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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10911628
log Bayes Factor = 0.322976
Chromosome 1   position 184,649,503  (GRCh37) Explore rs10911628 on Ensembl!
Variant rs10911628 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
G90-G99 Other disorders of the nervous system
0.409 0.591 0.000
Chapter VI Diseases of the nervous system
0.399 0.601 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.398 0.602 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.392 0.608 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.389 0.611 0.000
G95 Other diseases of spinal cord
0.374 0.626 0.000
G93 Other disorders of brain
0.366 0.634 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.361 0.639 0.000
G60 Hereditary and idiopathic neuropathy
0.355 0.645 0.000
G70-G73 Diseases of myoneural junction and muscle
0.347 0.653 0.000
G91 Hydrocephalus
0.342 0.658 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.339 0.661 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.334 0.666 0.000
G95.8 Other specified diseases of spinal cord
0.330 0.670 0.000
G37 Other demyelinating diseases of central nervous system
0.328 0.672 0.000
G62 Other polyneuropathies
0.323 0.677 0.000
G61 Inflammatory polyneuropathy
0.322 0.677 0.000
G95.9 Disease of spinal cord, unspecified
0.322 0.678 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.318 0.682 0.000
G60.8 Other hereditary and idiopathic neuropathies
0.310 0.690 0.000
G93.9 Disorder of brain, unspecified
0.307 0.693 0.000
G93.0 Cerebral cysts
0.305 0.695 0.000
G90 Disorders of autonomic nervous system
0.305 0.695 0.000
G30-G32 Other degenerative diseases of the nervous system
0.305 0.695 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.304 0.696 0.000
G93.3 Postviral fatigue syndrome
0.304 0.696 0.000
G12 Spinal muscular atrophy and related syndromes
0.300 0.700 0.000
G60.0 Hereditary motor and sensory neuropathy
0.299 0.701 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.293 0.707 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.293 0.707 0.000
G92 Toxic encephalopathy
0.293 0.707 0.000
G93.6 Cerebral oedema
0.290 0.710 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.286 0.714 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.286 0.714 0.000
G83 Other paralytic syndromes
0.285 0.715 0.000
G70 Myasthenia gravis and other myoneural disorders
0.284 0.716 0.000
G72 Other myopathies
0.282 0.718 0.000
G95.2 Cord compression, unspecified
0.279 0.721 0.000
G64 Other disorders of peripheral nervous system
0.279 0.721 0.000
G96 Other disorders of central nervous system
0.278 0.722 0.000
G91.9 Hydrocephalus, unspecified
0.278 0.722 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.278 0.722 0.000
G35 Multiple sclerosis
0.277 0.723 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.277 0.723 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.275 0.725 0.000
G81 Hemiplegia
0.274 0.726 0.000
G12.2 Motor neuron disease
0.272 0.728 0.000
G62.8 Other specified polyneuropathies
0.271 0.729 0.000
G91.1 Obstructive hydrocephalus
0.270 0.730 0.000
G95.0 Syringomyelia and syringobulbia
0.268 0.732 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.267 0.733 0.000
G63.2 Diabetic polyneuropathy
0.266 0.733 0.000
G93.2 Benign intracranial hypertension
0.264 0.736 0.000
G93.7 Reye's syndrome
0.263 0.737 0.000
G93.5 Compression of brain
0.263 0.737 0.000
G61.0 Guillain-Barre syndrome
0.260 0.740 0.000
G36 Other acute disseminated demyelination
0.259 0.741 0.000
G71 Primary disorders of muscles
0.258 0.741 0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified
0.254 0.745 0.000
G60.3 Idiopathic progressive neuropathy
0.254 0.745 0.000
G60.2 Neuropathy in association with hereditary ataxia
0.254 0.745 0.000
G60.1 Refsum's disease
0.254 0.745 0.000
G61.8 Other inflammatory polyneuropathies
0.253 0.747 0.000
G30 Alzheimer's disease
0.252 0.748 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.249 0.751 0.000
G91.8 Other hydrocephalus
0.245 0.754 0.000
G91.3 Posttraumatic hydrocephalus, unspecified
0.245 0.754 0.000
G91.2 Normal-pressure hydrocephalus
0.245 0.754 0.000
G91.0 Communicating hydrocephalus
0.245 0.754 0.000
T39.1 4-Aminophenol derivatives
0.245 0.755 0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.243 0.757 0.000
G14 Postpolio syndrome
0.243 0.757 0.000
G10 Huntington's disease
0.243 0.757 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.242 0.758 0.000
G90.2 Horner's syndrome
0.242 0.758 0.000
G93.4 Encephalopathy, unspecified
0.241 0.759 0.000
G62.9 Polyneuropathy, unspecified
0.240 0.760 0.000
G70.0 Myasthenia gravis
0.239 0.761 0.000
G20-G26 Extrapyramidal and movement disorders
0.237 0.763 0.000
G72.9 Myopathy, unspecified
0.236 0.764 0.000
G95.1 Vascular myelopathies
0.235 0.765 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.235 0.765 0.000
G37.5 Concentric sclerosis [Balo]
0.235 0.765 0.000
G37.4 Subacute necrotising myelitis
0.235 0.765 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.235 0.765 0.000
G37.2 Central pontine myelinolysis
0.235 0.765 0.000
G37.1 Central demyelination of corpus callosum
0.235 0.765 0.000
G37.0 Diffuse sclerosis
0.235 0.765 0.000
G11 Hereditary ataxia
0.234 0.766 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.234 0.766 0.000
G81.9 Hemiplegia, unspecified
0.232 0.768 0.000
G62.2 Polyneuropathy due to other toxic agents
0.231 0.768 0.000
G62.1 Alcoholic polyneuropathy
0.231 0.768 0.000
G62.0 Drug-induced polyneuropathy
0.231 0.768 0.000
G61.9 Inflammatory polyneuropathy, unspecified
0.231 0.769 0.000
G61.1 Serum neuropathy
0.231 0.769 0.000
G52 Disorders of other cranial nerves
0.231 0.769 0.000
G83.2 Monoplegia of upper limb
0.229 0.771 0.000
G63.8 Polyneuropathy in other diseases classified elsewhere
0.228 0.772 0.000
G63.6 Polyneuropathy in other musculoskeletal disorders
0.228 0.772 0.000
G63.5 Polyneuropathy in systemic connective tissue disorders
0.228 0.772 0.000
G63.4 Polyneuropathy in nutritional deficiency
0.228 0.772 0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.228 0.772 0.000
G63.1 Polyneuropathy in neoplastic disease
0.228 0.772 0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.228 0.772 0.000
G80 Infantile cerebral palsy
0.228 0.772 0.000
G93.8 Other specified disorders of brain
0.227 0.773 0.000
G83.4 Cauda equina syndrome
0.224 0.776 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.222 0.778 0.000
G90.8 Other disorders of autonomic nervous system
0.218 0.781 0.000
G90.4 Autonomic dysreflexia
0.218 0.781 0.000
G90.3 Multisystem degeneration
0.218 0.781 0.000
G90.1 Familial dysautonomia [Riley-Day]
0.218 0.781 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.218 0.781 0.000
G83.9 Paralytic syndrome, unspecified
0.218 0.782 0.000
G30.0 Alzheimer's disease with early onset
0.218 0.782 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.216 0.784 0.000
G12.9 Spinal muscular atrophy, unspecified
0.215 0.785 0.000
G12.8 Other spinal muscular atrophies and related syndromes
0.215 0.785 0.000
G12.1 Other inherited spinal muscular atrophy
0.215 0.785 0.000
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]
0.215 0.785 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.214 0.786 0.000
G56 Mononeuropathies of upper limb
0.213 0.787 0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere
0.210 0.789 0.000
G94.2 Hydrocephalus in other diseases classified elsewhere
0.210 0.789 0.000
G94.1 Hydrocephalus in neoplastic disease
0.210 0.789 0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere
0.210 0.789 0.000
G82 Paraplegia and tetraplegia
0.208 0.792 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.208 0.792 0.000
G83.8 Other specified paralytic syndromes
0.204 0.795 0.000
G83.5 Locked-in syndrome
0.204 0.795 0.000
G83.3 Monoplegia, unspecified
0.204 0.795 0.000
G83.1 Monoplegia of lower limb
0.204 0.795 0.000
G83.0 Diplegia of upper limbs
0.204 0.795 0.000
G70.9 Myoneural disorder, unspecified
0.204 0.796 0.000
G70.8 Other specified myoneural disorders
0.204 0.796 0.000
G70.2 Congenital and developmental myasthenia
0.204 0.796 0.000
G70.1 Toxic myoneural disorders
0.204 0.796 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.204 0.796 0.000
G72.8 Other specified myopathies
0.202 0.797 0.000
G72.4 Inflammatory myopathy, not elsewhere classified
0.202 0.797 0.000
G72.3 Periodic paralysis
0.202 0.797 0.000
G72.2 Myopathy due to other toxic agents
0.202 0.797 0.000
G72.1 Alcoholic myopathy
0.202 0.797 0.000
G72.0 Drug-induced myopathy
0.202 0.797 0.000
G96.1 Disorders of meninges, not elsewhere classified
0.202 0.798 0.000
T39.0 Salicylates
0.201 0.799 0.000
G96.9 Disorder of central nervous system, unspecified
0.199 0.800 0.000
G96.8 Other specified disorders of central nervous system
0.199 0.800 0.000
G97.9 Postprocedural disorder of nervous system, unspecified
0.199 0.801 0.000
G97.2 Intracranial hypotension following ventricular shunting
0.199 0.801 0.000
G97.0 Cerebrospinal fluid leak from spinal puncture
0.199 0.801 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.199 0.801 0.000
G00 Bacterial meningitis, not elsewhere classified
0.199 0.801 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.199 0.801 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.199 0.801 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.199 0.801 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.198 0.801 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.198 0.801 0.000
G81.1 Spastic hemiplegia
0.197 0.803 0.000
G81.0 Flaccid hemiplegia
0.197 0.803 0.000
G97.1 Other reaction to spinal and lumbar puncture
0.195 0.805 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.194 0.805 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.194 0.806 0.000
G71.1 Myotonic disorders
0.194 0.806 0.000
G03 Meningitis due to other and unspecified causes
0.193 0.807 0.000
G52.9 Cranial nerve disorder, unspecified
0.191 0.809 0.000
G52.8 Disorders of other specified cranial nerves
0.189 0.811 0.000
G50 Disorders of trigeminal nerve
0.189 0.811 0.000
G97.8 Other postprocedural disorders of nervous system
0.188 0.812 0.000
G25 Other extrapyramidal and movement disorders
0.187 0.813 0.000
G71.0 Muscular dystrophy
0.187 0.813 0.000
G36.9 Acute disseminated demyelination, unspecified
0.186 0.814 0.000
G36.8 Other specified acute disseminated demyelination
0.186 0.814 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.186 0.814 0.000
G36.0 Neuromyelitis optica [Devic]
0.186 0.814 0.000
G71.9 Primary disorder of muscle, unspecified
0.185 0.814 0.000
G71.8 Other primary disorders of muscles
0.185 0.814 0.000
G71.3 Mitochondrial myopathy, not elsewhere classified
0.185 0.814 0.000
G71.2 Congenital myopathies
0.185 0.814 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.185 0.815 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.182 0.818 0.000
G96.0 Cerebrospinal fluid leak
0.182 0.818 0.000
G30.8 Other Alzheimer's disease
0.180 0.819 0.000
G30.1 Alzheimer's disease with late onset
0.180 0.819 0.000
G54 Nerve root and plexus disorders
0.180 0.820 0.000
G58 Other mononeuropathies
0.179 0.821 0.000
G73.7 Myopathy other diseases classified elsewhere
0.178 0.821 0.000
G73.6 Myopathy in metabolic diseases
0.178 0.821 0.000
G73.5 Myopathy in endocrine diseases
0.178 0.821 0.000
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere
0.178 0.821 0.000
G73.3 Myasthenic syndromes in other diseases classified elsewhere
0.178 0.821 0.000
G73.2 Other myasthenic syndromes in neoplastic disease
0.178 0.821 0.000
G73.1 Eaton-Lambert syndrome
0.178 0.821 0.000
G73.0 Myasthenic syndromes in endocrine diseases
0.178 0.821 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.178 0.822 0.000
G57 Mononeuropathies of lower limb
0.177 0.823 0.000
G56.0 Carpal tunnel syndrome
0.177 0.823 0.000
G59.0 Diabetic mononeuropathy
0.176 0.824 0.000
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere
0.174 0.825 0.000
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema
0.174 0.825 0.000
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease
0.174 0.825 0.000
G13.0 Paraneoplastic neuromyopathy and neuropathy
0.174 0.825 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.173 0.827 0.000
G06.2 Extradural and subdural abscess, unspecified
0.173 0.827 0.000
G30.9 Alzheimer's disease, unspecified
0.172 0.828 0.000
G23 Other degenerative diseases of basal ganglia
0.170 0.830 0.000
G21 Secondary Parkinsonism
0.170 0.830 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.170 0.830 0.000
G22 Parkinsonism in diseases classified elsewhere
0.170 0.830 0.000
G11.8 Other hereditary ataxias
0.168 0.832 0.000
G11.4 Hereditary spastic paraplegia
0.168 0.832 0.000
G11.3 Cerebellar ataxia with defective DNA repair
0.168 0.832 0.000
G11.2 Late-onset cerebellar ataxia
0.168 0.832 0.000
G11.1 Early-onset cerebellar ataxia
0.168 0.832 0.000
G11.0 Congenital nonprogressive ataxia
0.168 0.832 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.168 0.832 0.000
T39.4 Antirheumatics, not elsewhere classified
0.168 0.832 0.000
T39.2 Pyrazolone derivatives
0.168 0.832 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.168 0.832 0.000
G52.7 Disorders of multiple cranial nerves
0.166 0.834 0.000
G52.3 Disorders of hypoglossal nerve
0.166 0.834 0.000
G52.2 Disorders of vagus nerve
0.166 0.834 0.000
G52.1 Disorders of glossopharyngeal nerve
0.166 0.834 0.000
G52.0 Disorders of olfactory nerve
0.166 0.834 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.165 0.835 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.164 0.836 0.000
G80.8 Other infantile cerebral palsy
0.163 0.836 0.000
G80.4 Ataxic cerebral palsy
0.163 0.836 0.000
G80.3 Dyskinetic cerebral palsy
0.163 0.836 0.000
G80.2 Infantile hemiplegia
0.163 0.836 0.000
G80.1 Spastic diplegia
0.163 0.836 0.000
G80.0 Spastic cerebral palsy
0.163 0.836 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.163 0.837 0.000
G56.2 Lesion of ulnar nerve
0.162 0.838 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.161 0.839 0.000
G82.4 Spastic tetraplegia
0.161 0.839 0.000
G56.1 Other lesions of median nerve
0.159 0.841 0.000
G11.9 Hereditary ataxia, unspecified
0.158 0.841 0.000
G24 Dystonia
0.159 0.841 0.000
G51 Facial nerve disorders
0.157 0.843 0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.157 0.843 0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.157 0.843 0.000
G06.1 Intraspinal abscess and granuloma
0.155 0.845 0.000
G06.0 Intracranial abscess and granuloma
0.155 0.845 0.000
G56.3 Lesion of radial nerve
0.155 0.845 0.000
T45.0 Antiallergic and antiemetic drugs
0.154 0.845 0.000
G59.8 Other mononeuropathies in diseases classified elsewhere
0.153 0.847 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.153 0.847 0.000
G56.4 Causalgia
0.153 0.847 0.000
G80.9 Infantile cerebral palsy, unspecified
0.151 0.848 0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.151 0.848 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.149 0.851 0.000
G31.8 Other specified degenerative diseases of nervous system
0.149 0.851 0.000
G82.3 Flaccid tetraplegia
0.149 0.851 0.000
G82.0 Flaccid paraplegia
0.149 0.851 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.149 0.851 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.149 0.851 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.149 0.851 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.149 0.851 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.149 0.851 0.000
T36 Poisoning by systemic antibiotics
0.149 0.851 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.149 0.851 0.000
G25.0 Essential tremor
0.148 0.852 0.000
G25.3 Myoclonus
0.147 0.853 0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.146 0.854 0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.146 0.854 0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.146 0.854 0.000
G82.1 Spastic paraplegia
0.143 0.856 0.000
G00.9 Bacterial meningitis, unspecified
0.143 0.857 0.000
G00.8 Other bacterial meningitis
0.143 0.857 0.000
G00.3 Staphylococcal meningitis
0.143 0.857 0.000
G00.2 Streptococcal meningitis
0.143 0.857 0.000
G00.1 Pneumococcal meningitis
0.143 0.857 0.000
G00.0 Haemophilus meningitis
0.143 0.857 0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere
0.143 0.857 0.000
G02.1 Meningitis in mycoses
0.143 0.857 0.000
G02.0 Meningitis in viral diseases classified elsewhere
0.143 0.857 0.000
G54.6 Phantom limb syndrome with pain
0.142 0.858 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.140 0.860 0.000
G57.1 Meralgia paraesthetica
0.139 0.860 0.000
G31.2 Degeneration of nervous system due to alcohol
0.139 0.861 0.000
G03.8 Meningitis due to other specified causes
0.139 0.861 0.000
G03.2 Benign recurrent meningitis [Mollaret]
0.139 0.861 0.000
G03.1 Chronic meningitis
0.139 0.861 0.000
G03.0 Nonpyogenic meningitis
0.139 0.861 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.139 0.861 0.000
G31.0 Circumscribed brain atrophy
0.138 0.862 0.000
T43.2 Other and unspecified antidepressants
0.137 0.863 0.000
G50.9 Disorder of trigeminal nerve, unspecified
0.136 0.864 0.000
G50.8 Other disorders of trigeminal nerve
0.136 0.864 0.000
G50.1 Atypical facial pain
0.136 0.864 0.000
G25.9 Extrapyramidal and movement disorder, unspecified
0.134 0.866 0.000
G25.6 Drug-induced tics and other tics of organic origin
0.134 0.866 0.000
G25.5 Other chorea
0.134 0.866 0.000
G25.4 Drug-induced chorea
0.134 0.866 0.000
G25.2 Other specified forms of tremor
0.134 0.866 0.000
G25.1 Drug-induced tremor
0.134 0.866 0.000
G03.9 Meningitis, unspecified
0.133 0.867 0.000
G50.0 Trigeminal neuralgia
0.133 0.867 0.000
T45.5 Anticoagulants
0.133 0.867 0.000
G53.8 Other cranial nerve disorders in other diseases classified elsewhere
0.133 0.867 0.000
G53.3 Multiple cranial nerve palsies in neoplastic disease
0.133 0.867 0.000
G53.2 Multiple cranial nerve palsies in sarcoidosis
0.133 0.867 0.000
G53.1 Multiple cranial nerve palsies in infectious and parasitic diseases classified elsewhere
0.133 0.867 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.132 0.868 0.000
G58.8 Other specified mononeuropathies
0.131 0.869 0.000
G82.2 Paraplegia, unspecified
0.131 0.869 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.131 0.869 0.000
T50.8 Diagnostic agents
0.131 0.869 0.000
T50.7 Analeptics and opioid receptor antagonists
0.131 0.869 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.131 0.869 0.000
T50.5 Appetite depressants
0.131 0.869 0.000
T50.4 Drugs affecting uric acid metabolism
0.131 0.869 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.131 0.869 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.131 0.869 0.000
T50.1 Loop [high-ceiling] diuretics
0.131 0.869 0.000
T50.0 Mineralocorticoids and their antagonists
0.131 0.869 0.000
T40.6 Other and unspecified narcotics
0.130 0.870 0.000
G54.8 Other nerve root and plexus disorders
0.129 0.871 0.000
G54.7 Phantom limb syndrome without pain
0.129 0.871 0.000
G54.5 Neuralgic amyotrophy
0.129 0.871 0.000
G54.4 Lumbosacral root disorders, not elsewhere classified
0.129 0.871 0.000
G54.3 Thoracic root disorders, not elsewhere classified
0.129 0.871 0.000
G54.2 Cervical root disorders, not elsewhere classified
0.129 0.871 0.000
G54.1 Lumbosacral plexus disorders
0.129 0.871 0.000
G82.5 Tetraplegia, unspecified
0.129 0.871 0.000
G58.7 Mononeuritis multiplex
0.129 0.871 0.000
G58.0 Intercostal neuropathy
0.129 0.871 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.128 0.872 0.000
T45.8 Other primarily systemic and haematological agents
0.128 0.872 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.128 0.872 0.000
T45.6 Fibrinolysis-affecting drugs
0.128 0.872 0.000
T45.4 Iron and its compounds
0.128 0.872 0.000
T45.3 Enzymes, not elsewhere classified
0.128 0.872 0.000
T45.2 Vitamins, not elsewhere classified
0.128 0.872 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.128 0.872 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.127 0.873 0.000
G57.5 Tarsal tunnel syndrome
0.127 0.873 0.000
G57.4 Lesion of medial popliteal nerve
0.127 0.873 0.000
G57.3 Lesion of lateral popliteal nerve
0.127 0.873 0.000
G57.2 Lesion of femoral nerve
0.127 0.873 0.000
G57.0 Lesion of sciatic nerve
0.127 0.873 0.000
G53.0 Postzoster neuralgia
0.126 0.874 0.000
G56.8 Other mononeuropathies of upper limb
0.125 0.875 0.000
T40.2 Other opioids
0.125 0.875 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.124 0.876 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.124 0.876 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.124 0.876 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.124 0.876 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.124 0.876 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.124 0.876 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.124 0.876 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.124 0.876 0.000
T44.0 Anticholinesterase agents
0.124 0.876 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.124 0.876 0.000
G21.9 Secondary Parkinsonism, unspecified
0.122 0.878 0.000
G21.8 Other secondary Parkinsonism
0.122 0.878 0.000
G21.4 Vascular parkinsonism
0.122 0.878 0.000
G21.3 Postencephalitic Parkinsonism
0.122 0.878 0.000
G21.2 Secondary Parkinsonism due to other external agents
0.122 0.878 0.000
G21.1 Other drug-induced secondary Parkinsonism
0.122 0.878 0.000
G21.0 Malignant neuroleptic syndrome
0.122 0.878 0.000
G23.9 Degenerative disease of basal ganglia, unspecified
0.122 0.878 0.000
G23.8 Other specified degenerative diseases of basal ganglia
0.122 0.878 0.000
G23.3 Multiple system atrophy, cerebellar type
0.122 0.878 0.000
G23.2 Striatonigral degeneration
0.122 0.878 0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
0.122 0.878 0.000
G23.0 Hallervorden-Spatz disease
0.122 0.878 0.000
T43.9 Psychotropic drug, unspecified
0.120 0.880 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.120 0.880 0.000
T43.6 Psychostimulants with abuse potential
0.120 0.880 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.120 0.880 0.000
G54.0 Brachial plexus disorders
0.119 0.881 0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.118 0.882 0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified
0.118 0.882 0.000
G04.1 Tropical spastic paraplegia
0.118 0.882 0.000
G04.0 Acute disseminated encephalitis
0.118 0.882 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.118 0.882 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.117 0.883 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.117 0.883 0.000
T40.8 Lysergide [LSD]
0.117 0.883 0.000
T40.7 Cannabis (derivatives)
0.117 0.883 0.000
T40.5 Cocaine
0.117 0.883 0.000
T40.3 Methadone
0.117 0.883 0.000
T40.1 Heroin
0.117 0.883 0.000
T40.0 Opium
0.117 0.883 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.115 0.885 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.115 0.885 0.000
G24.5 Blepharospasm
0.114 0.886 0.000
G24.8 Other dystonia
0.114 0.886 0.000
G24.4 Idiopathic orofacial dystonia
0.114 0.886 0.000
G24.3 Spasmodic torticollis
0.114 0.886 0.000
G24.2 Idiopathic nonfamilial dystonia
0.114 0.886 0.000
G24.1 Idiopathic familial dystonia
0.114 0.886 0.000
G24.0 Drug-induced dystonia
0.114 0.886 0.000
G51.3 Clonic hemifacial spasm
0.113 0.886 0.000
G58.9 Mononeuropathy, unspecified
0.113 0.887 0.000
G51.9 Disorder of facial nerve, unspecified
0.113 0.887 0.000
G51.8 Other disorders of facial nerve
0.113 0.887 0.000
G51.4 Facial myokymia
0.113 0.887 0.000
G51.2 Melkersson's syndrome
0.113 0.887 0.000
G51.1 Geniculate ganglionitis
0.113 0.887 0.000
G57.6 Lesion of plantar nerve
0.113 0.887 0.000
G57.8 Other mononeuropathies of lower limb
0.111 0.889 0.000
T40.4 Other synthetic narcotics
0.111 0.889 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.110 0.890 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.108 0.892 0.000
T38.9 Other and unspecified hormone antagonists
0.107 0.893 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.107 0.893 0.000
T38.7 Androgens and anabolic congeners
0.107 0.893 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.107 0.893 0.000
T38.5 Other oestrogens and progestogens
0.107 0.893 0.000
T38.4 Oral contraceptives
0.107 0.893 0.000
T38.2 Antithyroid drugs
0.107 0.893 0.000
T38.1 Thyroid hormones and substitutes
0.107 0.893 0.000
T38.0 Glucocorticoids and synthetic analogues
0.107 0.893 0.000
T36.9 Systemic antibiotic, unspecified
0.107 0.893 0.000
T36.8 Other systemic antibiotics
0.107 0.893 0.000
T36.7 Antifungal antibiotics, systemically used
0.107 0.893 0.000
T36.6 Rifamycins
0.107 0.893 0.000
T36.5 Aminoglycosides
0.107 0.893 0.000
T36.4 Tetracyclines
0.107 0.893 0.000
T36.3 Macrolides
0.107 0.893 0.000
T36.2 Chloramphenicol group
0.107 0.893 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.107 0.893 0.000
T36.0 Penicillins
0.107 0.893 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.107 0.893 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.107 0.893 0.000
T37.5 Antiviral drugs
0.107 0.893 0.000
T37.4 Anthelminthics
0.107 0.893 0.000
T37.3 Other antiprotozoal drugs
0.107 0.893 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.107 0.893 0.000
T37.1 Antimycobacterial drugs
0.107 0.893 0.000
T37.0 Sulphonamides
0.107 0.893 0.000
T41.5 Therapeutic gases
0.107 0.893 0.000
T41.4 Anaesthetic, unspecified
0.107 0.893 0.000
T41.3 Local anaesthetics
0.107 0.893 0.000
T41.2 Other and unspecified general anaesthetics
0.107 0.893 0.000
T41.1 Intravenous anaesthetics
0.107 0.893 0.000
T41.0 Inhaled anaesthetics
0.107 0.893 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.107 0.893 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.107 0.893 0.000
T47.7 Emetics
0.107 0.893 0.000
T47.6 Antidiarrhoeal drugs
0.107 0.893 0.000
T47.5 Digestants
0.107 0.893 0.000
T47.4 Other laxatives
0.107 0.893 0.000
T47.3 Saline and osmotic laxatives
0.107 0.893 0.000
T47.2 Stimulant laxatives
0.107 0.893 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.107 0.893 0.000
T47.0 Histamine H(2)-receptor antagonists
0.107 0.893 0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.107 0.893 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.107 0.893 0.000
T48.5 Anti-common-cold drugs
0.107 0.893 0.000
T48.4 Expectorants
0.107 0.893 0.000
T48.3 Antitussives
0.107 0.893 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.107 0.893 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.107 0.893 0.000
T48.0 Oxytocic drugs
0.107 0.893 0.000
T49.9 Topical agent, unspecified
0.107 0.893 0.000
T49.8 Other topical agents
0.107 0.893 0.000
T49.7 Dental drugs, topically applied
0.107 0.893 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.107 0.893 0.000
T49.5 Ophthalmological drugs and preparations
0.107 0.893 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.107 0.893 0.000
T49.3 Emollients, demulcents and protectants
0.107 0.893 0.000
T49.2 Local astringents and local detergents
0.107 0.893 0.000
T49.1 Antipruritics
0.107 0.893 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.107 0.893 0.000
G20 Parkinson's disease
0.104 0.896 0.000
T42.4 Benzodiazepines
0.104 0.896 0.000
T46.1 Calcium-channel blockers
0.104 0.896 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.103 0.897 0.000
G24.9 Dystonia, unspecified
0.102 0.898 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.099 0.900 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.099 0.900 0.000
T46.7 Peripheral vasodilators
0.099 0.900 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.099 0.900 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.099 0.900 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.099 0.900 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.099 0.900 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.094 0.906 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.094 0.906 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.094 0.906 0.000
T42.3 Barbiturates
0.094 0.906 0.000
T42.2 Succinimides and oxazolidinediones
0.094 0.906 0.000
T42.1 Iminostilbenes
0.094 0.906 0.000
T42.0 Hydantoin derivatives
0.094 0.906 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.092 0.907 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.092 0.908 0.000
G40-G47 Episodic and paroxysmal disorders
0.091 0.909 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.089 0.911 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.084 0.916 0.001
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.082 0.917 0.000
G51.0 Bell's palsy
0.078 0.922 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.076 0.923 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.076 0.924 0.000
G47 Sleep disorders
0.076 0.924 0.000
G41 Status epilepticus
0.069 0.931 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.065 0.935 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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