TreeWAS – Variant ID: rs10838687

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.000	0.010	0.990
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.595	0.405	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.595	0.405	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.587	0.413	0.000
C91 Lymphoid leukaemia	0.557	0.443	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.556	0.444	0.000
C85.1 B-cell lymphoma, unspecified	0.546	0.454	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.521	0.479	0.000
C95 Leukaemia of unspecified cell type	0.510	0.490	0.000
C91.0 Acute lymphoblastic leukaemia	0.504	0.496	0.000
C91.1 Chronic lymphocytic leukaemia	0.503	0.497	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.475	0.525	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.474	0.526	0.000
C82.2 Large cell, follicular	0.466	0.534	0.000
C93 Monocytic leukaemia	0.454	0.546	0.000
C88 Malignant immunoproliferative diseases	0.453	0.547	0.000
C82.3 Follicular lymphoma grade IIIa	0.452	0.548	0.000
C86 Other specified types of T/NK-cell lymphoma	0.449	0.551	0.000
C82.4 Follicular lymphoma grade IIIb	0.446	0.554	0.000
C83.0 Small cell (diffuse)	0.434	0.566	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.431	0.569	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.429	0.571	0.000
C82.6 Cutaneous follicle centre lymphoma	0.426	0.573	0.000
C82.5 Diffuse follicle centre lymphoma	0.426	0.573	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.421	0.579	0.000
C94 Other leukaemias of specified cell type	0.421	0.579	0.000
C95.9 Leukaemia, unspecified	0.409	0.591	0.000
C91.5 Adult T-cell leukaemia	0.405	0.595	0.000
C91.9 Lymphoid leukaemia, unspecified	0.400	0.600	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.400	0.600	0.000
C91.7 Other lymphoid leukaemia	0.400	0.600	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.400	0.600	0.000
C91.3 Prolymphocytic leukaemia	0.400	0.600	0.000
C91.2 Subacute lymphocytic leukaemia	0.400	0.600	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.399	0.601	0.000
C85.0 Lymphosarcoma	0.399	0.601	0.000
C82.0 Small cleaved cell, follicular	0.395	0.604	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.391	0.609	0.000
C90.2 Plasmacytoma, extramedullary	0.387	0.613	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.372	0.628	0.000
C91.4 Hairy-cell leukaemia	0.368	0.632	0.000
C95.7 Other leukaemia of unspecified cell type	0.366	0.634	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.366	0.634	0.000
C95.0 Acute leukaemia of unspecified cell type	0.366	0.634	0.000
C90.1 Plasma cell leukaemia	0.364	0.636	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.362	0.638	0.000
C93.1 Chronic monocytic leukaemia	0.359	0.641	0.000
C83.3 Large cell (diffuse)	0.350	0.650	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.350	0.650	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.346	0.654	0.000
C83.6 Undifferentiated (diffuse)	0.340	0.660	0.000
C83.5 Lymphoblastic (diffuse)	0.340	0.660	0.000
C83.4 Immunoblastic (diffuse)	0.340	0.660	0.000
C83.2 Mixed small and large cell (diffuse)	0.340	0.660	0.000
C90.0 Multiple myeloma	0.340	0.660	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.328	0.672	0.000
C92 Myeloid leukaemia	0.328	0.672	0.000
C93.9 Monocytic leukaemia, unspecified	0.325	0.674	0.000
C93.7 Other monocytic leukaemia	0.325	0.674	0.000
C93.3 Juvenile myelomonocytic leukaemia	0.325	0.674	0.000
C93.2 Subacute monocytic leukaemia	0.325	0.674	0.000
C93.0 Acute monocytic leukaemia	0.325	0.674	0.000
C90.3 Solitary plasmacytoma	0.325	0.675	0.000
C88.9 Malignant immunoproliferative disease, unspecified	0.325	0.675	0.000
C88.7 Other malignant immunoproliferative diseases	0.325	0.675	0.000
C88.3 Immunoproliferative small intestinal disease	0.325	0.675	0.000
C88.2 Gamma heavy chain disease	0.325	0.675	0.000
C88.1 Alpha heavy chain disease	0.325	0.675	0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.322	0.678	0.000
C86.4 Blastic NK-cell lymphoma	0.322	0.678	0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.322	0.678	0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.322	0.678	0.000
C86.1 Hepatosplenic T-cell lymphoma	0.322	0.678	0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.322	0.678	0.000
C81 Hodgkin's disease	0.319	0.681	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.318	0.682	0.000
C83.7 Burkitt's tumour	0.308	0.692	0.000
C94.7 Other specified leukaemias	0.302	0.698	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.302	0.698	0.000
C94.5 Acute myelofibrosis	0.302	0.698	0.000
C94.4 Acute panmyelosis	0.302	0.698	0.000
C94.3 Mast cell leukaemia	0.302	0.698	0.000
C94.2 Acute megakaryoblastic leukaemia	0.302	0.698	0.000
C94.1 Chronic erythraemia	0.302	0.698	0.000
C94.0 Acute erythraemia and erythroleukaemia	0.302	0.698	0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.302	0.698	0.000
C96.8 Histiocytic sarcoma	0.302	0.698	0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.302	0.698	0.000
C96.6 Unifocal Langerhans-cell histiocytosis	0.302	0.698	0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.302	0.698	0.000
C96.4 Sarcoma of dendritic cells (accessory cells)	0.302	0.698	0.000
C96.3 True histiocytic lymphoma	0.302	0.698	0.000
C96.2 Malignant mast cell tumour	0.302	0.698	0.000
C96.1 Malignant histiocytosis	0.302	0.698	0.000
C96.0 Letterer-Siwe disease	0.302	0.698	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.301	0.698	0.000
C84.5 Other and unspecified T-cell lymphomas	0.288	0.711	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.280	0.719	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.280	0.719	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.280	0.719	0.000
C84.3 Lymphoepithelioid lymphoma	0.280	0.719	0.000
C84.2 T-zone lymphoma	0.280	0.719	0.000
C84.1 Sezary's diease	0.280	0.719	0.000
C84.0 Mycosis fungoides	0.280	0.719	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.277	0.723	0.000
C92.1 Chronic myeloid leukaemia	0.255	0.745	0.000
C84.4 Peripheral T-cell lymphoma	0.244	0.756	0.000
C92.9 Myeloid leukaemia, unspecified	0.241	0.759	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.235	0.764	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.235	0.764	0.000
C92.5 Acute myelomonocytic leukaemia	0.235	0.764	0.000
C92.3 Myeloid sarcoma	0.235	0.764	0.000
C92.2 Subacute myeloid leukaemia	0.235	0.764	0.000
C92.7 Other myeloid leukaemia	0.233	0.766	0.000
C81.2 Mixed cellularity	0.232	0.768	0.000
C81.7 Other Hodgkin's disease	0.229	0.771	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.229	0.771	0.000
C81.3 Lymphocytic depletion	0.229	0.771	0.000
C92.4 Acute promyelocytic leukaemia	0.227	0.772	0.000
C83.1 Small cleaved cell (diffuse)	0.219	0.781	0.001
C81.9 Hodgkin's disease, unspecified	0.210	0.790	0.000
I10-I15 Hypertensive diseases	0.000	0.801	0.199
C81.1 Nodular sclerosis	0.197	0.802	0.000
C81.0 Lymphocytic predominance	0.196	0.804	0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.163	0.837	0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.162	0.838	0.000
K40 Inguinal hernia	0.159	0.841	0.000
I13 Hypertensive heart and renal disease	0.000	0.857	0.143
I11 Hypertensive heart disease	0.000	0.858	0.142
I15 Secondary hypertension	0.000	0.871	0.129
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene	0.124	0.876	0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene	0.122	0.878	0.000
K40.1 Bilateral inguinal hernia, with gangrene	0.114	0.886	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.894	0.106
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.897	0.102
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.897	0.102
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.897	0.102
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.897	0.102
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.103	0.897	0.000
C92.0 Acute myeloid leukaemia	0.101	0.898	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.903	0.097
I15.1 Hypertension secondary to other renal disorders	0.000	0.904	0.096
I15.8 Other secondary hypertension	0.000	0.907	0.093
I15.2 Hypertension secondary to endocrine disorders	0.000	0.907	0.093
I15.0 Renovascular hypertension	0.000	0.912	0.087
I15.9 Seconday hypertension, unspecified	0.000	0.918	0.082
I12 Hypertensive renal disease	0.000	0.929	0.071
H40.9 Glaucoma, unspecified	0.041	0.959	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.962	0.038
I83.0 Varicose veins of lower extremities with ulcer	0.037	0.963	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.964	0.036
D22.3 Melanocytic naevi of other and unspecified parts of face	0.000	0.965	0.035
I83 Varicose veins of lower extremities	0.023	0.977	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.021	0.979	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.020	0.980	0.000
K40-K46 Hernia	0.016	0.984	0.000
I12.9 Hypertensive renal disease without renal failure	0.001	0.985	0.015
E03 Other hypothyroidism	0.000	0.985	0.015
K41 Femoral hernia	0.013	0.987	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.987	0.013
K45 Other abdominal hernia	0.011	0.988	0.000
E03.5 Myxoedema coma	0.000	0.989	0.011
E03.4 Atrophy of thyroid (acquired)	0.000	0.989	0.011
E03.3 Postinfectious hypothyroidism	0.000	0.989	0.011
E03.1 Congenital hypothyroidism without goitre	0.000	0.989	0.011
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.989	0.011
K43 Ventral hernia	0.011	0.989	0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.011	0.989	0.000
C43.5 Malignant melanoma of trunk	0.000	0.989	0.011
H40 Glaucoma	0.011	0.989	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.011	0.989	0.000
H40.1 Primary open-angle glaucoma	0.011	0.989	0.000
K45.0 Other specified abdominal hernia with obstruction, without gangrene	0.010	0.990	0.000
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.010	0.990	0.000
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.010	0.990	0.000
K41.1 Bilateral femoral hernia, with gangrene	0.010	0.990	0.000
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.010	0.990	0.000
K43.9 Ventral hernia without obstruction or gangrene	0.009	0.991	0.000
C43.4 Malignant melanoma of scalp and neck	0.000	0.991	0.009
K45.1 Other specified abdominal hernia with gangrene	0.008	0.991	0.000
H40.4 Glaucoma secondary to eye inflammation	0.008	0.991	0.000
K43.7 Other and unspecified ventral hernia with gangrene	0.008	0.992	0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene	0.008	0.992	0.000
K43.5 Parastomal hernia without obstruction or gangrene	0.008	0.992	0.000
K43.4 Parastomal hernia with gangrene	0.008	0.992	0.000
K43.3 Parastomal hernia with obstruction, without gangrene	0.008	0.992	0.000
K43.2 Incisional hernia without obstruction or gangrene	0.008	0.992	0.000
K43.1 Ventral hernia with gangrene	0.008	0.992	0.000
H40.6 Glaucoma secondary to drugs	0.008	0.992	0.000
H40.3 Glaucoma secondary to eye trauma	0.008	0.992	0.000
C43 Malignant melanoma of skin	0.000	0.992	0.008
K46 Unspecified abdominal hernia	0.007	0.992	0.001
K44 Diaphragmatic hernia	0.008	0.992	0.000
H00.0 Hordeolum and other deep inflammation of eyelid	0.000	0.993	0.007
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.993	0.007
E03.8 Other specified hypothyroidism	0.000	0.993	0.007
C43.9 Malignant melanoma of skin, unspecified	0.000	0.993	0.007
H40.5 Glaucoma secondary to other eye disorders	0.007	0.993	0.000
Z63.4 Disappearance and death of family member	0.000	0.993	0.007
I81 Portal vein thrombosis	0.006	0.994	0.000
H00.1 Chalazion	0.000	0.994	0.006
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.006	0.994	0.000
Y84.2 Radiological procedure and radiotherapy	0.006	0.994	0.000
H00 Hordeolum and chalazion	0.000	0.994	0.006
C43.8 Overlapping malignant melanoma of skin	0.000	0.994	0.006
C43.1 Malignant melanoma of eyelid, including canthus	0.000	0.994	0.006
C43.0 Malignant melanoma of lip	0.000	0.994	0.006
K46.1 Unspecified abdominal hernia with gangrene	0.005	0.994	0.001
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.006	0.994	0.000
K44.1 Diaphragmatic hernia with gangrene	0.006	0.994	0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene	0.005	0.994	0.001
H40.8 Other glaucoma	0.006	0.994	0.000
Z94.8 Other transplanted organ and tissue status	0.006	0.994	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.994	0.005
C43.2 Malignant melanoma of ear and external auricular canal	0.000	0.995	0.005
K43.0 Ventral hernia with obstruction, without gangrene	0.005	0.995	0.000
F32.1 Moderate depressive episode	0.000	0.995	0.005
C73 Malignant neoplasm of thyroid gland	0.000	0.995	0.005
Y84.6 Urinary catheterisation	0.005	0.995	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.005	0.995	0.000
M34.9 Systemic sclerosis, unspecified	0.005	0.995	0.000
R22.0 Localised swelling, mass and lump, head	0.005	0.995	0.000
H44.2 Degenerative myopia	0.000	0.995	0.005
Z63.0 Problems in relationship with spouse or partner	0.000	0.995	0.005
Z63 Other problems related to primary support group, including family circumstances	0.000	0.995	0.005
Z13.6 Special screening examination for cardiovascular disorders	0.000	0.995	0.005
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.005	0.995	0.000
Z63.5 Disruption of family by separation and divorce	0.000	0.995	0.005
H40-H42 Glaucoma	0.005	0.995	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.005	0.995	0.000
I87 Other disorders of veins	0.005	0.995	0.000
F32.0 Mild depressive episode	0.000	0.996	0.004
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.996	0.004
F32 Depressive episode	0.000	0.996	0.004
O47.0 False labour before 37 completed weeks of gestation	0.000	0.996	0.004
K42 Umbilical hernia	0.004	0.996	0.000
I88 Nonspecific lymphadenitis	0.004	0.996	0.000
M34.1 CR(E)ST syndrome	0.004	0.996	0.000
Z91.5 Personal history of self-harm	0.000	0.996	0.004
Y84.1 Kidney dialysis	0.004	0.996	0.000
I82 Other venous embolism and thrombosis	0.004	0.996	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.004	0.996	0.000
Y43.3 Other antineoplastic drugs	0.004	0.996	0.000
Y84.4 Aspiration of fluid	0.004	0.996	0.000
F32.8 Other depressive episodes	0.000	0.996	0.004
Z63.9 Problem related to primary support group, unspecified	0.000	0.996	0.004
Z63.3 Absence of family member	0.000	0.996	0.004
Z63.2 Inadequate family support	0.000	0.996	0.004
Z63.1 Problems in relationship with parents and in-laws	0.000	0.996	0.004
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.004	0.996	0.000
E06.3 Autoimmune thyroiditis	0.000	0.996	0.004
Y84.9 Medical procedure, unspecified	0.004	0.996	0.000
Y84.3 Shock therapy	0.003	0.996	0.000
M34 Systemic sclerosis	0.004	0.996	0.000
Y84.7 Blood-sampling	0.003	0.996	0.000
Y84.5 Insertion of gastric or duodenal sound	0.003	0.996	0.000
H42 Glaucoma in diseases classified elsewhere	0.003	0.996	0.000
I87.9 Disorder of vein, unspecified	0.003	0.996	0.000
I87.0 Postphlebitic syndrome	0.003	0.996	0.000
Y84.0 Cardiac catheterisation	0.004	0.996	0.000
Z63.6 Dependent relative needing care at home	0.000	0.997	0.003
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.997	0.003
I82.9 Embolism and thrombosis of unspecified vein	0.003	0.997	0.000
Z63.8 Other specified problems related to primary support group	0.000	0.997	0.003
I88.9 Nonspecific lymphadenitis, unspecified	0.003	0.997	0.000
I87.1 Compression of vein	0.003	0.997	0.000
I82.3 Embolism and thrombosis of renal vein	0.003	0.997	0.000
Z94 Transplanted organ and tissue status	0.003	0.997	0.000
S80.9 Superficial injury of lower leg, unspecified	0.000	0.997	0.003
K42.1 Umbilical hernia with gangrene	0.003	0.997	0.000
I86 Varicose veins of other sites	0.003	0.997	0.000
Z94.7 Corneal transplant status	0.003	0.997	0.000
I34.1 Mitral (valve) prolapse	0.003	0.997	0.000
I88.8 Other nonspecific lymphadenitis	0.003	0.997	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.003	0.997	0.000
I88.0 Nonspecific mesenteric lymphadenitis	0.003	0.997	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.003	0.997	0.000
I87.8 Other specified disorders of veins	0.003	0.997	0.000
D14.0 Middle ear, nasal cavity and accessory sinuses	0.000	0.997	0.003
N35.9 Urethral stricture, unspecified	0.000	0.997	0.003
D86 Sarcoidosis	0.000	0.997	0.003
R27.0 Ataxia, unspecified	0.000	0.997	0.003
I82.1 Thrombophlebitis migrans	0.003	0.997	0.000
I82.0 Budd-Chiari syndrome	0.003	0.997	0.000
O00.9 Ectopic pregnancy, unspecified	0.003	0.997	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.003	0.997	0.000
I82.2 Embolism and thrombosis of vena cava	0.003	0.997	0.000
D86.0 Sarcoidosis of lung	0.000	0.997	0.003
K57.3 Diverticular disease of large intestine without perforation or abscess	0.003	0.997	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.003	0.997	0.000
Z94.9 Transplanted organ and tissue status, unspecified	0.003	0.997	0.000
Q05.9 Spina bifida, unspecified	0.000	0.997	0.003
I85 Oesophageal varices	0.003	0.997	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.003	0.997	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.003	0.997	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.003	0.997	0.000
M34.0 Progressive systemic sclerosis	0.003	0.997	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.003	0.997	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.003	0.997	0.000
T80.2 Infections following infusion, transfusion and therapeutic injection	0.003	0.997	0.000
Z94.0 Kidney transplant status	0.003	0.997	0.000
I86.1 Scrotal varices	0.003	0.997	0.000
Z63.7 Other stressful life events affecting family and household	0.000	0.997	0.003
H44 Disorders of globe	0.000	0.997	0.003
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.001	0.997	0.002
M34.8 Other forms of systemic sclerosis	0.003	0.997	0.000
E06 Thyroiditis	0.000	0.997	0.003
H18.9 Disorder of cornea, unspecified	0.003	0.997	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.997	0.003
D45 Polycythaemia vera	0.003	0.997	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.003	0.997	0.000
Z94.6 Bone transplant status	0.003	0.997	0.000
Z94.5 Skin transplant status	0.003	0.997	0.000
Z94.3 Heart and lungs transplant status	0.003	0.997	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.003	0.997	0.000
I86.2 Pelvic varices	0.002	0.997	0.000
I86.0 Sublingual varices	0.002	0.997	0.000
H44.0 Purulent endophthalmitis	0.000	0.997	0.003
H44.1 Other endophthalmitis	0.000	0.997	0.003
Y45.8 Other analgesics and antipyretics	0.003	0.997	0.000
Z94.4 Liver transplant status	0.003	0.997	0.000
I86.3 Vulval varices	0.002	0.997	0.000
H49.2 Sixth [abducent] nerve palsy	0.003	0.997	0.000
S10.9 Superficial injury of neck, part unspecified	0.000	0.997	0.002
I85.0 Oesophageal varices with bleeding	0.002	0.997	0.000
R22.9 Localised swelling, mass and lump, unspecified	0.003	0.997	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.997	0.002
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.002	0.997	0.000
C50.3 Lower-inner quadrant of breast	0.002	0.998	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.998	0.002
D86.1 Sarcoidosis of lymph nodes	0.000	0.998	0.002
L40.5 Arthropathic psoriasis	0.000	0.998	0.002
N85.9 Noninflammatory disorder of uterus, unspecified	0.000	0.998	0.002
H40.0 Glaucoma suspect	0.002	0.998	0.000
H18.4 Corneal degeneration	0.002	0.998	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.000	0.998	0.002
Z43.3 Attention to colostomy	0.002	0.998	0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.002	0.998	0.000
Z94.1 Heart transplant status	0.002	0.998	0.000
D86.3 Sarcoidosis of skin	0.000	0.998	0.002
J01.9 Acute sinusitis, unspecified	0.000	0.998	0.002
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
I86.8 Varicose veins of other specified sites	0.002	0.998	0.000
O00.1 Tubal pregnancy	0.002	0.998	0.000
E14.9 Without complications	0.000	0.998	0.002
E14.3 With ophthalmic complications	0.000	0.998	0.002
H44.8 Other disorders of globe	0.000	0.998	0.002
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.000	0.998	0.002
H44.6 Retained (old) intraocular foreign body, magnetic	0.000	0.998	0.002
H44.3 Other degenerative disorders of globe	0.000	0.998	0.002
R22.1 Localised swelling, mass and lump, neck	0.002	0.998	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
E06.9 Thyroiditis, unspecified	0.000	0.998	0.002
N80.1 Endometriosis of ovary	0.002	0.998	0.000
H18 Other disorders of cornea	0.002	0.998	0.000
E06.5 Other chronic thyroiditis	0.000	0.998	0.002
E06.4 Drug-induced thyroiditis	0.000	0.998	0.002
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.998	0.002
E06.0 Acute thyroiditis	0.000	0.998	0.002
E00-E07 Disorders of thyroid gland	0.000	0.998	0.002
Z94.2 Lung transplant status	0.002	0.998	0.000
D86.8 Sarcoidosis of other and combined sites	0.000	0.998	0.002
H44.5 Degenerated conditions of globe	0.000	0.998	0.002
S80.8 Other superficial injuries of lower leg	0.000	0.998	0.002
D48.0 Bone and articular cartilage	0.002	0.998	0.000
H18.8 Other specified disorders of cornea	0.002	0.998	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.998	0.002
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.002	0.998	0.000
H16.9 Keratitis, unspecified	0.002	0.998	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
T43.6 Psychostimulants with abuse potential	0.000	0.998	0.002
H49.1 Fourth [trochlear] nerve palsy	0.002	0.998	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.998	0.002
M89.5 Osteolysis	0.002	0.998	0.000
C74 Malignant neoplasm of adrenal gland	0.000	0.998	0.002
O00 Ectopic pregnancy	0.002	0.998	0.000
R22.7 Localised swelling, mass and lump, multiple sites	0.002	0.998	0.000
S19.9 Unspecified injury of neck	0.000	0.998	0.002
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.002	0.998	0.000
E06.1 Subacute thyroiditis	0.000	0.998	0.002
H44.9 Disorder of globe, unspecified	0.000	0.998	0.002
K05.3 Chronic periodontitis	0.000	0.998	0.002
D48.5 Skin	0.002	0.998	0.000
I86.4 Gastric varices	0.002	0.998	0.000
H44.4 Hypotony of eye	0.000	0.998	0.002
H18.0 Corneal pigmentations and deposits	0.002	0.998	0.000
H49 Paralytic strabismus	0.002	0.998	0.000
H49.9 Paralytic strabismus, unspecified	0.002	0.998	0.000
H93.1 Tinnitus	0.000	0.998	0.002
S12.1 Fracture of second cervical vertebra	0.002	0.998	0.000
Y45.5 4-Aminophenol derivatives	0.002	0.998	0.000
Z43.4 Attention to other artificial openings of digestive tract	0.002	0.998	0.000
H16 Keratitis	0.002	0.998	0.000
H18.1 Bullous keratopathy	0.002	0.998	0.000
T43.9 Psychotropic drug, unspecified	0.000	0.998	0.002
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.998	0.002
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.998	0.002
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
C75 Malignant neoplasm of other endocrine glands and related structures	0.000	0.998	0.002
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.998	0.002
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.002	0.998	0.000
H18.2 Other corneal oedema	0.002	0.998	0.000
N88.9 Noninflammatory disorder of cervix uteri, unspecified	0.000	0.998	0.002
T80.6 Other serum reactions	0.002	0.998	0.000
T80.5 Anaphylactic shock due to serum	0.002	0.998	0.000
T80.4 Rh incompatibility reaction	0.002	0.998	0.000
T80.3 ABO incompatibility reaction	0.002	0.998	0.000
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
S80 Superficial injury of lower leg	0.000	0.998	0.002
H18.7 Other corneal deformities	0.002	0.998	0.000
H18.3 Changes in corneal membranes	0.002	0.998	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.002	0.998	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.998	0.002
E00 Congenital iodine-deficiency syndrome	0.000	0.998	0.002
C74.9 Adrenal gland, unspecified	0.000	0.998	0.002
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.000	0.998	0.002
M89.0 Algoneurodystrophy	0.002	0.998	0.000
Y43 Primarily systemic agents	0.002	0.998	0.000
K42.0 Umbilical hernia with obstruction, without gangrene	0.002	0.998	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.002	0.998	0.000
M89.04 Algoneurodystrophy (Hand)	0.002	0.998	0.000
R20.2 Paraesthesia of skin	0.000	0.998	0.002
Q05 Spina bifida	0.000	0.998	0.002
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.000	0.998	0.002
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.002	0.998	0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.002	0.998	0.000
G82.5 Tetraplegia, unspecified	0.000	0.998	0.002
M89.59 Osteolysis (Site unspecified)	0.002	0.998	0.000
M89.58 Osteolysis (Other)	0.002	0.998	0.000
M89.57 Osteolysis (Ankle and foot)	0.002	0.998	0.000
M89.56 Osteolysis (Lower leg)	0.002	0.998	0.000
M89.54 Osteolysis (Hand)	0.002	0.998	0.000
M89.53 Osteolysis (Forearm)	0.002	0.998	0.000
M89.52 Osteolysis (Upper arm)	0.002	0.998	0.000
M89.51 Osteolysis (Shoulder region)	0.002	0.998	0.000
M89.50 Osteolysis (Multiple sites)	0.002	0.998	0.000
C74.1 Medulla of adrenal gland	0.000	0.998	0.002
C74.0 Cortex of adrenal gland	0.000	0.998	0.002
G40.5 Special epileptic syndromes	0.000	0.998	0.002
H16.2 Keratoconjunctivitis	0.002	0.998	0.000
O00.8 Other ectopic pregnancy	0.002	0.998	0.000
O00.2 Ovarian pregnancy	0.002	0.998	0.000
O00.0 Abdominal pregnancy	0.002	0.998	0.000
Y47.1 Benzodiazepines	0.002	0.998	0.000
H16.0 Corneal ulcer	0.002	0.998	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.998	0.001
D48.7 Other specified sites	0.002	0.998	0.000
Y45.0 Opioids and related analgesics	0.002	0.998	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.002	0.998	0.000
M89.03 Algoneurodystrophy (Forearm)	0.002	0.998	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.998	0.002
G40.8 Other epilepsy	0.000	0.998	0.002
I24.8 Other forms of acute ischaemic heart disease	0.002	0.998	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.000	0.998	0.002
E14 Unspecified diabetes mellitus	0.000	0.998	0.002
I82.8 Embolism and thrombosis of other specified veins	0.002	0.998	0.000
G40 Epilepsy	0.000	0.998	0.002
M89.84 Other specified disorders of bone (Hand)	0.002	0.998	0.000
S12.11 Fracture of second cervical vertebra (open)	0.001	0.998	0.000
G83.4 Cauda equina syndrome	0.000	0.998	0.002
H16.8 Other keratitis	0.002	0.998	0.000
H16.4 Corneal neovascularisation	0.002	0.998	0.000
H16.3 Interstitial and deep keratitis	0.002	0.998	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.002	0.998	0.000
H49.8 Other paralytic strabismus	0.002	0.998	0.000
H49.4 Progressive external ophthalmoplegia	0.002	0.998	0.000
H49.3 Total (external) ophthalmoplegia	0.002	0.998	0.000
J01.0 Acute maxillary sinusitis	0.000	0.998	0.002
T93.2 Sequelae of other fractures of lower limb	0.002	0.998	0.000
Y44.2 Anticoagulants	0.002	0.998	0.000
Z01.4 Gynaecological examination (general)(routine)	0.002	0.998	0.000
C75.8 Pluriglandular involvement, unspecified	0.000	0.998	0.001
C75.5 Aortic body and other paraganglia	0.000	0.998	0.001
C75.4 Carotid body	0.000	0.998	0.001
C75.3 Pineal gland	0.000	0.998	0.001
C75.2 Craniopharyngeal duct	0.000	0.998	0.001
C75.1 Pituitary gland	0.000	0.998	0.001
C75.0 Parathyroid gland	0.000	0.998	0.001
M89.09 Algoneurodystrophy (Site unspecified)	0.002	0.998	0.000
D39.1 Ovary	0.002	0.998	0.000
D39.0 Uterus	0.002	0.998	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.002	0.998	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.998	0.001
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.998	0.001
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.998	0.001
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.998	0.001
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.998	0.001
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.998	0.001
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.998	0.001
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.998	0.001
E14.8 With unspecified complications	0.000	0.998	0.002
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.002	0.998	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
S10 Superficial injury of neck	0.000	0.998	0.002
M24.16 Other articular cartilage disorders (Lower leg)	0.002	0.998	0.000
M89.08 Algoneurodystrophy (Other)	0.001	0.998	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.001	0.998	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations