TreeWAS – Variant ID: rs10894294

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E21.0 Primary hyperparathyroidism	0.000	0.621	0.379
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.624	0.376
E21.3 Hyperparathyroidism, unspecified	0.000	0.628	0.372
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.677	0.323
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.681	0.319
E21.4 Other specified disorders of parathyroid gland	0.000	0.710	0.289
E21.2 Other hyperparathyroidism	0.000	0.744	0.256
E20-E35 Disorders of other endocrine glands	0.000	0.865	0.135
E22 Hyperfunction of pituitary gland	0.000	0.882	0.118
E22.0 Acromegaly and pituitary gigantism	0.000	0.888	0.112
E27 Other disorders of adrenal gland	0.000	0.888	0.112
E29 Testicular dysfunction	0.000	0.891	0.109
E31 Polyglandular dysfunction	0.000	0.892	0.108
E27.1 Primary adrenocortical insufficiency	0.000	0.901	0.099
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.903	0.097
E32 Diseases of thymus	0.000	0.903	0.097
E30 Disorders of puberty, not elsewhere classified	0.000	0.903	0.097
E25 Adrenogenital disorders	0.000	0.904	0.096
E20 Hypoparathyroidism	0.000	0.905	0.095
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.907	0.093
E22.1 Hyperprolactinaemia	0.000	0.908	0.092
E28 Ovarian dysfunction	0.000	0.911	0.089
E29.1 Testicular hypofunction	0.000	0.911	0.089
E31.0 Autoimmune polyglandular failure	0.000	0.911	0.088
E34 Other endocrine disorders	0.000	0.912	0.088
E22.8 Other hyperfunction of pituitary gland	0.000	0.915	0.085
E26 Hyperaldosteronism	0.000	0.918	0.082
E29.9 Testicular dysfunction, unspecified	0.000	0.919	0.081
E27.5 Adrenomedullary hyperfunction	0.000	0.920	0.080
E27.0 Other adrenocortical overactivity	0.000	0.920	0.080
E29.8 Other testicular dysfunction	0.000	0.921	0.078
E29.0 Testicular hyperfunction	0.000	0.921	0.078
E31.9 Polyglandular dysfunction, unspecified	0.000	0.922	0.077
E31.8 Other polyglandular dysfunction	0.000	0.922	0.077
E31.1 Polyglandular hyperfunction	0.000	0.922	0.077
E27.8 Other specified disorders of adrenal gland	0.000	0.923	0.077
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.924	0.076
E24 Cushing's syndrome	0.000	0.925	0.075
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.926	0.073
E20.9 Hypoparathyroidism, unspecified	0.000	0.928	0.072
E27.2 Addisonian crisis	0.000	0.928	0.071
E34.9 Endocrine disorder, unspecified	0.000	0.929	0.071
E27.9 Disorder of adrenal gland, unspecified	0.000	0.930	0.070
E30.9 Disorder of puberty, unspecified	0.000	0.930	0.069
E30.8 Other disorders of puberty	0.000	0.930	0.069
E30.1 Precocious puberty	0.000	0.930	0.069
E30.0 Delayed puberty	0.000	0.930	0.069
E32.9 Disease of thymus, unspecified	0.000	0.930	0.069
E32.8 Other diseases of thymus	0.000	0.930	0.069
E32.1 Abscess of thymus	0.000	0.930	0.069
E32.0 Persistent hyperplasia of thymus	0.000	0.930	0.069
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.930	0.069
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.930	0.069
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.930	0.069
E25.9 Adrenogenital disorder, unspecified	0.000	0.931	0.069
E25.8 Other adrenogenital disorders	0.000	0.931	0.069
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.931	0.069
E20.8 Other hypoparathyroidism	0.000	0.931	0.068
E20.0 Idiopathic hypoparathyroidism	0.000	0.931	0.068
E34.3 Short stature, not elsewhere classified	0.000	0.932	0.068
E28.9 Ovarian dysfunction, unspecified	0.000	0.936	0.064
E28.8 Other ovarian dysfunction	0.000	0.936	0.064
E28.1 Androgen excess	0.000	0.936	0.064
E28.0 Oestrogen excess	0.000	0.936	0.064
E34.5 Androgen resistance syndrome	0.000	0.937	0.063
E34.4 Constitutional tall stature	0.000	0.937	0.063
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.937	0.063
E34.1 Other hypersecretion of intestinal hormones	0.000	0.937	0.063
E20.1 Pseudohypoparathyroidism	0.000	0.937	0.062
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.938	0.062
E28.2 Polycystic ovarian syndrome	0.000	0.938	0.061
E28.3 Primary ovarian failure	0.000	0.940	0.060
E26.8 Other hyperaldosteronism	0.000	0.941	0.059
E26.1 Secondary hyperaldosteronism	0.000	0.941	0.059
E34.0 Carcinoid syndrome	0.000	0.941	0.059
E26.9 Hyperaldosteronism, unspecified	0.000	0.941	0.059
E24.2 Drug-induced Cushing's syndrome	0.000	0.944	0.056
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.946	0.054
E24.3 Ectopic ACTH syndrome	0.000	0.946	0.054
E24.1 Nelson's syndrome	0.000	0.946	0.054
E24.8 Other Cushing's syndrome	0.000	0.948	0.052
E24.0 Pituitary-dependent Cushing's disease	0.000	0.948	0.051
E26.0 Primary hyperaldosteronism	0.000	0.955	0.045
G57.6 Lesion of plantar nerve	0.000	0.957	0.043
E24.9 Cushing's syndrome, unspecified	0.000	0.961	0.039
E34.8 Other specified endocrine disorders	0.001	0.961	0.038
Z88.7 Personal history of allergy to serum and vaccine	0.000	0.975	0.025
Z88.1 Personal history of allergy to other antibiotic agents	0.000	0.977	0.023
N60.2 Fibroadenosis of breast	0.000	0.979	0.021
E23 Hypofunction and other disorders of pituitary gland	0.002	0.980	0.019
Z80.4 Family history of malignant neoplasm of genital organs	0.020	0.980	0.000
N60 Benign mammary dysplasia	0.000	0.982	0.018
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.000	0.983	0.017
G57 Mononeuropathies of lower limb	0.000	0.983	0.017
N60.4 Mammary duct ectasia	0.000	0.983	0.017
N60.0 Solitary cyst of breast	0.000	0.983	0.017
Z88.5 Personal history of allergy to narcotic agent	0.000	0.983	0.017
Z88.3 Personal history of allergy to other anti-infective agents	0.000	0.984	0.016
G57.1 Meralgia paraesthetica	0.000	0.984	0.016
E23.1 Drug-induced hypopituitarism	0.001	0.985	0.013
N60.8 Other benign mammary dysplasias	0.000	0.985	0.015
G57.8 Other mononeuropathies of lower limb	0.000	0.986	0.014
M20.1 Hallux valgus (acquired)	0.000	0.986	0.014
E23.2 Diabetes insipidus	0.001	0.987	0.012
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.987	0.013
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.001	0.987	0.012
G57.0 Lesion of sciatic nerve	0.000	0.987	0.013
G57.4 Lesion of medial popliteal nerve	0.000	0.987	0.012
G57.2 Lesion of femoral nerve	0.000	0.987	0.012
N60.9 Benign mammary dysplasia, unspecified	0.000	0.988	0.012
Y95 Nosocomial condition	0.012	0.988	0.000
N60.3 Fibrosclerosis of breast	0.000	0.988	0.012
Z88.2 Personal history of allergy to sulphonamides	0.000	0.988	0.012
E23.6 Other disorders of pituitary gland	0.002	0.989	0.010
G57.9 Mononeuropathy of lower limb, unspecified	0.000	0.989	0.011
Z88.4 Personal history of allergy to anaesthetic agent	0.000	0.989	0.011
E23.7 Disorder of pituitary gland, unspecified	0.002	0.990	0.009
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.010	0.990	0.000
S63.5 Sprain and strain of wrist	0.010	0.990	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.010	0.990	0.000
F20.9 Schizophrenia, unspecified	0.000	0.990	0.010
S63.2 Multiple dislocations of fingers	0.009	0.991	0.000
G57.3 Lesion of lateral popliteal nerve	0.000	0.991	0.009
G57.5 Tarsal tunnel syndrome	0.000	0.992	0.008
S00.8 Superficial injury of other parts of head	0.008	0.992	0.000
S63.0 Dislocation of wrist	0.008	0.992	0.000
S92.00 Fracture of calcaneus (closed)	0.000	0.992	0.008
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.008	0.992	0.000
S60-S69 Injuries to the wrist and hand	0.008	0.992	0.000
S60 Superficial injury of wrist and hand	0.008	0.992	0.000
S60.2 Contusion of other parts of wrist and hand	0.008	0.992	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.008	0.992	0.000
S63.1 Dislocation finger	0.007	0.992	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.007	0.992	0.000
Y91 Evidence of alcohol involvement determined by level of intoxication	0.007	0.992	0.000
S63.6 Sprain and strain of finger(s)	0.007	0.992	0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.000	0.993	0.007
Y91.9 Alcohol involvement, not otherwise specified	0.007	0.993	0.000
Z88.6 Personal history of allergy to analgesic agent	0.000	0.993	0.007
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.007	0.993	0.000
S62 Fracture at wrist and hand level	0.007	0.993	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.007	0.993	0.000
G12.2 Motor neuron disease	0.000	0.993	0.007
S62.8 Fracture of other and unspecified parts of wrist and hand	0.007	0.993	0.000
F17.2 Dependence syndrome	0.007	0.993	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.007	0.993	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.007	0.993	0.000
S62.3 Fracture of other metacarpal bone	0.007	0.993	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.007	0.993	0.000
S67 Crushing injury of wrist and hand	0.007	0.993	0.000
F20 Schizophrenia	0.000	0.993	0.007
S65 Injury of blood vessels at wrist and hand level	0.006	0.994	0.000
N60.1 Diffuse cystic mastopathy	0.000	0.994	0.006
S62.30 Fracture of other metacarpal bone (closed)	0.006	0.994	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.006	0.994	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.006	0.994	0.000
Y98 Lifestyle-related condition	0.006	0.994	0.000
Y97 Environmental-pollution-related condition	0.006	0.994	0.000
Y96 Work-related condition	0.006	0.994	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.006	0.994	0.000
S64 Injury of nerves at wrist and hand level	0.006	0.994	0.000
S65.0 Injury of ulnar artery at wrist and hand level	0.006	0.994	0.000
Y84.6 Urinary catheterisation	0.006	0.994	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.006	0.994	0.000
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.005	0.994	0.000
Y91.3 Very severe alcohol intoxication	0.006	0.994	0.000
Y91.2 Severe alcohol intoxication	0.006	0.994	0.000
Y91.1 Moderate alcohol intoxication	0.006	0.994	0.000
Y91.0 Mild alcohol intoxication	0.006	0.994	0.000
S60.0 Contusion of finger(s) without damage to nail	0.006	0.994	0.000
G43.1 Migraine with aura [classical migraine]	0.000	0.994	0.006
F23.9 Acute and transient psychotic disorder, unspecified	0.000	0.994	0.006
F25.9 Schizoaffective disorder, unspecified	0.000	0.994	0.006
S65.4 Injury of blood vessel(s) of thumb	0.005	0.994	0.000
S62.2 Fracture of first metacarpal bone	0.005	0.994	0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.005	0.994	0.000
S62.31 Fracture of other metacarpal bone (open)	0.005	0.995	0.000
S60.1 Contusion of finger(s) with damage to nail	0.005	0.995	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.005	0.995	0.000
S62.1 Fracture of other carpal bone(s)	0.005	0.995	0.000
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.005	0.995	0.000
F25 Schizoaffective disorders	0.000	0.995	0.005
F20.8 Other schizophrenia	0.000	0.995	0.005
S62.6 Fracture of other finger	0.005	0.995	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.005	0.995	0.000
F23 Acute and transient psychotic disorders	0.000	0.995	0.005
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.005	0.995	0.000
S62.61 Fracture of other finger (open)	0.005	0.995	0.000
F20.6 Simple schizophrenia	0.000	0.995	0.005
F20.4 Postschizophrenic depression	0.000	0.995	0.005
F20.3 Undifferentiated schizophrenia	0.000	0.995	0.005
F20.1 Hebephrenic schizophrenia	0.000	0.995	0.005
S62.5 Fracture of thumb	0.005	0.995	0.000
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.005	0.995	0.000
F20.0 Paranoid schizophrenia	0.000	0.995	0.005
S64.0 Injury of ulnar nerve at wrist and hand level	0.005	0.995	0.000
R35 Polyuria	0.000	0.995	0.005
S62.4 Multiple fractures of metacarpal bones	0.005	0.995	0.000
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.005	0.995	0.000
S65.8 Injury of other blood vessels at wrist and hand level	0.005	0.995	0.000
S65.7 Injury of multiple blood vessels at wrist and hand level	0.005	0.995	0.000
S65.3 Injury of deep palmar arch	0.005	0.995	0.000
S65.2 Injury of superficial palmar arch	0.005	0.995	0.000
B91 Sequelae of poliomyelitis	0.000	0.995	0.005
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.000	0.995	0.005
S69 Other and unspecified injuries of wrist and hand	0.005	0.995	0.000
Q38.7 Pharyngeal pouch	0.000	0.995	0.005
F20.2 Catatonic schizophrenia	0.000	0.995	0.005
S62.0 Fracture of navicular [scaphoid] bone of hand	0.005	0.995	0.000
L91.0 Keloid scar	0.005	0.995	0.000
S65.5 Injury of blood vessel(s) of other finger	0.005	0.995	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.005	0.995	0.000
S68 Traumatic amputation of wrist and hand	0.005	0.995	0.000
F20.5 Residual schizophrenia	0.000	0.995	0.004
E23.0 Hypopituitarism	0.002	0.995	0.002
S64.7 Injury of multiple nerves at wrist and hand level	0.004	0.996	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.000	0.996	0.004
S64.9 Injury of unspecified nerve at wrist and hand level	0.004	0.996	0.000
S64.8 Injury of other nerves at wrist and hand level	0.004	0.996	0.000
S62.7 Multiple fractures of fingers	0.004	0.996	0.000
S92.0 Fracture of calcaneus	0.000	0.996	0.004
S62.20 Fracture of first metacarpal bone (closed)	0.004	0.996	0.000
S62.21 Fracture of first metacarpal bone (open)	0.004	0.996	0.000
Y90.9 Presence of alcohol in blood, level not specified	0.004	0.996	0.000
Y90.7 Blood alcohol level of 200-239 mg/100 ml	0.004	0.996	0.000
Y90.5 Blood alcohol level of 100-119 mg/100 ml	0.004	0.996	0.000
Y90.4 Blood alcohol level of 80-99 mg/100 ml	0.004	0.996	0.000
Y90.3 Blood alcohol level of 60-79 mg/100 ml	0.004	0.996	0.000
Y90.2 Blood alcohol level of 40-59 mg/100 ml	0.004	0.996	0.000
Y90.1 Blood alcohol level of 20-39 mg/100 ml	0.004	0.996	0.000
Y90.0 Blood alcohol level of less than 20 mg/100 ml	0.004	0.996	0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.000	0.996	0.004
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.004	0.996	0.000
F25.2 Schizoaffective disorder, mixed type	0.000	0.996	0.004
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.004	0.996	0.000
S62.11 Fracture of other carpal bone(s) (open)	0.004	0.996	0.000
S62.51 Fracture of thumb (open)	0.004	0.996	0.000
F25.0 Schizoaffective disorder, manic type	0.000	0.996	0.004
G12 Spinal muscular atrophy and related syndromes	0.000	0.996	0.004
F25.1 Schizoaffective disorder, depressive type	0.000	0.996	0.004
F25.8 Other schizoaffective disorders	0.000	0.996	0.004
Y57.9 Drug or medicament, unspecified	0.004	0.996	0.000
Y90.8 Blood alcohol level of 240 mg/100 ml or more	0.004	0.996	0.000
D13.1 Stomach	0.000	0.996	0.004
S64.4 Injury of digital nerve of other finger	0.004	0.996	0.000
S62.10 Fracture of other carpal bone(s) (closed)	0.004	0.996	0.000
Y90.6 Blood alcohol level of 120-199 mg/100 ml	0.004	0.996	0.000
F23.8 Other acute and transient psychotic disorders	0.000	0.996	0.004
F23.3 Other acute predominantly delusional psychotic disorders	0.000	0.996	0.004
F23.2 Acute schizophrenia-like psychotic disorder	0.000	0.996	0.004
S64.3 Injury of digital nerve of thumb	0.004	0.996	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.004	0.996	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.004	0.996	0.000
M75.3 Calcific tendinitis of shoulder	0.000	0.996	0.004
S62.41 Multiple fractures of metacarpal bones (open)	0.004	0.996	0.000
F28 Other nonorganic psychotic disorders	0.000	0.996	0.004
F24 Induced delusional disorder	0.000	0.996	0.004
F21 Schizotypal disorder	0.000	0.996	0.004
S64.1 Injury of median nerve at wrist and hand level	0.004	0.996	0.000
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.003	0.996	0.000
S65.1 Injury of radial artery at wrist and hand level	0.003	0.996	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.004	0.996	0.000
S60.8 Other superficial injuries of wrist and hand	0.004	0.996	0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.003	0.996	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.003	0.996	0.000
S68.4 Traumatic amputation of hand at wrist level	0.003	0.996	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.003	0.996	0.000
S69.8 Other specified injuries of wrist and hand	0.003	0.996	0.000
S92.01 Fracture of calcaneus (open)	0.000	0.996	0.003
S69.7 Multiple injuries of wrist and hand	0.003	0.997	0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.000	0.997	0.003
H40.2 Primary angle-closure glaucoma	0.003	0.997	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.997	0.003
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.997	0.003
F22 Persistent delusional disorders	0.000	0.997	0.003
S02.50 Fracture of tooth (closed)	0.000	0.997	0.003
S62.40 Multiple fractures of metacarpal bones (closed)	0.003	0.997	0.000
S42.20 Fracture of upper end of humerus (closed)	0.003	0.997	0.000
G12.9 Spinal muscular atrophy, unspecified	0.000	0.997	0.003
G12.8 Other spinal muscular atrophies and related syndromes	0.000	0.997	0.003
G12.1 Other inherited spinal muscular atrophy	0.000	0.997	0.003
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]	0.000	0.997	0.003
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.003	0.997	0.000
S69.9 Unspecified injury of wrist and hand	0.003	0.997	0.000
M62.8 Other specified disorders of muscle	0.000	0.997	0.003
Z94.8 Other transplanted organ and tissue status	0.003	0.997	0.000
S62.70 Multiple fractures of fingers (closed)	0.003	0.997	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.003	0.997	0.000
Y57 Other and unspecified drugs and medicaments	0.003	0.997	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.003	0.997	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.000	0.997	0.003
S62.50 Fracture of thumb (closed)	0.003	0.997	0.000
Q21.1 Atrial septal defect	0.000	0.997	0.003
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.997	0.003
C50.1 Central portion of breast	0.000	0.997	0.003
S62.71 Multiple fractures of fingers (open)	0.002	0.997	0.000
Y57.5 X-ray contrast media	0.003	0.997	0.000
F22.8 Other persistent delusional disorders	0.000	0.997	0.003
I42.9 Cardiomyopathy, unspecified	0.000	0.997	0.003
Y57.6 Other diagnostic agents	0.003	0.997	0.000
M67.8 Other specified disorders of synovium and tendon	0.003	0.997	0.000
M62.84 Other specified disorders of muscle (Hand)	0.000	0.997	0.003
S22.40 Multiple fractures of ribs (closed)	0.000	0.997	0.003
F22.9 Persistent delusional disorder, unspecified	0.000	0.997	0.003
M62.83 Other specified disorders of muscle (Forearm)	0.000	0.997	0.003
S61 Open wound of wrist and hand	0.003	0.997	0.000
M67.43 Ganglion, wrist	0.003	0.997	0.000
I99 Other and unspecified disorders of circulatory system	0.003	0.997	0.000
Z99.3 Dependence on wheelchair	0.003	0.997	0.000
G37 Other demyelinating diseases of central nervous system	0.000	0.997	0.003
I27.2 Other secondary pulmonary hypertension	0.003	0.997	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.002	0.997	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.000	0.997	0.003
I42.2 Other hypertrophic cardiomyopathy	0.000	0.997	0.003
G62.9 Polyneuropathy, unspecified	0.003	0.997	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.000	0.997	0.003
M62.88 Other specified disorders of muscle (Other)	0.000	0.997	0.002
X63.0 Home	0.003	0.997	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.000	0.997	0.002
M24.51 Contracture of joint (Shoulder region)	0.002	0.998	0.000
Y57.7 Vitamins, not elsewhere classified	0.002	0.998	0.000
Y57.4 Pharmaceutical excipients	0.002	0.998	0.000
Y57.3 Alcohol deterrents	0.002	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
Y57.1 Lipotropic drugs	0.002	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.002	0.998	0.000
N85.0 Endometrial glandular hyperplasia	0.000	0.998	0.002
R30.9 Painful micturition, unspecified	0.000	0.998	0.002
S22.1 Multiple fractures of thoracic spine	0.000	0.998	0.002
M62.82 Other specified disorders of muscle (Upper arm)	0.000	0.998	0.002
S32.40 Fracture of acetabulum (closed)	0.000	0.998	0.002
I35.0 Aortic (valve) stenosis	0.002	0.998	0.000
G61.0 Guillain-Barre syndrome	0.002	0.998	0.000
F22.0 Delusional disorder	0.000	0.998	0.002
G62.0 Drug-induced polyneuropathy	0.002	0.998	0.000
Y57.8 Other drugs and medicaments	0.002	0.998	0.000
N28.1 Cyst of kidney, acquired	0.002	0.998	0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.002	0.998	0.000
M24.54 Contracture of joint (Hand)	0.002	0.998	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.998	0.002
M67.4 Ganglion	0.002	0.998	0.000
Y49.2 Other and unspecified antidepressants	0.002	0.998	0.000
G37.5 Concentric sclerosis [Balo]	0.000	0.998	0.002
G37.4 Subacute necrotising myelitis	0.000	0.998	0.002
G37.2 Central pontine myelinolysis	0.000	0.998	0.002
G37.1 Central demyelination of corpus callosum	0.000	0.998	0.002
G37.0 Diffuse sclerosis	0.000	0.998	0.002
Z40 Prophylactic surgery	0.002	0.998	0.000
D14.0 Middle ear, nasal cavity and accessory sinuses	0.000	0.998	0.002
S22.4 Multiple fractures of ribs	0.000	0.998	0.002
M62.81 Other specified disorders of muscle (Shoulder region)	0.000	0.998	0.002
F11.2 Dependence syndrome	0.002	0.998	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.000	0.998	0.002
O61.0 Failed medical induction of labour	0.002	0.998	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.000	0.998	0.002
Y49.5 Other antipsychotics and neuroleptics	0.002	0.998	0.000
Y52.1 Calcium-channel blockers	0.002	0.998	0.000
Z40.8 Other prophylactic surgery	0.002	0.998	0.000
M24.5 Contracture of joint	0.002	0.998	0.000
X60-X84 Intentional self-harm	0.002	0.998	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.002	0.998	0.000
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
I27.0 Primary pulmonary hypertension	0.002	0.998	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.002	0.998	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.002	0.998	0.000
M67 Other disorders of synovium and tendon	0.002	0.998	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.002	0.998	0.000
S42.2 Fracture of upper end of humerus	0.002	0.998	0.000
X64.2 School, other institution and public administrative area	0.002	0.998	0.000
X65 Intentional self-poisoning by and exposure to alcohol	0.002	0.998	0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.002	0.998	0.000
I97.0 Postcardiotomy syndrome	0.002	0.998	0.000
W51.9 Unspecified place	0.002	0.998	0.000
X63.9 Unspecified place	0.002	0.998	0.000
X63.8 Other specified place	0.002	0.998	0.000
X63.7 Farm	0.002	0.998	0.000
X63.6 Industrial and construction area	0.002	0.998	0.000
X63.5 Trade and service area	0.002	0.998	0.000
X63.4 Street and highway	0.002	0.998	0.000
X63.3 Sports and athletics area	0.002	0.998	0.000
X63.2 School, other institution and public administrative area	0.002	0.998	0.000
X63.1 Residential institution	0.002	0.998	0.000
F29 Unspecified nonorganic psychosis	0.001	0.998	0.001
Z40.9 Prophylactic surgery, unspecified	0.002	0.998	0.000
M24.56 Contracture of joint (Lower leg)	0.002	0.998	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.002	0.998	0.000
M67.49 Ganglion, multiple sites	0.002	0.998	0.000
M67.45 Ganglion, hip	0.002	0.998	0.000
F45.8 Other somatoform disorders	0.002	0.998	0.000
X65.8 Other specified place	0.002	0.998	0.000
W22.9 Unspecified place	0.000	0.998	0.002
Y47.1 Benzodiazepines	0.000	0.998	0.002
Y49.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
C22.0 Liver cell carcinoma	0.002	0.998	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.002	0.998	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.000	0.998	0.002
C22.9 Liver, unspecified	0.002	0.998	0.000
M93.9 Osteochondropathy, unspecified	0.000	0.998	0.002
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.000	0.998	0.002
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.002	0.998	0.000
S02.10 Fracture of base of skull (closed)	0.002	0.998	0.000
S22.20 Fracture of sternum (closed)	0.000	0.998	0.002
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.000	0.998	0.002
V29.3 Motorcycle rider [any] injured in unspecified nontraffic accident	0.002	0.998	0.000
G62 Other polyneuropathies	0.002	0.998	0.000
W51 Striking against or bumped into by another person	0.002	0.998	0.000
S22.41 Multiple fractures of ribs (open)	0.000	0.998	0.002
S61.1 Open wound of finger(s) with damage to nail	0.002	0.998	0.000
D13.2 Duodenum	0.000	0.998	0.002
Q38.6 Other congenital malformations of mouth	0.000	0.998	0.002
X64.8 Other specified place	0.002	0.998	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
N28.0 Ischaemia and infarction of kidney	0.002	0.998	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.000	0.998	0.002
Q38.3 Other congenital malformations of tongue	0.000	0.998	0.002
Q38.2 Macroglossia	0.000	0.998	0.002
Q38.0 Congenital malformations of lips, not elsewhere classified	0.000	0.998	0.002
S02.5 Fracture of tooth	0.000	0.998	0.001
W51.4 Street and highway	0.002	0.998	0.000
M67.47 Ganglion, ankle and foot	0.002	0.998	0.000
G10 Huntington's disease	0.000	0.998	0.002
X78 Intentional self-harm by sharp object	0.002	0.998	0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours	0.002	0.998	0.000
S42.21 Fracture of upper end of humerus (open)	0.002	0.998	0.000
E13.9 Without complications	0.002	0.998	0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.000	0.998	0.002
Q38.8 Other congenital malformations of pharynx	0.000	0.998	0.002
X67.0 Home	0.002	0.998	0.000
V29 Motorcycle rider injured in other and unspecified transport accidents	0.002	0.998	0.000
X84 Intentional self-harm by unspecified means	0.002	0.998	0.000
X83 Intentional self-harm by other specified means	0.002	0.998	0.000
X82 Intentional self-harm by crashing of motor vehicle	0.002	0.998	0.000
X81 Intentional self-harm by jumping or lying before moving object	0.002	0.998	0.000
X80 Intentional self-harm by jumping from a high place	0.002	0.998	0.000
X79 Intentional self-harm by blunt object	0.002	0.998	0.000
X77 Intentional self-harm by steam, hot vapours and hot objects	0.002	0.998	0.000
X76 Intentional self-harm by smoke, fire and flames	0.002	0.998	0.000
X75 Intentional self-harm by explosive material	0.002	0.998	0.000
X74 Intentional self-harm by other and unspecified firearm discharge	0.002	0.998	0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge	0.002	0.998	0.000
X72 Intentional self-harm by handgun discharge	0.002	0.998	0.000
X71 Intentional self-harm by drowning and submersion	0.002	0.998	0.000
X70 Intentional self-harm by hanging, strangulation and suffocation	0.002	0.998	0.000
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours	0.002	0.998	0.000
M24.59 Contracture of joint (Site unspecified)	0.002	0.998	0.000
M24.58 Contracture of joint (Other)	0.002	0.998	0.000
M24.53 Contracture of joint (Forearm)	0.002	0.998	0.000
M24.52 Contracture of joint (Upper arm)	0.002	0.998	0.000
M24.50 Contracture of joint (Multiple sites)	0.002	0.998	0.000
M79.28 Neuralgia and neuritis, unspecified (Other)	0.002	0.998	0.000
X10.0 Home	0.002	0.998	0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics	0.002	0.998	0.000
S22.2 Fracture of sternum	0.000	0.998	0.002
V29.4 Driver injured in collision with other and unspecified motor vehicles in traffic accident	0.002	0.998	0.000
X62.9 Unspecified place	0.002	0.998	0.000
X64.9 Unspecified place	0.001	0.998	0.000
X64.0 Home	0.001	0.998	0.000
X64.7 Farm	0.001	0.998	0.000
X64.6 Industrial and construction area	0.001	0.998	0.000
X64.5 Trade and service area	0.001	0.998	0.000
X64.4 Street and highway	0.001	0.998	0.000
X64.3 Sports and athletics area	0.001	0.998	0.000
X64.1 Residential institution	0.001	0.998	0.000
Y49.9 Psychotropic drug, unspecified	0.002	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.002	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.002	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
Y60.4 During endoscopic examination	0.000	0.998	0.002
M67.9 Disorder of synovium and tendon, unspecified	0.002	0.998	0.000
M67.3 Transient synovitis	0.002	0.998	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.000	0.998	0.001
R72 Abnormality of white blood cells, not elsewhere classified	0.002	0.998	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.002	0.998	0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.000	0.998	0.002
W64.9 Unspecified place	0.002	0.998	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.002	0.998	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.000	0.998	0.002
M13.99 Arthritis, unspecified (Site unspecified)	0.000	0.998	0.002
I97.1 Other functional disturbances following cardiac surgery	0.002	0.998	0.000
L60.8 Other nail disorders	0.000	0.998	0.002
M67.1 Other contracture of tendon (sheath)	0.002	0.998	0.000
X65.9 Unspecified place	0.001	0.998	0.000
X65.0 Home	0.001	0.998	0.000
X65.7 Farm	0.001	0.998	0.000
X65.6 Industrial and construction area	0.001	0.998	0.000
X65.5 Trade and service area	0.001	0.998	0.000
X65.4 Street and highway	0.001	0.998	0.000
X65.3 Sports and athletics area	0.001	0.998	0.000
X65.2 School, other institution and public administrative area	0.001	0.998	0.000
X65.1 Residential institution	0.001	0.998	0.000
X78.2 School, other institution and public administrative area	0.002	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
I27 Other pulmonary heart diseases	0.002	0.998	0.000
X63.99 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system; Unspecified place ;During unspecified activity	0.001	0.998	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.000	0.998	0.002
M67.2 Synovial hypertrophy, not elsewhere classified	0.002	0.998	0.000
X10 Contact with hot drinks, food, fats and cooking oils	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations