TreeWAS – Variant ID: rs11014306

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.5 Disorders of calcium metabolism	0.015	0.985	0.000
K76.8 Other specified diseases of liver	0.000	0.986	0.014
E83 Disorders of mineral metabolism	0.013	0.987	0.000
E83.4 Disorders of magnesium metabolism	0.013	0.987	0.000
N13.3 Other and unspecified hydronephrosis	0.012	0.988	0.000
E83.1 Disorders of iron metabolism	0.012	0.988	0.000
W19.9 Unspecified place	0.000	0.988	0.012
E83.9 Disorder of mineral metabolism, unspecified	0.009	0.990	0.000
E83.8 Other disorders of mineral metabolism	0.009	0.990	0.000
E83.2 Disorders of zinc metabolism	0.009	0.990	0.000
E83.0 Disorders of copper metabolism	0.009	0.990	0.000
G51.0 Bell's palsy	0.009	0.991	0.000
N18.5 Chronic kidney disease, stage 5	0.009	0.991	0.000
E83.3 Disorders of phosphorus metabolism	0.009	0.991	0.000
N13 Obstructive and reflux uropathy	0.008	0.992	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.008	0.992	0.000
N13.4 Hydroureter	0.007	0.993	0.000
H20 Iridocyclitis	0.007	0.993	0.000
H20.0 Acute and subacute iridocyclitis	0.007	0.993	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.007	0.993	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.007	0.993	0.000
H20.9 Iridocyclitis, unspecified	0.007	0.993	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.007	0.993	0.000
N13.6 Pyonephrosis	0.006	0.993	0.000
H20.8 Other iridocyclitis	0.006	0.994	0.000
H20.1 Chronic iridocyclitis	0.006	0.994	0.000
R16.1 Splenomegaly, not elsewhere classified	0.006	0.994	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.006	0.994	0.000
H20.2 Lens-induced iridocyclitis	0.005	0.994	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.005	0.994	0.000
H16 Keratitis	0.005	0.995	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.005	0.995	0.000
H16.0 Corneal ulcer	0.005	0.995	0.000
N13.8 Other obstructive and reflux uropathy	0.005	0.995	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.005	0.995	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.005	0.995	0.000
S01.9 Open wound of head, part unspecified	0.005	0.995	0.000
Q65.8 Other congenital deformities of hip	0.005	0.995	0.000
H15 Disorders of sclera	0.004	0.995	0.000
H18 Other disorders of cornea	0.004	0.996	0.000
H17 Corneal scars and opacities	0.004	0.996	0.000
H16.9 Keratitis, unspecified	0.004	0.996	0.000
G51 Facial nerve disorders	0.004	0.996	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.004	0.996	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.004	0.996	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.004	0.996	0.000
H21 Other disorders of iris and ciliary body	0.004	0.996	0.000
H16.8 Other keratitis	0.004	0.996	0.000
H16.4 Corneal neovascularisation	0.004	0.996	0.000
H16.3 Interstitial and deep keratitis	0.004	0.996	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.004	0.996	0.000
N17.9 Acute renal failure, unspecified	0.004	0.996	0.000
H16.2 Keratoconjunctivitis	0.004	0.996	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.004	0.996	0.000
Q65 Congenital deformities of hip	0.004	0.996	0.000
H18.2 Other corneal oedema	0.004	0.996	0.000
H18.8 Other specified disorders of cornea	0.004	0.996	0.000
N10-N16 Renal tubulo-interstitial diseases	0.004	0.996	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.004	0.996	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
H18.1 Bullous keratopathy	0.004	0.996	0.000
G51.9 Disorder of facial nerve, unspecified	0.004	0.996	0.000
H18.4 Corneal degeneration	0.003	0.996	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.004	0.996	0.000
C77.1 Intrathoracic lymph nodes	0.004	0.996	0.000
S92.00 Fracture of calcaneus (closed)	0.000	0.996	0.003
H15.9 Disorder of sclera, unspecified	0.003	0.996	0.000
H15.8 Other disorders of sclera	0.003	0.996	0.000
H15.1 Episcleritis	0.003	0.996	0.000
H15.0 Scleritis	0.003	0.996	0.000
M47.82 Other spondylosis (Cervical region)	0.000	0.997	0.003
H18.7 Other corneal deformities	0.003	0.997	0.000
H18.3 Changes in corneal membranes	0.003	0.997	0.000
H18.0 Corneal pigmentations and deposits	0.003	0.997	0.000
H17.8 Other corneal scars and opacities	0.003	0.997	0.000
H17.1 Other central corneal opacity	0.003	0.997	0.000
H17.0 Adherent leukoma	0.003	0.997	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.003	0.997	0.000
H21.8 Other specified disorders of iris and ciliary body	0.003	0.997	0.000
M54.36 Sciatica (Lumbar region)	0.003	0.997	0.000
N11 Chronic tubulo-interstitial nephritis	0.003	0.997	0.000
G51.8 Other disorders of facial nerve	0.003	0.997	0.000
G51.4 Facial myokymia	0.003	0.997	0.000
G51.2 Melkersson's syndrome	0.003	0.997	0.000
G51.1 Geniculate ganglionitis	0.003	0.997	0.000
H17.9 Corneal scar and opacity, unspecified	0.003	0.997	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.003	0.997	0.000
H21.4 Pupillary membranes	0.003	0.997	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.003	0.997	0.000
H21.2 Degeneration of iris and ciliary body	0.003	0.997	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.003	0.997	0.000
H21.0 Hyphaema	0.003	0.997	0.000
H18.9 Disorder of cornea, unspecified	0.003	0.997	0.000
J32.9 Chronic sinusitis, unspecified	0.000	0.997	0.003
Q28.2 Arteriovenous malformation of cerebral vessels	0.003	0.997	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.003	0.997	0.000
Q76 Congenital malformations of spine and bony thorax	0.003	0.997	0.000
Q65.9 Congenital deformity of hip, unspecified	0.003	0.997	0.000
Q65.6 Unstable hip	0.003	0.997	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.003	0.997	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.003	0.997	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.003	0.997	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.003	0.997	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.003	0.997	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.003	0.997	0.000
Q28 Other congenital malformations of circulatory system	0.003	0.997	0.000
Q74 Other congenital malformations of limb(s)	0.003	0.997	0.000
G51.3 Clonic hemifacial spasm	0.003	0.997	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.003	0.997	0.000
N15 Other renal tubulo-interstitial diseases	0.003	0.997	0.000
D61.9 Aplastic anaemia, unspecified	0.003	0.997	0.000
L29.0 Pruritus ani	0.000	0.997	0.003
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.003	0.997	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.003	0.997	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.003	0.997	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.003	0.997	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.003	0.997	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.003	0.997	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.003	0.997	0.000
Q78 Other osteochondrodysplasias	0.003	0.997	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
Q75 Other congenital malformations of skull and face bones	0.003	0.997	0.000
Q73 Reduction defects of unspecified limb	0.003	0.997	0.000
Q72 Reduction defects of lower limb	0.003	0.997	0.000
Q71 Reduction defects of upper limb	0.003	0.997	0.000
Q70 Syndactyly	0.003	0.997	0.000
Q69 Polydactyly	0.003	0.997	0.000
Q68 Other congenital musculoskeletal deformities	0.003	0.997	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.003	0.997	0.000
S92.0 Fracture of calcaneus	0.000	0.997	0.003
N17 Acute renal failure	0.003	0.997	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.003	0.997	0.000
N14.3 Nephropathy induced by heavy metals	0.003	0.997	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.003	0.997	0.000
N14.0 Analgesic nephropathy	0.003	0.997	0.000
H18.5 Hereditary corneal dystrophies	0.003	0.997	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.003	0.997	0.000
N11.1 Chronic obstructive pyelonephritis	0.003	0.997	0.000
V49.9 Car occupant [any] injured in unspecified traffic accident	0.003	0.997	0.000
Q66 Congenital deformities of feet	0.003	0.997	0.000
Q24 Other congenital malformations of heart	0.003	0.997	0.000
Q60-Q64 Congenital malformations of the urinary system	0.003	0.997	0.000
I08.0 Disorders of both mitral and aortic valves	0.000	0.997	0.003
Q76.0 Spina bifida occulta	0.002	0.997	0.000
H04.2 Epiphora	0.003	0.997	0.000
Q50-Q56 Congenital malformations of genital organs	0.003	0.997	0.000
Q51 Congenital malformations of uterus and cervix	0.002	0.997	0.000
Q74.1 Congenital malformation of knee	0.002	0.997	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.002	0.997	0.000
Q76.8 Other congenital malformations of bony thorax	0.002	0.997	0.000
Q76.7 Congenital malformation of sternum	0.002	0.997	0.000
Q76.6 Other congenital malformations of ribs	0.002	0.997	0.000
Q76.5 Cervical rib	0.002	0.997	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.002	0.997	0.000
Q76.2 Congenital spondylolisthesis	0.002	0.997	0.000
Q76.1 Klippel-Feil syndrome	0.002	0.997	0.000
Q25 Congenital malformations of great arteries	0.002	0.997	0.000
N17.0 Acute renal failure with tubular necrosis	0.002	0.997	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.002	0.997	0.000
N10 Acute tubulo-interstitial nephritis	0.002	0.997	0.000
Q51.2 Other doubling of uterus	0.002	0.998	0.000
Q61 Cystic kidney disease	0.002	0.998	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998	0.000
Q24.8 Other specified congenital malformations of heart	0.002	0.998	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.002	0.998	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.002	0.998	0.000
Q28.3 Other malformations of cerebral vessels	0.002	0.998	0.000
Q28.1 Other malformations of precerebral vessels	0.002	0.998	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.002	0.998	0.000
Q61.3 Polycystic kidney, unspecified	0.002	0.998	0.000
M81.98 Osteoporosis, unspecified (Other)	0.000	0.998	0.002
Q74.9 Unspecified congenital malformation of limb(s)	0.002	0.998	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.002	0.998	0.000
Q74.3 Arthrogryposis multiplex congenita	0.002	0.998	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.002	0.998	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.002	0.998	0.000
N15.8 Other specified renal tubulo-interstitial diseases	0.002	0.998	0.000
N15.1 Renal and perinephric abscess	0.002	0.998	0.000
N15.0 Balkan nephropathy	0.002	0.998	0.000
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.002	0.998	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.002	0.998	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.002	0.998	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.002	0.998	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.002	0.998	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.002	0.998	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.002	0.998	0.000
Q44.6 Cystic disease of liver	0.002	0.998	0.000
Q26 Congenital malformations of great veins	0.002	0.998	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.002	0.998	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.002	0.998	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.002	0.998	0.000
Q66.3 Other congenital varus deformities of feet	0.002	0.998	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.002	0.998	0.000
Q27 Other congenital malformations of peripheral vascular system	0.002	0.998	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.002	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998	0.000
H18.6 Keratoconus	0.002	0.998	0.001
N17.8 Other acute renal failure	0.002	0.998	0.000
Q79.6 Ehlers-Danlos syndrome	0.002	0.998	0.000
Q52 Other congenital malformations of female genitalia	0.002	0.998	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.998	0.002
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.002	0.998	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.002	0.998	0.000
Q79.5 Other congenital malformations of abdominal wall	0.002	0.998	0.000
Q79.4 Prune belly syndrome	0.002	0.998	0.000
Q79.3 Gastroschisis	0.002	0.998	0.000
Q79.2 Exomphalos	0.002	0.998	0.000
Q79.1 Other congenital malformations of diaphragm	0.002	0.998	0.000
Q79.0 Congenital diaphragmatic hernia	0.002	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.002	0.998	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.998	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.002	0.998	0.000
Q67.8 Other congenital deformities of chest	0.002	0.998	0.000
Q67.7 Pectus carinatum	0.002	0.998	0.000
Q67.6 Pectus excavatum	0.002	0.998	0.000
Q67.5 Congenital deformity of spine	0.002	0.998	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.002	0.998	0.000
Q67.3 Plagiocephaly	0.002	0.998	0.000
Q67.2 Dolichocephaly	0.002	0.998	0.000
Q67.1 Compression facies	0.002	0.998	0.000
Q67.0 Facial asymmetry	0.002	0.998	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.002	0.998	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.002	0.998	0.000
Q68.4 Congenital bowing of tibia and fibula	0.002	0.998	0.000
Q68.3 Congenital bowing of femur	0.002	0.998	0.000
Q68.2 Congenital deformity of knee	0.002	0.998	0.000
Q68.1 Congenital deformity of hand	0.002	0.998	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.002	0.998	0.000
Q69.9 Polydactyly, unspecified	0.002	0.998	0.000
Q69.2 Accessory toe(s)	0.002	0.998	0.000
Q69.1 Accessory thumb(s)	0.002	0.998	0.000
Q69.0 Accessory finger(s)	0.002	0.998	0.000
Q70.9 Syndactyly, unspecified	0.002	0.998	0.000
Q70.4 Polysyndactyly	0.002	0.998	0.000
Q70.3 Webbed toes	0.002	0.998	0.000
Q70.2 Fused toes	0.002	0.998	0.000
Q70.1 Webbed fingers	0.002	0.998	0.000
Q70.0 Fused fingers	0.002	0.998	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.002	0.998	0.000
Q71.8 Other reduction defects of upper limb(s)	0.002	0.998	0.000
Q71.6 Lobster-claw hand	0.002	0.998	0.000
Q71.5 Longitudinal reduction defect of ulna	0.002	0.998	0.000
Q71.4 Longitudinal reduction defect of radius	0.002	0.998	0.000
Q71.3 Congenital absence of hand and finger(s)	0.002	0.998	0.000
Q71.2 Congenital absence of both forearm and hand	0.002	0.998	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.002	0.998	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.002	0.998	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.002	0.998	0.000
Q72.8 Other reduction defects of lower limb(s)	0.002	0.998	0.000
Q72.7 Split foot	0.002	0.998	0.000
Q72.6 Longitudinal reduction defect of fibula	0.002	0.998	0.000
Q72.5 Longitudinal reduction defect of tibia	0.002	0.998	0.000
Q72.4 Longitudinal reduction defect of femur	0.002	0.998	0.000
Q72.3 Congenital absence of foot and toe(s)	0.002	0.998	0.000
Q72.2 Congenital absence of both lower leg and foot	0.002	0.998	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.002	0.998	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.002	0.998	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.002	0.998	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.002	0.998	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.002	0.998	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.002	0.998	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.002	0.998	0.000
Q75.5 Oculomandibular dysostosis	0.002	0.998	0.000
Q75.4 Mandibulofacial dysostosis	0.002	0.998	0.000
Q75.3 Macrocephaly	0.002	0.998	0.000
Q75.2 Hypertelorism	0.002	0.998	0.000
Q75.1 Craniofacial dysostosis	0.002	0.998	0.000
Q75.0 Craniosynostosis	0.002	0.998	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.002	0.998	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.002	0.998	0.000
Q77.6 Chondroectodermal dysplasia	0.002	0.998	0.000
Q77.5 Diastrophic dysplasia	0.002	0.998	0.000
Q77.4 Achondroplasia	0.002	0.998	0.000
Q77.3 Chondrodysplasia punctata	0.002	0.998	0.000
Q77.2 Short rib syndrome	0.002	0.998	0.000
Q77.1 Thanatophoric short stature	0.002	0.998	0.000
Q77.0 Achondrogenesis	0.002	0.998	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.002	0.998	0.000
Q78.8 Other specified osteochondrodysplasias	0.002	0.998	0.000
Q78.6 Multiple congenital exostoses	0.002	0.998	0.000
Q78.5 Metaphyseal dysplasia	0.002	0.998	0.000
Q78.4 Enchondromatosis	0.002	0.998	0.000
Q78.3 Progressive diaphyseal dysplasia	0.002	0.998	0.000
Q78.2 Osteopetrosis	0.002	0.998	0.000
Q78.1 Polyostotic fibrous dysplasia	0.002	0.998	0.000
Q78.0 Osteogenesis imperfecta	0.002	0.998	0.000
S92.01 Fracture of calcaneus (open)	0.000	0.998	0.002
Q24.5 Malformation of coronary vessels	0.002	0.998	0.000
N17.2 Acute renal failure with medullary necrosis	0.002	0.998	0.000
N17.1 Acute renal failure with acute cortical necrosis	0.002	0.998	0.000
Q25.0 Patent ductus arteriosus	0.002	0.998	0.000
Q61.2 Polycystic kidney, adult type	0.002	0.998	0.000
Q51.3 Bicornate uterus	0.002	0.998	0.000
L29.9 Pruritus, unspecified	0.000	0.998	0.002
S92 Fracture of foot, except ankle	0.000	0.998	0.002
Q12 Congenital lens malformations	0.002	0.998	0.000
Q66.9 Congenital deformity of feet, unspecified	0.002	0.998	0.000
Q66.7 Pes cavus	0.002	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.002	0.998	0.000
Q66.5 Congenital pes planus	0.002	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.002	0.998	0.000
Q66.2 Metatarsus varus	0.002	0.998	0.000
Q66.1 Talipes calcaneovarus	0.002	0.998	0.000
Q66.0 Talipes equinovarus	0.002	0.998	0.000
Q24.6 Congenital heart block	0.002	0.998	0.000
Q24.4 Congenital subaortic stenosis	0.002	0.998	0.000
Q24.3 Pulmonary infundibular stenosis	0.002	0.998	0.000
Q24.2 Cor triatriatum	0.002	0.998	0.000
Q24.1 Levocardia	0.002	0.998	0.000
Q24.0 Dextrocardia	0.002	0.998	0.000
M54.3 Sciatica	0.002	0.998	0.000
Q64 Other congenital malformations of urinary system	0.002	0.998	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
Q52.5 Fusion of labia	0.002	0.998	0.000
Q60.2 Renal agenesis, unspecified	0.002	0.998	0.000
Q14 Congenital malformations of posterior segment of eye	0.002	0.998	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.002	0.998	0.000
L29 Pruritus	0.000	0.998	0.002
Q23 Congenital malformations of aortic and mitral valves	0.002	0.998	0.000
Q21 Congenital malformations of cardiac septa	0.002	0.998	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.002	0.998	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.002	0.998	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.002	0.998	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.002	0.998	0.000
Q51.6 Embryonic cyst of cervix	0.002	0.998	0.000
Q51.5 Agenesis and aplasia of cervix	0.002	0.998	0.000
Q51.4 Unicornate uterus	0.002	0.998	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.002	0.998	0.000
Q51.0 Agenesis and aplasia of uterus	0.002	0.998	0.000
S92.3 Fracture of metatarsal bone	0.000	0.998	0.002
Q56 Indeterminate sex and pseudohermaphroditism	0.002	0.998	0.000
Q55 Other congenital malformations of male genital organs	0.002	0.998	0.000
Q12.0 Congenital cataract	0.002	0.998	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.002	0.998	0.000
Q25.8 Other congenital malformations of great arteries	0.002	0.998	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.002	0.998	0.000
Q25.6 Stenosis of pulmonary artery	0.002	0.998	0.000
Q25.5 Atresia of pulmonary artery	0.002	0.998	0.000
Q25.4 Other congenital malformations of aorta	0.002	0.998	0.000
Q25.3 Stenosis of aorta	0.002	0.998	0.000
Q25.2 Atresia of aorta	0.002	0.998	0.000
Q25.1 Coarctation of aorta	0.002	0.998	0.000
Q61.5 Medullary cystic kidney	0.002	0.998	0.000
U89.8 Agent resistant to other single specified antibiotic	0.002	0.998	0.000
M81.9 Osteoporosis, unspecified	0.000	0.998	0.002
Q53 Undescended testicle	0.002	0.998	0.000
Q21.0 Ventricular septal defect	0.002	0.998	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.002	0.998	0.000
Q39 Congenital malformations of oesophagus	0.002	0.998	0.000
S92.30 Fracture of metatarsal bone (closed)	0.000	0.998	0.002
Q61.9 Cystic kidney disease, unspecified	0.002	0.998	0.000
Q61.8 Other cystic kidney diseases	0.002	0.998	0.000
Q61.4 Renal dysplasia	0.002	0.998	0.000
Q61.1 Polycystic kidney, infantile type	0.002	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.000	0.998	0.002
C77.9 Lymph node, unspecified	0.002	0.998	0.000
Q17 Other congenital malformations of ear	0.002	0.998	0.000
Q45 Other congenital malformations of digestive system	0.002	0.998	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.002	0.998	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.002	0.998	0.000
Q40 Other congenital malformations of upper alimentary tract	0.002	0.998	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.998	0.002
Q16 Congenital malformations of ear causing impairment of hearing	0.002	0.998	0.000
Q15 Other congenital malformations of eye	0.002	0.998	0.000
Q13 Congenital malformations of anterior segment of eye	0.002	0.998	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.002	0.998	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.002	0.998	0.000
Q63 Other congenital malformations of kidney	0.002	0.998	0.000
Q96 Turner's syndrome	0.002	0.998	0.000
Q00-Q07 Congenital malformations of the nervous system	0.002	0.998	0.000
M54.37 Sciatica (Lumbosacral region)	0.002	0.998	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.998	0.002
Q14.1 Congenital malformation of retina	0.002	0.998	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.002	0.998	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.002	0.998	0.000
Q20.6 Isomerism of atrial appendages	0.002	0.998	0.000
Q20.5 Discordant atrioventricular connexion	0.002	0.998	0.000
Q20.4 Double inlet ventricle	0.002	0.998	0.000
Q20.3 Discordant ventriculoarterial connexion	0.002	0.998	0.000
Q20.2 Double outlet left ventricle	0.002	0.998	0.000
Q20.1 Double outlet right ventricle	0.002	0.998	0.000
Q20.0 Common arterial trunk	0.002	0.998	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.002	0.998	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.002	0.998	0.000
Q22.6 Hypoplastic right heart syndrome	0.002	0.998	0.000
Q22.5 Ebstein's anomaly	0.002	0.998	0.000
Q22.4 Congenital tricuspid stenosis	0.002	0.998	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.002	0.998	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.002	0.998	0.000
Q22.1 Congenital pulmonary valve stenosis	0.002	0.998	0.000
Q22.0 Pulmonary valve atresia	0.002	0.998	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.002	0.998	0.000
Q26.8 Other congenital malformations of great veins	0.002	0.998	0.000
Q26.6 Portal vein-hepatic artery fistula	0.002	0.998	0.000
Q26.5 Anomalous portal venous connexion	0.002	0.998	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.002	0.998	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.002	0.998	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.002	0.998	0.000
Q26.1 Persistent left superior vena cava	0.002	0.998	0.000
Q26.0 Congenital stenosis of vena cava	0.002	0.998	0.000
Q44.7 Other congenital malformations of liver	0.002	0.998	0.000
Q44.5 Other congenital malformations of bile ducts	0.002	0.998	0.000
Q44.4 Choledochal cyst	0.002	0.998	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.002	0.998	0.000
Q44.2 Atresia of bile ducts	0.002	0.998	0.000
Q44.1 Other congenital malformations of gallbladder	0.002	0.998	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.002	0.998	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.002	0.998	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.002	0.998	0.000
Q27.4 Congenital phlebectasia	0.002	0.998	0.000
Q27.2 Other congenital malformations of renal artery	0.002	0.998	0.000
Q27.1 Congenital renal artery stenosis	0.002	0.998	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.002	0.998	0.000
Q60.6 Potter's syndrome	0.002	0.998	0.000
Q60.5 Renal hypoplasia, unspecified	0.002	0.998	0.000
Q60.4 Renal hypoplasia, bilateral	0.002	0.998	0.000
Q60.3 Renal hypoplasia, unilateral	0.002	0.998	0.000
Q60.1 Renal agenesis, bilateral	0.002	0.998	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.002	0.998	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.002	0.998	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.002	0.998	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.002	0.998	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.002	0.998	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.002	0.998	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.002	0.998	0.000
Q90 Down's syndrome	0.002	0.998	0.000
Q60.0 Renal agenesis, unilateral	0.002	0.998	0.000
S92.4 Fracture of great toe	0.000	0.998	0.002
Q38 Other congenital malformations of tongue, mouth and pharynx	0.002	0.998	0.000
Q54 Hypospadias	0.002	0.998	0.000
Q80-Q89 Other congenital malformations	0.002	0.998	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.998	0.002
Q52.9 Congenital malformation of female genitalia, unspecified	0.002	0.998	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.002	0.998	0.000
Q52.7 Other congenital malformations of vulva	0.002	0.998	0.000
Q52.6 Congenital malformation of clitoris	0.002	0.998	0.000
Q52.4 Other congenital malformations of vagina	0.002	0.998	0.000
Q52.3 Imperforate hymen	0.002	0.998	0.000
Q52.2 Congenital rectovaginal fistula	0.002	0.998	0.000
Q52.1 Doubling of vagina	0.002	0.998	0.000
Q52.0 Congenital absence of vagina	0.002	0.998	0.000
Q34 Other congenital malformations of respiratory system	0.002	0.998	0.000
Q33 Congenital malformations of lung	0.002	0.998	0.000
Q32 Congenital malformations of trachea and bronchus	0.002	0.998	0.000
Q31 Congenital malformations of larynx	0.002	0.998	0.000
Q30 Congenital malformations of nose	0.002	0.998	0.000
Q37 Cleft palate with cleft lip	0.002	0.998	0.000
Q36 Cleft lip	0.002	0.998	0.000
Q35 Cleft palate	0.002	0.998	0.000
Q27.3 Peripheral arteriovenous malformation	0.002	0.998	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.002	0.998	0.000
L29.8 Other pruritus	0.000	0.998	0.002
S92.9 Fracture of foot, unspecified	0.000	0.998	0.002
S92.7 Multiple fractures of foot	0.000	0.998	0.002
Q12.9 Congenital lens malformation, unspecified	0.002	0.998	0.000
Q12.8 Other congenital lens malformations	0.002	0.998	0.000
Q12.4 Spherophakia	0.002	0.998	0.000
Q12.3 Congenital aphakia	0.002	0.998	0.000
Q12.2 Coloboma of lens	0.002	0.998	0.000
Q12.1 Congenital displaced lens	0.002	0.998	0.000
S92.1 Fracture of talus	0.000	0.998	0.002
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.002	0.998	0.000
M54.35 Sciatica (Thoracolumbar region)	0.002	0.998	0.000
M54.34 Sciatica-Thoracic	0.002	0.998	0.000
M54.33 Sciatica-Cervicothoracic	0.002	0.998	0.000
M54.32 Sciatica-Cervical	0.002	0.998	0.000
M54.31 Sciatica-Occipit-atl-axl	0.002	0.998	0.000
M54.30 Sciatica (Multiple sites in spine)	0.002	0.998	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.000	0.998	0.002
Q14.9 Congenital malformation of posterior segment of eye, unspecified	0.002	0.998	0.000
Q14.8 Other congenital malformations of posterior segment of eye	0.002	0.998	0.000
Q14.3 Congenital malformation of choroid	0.002	0.998	0.000
Q14.2 Congenital malformation of optic disk	0.002	0.998	0.000
Q14.0 Congenital malformation of vitreous humour	0.002	0.998	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.002	0.998	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.002	0.998	0.000
Q64.8 Other specified congenital malformations of urinary system	0.002	0.998	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.002	0.998	0.000
Q64.6 Congenital diverticulum of bladder	0.002	0.998	0.000
Q64.5 Congenital absence of bladder and urethra	0.002	0.998	0.000
Q64.4 Malformation of urachus	0.002	0.998	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.002	0.998	0.000
Q64.2 Congenital posterior urethral valves	0.002	0.998	0.000
Q64.1 Exstrophy of urinary bladder	0.002	0.998	0.000
Q64.0 Epispadias	0.002	0.998	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.998	0.000
Q62.8 Other congenital malformations of ureter	0.002	0.998	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.002	0.998	0.000
Q62.6 Malposition of ureter	0.002	0.998	0.000
Q62.4 Agenesis of ureter	0.002	0.998	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.002	0.998	0.000
Q62.2 Congenital megaloureter	0.002	0.998	0.000
Q62.1 Atresia and stenosis of ureter	0.002	0.998	0.000
Q62.0 Congenital hydronephrosis	0.002	0.998	0.000
L29.3 Anogenital pruritus, unspecified	0.000	0.998	0.002
L29.1 Pruritus scroti	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations