TreeWAS – Variant ID: rs10947091

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
E10.9 Without complications	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
L40 Psoriasis	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	0.000	0.000	1.000
T36-T50 Poisoning by drugs, medicaments and biological substances	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.000	1.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.000	1.000
E10-E14 Diabetes mellitus	0.000	0.000	1.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	1.000	0.000	0.000
E03 Other hypothyroidism	0.000	0.000	1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.001	0.999
E16 Other disorders of pancreatic internal secretion	0.000	0.001	0.999
E10.3 With ophthalmic complications	0.000	0.001	0.999
E16.2 Hypoglycaemia, unspecified	0.000	0.001	0.999
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.998	0.002	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.006	0.994
T39.1 4-Aminophenol derivatives	0.993	0.007	0.000
L40.0 Psoriasis vulgaris	0.992	0.008	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.991	0.009	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.987	0.013	0.000
T43.2 Other and unspecified antidepressants	0.982	0.018	0.000
E04 Other non-toxic goitre	0.000	0.021	0.979
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.978	0.022	0.000
E10.1 With ketoacidosis	0.000	0.024	0.976
E04.9 Non-toxic goitre, unspecified	0.000	0.025	0.975
E10.4 With neurological complications	0.000	0.042	0.958
E10.5 With peripheral circulatory complications	0.000	0.049	0.951
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.949	0.051	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.947	0.053	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.944	0.056	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.938	0.062	0.000
L40.1 Generalised pustular psoriasis	0.928	0.072	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.906	0.094	0.000
L40.8 Other psoriasis	0.905	0.095	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.898	0.102	0.000
E14 Unspecified diabetes mellitus	0.000	0.104	0.896
E10.8 With unspecified complications	0.000	0.110	0.890
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.882	0.118	0.000
E14.3 With ophthalmic complications	0.000	0.128	0.872
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.871	0.129	0.000
E10.0 With coma	0.000	0.136	0.864
E10.6 With other specified complications	0.000	0.136	0.864
E50-E64 Other nutritional deficiencies	0.000	0.140	0.860
T43.0 Tricyclic and tetracyclic antidepressants	0.858	0.142	0.000
E05.8 Other thyrotoxicosis	0.000	0.143	0.857
T43.6 Psychostimulants with abuse potential	0.841	0.159	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.831	0.169	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.802	0.198	0.000
T42.4 Benzodiazepines	0.799	0.201	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.799	0.201	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.203	0.797
T42.1 Iminostilbenes	0.782	0.217	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.781	0.219	0.000
T39.0 Salicylates	0.780	0.220	0.000
T45.0 Antiallergic and antiemetic drugs	0.778	0.222	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.778	0.222	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.774	0.226	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.774	0.226	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.769	0.231	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.764	0.236	0.000
E10.2 With renal complications	0.000	0.237	0.763
T50.6 Antidotes and chelating agents, not elsewhere classified	0.755	0.245	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.750	0.250	0.000
E55 Vitamin D deficiency	0.000	0.262	0.738
T45.1 Antineoplastic and immunosuppressive drugs	0.733	0.267	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.276	0.724
E05.5 Thyroid crisis or storm	0.000	0.283	0.717
E05.4 Thyrotoxicosis factitia	0.000	0.283	0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.283	0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.283	0.717
E10.7 With multiple complications	0.000	0.283	0.717
L40.4 Guttate psoriasis	0.717	0.283	0.000
L40.3 Pustulosis palmaris et plantaris	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.000	0.283	0.717
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.717	0.283	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.717	0.283	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.000	0.283	0.717
T43.9 Psychotropic drug, unspecified	0.717	0.283	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.717	0.283	0.000
E03.5 Myxoedema coma	0.000	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.000	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.000	0.283	0.717
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.283	0.717
E15 Nondiabetic hypoglycaemic coma	0.000	0.283	0.716
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.284	0.716
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.284	0.716
E16.4 Abnormal secretion of gastrin	0.000	0.284	0.716
E16.3 Increased secretion of glucagon	0.000	0.284	0.716
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.716	0.284	0.000
T39.4 Antirheumatics, not elsewhere classified	0.715	0.284	0.000
T39.2 Pyrazolone derivatives	0.715	0.284	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.710	0.289	0.000
T42.3 Barbiturates	0.710	0.289	0.000
T42.2 Succinimides and oxazolidinediones	0.710	0.289	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.708	0.292	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.708	0.292	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.708	0.292	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.708	0.292	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.708	0.292	0.000
T44.0 Anticholinesterase agents	0.708	0.292	0.000
T36 Poisoning by systemic antibiotics	0.705	0.295	0.000
E04.8 Other specified non-toxic goitre	0.000	0.298	0.702
T47.0 Histamine H(2)-receptor antagonists	0.699	0.301	0.000
E53 Deficiency of other B group vitamins	0.000	0.310	0.690
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.690	0.310	0.000
T50.8 Diagnostic agents	0.685	0.315	0.000
E04.0 Non-toxic diffuse goitre	0.000	0.317	0.683
T50.7 Analeptics and opioid receptor antagonists	0.681	0.319	0.000
T50.5 Appetite depressants	0.681	0.319	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.681	0.319	0.000
T50.1 Loop [high-ceiling] diuretics	0.681	0.319	0.000
T50.0 Mineralocorticoids and their antagonists	0.681	0.319	0.000
E06 Thyroiditis	0.000	0.334	0.666
E07 Other disorders of thyroid	0.000	0.340	0.660
T48.5 Anti-common-cold drugs	0.659	0.341	0.000
E51 Thiamine deficiency	0.000	0.350	0.650
E55.9 Vitamin D deficiency, unspecified	0.000	0.350	0.650
E14.1 With ketoacidosis	0.000	0.351	0.649
E58 Dietary calcium deficiency	0.000	0.351	0.649
E16.1 Other hypoglycaemia	0.000	0.355	0.645
T50.4 Drugs affecting uric acid metabolism	0.643	0.357	0.000
E14.7 With multiple complications	0.000	0.358	0.642
E14.6 With other specified complications	0.000	0.358	0.642
E14.2 Withrenal complications	0.000	0.358	0.642
E14.0 With coma	0.000	0.358	0.642
T47.4 Other laxatives	0.630	0.370	0.000
T46.1 Calcium-channel blockers	0.627	0.373	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.624	0.376	0.000
T45.8 Other primarily systemic and haematological agents	0.624	0.376	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.624	0.376	0.000
T45.6 Fibrinolysis-affecting drugs	0.624	0.376	0.000
T45.4 Iron and its compounds	0.624	0.376	0.000
T45.3 Enzymes, not elsewhere classified	0.624	0.376	0.000
K90 Intestinal malabsorption	0.000	0.377	0.623
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.383	0.617
E63 Other nutritional deficiencies	0.000	0.383	0.617
E56 Other vitamin deficiencies	0.000	0.383	0.617
E50 Vitamin A deficiency	0.000	0.383	0.617
E60 Dietary zinc deficiency	0.000	0.383	0.617
E59 Dietary selenium deficiency	0.000	0.383	0.617
E54 Ascorbic acid deficiency	0.000	0.383	0.617
E52 Niacin deficiency [pellagra]	0.000	0.383	0.617
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.612	0.388	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.388	0.612
E14.5 With peripheral circulatory complications	0.000	0.388	0.612
T38.1 Thyroid hormones and substitutes	0.597	0.403	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.596	0.404	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.596	0.404	0.000
T47.7 Emetics	0.596	0.404	0.000
T47.6 Antidiarrhoeal drugs	0.596	0.404	0.000
T47.5 Digestants	0.596	0.404	0.000
T47.3 Saline and osmotic laxatives	0.596	0.404	0.000
T47.2 Stimulant laxatives	0.596	0.404	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.595	0.405	0.000
T42.0 Hydantoin derivatives	0.594	0.405	0.000
E14.4 With neurological complications	0.000	0.406	0.594
T47.1 Other antacids and anti-gastric-secretion drugs	0.579	0.421	0.000
E03.1 Congenital hypothyroidism without goitre	0.000	0.425	0.575
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.575	0.425	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.575	0.425	0.000
T48.4 Expectorants	0.575	0.425	0.000
T48.3 Antitussives	0.575	0.425	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.575	0.425	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.575	0.425	0.000
T48.0 Oxytocic drugs	0.575	0.425	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.575	0.425	0.000
E14.8 With unspecified complications	0.000	0.429	0.571
T45.5 Anticoagulants	0.564	0.436	0.000
E53.9 Vitamin B deficiency, unspecified	0.000	0.439	0.561
T38.9 Other and unspecified hormone antagonists	0.558	0.442	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.558	0.442	0.000
T38.7 Androgens and anabolic congeners	0.558	0.442	0.000
T38.5 Other oestrogens and progestogens	0.558	0.442	0.000
T38.4 Oral contraceptives	0.558	0.442	0.000
T38.2 Antithyroid drugs	0.558	0.442	0.000
T38.0 Glucocorticoids and synthetic analogues	0.558	0.442	0.000
E40-E46 Malnutrition	0.000	0.449	0.551
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.547	0.452	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.547	0.452	0.000
T46.7 Peripheral vasodilators	0.547	0.452	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.547	0.452	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.455	0.545
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.544	0.455	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.460	0.540
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.533	0.467	0.000
E06.3 Autoimmune thyroiditis	0.000	0.468	0.532
E55.0 Rickets, active	0.000	0.471	0.529
T46.5 Other antihypertensive drugs, not elsewhere classified	0.522	0.478	0.000
T45.2 Vitamins, not elsewhere classified	0.518	0.482	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.517	0.483	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.486	0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.486	0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.486	0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.486	0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.486	0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.486	0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.486	0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.486	0.514
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.514	0.486	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.514	0.486	0.000
T37.5 Antiviral drugs	0.514	0.486	0.000
T37.4 Anthelminthics	0.514	0.486	0.000
T37.3 Other antiprotozoal drugs	0.514	0.486	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.514	0.486	0.000
T37.1 Antimycobacterial drugs	0.514	0.486	0.000
T37.0 Sulphonamides	0.514	0.486	0.000
T41.5 Therapeutic gases	0.514	0.486	0.000
T41.4 Anaesthetic, unspecified	0.514	0.486	0.000
T41.3 Local anaesthetics	0.514	0.486	0.000
T41.2 Other and unspecified general anaesthetics	0.514	0.486	0.000
T41.1 Intravenous anaesthetics	0.514	0.486	0.000
T41.0 Inhaled anaesthetics	0.514	0.486	0.000
T49.9 Topical agent, unspecified	0.514	0.486	0.000
T49.8 Other topical agents	0.514	0.486	0.000
T49.7 Dental drugs, topically applied	0.514	0.486	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.514	0.486	0.000
T49.5 Ophthalmological drugs and preparations	0.514	0.486	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.514	0.486	0.000
T49.3 Emollients, demulcents and protectants	0.514	0.486	0.000
T49.2 Local astringents and local detergents	0.514	0.486	0.000
T49.1 Antipruritics	0.514	0.486	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.514	0.486	0.000
E12.9 Without complications	0.000	0.486	0.514
E12.8 With unspecified complications	0.000	0.486	0.514
E12.7 With multiple complications	0.000	0.486	0.514
E12.6 With other specified complications	0.000	0.486	0.514
E12.5 With peripheral circulatory complications	0.000	0.486	0.514
E12.4 With neurological complications	0.000	0.486	0.514
E12.3 With ophthalmic complications	0.000	0.486	0.514
E12.2 With renal complications	0.000	0.486	0.514
E12.1 With ketoacidosis	0.000	0.486	0.514
E12.0 With coma	0.000	0.486	0.514
E53.8 Deficiency of other specified B group vitamins	0.000	0.493	0.507
T36.9 Systemic antibiotic, unspecified	0.505	0.494	0.000
T36.8 Other systemic antibiotics	0.505	0.494	0.000
T36.7 Antifungal antibiotics, systemically used	0.505	0.494	0.000
T36.6 Rifamycins	0.505	0.494	0.000
T36.5 Aminoglycosides	0.505	0.494	0.000
T36.4 Tetracyclines	0.505	0.494	0.000
T36.3 Macrolides	0.505	0.494	0.000
T36.2 Chloramphenicol group	0.505	0.494	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.505	0.494	0.000
E51.2 Wernicke's encephalopathy	0.000	0.501	0.499
E53.1 Pyridoxine deficiency	0.000	0.505	0.495
E53.0 Riboflavin deficiency	0.000	0.505	0.495
E13 Other specified diabetes mellitus	0.000	0.505	0.494
T36.0 Penicillins	0.494	0.506	0.000
E61 Deficiency of other nutrient elements	0.000	0.517	0.483
E06.5 Other chronic thyroiditis	0.000	0.522	0.478
E06.4 Drug-induced thyroiditis	0.000	0.522	0.478
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.522	0.478
E06.0 Acute thyroiditis	0.000	0.522	0.478
E04.2 Non-toxic multinodular goitre	0.000	0.523	0.477
E07.1 Dyshormogenetic goitre	0.000	0.526	0.473
E07.0 Hypersecretion of calcitonin	0.000	0.526	0.473
E51.9 Thiamine deficiency, unspecified	0.000	0.534	0.466
E51.8 Other manifestations of thiamine deficiency	0.000	0.534	0.466
E51.1 Beriberi	0.000	0.534	0.466
E03.8 Other specified hypothyroidism	0.000	0.535	0.464
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.550	0.450
K90.3 Pancreatic steatorrhoea	0.000	0.553	0.447
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.553	0.447
K90.1 Tropical sprue	0.000	0.553	0.447
E50.9 Vitamin A deficiency, unspecified	0.000	0.557	0.442
E50.8 Other manifestations of vitamin A deficiency	0.000	0.557	0.442
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.557	0.442
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.557	0.442
E50.5 Vitamin A deficiency with night blindness	0.000	0.557	0.442
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.557	0.442
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.557	0.442
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.557	0.442
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.557	0.442
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.557	0.442
E56.9 Vitamin deficiency, unspecified	0.000	0.557	0.442
E56.8 Deficiency of other vitamins	0.000	0.557	0.442
E56.1 Deficiency of vitamin K	0.000	0.557	0.442
E56.0 Deficiency of vitamin E	0.000	0.557	0.442
E63.9 Nutritional deficiency, unspecified	0.000	0.557	0.442
E63.8 Other specified nutritional deficiencies	0.000	0.557	0.442
E63.1 Imbalance of constituents of food intake	0.000	0.557	0.442
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.557	0.442
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.557	0.442
E64.8 Sequelae of other nutritional deficiencies	0.000	0.557	0.442
E64.3 Sequelae of rickets	0.000	0.557	0.442
E64.2 Sequelae of vitamin C deficiency	0.000	0.557	0.442
E64.1 Sequelae of vitamin A deficiency	0.000	0.557	0.442
E64.0 Sequelae of protein-energy malnutrition	0.000	0.557	0.442
K90.8 Other intestinal malabsorption	0.000	0.568	0.432
M07.39 Other psoriatic arthropathies (Site unspecified)	0.422	0.578	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.421	0.579	0.000
E14.9 Without complications	0.000	0.580	0.420
M07.30 Other psoriatic arthropathies (Multiple sites)	0.419	0.581	0.000
M07.3 Other psoriatic arthropathies	0.419	0.581	0.000
E06.9 Thyroiditis, unspecified	0.000	0.585	0.415
E06.1 Subacute thyroiditis	0.000	0.585	0.415
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.605	0.395
E45 Retarded development following protein-energy malnutrition	0.000	0.605	0.395
E43 Unspecified severe protein-energy malnutrition	0.000	0.605	0.395
E42 Marasmic kwashiorkor	0.000	0.605	0.395
E41 Nutritional marasmus	0.000	0.605	0.395
E40 Kwashiorkor	0.000	0.605	0.395
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.001	0.622	0.377
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.374	0.626	0.000
E04.1 Non-toxic single thyroid nodule	0.000	0.637	0.363
E13.8 With unspecified complications	0.000	0.645	0.354
E13.7 With multiple complications	0.000	0.645	0.354
E13.6 With other specified complications	0.000	0.645	0.354
E13.5 With peripheral circulatory complications	0.000	0.645	0.354
E13.4 With neurological complications	0.000	0.645	0.354
E13.2 With renal complications	0.000	0.645	0.354
E13.1 With ketoacidosis	0.000	0.645	0.354
E13.0 With coma	0.000	0.645	0.354
E61.9 Deficiency of nutrient element, unspecified	0.000	0.654	0.346
E61.8 Deficiency of other specified nutrient elements	0.000	0.654	0.346
E61.7 Deficiency of multiple nutrient elements	0.000	0.654	0.346
E61.6 Vanadium deficiency	0.000	0.654	0.346
E61.5 Molybdenum deficiency	0.000	0.654	0.346
E61.4 Chromium deficiency	0.000	0.654	0.346
E61.3 Manganese deficiency	0.000	0.654	0.346
E61.0 Copper deficiency	0.000	0.654	0.346
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.327	0.673	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.321	0.678	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.320	0.680	0.000
E13.3 With ophthalmic complications	0.000	0.684	0.315
E61.2 Magnesium deficiency	0.000	0.687	0.313
M07.38 Other psoriatic arthropathies (Other)	0.300	0.699	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.300	0.699	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.300	0.699	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.300	0.699	0.000
E65-E68 Obesity and other hyperalimentation	0.000	0.711	0.289
M07.34 Other psoriatic arthropathies (Hand)	0.287	0.713	0.000
E44.1 Mild protein-energy malnutrition	0.000	0.716	0.283
E44.0 Moderate protein-energy malnutrition	0.000	0.716	0.283
T40.5 Cocaine	0.282	0.717	0.000
E07.8 Other specified disorders of thyroid	0.001	0.719	0.280
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.268	0.732	0.000
T40.8 Lysergide [LSD]	0.268	0.732	0.000
T40.7 Cannabis (derivatives)	0.268	0.732	0.000
T40.3 Methadone	0.268	0.732	0.000
T40.1 Heroin	0.268	0.732	0.000
T40.0 Opium	0.268	0.732	0.000
E61.1 Iron deficiency	0.000	0.735	0.265
T40.6 Other and unspecified narcotics	0.251	0.749	0.000
L40-L45 Papulosquamous disorders	0.239	0.760	0.000
E46 Unspecified protein-energy malnutrition	0.000	0.771	0.229
E13.9 Without complications	0.001	0.788	0.211
E67 Other hyperalimentation	0.000	0.792	0.207
E68 Sequelae of hyperalimentation	0.000	0.792	0.207
M06.9 Rheumatoid arthritis, unspecified	0.000	0.797	0.203
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.800	0.200
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.807	0.193
T40.4 Other synthetic narcotics	0.189	0.811	0.000
L41 Parapsoriasis	0.187	0.812	0.000
M07 Psoriatic and enteropathic arthropathies	0.180	0.817	0.004
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.820	0.180
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.821	0.179
H36.0 Diabetic retinopathy	0.000	0.823	0.177
L44 Other papulosquamous disorders	0.172	0.828	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.172	0.828	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.829	0.171
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.841	0.159
L42 Pityriasis rosea	0.155	0.844	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.845	0.155
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.847	0.153
L41.1 Pityriasis lichenoides chronica	0.150	0.849	0.000
E67.8 Other specified hyperalimentation	0.000	0.851	0.149
E67.3 Hypervitaminosis D	0.000	0.851	0.149
E67.2 Megavitamin-B6 syndrome	0.000	0.851	0.149
E67.1 Hypercarotenaemia	0.000	0.851	0.149
E67.0 Hypervitaminosis A	0.000	0.851	0.149
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.851	0.149
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.852	0.148
Z91.5 Personal history of self-harm	0.144	0.856	0.000
L41.9 Parapsoriasis, unspecified	0.134	0.865	0.000
L41.8 Other parapsoriasis	0.134	0.865	0.000
L41.5 Retiform parapsoriasis	0.134	0.865	0.000
L41.4 Large plaque parapsoriasis	0.134	0.865	0.000
L41.3 Small plaque parapsoriasis	0.134	0.865	0.000
L41.2 Lymphomatoid papulosis	0.134	0.865	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.134	0.865	0.000
M07.6 Other enteropathic arthropathies	0.129	0.868	0.003
M07.5 Arthropathy in ulcerative colitis	0.129	0.868	0.003
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.129	0.868	0.003
M07.2 Psoriatic spondylitis	0.129	0.868	0.003
M07.1 Arthritis mutilans	0.129	0.868	0.003
M07.0 Distal interphalangeal psoriatic arthropathy	0.129	0.868	0.003
L44.9 Papulosquamous disorder, unspecified	0.123	0.876	0.000
L44.8 Other specified papulosquamous disorders	0.123	0.876	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.123	0.876	0.000
L44.3 Lichen ruber moniliformis	0.123	0.876	0.000
L44.2 Lichen striatus	0.123	0.876	0.000
L44.1 Lichen nitidus	0.123	0.876	0.000
L44.0 Pityriasis rubra pilaris	0.123	0.876	0.000
N23 Unspecified renal colic	0.123	0.877	0.000
E65 Localised adiposity	0.001	0.878	0.121
T40.2 Other opioids	0.120	0.880	0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.093	0.905	0.002
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.093	0.905	0.002
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.093	0.905	0.002
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.093	0.905	0.002
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.093	0.905	0.002
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.093	0.905	0.002
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.093	0.905	0.002
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.093	0.905	0.002
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.093	0.905	0.002
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.093	0.905	0.002
M07.19 Arthritis mutilans (Site unspecified)	0.093	0.905	0.002
M07.18 Arthritis mutilans (Other)	0.093	0.905	0.002
M07.17 Arthritis mutilans (Ankle and foot)	0.093	0.905	0.002
M07.16 Arthritis mutilans (Lower leg)	0.093	0.905	0.002
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.093	0.905	0.002
M07.14 Arthritis mutilans (Hand)	0.093	0.905	0.002
M07.13 Arthritis mutilans (Forearm)	0.093	0.905	0.002
M07.12 Arthritis mutilans (Upper arm)	0.093	0.905	0.002
M07.11 Arthritis mutilans (Shoulder region)	0.093	0.905	0.002
M07.10 Arthritis mutilans (Multiple sites)	0.093	0.905	0.002
M07.29 Psoriatic spondylitis (Site unspecified)	0.093	0.905	0.002
M07.28 Psoriatic spondylitis (Other)	0.093	0.905	0.002
M07.27 Psoriatic spondylitis (Ankle and foot)	0.093	0.905	0.002
M07.26 Psoriatic spondylitis (Lower leg)	0.093	0.905	0.002
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.093	0.905	0.002
M07.24 Psoriatic spondylitis (Hand)	0.093	0.905	0.002
M07.23 Psoriatic spondylitis (Forearm)	0.093	0.905	0.002
M07.22 Psoriatic spondylitis (Upper arm)	0.093	0.905	0.002
M07.21 Psoriatic spondylitis (Shoulder region)	0.093	0.905	0.002
M07.20 Psoriatic spondylitis (Multiple sites)	0.093	0.905	0.002
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.093	0.905	0.002
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.093	0.905	0.002
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.093	0.905	0.002
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.093	0.905	0.002
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.093	0.905	0.002
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.093	0.905	0.002
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.093	0.905	0.002
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.093	0.905	0.002
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.093	0.905	0.002
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.093	0.905	0.002
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.093	0.905	0.002
M07.58 Arthropathy in ulcerative colitis (Other)	0.093	0.905	0.002
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.093	0.905	0.002
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.093	0.905	0.002
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.093	0.905	0.002
M07.54 Arthropathy in ulcerative colitis (Hand)	0.093	0.905	0.002
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.093	0.905	0.002
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.093	0.905	0.002
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.093	0.905	0.002
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.093	0.905	0.002
M07.69 Other enteropathic arthropathies (Site unspecified)	0.093	0.905	0.002
M07.68 Other enteropathic arthropathies (Other)	0.093	0.905	0.002
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.093	0.905	0.002
M07.66 Other enteropathic arthropathies (Lower leg)	0.093	0.905	0.002
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.093	0.905	0.002
M07.64 Other enteropathic arthropathies (Hand)	0.093	0.905	0.002
M07.63 Other enteropathic arthropathies (Forearm)	0.093	0.905	0.002
M07.62 Other enteropathic arthropathies (Upper arm)	0.093	0.905	0.002
M07.61 Other enteropathic arthropathies (Shoulder region)	0.093	0.905	0.002
M07.60 Other enteropathic arthropathies (Multiple sites)	0.093	0.905	0.002
H36 Retinal disorders in diseases classified elsewhere	0.000	0.916	0.084
L43 Lichen planus	0.076	0.922	0.001
M06 Other rheumatoid arthritis	0.002	0.926	0.073
H36.8 Other retinal disorders in diseases classified elsewhere	0.000	0.940	0.060
N20-N23 Urolithiasis	0.058	0.942	0.000
M06.4 Inflammatory polyarthropathy	0.001	0.943	0.056
L43.3 Subacute (active) lichen planus	0.055	0.944	0.001
L43.2 Lichenoid drug reaction	0.055	0.944	0.001
L43.1 Bullous lichen planus	0.055	0.944	0.001
L43.0 Hypertrophic lichen planus	0.055	0.944	0.001
K90-K93 Other diseases of the digestive system	0.000	0.946	0.054
M06.8 Other specified rheumatoid arthritis	0.001	0.946	0.052
M06.2 Rheumatoid bursitis	0.001	0.946	0.052
M06.1 Adult-onset Still's disease	0.001	0.946	0.052
N20 Calculus of kidney and ureter	0.052	0.948	0.000
E11 Non-insulin-dependent diabetes mellitus	0.000	0.949	0.051
N20.0 Calculus of kidney	0.050	0.950	0.000
M06.3 Rheumatoid nodule	0.001	0.951	0.048
E11.3 With ophthalmic complications	0.000	0.953	0.047
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.001	0.954	0.045
M06.0 Seronegative rheumatoid arthritis	0.001	0.956	0.043
N22 Calculus of urinary tract in diseases classified elsewhere	0.042	0.958	0.000
N20.9 Urinary calculus, unspecified	0.042	0.958	0.000
L43.8 Other lichen planus	0.040	0.958	0.001
N20.1 Calculus of ureter	0.041	0.959	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.001	0.959	0.040
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.001	0.959	0.040
M06.46 Inflammatory polyarthropathy (Lower leg)	0.001	0.959	0.040
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.001	0.959	0.040
M06.44 Inflammatory polyarthropathy (Hand)	0.001	0.959	0.040
M06.43 Inflammatory polyarthropathy (Forearm)	0.001	0.959	0.040
M06.42 Inflammatory polyarthropathy (Upper arm)	0.001	0.959	0.040
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.001	0.959	0.040
E66 Obesity	0.000	0.959	0.041
E20-E35 Disorders of other endocrine glands	0.021	0.960	0.019
E11.8 With unspecified complications	0.000	0.960	0.040

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations