TreeWAS – Variant ID: rs10931753

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R49.0 Dysphonia	0.098	0.902	0.000
R49 Voice disturbances	0.044	0.956	0.000
F20.0 Paranoid schizophrenia	0.000	0.957	0.043
R49.2 Hypernasality and hyponasality	0.032	0.968	0.000
F20 Schizophrenia	0.000	0.969	0.031
R49.1 Aphonia	0.029	0.971	0.000
R49.8 Other and unspecified voice disturbances	0.026	0.974	0.000
F20.8 Other schizophrenia	0.000	0.976	0.024
F20.9 Schizophrenia, unspecified	0.000	0.976	0.024
F20.5 Residual schizophrenia	0.000	0.976	0.024
R47-R49 Symptoms and signs involving speech and voice	0.023	0.977	0.000
F20.6 Simple schizophrenia	0.000	0.978	0.022
F20.4 Postschizophrenic depression	0.000	0.978	0.022
F20.3 Undifferentiated schizophrenia	0.000	0.978	0.022
F20.1 Hebephrenic schizophrenia	0.000	0.978	0.022
F20.2 Catatonic schizophrenia	0.000	0.978	0.022
N30.2 Other chronic cystitis	0.000	0.981	0.019
R47 Speech disturbances, not elsewhere classified	0.018	0.982	0.000
Y42.5 Other oestrogens and progestogens	0.000	0.983	0.017
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.017	0.983	0.000
N30.3 Trigonitis	0.000	0.983	0.017
R47.0 Dysphasia and aphasia	0.015	0.985	0.000
N30 Cystitis	0.000	0.986	0.014
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.000	0.986	0.014
R47.8 Other and unspecified speech disturbances	0.014	0.986	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.987	0.013
R48.0 Dyslexia and alexia	0.013	0.987	0.000
R48.8 Other and unspecified symbolic dysfunctions	0.013	0.987	0.000
R48.2 Apraxia	0.012	0.987	0.000
R48.1 Agnosia	0.012	0.987	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.988	0.012
E27 Other disorders of adrenal gland	0.000	0.988	0.012
K56.6 Other and unspecified intestinal obstruction	0.000	0.988	0.012
R47.1 Dysarthria and anarthria	0.012	0.988	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.989	0.011
F23 Acute and transient psychotic disorders	0.000	0.989	0.011
M48.06 Spinal stenosis (Lumbar region)	0.000	0.989	0.011
F29 Unspecified nonorganic psychosis	0.000	0.989	0.011
Y42.0 Glucocorticoids and synthetic analogs	0.000	0.989	0.011
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.989	0.011
K56.1 Intussusception	0.000	0.989	0.011
N30.8 Other cystitis	0.000	0.989	0.011
N30.0 Acute cystitis	0.000	0.989	0.011
N30.4 Irradiation cystitis	0.000	0.989	0.011
F25 Schizoaffective disorders	0.000	0.990	0.010
F28 Other nonorganic psychotic disorders	0.000	0.990	0.010
F24 Induced delusional disorder	0.000	0.990	0.010
E27.2 Addisonian crisis	0.000	0.990	0.010
Y42.7 Androgens and anabolic congeners	0.000	0.990	0.010
E27.8 Other specified disorders of adrenal gland	0.000	0.990	0.010
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.990	0.010
E27.9 Disorder of adrenal gland, unspecified	0.000	0.990	0.010
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.000	0.990	0.009
F21 Schizotypal disorder	0.000	0.990	0.009
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.000	0.991	0.009
F23.9 Acute and transient psychotic disorder, unspecified	0.000	0.991	0.009
E27.5 Adrenomedullary hyperfunction	0.000	0.991	0.009
E27.0 Other adrenocortical overactivity	0.000	0.991	0.009
S32.00 Fracture of lumbar vertebra (closed)	0.009	0.991	0.000
F25.9 Schizoaffective disorder, unspecified	0.000	0.991	0.008
F22 Persistent delusional disorders	0.000	0.991	0.008
F23.8 Other acute and transient psychotic disorders	0.000	0.992	0.008
F23.2 Acute schizophrenia-like psychotic disorder	0.000	0.992	0.008
Y42.2 Antithyroid drugs	0.000	0.992	0.008
Y42.4 Oral contraceptives	0.000	0.992	0.008
Y42.9 Other and unspecified hormone antagonists	0.000	0.992	0.008
F23.3 Other acute predominantly delusional psychotic disorders	0.000	0.992	0.008
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.000	0.992	0.008
Y42.1 Thyroid hormones and substitutes	0.000	0.992	0.008
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.992	0.008
F25.8 Other schizoaffective disorders	0.000	0.992	0.007
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.008	0.992	0.000
F25.0 Schizoaffective disorder, manic type	0.000	0.992	0.007
F25.1 Schizoaffective disorder, depressive type	0.000	0.993	0.007
F25.2 Schizoaffective disorder, mixed type	0.000	0.993	0.007
N30.9 Cystitis, unspecified	0.000	0.993	0.007
F22.8 Other persistent delusional disorders	0.000	0.994	0.006
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.006	0.994	0.000
N30.1 Interstitial cystitis (chronic)	0.000	0.994	0.006
F22.9 Persistent delusional disorder, unspecified	0.000	0.994	0.006
S32.0 Fracture of lumbar vertebra	0.006	0.994	0.000
E61.1 Iron deficiency	0.006	0.994	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.006	0.994	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.006	0.994	0.000
K56 Paralytic ileus and intestinal obstruction without hernia	0.000	0.995	0.005
D37.4 Colon	0.005	0.995	0.000
M48.0 Spinal stenosis	0.000	0.995	0.005
S62.30 Fracture of other metacarpal bone (closed)	0.005	0.995	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.995	0.005
F22.0 Delusional disorder	0.000	0.995	0.005
M48.09 Spinal stenosis (Site unspecified)	0.000	0.995	0.005
M47.96 Spondylosis, unspecified (Lumbar region)	0.000	0.995	0.005
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.005	0.995	0.000
D37.0 Lip, oral cavity and pharynx	0.005	0.995	0.000
D48.7 Other specified sites	0.005	0.995	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.005	0.995	0.000
D37.1 Stomach	0.005	0.995	0.000
Z04.8 Examination and observation for other specified reasons	0.005	0.995	0.000
S32.01 Fracture of lumbar vertebra (open)	0.004	0.995	0.000
S30.0 Contusion of lower back and pelvis	0.004	0.995	0.000
G20 Parkinson's disease	0.000	0.996	0.004
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.004	0.996	0.000
K56.0 Paralytic ileus	0.000	0.996	0.004
S32 Fracture of lumbar spine and pelvis	0.004	0.996	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.000	0.996	0.004
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.004	0.996	0.000
S30.2 Contusion of external genital organs	0.004	0.996	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.000	0.996	0.004
C34.3 Lower lobe, bronchus or lung	0.004	0.996	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.996	0.004
D48.0 Bone and articular cartilage	0.004	0.996	0.000
D37.6 Liver, gallbladder and bile ducts	0.004	0.996	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.004	0.996	0.000
T31.0 Burns involving less than 10% of body surface	0.004	0.996	0.000
S37 Injury of urinary and pelvic organs	0.004	0.996	0.000
K56.7 Ileus, unspecified	0.000	0.996	0.004
M48.03 Spinal stenosis (Cervicothoracic region)	0.000	0.996	0.004
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.000	0.996	0.004
D39.1 Ovary	0.004	0.996	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.004	0.996	0.000
M48.04 Spinal stenosis (Thoracic region)	0.000	0.996	0.004
D37.2 Small intestine	0.004	0.996	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.004	0.996	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.004	0.996	0.000
S30.1 Contusion of abdominal wall	0.004	0.996	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.004	0.996	0.000
S36 Injury of intra-abdominal organs	0.004	0.996	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.004	0.996	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.003	0.996	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.000	0.996	0.004
D37.3 Appendix	0.003	0.996	0.000
S00.8 Superficial injury of other parts of head	0.004	0.996	0.000
D37.9 Digestive organ, unspecified	0.003	0.996	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.000	0.997	0.003
D45 Polycythaemia vera	0.003	0.997	0.000
H90.5 Sensorineural hearing loss, unspecified	0.000	0.997	0.003
S37.0 Injury of kidney	0.003	0.997	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.000	0.997	0.003
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.003	0.997	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.003	0.997	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.003	0.997	0.000
K56.4 Other impaction of intestine	0.000	0.997	0.003
S37.2 Injury of bladder	0.003	0.997	0.000
S34.1 Other injury of lumbar spinal cord	0.003	0.997	0.000
S37.9 Injury of unspecified pelvic organ	0.003	0.997	0.000
S32.2 Fracture of coccyx	0.003	0.997	0.000
D44.4 Craniopharyngeal duct	0.003	0.997	0.000
K14.8 Other diseases of tongue	0.003	0.997	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.003	0.997	0.000
D44.7 Aortic body and other paraganglia	0.003	0.997	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.003	0.997	0.000
B02.9 Zoster without complication	0.000	0.997	0.003
S36.0 Injury of spleen	0.003	0.997	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.003	0.997	0.000
D44.8 Pluriglandular involvement	0.003	0.997	0.000
D48.3 Retroperitoneum	0.003	0.997	0.000
S33.1 Dislocation of lumbar vertebra	0.003	0.997	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.003	0.997	0.000
S36.1 Injury of liver or gallbladder	0.003	0.997	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.003	0.997	0.000
S37.8 Injury of other pelvic organs	0.003	0.997	0.000
S37.7 Injury of multiple pelvic organs	0.003	0.997	0.000
S37.6 Injury of uterus	0.003	0.997	0.000
S37.5 Injury of Fallopian tube	0.003	0.997	0.000
S37.4 Injury of ovary	0.003	0.997	0.000
S37.1 Injury of ureter	0.003	0.997	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.003	0.997	0.000
S34.2 Injury of nerve root of lumbar and sacral spine	0.003	0.997	0.000
S37.00 Injury of kidney (without open wound into cavity)	0.003	0.997	0.000
D48.4 Peritoneum	0.003	0.997	0.000
D44.6 Carotid body	0.003	0.997	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.003	0.997	0.000
D39.0 Uterus	0.003	0.997	0.000
D39.9 Female genital organ, unspecified	0.003	0.997	0.000
D39.2 Placenta	0.003	0.997	0.000
D42.9 Meninges, unspecified	0.003	0.997	0.000
S37.3 Injury of urethra	0.003	0.997	0.000
D41.0 Kidney	0.003	0.997	0.000
S34.8 Injury of other and unspecified nerves at abdomen, lower back and pelvis level	0.003	0.997	0.000
S34.6 Injury of peripheral nerve(s) of abdomen, lower back and pelvis	0.003	0.997	0.000
S34.5 Injury of lumbar, sacral and pelvic sympathetic nerves	0.003	0.997	0.000
S34.4 Injury of lumbosacral plexus	0.003	0.997	0.000
S34.3 Injury of cauda equina	0.003	0.997	0.000
S34.0 Concussion and oedema of lumbar spinal cord	0.003	0.997	0.000
S36.00 Injury of spleen (without open wound into cavity)	0.003	0.997	0.000
D47.1 Chronic myeloproliferative disease	0.003	0.997	0.000
K56.3 Gallstone ileus	0.000	0.997	0.003
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.003	0.997	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.000	0.997	0.003
S37.20 Injury of bladder (without open wound into cavity)	0.003	0.997	0.000
D38.0 Larynx	0.003	0.997	0.000
S32.1 Fracture of sacrum	0.003	0.997	0.000
R63.1 Polydipsia	0.003	0.997	0.000
H81.9 Disorder of vestibular function, unspecified	0.003	0.997	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.003	0.997	0.000
S32.4 Fracture of acetabulum	0.003	0.997	0.000
S33.5 Sprain and strain of lumbar spine	0.003	0.997	0.000
S36.9 Injury of unspecified intra-abdominal organ	0.003	0.997	0.000
S36.7 Injury of multiple intra-abdominal organs	0.003	0.997	0.000
S36.5 Injury of colon	0.003	0.997	0.000
S36.3 Injury of stomach	0.003	0.997	0.000
S36.2 Injury of pancreas	0.003	0.997	0.000
S37.90 Injury of unspecified pelvic organ (without open wound into cavity)	0.003	0.997	0.000
S33.7 Sprain and strain of other and unspecified parts of lumbar spine and pelvis	0.003	0.997	0.000
S33.6 Sprain and strain of sacro-iliac joint	0.003	0.997	0.000
S33.4 Traumatic rupture of symphysis pubis	0.003	0.997	0.000
S33.3 Dislocation of other and unspecified parts of lumbar spine and pelvis	0.003	0.997	0.000
S33.0 Traumatic rupture of lumbar intervertebral disk	0.003	0.997	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.003	0.997	0.000
D44.5 Pineal gland	0.003	0.997	0.000
D44.2 Parathyroid gland	0.003	0.997	0.000
S36.6 Injury of rectum	0.003	0.997	0.000
D39.7 Other female genital organs	0.003	0.997	0.000
S36.10 Injury of liver or gallbladder (without open wound into cavity)	0.003	0.997	0.000
S32.3 Fracture of ilium	0.003	0.997	0.000
S37.01 Injury of kidney (with open wound into cavity)	0.003	0.997	0.000
D38.3 Mediastinum	0.003	0.997	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.003	0.997	0.000
S36.4 Injury of small intestine	0.003	0.997	0.000
C91.4 Hairy-cell leukaemia	0.003	0.997	0.000
D42.1 Spinal meninges	0.003	0.997	0.000
D42.0 Cerebral meninges	0.003	0.997	0.000
S36.8 Injury of other intra-abdominal organs	0.003	0.997	0.000
D48.6 Breast	0.003	0.997	0.000
S33.2 Dislocation of sacro-iliac and sacrococcygeal joint	0.002	0.997	0.000
S35.9 Injury of unspecified blood vessel at abdomen, lower back and pelvis level	0.002	0.997	0.000
S35.8 Injury of other blood vessels at abdomen, lower back and pelvis level	0.002	0.997	0.000
S35.7 Injury of multiple blood vessels at abdomen, lower back and pelvis level	0.002	0.997	0.000
S35.5 Injury of iliac blood vessels	0.002	0.997	0.000
S35.4 Injury of renal blood vessels	0.002	0.997	0.000
S35.3 Injury of portal or splenic vein	0.002	0.997	0.000
S35.2 Injury of coeliac or mesenteric artery	0.002	0.997	0.000
S35.1 Injury of inferior vena cava	0.002	0.997	0.000
S35.0 Injury of abdominal aorta	0.002	0.997	0.000
S38.3 Traumatic amputation of other and unspecified parts of abdomen, lower back and pelvis	0.002	0.997	0.000
S38.2 Traumatic amputation of external genital organs	0.002	0.997	0.000
S38.1 Crushing injury of other and unspecified parts of abdomen, lower back and pelvis	0.002	0.997	0.000
S38.0 Crushing injury of external genital organs	0.002	0.997	0.000
S37.21 Injury of bladder (with open wound into cavity)	0.002	0.997	0.000
S37.91 Injury of unspecified pelvic organ (with open wound into cavity)	0.002	0.997	0.000
D44.1 Adrenal gland	0.002	0.997	0.000
S32.21 Fracture of coccyx (open)	0.002	0.997	0.000
S32.20 Fracture of coccyx (closed)	0.002	0.997	0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.002	0.997	0.000
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.002	0.997	0.000
D44.9 Endocrine gland, unspecified	0.002	0.997	0.000
D44.0 Thyroid gland	0.002	0.997	0.000
S36.01 Injury of spleen (with open wound into cavity)	0.002	0.997	0.000
D38.6 Respiratory organ, unspecified	0.002	0.997	0.000
D38.4 Thymus	0.002	0.997	0.000
D41.1 Renal pelvis	0.003	0.997	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.002	0.997	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.002	0.997	0.000
H81.1 Benign paroxysmal vertigo	0.003	0.997	0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.002	0.997	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.002	0.997	0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.002	0.997	0.000
S36.11 Injury of liver or gallbladder (with open wound into cavity)	0.002	0.997	0.000
H81 Disorders of vestibular function	0.003	0.997	0.000
M89.04 Algoneurodystrophy (Hand)	0.002	0.997	0.000
S37.11 Injury of ureter (with open wound into cavity)	0.002	0.997	0.000
S37.10 Injury of ureter (without open wound into cavity)	0.002	0.997	0.000
S37.41 Injury of ovary (with open wound into cavity)	0.002	0.997	0.000
S37.40 Injury of ovary (without open wound into cavity)	0.002	0.997	0.000
S37.51 Injury of fallopian tube (with open wound into cavity)	0.002	0.997	0.000
S37.50 Injury of fallopian tube (without open wound into cavity)	0.002	0.997	0.000
S37.61 Injury of uterus (with open wound into cavity)	0.002	0.997	0.000
S37.60 Injury of uterus (without open wound into cavity)	0.002	0.997	0.000
S37.71 Injury of multiple pelvic organs (with open wound into cavity)	0.002	0.997	0.000
S37.70 Injury of multiple pelvic organs (without open wound into cavity)	0.002	0.997	0.000
S37.81 Injury of other pelvic organs (with open wound into cavity)	0.002	0.997	0.000
S37.80 Injury of other pelvic organs (without open wound into cavity)	0.002	0.997	0.000
D38.1 Trachea, bronchus and lung	0.002	0.997	0.000
D40.1 Testis	0.002	0.997	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.002	0.997	0.000
E61 Deficiency of other nutrient elements	0.002	0.997	0.000
D43.4 Spinal cord	0.002	0.998	0.000
D38.2 Pleura	0.002	0.998	0.000
D41.9 Urinary organ, unspecified	0.002	0.998	0.000
D41.7 Other urinary organs	0.002	0.998	0.000
D41.3 Urethra	0.002	0.998	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.002	0.998	0.000
S37.31 Injury of urethra (with open wound into cavity)	0.002	0.998	0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.002	0.998	0.000
D44.3 Pituitary gland	0.002	0.998	0.000
S32.11 Fracture of sacrum (open)	0.002	0.998	0.000
D40.9 Male genital organ, unspecified	0.002	0.998	0.000
D43.1 Brain, infratentorial	0.002	0.998	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.000	0.998	0.002
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.002	0.998	0.000
S36.21 Injury of pancreas (with open wound into cavity)	0.002	0.998	0.000
S36.20 Injury of pancreas (without open wound into cavity)	0.002	0.998	0.000
S36.31 Injury of stomach (with open wound into cavity)	0.002	0.998	0.000
S36.30 Injury of stomach (without open wound into cavity)	0.002	0.998	0.000
S36.51 Injury of colon (with open wound into cavity)	0.002	0.998	0.000
S36.50 Injury of colon (without open wound into cavity)	0.002	0.998	0.000
S36.71 Injury of multiple intra-abdominal organs (with open wound into cavity)	0.002	0.998	0.000
S36.70 Injury of multiple intra-abdominal organs (without open wound into cavity)	0.002	0.998	0.000
S36.91 Injury of unspecified intra-abdominal organ (with open wound into cavity)	0.002	0.998	0.000
S36.90 Injury of unspecified intra-abdominal organ (without open wound into cavity)	0.002	0.998	0.000
D38.5 Other respiratory organs	0.002	0.998	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.002	0.998	0.000
D47.4 Osteomyelofibrosis	0.002	0.998	0.000
S32.41 Fracture of acetabulum (open)	0.002	0.998	0.000
D43.9 Central nervous system, unspecified	0.002	0.998	0.000
D43.7 Other parts of central nervous system	0.002	0.998	0.000
D43.3 Cranial nerves	0.002	0.998	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.998	0.002
S36.61 Injury of rectum (with open wound into cavity)	0.002	0.998	0.000
S37.30 Injury of urethra (without open wound into cavity)	0.002	0.998	0.000
D40.0 Prostate	0.002	0.998	0.000
Y44.2 Anticoagulants	0.002	0.998	0.000
S32.5 Fracture of pubis	0.002	0.998	0.000
S36.60 Injury of rectum (without open wound into cavity)	0.002	0.998	0.000
S32.31 Fracture of ilium (open)	0.002	0.998	0.000
S36.41 Injury of small intestine (with open wound into cavity)	0.002	0.998	0.000
H81.3 Other peripheral vertigo	0.002	0.998	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.002	0.998	0.000
S36.81 Injury of other intra-abdominal organs (with open wound into cavity)	0.002	0.998	0.000
I46.9 Cardiac arrest, unspecified	0.000	0.998	0.002
D35.0 Adrenal gland	0.000	0.998	0.002
D43.0 Brain, supratentorial	0.002	0.998	0.000
K27 Peptic ulcer, site unspecified	0.000	0.998	0.002
H81.8 Other disorders of vestibular function	0.002	0.998	0.000
H81.2 Vestibular neuronitis	0.002	0.998	0.000
M48.02 Spinal stenosis (Cervical region)	0.000	0.998	0.002
D41.2 Ureter	0.002	0.998	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.002	0.998	0.000
T31 Burns classified according to extent of body surface involved	0.002	0.998	0.000
D37.7 Other digestive organs	0.002	0.998	0.000
D40.7 Other male genital organs	0.002	0.998	0.000
H81.0 Meniere's disease	0.002	0.998	0.000
M89.0 Algoneurodystrophy	0.002	0.998	0.000
S36.40 Injury of small intestine (without open wound into cavity)	0.002	0.998	0.000
S00.7 Multiple superficial injuries of head	0.002	0.998	0.000
E61.9 Deficiency of nutrient element, unspecified	0.002	0.998	0.000
E61.8 Deficiency of other specified nutrient elements	0.002	0.998	0.000
E61.7 Deficiency of multiple nutrient elements	0.002	0.998	0.000
E61.6 Vanadium deficiency	0.002	0.998	0.000
E61.5 Molybdenum deficiency	0.002	0.998	0.000
E61.4 Chromium deficiency	0.002	0.998	0.000
E61.3 Manganese deficiency	0.002	0.998	0.000
E61.0 Copper deficiency	0.002	0.998	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.000	0.998	0.002
S36.80 Injury of other intra-abdominal organs (without open wound into cavity)	0.002	0.998	0.000
S32.10 Fracture of sacrum (closed)	0.002	0.998	0.000
H81.4 Vertigo of central origin	0.002	0.998	0.000
K27.4 Chronic or unspecified with haemorrhage	0.000	0.998	0.002
M89.07 Algoneurodystrophy (Ankle and foot)	0.002	0.998	0.000
S02.30 Fracture of orbital floor (closed)	0.002	0.998	0.000
Y43.4 Immunosuppressive agents	0.002	0.998	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.002	0.998	0.000
S31 Open wound of abdomen, lower back and pelvis	0.002	0.998	0.000
S82.50 Fracture of medial malleolus (closed)	0.000	0.998	0.002
D48.5 Skin	0.002	0.998	0.000
S62.3 Fracture of other metacarpal bone	0.002	0.998	0.000
U81.0 Vancomycin resistant agent	0.000	0.998	0.002
S32.51 Fracture of pubis (open)	0.002	0.998	0.000
N18.2 Chronic kidney disease, stage 2	0.000	0.998	0.002
T31.2 Burns involving 20-29% of body surface	0.002	0.998	0.000
K27.3 Acute without haemorrhage or perforation	0.000	0.998	0.002
M89.00 Algoneurodystrophy (Multiple sites)	0.002	0.998	0.000
S32.40 Fracture of acetabulum (closed)	0.002	0.998	0.000
M11.2 Other chondrocalcinosis	0.000	0.998	0.002
M89.09 Algoneurodystrophy (Site unspecified)	0.002	0.998	0.000
M89.03 Algoneurodystrophy (Forearm)	0.002	0.998	0.000
K27.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.998	0.002
K27.5 Chronic or unspecified with perforation	0.000	0.998	0.002
K27.2 Acute with both haemorrhage and perforation	0.000	0.998	0.002
K27.1 Acute with perforation	0.000	0.998	0.002
L60.0 Ingrowing nail	0.002	0.998	0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.002	0.998	0.000
F31 Bipolar affective disorder	0.000	0.998	0.002
D43.2 Brain, unspecified	0.002	0.998	0.000
S31.2 Open wound of penis	0.002	0.998	0.000
T31.9 Burns involving 90% or more of body surface	0.002	0.998	0.000
T31.8 Burns involving 80-89% of body surface	0.002	0.998	0.000
T31.7 Burns involving 70-79% of body surface	0.002	0.998	0.000
T31.6 Burns involving 60-69% of body surface	0.002	0.998	0.000
T31.5 Burns involving 50-59% of body surface	0.002	0.998	0.000
T31.4 Burns involving 40-49% of body surface	0.002	0.998	0.000
T31.3 Burns involving 30-39% of body surface	0.002	0.998	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.000	0.998	0.002
M89.01 Algoneurodystrophy (Shoulder region)	0.002	0.998	0.000
B35.3 Tinea pedis	0.002	0.998	0.000
C91.1 Chronic lymphocytic leukaemia	0.002	0.998	0.000
K27.7 Chronic without haemorrhage or perforation	0.000	0.998	0.002
M89.08 Algoneurodystrophy (Other)	0.002	0.998	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.002	0.998	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.002	0.998	0.000
E61.2 Magnesium deficiency	0.002	0.998	0.000
H72.0 Central perforation of tympanic membrane	0.002	0.998	0.000
K14 Diseases of tongue	0.002	0.998	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.998	0.002
G61.0 Guillain-Barre syndrome	0.000	0.998	0.002
K63.2 Fistula of intestine	0.000	0.998	0.002
R12 Heartburn	0.000	0.998	0.002
F31.8 Other bipolar affective disorders	0.000	0.998	0.002
W25.9 Unspecified place	0.000	0.998	0.002
S32.30 Fracture of ilium (closed)	0.001	0.998	0.000
C91.9 Lymphoid leukaemia, unspecified	0.002	0.998	0.000
C91 Lymphoid leukaemia	0.002	0.998	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.000	0.998	0.002
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.998	0.002
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.998	0.002
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.998	0.002
K27.0 Acute with haemorrhage	0.000	0.998	0.001
S31.5 Open wound of other and unspecified external genital organs	0.001	0.998	0.000
L12.1 Cicatricial pemphigoid	0.002	0.998	0.000
F31.7 Bipolar affective disorder, currently in remission	0.000	0.998	0.002
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.998	0.002
K14.9 Disease of tongue, unspecified	0.002	0.998	0.000
D37.5 Rectum	0.002	0.998	0.000
K14.6 Glossodynia	0.002	0.998	0.000
M11.29 Other chondrocalcinosis (Site unspecified)	0.000	0.998	0.001
M11.28 Other chondrocalcinosis (Other)	0.000	0.998	0.001
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.000	0.998	0.001
M11.24 Other chondrocalcinosis (Hand)	0.000	0.998	0.001
M11.23 Other chondrocalcinosis (Forearm)	0.000	0.998	0.001
M11.22 Other chondrocalcinosis (Upper arm)	0.000	0.998	0.001
M11.20 Other chondrocalcinosis (Multiple sites)	0.000	0.998	0.001
D47.3 Essential (haemorrhagic) thrombocythaemia	0.002	0.998	0.000
I25.3 Aneurysm of heart	0.002	0.998	0.000
T31.1 Burns involving 10-19% of body surface	0.001	0.998	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.998	0.002
S31.3 Open wound of scrotum and testes	0.001	0.998	0.000
M11.27 Other chondrocalcinosis (Ankle and foot)	0.000	0.998	0.001
M11.21 Other chondrocalcinosis (Shoulder region)	0.000	0.998	0.001
S52.80 Fracture of other parts of forearm (closed)	0.000	0.998	0.002
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.998	0.002
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.998	0.002
S31.4 Open wound of vagina and vulva	0.001	0.998	0.000
C62.1 Descended testis	0.000	0.998	0.002
K14.5 Plicated tongue	0.001	0.998	0.000
K14.4 Atrophy of tongue papillae	0.001	0.998	0.000
K14.2 Median rhomboid glossitis	0.001	0.998	0.000
N32.9 Bladder disorder, unspecified	0.000	0.998	0.002
S02.8 Fractures of other skull and facial bones	0.002	0.998	0.000
Z99.3 Dependence on wheelchair	0.000	0.998	0.002
K14.3 Hypertrophy of tongue papillae	0.001	0.998	0.000
Z35.1 Supervision of pregnancy with history of abortive outcome	0.000	0.998	0.002
L92 Granulomatous disorders of skin and subcutaneous tissue	0.002	0.998	0.000
B18.1 Chronic viral hepatitis B without delta-agent	0.000	0.998	0.002
Q76.0 Spina bifida occulta	0.000	0.998	0.002
C91.8 Mature B-cell leukaemia Burkitt-type	0.001	0.998	0.000
C91.7 Other lymphoid leukaemia	0.001	0.998	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.001	0.998	0.000
C91.3 Prolymphocytic leukaemia	0.001	0.998	0.000
C91.2 Subacute lymphocytic leukaemia	0.001	0.998	0.000
K14.0 Glossitis	0.002	0.998	0.000
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.001	0.998	0.000
L92.2 Granuloma faciale [eosinophilic granuloma of skin]	0.001	0.998	0.000
S92.30 Fracture of metatarsal bone (closed)	0.001	0.999	0.000
C71.3 Parietal lobe	0.001	0.999	0.000
D41.4 Bladder	0.001	0.999	0.000
D48.1 Connective and other soft tissue	0.001	0.999	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.001	0.999	0.000
S62.31 Fracture of other metacarpal bone (open)	0.001	0.999	0.000
C25.9 Pancreas, unspecified	0.000	0.999	0.001
K14.1 Geographic tongue	0.001	0.999	0.000
S31.1 Open wound of abdominal wall	0.001	0.999	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.999	0.001
Z86.5 Personal history of other mental and behavioural disorders	0.001	0.999	0.000
C91.0 Acute lymphoblastic leukaemia	0.001	0.999	0.000
I12.9 Hypertensive renal disease without renal failure	0.001	0.999	0.000
S02.3 Fracture of orbital floor	0.001	0.999	0.000
S31.0 Open wound of lower back and pelvis	0.001	0.999	0.000
Y44.5 Thrombolytic drugs	0.001	0.999	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.001	0.999	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.000	0.999	0.001
H90 Conductive and sensorineural hearing loss	0.000	0.999	0.001
Y44 Agents primarily affecting blood constituents	0.001	0.999	0.000
Z35 Supervision of high-risk pregnancy	0.000	0.999	0.001
E22.0 Acromegaly and pituitary gigantism	0.000	0.999	0.001
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.000	0.999	0.001
Z97.5 Presence of (intra-uterine) contraceptive device	0.001	0.999	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.999	0.001
S02.81 Fractures of other skull and facial bones (open)	0.001	0.999	0.000
E21.3 Hyperparathyroidism, unspecified	0.001	0.999	0.000
L92.1 Necrobiosis lipoidica, not elsewhere classified	0.001	0.999	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.000	0.999	0.001
L60.9 Nail disorder, unspecified	0.001	0.999	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.001	0.999	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.999	0.001
R23.8 Other and unspecified skin changes	0.001	0.999	0.000
D46 Myelodysplastic syndromes	0.001	0.999	0.000
H90.0 Conductive hearing loss, bilateral	0.000	0.999	0.001
L12.9 Pemphigoid, unspecified	0.001	0.999	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.001	0.999	0.000
C71.4 Occipital lobe	0.001	0.999	0.000
L92.0 Granuloma annulare	0.001	0.999	0.000
Y43.3 Other antineoplastic drugs	0.001	0.999	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.001	0.999	0.000
S02.31 Fracture of orbital floor (open)	0.001	0.999	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.001	0.999	0.000
Y44.7 Plasma substitutes	0.001	0.999	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.001	0.999	0.000
F32.1 Moderate depressive episode	0.000	0.999	0.001
N80.8 Other endometriosis	0.000	0.999	0.001
S00.4 Superficial injury of ear	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations