TreeWAS – Variant ID: rs11022756

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N81.3 Complete uterovaginal prolapse	0.447	0.553	0.000
I10 Essential (primary) hypertension	0.364	0.636	0.000
I10-I15 Hypertensive diseases	0.342	0.658	0.000
I12 Hypertensive renal disease	0.338	0.662	0.000
I12.0 Hypertensive renal disease with renal failure	0.338	0.662	0.000
I15 Secondary hypertension	0.293	0.707	0.000
I15.9 Seconday hypertension, unspecified	0.247	0.753	0.000
I15.1 Hypertension secondary to other renal disorders	0.240	0.760	0.000
I12.9 Hypertensive renal disease without renal failure	0.231	0.769	0.000
I11 Hypertensive heart disease	0.227	0.773	0.000
I15.0 Renovascular hypertension	0.215	0.785	0.000
I13 Hypertensive heart and renal disease	0.213	0.787	0.000
I15.8 Other secondary hypertension	0.213	0.787	0.000
I15.2 Hypertension secondary to endocrine disorders	0.187	0.813	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.180	0.820	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.153	0.847	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.152	0.848	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.146	0.854	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.132	0.867	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.114	0.886	0.000
C67.6 Ureteric orifice	0.072	0.928	0.000
C67 Malignant neoplasm of bladder	0.072	0.928	0.000
C67.1 Dome of bladder	0.066	0.934	0.000
C67.3 Anterior wall of bladder	0.066	0.934	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.062	0.938	0.000
C67.2 Lateral wall of bladder	0.062	0.938	0.000
C67.5 Bladder neck	0.062	0.938	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.061	0.939	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.061	0.939	0.000
Y45.0 Opioids and related analgesics	0.059	0.941	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.057	0.943	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.056	0.944	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.055	0.945	0.000
Y52 Agents primarily affecting the cardiovascular system	0.054	0.946	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.054	0.946	0.000
C67.8 Overlapping lesion of bladder	0.052	0.948	0.000
C67.7 Urachus	0.051	0.948	0.000
Y48 Anaesthetics and therapeutic gases	0.050	0.950	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.050	0.950	0.000
Y45.1 Salicylates	0.049	0.950	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.049	0.951	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.048	0.952	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.048	0.952	0.000
Y45.5 4-Aminophenol derivatives	0.048	0.952	0.000
Y45.2 Propionic acid derivatives	0.047	0.953	0.000
Y45.8 Other analgesics and antipyretics	0.047	0.953	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.047	0.953	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.047	0.953	0.000
Y45.4 Antirheumatics	0.047	0.953	0.000
C67.0 Trigone of bladder	0.046	0.954	0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.046	0.954	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.046	0.954	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.046	0.954	0.000
Y48.3 Local anaesthetics	0.046	0.954	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.045	0.955	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.045	0.955	0.000
C67.9 Bladder, unspecified	0.045	0.955	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.044	0.956	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.044	0.956	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.044	0.956	0.000
C64-C68 Malignant neoplasms of urinary tract	0.043	0.957	0.000
C67.4 Posterior wall of bladder	0.043	0.957	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.043	0.957	0.000
Y52.1 Calcium-channel blockers	0.043	0.957	0.000
Y49.5 Other antipsychotics and neuroleptics	0.043	0.957	0.000
Y52.7 Peripheral vasodilators	0.042	0.958	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.041	0.959	0.000
Y54.5 Other diuretics	0.041	0.959	0.000
Y48.2 Other and unspecified general anaesthetics	0.041	0.959	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.041	0.959	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.040	0.960	0.000
C66 Malignant neoplasm of ureter	0.040	0.960	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.040	0.960	0.000
Y58 Bacterial vaccines	0.039	0.960	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.039	0.961	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.039	0.961	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.038	0.962	0.000
Y59 Other and unspecified vaccines and biological substances	0.037	0.963	0.000
Y48.4 Anaesthetic, unspecified	0.037	0.963	0.000
Y53.2 Stimulant laxatives	0.036	0.964	0.000
Y48.5 Therapeutic gases	0.036	0.964	0.000
Y48.1 Parenteral anaesthetics	0.036	0.964	0.000
Y48.0 Inhaled anaesthetics	0.036	0.964	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.036	0.964	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.036	0.964	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.036	0.964	0.000
Y54.3 Benzothiadiazine derivatives	0.036	0.964	0.000
Y46.7 Anti-Parkinsonism drugs	0.035	0.964	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.035	0.965	0.000
Y55.4 Expectorants	0.034	0.966	0.000
Y53.6 Antidiarrhoeal drugs	0.034	0.966	0.000
O72.1 Other immediate postpartum haemorrhage	0.034	0.966	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.034	0.966	0.000
Y44 Agents primarily affecting blood constituents	0.034	0.966	0.000
Y46.6 Other and unspecified antiepileptics	0.034	0.966	0.000
Y54.7 Agents affecting calcification	0.034	0.966	0.000
L40.9 Psoriasis, unspecified	0.000	0.966	0.034
Y49.9 Psychotropic drug, unspecified	0.034	0.966	0.000
Y49.7 Psychostimulants with abuse potential	0.034	0.966	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.034	0.966	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.034	0.966	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.034	0.966	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.033	0.967	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.033	0.967	0.000
Y53.7 Emetics	0.033	0.967	0.000
Y53.5 Digestants	0.033	0.967	0.000
Y53.0 Histamine H2-receptor antagonists	0.033	0.967	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.033	0.967	0.000
Y54.9 Mineral salts, not elsewhere classified	0.032	0.967	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.032	0.967	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.032	0.967	0.000
Y55.0 Oxytocic drugs	0.032	0.967	0.000
Y46.4 Iminostilbenes	0.032	0.967	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.032	0.968	0.000
Y46.8 Antispasticity drugs	0.032	0.968	0.000
Y46.5 Valproic acid	0.032	0.968	0.000
Y46.3 Deoxybarbiturates	0.032	0.968	0.000
Y46.1 Oxazolidinediones	0.032	0.968	0.000
Y46.0 Succinimides	0.032	0.968	0.000
Y46.2 Hydantoin derivatives	0.032	0.968	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.032	0.968	0.000
Y53.3 Saline and osmotic laxatives	0.032	0.968	0.000
Y53.4 Other laxatives	0.031	0.969	0.000
Y54.0 Mineralocorticoids	0.031	0.969	0.000
Y54.4 Loop [high-ceiling] diuretics	0.031	0.969	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.031	0.969	0.000
Y55.5 Anticommon cold drugs	0.031	0.969	0.000
Y55.3 Antitussives	0.031	0.969	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.031	0.969	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.031	0.969	0.000
Y47.1 Benzodiazepines	0.030	0.969	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.030	0.970	0.000
Y54.8 Agents affecting uric acid metabolism	0.030	0.970	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.029	0.970	0.000
C65 Malignant neoplasm of renal pelvis	0.029	0.971	0.000
Y58.0 BCG vaccine	0.029	0.971	0.000
Y49.2 Other and unspecified antidepressants	0.029	0.971	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.029	0.971	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.029	0.971	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.029	0.971	0.000
Y47.4 Bromine compounds	0.029	0.971	0.000
Y47.3 Paraldehyde	0.029	0.971	0.000
Y47.2 Chloral derivatives	0.029	0.971	0.000
Y47.0 Barbiturates, not elsewhere classified	0.029	0.971	0.000
Y42.1 Thyroid hormones and substitutes	0.029	0.971	0.000
Y58.9 Other and unspecified bacterial vaccines	0.028	0.971	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.028	0.971	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.028	0.971	0.000
Y58.5 Diphtheria vaccine	0.028	0.971	0.000
Y58.4 Tetanus vaccine	0.028	0.971	0.000
Y58.3 Plague vaccine	0.028	0.971	0.000
Y58.2 Cholera vaccine	0.028	0.971	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.028	0.971	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.029	0.971	0.000
Y50.9 Central nervous system stimulant, unspecified	0.028	0.972	0.000
Y50.8 Other central nervous system stimulants	0.028	0.972	0.000
Y50.1 Opioid receptor antagonists	0.028	0.972	0.000
Y50.0 Analeptics	0.028	0.972	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.028	0.972	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.027	0.972	0.000
Y42.9 Other and unspecified hormone antagonists	0.027	0.972	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.027	0.973	0.000
Y44.5 Thrombolytic drugs	0.027	0.973	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.027	0.973	0.000
Y59.9 Vaccine or biological substance, unspecified	0.026	0.973	0.000
Y59.8 Other specified vaccines and biological substances	0.026	0.973	0.000
Y59.2 Protozoal vaccines	0.026	0.973	0.000
Y59.1 Rickettsial vaccines	0.026	0.973	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.027	0.973	0.000
K42.9 Umbilical hernia without obstruction or gangrene	0.027	0.973	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.026	0.973	0.000
Y59.3 Immunoglobulin	0.026	0.974	0.000
Y59.0 Viral vaccines	0.025	0.974	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.025	0.975	0.000
Y42.2 Antithyroid drugs	0.025	0.975	0.000
Y42.4 Oral contraceptives	0.025	0.975	0.000
Y41.1 Antimycobacterial drugs	0.025	0.975	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.025	0.975	0.000
Y44.7 Plasma substitutes	0.025	0.975	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.025	0.975	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.024	0.975	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.024	0.976	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.024	0.976	0.000
Y41.4 Anthelminthics	0.024	0.976	0.000
Y41.3 Other antiprotozoal drugs	0.024	0.976	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.024	0.976	0.000
C68.0 Urethra	0.024	0.976	0.000
Y41.5 Antiviral drugs	0.023	0.977	0.000
Y42.7 Androgens and anabolic congeners	0.023	0.977	0.000
Y44.6 Natural blood and blood products	0.023	0.977	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.023	0.977	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.022	0.977	0.000
C68.8 Overlapping lesion of urinary organs	0.022	0.978	0.000
C68.1 Paraurethral glands	0.022	0.978	0.000
Y41.0 Sulphonamides	0.022	0.978	0.000
Y56.9 Topical agent, unspecified	0.022	0.978	0.000
Y56.8 Other topical agents	0.022	0.978	0.000
Y56.7 Dental drugs, topically applied	0.022	0.978	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.022	0.978	0.000
Y56.5 Ophthalmological drugs and preparations	0.022	0.978	0.000
Y56.2 Local astringents and local detergents	0.022	0.978	0.000
Y56.1 Antipruritics	0.022	0.978	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.022	0.978	0.000
Y42.5 Other oestrogens and progestogens	0.022	0.978	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.021	0.979	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.020	0.980	0.000
Y57 Other and unspecified drugs and medicaments	0.020	0.980	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.020	0.980	0.000
C68.9 Urinary organ, unspecified	0.020	0.980	0.000
Y56.3 Emollients, demulcents and protectants	0.020	0.980	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.019	0.980	0.000
Y44.2 Anticoagulants	0.019	0.981	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.019	0.981	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.019	0.981	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.019	0.981	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.019	0.981	0.000
Y51.0 Anticholinesterase agents	0.019	0.981	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.018	0.981	0.000
Y43 Primarily systemic agents	0.019	0.981	0.000
L03.3 Cellulitis of trunk	0.000	0.981	0.019
Y40 Systemic antibiotics	0.018	0.982	0.000
R59.0 Localised enlarged lymph nodes	0.000	0.982	0.018
O97 Death from sequelae of direct obstetric causes	0.017	0.983	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.017	0.983	0.000
O95 Obstetric death of unspecified cause	0.017	0.983	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.017	0.983	0.000
O72 Postpartum haemorrhage	0.016	0.984	0.000
N32.8 Other specified disorders of bladder	0.016	0.984	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.015	0.984	0.000
Y43.0 Antiallergic and antiemetic drugs	0.015	0.985	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.015	0.985	0.000
H92.0 Otalgia	0.000	0.985	0.015
Y40.6 Rifamycins	0.015	0.985	0.000
Y57.5 X-ray contrast media	0.015	0.985	0.000
Y57.7 Vitamins, not elsewhere classified	0.015	0.985	0.000
Y57.4 Pharmaceutical excipients	0.015	0.985	0.000
Y57.3 Alcohol deterrents	0.015	0.985	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.015	0.985	0.000
Y57.1 Lipotropic drugs	0.015	0.985	0.000
Y57.0 Appetite depressants [anorectics]	0.015	0.985	0.000
K42 Umbilical hernia	0.014	0.986	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.014	0.986	0.000
Y40.5 Aminoglycosides	0.014	0.986	0.000
Y43.2 Antineoplastic natural products	0.014	0.986	0.000
Y43.9 Primarily systemic agent, unspecified	0.013	0.986	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.013	0.986	0.000
Y43.6 Enzymes, not elsewhere classified	0.013	0.986	0.000
Y43.5 Acidifying and alkalising agents	0.013	0.986	0.000
Y40.2 Chloramphenicol group	0.013	0.987	0.000
Y43.4 Immunosuppressive agents	0.013	0.987	0.000
Y57.6 Other diagnostic agents	0.013	0.987	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.013	0.987	0.000
O96.9 Death from unspecified obstetric cause	0.012	0.988	0.000
O96.1 Death from indirect obstetric cause	0.012	0.988	0.000
O96.0 Death from direct obstetric cause	0.012	0.988	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.012	0.988	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.012	0.988	0.000
O97.0 Death from sequelae of direct obstetric cause	0.012	0.988	0.000
K42.0 Umbilical hernia with obstruction, without gangrene	0.012	0.988	0.000
Y40.0 Penicillins	0.012	0.988	0.000
Y40.7 Antifungal antibiotics, systemically used	0.012	0.988	0.000
O72.3 Postpartum coagulation defects	0.012	0.988	0.000
Y40.9 Systemic antibiotic, unspecified	0.012	0.988	0.000
Y40.3 Macrolides	0.011	0.989	0.000
Y57.8 Other drugs and medicaments	0.011	0.989	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
Y40.4 Tetracyclines	0.010	0.989	0.000
H43 Disorders of vitreous body	0.000	0.989	0.011
K42.1 Umbilical hernia with gangrene	0.010	0.990	0.000
H43.1 Vitreous haemorrhage	0.000	0.990	0.010
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.010	0.990	0.000
M54.56 Low back pain (Lumbar region)	0.010	0.990	0.000
H43.8 Other disorders of vitreous body	0.000	0.990	0.010
O72.0 Third-stage haemorrhage	0.010	0.990	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.990	0.010
D86 Sarcoidosis	0.000	0.990	0.010
H43.9 Disorder of vitreous body, unspecified	0.000	0.990	0.009
D80 Immunodeficiency with predominantly antibody defects	0.000	0.991	0.009
D84 Other immunodeficiencies	0.000	0.991	0.009
D86.0 Sarcoidosis of lung	0.000	0.991	0.009
Y57.9 Drug or medicament, unspecified	0.009	0.991	0.000
H43.3 Other vitreous opacities	0.000	0.991	0.009
D80-D89 Certain disorders involving the immune mechanism	0.000	0.991	0.009
D84.9 Immunodeficiency, unspecified	0.000	0.991	0.009
Y40.8 Other systemic antibiotics	0.009	0.991	0.000
H43.2 Crystalline deposits in vitreous body	0.000	0.991	0.009
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.991	0.009
D86.1 Sarcoidosis of lymph nodes	0.000	0.992	0.008
H11.9 Disorder of conjunctiva, unspecified	0.000	0.992	0.008
D84.8 Other specified immunodeficiencies	0.000	0.992	0.008
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.992	0.008
H92 Otalgia and effusion of ear	0.000	0.992	0.008
H11 Other disorders of conjunctiva	0.000	0.992	0.008
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.992	0.008
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.992	0.008
Y43.1 Antineoplastic antimetabolites	0.007	0.992	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.992	0.007
D83 Common variable immunodeficiency	0.000	0.992	0.007
H11.3 Conjunctival haemorrhage	0.000	0.993	0.007
K60.3 Anal fistula	0.000	0.993	0.007
D86.3 Sarcoidosis of skin	0.000	0.993	0.007
L40 Psoriasis	0.000	0.993	0.007
H43.0 Vitreous prolapse	0.000	0.993	0.007
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.993	0.007
D84.1 Defects in the complement system	0.000	0.993	0.007
S42.10 Fracture of scapula (closed)	0.007	0.993	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.993	0.007
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.993	0.007
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.993	0.007
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.993	0.007
R27.0 Ataxia, unspecified	0.007	0.993	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.993	0.007
D81 Combined immunodeficiencies	0.000	0.993	0.007
R90.0 Intracranial space-occupying lesion	0.000	0.993	0.007
R45.8 Other symptoms and signs involving emotional state	0.007	0.993	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.006	0.993	0.000
D82 Immunodeficiency associated with other major defects	0.000	0.993	0.006
H92.1 Otorrhoea	0.000	0.993	0.007
N81.4 Uterovaginal prolapse, unspecified	0.007	0.993	0.000
D83.9 Common variable immunodeficiency, unspecified	0.000	0.994	0.006
M47.99 Spondylosis, unspecified (Site unspecified)	0.006	0.994	0.000
Z83.5 Family history of eye and ear disorders	0.006	0.994	0.000
L40.4 Guttate psoriasis	0.000	0.994	0.006
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.994	0.006
C44.6 Skin of upper limb, including shoulder	0.006	0.994	0.000
N81 Female genital prolapse	0.006	0.994	0.000
H10-H13 Disorders of conjunctiva	0.000	0.994	0.006
H11.2 Conjunctival scars	0.000	0.994	0.006
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.994	0.005
D83.8 Other common variable immunodeficiencies	0.000	0.994	0.005
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.994	0.005
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.994	0.005
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.994	0.005
L40.1 Generalised pustular psoriasis	0.000	0.994	0.006
A04.8 Other specified bacterial intestinal infections	0.006	0.994	0.000
S13.4 Sprain and strain of cervical spine	0.000	0.994	0.006
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.006	0.994	0.000
N32 Other disorders of bladder	0.006	0.994	0.000
H92.2 Otorrhagia	0.000	0.994	0.005
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.000	0.994	0.006
D86.8 Sarcoidosis of other and combined sites	0.000	0.994	0.005
H11.1 Conjunctival degenerations and deposits	0.000	0.995	0.005
L40.2 Acrodermatitis continua	0.000	0.995	0.005
H13 Disorders of conjunctiva in diseases classified elsewhere	0.000	0.995	0.005
L40.3 Pustulosis palmaris et plantaris	0.000	0.995	0.005
R90 Abnormal findings on diagnostic imaging of central nervous system	0.000	0.995	0.005
H10 Conjunctivitis	0.000	0.995	0.005
H43-H45 Disorders of vitreous body and globe	0.000	0.995	0.005
D81.9 Combined immunodeficiency, unspecified	0.000	0.995	0.005
D81.8 Other combined immunodeficiencies	0.000	0.995	0.005
D81.7 Major histocompatibility complex class II deficiency	0.000	0.995	0.005
D81.6 Major histocompatibility complex class I deficiency	0.000	0.995	0.005
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.995	0.005
D81.4 Nezelof's syndrome	0.000	0.995	0.005
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.995	0.005
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.995	0.005
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.995	0.005
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.995	0.005
M48.09 Spinal stenosis (Site unspecified)	0.005	0.995	0.000
H13.3 Ocular pemphigoid	0.000	0.995	0.005
D82.1 Di George's syndrome	0.000	0.995	0.005
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.995	0.005
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.995	0.005
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.995	0.005
D82.2 Immunodeficiency with short-limbed stature	0.000	0.995	0.005
D82.0 Wiskott-Aldrich syndrome	0.000	0.995	0.005
H11.8 Other specified disorders of conjunctiva	0.000	0.995	0.005
H10.9 Conjunctivitis, unspecified	0.000	0.995	0.005
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.995	0.004
L40.8 Other psoriasis	0.000	0.996	0.004
H13.1 Conjunctivitis in infectious and parasitic diseases classified elsewhere	0.000	0.996	0.004
Z57.5 Occupational exposure to toxic agents in other industries	0.004	0.996	0.000
H44.2 Degenerative myopia	0.000	0.996	0.004
H10.4 Chronic conjunctivitis	0.000	0.996	0.004
N32.2 Vesical fistula, not elsewhere classified	0.004	0.996	0.000
N32.9 Bladder disorder, unspecified	0.004	0.996	0.000
S72.10 Pertrochanteric fracture (closed)	0.000	0.996	0.004
N32.4 Rupture of bladder, nontraumatic	0.004	0.996	0.000
H44 Disorders of globe	0.000	0.996	0.004
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.996	0.004
H13.8 Other disorders of conjunctiva in diseases classified elsewhere	0.000	0.996	0.004
H13.2 Conjunctivitis in other diseases classified elsewhere	0.000	0.996	0.004
H13.0 Filarial infection of conjunctiva	0.000	0.996	0.004
H10.8 Other conjunctivitis	0.000	0.996	0.004
A04 Other bacterial intestinal infections	0.004	0.996	0.000
L40.0 Psoriasis vulgaris	0.000	0.996	0.004
E78.0 Pure hypercholesterolaemia	0.004	0.996	0.000
H10.2 Other acute conjunctivitis	0.000	0.996	0.004
H10.5 Blepharoconjunctivitis	0.000	0.996	0.004
N32.0 Bladder-neck obstruction	0.004	0.996	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.000	0.996	0.004
H10.3 Acute conjunctivitis, unspecified	0.000	0.996	0.004
A04.7 Enterocolitis due to Clostridium difficile	0.004	0.996	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.000	0.996	0.004
H10.1 Acute atopic conjunctivitis	0.000	0.996	0.004
H10.0 Mucopurulent conjunctivitis	0.000	0.996	0.004
H11.0 Pterygium	0.000	0.996	0.004
N81.0 Female urethrocele	0.004	0.996	0.000
S13.1 Dislocation of cervical vertebra	0.000	0.996	0.004
R04.2 Haemoptysis	0.000	0.996	0.004
R59 Enlarged lymph nodes	0.000	0.996	0.004
H44.8 Other disorders of globe	0.000	0.996	0.003
A04.9 Bacterial intestinal infection, unspecified	0.003	0.996	0.000
N32.3 Diverticulum of bladder	0.004	0.996	0.000
N32.1 Vesicointestinal fistula	0.003	0.996	0.000
A04.4 Other intestinal Escherichia coli infections	0.003	0.997	0.000
N81.8 Other female genital prolapse	0.003	0.997	0.000
S42.1 Fracture of scapula	0.003	0.997	0.000
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.000	0.997	0.003
H44.6 Retained (old) intraocular foreign body, magnetic	0.000	0.997	0.003
H44.3 Other degenerative disorders of globe	0.000	0.997	0.003
L40-L45 Papulosquamous disorders	0.000	0.997	0.003
D89.3 Immune reconstitution syndrome	0.000	0.997	0.003
A04.6 Enteritis due to Yersinia enterocolitica	0.003	0.997	0.000
A04.3 Enterohaemorrhagic Escherichia coli infection	0.003	0.997	0.000
A04.2 Enteroinvasive Escherichia coli infection	0.003	0.997	0.000
A04.1 Enterotoxigenic Escherichia coli infection	0.003	0.997	0.000
A04.0 Enteropathogenic Escherichia coli infection	0.003	0.997	0.000
H44.4 Hypotony of eye	0.000	0.997	0.003
H44.1 Other endophthalmitis	0.000	0.997	0.003
H45.8 Other disorders of vitreous body and globe in diseases classified elsewhere	0.000	0.997	0.003
H45.1 Endophthalmitis in diseases classified elsewhere	0.000	0.997	0.003
H45.0 Vitreous haemorrhage in diseases classified elsewhere	0.000	0.997	0.003
H44.0 Purulent endophthalmitis	0.000	0.997	0.003
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.997	0.003
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.000	0.997	0.003
S13.5 Sprain and strain of thyroid region	0.000	0.997	0.003
S13.3 Multiple dislocations of neck	0.000	0.997	0.003
S13.2 Dislocation of other and unspecified parts of neck	0.000	0.997	0.003
S13.0 Traumatic rupture of cervical intervertebral disk	0.000	0.997	0.003
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.997	0.003
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.997	0.003
Z57.3 Occupational exposure to other air contaminants	0.003	0.997	0.000
Z57 Occupational exposure to risk-factors	0.003	0.997	0.000
A04.5 Campylobacter enteritis	0.003	0.997	0.000
D89.1 Cryoglobulinaemia	0.000	0.997	0.003
N81.9 Female genital prolapse, unspecified	0.003	0.997	0.000
L42 Pityriasis rosea	0.000	0.997	0.003
C22.0 Liver cell carcinoma	0.003	0.997	0.000
R57.0 Cardiogenic shock	0.003	0.997	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.000	0.997	0.003
H44.5 Degenerated conditions of globe	0.000	0.997	0.003
H44.9 Disorder of globe, unspecified	0.000	0.997	0.003
Z57.8 Occupational exposure to other risk-factors	0.003	0.997	0.000
N81.5 Vaginal enterocele	0.003	0.997	0.000
D41.4 Bladder	0.003	0.997	0.000
J86.9 Pyothorax without fistula	0.000	0.997	0.003
Z80.9 Family history of malignant neoplasm, unspecified	0.003	0.997	0.000
L44 Other papulosquamous disorders	0.000	0.997	0.003
S10.9 Superficial injury of neck, part unspecified	0.000	0.997	0.003
S42.11 Fracture of scapula (open)	0.003	0.997	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.003	0.997	0.000
R59.1 Generalised enlarged lymph nodes	0.000	0.997	0.003
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.997	0.003
L41 Parapsoriasis	0.000	0.997	0.003
M13.99 Arthritis, unspecified (Site unspecified)	0.003	0.997	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.003	0.997	0.000
D12.3 Transverse colon	0.003	0.997	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.003	0.997	0.000
R73.0 Abnormal glucose tolerance test	0.003	0.997	0.000
Y43.3 Other antineoplastic drugs	0.003	0.997	0.000
S65.5 Injury of blood vessel(s) of other finger	0.002	0.997	0.000
R52.2 Other chronic pain	0.003	0.997	0.000
R27 Other lack of coordination	0.002	0.998	0.000
I27.0 Primary pulmonary hypertension	0.000	0.998	0.002
Z57.9 Occupational exposure to unspecified risk-factor	0.002	0.998	0.000
Z57.7 Occupational exposure to vibration	0.002	0.998	0.000
Z57.6 Occupational exposure to extreme temperature	0.002	0.998	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.002	0.998	0.000
Z57.1 Occupational exposure to radiation	0.002	0.998	0.000
Z57.0 Occupational exposure to noise	0.002	0.998	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.002	0.998	0.000
K74.0 Hepatic fibrosis	0.002	0.998	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.998	0.002
L44.0 Pityriasis rubra pilaris	0.000	0.998	0.002
L43 Lichen planus	0.000	0.998	0.002
M96.5 Postradiation scoliosis	0.002	0.998	0.000
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
L44.9 Papulosquamous disorder, unspecified	0.000	0.998	0.002
L44.8 Other specified papulosquamous disorders	0.000	0.998	0.002
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.000	0.998	0.002
L44.3 Lichen ruber moniliformis	0.000	0.998	0.002
L44.2 Lichen striatus	0.000	0.998	0.002
L44.1 Lichen nitidus	0.000	0.998	0.002
L41.9 Parapsoriasis, unspecified	0.000	0.998	0.002
L41.8 Other parapsoriasis	0.000	0.998	0.002
L41.5 Retiform parapsoriasis	0.000	0.998	0.002
L41.4 Large plaque parapsoriasis	0.000	0.998	0.002
L41.3 Small plaque parapsoriasis	0.000	0.998	0.002
L41.2 Lymphomatoid papulosis	0.000	0.998	0.002
L41.0 Pityriasis lichenoides et varioliformis acuta	0.000	0.998	0.002
D47.3 Essential (haemorrhagic) thrombocythaemia	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations