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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10919064
log Bayes Factor = 13.8908
Chromosome 1   position 169,093,398  (GRCh37) Explore rs10919064 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
D68.2 Hereditary deficiency of other clotting factors
0.000 0.000 1.000
D68 Other coagulation defects
0.000 0.000 1.000
D68.5 Primary Thrombophilia
0.000 0.003 0.997
D68.8 Other specified coagulation defects
0.000 0.015 0.985
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.000 0.024 0.976
D68.4 Acquired coagulation factor deficiency
0.000 0.197 0.803
D68.6 Other Thrombophilia
0.000 0.232 0.768
D68.1 Hereditary factor XI deficiency
0.000 0.326 0.674
D68.0 Von Willebrand's disease
0.000 0.458 0.542
D68.9 Coagulation defect, unspecified
0.000 0.481 0.519
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.503 0.497
I80 Phlebitis and thrombophlebitis
0.000 0.548 0.452
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.561 0.439
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.574 0.426
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.638 0.362
D66 Hereditary factor VIII deficiency
0.000 0.699 0.301
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.717 0.283
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.724 0.276
D67 Hereditary factor IX deficiency
0.000 0.734 0.266
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.745 0.255
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.747 0.253
R10.1 Pain localised to upper abdomen
0.147 0.853 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.128 0.872 0.000
K81.0 Acute cholecystitis
0.119 0.881 0.000
K57 Diverticular disease of intestine
0.116 0.884 0.000
K57.2 Diverticular disease of large intestine with perforation and abscess
0.107 0.893 0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.102 0.898 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.100 0.900 0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.095 0.905 0.000
K57.1 Diverticular disease of small intestine without perforation or abscess
0.092 0.908 0.000
K81 Cholecystitis
0.088 0.912 0.000
K81.1 Chronic cholecystitis
0.082 0.918 0.000
K57.0 Diverticular disease of small intestine with perforation and abscess
0.072 0.928 0.000
K81.8 Other cholecystitis
0.064 0.936 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.052 0.948 0.000
K81.9 Cholecystitis, unspecified
0.049 0.951 0.000
D69 Purpura and other haemorrhagic conditions
0.000 0.956 0.044
D69.9 Haemorrhagic condition, unspecified
0.000 0.964 0.035
D69.4 Other primary thrombocytopenia
0.000 0.964 0.035
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.033 0.967 0.000
D69.8 Other specified haemorrhagic conditions
0.000 0.968 0.032
K83 Other diseases of biliary tract
0.031 0.969 0.000
D69.1 Qualitative platelet defects
0.000 0.969 0.030
K83.1 Obstruction of bile duct
0.030 0.970 0.000
K86 Other diseases of pancreas
0.026 0.974 0.000
K83.5 Biliary cyst
0.025 0.975 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.976 0.024
K83.8 Other specified diseases of biliary tract
0.024 0.976 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.024 0.976 0.000
D69.2 Other nonthrombocytopenic purpura
0.001 0.976 0.023
K85 Acute pancreatitis
0.024 0.976 0.000
K83.2 Perforation of bile duct
0.023 0.977 0.000
K86.1 Other chronic pancreatitis
0.023 0.977 0.000
K83.3 Fistula of bile duct
0.023 0.977 0.000
K83.4 Spasm of sphincter of Oddi
0.023 0.977 0.000
K85.2 Alcohol-induced acute pancreatitis
0.022 0.978 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.022 0.978 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.021 0.979 0.000
T42.4 Benzodiazepines
0.021 0.979 0.000
K86.8 Other specified diseases of pancreas
0.021 0.979 0.000
K86.3 Pseudocyst of pancreas
0.020 0.980 0.000
D23.6 Skin of upper limb, including shoulder
0.020 0.980 0.000
K85.8 Other acute pancreatitis
0.019 0.981 0.000
K85.0 Idiopathic acute pancreatitis
0.019 0.981 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.018 0.982 0.000
K83.9 Disease of biliary tract, unspecified
0.018 0.982 0.000
D69.6 Thrombocytopenia, unspecified
0.000 0.982 0.018
D69.0 Allergic purpura
0.001 0.983 0.017
K87.1 Disorders of pancreas in diseases classified elsewhere
0.017 0.983 0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere
0.017 0.983 0.000
K85.3 Drug-induced acute pancreatitis
0.017 0.983 0.000
K80 Cholelithiasis
0.016 0.984 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.985 0.015
C34.1 Upper lobe, bronchus or lung
0.014 0.986 0.000
I25.1 Atherosclerotic heart disease
0.013 0.987 0.000
K86.9 Disease of pancreas, unspecified
0.013 0.987 0.000
D69.5 Secondary thrombocytopenia
0.001 0.987 0.012
K83.0 Cholangitis
0.012 0.988 0.000
K80.3 Calculus of bile duct with cholangitis
0.012 0.988 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.011 0.989 0.000
K80.4 Calculus of bile duct with cholecystitis
0.011 0.989 0.000
K86.2 Cyst of pancreas
0.011 0.989 0.000
D80-D89 Certain disorders involving the immune mechanism
0.000 0.989 0.011
S92.00 Fracture of calcaneus (closed)
0.010 0.990 0.000
D86 Sarcoidosis
0.000 0.990 0.010
D50-D53 Nutritional anaemias
0.000 0.990 0.010
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.010 0.990 0.000
K85.9 Acute pancreatitis, unspecified
0.009 0.991 0.000
I47.2 Ventricular tachycardia
0.009 0.991 0.000
D86.8 Sarcoidosis of other and combined sites
0.000 0.991 0.009
T42.0 Hydantoin derivatives
0.009 0.991 0.000
D84 Other immunodeficiencies
0.000 0.991 0.009
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction
0.009 0.991 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.991 0.009
D52 Folate deficiency anaemia
0.000 0.992 0.008
I25.5 Ischaemic cardiomyopathy
0.008 0.992 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.008 0.992 0.000
T42.3 Barbiturates
0.008 0.992 0.000
T42.2 Succinimides and oxazolidinediones
0.008 0.992 0.000
D86.3 Sarcoidosis of skin
0.000 0.992 0.008
D86.1 Sarcoidosis of lymph nodes
0.000 0.992 0.008
T42.1 Iminostilbenes
0.008 0.992 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.008 0.992 0.000
D51 Vitamin B12 deficiency anaemia
0.000 0.992 0.008
D81 Combined immunodeficiencies
0.000 0.992 0.008
D55-D59 Haemolytic anaemias
0.000 0.992 0.008
D84.1 Defects in the complement system
0.000 0.992 0.008
D83 Common variable immunodeficiency
0.000 0.992 0.008
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.992 0.008
I25 Chronic ischaemic heart disease
0.008 0.992 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.008 0.992 0.000
K80.8 Other cholelithiasis
0.008 0.992 0.000
D52.9 Folate deficiency anaemia, unspecified
0.000 0.992 0.008
D82 Immunodeficiency associated with other major defects
0.000 0.993 0.007
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.007 0.993 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.007 0.993 0.000
T39.1 4-Aminophenol derivatives
0.007 0.993 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.007 0.993 0.000
D84.9 Immunodeficiency, unspecified
0.000 0.993 0.007
D53 Other nutritional anaemias
0.000 0.993 0.007
M81.9 Osteoporosis, unspecified
0.007 0.993 0.000
I47 Paroxysmal tachycardia
0.007 0.993 0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.993 0.007
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.007 0.993 0.000
D60-D64 Aplastic and other anaemias
0.000 0.993 0.007
I25.0 Atherosclerotic cardiovascular disease, so described
0.006 0.994 0.000
S92.0 Fracture of calcaneus
0.006 0.994 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.006 0.994 0.000
D80 Immunodeficiency with predominantly antibody defects
0.000 0.994 0.006
D52.8 Other folate deficiency anaemias
0.000 0.994 0.006
D52.1 Drug-induced folate deficiency anaemia
0.000 0.994 0.006
D52.0 Dietary folate deficiency anaemia
0.000 0.994 0.006
I25.6 Silent myocardial ischaemia
0.006 0.994 0.000
I47.1 Supraventricular tachycardia
0.006 0.994 0.000
T36 Poisoning by systemic antibiotics
0.006 0.994 0.000
D75.2 Essential thrombocytosis
0.006 0.994 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.006 0.994 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.006 0.994 0.000
I25.4 Coronary artery aneurysm
0.006 0.994 0.000
O82.1 Delivery by emergency Caesarean section
0.000 0.994 0.006
D84.8 Other specified immunodeficiencies
0.000 0.994 0.006
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.994 0.006
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.994 0.006
D51.2 Transcobalamin II deficiency
0.000 0.994 0.006
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.994 0.006
D81.9 Combined immunodeficiency, unspecified
0.000 0.994 0.006
D81.8 Other combined immunodeficiencies
0.000 0.994 0.006
D81.7 Major histocompatibility complex class II deficiency
0.000 0.994 0.006
D81.6 Major histocompatibility complex class I deficiency
0.000 0.994 0.006
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.994 0.006
D81.4 Nezelof's syndrome
0.000 0.994 0.006
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.994 0.006
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.994 0.006
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.994 0.006
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.994 0.006
D55 Anaemia due to enzyme disorders
0.000 0.994 0.006
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.006 0.994 0.000
L60.0 Ingrowing nail
0.006 0.994 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.006 0.994 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.994 0.006
D57 Sickle-cell disorders
0.000 0.994 0.006
D83.8 Other common variable immunodeficiencies
0.000 0.994 0.006
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.994 0.006
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.994 0.006
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.994 0.006
I25.3 Aneurysm of heart
0.006 0.994 0.000
G25.0 Essential tremor
0.006 0.994 0.000
D61 Other aplastic anaemias
0.000 0.994 0.006
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.994 0.006
D83.9 Common variable immunodeficiency, unspecified
0.000 0.994 0.005
D58 Other hereditary haemolytic anaemias
0.000 0.994 0.006
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.006 0.994 0.000
T45.2 Vitamins, not elsewhere classified
0.005 0.994 0.000
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.994 0.005
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.994 0.005
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.994 0.005
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.994 0.005
D82.2 Immunodeficiency with short-limbed stature
0.000 0.994 0.005
D82.0 Wiskott-Aldrich syndrome
0.000 0.994 0.005
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.005 0.995 0.000
T39.4 Antirheumatics, not elsewhere classified
0.005 0.995 0.000
T39.2 Pyrazolone derivatives
0.005 0.995 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.005 0.995 0.000
D56 Thalassaemia
0.000 0.995 0.005
T41 Poisoning by anaesthetics and therapeutic gases
0.005 0.995 0.000
T36.0 Penicillins
0.005 0.995 0.000
T36.8 Other systemic antibiotics
0.005 0.995 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.005 0.995 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.005 0.995 0.000
D53.8 Other specified nutritional anaemias
0.000 0.995 0.005
D53.2 Scorbutic anaemia
0.000 0.995 0.005
D53.0 Protein deficiency anaemia
0.000 0.995 0.005
T45.1 Antineoplastic and immunosuppressive drugs
0.005 0.995 0.000
T36.4 Tetracyclines
0.005 0.995 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.005 0.995 0.000
D53.9 Nutritional anaemia, unspecified
0.000 0.995 0.005
T36.3 Macrolides
0.005 0.995 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.005 0.995 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.005 0.995 0.000
D61.0 Constitutional aplastic anaemia
0.000 0.995 0.005
T45.5 Anticoagulants
0.005 0.995 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.005 0.995 0.000
S92.01 Fracture of calcaneus (open)
0.005 0.995 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.995 0.005
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.005 0.995 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.005 0.995 0.000
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.995 0.005
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.995 0.005
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.995 0.005
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.995 0.005
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.995 0.005
T43.2 Other and unspecified antidepressants
0.005 0.995 0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.995 0.005
D61.1 Drug-induced aplastic anaemia
0.000 0.995 0.005
T36.9 Systemic antibiotic, unspecified
0.005 0.995 0.000
T36.7 Antifungal antibiotics, systemically used
0.005 0.995 0.000
T36.6 Rifamycins
0.005 0.995 0.000
T36.5 Aminoglycosides
0.005 0.995 0.000
T36.2 Chloramphenicol group
0.005 0.995 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.005 0.995 0.000
D82.1 Di George's syndrome
0.000 0.995 0.004
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.995 0.005
C34 Malignant neoplasm of bronchus and lung
0.005 0.995 0.000
K85.1 Biliary acute pancreatitis
0.004 0.995 0.001
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.995 0.005
M81.98 Osteoporosis, unspecified (Other)
0.005 0.995 0.000
D86.9 Sarcoidosis, unspecified
0.000 0.995 0.005
D86.0 Sarcoidosis of lung
0.000 0.995 0.005
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.005 0.995 0.000
C34.3 Lower lobe, bronchus or lung
0.005 0.995 0.000
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.995 0.005
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.005 0.995 0.000
D62 Acute posthaemorrhagic anaemia
0.000 0.995 0.005
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.995 0.004
D55.8 Other anaemias due to enzyme disorders
0.000 0.995 0.004
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.995 0.004
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.995 0.004
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.995 0.004
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.995 0.004
T45.9 Primarily systemic and haematological agent, unspecified
0.004 0.995 0.000
T45.8 Other primarily systemic and haematological agents
0.004 0.995 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.004 0.995 0.000
T45.6 Fibrinolysis-affecting drugs
0.004 0.995 0.000
T45.4 Iron and its compounds
0.004 0.995 0.000
T45.3 Enzymes, not elsewhere classified
0.004 0.995 0.000
D89.3 Immune reconstitution syndrome
0.000 0.995 0.004
D57.8 Other sickle-cell disorders
0.000 0.995 0.004
D57.3 Sickle-cell trait
0.000 0.995 0.004
D57.2 Double heterozygous sickling disorders
0.000 0.995 0.004
D57.0 Sickle-cell anaemia with crisis
0.000 0.995 0.004
T46.4 Angiotensin-converting-enzyme inhibitors
0.004 0.995 0.000
D58.0 Hereditary spherocytosis
0.000 0.995 0.004
D59 Acquired haemolytic anaemia
0.000 0.995 0.004
D22.4 Melanocytic naevi of scalp and neck
0.000 0.996 0.004
D57.1 Sickle-cell anaemia without crisis
0.000 0.996 0.004
D75.1 Secondary polycythaemia
0.004 0.996 0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.996 0.004
R10 Abdominal and pelvic pain
0.004 0.996 0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.996 0.004
T46 Poisoning by agents primarily affecting the cardiovascular system
0.004 0.996 0.000
D61.8 Other specified aplastic anaemias
0.000 0.996 0.004
D61.3 Idiopathic aplastic anaemia
0.000 0.996 0.004
D61.2 Aplastic anaemia due to other external agents
0.000 0.996 0.004
D75 Other diseases of blood and blood-forming organs
0.004 0.996 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.004 0.996 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.996 0.004
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.004 0.996 0.000
D58.8 Other specified hereditary haemolytic anaemias
0.000 0.996 0.004
D58.1 Hereditary elliptocytosis
0.000 0.996 0.004
D58.9 Hereditary haemolytic anaemia, unspecified
0.000 0.996 0.004
I47.0 Reentry ventricular arrhythmia
0.004 0.996 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.004 0.996 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.004 0.996 0.000
D61.9 Aplastic anaemia, unspecified
0.000 0.996 0.004
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.996 0.004
T37.8 Other specified systemic anti-infectives and antiparasitics
0.004 0.996 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.004 0.996 0.000
T49.9 Topical agent, unspecified
0.004 0.996 0.000
T49.8 Other topical agents
0.004 0.996 0.000
T49.7 Dental drugs, topically applied
0.004 0.996 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.004 0.996 0.000
T49.5 Ophthalmological drugs and preparations
0.004 0.996 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.004 0.996 0.000
T49.3 Emollients, demulcents and protectants
0.004 0.996 0.000
T49.2 Local astringents and local detergents
0.004 0.996 0.000
T49.1 Antipruritics
0.004 0.996 0.000
S02.20 Fracture of nasal bones (closed)
0.000 0.996 0.004
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.004 0.996 0.000
D89.1 Cryoglobulinaemia
0.000 0.996 0.004
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.004 0.996 0.000
T37.5 Antiviral drugs
0.004 0.996 0.000
T37.4 Anthelminthics
0.004 0.996 0.000
T37.3 Other antiprotozoal drugs
0.004 0.996 0.000
T37.1 Antimycobacterial drugs
0.004 0.996 0.000
T37.0 Sulphonamides
0.004 0.996 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.996 0.004
T47.1 Other antacids and anti-gastric-secretion drugs
0.004 0.996 0.000
D56.9 Thalassaemia, unspecified
0.000 0.996 0.004
D56.8 Other thalassaemias
0.000 0.996 0.004
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.000 0.996 0.004
D56.2 Delta-beta thalassaemia
0.000 0.996 0.004
D56.0 Alpha thalassaemia
0.000 0.996 0.004
F52.2 Failure of genital response
0.004 0.996 0.000
T41.5 Therapeutic gases
0.004 0.996 0.000
T41.4 Anaesthetic, unspecified
0.004 0.996 0.000
T41.3 Local anaesthetics
0.004 0.996 0.000
T41.2 Other and unspecified general anaesthetics
0.004 0.996 0.000
T41.1 Intravenous anaesthetics
0.004 0.996 0.000
T41.0 Inhaled anaesthetics
0.004 0.996 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.004 0.996 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.004 0.996 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.004 0.996 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.004 0.996 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.004 0.996 0.000
T44.0 Anticholinesterase agents
0.004 0.996 0.000
T48.5 Anti-common-cold drugs
0.004 0.996 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.004 0.996 0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.004 0.996 0.000
T48.4 Expectorants
0.004 0.996 0.000
T48.3 Antitussives
0.004 0.996 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.004 0.996 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.004 0.996 0.000
T48.0 Oxytocic drugs
0.004 0.996 0.000
T43.6 Psychostimulants with abuse potential
0.004 0.996 0.000
D56.3 Thalassaemia trait
0.000 0.996 0.004
D58.2 Other haemoglobinopathies
0.000 0.996 0.003
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.004 0.996 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.004 0.996 0.000
T47.7 Emetics
0.004 0.996 0.000
T47.6 Antidiarrhoeal drugs
0.004 0.996 0.000
T47.5 Digestants
0.004 0.996 0.000
T47.3 Saline and osmotic laxatives
0.004 0.996 0.000
D56.1 Beta thalassaemia
0.000 0.996 0.003
D75.8 Other specified diseases of blood and blood-forming organs
0.004 0.996 0.000
M81 Osteoporosis without pathological fracture
0.004 0.996 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.004 0.996 0.000
T47.2 Stimulant laxatives
0.003 0.996 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.003 0.996 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.004 0.996 0.000
D60.8 Other acquired pure red cell aplasias
0.000 0.996 0.003
D60.1 Transient acquired pure red cell aplasia
0.000 0.996 0.003
D60.0 Chronic acquired pure red cell aplasia
0.000 0.996 0.003
G62.8 Other specified polyneuropathies
0.000 0.996 0.004
J32.0 Chronic maxillary sinusitis
0.004 0.996 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.004 0.996 0.000
T43.9 Psychotropic drug, unspecified
0.004 0.996 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.004 0.996 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.003 0.996 0.000
C34.8 Overlapping lesion of bronchus and lung
0.003 0.996 0.000
T50.7 Analeptics and opioid receptor antagonists
0.003 0.996 0.000
T50.5 Appetite depressants
0.003 0.996 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.003 0.996 0.000
T50.1 Loop [high-ceiling] diuretics
0.003 0.996 0.000
T50.0 Mineralocorticoids and their antagonists
0.003 0.996 0.000
K63.2 Fistula of intestine
0.000 0.996 0.004
T38.5 Other oestrogens and progestogens
0.003 0.996 0.000
M81.4 Drug-induced osteoporosis
0.003 0.996 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.003 0.996 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.003 0.996 0.000
K09.2 Other cysts of jaw
0.004 0.996 0.000
T50.8 Diagnostic agents
0.003 0.996 0.000
D59.8 Other acquired haemolytic anaemias
0.000 0.996 0.003
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.996 0.003
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.996 0.003
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.996 0.003
D59.3 Haemolytic-uraemic syndrome
0.000 0.996 0.003
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.996 0.003
D75.0 Familial erythrocytosis
0.003 0.996 0.000
S92 Fracture of foot, except ankle
0.003 0.996 0.000
M81.40 Drug-induced osteoporosis (Multiple sites)
0.003 0.997 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.003 0.997 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.003 0.997 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.003 0.997 0.000
T46.7 Peripheral vasodilators
0.003 0.997 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.003 0.997 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.003 0.997 0.000
D21.2 Connective and other soft tissue of lower limb, including hip
0.000 0.997 0.003
T38.9 Other and unspecified hormone antagonists
0.003 0.997 0.000
T38.7 Androgens and anabolic congeners
0.003 0.997 0.000
T38.4 Oral contraceptives
0.003 0.997 0.000
T38.2 Antithyroid drugs
0.003 0.997 0.000
T38.0 Glucocorticoids and synthetic analogues
0.003 0.997 0.000
T47.4 Other laxatives
0.003 0.997 0.000
T47.0 Histamine H(2)-receptor antagonists
0.003 0.997 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.003 0.997 0.000
T50.4 Drugs affecting uric acid metabolism
0.003 0.997 0.000
R59.1 Generalised enlarged lymph nodes
0.000 0.997 0.003
D60.9 Acquired pure red cell aplasia, unspecified
0.000 0.997 0.003
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.997 0.003
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.997 0.003
S92.1 Fracture of talus
0.003 0.997 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.003 0.997 0.000
T51.9 Alcohol, unspecified
0.003 0.997 0.000
S92.10 Fracture of talus (closed)
0.003 0.997 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.000 0.997 0.003
Q65.8 Other congenital deformities of hip
0.003 0.997 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.003 0.997 0.000
R10.0 Acute abdomen
0.003 0.997 0.000
H46 Optic neuritis
0.000 0.997 0.003
M81.0 Postmenopausal osteoporosis
0.003 0.997 0.000
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.997 0.003
D64 Other anaemias
0.000 0.997 0.003
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.003 0.997 0.000
S92.4 Fracture of great toe
0.003 0.997 0.000
M81.8 Other osteoporosis
0.003 0.997 0.000
M81.6 Localised osteoporosis [Lequesne]
0.003 0.997 0.000
M81.5 Idiopathic osteoporosis
0.003 0.997 0.000
M81.1 Postoophorectomy osteoporosis
0.003 0.997 0.000
R52.1 Chronic intractable pain
0.003 0.997 0.000
S92.9 Fracture of foot, unspecified
0.003 0.997 0.000
S92.40 Fracture of great toe (closed)
0.003 0.997 0.000
Y83.3 Surgical operation with formation of external stoma
0.000 0.997 0.003
S92.2 Fracture of other tarsal bone(s)
0.003 0.997 0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.000 0.997 0.003
M81.48 Drug-induced osteoporosis (Other)
0.003 0.997 0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)
0.003 0.997 0.000
M81.46 Drug-induced osteoporosis (Lower leg)
0.003 0.997 0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)
0.003 0.997 0.000
M81.44 Drug-induced osteoporosis (Hand)
0.003 0.997 0.000
M81.43 Drug-induced osteoporosis (Forearm)
0.003 0.997 0.000
M81.42 Drug-induced osteoporosis (Upper arm)
0.003 0.997 0.000
M81.41 Drug-induced osteoporosis (Shoulder region)
0.003 0.997 0.000
T39.0 Salicylates
0.003 0.997 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.003 0.997 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.003 0.997 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.003 0.997 0.000
S52.60 Fracture of lower end of both ulna and radius (closed)
0.000 0.997 0.003
C34.0 Main bronchus
0.003 0.997 0.000
G96.0 Cerebrospinal fluid leak
0.003 0.997 0.000
M81.49 Drug-induced osteoporosis (Site unspecified)
0.003 0.997 0.000
T38.1 Thyroid hormones and substitutes
0.002 0.997 0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)
0.003 0.997 0.000
D59.1 Other autoimmune haemolytic anaemias
0.000 0.997 0.003
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.997 0.003
M81.2 Osteoporosis of disuse
0.003 0.997 0.000
T40.3 Methadone
0.003 0.997 0.000
C34.2 Middle lobe, bronchus or lung
0.003 0.997 0.000
K82 Other diseases of gallbladder
0.003 0.997 0.000
S92.11 Fracture of talus (open)
0.002 0.997 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.002 0.997 0.000
I82.2 Embolism and thrombosis of vena cava
0.000 0.997 0.003
T46.1 Calcium-channel blockers
0.002 0.997 0.000
T40.5 Cocaine
0.003 0.997 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.002 0.997 0.000
T40.8 Lysergide [LSD]
0.002 0.997 0.000
T40.7 Cannabis (derivatives)
0.002 0.997 0.000
T40.0 Opium
0.002 0.997 0.000
D64.8 Other specified anaemias
0.000 0.997 0.003
M81.09 Postmenopausal osteoporosis (Site unspecified)
0.002 0.997 0.000
S92.90 Fracture of foot, unspecified (closed)
0.002 0.997 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.002 0.997 0.000
M81.08 Postmenopausal osteoporosis (Other)
0.002 0.997 0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)
0.002 0.997 0.000
M81.06 Postmenopausal osteoporosis (Lower leg)
0.002 0.997 0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)
0.002 0.997 0.000
M81.04 Postmenopausal osteoporosis (Hand)
0.002 0.997 0.000
M81.03 Postmenopausal osteoporosis (Forearm)
0.002 0.997 0.000
M81.02 Postmenopausal osteoporosis (Upper arm)
0.002 0.997 0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)
0.002 0.997 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.002 0.997 0.001
T45.0 Antiallergic and antiemetic drugs
0.002 0.997 0.000
D64.4 Congenital dyserythropoietic anaemia
0.000 0.997 0.002
D64.3 Other sideroblastic anaemias
0.000 0.997 0.002
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.997 0.002
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.997 0.002
D64.0 Hereditary sideroblastic anaemia
0.000 0.997 0.002
K82.2 Perforation of gallbladder
0.002 0.997 0.000
S02.2 Fracture of nasal bones
0.000 0.997 0.002
F52 Sexual dysfunction, not caused by organic disorder or disease
0.002 0.998 0.000
S02.60 Fracture of mandible (closed)
0.000 0.998 0.002
C34.9 Bronchus or lung, unspecified
0.002 0.998 0.000
C44.0 Skin of lip
0.002 0.998 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.002 0.998 0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)
0.002 0.998 0.000
M81.18 Postoophorectomy osteoporosis (Other)
0.002 0.998 0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)
0.002 0.998 0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)
0.002 0.998 0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)
0.002 0.998 0.000
M81.14 Postoophorectomy osteoporosis (Hand)
0.002 0.998 0.000
M81.13 Postoophorectomy osteoporosis (Forearm)
0.002 0.998 0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)
0.002 0.998 0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)
0.002 0.998 0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)
0.002 0.998 0.000
M81.59 Idiopathic osteoporosis (Site unspecified)
0.002 0.998 0.000
M81.58 Idiopathic osteoporosis (Other)
0.002 0.998 0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)
0.002 0.998 0.000
M81.56 Idiopathic osteoporosis (Lower leg)
0.002 0.998 0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)
0.002 0.998 0.000
M81.54 Idiopathic osteoporosis (Hand)
0.002 0.998 0.000
M81.53 Idiopathic osteoporosis (Forearm)
0.002 0.998 0.000
M81.52 Idiopathic osteoporosis (Upper arm)
0.002 0.998 0.000
M81.51 Idiopathic osteoporosis (Shoulder region)
0.002 0.998 0.000
M81.50 Idiopathic osteoporosis (Multiple sites)
0.002 0.998 0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)
0.002 0.998 0.000
M81.68 Localized osteoporosis [Lequesne] (Other)
0.002 0.998 0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)
0.002 0.998 0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)
0.002 0.998 0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)
0.002 0.998 0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)
0.002 0.998 0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)
0.002 0.998 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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