.676	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.323	0.677	0.000
Q82.9 Congenital malformation of skin, unspecified	0.323	0.677	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.323	0.677	0.000
Q82.3 Incontinentia pigmenti	0.323	0.677	0.000
Q82.2 Mastocytosis	0.323	0.677	0.000
Q82.1 Xeroderma pigmentosum	0.323	0.677	0.000
Q82.0 Hereditary lymphoedema	0.323	0.677	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.323	0.677	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.323	0.677	0.000
V40-V49 Car occupant injured in transport accident	0.323	0.677	0.000
H52.4 Presbyopia	0.323	0.677	0.000
Q52 Other congenital malformations of female genitalia	0.323	0.677	0.000
M84.0 Malunion of fracture	0.323	0.677	0.000
Q76.0 Spina bifida occulta	0.322	0.678	0.000
H11.9 Disorder of conjunctiva, unspecified	0.322	0.678	0.000
H15.8 Other disorders of sclera	0.322	0.678	0.000
E40-E46 Malnutrition	0.321	0.678	0.000
X59.2 School, other institution and public administrative area	0.321	0.679	0.000
M84.4 Pathological fracture, not elsewhere classified	0.321	0.679	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.320	0.679	0.000
H25.1 Senile nuclear cataract	0.320	0.680	0.000
M67.47 Ganglion, ankle and foot	0.320	0.680	0.000
H90 Conductive and sensorineural hearing loss	0.320	0.680	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.320	0.680	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.319	0.680	0.000
Q75 Other congenital malformations of skull and face bones	0.319	0.680	0.000
Q73 Reduction defects of unspecified limb	0.319	0.680	0.000
Q72 Reduction defects of lower limb	0.319	0.680	0.000
Q71 Reduction defects of upper limb	0.319	0.680	0.000
Q70 Syndactyly	0.319	0.680	0.000
Q69 Polydactyly	0.319	0.680	0.000
Q68 Other congenital musculoskeletal deformities	0.319	0.680	0.000
W08.0 Home	0.319	0.681	0.000
V98-V99 Other and unspecified transport accidents	0.319	0.681	0.000
M85.69 Other cyst of bone (Site unspecified)	0.319	0.681	0.000
M85.68 Other cyst of bone (Other)	0.319	0.681	0.000
M85.66 Other cyst of bone (Lower leg)	0.319	0.681	0.000
M85.64 Other cyst of bone (Hand)	0.319	0.681	0.000
M85.63 Other cyst of bone (Forearm)	0.319	0.681	0.000
M85.62 Other cyst of bone (Upper arm)	0.319	0.681	0.000
M85.61 Other cyst of bone (Shoulder region)	0.319	0.681	0.000
M85.60 Other cyst of bone (Multiple sites)	0.319	0.681	0.000
H16.2 Keratoconjunctivitis	0.319	0.681	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.318	0.681	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.318	0.681	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.318	0.681	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.318	0.681	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.318	0.681	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.318	0.681	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.318	0.681	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.318	0.681	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.318	0.681	0.000
E77 Disorders of glycoprotein metabolism	0.318	0.681	0.000
E76 Disorders of glycosaminoglycan metabolism	0.318	0.681	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.318	0.681	0.000
E72 Other disorders of amino-acid metabolism	0.318	0.681	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.318	0.681	0.000
E70 Disorders of aromatic amino-acid metabolism	0.318	0.681	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.318	0.681	0.000
W03.4 Street and highway	0.318	0.682	0.000
V09 Pedestrian injured in other and unspecified transport accidents	0.317	0.682	0.000
X51 Travel and motion	0.317	0.683	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.317	0.683	0.000
Q30 Congenital malformations of nose	0.317	0.683	0.000
W01 Fall on same level from slipping, tripping and stumbling	0.317	0.683	0.000
H10.3 Acute conjunctivitis, unspecified	0.317	0.683	0.000
H17 Corneal scars and opacities	0.316	0.684	0.000
W06 Fall involving bed	0.316	0.684	0.000
E79 Disorders of purine and pyrimidine metabolism	0.315	0.685	0.000
M48 Other spondylopathies	0.315	0.685	0.000
W15.8 Other specified place	0.315	0.685	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.315	0.685	0.000
M61 Calcification and ossification of muscle	0.315	0.685	0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.315	0.685	0.000
V01 Pedestrian injured in collision with pedal cycle	0.315	0.685	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.314	0.686	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.314	0.686	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.314	0.686	0.000
E89.5 Postprocedural testicular hypofunction	0.314	0.686	0.000
E89.1 Postprocedural hypoinsulinaemia	0.314	0.686	0.000
E89.4 Postprocedural ovarian failure	0.314	0.686	0.000
H15.9 Disorder of sclera, unspecified	0.314	0.686	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.313	0.687	0.000
W18 Other fall on same level	0.313	0.687	0.000
Q53 Undescended testicle	0.313	0.687	0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.312	0.687	0.000
H34.9 Retinal vascular occlusion, unspecified	0.312	0.688	0.000
Y82 Other and unspecified medical devices associated with adverse incidents	0.312	0.688	0.000
Y81 General- and plastic-surgery devices associated with adverse incidents	0.312	0.688	0.000
Y80 Physical medicine devices associated with adverse incidents	0.312	0.688	0.000
Y78 Radiological devices associated with adverse incidents	0.312	0.688	0.000
Y75 Neurological devices associated with adverse incidents	0.312	0.688	0.000
Y74 General hospital and personal-use devices associated with adverse incidents	0.312	0.688	0.000
Y72 Otorhinolaryngological devices associated with adverse incidents	0.312	0.688	0.000
Y70 Anaesthesiology devices associated with adverse incidents	0.312	0.688	0.000
H10.9 Conjunctivitis, unspecified	0.312	0.688	0.000
W60 Contact with plant thorns and spines and sharp leaves	0.312	0.688	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.312	0.688	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.312	0.688	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.312	0.688	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.312	0.688	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.312	0.688	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.312	0.688	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.312	0.688	0.000
H16.9 Keratitis, unspecified	0.312	0.688	0.000
Q60.2 Renal agenesis, unspecified	0.312	0.688	0.000
Q51.3 Bicornate uterus	0.311	0.689	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.311	0.689	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.311	0.689	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.311	0.689	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.311	0.689	0.000
Q85.1 Tuberous sclerosis	0.311	0.689	0.000
E83 Disorders of mineral metabolism	0.311	0.689	0.000
H30 Chorioretinal inflammation	0.311	0.689	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.310	0.689	0.000
X20-X29 Contact with venomous animals and plants	0.310	0.690	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.310	0.690	0.000
H72.2 Other marginal perforations of tympanic membrane	0.310	0.690	0.000
W00.5 Trade and service area	0.310	0.690	0.000
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.309	0.690	0.000
M00.9 Pyogenic arthritis, unspecified	0.309	0.691	0.000
H31.1 Choroidal degeneration	0.309	0.691	0.000
Q61.9 Cystic kidney disease, unspecified	0.309	0.691	0.000
Q61.8 Other cystic kidney diseases	0.309	0.691	0.000
Q61.4 Renal dysplasia	0.309	0.691	0.000
Q61.1 Polycystic kidney, infantile type	0.309	0.691	0.000
H70.8 Other mastoiditis and related conditions	0.308	0.692	0.000
H70.2 Petrositis	0.308	0.692	0.000
H70.0 Acute mastoiditis	0.308	0.692	0.000
Y79.3 Surgical instruments, materials and devices (including sutures)	0.308	0.692	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.307	0.693	0.000
W64 Exposure to other and unspecified animate mechanical forces	0.306	0.693	0.000
W07 Fall involving chair	0.307	0.693	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.306	0.694	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.306	0.694	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.305	0.694	0.000
H16.4 Corneal neovascularisation	0.305	0.695	0.000
H31.0 Chorioretinal scars	0.305	0.695	0.000
M65 Synovitis and tenosynovitis	0.305	0.695	0.000
H92.0 Otalgia	0.305	0.695	0.000
V79 Bus occupant injured in other and unspecified transport accidents	0.304	0.696	0.000
Q61.3 Polycystic kidney, unspecified	0.304	0.696	0.000
H43-H45 Disorders of vitreous body and globe	0.304	0.696	0.000
M67.0 Short Achilles tendon (acquired)	0.304	0.696	0.000
M91-M94 Chondropathies	0.302	0.698	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.302	0.698	0.000
W51 Striking against or bumped into by another person	0.301	0.699	0.000
H52.6 Other disorders of refraction	0.300	0.700	0.000
H52.5 Disorders of accommodation	0.300	0.700	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.299	0.700	0.000
H18.6 Keratoconus	0.299	0.701	0.000
W87 Exposure to unspecified electric current	0.299	0.701	0.000
W11.6 Industrial and construction area	0.298	0.702	0.000
M89.0 Algoneurodystrophy	0.298	0.702	0.000
V04 Pedestrian injured in collision with heavy transport vehicle or bus	0.298	0.702	0.000
W10 Fall on and from stairs and steps	0.298	0.702	0.000
H21 Other disorders of iris and ciliary body	0.298	0.702	0.000
Y77.3 Surgical instruments, materials and devices (including sutures)	0.298	0.702	0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.297	0.702	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations