TreeWAS – Variant ID: rs10951138

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S43.0 Dislocation of shoulder joint	0.099	0.901	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.052	0.948	0.000
N32.0 Bladder-neck obstruction	0.048	0.952	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.039	0.961	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.028	0.972	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.028	0.972	0.000
S43.4 Sprain and strain of shoulder joint	0.028	0.972	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.028	0.972	0.000
S43.2 Dislocation of sternoclavicular joint	0.028	0.972	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.027	0.973	0.000
I08 Multiple valve diseases	0.027	0.973	0.000
I08.8 Other multiple valve diseases	0.025	0.975	0.000
S43.1 Dislocation of acromioclavicular joint	0.024	0.975	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.020	0.979	0.000
I08.9 Multiple valve disease, unspecified	0.020	0.980	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.015	0.984	0.000
Z83.7 Family history of diseases of the digestive system	0.015	0.985	0.000
I05-I09 Chronic rheumatic heart diseases	0.013	0.987	0.000
N21.0 Calculus in bladder	0.013	0.987	0.000
H33.3 Retinal breaks without detachment	0.000	0.987	0.013
I05 Rheumatic mitral valve diseases	0.012	0.988	0.000
I05.9 Mitral valve disease, unspecified	0.011	0.989	0.000
R47.8 Other and unspecified speech disturbances	0.000	0.989	0.011
I05.8 Other mitral valve diseases	0.010	0.990	0.000
I05.1 Rheumatic mitral insufficiency	0.010	0.990	0.000
I05.2 Mitral stenosis with insufficiency	0.010	0.990	0.000
I06 Rheumatic aortic valve diseases	0.010	0.990	0.000
H33.1 Retinoschisis and retinal cysts	0.000	0.991	0.009
I05.0 Mitral stenosis	0.009	0.991	0.000
N21 Calculus of lower urinary tract	0.009	0.991	0.000
R47.0 Dysphasia and aphasia	0.000	0.991	0.009
H33 Retinal detachments and breaks	0.000	0.991	0.009
I09 Other rheumatic heart diseases	0.008	0.991	0.000
R47 Speech disturbances, not elsewhere classified	0.000	0.992	0.008
N21.8 Other lower urinary tract calculus	0.008	0.992	0.000
N21.1 Calculus in urethra	0.007	0.993	0.000
S69.9 Unspecified injury of wrist and hand	0.007	0.993	0.000
I06.0 Rheumatic aortic stenosis	0.007	0.993	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.007	0.993	0.000
I06.8 Other rheumatic aortic valve diseases	0.007	0.993	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.007	0.993	0.000
I06.1 Rheumatic aortic insufficiency	0.007	0.993	0.000
H33.2 Serous retinal detachment	0.000	0.993	0.007
I07 Rheumatic tricuspid valve diseases	0.006	0.993	0.001
S40-S49 Injuries to the shoulder and upper arm	0.007	0.993	0.000
H33.4 Traction detachment of retina	0.000	0.993	0.007
N21.9 Calculus of lower urinary tract, unspecified	0.006	0.993	0.000
I08.0 Disorders of both mitral and aortic valves	0.006	0.994	0.000
I09.8 Other specified rheumatic heart diseases	0.006	0.994	0.000
I09.2 Chronic rheumatic pericarditis	0.006	0.994	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.006	0.994	0.000
I09.0 Rheumatic myocarditis	0.006	0.994	0.000
Y54.5 Other diuretics	0.000	0.994	0.006
Y40.0 Penicillins	0.000	0.994	0.006
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.000	0.994	0.006
Y54.3 Benzothiadiazine derivatives	0.000	0.994	0.006
Y40 Systemic antibiotics	0.000	0.994	0.006
Y40.9 Systemic antibiotic, unspecified	0.000	0.994	0.006
S46 Injury of muscle and tendon at shoulder and upper arm level	0.005	0.994	0.000
H33.5 Other retinal detachments	0.000	0.995	0.005
S40 Superficial injury of shoulder and upper arm	0.005	0.995	0.000
R47.1 Dysarthria and anarthria	0.000	0.995	0.005
I09.9 Rheumatic heart disease, unspecified	0.005	0.995	0.000
Y40.8 Other systemic antibiotics	0.000	0.995	0.005
I07.9 Tricuspid valve disease, unspecified	0.005	0.995	0.001
I07.8 Other tricuspid valve diseases	0.005	0.995	0.001
I07.2 Tricuspid stenosis with insufficiency	0.005	0.995	0.001
I07.0 Tricuspid stenosis	0.005	0.995	0.001
S48 Traumatic amputation of shoulder and upper arm	0.005	0.995	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.005	0.995	0.000
S44 Injury of nerves at shoulder and upper arm level	0.005	0.995	0.000
S47 Crushing injury of shoulder and upper arm	0.005	0.995	0.000
K50.9 Crohn's disease, unspecified	0.000	0.995	0.005
S46.2 Injury of muscle and tendon of other parts of biceps	0.005	0.995	0.000
R23.8 Other and unspecified skin changes	0.000	0.995	0.005
Z73.9 Problem related to life-management difficulty, unspecified	0.005	0.995	0.000
S41 Open wound of shoulder and upper arm	0.005	0.995	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.005	0.995	0.000
H33.0 Retinal detachment with retinal break	0.000	0.995	0.005
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.000	0.995	0.005
Y54.8 Agents affecting uric acid metabolism	0.000	0.995	0.004
Y54.9 Mineral salts, not elsewhere classified	0.000	0.995	0.004
Y54.7 Agents affecting calcification	0.000	0.995	0.004
Y54.6 Electrolytic, caloric and water-balance agents	0.000	0.995	0.004
Y54.2 Carbonic-anhydrase inhibitors	0.000	0.995	0.004
Y54.0 Mineralocorticoids	0.000	0.995	0.004
Y40.5 Aminoglycosides	0.000	0.996	0.004
Y40.7 Antifungal antibiotics, systemically used	0.000	0.996	0.004
Y40.6 Rifamycins	0.000	0.996	0.004
Y40.4 Tetracyclines	0.000	0.996	0.004
Y40.2 Chloramphenicol group	0.000	0.996	0.004
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.000	0.996	0.004
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.004	0.996	0.000
Y54.4 Loop [high-ceiling] diuretics	0.000	0.996	0.004
Y46 Antiepileptics and anti-Parkinsonism drugs	0.000	0.996	0.004
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.004	0.996	0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.004	0.996	0.000
S46.3 Injury of muscle and tendon of triceps	0.004	0.996	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.004	0.996	0.000
Y40.3 Macrolides	0.000	0.996	0.004
M47.86 Other spondylosis (Lumbar region)	0.004	0.996	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.004	0.996	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.004	0.996	0.000
Z89 Acquired absence of limb	0.004	0.996	0.000
Y48 Anaesthetics and therapeutic gases	0.000	0.996	0.004
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.004	0.996	0.000
Y46.4 Iminostilbenes	0.000	0.996	0.004
Z89.6 Acquired absence of leg above knee	0.004	0.996	0.000
Y44 Agents primarily affecting blood constituents	0.000	0.996	0.004
S40.8 Other superficial injuries of shoulder and upper arm	0.004	0.996	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.004	0.996	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.004	0.996	0.000
R23.1 Pallor	0.000	0.996	0.004
S44.9 Injury of unspecified nerve at shoulder and upper arm level	0.004	0.996	0.000
S44.8 Injury of other nerves at shoulder and upper arm level	0.004	0.996	0.000
S44.7 Injury of multiple nerves at shoulder and upper arm level	0.004	0.996	0.000
S44.5 Injury of cutaneous sensory nerve at shoulder and upper arm level	0.004	0.996	0.000
S44.4 Injury of musculocutaneous nerve	0.004	0.996	0.000
S44.3 Injury of axillary nerve	0.004	0.996	0.000
S44.2 Injury of radial nerve at upper arm level	0.004	0.996	0.000
S44.1 Injury of median nerve at upper arm level	0.004	0.996	0.000
S44.0 Injury of ulnar nerve at upper arm level	0.004	0.996	0.000
S45.9 Injury of unspecified blood vessel at shoulder and upper arm level	0.004	0.996	0.000
S45.8 Injury of other blood vessels at shoulder and upper arm level	0.004	0.996	0.000
S45.7 Injury of multiple blood vessels at shoulder and upper arm level	0.004	0.996	0.000
S45.3 Injury of superficial vein at shoulder and upper arm level	0.004	0.996	0.000
S45.2 Injury of axillary or brachial vein	0.004	0.996	0.000
S45.1 Injury of brachial artery	0.004	0.996	0.000
S45.0 Injury of axillary artery	0.004	0.996	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.004	0.996	0.000
S48.9 Traumatic amputation of shoulder and upper arm, level unspecified	0.004	0.996	0.000
S48.1 Traumatic amputation at level between shoulder and elbow	0.004	0.996	0.000
S48.0 Traumatic amputation at shoulder joint	0.004	0.996	0.000
Z89.5 Acquired absence of leg at or below knee	0.004	0.996	0.000
S41.1 Open wound of upper arm	0.004	0.996	0.000
Y44.2 Anticoagulants	0.000	0.996	0.004
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.004	0.996	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.004	0.996	0.000
M89.0 Algoneurodystrophy	0.004	0.996	0.000
Z89.2 Acquired absence of upper limb above wrist	0.004	0.996	0.000
Z89.4 Acquired absence of foot and ankle	0.004	0.996	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.000	0.996	0.004
S40.0 Contusion of shoulder and upper arm	0.004	0.996	0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.004	0.996	0.000
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.003	0.996	0.000
S41.7 Multiple open wounds of shoulder and upper arm	0.003	0.996	0.000
R23 Other skin changes	0.000	0.996	0.004
N49.2 Inflammatory disorders of scrotum	0.004	0.996	0.000
R91 Abnormal findings on diagnostic imaging of lung	0.004	0.996	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.000	0.996	0.003
Z89.9 Acquired absence of limb, unspecified	0.003	0.996	0.000
O03.9 Complete or unspecified, without complication	0.000	0.996	0.004
Y46.6 Other and unspecified antiepileptics	0.000	0.996	0.003
Y46.2 Hydantoin derivatives	0.000	0.996	0.003
M89.09 Algoneurodystrophy (Site unspecified)	0.003	0.996	0.000
S49.8 Other specified injuries of shoulder and upper arm	0.003	0.997	0.000
Y48.4 Anaesthetic, unspecified	0.000	0.997	0.003
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.000	0.997	0.003
Y52 Agents primarily affecting the cardiovascular system	0.000	0.997	0.003
Y48.3 Local anaesthetics	0.000	0.997	0.003
Y48.2 Other and unspecified general anaesthetics	0.000	0.997	0.003
Y49.5 Other antipsychotics and neuroleptics	0.000	0.997	0.003
M89.07 Algoneurodystrophy (Ankle and foot)	0.003	0.997	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.000	0.997	0.003
Y46.8 Antispasticity drugs	0.000	0.997	0.003
Y46.7 Anti-Parkinsonism drugs	0.000	0.997	0.003
Y46.5 Valproic acid	0.000	0.997	0.003
Y46.3 Deoxybarbiturates	0.000	0.997	0.003
Y46.1 Oxazolidinediones	0.000	0.997	0.003
Y46.0 Succinimides	0.000	0.997	0.003
Y47 Sedatives, hypnotics and antianxiety drugs	0.000	0.997	0.003
S49.7 Multiple injuries of shoulder and upper arm	0.003	0.997	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.997	0.003
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M79.79 Fibromyalgia (Site unspecified)	0.000	0.997	0.003
S69 Other and unspecified injuries of wrist and hand	0.003	0.997	0.000
R23.4 Changes in skin texture	0.000	0.997	0.003
Y41 Other systemic anti-infectives and antiparasitics	0.000	0.997	0.003
Y52.3 Coronary vasodilators, not elsewhere classified	0.000	0.997	0.003
Z89.8 Acquired absence of upper and lower limbs [any level]	0.003	0.997	0.000
Z89.3 Acquired absence of both upper limbs [any level]	0.003	0.997	0.000
Z89.1 Acquired absence of hand and wrist	0.003	0.997	0.000
Y58 Bacterial vaccines	0.000	0.997	0.003
M89.06 Algoneurodystrophy (Lower leg)	0.003	0.997	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.000	0.997	0.003
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.003	0.997	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.000	0.997	0.003
Y44.7 Plasma substitutes	0.000	0.997	0.003
Y44.6 Natural blood and blood products	0.000	0.997	0.003
Y44.5 Thrombolytic drugs	0.000	0.997	0.003
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.000	0.997	0.003
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.997	0.003
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.000	0.997	0.003
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.000	0.997	0.003
Y48.5 Therapeutic gases	0.000	0.997	0.003
Y48.1 Parenteral anaesthetics	0.000	0.997	0.003
Y48.0 Inhaled anaesthetics	0.000	0.997	0.003
M89 Other disorders of bone	0.003	0.997	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.003	0.997	0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.003	0.997	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.003	0.997	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.003	0.997	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.003	0.997	0.000
G63.2 Diabetic polyneuropathy	0.003	0.997	0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.003	0.997	0.000
M89.08 Algoneurodystrophy (Other)	0.003	0.997	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.003	0.997	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.003	0.997	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.003	0.997	0.000
M95.0 Acquired deformity of nose	0.003	0.997	0.000
Y59 Other and unspecified vaccines and biological substances	0.000	0.997	0.003
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.997	0.003
R23.2 Flushing	0.000	0.997	0.003
K50 Crohn's disease [regional enteritis]	0.000	0.997	0.003
M90.7 Fracture of bone in neoplastic disease	0.003	0.997	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.000	0.997	0.003
K50.0 Crohn's disease of small intestine	0.000	0.997	0.003
N87.9 Dysplasia of cervix uteri, unspecified	0.003	0.997	0.000
D12.7 Rectosigmoid junction	0.003	0.997	0.000
Y49.9 Psychotropic drug, unspecified	0.000	0.997	0.003
Y49.8 Other psychotropic drugs, not elsewhere classified	0.000	0.997	0.003
Y49.7 Psychostimulants with abuse potential	0.000	0.997	0.003
Y49.6 Psychodysleptics [hallucinogens]	0.000	0.997	0.003
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.997	0.003
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.997	0.003
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.997	0.003
Y49.0 Tricyclic and tetracyclic antidepressants	0.000	0.997	0.003
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.997	0.003
M89.04 Algoneurodystrophy (Hand)	0.003	0.997	0.000
S41.0 Open wound of shoulder	0.002	0.997	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.997	0.003
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.003	0.997	0.000
M89.3 Hypertrophy of bone	0.003	0.997	0.000
I27.0 Primary pulmonary hypertension	0.003	0.997	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.997	0.003
M47.2 Other spondylosis with radiculopathy	0.003	0.997	0.000
Y56.9 Topical agent, unspecified	0.000	0.997	0.003
Y56.8 Other topical agents	0.000	0.997	0.003
Y56.7 Dental drugs, topically applied	0.000	0.997	0.003
Y56.6 Otorhinolaryngological drugs and preparations	0.000	0.997	0.003
Y56.5 Ophthalmological drugs and preparations	0.000	0.997	0.003
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.997	0.003
Y56.3 Emollients, demulcents and protectants	0.000	0.997	0.003
Y56.2 Local astringents and local detergents	0.000	0.997	0.003
Y56.1 Antipruritics	0.000	0.997	0.003
Y57 Other and unspecified drugs and medicaments	0.000	0.997	0.003
R47-R49 Symptoms and signs involving speech and voice	0.000	0.997	0.003
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.003	0.997	0.000
M89.03 Algoneurodystrophy (Forearm)	0.003	0.997	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.003	0.997	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.997	0.003
Y52.8 Antivaricose drugs, including sclerosing agents	0.000	0.997	0.003
Y52.7 Peripheral vasodilators	0.000	0.997	0.003
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.997	0.003
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.003	0.997	0.000
Y50.9 Central nervous system stimulant, unspecified	0.000	0.997	0.002
Y50.8 Other central nervous system stimulants	0.000	0.997	0.002
Y50.2 Methylxanthines, not elsewhere classified	0.000	0.997	0.002
Y50.1 Opioid receptor antagonists	0.000	0.997	0.002
Y50.0 Analeptics	0.000	0.997	0.002
M90 Osteopathies in diseases classified elsewhere	0.003	0.997	0.000
M89.8 Other specified disorders of bone	0.003	0.997	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.000	0.997	0.002
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.000	0.997	0.002
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.000	0.997	0.002
Y47.4 Bromine compounds	0.000	0.997	0.002
Y47.3 Paraldehyde	0.000	0.997	0.002
Y47.2 Chloral derivatives	0.000	0.997	0.002
Y47.0 Barbiturates, not elsewhere classified	0.000	0.997	0.002
Z35.1 Supervision of pregnancy with history of abortive outcome	0.003	0.997	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.000	0.997	0.003
I82.9 Embolism and thrombosis of unspecified vein	0.000	0.997	0.003
S69.7 Multiple injuries of wrist and hand	0.002	0.997	0.000
Y47.1 Benzodiazepines	0.000	0.997	0.002
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.997	0.002
Y41.4 Anthelminthics	0.000	0.997	0.002
Y41.3 Other antiprotozoal drugs	0.000	0.997	0.002
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.997	0.002
Y41.1 Antimycobacterial drugs	0.000	0.997	0.002
Y58.9 Other and unspecified bacterial vaccines	0.000	0.997	0.002
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.000	0.997	0.002
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.000	0.997	0.002
Y58.5 Diphtheria vaccine	0.000	0.997	0.002
Y58.4 Tetanus vaccine	0.000	0.997	0.002
Y58.3 Plague vaccine	0.000	0.997	0.002
Y58.2 Cholera vaccine	0.000	0.997	0.002
Y58.1 Typhoid and paratyphoid vaccine	0.000	0.997	0.002
R23.3 Spontaneous ecchymoses	0.000	0.997	0.002
S69.8 Other specified injuries of wrist and hand	0.002	0.997	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.000	0.997	0.002
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.997	0.002
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.000	0.997	0.002
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.997	0.002
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.997	0.002
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.000	0.997	0.002
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.997	0.002
Y51.1 Other parasympathomimetics [cholinergics]	0.000	0.997	0.002
Y51.0 Anticholinesterase agents	0.000	0.997	0.002
M89.6 Osteopathy after poliomyelitis	0.002	0.997	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.002	0.997	0.000
M89.2 Other disorders of bone development and growth	0.002	0.997	0.000
M89.1 Epiphyseal arrest	0.002	0.997	0.000
O14.9 Preeclampsia, unspecified	0.003	0.997	0.000
M89.5 Osteolysis	0.002	0.997	0.000
Y41.0 Sulphonamides	0.000	0.997	0.002
C90.0 Multiple myeloma	0.000	0.997	0.003
M89.37 Hypertrophy of bone (Ankle and foot)	0.002	0.997	0.000
M86-M90 Other osteopathies	0.002	0.997	0.000
M89.88 Other specified disorders of bone (Other)	0.002	0.998	0.000
Y57.8 Other drugs and medicaments	0.000	0.998	0.002
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.002	0.998	0.000
R23.0 Cyanosis	0.000	0.998	0.002
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.998	0.002
Y55.5 Anticommon cold drugs	0.000	0.998	0.002
Y55.4 Expectorants	0.000	0.998	0.002
Y55.3 Antitussives	0.000	0.998	0.002
Y55.2 Other and unspecified agents primarily acting on muscles	0.000	0.998	0.002
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.998	0.002
Y55.0 Oxytocic drugs	0.000	0.998	0.002
Y59.9 Vaccine or biological substance, unspecified	0.000	0.998	0.002
Y59.8 Other specified vaccines and biological substances	0.000	0.998	0.002
Y59.2 Protozoal vaccines	0.000	0.998	0.002
Y59.1 Rickettsial vaccines	0.000	0.998	0.002
Y59.0 Viral vaccines	0.000	0.998	0.002
M89.38 Hypertrophy of bone (Other)	0.002	0.998	0.000
D12.3 Transverse colon	0.002	0.998	0.000
I07.1 Tricuspid insufficiency	0.001	0.998	0.001
Y58.0 BCG vaccine	0.000	0.998	0.002
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.002	0.998	0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.002	0.998	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.002	0.998	0.000
M90.74 Fracture of bone in neoplastic disease (Hand)	0.002	0.998	0.000
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.002	0.998	0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.998	0.002
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.998	0.002
Y53.7 Emetics	0.000	0.998	0.002
Y53.6 Antidiarrhoeal drugs	0.000	0.998	0.002
Y53.5 Digestants	0.000	0.998	0.002
Y53.3 Saline and osmotic laxatives	0.000	0.998	0.002
Y53.2 Stimulant laxatives	0.000	0.998	0.002
Y53.0 Histamine H2-receptor antagonists	0.000	0.998	0.002
N92.1 Excessive and frequent menstruation with irregular cycle	0.000	0.998	0.002
K50.1 Crohn's disease of large intestine	0.000	0.998	0.002
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.000	0.998	0.002
O16 Unspecified maternal hypertension	0.002	0.998	0.000
M89.84 Other specified disorders of bone (Hand)	0.002	0.998	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
Y49.2 Other and unspecified antidepressants	0.000	0.998	0.002
M89.39 Hypertrophy of bone (Site unspecified)	0.002	0.998	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.002	0.998	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.002	0.998	0.000
M89.34 Hypertrophy of bone (Hand)	0.002	0.998	0.000
M89.33 Hypertrophy of bone (Forearm)	0.002	0.998	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.002	0.998	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.002	0.998	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.002	0.998	0.000
Y57.6 Other diagnostic agents	0.000	0.998	0.002
E66.8 Other obesity	0.000	0.998	0.002
Y45.5 4-Aminophenol derivatives	0.000	0.998	0.002
Z83 Family history of other specific disorders	0.002	0.998	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.002	0.998	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.002	0.998	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.002	0.998	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.002	0.998	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.002	0.998	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.002	0.998	0.000
Y52.1 Calcium-channel blockers	0.000	0.998	0.002
Y57.7 Vitamins, not elsewhere classified	0.000	0.998	0.002
Y57.4 Pharmaceutical excipients	0.000	0.998	0.002
Y57.3 Alcohol deterrents	0.000	0.998	0.002
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.000	0.998	0.002
Y57.1 Lipotropic drugs	0.000	0.998	0.002
Y57.0 Appetite depressants [anorectics]	0.000	0.998	0.002
M46 Other inflammatory spondylopathies	0.002	0.998	0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.000	0.998	0.002
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.002	0.998	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.000	0.998	0.002
M95.2 Other acquired deformity of head	0.002	0.998	0.000
Y53.4 Other laxatives	0.000	0.998	0.002
M87 Osteonecrosis	0.002	0.998	0.000
M87.9 Osteonecrosis, unspecified	0.002	0.998	0.000
Y41.5 Antiviral drugs	0.000	0.998	0.002
M90.78 Fracture of bone in neoplastic disease (Other)	0.002	0.998	0.000
M90.8 Osteopathy in other diseases classified elsewhere	0.002	0.998	0.000
M90.6 Osteitis deformans in neoplastic disease	0.002	0.998	0.000
M90.5 Osteonecrosis in other diseases classified elsewhere	0.002	0.998	0.000
M90.4 Osteonecrosis due to heamoglobinopathy	0.002	0.998	0.000
M90.3 Osteonecrosis in caisson disease	0.002	0.998	0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere	0.002	0.998	0.000
M90.1 Periostitis in other infectious diseases classified elsewhere	0.002	0.998	0.000
M90.0 Tuberculosis of bone	0.002	0.998	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.002	0.998	0.000
M89.83 Other specified disorders of bone (Forearm)	0.002	0.998	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.002	0.998	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.002	0.998	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
K35.3 Acute appendicitis with localized peritonitis	0.002	0.998	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.000	0.998	0.002
O14.0 Moderate preeclampsia	0.002	0.998	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.002	0.998	0.000
Y45.4 Antirheumatics	0.000	0.998	0.002
K50.8 Other Crohn's disease	0.000	0.998	0.002
Y52.4 Angiotensin-converting-enzyme inhibitors	0.000	0.998	0.002
M88 Paget's disease of bone [osteitis deformans]	0.002	0.998	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.002	0.998	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.002	0.998	0.000
N87.1 Moderate cervical dysplasia	0.002	0.998	0.000
M89.19 Epiphyseal arrest (Site unspecified)	0.002	0.998	0.000
M89.18 Epiphyseal arrest (Other)	0.002	0.998	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.002	0.998	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.002	0.998	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.002	0.998	0.000
M89.14 Epiphyseal arrest (Hand)	0.002	0.998	0.000
M89.13 Epiphyseal arrest (Forearm)	0.002	0.998	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.002	0.998	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.002	0.998	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.002	0.998	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.002	0.998	0.000
M89.28 Other disorders of bone development and growth (Other)	0.002	0.998	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.002	0.998	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.002	0.998	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.002	0.998	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.002	0.998	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.002	0.998	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.002	0.998	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.002	0.998	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.002	0.998	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.002	0.998	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.002	0.998	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.002	0.998	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.002	0.998	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.002	0.998	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.002	0.998	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.002	0.998	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.002	0.998	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.002	0.998	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.002	0.998	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.002	0.998	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.002	0.998	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.002	0.998	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.002	0.998	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.002	0.998	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.002	0.998	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.002	0.998	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.002	0.998	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.002	0.998	0.000
M89.9 Disorder of bone, unspecified	0.002	0.998	0.000
O21.0 Mild hyperemesis gravidarum	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.998	0.002
Y53.1 Other antacids and anti-gastric-secretion drugs	0.000	0.998	0.002
M89.59 Osteolysis (Site unspecified)	0.002	0.998	0.000
M89.58 Osteolysis (Other)	0.002	0.998	0.000
M89.57 Osteolysis (Ankle and foot)	0.002	0.998	0.000
M89.56 Osteolysis (Lower leg)	0.002	0.998	0.000
M89.54 Osteolysis (Hand)	0.002	0.998	0.000
M89.53 Osteolysis (Forearm)	0.002	0.998	0.000
M89.52 Osteolysis (Upper arm)	0.002	0.998	0.000
M89.51 Osteolysis (Shoulder region)	0.002	0.998	0.000
M89.50 Osteolysis (Multiple sites)	0.002	0.998	0.000
Y45.8 Other analgesics and antipyretics	0.000	0.998	0.002
Y55.6 Antiasthmatics, not elsewhere classified	0.001	0.998	0.002
Z83.6 Family history of diseases of the respiratory system	0.002	0.998	0.000
Y43 Primarily systemic agents	0.000	0.998	0.002
M89.55 Osteolysis (Pelvic region and thigh)	0.002	0.998	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.002	0.998	0.001
Y59.3 Immunoglobulin	0.000	0.998	0.002
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.002	0.998	0.000
C18.7 Sigmoid colon	0.002	0.998	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.000	0.998	0.002
M86 Osteomyelitis	0.002	0.998	0.000
K43.0 Ventral hernia with obstruction, without gangrene	0.000	0.998	0.002
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.998	0.002
Y43.1 Antineoplastic antimetabolites	0.000	0.998	0.002
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.002	0.998	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.002	0.998	0.000
Y45.1 Salicylates	0.000	0.998	0.002
Y57.5 X-ray contrast media	0.000	0.998	0.002
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.002	0.998	0.000
D33.3 Cranial nerves	0.002	0.998	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.002	0.998	0.000
I27 Other pulmonary heart diseases	0.002	0.998	0.000
N87 Dysplasia of cervix uteri	0.002	0.998	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.002	0.998	0.000
C90.2 Plasmacytoma, extramedullary	0.000	0.998	0.002
I27.9 Pulmonary heart disease, unspecified	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.998	0.002
I27.8 Other specified pulmonary heart diseases	0.002	0.998	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.002	0.998	0.000
Z83.0 Family history of human immunodeficiency virus [HIV]	0.002	0.998	0.000
M46.8 Other specified inflammatory spondylopathies	0.002	0.998	0.000
M46.5 Other infective spondylopathies	0.002	0.998	0.000
M46.2 Osteomyelitis of vertebra	0.002	0.998	0.000
M46.0 Spinal enthesopathy	0.002	0.998	0.000
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens	0.002	0.998	0.000
R48.8 Other and unspecified symbolic dysfunctions	0.000	0.998	0.002
R48.2 Apraxia	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations