TreeWAS – Variant ID: rs10808119

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I08 Multiple valve diseases	0.245	0.755	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.240	0.760	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.238	0.762	0.000
I08.0 Disorders of both mitral and aortic valves	0.220	0.780	0.000
I08.8 Other multiple valve diseases	0.205	0.794	0.000
I08.9 Multiple valve disease, unspecified	0.196	0.804	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.179	0.821	0.000
I05-I09 Chronic rheumatic heart diseases	0.167	0.833	0.000
I05 Rheumatic mitral valve diseases	0.144	0.856	0.000
I07 Rheumatic tricuspid valve diseases	0.133	0.867	0.000
I05.1 Rheumatic mitral insufficiency	0.127	0.873	0.000
I09 Other rheumatic heart diseases	0.127	0.873	0.000
I06 Rheumatic aortic valve diseases	0.113	0.887	0.000
I07.1 Tricuspid insufficiency	0.109	0.891	0.000
I05.0 Mitral stenosis	0.108	0.892	0.000
I05.8 Other mitral valve diseases	0.103	0.897	0.000
I05.2 Mitral stenosis with insufficiency	0.101	0.898	0.000
I05.9 Mitral valve disease, unspecified	0.101	0.899	0.000
I09.9 Rheumatic heart disease, unspecified	0.099	0.901	0.000
I07.9 Tricuspid valve disease, unspecified	0.096	0.904	0.000
I07.8 Other tricuspid valve diseases	0.096	0.904	0.000
I07.2 Tricuspid stenosis with insufficiency	0.096	0.904	0.000
I07.0 Tricuspid stenosis	0.096	0.904	0.000
I09.8 Other specified rheumatic heart diseases	0.091	0.908	0.000
I09.2 Chronic rheumatic pericarditis	0.091	0.908	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.091	0.908	0.000
I09.0 Rheumatic myocarditis	0.091	0.908	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.081	0.919	0.000
I06.8 Other rheumatic aortic valve diseases	0.081	0.919	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.081	0.919	0.000
I06.1 Rheumatic aortic insufficiency	0.080	0.920	0.000
I06.0 Rheumatic aortic stenosis	0.075	0.925	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.025	0.975	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.980	0.020
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.982	0.018
M23.8 Other internal derangements of knee	0.000	0.982	0.018
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.983	0.017
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.000	0.984	0.016
M23.80 Other internal derangements of knee (Multiple sites)	0.000	0.984	0.016
M23.2 Derangement of meniscus due to old tear or injury	0.000	0.984	0.016
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.985	0.015
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.000	0.987	0.013
M23.87 Other internal derangements of knee (Capsular ligament)	0.000	0.987	0.013
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.000	0.987	0.013
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.988	0.012
M23 Internal derangement of knee	0.000	0.988	0.012
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.000	0.989	0.011
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.989	0.011
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.000	0.989	0.011
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.011	0.989	0.000
M23.5 Chronic instability of knee	0.000	0.990	0.010
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.000	0.990	0.010
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.990	0.009
M23.4 Loose body in knee	0.000	0.991	0.009
M23.1 Discoid meniscus (congenital)	0.000	0.991	0.009
H01.0 Blepharitis	0.009	0.991	0.000
Y45.5 4-Aminophenol derivatives	0.009	0.991	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.000	0.991	0.009
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.991	0.009
Y45.2 Propionic acid derivatives	0.009	0.991	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.009	0.991	0.000
M23.49 Loose body in knee-Unspec lig/men	0.000	0.991	0.009
Y45.4 Antirheumatics	0.008	0.992	0.000
Y45.8 Other analgesics and antipyretics	0.008	0.992	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.000	0.992	0.008
Y45.1 Salicylates	0.008	0.992	0.000
M23.57 Chronic instability of knee (Capsular ligament)	0.000	0.993	0.007
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.000	0.993	0.007
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.000	0.993	0.007
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.993	0.007
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.993	0.007
M23.50 Chronic instability of knee (Multiple sites)	0.000	0.993	0.007
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.993	0.007
Y45.0 Opioids and related analgesics	0.007	0.993	0.000
Q21.0 Ventricular septal defect	0.007	0.993	0.000
M23.47 Loose body in knee-Capsular lig	0.000	0.993	0.007
M23.45 Loose body in knee-Pst hrn lat men	0.000	0.993	0.007
M23.42 Loose body in knee-Pst lig/hrn men	0.000	0.993	0.007
M23.46 Loose body in knee-O/unsp lat men	0.000	0.993	0.007
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.000	0.993	0.007
M23.40 Loose body in knee-Mult sites	0.000	0.993	0.007
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.000	0.993	0.006
M23.17 Discoid meniscus (congenital)-Capsular lig	0.000	0.993	0.006
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.000	0.993	0.006
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.993	0.006
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.993	0.006
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.993	0.006
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.993	0.006
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.000	0.993	0.006
M23.9 Internal derangement of knee, unspecified	0.000	0.993	0.006
M23.0 Cystic meniscus	0.000	0.994	0.006
M23.43 Loose body in knee-Med lig/oth men	0.000	0.994	0.006
M23.41 Loose body in knee-Ant lig/hrn men	0.000	0.994	0.006
O23.4 Unspecified infection of urinary tract in pregnancy	0.006	0.994	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.994	0.006
M23.44 Loose body in knee-Lat lig/ant men	0.000	0.994	0.006
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.994	0.006
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.000	0.994	0.006
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.000	0.994	0.006
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.000	0.994	0.006
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.994	0.006
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.994	0.006
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.994	0.006
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.000	0.994	0.006
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.994	0.005
Q21 Congenital malformations of cardiac septa	0.006	0.994	0.000
Q21.3 Tetralogy of Fallot	0.005	0.995	0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.000	0.995	0.005
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.000	0.995	0.005
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.000	0.995	0.005
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.000	0.995	0.005
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.995	0.005
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.995	0.005
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.995	0.005
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.000	0.995	0.005
M23.07 Cystic meniscus-Capsular lig	0.000	0.995	0.005
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.000	0.995	0.005
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.995	0.005
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.995	0.005
M23.00 Cystic meniscus (Multiple sites)	0.000	0.995	0.005
Z94.0 Kidney transplant status	0.005	0.995	0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.000	0.995	0.005
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.995	0.004
Q21.9 Congenital malformation of cardiac septum, unspecified	0.005	0.995	0.000
K80.4 Calculus of bile duct with cholecystitis	0.000	0.995	0.005
S61.9 Open wound of wrist and hand, part unspecified	0.005	0.995	0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.995	0.004
I27.0 Primary pulmonary hypertension	0.004	0.996	0.000
Q21.8 Other congenital malformations of cardiac septa	0.004	0.996	0.000
Q21.4 Aortopulmonary septal defect	0.004	0.996	0.000
Q21.2 Atrioventricular septal defect	0.004	0.996	0.000
D75.1 Secondary polycythaemia	0.004	0.996	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.004	0.996	0.000
Q61.2 Polycystic kidney, adult type	0.004	0.996	0.000
S80.8 Other superficial injuries of lower leg	0.000	0.996	0.004
D09.0 Bladder	0.004	0.996	0.000
C17.0 Duodenum	0.000	0.996	0.004
H01 Other inflammation of eyelid	0.004	0.996	0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.996	0.003
Q85.0 Neurofibromatosis (nonmalignant)	0.004	0.996	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.004	0.996	0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.996	0.003
Q23 Congenital malformations of aortic and mitral valves	0.004	0.996	0.000
Q27.3 Peripheral arteriovenous malformation	0.004	0.996	0.000
Y46.4 Iminostilbenes	0.004	0.996	0.000
Q85.9 Phakomatosis, unspecified	0.003	0.996	0.000
Q85 Phakomatoses, not elsewhere classified	0.003	0.996	0.000
S91.3 Open wound of other parts of foot	0.003	0.996	0.000
H01.8 Other specified inflammation of eyelid	0.003	0.997	0.000
Q27 Other congenital malformations of peripheral vascular system	0.003	0.997	0.000
D45 Polycythaemia vera	0.003	0.997	0.000
Z57.2 Occupational exposure to dust	0.003	0.997	0.000
Q24 Other congenital malformations of heart	0.003	0.997	0.000
Q26 Congenital malformations of great veins	0.003	0.997	0.000
Q25 Congenital malformations of great arteries	0.003	0.997	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
Q25.4 Other congenital malformations of aorta	0.003	0.997	0.000
Q23.1 Congenital insufficiency of aortic valve	0.003	0.997	0.000
E89.0 Postprocedural hypothyroidism	0.003	0.997	0.000
S80.0 Contusion of knee	0.000	0.997	0.003
Q22 Congenital malformations of pulmonary and tricuspid valves	0.003	0.997	0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.001	0.997	0.002
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.997	0.003
Q21.1 Atrial septal defect	0.003	0.997	0.000
Q24.6 Congenital heart block	0.003	0.997	0.000
Q24.4 Congenital subaortic stenosis	0.003	0.997	0.000
Q85.1 Tuberous sclerosis	0.003	0.997	0.000
Q23.3 Congenital mitral insufficiency	0.003	0.997	0.000
Q23.0 Congenital stenosis of aortic valve	0.003	0.997	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
H01.9 Inflammation of eyelid, unspecified	0.003	0.997	0.000
Q28 Other congenital malformations of circulatory system	0.003	0.997	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.003	0.997	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.003	0.997	0.000
Q23.4 Hypoplastic left heart syndrome	0.003	0.997	0.000
Q23.2 Congenital mitral stenosis	0.003	0.997	0.000
K09.2 Other cysts of jaw	0.000	0.997	0.003
S29.9 Unspecified injury of thorax	0.000	0.997	0.003
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.003	0.997	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.003	0.997	0.000
Q27.4 Congenital phlebectasia	0.003	0.997	0.000
Q27.2 Other congenital malformations of renal artery	0.003	0.997	0.000
Q27.1 Congenital renal artery stenosis	0.003	0.997	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.003	0.997	0.000
Q80-Q89 Other congenital malformations	0.003	0.997	0.000
Z57.3 Occupational exposure to other air contaminants	0.003	0.997	0.000
H73.8 Other specified disorders of tympanic membrane	0.000	0.997	0.003
Y46.5 Valproic acid	0.003	0.997	0.000
Q25.3 Stenosis of aorta	0.002	0.997	0.000
Q24.3 Pulmonary infundibular stenosis	0.002	0.997	0.000
Q24.2 Cor triatriatum	0.002	0.997	0.000
Q24.1 Levocardia	0.002	0.997	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.003	0.997	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.002	0.997	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.002	0.997	0.000
Q20.6 Isomerism of atrial appendages	0.002	0.997	0.000
Q20.5 Discordant atrioventricular connexion	0.002	0.997	0.000
Q20.4 Double inlet ventricle	0.002	0.997	0.000
Q20.3 Discordant ventriculoarterial connexion	0.002	0.997	0.000
Q20.2 Double outlet left ventricle	0.002	0.997	0.000
Q20.1 Double outlet right ventricle	0.002	0.997	0.000
Q20.0 Common arterial trunk	0.002	0.997	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.003	0.997	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.002	0.997	0.000
Q25.8 Other congenital malformations of great arteries	0.002	0.997	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.002	0.997	0.000
Q25.5 Atresia of pulmonary artery	0.002	0.997	0.000
Q25.2 Atresia of aorta	0.002	0.997	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.002	0.997	0.000
Q26.8 Other congenital malformations of great veins	0.002	0.997	0.000
Q26.6 Portal vein-hepatic artery fistula	0.002	0.997	0.000
Q26.5 Anomalous portal venous connexion	0.002	0.997	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.002	0.997	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.002	0.997	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.002	0.997	0.000
Q26.1 Persistent left superior vena cava	0.002	0.997	0.000
Q26.0 Congenital stenosis of vena cava	0.002	0.997	0.000
C17.1 Jejunum	0.000	0.997	0.003
S80 Superficial injury of lower leg	0.000	0.997	0.003
H01.1 Non-infectious dermatoses of eyelid	0.002	0.997	0.000
Q24.0 Dextrocardia	0.002	0.997	0.000
C17 Malignant neoplasm of small intestine	0.000	0.997	0.003
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)	0.002	0.997	0.000
M86.6 Other chronic osteomyelitis	0.003	0.997	0.000
Q61 Cystic kidney disease	0.002	0.997	0.000
Z57 Occupational exposure to risk-factors	0.003	0.997	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.002	0.997	0.000
Q22.5 Ebstein's anomaly	0.002	0.998	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.002	0.998	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.002	0.998	0.000
Q22.6 Hypoplastic right heart syndrome	0.002	0.998	0.000
Q22.4 Congenital tricuspid stenosis	0.002	0.998	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.002	0.998	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.002	0.998	0.000
Q22.0 Pulmonary valve atresia	0.002	0.998	0.000
Q50-Q56 Congenital malformations of genital organs	0.002	0.998	0.000
M86.69 Other chronic osteomyelitis (Site unspecified)	0.002	0.998	0.000
K11.2 Sialoadenitis	0.000	0.998	0.002
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.002	0.998	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.002	0.998	0.000
M86.66 Other chronic osteomyelitis (Lower leg)	0.002	0.998	0.000
Q25.0 Patent ductus arteriosus	0.002	0.998	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
Y51.0 Anticholinesterase agents	0.002	0.998	0.000
B35.1 Tinea unguium	0.002	0.998	0.000
Q25.1 Coarctation of aorta	0.002	0.998	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.002	0.998	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.002	0.998	0.000
Q28.1 Other malformations of precerebral vessels	0.002	0.998	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.002	0.998	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.002	0.998	0.000
Q25.6 Stenosis of pulmonary artery	0.002	0.998	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
G57.8 Other mononeuropathies of lower limb	0.000	0.998	0.002
H53.8 Other visual disturbances	0.000	0.998	0.002
Q51.8 Other congenital malformations of uterus and cervix	0.002	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.002	0.998	0.000
Q60-Q64 Congenital malformations of the urinary system	0.002	0.998	0.000
N08.5 Glomerular disorders in systemic connective tissue disorders	0.002	0.998	0.000
Y46.8 Antispasticity drugs	0.002	0.998	0.000
Y46.3 Deoxybarbiturates	0.002	0.998	0.000
Y46.1 Oxazolidinediones	0.002	0.998	0.000
Y46.0 Succinimides	0.002	0.998	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.000	0.998	0.002
H49.2 Sixth [abducent] nerve palsy	0.000	0.998	0.002
Q24.8 Other specified congenital malformations of heart	0.002	0.998	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.002	0.998	0.000
Q61.5 Medullary cystic kidney	0.002	0.998	0.000
S80.7 Multiple superficial injuries of lower leg	0.000	0.998	0.002
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.002	0.998	0.000
Q51 Congenital malformations of uterus and cervix	0.002	0.998	0.000
I21.9 Acute myocardial infarction, unspecified	0.002	0.998	0.000
Y46.2 Hydantoin derivatives	0.002	0.998	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.002	0.998	0.000
Q84 Other congenital malformations of integument	0.002	0.998	0.000
Q81 Epidermolysis bullosa	0.002	0.998	0.000
Q80 Congenital ichthyosis	0.002	0.998	0.000
Q00-Q07 Congenital malformations of the nervous system	0.002	0.998	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.002	0.998	0.000
Q54 Hypospadias	0.002	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.002	0.998	0.000
Q61.4 Renal dysplasia	0.002	0.998	0.000
C17.2 Ileum	0.000	0.998	0.002
T17.2 Foreign body in pharynx	0.002	0.998	0.000
Q83 Congenital malformations of breast	0.002	0.998	0.000
N76.0 Acute vaginitis	0.000	0.998	0.002
O14.9 Preeclampsia, unspecified	0.000	0.998	0.002
Q22.1 Congenital pulmonary valve stenosis	0.002	0.998	0.000
Z57.8 Occupational exposure to other risk-factors	0.002	0.998	0.000
Q07 Other congenital malformations of nervous system	0.002	0.998	0.000
Q83.1 Accessory breast	0.002	0.998	0.000
Q87.4 Marfan's syndrome	0.002	0.998	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.002	0.998	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.000	0.998	0.002
D09 Carcinoma in situ of other and unspecified sites	0.002	0.998	0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)	0.002	0.998	0.000
C17.8 Overlapping lesion of small intestine	0.000	0.998	0.002
C17.3 Meckel's diverticulum	0.000	0.998	0.002
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.998	0.002
Q24.5 Malformation of coronary vessels	0.002	0.998	0.000
Q54.8 Other hypospadias	0.002	0.998	0.000
M86.68 Other chronic osteomyelitis (Other)	0.002	0.998	0.000
M86.64 Other chronic osteomyelitis (Hand)	0.002	0.998	0.000
M86.63 Other chronic osteomyelitis (Forearm)	0.002	0.998	0.000
M86.62 Other chronic osteomyelitis (Upper arm)	0.002	0.998	0.000
M86.61 Other chronic osteomyelitis (Shoulder region)	0.002	0.998	0.000
M86.60 Other chronic osteomyelitis (Multiple sites)	0.002	0.998	0.000
Q28.3 Other malformations of cerebral vessels	0.002	0.998	0.000
Q61.8 Other cystic kidney diseases	0.002	0.998	0.000
Q61.1 Polycystic kidney, infantile type	0.002	0.998	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.002	0.998	0.000
Z57.7 Occupational exposure to vibration	0.002	0.998	0.000
Z57.6 Occupational exposure to extreme temperature	0.002	0.998	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.002	0.998	0.000
Z57.1 Occupational exposure to radiation	0.002	0.998	0.000
Z57.0 Occupational exposure to noise	0.002	0.998	0.000
Q52 Other congenital malformations of female genitalia	0.002	0.998	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.002	0.998	0.000
Q07.0 Arnold-Chiari syndrome	0.002	0.998	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.002	0.998	0.000
M13.93 Arthritis, unspecified (Forearm)	0.002	0.998	0.000
C17.9 Small intestine, unspecified	0.000	0.998	0.002
Q28.0 Arteriovenous malformation of precerebral vessels	0.002	0.998	0.000
Q37 Cleft palate with cleft lip	0.002	0.998	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.002	0.998	0.000
Q53 Undescended testicle	0.002	0.998	0.000
O36.5 Maternal care for poor foetal growth	0.000	0.998	0.002
Q54.0 Hypospadias, balanic	0.002	0.998	0.000
Q30 Congenital malformations of nose	0.002	0.998	0.000
G61.0 Guillain-Barre syndrome	0.002	0.998	0.000
I27.9 Pulmonary heart disease, unspecified	0.002	0.998	0.000
Q61.9 Cystic kidney disease, unspecified	0.002	0.998	0.000
D40.0 Prostate	0.000	0.998	0.002
I27 Other pulmonary heart diseases	0.002	0.998	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.002	0.998	0.000
D09.9 Carcinoma in situ, unspecified	0.002	0.998	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.998	0.002
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.002	0.998	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.002	0.998	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.002	0.998	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.002	0.998	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.000	0.998	0.002
O36.3 Maternal care for signs of foetal hypoxia	0.000	0.998	0.002
Q37.9 Unspecified cleft palate with unilateral cleft lip	0.002	0.998	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.998	0.002
Q99 Other chromosome abnormalities, not elsewhere classified	0.002	0.998	0.000
Q54.1 Hypospadias, penile	0.002	0.998	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.002	0.998	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.002	0.998	0.000
Q96 Turner's syndrome	0.002	0.998	0.000
Q07.8 Other specified congenital malformations of nervous system	0.002	0.998	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.002	0.998	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.002	0.998	0.000
Q51.6 Embryonic cyst of cervix	0.002	0.998	0.000
Q51.5 Agenesis and aplasia of cervix	0.002	0.998	0.000
Q51.3 Bicornate uterus	0.002	0.998	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.002	0.998	0.000
Q51.0 Agenesis and aplasia of uterus	0.002	0.998	0.000
Q06 Other congenital malformations of spinal cord	0.002	0.998	0.000
Q34 Other congenital malformations of respiratory system	0.002	0.998	0.000
Q33 Congenital malformations of lung	0.002	0.998	0.000
Q32 Congenital malformations of trachea and bronchus	0.002	0.998	0.000
Q63 Other congenital malformations of kidney	0.002	0.998	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.002	0.998	0.000
H49.1 Fourth [trochlear] nerve palsy	0.000	0.998	0.002
Q53.9 Undescended testicle, unspecified	0.002	0.998	0.000
Q80.9 Congenital ichthyosis, unspecified	0.002	0.998	0.000
Q80.8 Other congenital ichthyosis	0.002	0.998	0.000
Q80.4 Harlequin foetus	0.002	0.998	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.002	0.998	0.000
Q80.2 Lamellar ichthyosis	0.002	0.998	0.000
Q80.1 X-linked ichthyosis	0.002	0.998	0.000
Q80.0 Ichthyosis vulgaris	0.002	0.998	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.002	0.998	0.000
Q81.8 Other epidermolysis bullosa	0.002	0.998	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.002	0.998	0.000
Q81.1 Epidermolysis bullosa letalis	0.002	0.998	0.000
Q81.0 Epidermolysis bullosa simplex	0.002	0.998	0.000
Q84.9 Congenital malformation of integument, unspecified	0.002	0.998	0.000
Q84.8 Other specified congenital malformations of integument	0.002	0.998	0.000
Q84.6 Other congenital malformations of nails	0.002	0.998	0.000
Q84.5 Enlarged and hypertrophic nails	0.002	0.998	0.000
Q84.4 Congenital leukonychia	0.002	0.998	0.000
Q84.3 Anonychia	0.002	0.998	0.000
Q84.2 Other congenital malformations of hair	0.002	0.998	0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.002	0.998	0.000
Q84.0 Congenital alopecia	0.002	0.998	0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.002	0.998	0.000
Q86.2 Dysmorphism due to warfarin	0.002	0.998	0.000
Q86.1 Foetal hydantoin syndrome	0.002	0.998	0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.002	0.998	0.000
Q04 Other congenital malformations of brain	0.002	0.998	0.000
Q01 Encephalocele	0.002	0.998	0.000
Q00 Anencephaly and similar malformations	0.002	0.998	0.000
Q02 Microcephaly	0.002	0.998	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.002	0.998	0.000
Q54.4 Congenital chordee	0.002	0.998	0.000
Q54.3 Hypospadias, perineal	0.002	0.998	0.000
Q54.2 Hypospadias, penoscrotal	0.002	0.998	0.000
Q31 Congenital malformations of larynx	0.002	0.998	0.000
Q36 Cleft lip	0.002	0.998	0.000
Q55 Other congenital malformations of male genital organs	0.002	0.998	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.002	0.998	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.002	0.998	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.002	0.998	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.002	0.998	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.002	0.998	0.000
D09.1 Other and unspecified urinary organs	0.002	0.998	0.000
H69.8 Other specified disorders of Eustachian tube	0.000	0.998	0.002
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
Q30.9 Congenital malformation of nose, unspecified	0.002	0.998	0.000
Q51.4 Unicornate uterus	0.002	0.998	0.000
Q83.9 Congenital malformation of breast, unspecified	0.002	0.998	0.000
Q83.2 Absent nipple	0.002	0.998	0.000
Q83.0 Congenital absence of breast with absent nipple	0.002	0.998	0.000
H49 Paralytic strabismus	0.000	0.998	0.002
E27.3 Drug-induced adrenocortical insufficiency	0.002	0.998	0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.002	0.998	0.000
M86 Osteomyelitis	0.002	0.998	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.998	0.000
Q07.9 Congenital malformation of nervous system, unspecified	0.002	0.998	0.000
Z97.5 Presence of (intra-uterine) contraceptive device	0.000	0.998	0.002
Q89 Other congenital malformations, not elsewhere classified	0.002	0.998	0.000
M89.04 Algoneurodystrophy (Hand)	0.002	0.998	0.000
D09.7 Carcinoma in situ of other specified sites	0.002	0.998	0.000
D09.3 Thyroid and other endocrine glands	0.002	0.998	0.000
D09.2 Eye	0.002	0.998	0.000
H49.0 Third [oculomotor] nerve palsy	0.000	0.998	0.002
Q63.0 Accessory kidney	0.002	0.998	0.000
Q03 Congenital hydrocephalus	0.002	0.998	0.000
M90.10 Periostitis in other infectious diseases classified elsewhere (Multiple sites)	0.000	0.998	0.002
M90.78 Fracture of bone in neoplastic disease (Other)	0.000	0.998	0.002
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.002	0.998	0.000
Q52.4 Other congenital malformations of vagina	0.002	0.998	0.000
Q52.1 Doubling of vagina	0.002	0.998	0.000
Q78.0 Osteogenesis imperfecta	0.002	0.998	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.002	0.998	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.002	0.998	0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.002	0.998	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.002	0.998	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.002	0.998	0.000
Q52.7 Other congenital malformations of vulva	0.002	0.998	0.000
Q52.6 Congenital malformation of clitoris	0.002	0.998	0.000
Q52.3 Imperforate hymen	0.002	0.998	0.000
Q52.2 Congenital rectovaginal fistula	0.002	0.998	0.000
Q52.0 Congenital absence of vagina	0.002	0.998	0.000
M50.2 Other cervical disk displacement	0.002	0.998	0.000
Q37.8 Unspecified cleft palate with bilateral cleft lip	0.001	0.998	0.000
Q37.5 Cleft hard and soft palate with unilateral cleft lip	0.001	0.998	0.000
Q37.4 Cleft hard and soft palate with bilateral cleft lip	0.001	0.998	0.000
Q37.3 Cleft soft palate with unilateral cleft lip	0.001	0.998	0.000
Q37.2 Cleft soft palate with bilateral cleft lip	0.001	0.998	0.000
Q37.1 Cleft hard palate with unilateral cleft lip	0.001	0.998	0.000
Q37.0 Cleft hard palate with bilateral cleft lip	0.001	0.998	0.000
Q53.0 Ectopic testis	0.002	0.998	0.000
H73 Other disorders of tympanic membrane	0.000	0.998	0.002
Q64 Other congenital malformations of urinary system	0.002	0.998	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
Q30.8 Other congenital malformations of nose	0.001	0.998	0.000
Q30.3 Congenital perforated nasal septum	0.001	0.998	0.000
Q30.2 Fissured, notched and cleft nose	0.001	0.998	0.000
Q30.1 Agenesis and underdevelopment of nose	0.001	0.998	0.000
Q30.0 Choanal atresia	0.001	0.998	0.000
Q50.5 Embryonic cyst of broad ligament	0.002	0.998	0.000
Q52.5 Fusion of labia	0.002	0.998	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.002	0.998	0.000
Q56.4 Indeterminate sex, unspecified	0.001	0.998	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.001	0.998	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.001	0.998	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.001	0.998	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.001	0.998	0.000
Q35 Cleft palate	0.001	0.998	0.000
Q82 Other congenital malformations of skin	0.002	0.998	0.000
Q90 Down's syndrome	0.001	0.998	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.002	0.998	0.000
I27.1 Kyphoscoliotic heart disease	0.002	0.998	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.002	0.998	0.000
Q99.8 Other specified chromosome abnormalities	0.002	0.998	0.000
M86.9 Osteomyelitis, unspecified	0.002	0.998	0.000
Q15 Other congenital malformations of eye	0.002	0.998	0.000
M86.94 Osteomyelitis, unspecified (Hand)	0.002	0.998	0.000
Q82.0 Hereditary lymphoedema	0.002	0.998	0.000
Q96.9 Turner's syndrome, unspecified	0.001	0.998	0.000
Q98.4 Klinefelter's syndrome, unspecified	0.001	0.998	0.000
Y57.5 X-ray contrast media	0.000	0.998	0.002
Q18 Other congenital malformations of face and neck	0.002	0.998	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.002	0.998	0.000
Q14 Congenital malformations of posterior segment of eye	0.002	0.998	0.000
Q13 Congenital malformations of anterior segment of eye	0.002	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
M86.47 Chronic osteomyelitis with draining sinus (Ankle and foot)	0.002	0.998	0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.002	0.998	0.000
H49.8 Other paralytic strabismus	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations