TreeWAS – Variant ID: rs10860964

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Q23.1 Congenital insufficiency of aortic valve	0.043	0.957	0.000
Q23 Congenital malformations of aortic and mitral valves	0.032	0.968	0.000
Q23.0 Congenital stenosis of aortic valve	0.031	0.969	0.000
F33.9 Recurrent depressive disorder, unspecified	0.000	0.970	0.030
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.023	0.976	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.023	0.976	0.000
Q23.4 Hypoplastic left heart syndrome	0.023	0.976	0.000
Q23.2 Congenital mitral stenosis	0.023	0.976	0.000
F33 Recurrent depressive disorder	0.000	0.977	0.023
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.977	0.023
Q23.3 Congenital mitral insufficiency	0.022	0.977	0.000
I31.3 Pericardial effusion (noninflammatory)	0.000	0.978	0.022
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.979	0.021
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.983	0.017
F33.8 Other recurrent depressive disorders	0.000	0.984	0.016
F45.8 Other somatoform disorders	0.000	0.985	0.015
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.986	0.014
A41.5 Septicaemia due to other Gram-negative organisms	0.000	0.988	0.012
I61.9 Intracerebral haemorrhage, unspecified	0.011	0.989	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.989	0.011
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.989	0.011
T42.4 Benzodiazepines	0.000	0.989	0.011
F45 Somatoform disorders	0.000	0.990	0.010
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.990	0.010
Z95.2 Presence of prosthetic heart valve	0.009	0.991	0.000
T42.0 Hydantoin derivatives	0.000	0.991	0.009
Z03.3 Observation for suspected nervous system disorder	0.009	0.991	0.000
J35.0 Chronic tonsillitis	0.008	0.992	0.000
F45.2 Hypochondriacal disorder	0.000	0.992	0.008
F45.0 Somatisation disorder	0.000	0.992	0.007
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.992	0.007
F45.9 Somatoform disorder, unspecified	0.000	0.993	0.007
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.993	0.007
F45.1 Undifferentiated somatoform disorder	0.000	0.993	0.007
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.993	0.007
T42.2 Succinimides and oxazolidinediones	0.000	0.993	0.007
F45.3 Somatoform autonomic dysfunction	0.000	0.993	0.007
U81.0 Vancomycin resistant agent	0.007	0.993	0.000
F45.4 Persistent somatoform pain disorder	0.000	0.993	0.007
T42.3 Barbiturates	0.000	0.993	0.006
Q20-Q28 Congenital malformations of the circulatory system	0.006	0.994	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.000	0.994	0.006
E10.3 With ophthalmic complications	0.006	0.994	0.000
E10.4 With neurological complications	0.005	0.995	0.000
T42.1 Iminostilbenes	0.000	0.995	0.005
F43 Reaction to severe stress, and adjustment disorders	0.000	0.995	0.005
F40-F48 Neurotic, stress-related and somatoform disorders	0.000	0.995	0.005
F42.9 Obsessive-compulsive disorder, unspecified	0.000	0.995	0.005
F42 Obsessive-compulsive disorder	0.000	0.995	0.005
S64.4 Injury of digital nerve of other finger	0.005	0.995	0.000
E10.1 With ketoacidosis	0.005	0.995	0.000
F43.9 Reaction to severe stress, unspecified	0.000	0.995	0.005
Q24 Other congenital malformations of heart	0.005	0.995	0.000
F48 Other neurotic disorders	0.000	0.995	0.005
I31 Other diseases of pericardium	0.000	0.995	0.005
C18.4 Transverse colon	0.000	0.995	0.005
F43.0 Acute stress reaction	0.000	0.995	0.005
Q22 Congenital malformations of pulmonary and tricuspid valves	0.005	0.995	0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.005	0.995	0.000
K62.9 Disease of anus and rectum, unspecified	0.000	0.995	0.005
Q21.0 Ventricular septal defect	0.000	0.995	0.004
Q26 Congenital malformations of great veins	0.004	0.995	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.004	0.995	0.000
C18.1 Appendix	0.000	0.995	0.005
F43.1 Posttraumatic stress disorder	0.000	0.995	0.004
Q24.8 Other specified congenital malformations of heart	0.004	0.995	0.000
Q25 Congenital malformations of great arteries	0.004	0.995	0.000
E10 Insulin-dependent diabetes mellitus	0.004	0.996	0.000
F48.9 Neurotic disorder, unspecified	0.000	0.996	0.004
F48.0 Neurasthenia	0.000	0.996	0.004
W06.0 Home	0.000	0.996	0.004
Q24.0 Dextrocardia	0.004	0.996	0.000
Q24.4 Congenital subaortic stenosis	0.004	0.996	0.000
F42.0 Predominantly obsessional thoughts or ruminations	0.000	0.996	0.004
F43.8 Other reactions to severe stress	0.000	0.996	0.004
C71.0 Cerebrum, except lobes and ventricles	0.004	0.996	0.000
F42.8 Other obsessive-compulsive disorders	0.000	0.996	0.004
F42.2 Mixed obsessional thoughts and acts	0.000	0.996	0.004
F42.1 Predominantly compulsive acts [obsessional rituals]	0.000	0.996	0.004
M43.02 Spondylolysis (Cervical region)	0.000	0.996	0.004
I31.1 Chronic constrictive pericarditis	0.000	0.996	0.004
Q24.6 Congenital heart block	0.004	0.996	0.000
Q24.3 Pulmonary infundibular stenosis	0.004	0.996	0.000
Q24.2 Cor triatriatum	0.004	0.996	0.000
Q24.1 Levocardia	0.004	0.996	0.000
Q28 Other congenital malformations of circulatory system	0.004	0.996	0.000
C18.6 Descending colon	0.000	0.996	0.004
Q22.1 Congenital pulmonary valve stenosis	0.004	0.996	0.000
I31.0 Chronic adhesive pericarditis	0.000	0.996	0.004
F48.8 Other specified neurotic disorders	0.000	0.996	0.004
F48.1 Depersonalisation-derealisation syndrome	0.000	0.996	0.004
I31.8 Other specified diseases of pericardium	0.000	0.996	0.004
I31.2 Haemopericardium, not elsewhere classified	0.000	0.996	0.004
C71.2 Temporal lobe	0.004	0.996	0.000
C71 Malignant neoplasm of brain	0.004	0.996	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.004	0.996	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.004	0.996	0.000
Q22.6 Hypoplastic right heart syndrome	0.004	0.996	0.000
Q22.5 Ebstein's anomaly	0.004	0.996	0.000
Q22.4 Congenital tricuspid stenosis	0.004	0.996	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.004	0.996	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.004	0.996	0.000
Q22.0 Pulmonary valve atresia	0.004	0.996	0.000
Q24.5 Malformation of coronary vessels	0.004	0.996	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.004	0.996	0.000
A41 Other septicaemia	0.000	0.996	0.004
Q25.4 Other congenital malformations of aorta	0.003	0.996	0.000
Q25.3 Stenosis of aorta	0.003	0.996	0.000
W07.0 Home	0.000	0.996	0.004
F44 Dissociative [conversion] disorders	0.000	0.996	0.004
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.003	0.996	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.003	0.996	0.000
Q20.6 Isomerism of atrial appendages	0.003	0.996	0.000
Q20.5 Discordant atrioventricular connexion	0.003	0.996	0.000
Q20.4 Double inlet ventricle	0.003	0.996	0.000
Q20.3 Discordant ventriculoarterial connexion	0.003	0.996	0.000
Q20.2 Double outlet left ventricle	0.003	0.996	0.000
Q20.1 Double outlet right ventricle	0.003	0.996	0.000
Q20.0 Common arterial trunk	0.003	0.996	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.003	0.996	0.000
Q26.8 Other congenital malformations of great veins	0.003	0.996	0.000
Q26.6 Portal vein-hepatic artery fistula	0.003	0.996	0.000
Q26.5 Anomalous portal venous connexion	0.003	0.996	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.003	0.996	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.003	0.996	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.003	0.996	0.000
Q26.1 Persistent left superior vena cava	0.003	0.996	0.000
Q26.0 Congenital stenosis of vena cava	0.003	0.996	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.003	0.996	0.000
Q25.6 Stenosis of pulmonary artery	0.003	0.996	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.003	0.996	0.000
Q25.8 Other congenital malformations of great arteries	0.003	0.996	0.000
Q25.5 Atresia of pulmonary artery	0.003	0.996	0.000
Q25.2 Atresia of aorta	0.003	0.996	0.000
E10.7 With multiple complications	0.003	0.997	0.000
H40.2 Primary angle-closure glaucoma	0.003	0.997	0.000
E10.8 With unspecified complications	0.003	0.997	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.003	0.997	0.000
E10.6 With other specified complications	0.003	0.997	0.000
S01.2 Open wound of nose	0.003	0.997	0.000
A41.2 Septicaemia due to unspecified staphylococcus	0.000	0.997	0.003
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.003	0.997	0.000
C71.7 Brain stem	0.003	0.997	0.000
U81 Agent resistant to vancomycin and related antibiotics	0.003	0.997	0.000
Q27 Other congenital malformations of peripheral vascular system	0.003	0.997	0.000
C77.2 Intra-abdominal lymph nodes	0.000	0.997	0.003
C71.4 Occipital lobe	0.003	0.997	0.000
G58.8 Other specified mononeuropathies	0.000	0.997	0.003
L85.8 Other specified epidermal thickening	0.000	0.997	0.003
Q25.1 Coarctation of aorta	0.003	0.997	0.000
C18 Malignant neoplasm of colon	0.000	0.997	0.003
Q21 Congenital malformations of cardiac septa	0.002	0.997	0.001
C18.8 Overlapping lesion of colon	0.000	0.997	0.003
E06.3 Autoimmune thyroiditis	0.000	0.997	0.003
Q28.9 Congenital malformation of circulatory system, unspecified	0.003	0.997	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.003	0.997	0.000
Q28.1 Other malformations of precerebral vessels	0.003	0.997	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.003	0.997	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.000	0.997	0.003
C71.9 Brain, unspecified	0.003	0.997	0.000
C71.8 Overlapping lesion of brain	0.003	0.997	0.000
T45.0 Antiallergic and antiemetic drugs	0.000	0.997	0.003
F30-F39 Mood [affective] disorders	0.000	0.997	0.003
B25.9 Cytomegaloviral disease, unspecified	0.003	0.997	0.000
C71.6 Cerebellum	0.003	0.997	0.000
C71.5 Cerebral ventricle	0.003	0.997	0.000
Q28.3 Other malformations of cerebral vessels	0.003	0.997	0.000
A41.3 Septicaemia due to Haemophilus influenzae	0.000	0.997	0.003
A41.8 Other specified septicaemia	0.000	0.997	0.003
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.997	0.003
A02.0 Salmonella gastro-enteritis	0.003	0.997	0.000
E10.5 With peripheral circulatory complications	0.003	0.997	0.000
Q25.0 Patent ductus arteriosus	0.003	0.997	0.000
W06.9 Unspecified place	0.000	0.997	0.003
R53 Malaise and fatigue	0.003	0.997	0.000
W06 Fall involving bed	0.000	0.997	0.003
F44.9 Dissociative [conversion] disorder, unspecified	0.000	0.997	0.003
F44.8 Other dissociative [conversion] disorders	0.000	0.997	0.003
F44.7 Mixed dissociative [conversion] disorders	0.000	0.997	0.003
F44.6 Dissociative anaesthesia and sensory loss	0.000	0.997	0.003
F44.3 Trance and possession disorders	0.000	0.997	0.003
F44.2 Dissociative stupor	0.000	0.997	0.003
F44.1 Dissociative fugue	0.000	0.997	0.003
U89.8 Agent resistant to other single specified antibiotic	0.000	0.997	0.003
A41.4 Septicaemia due to anaerobes	0.000	0.997	0.003
F44.0 Dissociative amnesia	0.000	0.997	0.003
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.997	0.003
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.997	0.003
C71.1 Frontal lobe	0.003	0.997	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.003	0.997	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.997	0.003
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.997	0.003
E10.0 With coma	0.003	0.997	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.997	0.003
F44.5 Dissociative convulsions	0.000	0.997	0.003
E10.2 With renal complications	0.003	0.997	0.000
M77.02 Medial epicondylitis (Upper arm)	0.003	0.997	0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.003	0.997	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.997	0.003
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.997	0.003
Q21.9 Congenital malformation of cardiac septum, unspecified	0.002	0.997	0.001
Q27.4 Congenital phlebectasia	0.002	0.997	0.000
Q27.2 Other congenital malformations of renal artery	0.002	0.997	0.000
Q27.1 Congenital renal artery stenosis	0.002	0.997	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.002	0.997	0.000
G58.9 Mononeuropathy, unspecified	0.000	0.997	0.003
N80.0 Endometriosis of uterus	0.003	0.997	0.000
U81.8 Agent resistant to other vancomycin-related antibiotic	0.002	0.997	0.000
F39 Unspecified mood [affective] disorder	0.000	0.997	0.003
F43.2 Adjustment disorders	0.000	0.997	0.003
Q21.3 Tetralogy of Fallot	0.002	0.997	0.001
F44.4 Dissociative motor disorders	0.000	0.997	0.002
C71.3 Parietal lobe	0.002	0.997	0.000
Q21.8 Other congenital malformations of cardiac septa	0.002	0.997	0.001
Q21.4 Aortopulmonary septal defect	0.002	0.997	0.001
Q21.2 Atrioventricular septal defect	0.002	0.997	0.001
A49.9 Bacterial infection, unspecified	0.000	0.998	0.002
F38 Other mood [affective] disorders	0.000	0.998	0.002
M87.9 Osteonecrosis, unspecified	0.000	0.998	0.002
C18.3 Hepatic flexure	0.000	0.998	0.002
G60.0 Hereditary motor and sensory neuropathy	0.000	0.998	0.002
H11.0 Pterygium	0.002	0.998	0.000
A41.1 Septicaemia due to other specified staphylococcus	0.000	0.998	0.002
Q27.3 Peripheral arteriovenous malformation	0.002	0.998	0.000
T39.0 Salicylates	0.000	0.998	0.002
T43.2 Other and unspecified antidepressants	0.000	0.998	0.002
W06.1 Residential institution	0.000	0.998	0.002
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
S64 Injury of nerves at wrist and hand level	0.002	0.998	0.000
T43.9 Psychotropic drug, unspecified	0.000	0.998	0.002
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
W06.2 School, other institution and public administrative area	0.000	0.998	0.002
W06.8 Other specified place	0.000	0.998	0.002
W06.7 Farm	0.000	0.998	0.002
W06.6 Industrial and construction area	0.000	0.998	0.002
W06.5 Trade and service area	0.000	0.998	0.002
W06.4 Street and highway	0.000	0.998	0.002
W06.3 Sports and athletics area	0.000	0.998	0.002
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.998	0.002
T87.6 Other and unspecified complications of amputation stump	0.000	0.998	0.002
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.998	0.002
T45.8 Other primarily systemic and haematological agents	0.000	0.998	0.002
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.998	0.002
T45.6 Fibrinolysis-affecting drugs	0.000	0.998	0.002
T45.4 Iron and its compounds	0.000	0.998	0.002
T45.3 Enzymes, not elsewhere classified	0.000	0.998	0.002
Q27.8 Other specified congenital malformations of peripheral vascular system	0.002	0.998	0.000
F30 Manic episode	0.000	0.998	0.002
L40.0 Psoriasis vulgaris	0.002	0.998	0.000
T40.2 Other opioids	0.000	0.998	0.002
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.000	0.998	0.002
T36 Poisoning by systemic antibiotics	0.000	0.998	0.002
T45.2 Vitamins, not elsewhere classified	0.000	0.998	0.002
K22.4 Dyskinesia of oesophagus	0.000	0.998	0.002
W29.9 Unspecified place	0.002	0.998	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.998	0.002
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.998	0.002
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.998	0.002
G60.8 Other hereditary and idiopathic neuropathies	0.000	0.998	0.002
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.002	0.998	0.000
A02 Other Salmonella infections	0.002	0.998	0.000
S64.3 Injury of digital nerve of thumb	0.002	0.998	0.000
G58 Other mononeuropathies	0.000	0.998	0.002
T43.6 Psychostimulants with abuse potential	0.000	0.998	0.002
W18.3 Sports and athletics area	0.000	0.998	0.002
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.998	0.002
A02.1 Salmonella septicaemia	0.002	0.998	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.002	0.998	0.000
F34 Persistent mood [affective] disorders	0.000	0.998	0.002
T36.0 Penicillins	0.000	0.998	0.002
B25 Cytomegaloviral disease	0.002	0.998	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.998	0.002
F38.8 Other specified mood [affective] disorders	0.000	0.998	0.002
F38.1 Other recurrent mood [affective] disorders	0.000	0.998	0.002
F38.0 Other single mood [affective] disorders	0.000	0.998	0.002
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.000	0.998	0.002
M87.94 Osteonecrosis, unspecified (Hand)	0.000	0.998	0.002
M87.93 Osteonecrosis, unspecified (Forearm)	0.000	0.998	0.002
M87.92 Osteonecrosis, unspecified (Upper arm)	0.000	0.998	0.002
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.000	0.998	0.002
C70.0 Cerebral meninges	0.002	0.998	0.000
K27.3 Acute without haemorrhage or perforation	0.002	0.998	0.000
B25.8 Other cytomegaloviral diseases	0.002	0.998	0.000
K27 Peptic ulcer, site unspecified	0.002	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.998	0.002
K27.7 Chronic without haemorrhage or perforation	0.002	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.998	0.002
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.998	0.002
E10.9 Without complications	0.002	0.998	0.000
N02.9 Unspecified	0.000	0.998	0.002
S64.9 Injury of unspecified nerve at wrist and hand level	0.002	0.998	0.000
S64.8 Injury of other nerves at wrist and hand level	0.002	0.998	0.000
C70 Malignant neoplasm of meninges	0.002	0.998	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.002	0.998	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.000	0.998	0.002
W06.28 Fall involving bed; School, other institution and public administrative area; While engaged in other specified activities	0.000	0.998	0.002
Y83.0 Surgical operation with transplant of whole organ	0.002	0.998	0.000
F30.0 Hypomania	0.000	0.998	0.002
S64.2 Injury of radial nerve at wrist and hand level	0.002	0.998	0.000
T45.5 Anticoagulants	0.000	0.998	0.002
M87.98 Osteonecrosis, unspecified (Other)	0.000	0.998	0.002
X62.9 Unspecified place	0.000	0.998	0.002
F30.8 Other manic episodes	0.000	0.998	0.002
R63.1 Polydipsia	0.002	0.998	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.002	0.998	0.000
A02.9 Salmonella infection, unspecified	0.002	0.998	0.000
T36.9 Systemic antibiotic, unspecified	0.000	0.998	0.002
T36.8 Other systemic antibiotics	0.000	0.998	0.002
T36.7 Antifungal antibiotics, systemically used	0.000	0.998	0.002
T36.6 Rifamycins	0.000	0.998	0.002
T36.5 Aminoglycosides	0.000	0.998	0.002
T36.2 Chloramphenicol group	0.000	0.998	0.002
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.998	0.002
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.998	0.002
Z92.6 Personal history of chemotherapy for neoplastic disease	0.000	0.998	0.002
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.998	0.002
B25.0 Cytomegaloviral pneumonitis	0.002	0.998	0.000
F32.1 Moderate depressive episode	0.000	0.998	0.002
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.998	0.002
M87.96 Osteonecrosis, unspecified (Lower leg)	0.000	0.998	0.002
D13.0 Oesophagus	0.000	0.998	0.002
F30.1 Mania without psychotic symptoms	0.000	0.998	0.002
T40.5 Cocaine	0.000	0.998	0.002
S64.7 Injury of multiple nerves at wrist and hand level	0.002	0.998	0.000
S91.0 Open wound of ankle	0.002	0.998	0.000
T36.4 Tetracyclines	0.000	0.998	0.002
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.998	0.002
T39.4 Antirheumatics, not elsewhere classified	0.000	0.998	0.002
T39.2 Pyrazolone derivatives	0.000	0.998	0.002
T41.5 Therapeutic gases	0.000	0.998	0.002
T41.4 Anaesthetic, unspecified	0.000	0.998	0.002
T41.3 Local anaesthetics	0.000	0.998	0.002
T41.2 Other and unspecified general anaesthetics	0.000	0.998	0.002
T41.1 Intravenous anaesthetics	0.000	0.998	0.002
T41.0 Inhaled anaesthetics	0.000	0.998	0.002
T49.9 Topical agent, unspecified	0.000	0.998	0.002
T49.8 Other topical agents	0.000	0.998	0.002
T49.7 Dental drugs, topically applied	0.000	0.998	0.002
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.998	0.002
T49.5 Ophthalmological drugs and preparations	0.000	0.998	0.002
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.998	0.002
T49.3 Emollients, demulcents and protectants	0.000	0.998	0.002
T49.2 Local astringents and local detergents	0.000	0.998	0.002
T49.1 Antipruritics	0.000	0.998	0.002
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.998	0.002
A02.8 Other specified Salmonella infections	0.002	0.998	0.000
A02.2 Localised Salmonella infections	0.002	0.998	0.000
F30.9 Manic episode, unspecified	0.000	0.998	0.002
N95.8 Other specified menopausal and perimenopausal disorders	0.002	0.998	0.000
S91.3 Open wound of other parts of foot	0.002	0.998	0.000
T36.3 Macrolides	0.000	0.998	0.002
V48.4 Person injured while boarding or alighting	0.002	0.998	0.000
G60 Hereditary and idiopathic neuropathy	0.000	0.998	0.002
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.998	0.002
S64.1 Injury of median nerve at wrist and hand level	0.002	0.998	0.000
I67.8 Other specified cerebrovascular diseases	0.000	0.998	0.002
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.998	0.002
T40.8 Lysergide [LSD]	0.000	0.998	0.002
T40.7 Cannabis (derivatives)	0.000	0.998	0.002
T40.3 Methadone	0.000	0.998	0.002
T40.1 Heroin	0.000	0.998	0.002
T40.0 Opium	0.000	0.998	0.002
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.998	0.002
F34.9 Persistent mood [affective] disorder, unspecified	0.000	0.998	0.001
F34.8 Other persistent mood [affective] disorders	0.000	0.998	0.001
F34.0 Cyclothymia	0.000	0.998	0.001
B25.2 Cytomegaloviral pancreatitis	0.002	0.998	0.000
B25.1 Cytomegaloviral hepatitis	0.002	0.998	0.000
G58.0 Intercostal neuropathy	0.000	0.998	0.002
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.998	0.002
F40 Phobic anxiety disorders	0.000	0.998	0.002
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.000	0.998	0.001
C18.5 Splenic flexure	0.000	0.998	0.002
K27.6 Chronic or unspecified with both haemorrhage and perforation	0.002	0.998	0.000
K27.5 Chronic or unspecified with perforation	0.002	0.998	0.000
K27.4 Chronic or unspecified with haemorrhage	0.002	0.998	0.000
K27.2 Acute with both haemorrhage and perforation	0.002	0.998	0.000
K27.1 Acute with perforation	0.002	0.998	0.000
K27.0 Acute with haemorrhage	0.002	0.998	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.998	0.001
T37.5 Antiviral drugs	0.000	0.998	0.001
T37.4 Anthelminthics	0.000	0.998	0.001
T37.3 Other antiprotozoal drugs	0.000	0.998	0.001
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.998	0.001
T37.1 Antimycobacterial drugs	0.000	0.998	0.001
T37.0 Sulphonamides	0.000	0.998	0.001
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.998	0.001
T48.4 Expectorants	0.000	0.998	0.001
T48.3 Antitussives	0.000	0.998	0.001
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.998	0.001
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.998	0.001
T48.0 Oxytocic drugs	0.000	0.998	0.001
S82.10 Fracture of upper end of tibia (closed)	0.002	0.998	0.000
N95.1 Menopausal and female climacteric states	0.002	0.998	0.000
T47.0 Histamine H(2)-receptor antagonists	0.000	0.998	0.002
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.998	0.001
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.001
C18.0 Caecum	0.000	0.998	0.002
C70.9 Meninges, unspecified	0.001	0.998	0.000
C70.1 Spinal meninges	0.001	0.998	0.000
F30.2 Mania with psychotic symptoms	0.000	0.998	0.002
F52.2 Failure of genital response	0.002	0.998	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.002	0.998	0.000
M50.3 Other cervical disk degeneration	0.000	0.998	0.002
Z89.6 Acquired absence of leg above knee	0.000	0.998	0.002
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.000	0.998	0.002
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.002
U89 Agent resistant to other and unspecified antibiotics	0.000	0.998	0.002
K61.3 Ischiorectal abscess	0.002	0.998	0.000
M50.2 Other cervical disk displacement	0.000	0.998	0.002
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.998	0.001
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.998	0.001
T47.7 Emetics	0.000	0.998	0.001
T47.6 Antidiarrhoeal drugs	0.000	0.998	0.001
T47.5 Digestants	0.000	0.998	0.001
T47.3 Saline and osmotic laxatives	0.000	0.998	0.001
T47.2 Stimulant laxatives	0.000	0.998	0.001
Y79.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
F32 Depressive episode	0.000	0.998	0.002
C69 Malignant neoplasm of eye and adnexa	0.002	0.998	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.998	0.002
G58.7 Mononeuritis multiplex	0.000	0.998	0.001
G60.3 Idiopathic progressive neuropathy	0.000	0.998	0.001
G60.2 Neuropathy in association with hereditary ataxia	0.000	0.998	0.001
G60.1 Refsum's disease	0.000	0.998	0.001
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.998	0.001
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.998	0.001
T46.7 Peripheral vasodilators	0.000	0.998	0.001
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.998	0.001
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.998	0.001
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.001	0.998	0.000
A40.0 Septicaemia due to streptococcus, group A	0.000	0.998	0.002
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.000	0.998	0.001
S27.3 Other injuries of lung	0.001	0.998	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.998	0.002
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.998	0.001
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.998	0.001
T48.5 Anti-common-cold drugs	0.000	0.998	0.001
T50.8 Diagnostic agents	0.000	0.998	0.001
F40.8 Other phobic anxiety disorders	0.000	0.998	0.001
F40.1 Social phobias	0.000	0.998	0.001
Q03.0 Malformations of aqueduct of Sylvius	0.001	0.998	0.000
S41.1 Open wound of upper arm	0.002	0.998	0.000
D13.2 Duodenum	0.000	0.998	0.002
N36.0 Urethral fistula	0.002	0.998	0.000
K35.9 Acute appendicitis, unspecified	0.000	0.998	0.002
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.998	0.001
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.998	0.001
C69.0 Conjunctiva	0.001	0.998	0.000
E89.2 Postprocedural hypoparathyroidism	0.001	0.998	0.000
T50.7 Analeptics and opioid receptor antagonists	0.000	0.998	0.001
T50.5 Appetite depressants	0.000	0.998	0.001
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.998	0.001
T50.1 Loop [high-ceiling] diuretics	0.000	0.998	0.001
T50.0 Mineralocorticoids and their antagonists	0.000	0.998	0.001
L40.8 Other psoriasis	0.001	0.999	0.000
T50.4 Drugs affecting uric acid metabolism	0.000	0.999	0.001
Z89.9 Acquired absence of limb, unspecified	0.000	0.999	0.001
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.999	0.001
F40.9 Phobic anxiety disorder, unspecified	0.000	0.999	0.001
M43.0 Spondylolysis	0.000	0.999	0.001
M77.0 Medial epicondylitis	0.001	0.999	0.000
T47.4 Other laxatives	0.000	0.999	0.001
Z89.4 Acquired absence of foot and ankle	0.000	0.999	0.001
A07.1 Giardiasis [lambliasis]	0.001	0.999	0.000
C69.2 Retina	0.001	0.999	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.000	0.999	0.001
C69.8 Overlapping lesion of eye and adnexa	0.001	0.999	0.000
C69.5 Lachrymal gland and duct	0.001	0.999	0.000
C69.4 Ciliary body	0.001	0.999	0.000
C69.1 Cornea	0.001	0.999	0.000
Z89.2 Acquired absence of upper limb above wrist	0.000	0.999	0.001
C72.9 Central nervous system, unspecified	0.001	0.999	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.001	0.999	0.000
C72.5 Other and unspecified cranial nerves	0.001	0.999	0.000
C72.4 Acoustic nerve	0.001	0.999	0.000
C72.3 Optic nerve	0.001	0.999	0.000
C72.2 Olfactory nerve	0.001	0.999	0.000
C72.1 Cauda equina	0.001	0.999	0.000
Q15.0 Congenital glaucoma	0.001	0.999	0.000
U89.9 Agent resistant to unspecified antibiotic	0.000	0.999	0.001
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.001	0.999	0.000
S42.10 Fracture of scapula (closed)	0.001	0.999	0.000
E03.8 Other specified hypothyroidism	0.001	0.999	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.999	0.001
F34.1 Dysthymia	0.000	0.999	0.001
T40.6 Other and unspecified narcotics	0.000	0.999	0.001
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.999	0.001
I35.0 Aortic (valve) stenosis	0.001	0.999	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.999	0.001
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.999	0.001
Z89 Acquired absence of limb	0.000	0.999	0.001
C18.2 Ascending colon	0.000	0.999	0.001
H43.3 Other vitreous opacities	0.000	0.999	0.001
T75.4 Effects of electric current	0.001	0.999	0.000
J35 Chronic diseases of tonsils and adenoids	0.001	0.999	0.000
C69.3 Choroid	0.001	0.999	0.000
M87 Osteonecrosis	0.000	0.999	0.001
S91 Open wound of ankle and foot	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations